Publications 2022

Vedeld HM, Grimsrud MM, Andresen K, Pharo HD, von Seth E, Karlsen TH, Honne H, Paulsen V, Farkkila MA, Bergquist A, Jeanmougin M, Aabakken L, Boberg KM, Folseraas T, Lind GE (2022)
Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
Hepatology, 75 (1), 59-73
DOI 10.1002/hep.32125

Publications 2021

Bossen L, Vesterhus M, Hov JR, Farkkila M, Rosenberg WM, Moller HJ, Boberg KM, Karlsen TH, Gronbaek H (2021)
Circulating Macrophage Activation Markers Predict Transplant-Free Survival in Patients With Primary Sclerosing Cholangitis
Clin. Transl. Gastroenterol., 12 (3), e00315
DOI 10.14309/ctg.0000000000000315

Ponsioen CY, Assis DN, Boberg KM, Bowlus CL, Deneau M, Thorburn D, Aabakken L, Farkkila M, Petersen B, Rupp C, Hubscher SG, Int PSC Study Grp (2021)
Defining Primary Sclerosing Cholangitis: Results From an International Primary Sclerosing Cholangitis Study Group Consensus Process COMMENT
Gastroenterology, 161 (6), 1764-+
DOI 10.1053/j.gastro.2021.07.046

Vesterhus M, Nielsen MJ, Hov JR, Saffioti F, Manon-Jensen T, Leeming DJ, Moum B, Boberg KM, Pinzani M, Karlsen TH, Karsdal MA, Thorburn D (2021)
Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease
JHEP Rep., 3 (1), 100178
DOI 10.1016/j.jhepr.2020.100178

Publications 2020

Goeppert B, Folseraas T, Roessler S, Kloor M, Volckmar AL, Endris V, Buchhalter I, Stenzinger A, Grzyb K, Grimsrud MM, Gornicka B, von Seth E, Reynolds GM, Franke A, Gotthardt DN, Mehrabi A, Cheung A, Verheij J, Arola J, Makisalo H, Eide TJ, Weidemann S, Cheville JC, Mazza G, Hirschfield GM et al. (2020)
Genomic Characterization of Cholangiocarcinoma in Primary Sclerosing Cholangitis Reveals Therapeutic Opportunities
Hepatology, 72 (4), 1253-1266
DOI 10.1002/hep.31110

Publications 2019

Dhillon AK, Kremer AE, Kummen M, Boberg KM, Elferink RPO, Karlsen TH, Beuers U, Vesterhus M, Hov JR (2019)
Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis
Sci Rep, 9, 8450
DOI 10.1038/s41598-019-44762-7

Saffioti F, Roccarina D, Vesterhus M, Hov JR, Rosenberg W, Pinzani M, Pereira SP, Boberg KM, Thorburn D (2019)
Cholangiocarcinoma is associated with a raised enhanced liver fibrosis score independent of primary sclerosing cholangitis
Eur. J. Clin. Invest., 49 (5), e13088
DOI 10.1111/eci.13088

Publications 2018

Aberg F, Isoniemi H, Pukkala E, Jalanko H, Rasmussen A, Storm HH, Schultz N, Bennet W, Ekvall N, Ericzon BG, Malenicka S, Tretli S, Line PD, Boberg KM, Ostensen A, Karlsen TH, Nordin A (2018)
Cancer After Liver Transplantation in Children and Young Adults: A Population-Based Study From 4 Nordic Countries
Liver Transplant., 24 (9), 1252-1259
DOI 10.1002/lt.25305

Alberts R, de Vries EMG, Goode EC, Jiang XJ, Sampaziotis F, Rombouts K, Bottcher K, Folseraas T, Weismuller TJ, Mason AL, Wang WW, Alexander G, Alvaro D, Bergquist A, Bjorkstrom NK, Beuers U, Bjornsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouilleres O, Cheung A, Dalekos G, Eaton J et al. (2018)
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis
Gut, 67 (8), 1517-1524
DOI 10.1136/gutjnl-2016-313598

Lindstrom L, Jorgensen KK, Boberg KM, Castedal M, Rasmussen A, Rostved AA, Isoniemi H, Bottai M, Bergquist A (2018)
Risk factors and prognosis for recurrent primary sclerosing cholangitis after liver transplantation: a Nordic Multicentre Study
Scand. J. Gastroenterol., 53 (3), 297-304
DOI 10.1080/00365521.2017.1421705

Nielsen MJ, Thorburn D, Leeming DJ, Hov JR, Nygard S, Moum B, Saffioti F, Gilja OH, Boberg KM, Mazza G, Rosjo H, Pinzani M, Karlsen TH, Karsdal MA, Vesterhus M (2018)
Serological markers of extracellular matrix remodeling predict transplant-free survival in primary sclerosing cholangitis
Aliment. Pharmacol. Ther., 48 (2), 179-189
DOI 10.1111/apt.14806

Nordin A, Aberg F, Pukkala E, Pedersen CR, Storm HH, Rasmussen A, Bennet W, Olausson M, Wilczek H, Ericzon BG, Tretli S, Line PD, Karlsen TH, Boberg KM, Isoniemi H (2018)
Decreasing incidence of cancer after liver transplantationA Nordic population-based study over 3 decades
Am. J. Transplant., 18 (4), 952-963
DOI 10.1111/ajt.14507

Publications 2017

de Vries EM, Farkkila M, Milkiewicz P, Hov JR, Eksteen B, Thorburn D, Chazouilleres O, Pares A, Nygard S, Gilja OH, Wunsch E, Invernizzi P, Carbone M, Bernuzzi F, Boberg KM, Rosjo H, Rosenberg W, Beuers UH, Ponsioen CY, Karlsen TH, Vesterhus M (2017)
Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study
Liver Int., 37 (10), 1554-1561
DOI 10.1111/liv.13402

Dueland S, Guren TK, Boberg KM, Reims HM, Grzyb K, Aamdal S, Julsrud L, Line PD (2017)
Acute liver graft rejection after ipilimumab therapy
Ann. Oncol., 28 (10), 2619-2620
DOI 10.1093/annonc/mdx281

Henriksen EKK, Jorgensen KK, Kaveh F, Holm K, Hamm D, Olweus J, Melum E, Chung BK, Eide TJ, Lundin KEA, Boberg KM, Karlsen TH, Hirschfield GM, Liaskou E (2017)
Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease
J. Hepatol., 66 (1), 116-122
DOI 10.1016/j.jhep.2016.09.002

Hov JR, Boberg KM, Taraldsrud E, Vesterhus M, Boyadzhieva M, Solberg IC, Schrumpf E, Vatn MH, Lie BA, Molberg O, Karlsen TH (2017)
Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis
Liver Int., 37 (3), 458-465
DOI 10.1111/liv.13238

Ji SG, Juran BD, Mucha S, Folseraas T, Jostins L, Melum E, Kumasaka N, Atkinson EJ, Schlicht EM, Liu JZ, Shah T, Gutierrez-Achury J, Boberg KM, Bergquist A, Vermeire S, Eksteen B, Durie PR, Farkkila M, Muller T, Schramm C, Sterneck M, Weismuller TJ, Gotthardt DN, Ellinghaus D, Braun F et al. (2017)
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
Nature Genet., 49 (2), 269-273
DOI 10.1038/ng.3745

Kummen M, Vesterhus M, Troseid M, Moum B, Svardal A, Boberg KM, Aukrust P, Karlsen TH, Berge RK, Hov JR (2017)
Elevated trimethylamine-N-oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function
United European Gastroenterol. J., 5 (4), 532-541
DOI 10.1177/2050640616663453

Vesterhus M, Holm A, Hov JR, Nygard S, Schrumpf E, Melum E, Thorbjornsen LW, Paulsen V, Lundin K, Dale I, Gilja OH, Zweers SJLB, Vatn M, Schaap FG, Jansen PLM, Ueland T, Rosjo H, Moum B, Ponsioen CY, Boberg KM, Farkkila M, Karlsen TH, Lund-Johansen F (2017)
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
J. Hepatol., 66 (6), 1214-1222
DOI 10.1016/j.jhep.2017.01.019

Weismuller TJ, Trivedi PJ, Bergquist A, Imam M, Lenzen H, Ponsioen CY, Holm K, Gotthardt D, Farkkila MA, Marschall HU, Thorburn D, Weersma RK, Fevery J, Mueller T, Chazouilleres O, Schulze K, Lazaridis KN, Almer S, Pereira SP, Levy C, Mason A, Naess S, Bowlus CL, Floreani A, Halilbasic E et al. (2017)
Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis
Gastroenterology, 152 (8), 1975-+
DOI 10.1053/j.gastro.2017.02.038

Publications 2016

Banales JM, Cardinale V, Carpino G, Marzioni M, Andersen J, Invernizzi P, Lind GE, Folseraas T, Forbes SJ, Fouassier L, Geier A, Calvisi DF, Mertens JC, Trauner M, Benedetti A, Maroni L, Vaquero J, Macias RIR, Raggi C, Perugorria MJ, Gaudio E, Boberg KM, Marin JJG, Alvaro D (2016)
Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
Nat. Rev. Gastroenterol. Hepatol., 13 (5), 261-280
DOI 10.1038/nrgastro.2016.51

Bernuzzi F, Marabita F, Lleo A, Carbone M, Mirolo M, Marzioni M, Alpini G, Alvaro D, Boberg KM, Locati M, Torzilli G, Rimassa L, Piscaglia F, He XS, Bowlus CL, Yang GX, Gershwin ME, Invernizzi P (2016)
Serum microRNAs as novel biomarkers for primary sclerosing cholangitis and cholangiocarcinoma
Clin. Exp. Immunol., 185 (1), 61-71
DOI 10.1111/cei.12776

Folseraas T, Boberg KM (2016)
Cancer Risk and Surveillance in Primary Sclerosing Cholangitis
Clin. Liver Dis., 20 (1), 79-+
DOI 10.1016/j.cld.2015.08.014

Harbord M, Annese V, Vavricka SR, Allez M, Barreiro-de Acosta M, Boberg KM, Burisch J, De Vos M, De Vries AM, Dick AD, Juillerat P, Karlsen TH, Koutroubakis I, Lakatos PL, Orchard T, Papay P, Raine T, Reinshagen M, Thaci D, Tilg H, Carbonnel F, European Crohn's Colitis Org ECCO (2016)
The First European Evidence-based Consensus on Extra-intestinal Manifestations in Inflammatory Bowel Disease
J. Crohns Colitis, 10 (3), 239-254
DOI 10.1093/ecco-jcc/jjv213

Zenouzi R, Weismuller TJ, Jorgensen KK, Bubenheim M, Lenzen H, Hubener P, Schulze K, Weiler-Normann C, Sebode M, Ehlken H, Pannicke N, Hartl J, Peiseler M, Hubener S, Karlsen TH, Boberg KM, Manns MP, Lohse AW, Schramm C (2016)
No Evidence That Azathioprine Increases Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis
Clin. Gastroenterol. Hepatol., 14 (12), 1806-1812
DOI 10.1016/j.cgh.2016.07.032

Publications 2015

Aberg F, Gissler M, Karlsen TH, Ericzon BG, Foss A, Rasmussen A, Bennet W, Olausson M, Line PD, Nordin A, Bergquist A, Boberg KM, Castedal M, Pedersen CR, Isoniemi H (2015)
Differences in Long-Term Survival Among Liver Transplant Recipients and the General Population: A Population-Based Nordic Study
Hepatology, 61 (2), 668-677
DOI 10.1002/hep.27538

Andersen IM, Fosby B, Boberg KM, Clausen OPF, Jebsen P, Melum E, Line PD, Foss A, Schrumpf E, Karlsen TH (2015)
Indications and Outcomes in Liver Transplantation in Patients With Primary Sclerosing Cholangitis in Norway
Transplant. Direct., 1 (9), e39
DOI 10.1097/TXD.0000000000000548

Andresen K, Boberg KM, Vedeld HM, Honne H, Jebsen P, Hektoen M, Wadsworth CA, Clausen OP, Lundin KEA, Paulsen V, Foss A, Mathisen O, Aabakken L, Schrumpf E, Lothe RA, Lind GE (2015)
Four DNA Methylation Biomarkers in Biliary Brush Samples Accurately Identify the Presence of Cholangiocarcinoma
Hepatology, 61 (5), 1651-1659
DOI 10.1002/hep.27707

Berntsen NL, Klingenberg O, Juran BD, de Valle MB, Lindkvist B, Lazaridis KN, Boberg KM, Karlsen TH, Hov JR (2015)
Association Between HLA Haplotypes and Increased Serum Levels of IgG4 in Patients With Primary Sclerosing Cholangitis
Gastroenterology, 148 (5), 924-U355
DOI 10.1053/j.gastro.2015.01.041

Fosby B, Melum E, Bjoro K, Bennet W, Rasmussen A, Andersen IM, Castedal M, Olausson M, Wibeck C, Gotlieb M, Gjertsen H, Toivonen L, Foss S, Makisalo H, Nordin A, Sanengen T, Bergquist A, Larsson ME, Soderdahl G, Nowak G, Boberg KM, Isoniemi H, Keiding S, Foss A, Line PD et al. (2015)
Liver transplantation in the Nordic countries - An intention to treat and post-transplant analysis from The Nordic Liver Transplant Registry 1982-2013
Scand. J. Gastroenterol., 50 (6), 797-808
DOI 10.3109/00365521.2015.1036359

Schrumpf E, Boberg KM, Karlsen TH (2015)
Primary sclerosing cholangitis - the Norwegian experience
Scand. J. Gastroenterol., 50 (6), 781-796
DOI 10.3109/00365521.2015.1028996

Thorsen T, Dahlgren US, Aandahl EM, Grzyb K, Karlsen TH, Boberg KM, Rydberg L, Naper C, Foss A, Bennet W (2015)
Liver transplantation with deceased ABO-incompatible donors is life-saving but associated with increased risk of rejection and post-transplant complications
Transpl. Int., 28 (7), 800-812
DOI 10.1111/tri.12552

Vedeld HM, Andresen K, Eilertsen IA, Nesbakken A, Seruca R, Gladhaug IP, Thiis-Evensen E, Rognum TO, Boberg KM, Lind GE (2015)
The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
Int. J. Cancer, 136 (4), 844-853
DOI 10.1002/ijc.29039

Vesterhus M, Hov JR, Holm A, Schrumpf E, Nygard S, Godang K, Andersen IM, Naess S, Thorburn D, Saffioti F, Vatn M, Gilja OH, Lund-Johansen F, Syversveen T, Brabrand K, Pares A, Ponsioen CY, Pinzani M, Farkkila M, Moum B, Ueland T, Rosjo H, Rosenberg W, Boberg KM, Karlsen TH (2015)
Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis
Hepatology, 62 (1), 188-197
DOI 10.1002/hep.27825

Publications 2014

Andersen IM, Tengesdal G, Lie BA, Boberg KM, Karlsen TH, Hov JR (2014)
Effects of Coffee Consumption, Smoking, and Hormones on Risk for Primary Sclerosing Cholangitis
Clin. Gastroenterol. Hepatol., 12 (6), 1019-1028
DOI 10.1016/j.cgh.2013.09.024

Block M, Jorgensen KK, Oresland T, Lindholm E, Grzyb K, Cvancarova M, Vatn MH, Boberg KM, Borjesson L (2014)
Colectomy for patients with ulcerative colitis and primary sclerosing cholangitis - What next?
J. Crohns Colitis, 8 (5), 421-430
DOI 10.1016/j.crohns.2013.10.008

Fosby B, Naess S, Hov JR, Traherne J, Boberg KM, Trowsdale J, Foss A, Line PD, Franke A, Melum E, Scott H, Karlsen TH (2014)
HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation vs
World J. Gastroenterol., 20 (14), 3986-4000
DOI 10.3748/wjg.v20.i14.3986

Karlsen TH, Vesterhus M, Boberg KM (2014)
Review article: controversies in the management of primary biliary cirrhosis and primary sclerosing cholangitis
Aliment. Pharmacol. Ther., 39 (3), 282-301
DOI 10.1111/apt.12581

Naess S, Bjornsson E, Anmarkrud JA, Al Mamari S, Juran BD, Lazaridis KN, Chapman R, Bergquist A, Melum E, Marsh SGE, Schrumpf E, Lie BA, Boberg KM, Karlsen TH, Hov JR (2014)
Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease
Liver Int., 34 (10), 1488-1495
DOI 10.1111/liv.12492

Naess S, Lie BA, Melum E, Olsson M, Hov JR, Croucher PJP, Hampe J, Thorsby E, Bergquist A, Traherne JA, Schrumpf E, Boberg KM, Schreiber S, Franke A, Karlsen TH (2014)
Refinement of the MHC Risk Map in a Scandinavian Primary Sclerosing Cholangitis Population
PLoS One, 9 (12), e114486
DOI 10.1371/journal.pone.0114486

Publications 2013

Boberg KM, Wisloff T, Kjollesdal KS, Stovring H, Kristiansen IS (2013)
Cost and health consequences of treatment of primary biliary cirrhosis with ursodeoxycholic acid
Aliment. Pharmacol. Ther., 38 (7), 794-803
DOI 10.1111/apt.12435

Ellinghaus D, Folseraas T, Holm K, Ellinghaus E, Melum E, Balschun T, Laerdahl JK, Shiryaev A, Gotthardt DN, Weismuller TJ, Schramm C, Wittig M, Bergquist A, Bjornsson E, Marschall HU, Vatn M, Teufel A, Rust C, Gieger C, Wichmann HE, Runz H, Sterneck M, Rupp C, Braun F, Weersma RK et al. (2013)
Genome-Wide Association Analysis in Primary Sclerosing Cholangitis and Ulcerative Colitis Identifies Risk Loci at GPR35 and TCF4
Hepatology, 58 (3), 1074-1083
DOI 10.1002/hep.25977

Hagness M, Foss A, Line PD, Scholz T, Jorgensen PF, Fosby B, Boberg KM, Mathisen O, Gladhaug IP, Egge TS, Solberg S, Hausken J, Dueland S (2013)
Liver Transplantation for Nonresectable Liver Metastases From Colorectal Cancer
Ann. Surg., 257 (5), 800-806
DOI 10.1097/SLA.0b013e3182823957

Jorgensen KK, Lindstrom L, Cvancarova M, Karlsen TH, Castedal M, Friman S, Schrumpf E, Foss A, Isoniemi H, Nordin A, Holte K, Rasmussen A, Bergquist A, Vatn MH, Boberg KM (2013)
Immunosuppression After Liver Transplantation for Primary Sclerosing Cholangitis Influences Activity of Inflammatory Bowel Disease
Clin. Gastroenterol. Hepatol., 11 (5), 517-523
DOI 10.1016/j.cgh.2012.12.027

Karlsen TH, Boberg KM (2013)
Update on primary sclerosing cholangitis
J. Hepatol., 59 (3), 571-582
DOI 10.1016/j.jhep.2013.03.015

Kummen M, Schrumpf E, Boberg KM (2013)
Liver abnormalities in bowel diseases
Best Pract. Res. Clin. Gastroenterol., 27 (4), 531-542
DOI 10.1016/j.bpg.2013.06.013

Lindstrom L, Hultcrantz R, Boberg KM, Friis-Liby I, Bergquist A (2013)
Association Between Reduced Levels of Alkaline Phosphatase and Survival Times of Patients With Primary Sclerosing Cholangitis
Clin. Gastroenterol. Hepatol., 11 (7), 841-846
DOI 10.1016/j.cgh.2012.12.032

Liu JZ, Hov JR, Folseraas T, Ellinghaus E, Rushbrook SM, Doncheva NT, Andreassen OA, Weersma RK, Weismuller TJ, Eksteen B, Invernizzi P, Hirschfield GM, Gotthardt DN, Pares A, Ellinghaus D, Shah T, Juran BD, Milkiewicz P, Rust C, Schramm C, Muller T, Srivastava B, Dalekos G, Nothen MM, Herms S et al. (2013)
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
Nature Genet., 45 (6), 670-+
DOI 10.1038/ng.2616

Wannhoff A, Hov JR, Folseraas T, Rupp C, Friedrich K, Anmarkrud JA, Weiss KH, Sauer P, Schirmacher P, Boberg KM, Stremmel W, Karlsen TH, Gotthardt DN (2013)
FUT2 and FUT3 genotype determines CA19-9 cut-off values for detection of cholangiocarcinoma in patients with primary sclerosing cholangitis
J. Hepatol., 59 (6), 1278-1284
DOI 10.1016/j.jhep.2013.08.005

Publications 2012

Andresen K, Boberg KM, Vedeld HM, Honne H, Hektoen M, Wadsworth CA, Clausen OP, Karlsen TH, Foss A, Mathisen O, Schrumpf E, Lothe RA, Lind GE (2012)
Novel target genes and a valid biomarker panel identified for cholangiocarcinoma
Epigenetics, 7 (11), 1249-1257
DOI 10.4161/epi.22191

Folseraas T, Melum E, Rausch P, Juran BD, Ellinghaus E, Shiryaev A, Laerdahl JK, Ellinghaus D, Schramm C, Weismuller TJ, Gotthard DN, Hov JR, Clausen OP, Weersma RK, Janse M, Boberg KM, Bjornsson E, Marschall HU, Cleynen I, Rosenstiel P, Holm K, Teufel A, Rust C, Gieger C, Wichmann HE et al. (2012)
Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci
J. Hepatol., 57 (2), 366-375
DOI 10.1016/j.jhep.2012.03.031

Haugaa H, Thorgersen EB, Pharo A, Boberg KM, Foss A, Line PD, Sanengen T, Almaas R, Grindheim G, Pischke SE, Mollnes TE, Tonnessen TI (2012)
Early bedside detection of ischemia and rejection in liver transplants by microdialysis
Liver Transplant., 18 (7), 839-849
DOI 10.1002/lt.23425

Haugaa H, Thorgersen EB, Pharo A, Boberg KM, Foss A, Line PD, Sanengen T, Almaas R, Grindheim G, Waelgaard L, Pischke SE, Mollnes TE, Tonnessen TI (2012)
Inflammatory markers sampled by microdialysis catheters distinguish rejection from ischemia in liver grafts
Liver Transplant., 18 (12), 1421-1429
DOI 10.1002/lt.23503

Jorgensen KK, Grzyb K, Lundin KEA, Clausen OPF, Aamodt G, Schrumpf E, Vatn MH, Boberg KM (2012)
Inflammatory bowel disease in patients with primary sclerosing cholangitis: Clinical characterization in liver transplanted and nontransplanted patients
Inflamm. Bowel Dis., 18 (3), 536-545
DOI 10.1002/ibd.21699

Jorgensen KK, Lindstrom L, Cvancarova M, Castedal M, Friman S, Schrumpf E, Foss A, Isoniemi H, Nordin A, Holte K, Rasmussen A, Bergquist A, Vatn MH, Boberg KM (2012)
Colorectal neoplasia in patients with primary sclerosing cholangitis undergoing liver transplantation: a Nordic multicenter study
Scand. J. Gastroenterol., 47 (8-9), 1021-1029
DOI 10.3109/00365521.2012.685754

Lindstrom L, Boberg KM, Wikman O, Friis-Liby I, Hultcrantz R, Prytz H, Sandberg-Gertzen H, Sangfelt P, Rydning A, Folvik G, Gangsoy-Kristiansen M, Danielsson A, Bergquist A (2012)
High dose ursodeoxycholic acid in primary sclerosing cholangitis does not prevent colorectal neoplasia
Aliment. Pharmacol. Ther., 35 (4), 451-457
DOI 10.1111/j.1365-2036.2011.04966.x

Publications 2011

Boberg KM, Chapman RW, Hirschfield GM, Lohse AW, Manns MP, Schrumpf E, Int Autoimmune Hepatitis Grp (2011)
Overlap syndromes: The International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue
J. Hepatol., 54 (2), 374-385
DOI 10.1016/j.jhep.2010.09.002

Boberg KM, Lind GE (2011)
Primary sclerosing cholangitis and malignancy
Best Pract. Res. Clin. Gastroenterol., 25 (6), 753-764
DOI 10.1016/j.bpg.2011.10.002

Hov JR, Kosmoliaptsis V, Traherne JA, Olsson M, Boberg KM, Bergquist A, Schrumpf E, Bradley JA, Taylor CJ, Lie BA, Trowsdale J, Karlsen TH (2011)
Electrostatic Modifications of the Human Leukocyte Antigen-DR P9 Peptide-Binding Pocket and Susceptibility to Primary Sclerosing Cholangitis
Hepatology, 53 (6), 1967-1976
DOI 10.1002/hep.24299

Janse M, Lamberts LE, Franke L, Raychaudhuri S, Ellinghaus E, Boberg KM, Melum E, Folseraas T, Schrumpf E, Bergquist A, Bjornsson E, Fu JY, Westra HJ, Groen HJM, Fehrmann RSN, Smolonska J, van den Berg LH, Ophoff RA, Porte RJ, Weismuller TJ, Wedemeyer J, Schramm C, Sterneck M, Gunther R, Braun F et al. (2011)
Three Ulcerative Colitis Susceptibility Loci Are Associated with Primary Sclerosing Cholangitis and Indicate a Role for IL2, REL, and CARD9
Hepatology, 53 (6), 1977-1985
DOI 10.1002/hep.24307

Melum E, Franke A, Schramm C, Weismuller TJ, Gotthardt DN, Offner FA, Juran BD, Laerdahl JK, Labi V, Bjornsson E, Weersma RK, Henckaerts L, Teufel A, Rust C, Ellinghaus E, Balschun T, Boberg KM, Ellinghaus D, Bergquist A, Sauer P, Ryu E, Hov JR, Wedemeyer J, Lindkvist B, Wittig M et al. (2011)
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci
Nature Genet., 43 (1), 17-19
DOI 10.1038/ng.728

Wiencke K, Boberg KM (2011)
Current consensus on the management of primary sclerosing cholangitis
Clin. Res. Hepatol. Gastroenterol., 35 (12), 786-791
DOI 10.1016/j.clinre.2011.04.007

Publications 2010

Chapman R, Fevery J, Kalloo A, Nagorney DM, Boberg KM, Shneider B, Gores GJ (2010)
Diagnosis and Management of Primary Sclerosing Cholangitis
Hepatology, 51 (2), 660-678
DOI 10.1002/hep.23294

Dolgos S, Hartmann A, Isaksen GA, Simonsen S, Bjortuft O, Boberg KM, Bollerslev J (2010)
Osteoporosis is a prevalent finding in patients with solid organ failure awaiting transplantation - a population based study
Clin. Transplant., 24 (5), E145-E152
DOI 10.1111/j.1399-0012.2010.01231.x

Hov JR, Keitel V, Laerdahl JK, Spomer L, Ellinghaus E, ElSharawy A, Melum E, Boberg KM, Manke T, Balschun T, Schramm C, Bergquist A, Weismuller T, Gotthardt D, Rust C, Henckaerts L, Onnie CM, Weersma RK, Sterneck M, Teufel A, Runz H, Stiehl A, Ponsioen CY, Wijmenga C, Vatn MH et al. (2010)
Mutational Characterization of the Bile Acid Receptor TGR5 in Primary Sclerosing Cholangitis
PLoS One, 5 (8), e12403
DOI 10.1371/journal.pone.0012403

Karlsen TH, Franke A, Melum E, Kaser A, Hov JR, Balschun T, Lie BA, Bergquist A, Schramm C, Weismuller TJ, Gotthardt D, Rust C, Philipp EER, Fritz T, Henckaerts L, Weersma RK, Stokkers P, Ponsioen CY, Wijmenga C, Sterneck M, Nothnagel M, Hampe J, Teufel A, Runz H, Rosenstiel P et al. (2010)
Genome-Wide Association Analysis in Primary Sclerosing Cholangitis
Gastroenterology, 138 (3), 1102-1111
DOI 10.1053/j.gastro.2009.11.046

Karlsen TH, Schrumpf E, Boberg KM (2010)
Update on primary sclerosing cholangitis
Dig. Liver Dis., 42 (6), 390-400
DOI 10.1016/j.dld.2010.01.011

Karlsen TH, Schrumpf E, Boberg KM (2010)
Primary sclerosing cholangitis
Best Pract. Res. Clin. Gastroenterol., 24 (5), 655-666
DOI 10.1016/j.bpg.2010.07.005

Ponsioen CY, Reitsma JB, Boberg KM, Aabakken L, Rauws EAJ, Schrumpf E (2010)
Validation of a cholangiographic prognostic model in primary sclerosing cholangitis
Endoscopy, 42 (9), 742-747
DOI 10.1055/s-0030-1255527

Publications 2009

Forsbring M, Vik ES, Dalhus B, Karlsen TH, Bergquist A, Schrumpf E, Bjoras M, Boberg KM, Alseth I (2009)
Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma
Carcinogenesis, 30 (7), 1147-1154
DOI 10.1093/carcin/bgp118

Yu X, Wieczorek S, Franke A, Yin H, Pierer M, Sina C, Karlsen TH, Boberg KM, Bergquist A, Kunz M, Witte T, Gross WL, Epplen JT, Alarcon-Riquelme ME, Schreiber S, Ibrahim SM (2009)
Association of UCP2-866 G/A polymorphism with chronic inflammatory diseases
Genes Immun., 10 (6), 601-605
DOI 10.1038/gene.2009.29

Publications 2008

Bjornsson E, Olsson R, Bergquist A, Lindgren S, Braden B, Chapman RW, Boberg KM, Angulo P (2008)
The natural history of small-duct primary sclerosing cholangitis
Gastroenterology, 134 (4), 975-980
DOI 10.1053/j.gastro.2008.01.042

Eike MC, Nordang GBN, Karlsen TH, Boberg KM, Vatn MH, Dahl-Jorgensen K, Ronningen KS, Joner G, Flato B, Bergquist A, Thorsby E, Forre O, Kvien TK, Undlien DE, Lie BA, IBSEN Study Grp (2008)
The FCRL3-169T > C polymorphism is associated with rheumatoid arthritis and shows suggestive evidence of involvement with juvenile idiopathic arthritis in a Scandinavian panel of autoimmune diseases
Ann. Rheum. Dis., 67 (9), 1287-1291
DOI 10.1136/ard.2007.077826

Hennes EM, Zeniya M, Czaja AJ, Pares A, Dalekos GN, Krawitt EL, Bittencourt PL, Porta G, Boberg KM, Hofer H, Bianchi FB, Shibata M, Schramm C, de Torres BE, Galle PR, McFarlane I, Dienes HP, Lohse AW, Int Autoimmune Hepatitis Grp (2008)
Simplified criteria for the diagnosis of autoimmune hepatitis
Hepatology, 48 (1), 169-176
DOI 10.1002/hep.22322

Hov JR, Boberg KM, Karlsen TH (2008)
Autoantibodies in primary sclerosing cholangitis
World J. Gastroenterol., 14 (24), 3781-3791
DOI 10.3748/wjg.14.3781

Karlsen TH, Schrumpf E, Boberg KM (2008)
Gallbladder polyps in primary sclerosing cholangitis: not so benign
Curr. Opin. Gastroenterol., 24 (3), 395-399
DOI 10.1097/MOG.0b013e3282f5727a

Melum E, Karlsen TH, Bergquist A, Schrumpf E, Boberg KM (2008)
An interleukin-6 (IL-6) receptor polymorphism affecting serum levels of IL-6 does not increase the risk of cholangiocarcinoma in primary sclerosing cholangitis
Am. J. Gastroenterol., 103 (4), 1045
DOI 10.1111/j.1572-0241.2007.01772_5.x

Melum E, Karlsen TH, Schrumpf E, Bergquist A, Thorsby E, Boberg KM, Lie BA (2008)
Cholanglocarcinoma in primary sclerosing cholangitis is associated with NKG2D Polymorphisms
Hepatology, 47 (1), 90-96
DOI 10.1002/hep.21964

Publications 2007

Karlsen TH, Boberg KM, Olsson M, Sun JY, Senitzer D, Bergquist A, Schrumpf E, Thorsby E, Lie BA (2007)
Particular genetic variants of ligands for natural killer cell receptors may contribute to the HLA associated risk of primary sclerosing cholangitis
J. Hepatol., 46 (5), 899-906
DOI 10.1016/j.jhep.2007.01.032

Karlsen TH, Hampe J, Wiencke K, Schrumpf E, Thorsby E, Lie BA, Broome U, Schreiber S, Boberg KM (2007)
Genetic polymorphisms associated with inflammatory bowel disease do not confer risk for primary sclerosing cholangitis
Am. J. Gastroenterol., 102 (1), 115-121
DOI 10.1111/j.1572-0241.2006.00928.x

Karlsen TH, Schrumpf E, Boberg KM (2007)
Genetic epidemiology of primary sclerosing cholangitis
World J. Gastroenterol., 13 (41), 5421-5431
DOI 10.3748/wjg.v13.i41.5421

Wiencke K, Karlsen TH, Boberg KM, Thorsby E, Schrumpf E, Lie BA, Spurkland A (2007)
Primary sclerosing cholangitis is associated with extended HLA-DR3 and HLA-DR6 haplotypes
Tissue Antigens, 69 (2), 161-169
DOI 10.1111/j.1399-0039.2006.00738.x

Publications 2006

Boberg KM, Jebsen P, Clausen OP, Foss A, Aabakken L, Schrumpf E (2006)
Diagnostic benefit of biliary brush cytology in cholangiocarcinoma in primary sclerosing cholangitis
J. Hepatol., 45 (4), 568-574
DOI 10.1016/j.jhep.2006.05.010

Bowlus CL, Karlsen TH, Broome U, Thorsby E, Vatn M, Schrumpf E, Lie BA, Boberg KM, IBSEN study grp (2006)
Analysis of MAdCAM-1 and ICAM-1 polymorphisms in 365 Scandinavian patients with primary sclerosing cholangitis
J. Hepatol., 45 (5), 704-710
DOI 10.1016/j.jhep.2006.03.012

Karlsen TH, Lie BA, Froslie KF, Thorsby E, Broome U, Schrumpf E, Boberg KM (2006)
Polymorphisms in the steroid and xenobiotic receptor gene influence survival in primary sclerosing cholangitis
Gastroenterology, 131 (3), 781-787
DOI 10.1053/j.gastro.2006.05.057

Melum E, Karlsen TH, Broome U, Thorsby E, Schrumpf E, Boberg KM, Lie BA (2006)
The 32-base pair deletion of the chemokine receptor 5 gene (CCR5-Delta 32) is not associated with primary sclerosing cholangitis in 363 Scandinavian patients
Tissue Antigens, 68 (1), 78-81
DOI 10.1111/j.1399-0039.2006.00604.x

Publications 1990

Boberg KM (1990)
Metabolism and biological effects of some plant sterols
Institute of Clinical Biochemistry, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 900755466, ISBN 82-992151-0-2