Berit Flatø

  • Professor; MD, Dr. med.
  • +47 922 04 543

Senior consultant in pediatric rheumatology

Research topics:
clinical epidemiology, systemic sclerosis, large vessel vasculitis

 

Publications 2024

Sande NK, Kirkhus E, Lilleby V, Tomterstad AH, Aga AB, Flatø B, Bøyesen P (2024)
Validity of an ultrasonographic joint-specific scoring system in juvenile idiopathic arthritis: a cross-sectional study comparing ultrasound findings of synovitis with whole-body magnetic resonance imaging and clinical assessment
RMD Open, 10 (1)
DOI 10.1136/rmdopen-2023-003965, PubMed 38428979

Publications 2023

Kim H, Saygin D, Douglas C, Wilkerson J, Erman B, Pistorio A, McGrath JA, Reed AM, Oddis CV, Bracaglia C, van Royen-Kerkhof A, Bica B, Dolezalova P, Ferriani VPL, Flato B, Bernard-Medina AG, Herlin T, Miller FW, Vencovsky J, Ruperto N, Aggarwal R, Rider LG, International Myositis Assessment and Clinical Studies Group (IMACS) and Paediatric Rheumatology INternational Trials Organization (PRINTO) (2023)
Performance of the 2016 ACR-EULAR myositis response criteria in juvenile dermatomyositis therapeutic trials and consensus profiles
Rheumatology (Oxford), 62 (11), 3680-3689
DOI 10.1093/rheumatology/kead111, PubMed 36929918

Marstein HS, Witczak BN, Godang K, Olarescu NC, Schwartz T, Flatø B, Molberg Ø, Bollerslev J, Sjaastad I, Sanner H (2023)
Adipokine profile in long-term juvenile dermatomyositis, and associations with adipose tissue distribution and cardiac function: a cross-sectional study
RMD Open, 9 (1)
DOI 10.1136/rmdopen-2022-002815, PubMed 36828644

Marstein HS, Witczak BN, Godang K, Schwartz T, Flatø B, Bollerslev J, Sjaastad I, Sanner H (2023)
Adipose tissue distribution is associated with cardio-metabolic alterations in adult patients with juvenile-onset dermatomyositis
Rheumatology (Oxford), 62 (SI2), SI196-SI204
DOI 10.1093/rheumatology/keac293, PubMed 35575380

Sande NK, Lilleby V, Aga AB, Kirkhus E, Flatø B, Bøyesen P (2023)
Associations between power Doppler ultrasound findings and B-mode synovitis and clinical arthritis in juvenile idiopathic arthritis using a standardised scanning approach and scoring system
RMD Open, 9 (1)
DOI 10.1136/rmdopen-2022-002937, PubMed 36963783

Publications 2022

Bardan I, Fagerli KM, Sexton J, Kvien TK, Bakland G, Mielnik P, Hu Y, Lien G, Flatø B, Molberg Ø, Kristianslund EK, Aga AB (2022)
Treatment Response to Tumor Necrosis Factor Inhibitors and Methotrexate Monotherapy in Adults With Juvenile Idiopathic Arthritis: Data From NOR-DMARD
J Rheumatol, 50 (4), 538-547
DOI 10.3899/jrheum.220645, PubMed 36379571

Li J, Li YR, Glessner JT, Yang J, March ME, Kao C, Vaccaro CN, Bradfield JP, Li J, Mentch FD, Qu HQ, Qi X, Chang X, Hou C, Abrams DJ, Qiu H, Wei Z, Connolly JJ, Wang F, Snyder J, Flatø B, Thompson SD, Langefeld CD, Lie BA, Munro JE et al. (2022)
Identification of Novel Loci Shared by Juvenile Idiopathic Arthritis Subtypes Through Integrative Genetic Analysis
Arthritis Rheumatol, 74 (8), 1420-1429
DOI 10.1002/art.42129, PubMed 35347896

Tollisen A, Selvaag AM, Aasland A, Ingebrigtsen T, Sagen J, Lerdal A, Flatø B (2022)
Personally Generated Quality of Life Outcomes in Adults With Juvenile Idiopathic Arthritis
J Rheumatol, 49 (10), 1138-1145
DOI 10.3899/jrheum.211245, PubMed 35569834

von Brandis E, Jenssen HB, Avenarius DFM, Bjørnerud A, Flatø B, Tomterstad AH, Lilleby V, Rosendahl K, Sakinis T, Zadig PKK, Müller LO (2022)
Automated segmentation of magnetic resonance bone marrow signal: a feasibility study
Pediatr Radiol, 52 (6), 1104-1114
DOI 10.1007/s00247-021-05270-x, PubMed 35107593

von Brandis E, Jenssen HB, Avenarius DFM, Bjørnerud A, Flatø B, Tomterstad AH, Lilleby V, Rosendahl K, Sakinis T, Zadig PKK, Müller LO (2022)
Correction to: Automated segmentation of magnetic resonance bone marrow signal: a feasibility study
Pediatr Radiol, 52 (6), 1196
DOI 10.1007/s00247-022-05315-9, PubMed 35192023

von Brandis E, Zadig PK, Avenarius DFM, Flatø B, Kristian Knudsen P, Lilleby V, Nguyen B, Rosendahl K, Ording Müller LS (2022)
Whole body magnetic resonance imaging in healthy children and adolescents. Bone marrow appearances of the axial skeleton
Eur J Radiol, 154, 110425
DOI 10.1016/j.ejrad.2022.110425, PubMed 35843014

Witczak BN, Bollerslev J, Godang K, Schwartz T, Flatø B, Molberg Ø, Sjaastad I, Sanner H (2022)
Body composition in long-standing juvenile dermatomyositis: associations with disease activity, muscle strength and cardiometabolic measures
Rheumatology (Oxford), 61 (7), 2959-2968
DOI 10.1093/rheumatology/keab805, PubMed 34718443

Witczak BN, Schwartz T, Barth Z, Taraldsrud E, Lund MB, Aaløkken TM, Flatø B, Sjaastad I, Sanner H (2022)
Associations between cardiac and pulmonary involvement in patients with juvenile dermatomyositis-a cross-sectional study
Rheumatol Int, 42 (7), 1213-1220
DOI 10.1007/s00296-021-05071-3, PubMed 34984516

Zadig PK, von Brandis E, Flatø B, Ording Müller LS, Nordal EB, de Horatio LT, Rosendahl K, Avenarius DFM (2022)
Whole body magnetic resonance imaging in healthy children and adolescents: Bone marrow appearances of the appendicular skeleton
Eur J Radiol, 153, 110365
DOI 10.1016/j.ejrad.2022.110365, PubMed 35617871

Publications 2021

Hu Y, Rojahn AE, Flato B (2021)
Multiorgan inflammatory syndrome in children and adolescents after SARS-CoV-2 infection
Tidsskr. Nor. Laegeforen., 141 (14), 1358-1361

Hu Y, Rojahn AE, Flatø B (2021)
[Multisystem inflammatory syndrome in children and adolescents after infection with SARS-CoV-2]
Tidsskr Nor Laegeforen, 141 (2021-14)
DOI 10.4045/tidsskr.20.1040, PubMed 34641663

Marstein HS, Godang K, Flatø B, Sjaastad I, Bollerslev J, Sanner H (2021)
Bone mineral density and explanatory factors in children and adults with juvenile dermatomyositis at long term follow-up; a cross sectional study
Pediatr Rheumatol Online J, 19 (1), 56
DOI 10.1186/s12969-021-00543-z, PubMed 33902632

Sande NK, Bøyesen P, Aga AB, Hammer HB, Flatø B, Roth J, Lilleby V (2021)
Development and reliability of a novel ultrasonographic joint-specific scoring system for synovitis with reference atlas for patients with juvenile idiopathic arthritis
RMD Open, 7 (2)
DOI 10.1136/rmdopen-2021-001581, PubMed 33883255

Tollisen A, Flatø B, Selvaag AM, Aasland A, Ingebrigtsen T, Sagen J, Lerdal A (2021)
Treatment Satisfaction With and Adherence to Disease-Modifying Antirheumatic Drugs in Adult Patients With Juvenile Idiopathic Arthritis
Arthritis Care Res (Hoboken), 73 (2), 221-231
DOI 10.1002/acr.24113, PubMed 31758669

Publications 2020

Berntsen KS, Raastad T, Marstein H, Kirkhus E, Merckoll E, Cumming KT, Flatø B, Sjaastad I, Sanner H (2020)
Functional and Structural Adaptations of Skeletal Muscle in Long-Term Juvenile Dermatomyositis: A Controlled Cross-Sectional Study
Arthritis Rheumatol, 72 (5), 837-848
DOI 10.1002/art.41174, PubMed 31746550

Frid P, Augdal TA, Larheim TA, Halbig J, Rypdal V, Songstad NT, Rosén A, Tylleskär KB, Berstad JR, Flatø B, Stoustrup P, Rosendahl K, Kirkhus E, Nordal E (2020)
Efficacy and safety of intraarticular corticosteroid injections in adolescents with juvenile idiopathic arthritis in the temporomandibular joint: a Norwegian 2-year prospective multicenter pilot study
Pediatr Rheumatol Online J, 18 (1), 75
DOI 10.1186/s12969-020-00464-3, PubMed 32998740

Frid P, Baraniya D, Halbig J, Rypdal V, Songstad NT, Rosèn A, Berstad JR, Flatø B, Alakwaa F, Gil EG, Cetrelli L, Chen T, Al-Hebshi NN, Nordal E, Al-Haroni M (2020)
Salivary Oral Microbiome of Children With Juvenile Idiopathic Arthritis: A Norwegian Cross-Sectional Study
Front Cell Infect Microbiol, 10, 602239
DOI 10.3389/fcimb.2020.602239, PubMed 33251163

Malattia C, Ruperto N, Pederzoli S, Palmisani E, Pistorio A, Wouters C, Dolezalova P, Flato B, Garay S, Giancane G, Wells C, Douglass W, Brunner HI, De Benedetti F, Ravelli A, Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG) (2020)
Tocilizumab may slow radiographic progression in patients with systemic or polyarticular-course juvenile idiopathic arthritis: post hoc radiographic analysis from two randomized controlled trials
Arthritis Res Ther, 22 (1), 211
DOI 10.1186/s13075-020-02303-y, PubMed 32912276

Marstein H, Schwartz T, Aaløkken TM, Lund MB, Flatø B, Sjaastad I, Sanner H (2020)
Novel associations between cytokines and pulmonary involvement in juvenile dermatomyositis - a cross-sectional study of long-term disease
Rheumatology (Oxford), 59 (8), 1862-1870
DOI 10.1093/rheumatology/kez531, PubMed 31740970

Publications 2019

Barth Z, Schwartz T, Flatø B, Aaløkken TM, Koller A, Lund MB, Sjaastad I, Sanner H (2019)
Association Between Nailfold Capillary Density and Pulmonary and Cardiac Involvement in Medium to Longstanding Juvenile Dermatomyositis
Arthritis Care Res (Hoboken), 71 (4), 492-497
DOI 10.1002/acr.23687, PubMed 29953739

Berntsen KS, Edvardsen E, Hansen BH, Flatø B, Sjaastad I, Sanner H (2019)
Cardiorespiratory fitness in long-term juvenile dermatomyositis: a controlled, cross-sectional study of active/inactive disease
Rheumatology (Oxford), 58 (3), 492-501
DOI 10.1093/rheumatology/key342, PubMed 30508195

Consolaro A, Giancane G, Alongi A, van Dijkhuizen EHP, Aggarwal A, Al-Mayouf SM, Bovis F, De Inocencio J, Demirkaya E, Flato B, Foell D, Garay SM, Lazăr C, Lovell DJ, Montobbio C, Miettunen P, Mihaylova D, Nielsen S, Orban I, Rumba-Rozenfelde I, Magalhães CS, Shafaie N, Susic G, Trachana M, Wulffraat N et al. (2019)
Phenotypic variability and disparities in treatment and outcomes of childhood arthritis throughout the world: an observational cohort study
Lancet Child Adolesc Health, 3 (4), 255-263
DOI 10.1016/S2352-4642(19)30027-6, PubMed 30819662

Tollisen A, Selvaag AM, Aasland A, Lerdal A, Flatø B (2019)
Longitudinal Health Status from Early Disease to Adulthood and Associated Prognostic Factors in Juvenile Idiopathic Arthritis
J Rheumatol, 46 (10), 1335-1344
DOI 10.3899/jrheum.180948, PubMed 30877211

Witczak BN, Hetlevik SO, Sanner H, Barth Z, Schwartz T, Flatø B, Lilleby V, Sjaastad I (2019)
Effect on Cardiac Function of Longstanding Juvenile-onset Mixed Connective Tissue Disease: A Controlled Study
J Rheumatol, 46 (7), 739-747
DOI 10.3899/jrheum.180526, PubMed 30877222

Publications 2018

Aulie HA, Estensen ME, Selvaag AM, Lilleby V, Flatø B, Aakhus S (2018)
Arterial properties in adults with long-lasting active juvenile idiopathic arthritis compared to healthy controls
Pediatr Rheumatol Online J, 16 (1), 85
DOI 10.1186/s12969-018-0302-5, PubMed 30594204

Barth Z, Witczak BN, Flatø B, Koller A, Sjaastad I, Sanner H (2018)
Assessment of Microvascular Abnormalities by Nailfold Capillaroscopy in Juvenile Dermatomyositis After Medium- to Long-Term Followup
Arthritis Care Res (Hoboken), 70 (5), 768-776
DOI 10.1002/acr.23338, PubMed 28805016

Flato B, Rygg M, Nordal EB, Røisland M, Ødegård HB, Hoftun GB, Songstad NT, Consolaro A, Bovis F, Ruperto N, Paediatric Rheumatology International Trials Organisation (PRINTO) (2018)
The Norwegian version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR)
Rheumatol Int, 38 (Suppl 1), 291-298
DOI 10.1007/s00296-018-3963-y, PubMed 29637327

Hetlevik SO, Flatø B, Aaløkken TM, Lund MB, Reiseter S, Mynarek GK, Nordal E, Rygg M, Lilleby V (2018)
Pulmonary Manifestations and Progression of Lung Disease in Juvenile-onset Mixed Connective Tissue Disease
J Rheumatol, 46 (1), 93-100
DOI 10.3899/jrheum.180019, PubMed 30068767

Tollisen A, Selvaag AM, Aulie HA, Lilleby V, Aasland A, Lerdal A, Flatø B (2018)
Physical Functioning, Pain, and Health-Related Quality of Life in Adults With Juvenile Idiopathic Arthritis: A Longitudinal 30-Year Followup Study
Arthritis Care Res (Hoboken), 70 (5), 741-749
DOI 10.1002/acr.23327, PubMed 28732134

Publications 2017

Augestad L, Hammarstrom C, Flato B, Bjerre A (2017)
Renal failure of systemic vasculitis in children
Tidsskr. Nor. Laegeforen., 137 (19), 1507-1511

Augestad L, Hammarström C, Flatø B, Bjerre A (2017)
Renal involvement in paediatric systemic vasculitis
Tidsskr Nor Laegeforen, 137 (19)
DOI 10.4045/tidsskr.16.0592, PubMed 29043736

Berntsen KS, Tollisen A, Schwartz T, Kirkhus E, Aaløkken TM, Lund MB, Flatø B, Sjaastad I, Sanner H (2017)
Submaximal Exercise Capacity in Juvenile Dermatomyositis after Longterm Disease: The Contribution of Muscle, Lung, and Heart Involvement
J Rheumatol, 44 (6), 827-834
DOI 10.3899/jrheum.160997, PubMed 28365577

Frid P, Nordal E, Bovis F, Giancane G, Larheim TA, Rygg M, Pires Marafon D, De Angelis D, Palmisani E, Murray KJ, Oliveira S, Simonini G, Corona F, Davidson J, Foster H, Steenks MH, Flato B, Zulian F, Baildam E, Saurenmann RK, Lahdenne P, Ravelli A, Martini A, Pistorio A, Ruperto N et al. (2017)
Temporomandibular Joint Involvement in Association With Quality of Life, Disability, and High Disease Activity in Juvenile Idiopathic Arthritis
Arthritis Care Res (Hoboken), 69 (5), 677-686
DOI 10.1002/acr.23003, PubMed 27564918

Selvaag AM, Kirkhus E, Törnqvist L, Lilleby V, Aulie HA, Flatø B (2017)
Radiographic damage in hands and wrists of patients with juvenile idiopathic arthritis after 29 years of disease duration
Pediatr Rheumatol Online J, 15 (1), 20
DOI 10.1186/s12969-017-0151-7, PubMed 28399930

Publications 2016

Anderson JH, Anderson KR, Aulie HA, Crowson CS, Mason TG, Ardoin SP, Reed AM, Flatø B (2016)
Juvenile idiopathic arthritis and future risk for cardiovascular disease: a multicenter study
Scand J Rheumatol, 45 (4), 299-303
DOI 10.3109/03009742.2015.1126345, PubMed 26854592

Constantin T, Foeldvari I, Vojinovic J, Horneff G, Burgos-Vargas R, Nikishina I, Akikusa JD, Avcin T, Chaitow J, Koskova E, Lauwerys BR, Calvo Penades I, Flato B, Gamir ML, Huppertz HI, Jaller Raad JJ, Jarosova K, Anton J, Macku M, Otero Escalante WJ, Rutkowska-Sak L, Trauzeddel R, Velez-Sanchez PJ, Wouters C, Wajdula J et al. (2016)
Two-year Efficacy and Safety of Etanercept in Pediatric Patients with Extended Oligoarthritis, Enthesitis-related Arthritis, or Psoriatic Arthritis
J Rheumatol, 43 (4), 816-24
DOI 10.3899/jrheum.150430, PubMed 26932344

Evensen K, Aulie HA, Rønning OM, Flatø B, Russell D (2016)
Carotid Atherosclerosis in Adult Patients with Persistently Active Juvenile Idiopathic Arthritis Compared with Healthy Controls
J Rheumatol, 43 (4), 810-5
DOI 10.3899/jrheum.150499, PubMed 26879363

Finkel TH, Li J, Wei Z, Wang W, Zhang H, Behrens EM, Reuschel EL, Limou S, Wise C, Punaro M, Becker ML, Munro JE, Flatø B, Førre Ø, Thompson SD, Langefeld CD, Glass DN, Glessner JT, Kim CE, Frackelton E, Shivers DK, Thomas KA, Chiavacci RM, Hou C, Xu K et al. (2016)
Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility
BMC Med Genet, 17, 24
DOI 10.1186/s12881-016-0285-3, PubMed 27005825

Hetlevik SO, Flatø B, Rygg M, Nordal EB, Brunborg C, Hetland H, Lilleby V (2016)
Long-term outcome in juvenile-onset mixed connective tissue disease: a nationwide Norwegian study
Ann Rheum Dis, 76 (1), 159-165
DOI 10.1136/annrheumdis-2016-209522, PubMed 27283334

Kirkhus E, Gunderson RB, Smith HJ, Flatø B, Hetlevik SO, Larheim TA, Arvidsson LZ (2016)
Temporomandibular joint involvement in childhood arthritis: comparison of ultrasonography-assessed capsular width and MRI-assessed synovitis
Dentomaxillofac Radiol, 45 (8), 20160195
DOI 10.1259/dmfr.20160195, PubMed 27383060

Stray-Pedersen A, Sorte HS, Samarakoon P, Gambin T, Chinn IK, Coban Akdemir ZH, Erichsen HC, Forbes LR, Gu S, Yuan B, Jhangiani SN, Muzny DM, Rødningen OK, Sheng Y, Nicholas SK, Noroski LM, Seeborg FO, Davis CM, Canter DL, Mace EM, Vece TJ, Allen CE, Abhyankar HA, Boone PM, Beck CR et al. (2016)
Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders
J Allergy Clin Immunol, 139 (1), 232-245
DOI 10.1016/j.jaci.2016.05.042, PubMed 27577878

Publications 2015

Aulie HA, Estensen ME, Selvaag AM, Lilleby V, Murbraech K, Flatø B, Aakhus S (2015)
Cardiac Function in Adult Patients with Juvenile Idiopathic Arthritis
J Rheumatol, 42 (9), 1716-23
DOI 10.3899/jrheum.141351, PubMed 26178287

Barth Z, Nomeland Witczak B, Schwartz T, Gjesdal K, Flatø B, Koller A, Sanner H, Sjaastad I (2015)
In juvenile dermatomyositis, heart rate variability is reduced, and associated with both cardiac dysfunction and markers of inflammation: a cross-sectional study median 13.5 years after symptom onset
Rheumatology (Oxford), 55 (3), 535-43
DOI 10.1093/rheumatology/kev376, PubMed 26500284

Chiaroni-Clarke RC, Li YR, Munro JE, Chavez RA, Scurrah KJ, Pezic A, Akikusa JD, Allen RC, Piper SE, Becker ML, Thompson SD, Lie BA, Flato B, Forre O, Punaro M, Wise C, Saffery R, Finkel TH, Hakonarson H, Ponsonby AL, Ellis JA (2015)
The association of PTPN22 rs2476601 with juvenile idiopathic arthritis is specific to females
Genes Immun, 16 (7), 495-8
DOI 10.1038/gene.2015.32, PubMed 26291515

Johnsson A, Flatø B, Knudsen PK, Lilleby V (2015)
Clinical outcome in a Norwegian cohort of patients with chronic recurrent multifocal osteomyelitis
Scand J Rheumatol, 44 (6), 513-4
DOI 10.3109/03009742.2015.1055514, PubMed 26312400

Kirkhus E, Arvidsson LZ, Smith HJ, Flatø B, Hetlevik SO, Larheim TA (2015)
Disk abnormality coexists with any degree of synovial and osseous abnormality in the temporomandibular joints of children with juvenile idiopathic arthritis
Pediatr Radiol, 46 (3), 331-41
DOI 10.1007/s00247-015-3493-7, PubMed 26637998

Li YR, Li J, Zhao SD, Bradfield JP, Mentch FD, Maggadottir SM, Hou C, Abrams DJ, Chang D, Gao F, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, Glessner JT, Li D, Kao C, Thomas KA, Qiu H, Chiavacci RM, Kim CE, Wang F, Snyder J, Richie MD et al. (2015)
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases
Nat Med, 21 (9), 1018-27
DOI 10.1038/nm.3933, PubMed 26301688

Li YR, Zhao SD, Li J, Bradfield JP, Mohebnasab M, Steel L, Kobie J, Abrams DJ, Mentch FD, Glessner JT, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, Li D, Maggadottir SM, Thomas KA, Qui H, Chiavacci RM, Kim CE, Wang F, Snyder J, Flatø B, Førre Ø et al. (2015)
Genetic sharing and heritability of paediatric age of onset autoimmune diseases
Nat Commun, 6, 8442
DOI 10.1038/ncomms9442, PubMed 26450413

Ruperto N, Pistorio A, Oliveira S, Zulian F, Cuttica R, Ravelli A, Fischbach M, Magnusson B, Sterba G, Avcin T, Brochard K, Corona F, Dressler F, Gerloni V, Apaz MT, Bracaglia C, Cespedes-Cruz A, Cimaz R, Couillault G, Joos R, Quartier P, Russo R, Tardieu M, Wulffraat N, Bica B et al. (2015)
Prednisone versus prednisone plus ciclosporin versus prednisone plus methotrexate in new-onset juvenile dermatomyositis: a randomised trial
Lancet, 387 (10019), 671-678
DOI 10.1016/S0140-6736(15)01021-1, PubMed 26645190

Publications 2014

Aulie HA, Selvaag AM, Günther A, Lilleby V, Molberg Ø, Hartmann A, Holdaas H, Flatø B (2014)
Arterial haemodynamics and coronary artery calcification in adult patients with juvenile idiopathic arthritis
Ann Rheum Dis, 74 (8), 1515-21
DOI 10.1136/annrheumdis-2013-204804, PubMed 24695010

Ellis JA, Scurrah KJ, Li YR, Ponsonby AL, Chavez RA, Pezic A, Dwyer T, Akikusa JD, Allen RC, Becker ML, Thompson SD, Lie BA, Flatø B, Førre O, Punaro M, Wise C, Finkel TH, Hakonarson H, Munro JE (2014)
Epistasis amongst PTPN2 and genes of the vitamin D pathway contributes to risk of juvenile idiopathic arthritis
J Steroid Biochem Mol Biol, 145, 113-20
DOI 10.1016/j.jsbmb.2014.10.012, PubMed 25460303

Lilleby V, Haydon J, Sanner H, Krossness BK, Ringstad G, Flatø B (2014)
Severe macrophage activation syndrome and central nervous system involvement in juvenile dermatomyositis
Scand J Rheumatol, 43 (2), 171-3
DOI 10.3109/03009742.2013.863968, PubMed 24588361

Sanner H, Schwartz T, Flatø B, Vistnes M, Christensen G, Sjaastad I (2014)
Increased levels of eotaxin and MCP-1 in juvenile dermatomyositis median 16.8 years after disease onset; associations with disease activity, duration and organ damage
PLoS One, 9 (3), e92171
DOI 10.1371/journal.pone.0092171, PubMed 24647150

Sanner H, Sjaastad I, Flatø B (2014)
Disease activity and prognostic factors in juvenile dermatomyositis: a long-term follow-up study applying the Paediatric Rheumatology International Trials Organization criteria for inactive disease and the myositis disease activity assessment tool
Rheumatology (Oxford), 53 (9), 1578-85
DOI 10.1093/rheumatology/keu146, PubMed 24692575

Schwartz T, Sjaastad I, Flatø B, Vistnes M, Christensen G, Sanner H (2014)
In active juvenile dermatomyositis, elevated eotaxin and MCP-1 and cholesterol levels in the upper normal range are associated with cardiac dysfunction
Rheumatology (Oxford), 53 (12), 2214-22
DOI 10.1093/rheumatology/keu256, PubMed 24996906

Selvaag AM, Aulie HA, Lilleby V, Flatø B (2014)
Disease progression into adulthood and predictors of long-term active disease in juvenile idiopathic arthritis
Ann Rheum Dis, 75 (1), 190-5
DOI 10.1136/annrheumdis-2014-206034, PubMed 25362042

Publications 2013

Schwartz T, Sanner H, Gjesdal O, Flatø B, Sjaastad I (2013)
In juvenile dermatomyositis, cardiac systolic dysfunction is present after long-term follow-up and is predicted by sustained early skin activity
Ann Rheum Dis, 73 (10), 1805-10
DOI 10.1136/annrheumdis-2013-203279, PubMed 23881732

Publications 2012

Eike MC, Skinningsrud B, Ronninger M, Stormyr A, Kvien TK, Joner G, Njølstad PR, Førre O, Flatø B, Alfredsson L, Padyukov L, Undlien DE, Lie BA (2012)
CIITA gene variants are associated with rheumatoid arthritis in Scandinavian populations
Genes Immun, 13 (5), 431-6
DOI 10.1038/gene.2012.11, PubMed 22513452

Ruperto N, Brunner HI, Quartier P, Constantin T, Wulffraat N, Horneff G, Brik R, McCann L, Kasapcopur O, Rutkowska-Sak L, Schneider R, Berkun Y, Calvo I, Erguven M, Goffin L, Hofer M, Kallinich T, Oliveira SK, Uziel Y, Viola S, Nistala K, Wouters C, Cimaz R, Ferrandiz MA, Flato B et al. (2012)
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis
N Engl J Med, 367 (25), 2396-406
DOI 10.1056/NEJMoa1205099, PubMed 23252526

Tollisen A, Sanner H, Flatø B, Wahl AK (2012)
Quality of life in adults with juvenile-onset dermatomyositis: a case-control study
Arthritis Care Res (Hoboken), 64 (7), 1020-7
DOI 10.1002/acr.21637, PubMed 22328537

Publications 2011

Nordang GB, Viken MK, Amundsen SS, Sanchez ES, Flatø B, Førre OT, Martin J, Kvien TK, Lie BA (2011)
Interferon regulatory factor 5 gene polymorphism confers risk to several rheumatic diseases and correlates with expression of alternative thymic transcripts
Rheumatology (Oxford), 51 (4), 619-26
DOI 10.1093/rheumatology/ker364, PubMed 22179739

Schwartz T, Sanner H, Husebye T, Flatø B, Sjaastad I (2011)
Cardiac dysfunction in juvenile dermatomyositis: a case-control study
Ann Rheum Dis, 70 (5), 766-71
DOI 10.1136/ard.2010.137968, PubMed 21216816

Staalesen Strumse YA, Nordvåg BY, Stanghelle JK, Røisland M, Winther A, Pajunen PA, Garen T, Flatø B (2011)
Efficacy of rehabilitation for patients with ankylosing spondylitis: comparison of a four-week rehabilitation programme in a Mediterranean and a Norwegian setting
J Rehabil Med, 43 (6), 534-42
DOI 10.2340/16501977-0804, PubMed 21491073

Publications 2010

Arvidsson LZ, Fjeld MG, Smith HJ, Flatø B, Ogaard B, Larheim TA (2010)
Craniofacial growth disturbance is related to temporomandibular joint abnormality in patients with juvenile idiopathic arthritis, but normal facial profile was also found at the 27-year follow-up
Scand J Rheumatol, 39 (5), 373-9
DOI 10.3109/03009741003685624, PubMed 20615158

Arvidsson LZ, Smith HJ, Flatø B, Larheim TA (2010)
Temporomandibular joint findings in adults with long-standing juvenile idiopathic arthritis: CT and MR imaging assessment
Radiology, 256 (1), 191-200
DOI 10.1148/radiol.10091810, PubMed 20574096

Fjeld M, Arvidsson L, Smith HJ, Flatø B, Ogaard B, Larheim T (2010)
Relationship between disease course in the temporomandibular joints and mandibular growth rotation in patients with juvenile idiopathic arthritis followed from childhood to adulthood
Pediatr Rheumatol Online J, 8, 13
DOI 10.1186/1546-0096-8-13, PubMed 20412568

Kirkhus E, Flatø B, Riise O, Reiseter T, Smith HJ (2010)
Differences in MRI findings between subgroups of recent-onset childhood arthritis
Pediatr Radiol, 41 (4), 432-40
DOI 10.1007/s00247-010-1897-y, PubMed 21136049

Lien G, Ueland T, Godang K, Selvaag AM, Førre OT, Flatø B (2010)
Serum levels of osteoprotegerin and receptor activator of nuclear factor -κB ligand in children with early juvenile idiopathic arthritis: a 2-year prospective controlled study
Pediatr Rheumatol Online J, 8, 30
DOI 10.1186/1546-0096-8-30, PubMed 21134287

Ostile IL, Johansson I, Aasland A, Flatö B, Möller A (2010)
Self-rated physical and psychosocial health in a cohort of young adults with juvenile idiopathic arthritis
Scand J Rheumatol, 39 (4), 318-25
DOI 10.3109/03009740903505213, PubMed 20476866

Ruperto N, Pistorio A, Ravelli A, Rider LG, Pilkington C, Oliveira S, Wulffraat N, Espada G, Garay S, Cuttica R, Hofer M, Quartier P, Melo-Gomes J, Reed AM, Wierzbowska M, Feldman BM, Harjacek M, Huppertz HI, Nielsen S, Flato B, Lahdenne P, Michels H, Murray KJ, Punaro L, Rennebohm R et al. (2010)
The Paediatric Rheumatology International Trials Organisation provisional criteria for the evaluation of response to therapy in juvenile dermatomyositis
Arthritis Care Res (Hoboken), 62 (11), 1533-41
DOI 10.1002/acr.20280, PubMed 20583105

Sanner H, Kirkhus E, Merckoll E, Tollisen A, Røisland M, Lie BA, Taraldsrud E, Gran JT, Flatø B (2010)
Long-term muscular outcome and predisposing and prognostic factors in juvenile dermatomyositis: A case-control study
Arthritis Care Res (Hoboken), 62 (8), 1103-11
DOI 10.1002/acr.20203, PubMed 20506141

Sanner H, Aaløkken TM, Gran JT, Sjaastad I, Johansen B, Flatø B (2010)
Pulmonary outcome in juvenile dermatomyositis: a case-control study
Ann Rheum Dis, 70 (1), 86-91
DOI 10.1136/ard.2010.131433, PubMed 20805295

Publications 2009

Arvidsson LZ, Flatø B, Larheim TA (2009)
Radiographic TMJ abnormalities in patients with juvenile idiopathic arthritis followed for 27 years
Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 108 (1), 114-23
DOI 10.1016/j.tripleo.2009.03.012, PubMed 19540449

Flatø B, Lien G, Smerdel-Ramoya A, Vinje O (2009)
Juvenile psoriatic arthritis: longterm outcome and differentiation from other subtypes of juvenile idiopathic arthritis
J Rheumatol, 36 (3), 642-50
DOI 10.3899/jrheum.080543, PubMed 19208605

Ostlie IL, Aasland A, Johansson I, Flatö B, Möller A (2009)
A longitudinal follow-up study of physical and psychosocial health in young adults with chronic childhood arthritis
Clin Exp Rheumatol, 27 (6), 1039-46
PubMed 20149328

Sanner H, Gran JT, Sjaastad I, Flatø B (2009)
Cumulative organ damage and prognostic factors in juvenile dermatomyositis: a cross-sectional study median 16.8 years after symptom onset
Rheumatology (Oxford), 48 (12), 1541-7
DOI 10.1093/rheumatology/kep302, PubMed 19776224

Skinningsrud B, Lie BA, Husebye ES, Kvien TK, Førre Ø, Flatø B, Stormyr A, Joner G, Njølstad PR, Egeland T, Undlien DE (2009)
A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis
Ann Rheum Dis, 69 (8), 1471-4
DOI 10.1136/ard.2009.114934, PubMed 19734133

Staalesen Strumse YA, Nordvag BY, Stanghelle JK, Røsland M, Winther A, Pajunen PA, Garen T, Flatø B (2009)
The efficacy of rehabilitation for patients with rheumatoid arthritis: comparison between a 4-week rehabilitation programme in a warm and cold climate
Scand J Rheumatol, 38 (1), 28-37
DOI 10.1080/03009740802304549, PubMed 18728936

Publications 2008

Dolman KM, Brouwer N, Frakking FN, Flatø B, Tak PP, Kuijpers TW, Førre O, Smerdel-Ramoya A (2008)
Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study
Arthritis Res Ther, 10 (2), R32
DOI 10.1186/ar2386, PubMed 18334024

Riise ØR, Handeland KS, Cvancarova M, Wathne KO, Nakstad B, Abrahamsen TG, Kirkhus E, Flatø B (2008)
Incidence and characteristics of arthritis in Norwegian children: a population-based study
Pediatrics, 121 (2), e299-306
DOI 10.1542/peds.2007-0291, PubMed 18227193

Riise ØR, Kirkhus E, Handeland KS, Flatø B, Reiseter T, Cvancarova M, Nakstad B, Wathne KO (2008)
Childhood osteomyelitis-incidence and differentiation from other acute onset musculoskeletal features in a population-based study
BMC Pediatr, 8, 45
DOI 10.1186/1471-2431-8-45, PubMed 18937840

Riise ØR, Lee A, Cvancarova M, Handeland KS, Wathne KO, Nakstad B, Gaustad P, Flatø B (2008)
Recent-onset childhood arthritis--association with Streptococcus pyogenes in a population-based study
Rheumatology (Oxford), 47 (7), 1006-11
DOI 10.1093/rheumatology/ken122, PubMed 18420659

Publications 2007

Eike MC, Nordang GB, Karlsen TH, Boberg KM, Vatn MH, IBSEN study group, Dahl-Jørgensen K, Rønningen KS, Joner G, Flatø B, Bergquist A, Thorsby E, Førre O, Kvien TK, Undlien DE, Lie BA (2007)
The FCRL3 -169T>C polymorphism is associated with rheumatoid arthritis and shows suggestive evidence of involvement with juvenile idiopathic arthritis in a Scandinavian panel of autoimmune diseases
Ann Rheum Dis, 67 (9), 1287-91
DOI 10.1136/ard.2007.077826, PubMed 18065500

Lindner E, Nordang GB, Melum E, Flatø B, Selvaag AM, Thorsby E, Kvien TK, Førre OT, Lie BA (2007)
Lack of association between the chemokine receptor 5 polymorphism CCR5delta32 in rheumatoid arthritis and juvenile idiopathic arthritis
BMC Med Genet, 8, 33
DOI 10.1186/1471-2350-8-33, PubMed 17565662

Viken MK, Sollid HD, Joner G, Dahl-Jørgensen K, Rønningen KS, Undlien DE, Flatø B, Selvaag AM, Førre Ø, Kvien TK, Thorsby E, Melms A, Tolosa E, Lie BA (2007)
Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis
Hum Immunol, 68 (9), 748-55
DOI 10.1016/j.humimm.2007.05.009, PubMed 17869649

Publications 2006

Flatø B, Hoffmann-Vold AM, Reiff A, Førre Ø, Lien G, Vinje O (2006)
Long-term outcome and prognostic factors in enthesitis-related arthritis: a case-control study
Arthritis Rheum, 54 (11), 3573-82
DOI 10.1002/art.22181, PubMed 17075863

Gutiérrez-Suárez R, Pistorio A, Cespedes Cruz A, Norambuena X, Flato B, Rumba I, Harjacek M, Nielsen S, Susic G, Mihaylova D, Huemer C, Melo-Gomes J, Andersson-Gare B, Balogh Z, De Cunto C, Vesely R, Pagava K, Romicka AM, Burgos-Vargas R, Martini A, Ruperto N, Pediatric Rheumatology International Trials Organisation (PRINTO) (2006)
Health-related quality of life of patients with juvenile idiopathic arthritis coming from 3 different geographic areas. The PRINTO multinational quality of life cohort study
Rheumatology (Oxford), 46 (2), 314-20
DOI 10.1093/rheumatology/kel218, PubMed 16877459

Reikvam A, Hexeberg S, Kvien TK, Slørdal L, Aabakken L, Engebretsen L, Flatø B, Idsø N, Johnsen V, Kalstad S, Madsen S, Mikkelsen K, Os I, REder J (2006)
[Clinical use of COX inhibitors--a consensus]
Tidsskr Nor Laegeforen, 126 (5), 591-5
PubMed 16505867

Selvaag AM, Flatø B, Dale K, Lien G, Vinje O, Smerdel-Ramoya A, Førre Ø (2006)
Radiographic and clinical outcome in early juvenile rheumatoid arthritis and juvenile spondyloarthropathy: a 3-year prospective study
J Rheumatol, 33 (7), 1382-91
PubMed 16758503

Publications 2005

Lien G, Selvaag AM, Flatø B, Haugen M, Vinje O, Sørskaar D, Dale K, Egeland T, Førre Ø (2005)
A two-year prospective controlled study of bone mass and bone turnover in children with early juvenile idiopathic arthritis
Arthritis Rheum, 52 (3), 833-40
DOI 10.1002/art.20963, PubMed 15751052

Lilleby V, Flatø B, Førre O (2005)
Disease duration, hypertension and medication requirements are associated with organ damage in childhood-onset systemic lupus erythematosus
Clin Exp Rheumatol, 23 (2), 261-9
PubMed 15895902

Lilleby V, Lien G, Frey Frøslie K, Haugen M, Flatø B, Førre Ø (2005)
Frequency of osteopenia in children and young adults with childhood-onset systemic lupus erythematosus
Arthritis Rheum, 52 (7), 2051-9
DOI 10.1002/art.21115, PubMed 15986346

Ruperto N, Garcia-Munitis P, Villa L, Pesce M, Aggarwal A, Fasth A, Avcin T, Bae SC, Balogh Z, Li C, De Inocencio J, Dibra M, Dolezalova P, El Miedany Y, Flato B, Harjacek M, Huppertz HI, Kanakoudi-Tsakalidou F, Wulffraat N, Lahdenne P, Melo-Gomes JA, Mihaylova D, Nielsen S, Nikishina I, Ozdogan H et al. (2005)
PRINTO/PRES international website for families of children with rheumatic diseases: www.pediatric-rheumatology.printo.it
Ann Rheum Dis, 64 (7), 1101-6
DOI 10.1136/ard.2004.030221, PubMed 15760930

Selvaag AM, Lien G, Sørskaar D, Vinje O, Førre Ø, Flatø B (2005)
Early disease course and predictors of disability in juvenile rheumatoid arthritis and juvenile spondyloarthropathy: a 3 year prospective study
J Rheumatol, 32 (6), 1122-30
PubMed 15940778

Publications 2004

Smerdel A, Dai KZ, Lorentzen AR, Flatø B, Maslinski S, Thorsby E, Førre Ø, Spurkland A (2004)
Genetic association between juvenile rheumatoid arthritis and polymorphism in the SH2D2A gene
Genes Immun, 5 (4), 310-2
DOI 10.1038/sj.gene.6364093, PubMed 15129233

Publications 2003

Flatø B, Lien G, Smerdel A, Vinje O, Dale K, Johnston V, Sørskaar D, Moum T, Ploski R, Førre Ø (2003)
Prognostic factors in juvenile rheumatoid arthritis: a case-control study revealing early predictors and outcome after 14.9 years
J Rheumatol, 30 (2), 386-93
PubMed 12563700

Lien G, Flatø B, Haugen M, Vinje O, Sørskaar D, Dale K, Johnston V, Egeland T, Førre Ø (2003)
Frequency of osteopenia in adolescents with early-onset juvenile idiopathic arthritis: a long-term outcome study of one hundred five patients
Arthritis Rheum, 48 (8), 2214-23
DOI 10.1002/art.11097, PubMed 12905475

Selvaag AM, Flatø B, Lien G, Sørskaar D, Vinje O, Førre Ø (2003)
Measuring health status in early juvenile idiopathic arthritis: determinants and responsiveness of the child health questionnaire
J Rheumatol, 30 (7), 1602-10
PubMed 12858465

Publications 2002

Flatø B, Smerdel A, Johnston V, Lien G, Dale K, Vinje O, Egeland T, Sørskaar D, Førre Ø (2002)
The influence of patient characteristics, disease variables, and HLA alleles on the development of radiographically evident sacroiliitis in juvenile idiopathic arthritis
Arthritis Rheum, 46 (4), 986-94
DOI 10.1002/art.10146, PubMed 11953976

Haugen MA, Lien G, Flatø B, Kvammen JA, Vinje O, Sørskaar D, Førre Ø (2002)
Minor impact of juvenile arthritis on nutritional status in young adult patients
Arthritis Rheum, 47 (6), 623-9
DOI 10.1002/art.10799, PubMed 12522836

Smerdel A, Ploski R, Flatø B, Musiej-Nowakowska E, Thorsby E, Førre Ø (2002)
Juvenile idiopathic arthritis (JIA) is primarily associated with HLA-DR8 but not DQ4 on the DR8-DQ4 haplotype
Ann Rheum Dis, 61 (4), 354-7
DOI 10.1136/ard.61.4.354, PubMed 11874841

Publications 2001

Selvaag AM, Ruperto N, Asplin L, Rygg M, Landgraf JM, Forre Ø, Flatø B, Paediatric Rheumatology International Trials Organisation (2001)
The Norwegian version of the Childhood Health Assessment Questionnaire (CHAQ) and the Child Health Questionnaire (CHQ)
Clin Exp Rheumatol, 19 (4 Suppl 23), S116-20
PubMed 11510313

Publications 2000

Haugen M, Lien G, Flatø B, Kvammen J, Vinje O, Sørskaar D, Førre O (2000)
Young adults with juvenile arthritis in remission attain normal peak bone mass at the lumbar spine and forearm
Arthritis Rheum, 43 (7), 1504-10
DOI 10.1002/1529-0131(200007)43:7<1504::AID-ANR13>3.0.CO;2-0, PubMed 10902752

Vinje O, Flatø B, Førre O (2000)
[Classification of idiopathic juvenile arthritis]
Tidsskr Nor Laegeforen, 120 (4), 459-65
PubMed 10833937

Publications 1999

Flatø B (1999)
Outcome and predictive factors in juvenile arthritis and allied disorders
Center for Rheumatic Diseases, The National Hospital, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 990567079, ISBN 82-7722-097-9

Publications 1998

Flatø B, Sørskaar D, Vinje O, Lien G, Aasland A, Moum T, Førre O (1998)
Measuring disability in early juvenile rheumatoid arthritis: evaluation of a Norwegian version of the childhood Health Assessment Questionnaire
J Rheumatol, 25 (9), 1851-8
PubMed 9733471

Flatø B, Vinje O, Førre O (1998)
Toxicity of antirheumatic and anti-inflammatory drugs in children
Clin Rheumatol, 17 (6), 505-10
DOI 10.1007/BF01451288, PubMed 9890680

Flatø B, Aasland A, Vinje O, Førre O (1998)
Outcome and predictive factors in juvenile rheumatoid arthritis and juvenile spondyloarthropathy
J Rheumatol, 25 (2), 366-75
PubMed 9489836

Aasland A, Flatø B, Vandvik IH (1998)
Patient and parent experiences with health care services in pediatric rheumatology
Scand J Rheumatol, 27 (4), 265-72
DOI 10.1080/030097498442370, PubMed 9751466

Publications 1997

Flatø B, Aasland A, Vandvik IH, Førre O (1997)
Outcome and predictive factors in children with chronic idiopathic musculoskeletal pain
Clin Exp Rheumatol, 15 (5), 569-77
PubMed 9307867

Aasland A, Flatö B, Vandvik IH (1997)
Psychosocial factors in children with idiopathic musculoskeletal pain: a prospective, longitudinal study
Acta Paediatr, 86 (7), 740-6
DOI 10.1111/j.1651-2227.1997.tb08578.x, PubMed 9240883

Aasland A, Flatø B, Vandvik IH (1997)
Psychosocial outcome in juvenile chronic arthritis: a nine-year follow-up
Clin Exp Rheumatol, 15 (5), 561-8
PubMed 9307866

Publications 1995

Albertioni F, Flatø B, Seideman P, Beck O, Vinje O, Peterson C, Eksborg S (1995)
Methotrexate in juvenile rheumatoid arthritis. Evidence of age dependent pharmacokinetics
Eur J Clin Pharmacol, 47 (6), 507-11
DOI 10.1007/BF00193703, PubMed 7768253

Ploski R, Flatø B, Vinje O, Maksymowych W, Førre O, Thorsby E (1995)
Association to HLA-DRB1*08, HLA-DPB1*0301 and homozygosity for an HLA-linked proteasome gene in juvenile ankylosing spondylitis
Hum Immunol, 44 (2), 88-96
DOI 10.1016/0198-8859(95)00063-a, PubMed 8847233

Ploski R, McDowell TL, Symons JA, Flatø B, Duff GW, Thorsby E, Førre O (1995)
Interaction between HLA-DR and HLA-DP, and between HLA and interleukin 1 alpha in juvenile rheumatoid arthritis indicates heterogeneity of pathogenic mechanisms of the disease
Hum Immunol, 42 (4), 343-7
DOI 10.1016/0198-8859(94)00098-b, PubMed 7558921

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