Publications by Tor Paaske Utheim

290 publications found

  1. Chang K, Wu JG, Ma TL, Hsu SH, Cho KS, Yu Z, Lennikov A, Ashok A, Rajagopalan A, Chen MH, Su WF, Utheim TP, Chen DF (2024)
    Bioengineering Strategy to Promote CNS Nerve Growth and Regeneration via Chronic Glutamate Signaling
    Acta Biomater (in press)
    DOI 10.1016/j.actbio.2024.10.023, PubMed 39427766
  2. Utheim TP, Chen X, Fineide F, Steinkjer T, Heegaard S, Kolko M, Dartt DA, Khan AZ (2024)
    Response predictors of a topical corticosteroid-based regimen for dry eyes: A real-life study
    Acta Ophthalmol (in press)
    DOI 10.1111/aos.16758, PubMed 39344883
  3. Naqvi M, Utheim TP, Charnock C (2024)
    Whole genome sequencing and characterization of Corynebacterium isolated from the healthy and dry eye ocular surface
    BMC Microbiol, 24 (1), 368
    DOI 10.1186/s12866-024-03517-9, PubMed 39342108
  4. Mysen OMB, Hynnekleiv L, Magnø MS, Vehof J, Utheim TP (2024)
    Review of Hydroxypropyl Methylcellulose in Artificial Tears for the Treatment of Dry Eye Disease
    Acta Ophthalmol (in press)
    DOI 10.1111/aos.16753, PubMed 39219040
  5. Gunes K, Chang K, Lennikov A, Tai WL, Chen J, ElZaridi F, Cho KS, Utheim TP, Dong Feng C (2024)
    Preservation of vision by transpalpebral electrical stimulation in mice with inherited retinal degeneration
    Front Cell Dev Biol, 12, 1412909
    DOI 10.3389/fcell.2024.1412909, PubMed 39206091
  6. Markholm CE, Overskott HL, Sehic A, Utheim TP, Khan Q (2024)
    Integrating Structured Digital Tools with the Traditional Hands-on Puzzle Method for Teaching Tooth Morphology: A Comparative Study of Educational Outcomes
    Dent J (Basel), 12 (8)
    DOI 10.3390/dj12080270, PubMed 39195114
  7. Fjaervoll HK, Fjaervoll KA, Yang M, Reiten OK, Bair J, Lee C, Utheim TP, Dartt D (2024)
    Purinergic agonists increase [Ca2+]i in rat conjunctival goblet cells through ryanodine receptor type 3
    Am J Physiol Cell Physiol, 327 (3), C830-C843
    DOI 10.1152/ajpcell.00291.2024, PubMed 39099424
  8. Fineide F, Magnø M, Dahlø K, Kolko M, Heegaard S, Vehof J, Utheim TP (2024)
    Topical glaucoma medications - Possible implications on the meibomian glands
    Acta Ophthalmol, 102 (7), 735-748
    DOI 10.1111/aos.16728, PubMed 38822682
  9. Winiarczyk M, Thiede B, Utheim TP, Kaarniranta K, Winiarczyk D, Michalak K, Mackiewicz J (2024)
    Oxidative Stress, Persistent Inflammation and Blood Coagulation Alterations in Serum Proteome of Patients with Neovascular Age-Related Macular Degeneration
    Life (Basel), 14 (5)
    DOI 10.3390/life14050624, PubMed 38792644
  10. Reppe S, Gundersen S, Sandve GK, Wang Y, Andreassen OA, Medina-Gomez C, Rivadeneira F, Utheim TP, Hovig E, Gautvik KM (2024)
    Identification of Transcripts with Shared Roles in the Pathogenesis of Postmenopausal Osteoporosis and Cardiovascular Disease
    Int J Mol Sci, 25 (10)
    DOI 10.3390/ijms25105554, PubMed 38791593
  11. Hadad R, Hedengran A, Barnils A, Petrovski G, Cvenkel B, Utheim TP, Dartt DA, Heegaard S, Kolko M (2024)
    Effect of chlorhexidine, povidone-iodine and betadine antiseptic eye drops on cultured human conjunctival goblet cell survival
    Acta Ophthalmol, 102 (7), 773-778
    DOI 10.1111/aos.16684, PubMed 38553957
  12. Enayati S, Chang K, Lennikov A, Yang M, Lee C, Ashok A, Elzaridi F, Yen C, Gunes K, Xie J, Cho KS, Utheim TP, Chen DF (2024)
    Optimal transcorneal electrical stimulation parameters for preserving photoreceptors in a mouse model of retinitis pigmentosa
    Neural Regen Res, 19 (11), 2543-2552
    DOI 10.4103/1673-5374.392888, PubMed 38526290
  13. Malmin A, Thomseth VM, Førland PT, Aass HCD, Reppe S, Olsen MVT, Lindtjørn B, Chen X, Haugen IBK, Utheim TP, Forsaa VA (2024)
    Tear cytokine levels are reduced in patients treated with intravitreal injections
    Ocul Surf, 32, 222-226
    DOI 10.1016/j.jtos.2024.03.004, PubMed 38490478
  14. Galteland P, Døving M, Næss I, Sehic A, Utheim TP, Eken T, Skaga NO, Helseth E, Ramm-Pettersen J (2024)
    The association between head injury and facial fracture treatment: an observational study of hospitalized bicyclists from a level 1 trauma centre
    Acta Neurochir (Wien), 166 (1), 132
    DOI 10.1007/s00701-024-06019-9, PubMed 38472419
  15. Jensen P, Nilsen C, Gundersen M, Gundersen KG, Potvin R, Gazerani P, Chen X, Utheim TP, Utheim ØA (2024)
    A Preservative-Free Approach - Effects on Dry Eye Signs and Symptoms After Cataract Surgery
    Clin Ophthalmol, 18, 591-604
    DOI 10.2147/OPTH.S446804, PubMed 38435373
  16. Bjerager J, Magnø M, Chen X, Belmouhand M, Aass HCD, Reppe S, Heegaard S, Larsen M, Utheim TP (2024)
    Heritability of tear fluid cytokines in healthy twins
    Ocul Surf, 32, 145-153
    DOI 10.1016/j.jtos.2024.02.005, PubMed 38387783
  17. Naqvi M, Fineide F, Utheim TP, Charnock C (2024)
    Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients
    Ocul Surf, 32, 123-129
    DOI 10.1016/j.jtos.2024.02.002, PubMed 38354907
  18. van Velthoven AJH, Utheim TP, Notara M, Bremond-Gignac D, Figueiredo FC, Skottman H, Aberdam D, Daniels JT, Ferrari G, Grupcheva C, Koppen C, Parekh M, Ritter T, Romano V, Ferrari S, Cursiefen C, Lagali N, LaPointe VLS, Dickman MM (2024)
    Corrigendum to "Future directions in managing aniridia-associated keratopathy" [Surv Ophthalmol 68 (2023) 940-956]
    Surv Ophthalmol, 69 (2), 300-301
    DOI 10.1016/j.survophthal.2024.01.001, PubMed 38326136
  19. Khan AZ, Ueland HO, Bohman E, Tønseth KA, Utheim TP (2024)
    Ectropion
    Tidsskr Nor Laegeforen, 144 (1)
    DOI 10.4045/tidsskr.23.0309, PubMed 38258716
  20. Sapkota D, Wang D, Schreurs O, Vallenari EM, Pandey Dhakal S, Küntziger T, Toközlü BS, Utheim TP, Chaudhry FA (2024)
    Investigation of Roles of SLC38A1 in Proliferation and Differentiation of Mouse Tongue Epithelium and Expression in Human Oral Tongue Squamous Cell Carcinoma
    Cancers (Basel), 16 (2)
    DOI 10.3390/cancers16020405, PubMed 38254895
  21. Nøland ST, Magnø MS, Utheim TP, Chen X (2024)
    Sex Differences in the Prevalence of Meibomian Gland Dysfunction: A Mini Review
    Curr Eye Res, 49 (5), 447-457
    DOI 10.1080/02713683.2023.2301325, PubMed 38196124
  22. Storås AM, Fineide F, Magnø M, Thiede B, Chen X, Strümke I, Halvorsen P, Galtung H, Jensen JL, Utheim TP, Riegler MA (2023)
    Using machine learning model explanations to identify proteins related to severity of meibomian gland dysfunction
    Sci Rep, 13 (1), 22946
    DOI 10.1038/s41598-023-50342-7, PubMed 38135766
  23. Møller-Hansen M, Larsen AC, Wiencke AK, Terslev L, Siersma V, Andersen TT, Hansen AE, Bruunsgaard H, Haack-Sørensen M, Ekblond A, Kastrup J, Utheim TP, Heegaard S (2023)
    Allogeneic mesenchymal stem cell therapy for dry eye disease in patients with Sjögren's syndrome: A randomized clinical trial
    Ocul Surf, 31, 1-8
    DOI 10.1016/j.jtos.2023.11.007, PubMed 38049032
  24. Fineide FA, Tashbayev B, Elgstøen KBP, Sandås EM, Rootwelt H, Hynne H, Chen X, Ræder S, Vehof J, Dartt D, Jensen JL, Utheim TP (2023)
    Tear and Saliva Metabolomics in Evaporative Dry Eye Disease in Females
    Metabolites, 13 (11)
    DOI 10.3390/metabo13111125, PubMed 37999221
  25. Tashbayev B, Chen X, Utheim TP (2024)
    Chalazion Treatment: A Concise Review of Clinical Trials
    Curr Eye Res, 49 (2), 109-118
    DOI 10.1080/02713683.2023.2279014, PubMed 37937798
  26. Cross T, Øvstebø R, Brusletto BS, Trøseid AS, Olstad OK, Aspelin T, Jackson CJ, Chen X, Utheim TP, Haug KBF (2023)
    RNA Profiles of Tear Fluid Extracellular Vesicles in Patients with Dry Eye-Related Symptoms
    Int J Mol Sci, 24 (20)
    DOI 10.3390/ijms242015390, PubMed 37895069
  27. Muttuvelu DV, Cehofski LJ, Holtz J, Utheim TP, Chen X, Vorum H, Heegaard S, Rasmussen MLR, Khan AM, Abduljabar AB, Honoré B (2023)
    Meibomian Gland Dysfunction Is Associated with Low Levels of Immunoglobulin Chains and Cystatin-SN
    Int J Mol Sci, 24 (20)
    DOI 10.3390/ijms242015115, PubMed 37894795
  28. Muttuvelu DV, Cehofski LJ, Utheim TP, Chen X, Vorum H, Rasmussen MLR, Heegaard S, Khan AM, Abduljabar AB, Honoré B (2023)
    Tear film proteome changes following Tobradex® therapy in anterior blepharitis
    Acta Ophthalmol, 102 (4), e565-e576
    DOI 10.1111/aos.15792, PubMed 37837306
  29. Hedengran A, Freiberg J, May Hansen P, Boix-Lemonche G, Utheim TP, Dartt DA, Petrovski G, Heegaard S, Kolko M (2023)
    Comparing the effect of benzalkonium chloride-preserved, polyquad-preserved, and preservative-free prostaglandin analogue eye drops on cultured human conjunctival goblet cells
    J Optom, 17 (1), 100481
    DOI 10.1016/j.optom.2023.100481, PubMed 37788596
  30. Magno MS, Moschowits E, Morthen MK, Beining MW, Jansonius NM, Hammond CJ, Utheim TP, Vehof J (2023)
    Greater adherence to a mediterranean diet is associated with lower C-reactive protein (CRP) levels, but not to lower odds of having dry eye disease
    Ocul Surf, 30, 196-203
    DOI 10.1016/j.jtos.2023.09.013, PubMed 37783428
  31. Erøy ÅA, Utheim TP, Sundling V (2023)
    Cross-sectional Study Exploring Vision-related Quality of Life in Dry Eye Disease in a Norwegian Optometric Practice
    Optom Vis Sci, 100 (10), 679-687
    DOI 10.1097/OPX.0000000000002058, PubMed 37751404
  32. Fineide F, Magnø MS, Khan AZ, Chen X, Vehof J, Utheim TP (2023)
    Intense pulsed light treatment in meibomian gland dysfunction: Past, present, and future
    Acta Ophthalmol, 102 (4), e414-e442
    DOI 10.1111/aos.15759, PubMed 37702308
  33. Cross T, Haug KBF, Brusletto BS, Ommundsen SK, Trøseid AS, Aspelin T, Olstad OK, Aass HCD, Galtung HK, Utheim TP, Jensen JL, Øvstebø R (2023)
    Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics?
    Int J Mol Sci, 24 (17)
    DOI 10.3390/ijms241713409, PubMed 37686214
  34. Ballet B, Behaegel J, Reppe S, Consejo A, Aass HC, Utheim TP, Koppen C, Ní Dhubhghaill S (2023)
    Ocular Surface Homeostasis After Scleral Lens Usage
    Eye Contact Lens, 49 (11), 459-463
    DOI 10.1097/ICL.0000000000001027, PubMed 37651199
  35. Ashok A, Tai WL, Lennikov A, Chang K, Chen J, Li B, Cho KS, Utheim TP, Chen DF (2023)
    Electrical stimulation alters DNA methylation and promotes neurite outgrowth
    J Cell Biochem, 124 (10), 1530-1545
    DOI 10.1002/jcb.30462, PubMed 37642194
  36. Fjærvoll HK, Fjærvoll KA, Yang M, Bair J, Utheim TP, Dartt DA (2023)
    Purinergic 2X 4 (P2X4), but not P2X7, receptors increase cytosolic [Ca2+] and stimulate mucin secretion in rat conjunctival goblet cells to maintain ocular surface health
    Exp Eye Res, 235, 109614
    DOI 10.1016/j.exer.2023.109614, PubMed 37580003
  37. Møller-Hansen M, Utheim TP, Heegaard S (2023)
    Surgical Procedures in the Treatment of Dry Eye Disease
    J Ocul Pharmacol Ther, 39 (10), 692-698
    DOI 10.1089/jop.2023.0063, PubMed 37566528
  38. Lyngstadaas AV, Olsen MV, Bair J, Yang M, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2023)
    Anti-Inflammatory and Pro-Resolving Actions of the N-Terminal Peptides Ac2-26, Ac2-12, and Ac9-25 of Annexin A1 on Conjunctival Goblet Cell Function
    Am J Pathol, 193 (11), 1817-1832
    DOI 10.1016/j.ajpath.2023.05.020, PubMed 37423551
  39. Khan AZ, Tønseth KA, Koidl A, Utheim TP (2023)
    [Not Available]
    Tidsskr Nor Laegeforen, 143
    DOI 10.4045/tidsskr.23.0446, PubMed 37376981
  40. Khan AZ, Tønseth KA, Koidl A, Utheim TP (2023)
    Suture materials
    Tidsskr Nor Laegeforen, 143 (10)
    DOI 10.4045/tidsskr.22.0708, PubMed 37376937
  41. Muttuvelu DV, Cehofski LJ, Muhammad MGF, Chen X, Utheim TP, Khan AM, Abduljabar AB, Kristensen K, Rasmussen MLR, Vorum H, Heegaard S, Honoré B (2023)
    Anterior blepharitis is associated with elevated plectin levels consistent with a pronounced intracellular response
    Ocul Surf, 29, 444-455
    DOI 10.1016/j.jtos.2023.06.010, PubMed 37348651
  42. Kolko M, Gazzard G, Baudouin C, Beier S, Brignole-Baudouin F, Cvenkel B, Fineide F, Hedengran A, Hommer A, Jespersen E, Messmer EM, Murthy R, Sullivan AG, Tatham AJ, Utheim TP, Vittrup M, Sullivan DA (2023)
    Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment
    Ocul Surf, 29, 456-468
    DOI 10.1016/j.jtos.2023.05.012, PubMed 37302545
  43. Hiller JK, Sandås EM, Rootwelt H, Østeby Vassli A, Utheim TP, Moe MC, Elgstøen KBP, Petrovski G (2023)
    Ex Vivo Pig Eye Model for Studying Diffusion of Acylcarnitines with Different Physicochemical Properties
    J Ocul Pharmacol Ther, 39 (5), 324-331
    DOI 10.1089/jop.2022.0159, PubMed 37219540
  44. van Velthoven AJH, Utheim TP, Notara M, Bremond-Gignac D, Figueiredo FC, Skottman H, Aberdam D, Daniels JT, Ferrari G, Grupcheva C, Koppen C, Parekh M, Ritter T, Romano V, Ferrari S, Cursiefen C, Lagali N, LaPointe VLS, Dickman MM (2023)
    Future directions in managing aniridia-associated keratopathy
    Surv Ophthalmol, 68 (5), 940-956
    DOI 10.1016/j.survophthal.2023.04.003, PubMed 37146692
  45. Graae Jensen P, Gundersen M, Nilsen C, Gundersen KG, Potvin R, Gazerani P, Chen X, Utheim TP, Utheim ØA (2023)
    Prevalence of Dry Eye Disease Among Individuals Scheduled for Cataract Surgery in a Norwegian Cataract Clinic
    Clin Ophthalmol, 17, 1233-1243
    DOI 10.2147/OPTH.S407805, PubMed 37138823
  46. Pedersen HR, Gilson SJ, Landsend ECS, Utheim ØA, Utheim TP, Baraas RC (2023)
    Rod and Cone Dark Adaptation in Congenital Aniridia and Its Association With Retinal Structure
    Invest Ophthalmol Vis Sci, 64 (4), 18
    DOI 10.1167/iovs.64.4.18, PubMed 37067366
  47. Wolffsohn JS, Lingham G, Downie LE, Huntjens B, Inomata T, Jivraj S, Kobia-Acquah E, Muntz A, Mohamed-Noriega K, Plainis S, Read M, Sayegh RR, Singh S, Utheim TP, Craig JP (2023)
    TFOS Lifestyle: Impact of the digital environment on the ocular surface
    Ocul Surf, 28, 213-252
    DOI 10.1016/j.jtos.2023.04.004, PubMed 37062428
  48. Badian RA, Ekman L, Pripp AH, Utheim TP, Englund E, Dahlin LB, Rolandsson O, Lagali N (2023)
    Comparison of Novel Wide-Field In Vivo Corneal Confocal Microscopy With Skin Biopsy for Assessing Peripheral Neuropathy in Type 2 Diabetes
    Diabetes, 72 (7), 908-917
    DOI 10.2337/db22-0863, PubMed 37058418
  49. Hynnekleiv L, Magno M, Moschowits E, Tønseth KA, Vehof J, Utheim TP (2023)
    A comparison between hyaluronic acid and other single ingredient eye drops for dry eye, a review
    Acta Ophthalmol, 102 (1), 25-37
    DOI 10.1111/aos.15675, PubMed 37042308
  50. Magno MS, Olafsson J, Beining M, Moschowits E, Lagali N, Wolffsohn JS, Craig JP, Vehof J, Dartt DA, Utheim TP (2023)
    Risk associated with treatments for meibomian gland dysfunction
    Cont Lens Anterior Eye, 46 (2), 101818
    DOI 10.1016/j.clae.2023.101818, PubMed 36754735
  51. Schjerven Magno M, Olafsson J, Beining M, Moschowits E, Lagali N, Wolffsohn JS, Craig JP, Vehof J, Dartt DA, Utheim TP (2022)
    Hot towels: The bedrock of Meibomian gland dysfunction treatment - A review
    Cont Lens Anterior Eye, 46 (2), 101775
    DOI 10.1016/j.clae.2022.101775, PubMed 36715292
  52. Malmin A, Thomseth VM, Førland PT, Khan AZ, Hetland HB, Chen X, Haugen IK, Utheim TP, Forsaa VA (2023)
    Associations between Serial Intravitreal Injections and Dry Eye
    Ophthalmology, 130 (5), 509-515
    DOI 10.1016/j.ophtha.2023.01.009, PubMed 36693594
  53. Morthen MK, Magno MS, Utheim TP, Hammond CJ, Vehof J (2023)
    The work-related burden of dry eye
    Ocul Surf, 28, 30-36
    DOI 10.1016/j.jtos.2023.01.006, PubMed 36690155
  54. Nguyen L, Magno MS, Utheim TP, Hammond CJ, Vehof J (2023)
    The relationship between sedentary behavior and dry eye disease
    Ocul Surf, 28, 11-17
    DOI 10.1016/j.jtos.2023.01.002, PubMed 36621639
  55. Zartasht Khan A, Utheim TP, Eidet JR (2022)
    Retinal Pigment Epithelium Transplantation: Past, Present, and Future
    J Ophthalmic Vis Res, 17 (4), 574-580
    DOI 10.18502/jovr.v17i4.12325, PubMed 36620704
  56. Galteland P, Næss I, Døving M, Sehic A, Utheim TP, Skaga NO, Eken T, Helseth E, Ramm-Pettersen J (2022)
    Facial Fractures and Their Relation to Head and Cervical Spine Injuries in Hospitalized Bicyclists
    J Craniofac Surg, 34 (1), 34-39
    DOI 10.1097/SCS.0000000000009032, PubMed 36608095
  57. Jackson CJ, Naqvi M, Gundersen KG, Utheim TP (2022)
    Role of stem cells in regenerative treatment of dry eye disease caused by lacrimal gland dysfunction
    Acta Ophthalmol, 101 (4), 360-375
    DOI 10.1111/aos.15629, PubMed 36564971
  58. Yang M, Lennikov A, Chang K, Ashok A, Lee C, Cho KS, Utheim TP, Dartt DA, Chen DF (2022)
    Transcorneal but not transpalpebral electrical stimulation disrupts mucin homeostasis of the ocular surface
    BMC Ophthalmol, 22 (1), 490
    DOI 10.1186/s12886-022-02717-z, PubMed 36522696
  59. Fries FN, Moslemani K, Utheim TP, Seitz B, Käsmann-Kellner B, Lagali NS (2023)
    Early ocular surface and tear film status in congenital aniridia indicates a supportive treatment window
    Br J Ophthalmol, 108 (1), 30-36
    DOI 10.1136/bjo-2021-320774, PubMed 36517210
  60. Fineide F, Storås AM, Chen X, Magnø MS, Yazidi A, Riegler MA, Utheim TP (2022)
    Predicting an unstable tear film through artificial intelligence
    Sci Rep, 12 (1), 21416
    DOI 10.1038/s41598-022-25821-y, PubMed 36496510
  61. Eidet JR, Chen X, Ræder S, Badian RA, Utheim TP (2022)
    Seasonal variations in presenting symptoms and signs of dry eye disease in Norway
    Sci Rep, 12 (1), 21046
    DOI 10.1038/s41598-022-25557-9, PubMed 36473933
  62. Jirsova K, Levova K, Kalousova M, Fales I, Frankova V, Vesela V, Zima T, Utheim TP, Bednar J (2022)
    Time and Temperature Stability of TGF-β1, EGF and IGF-1 in 20% and 100% Human Serum
    Folia Biol (Praha), 68 (2), 45-49
    PubMed 36384261
  63. Vernhardsdottir RR, Magno MS, Hynnekleiv L, Lagali N, Dartt DA, Vehof J, Jackson CJ, Utheim TP (2022)
    Antibiotic treatment for dry eye disease related to meibomian gland dysfunction and blepharitis - A review
    Ocul Surf, 26, 211-221
    DOI 10.1016/j.jtos.2022.08.010, PubMed 36210626
  64. Gautvik KM, Olstad OK, Raue U, Gautvik VT, Kvernevik KJ, Utheim TP, Ravnum S, Kirkegaard C, Wiig H, Jones G, Pilling LC, Trappe S, Raastad T, Reppe S (2022)
    Heavy-load exercise in older adults activates vasculogenesis and has a stronger impact on muscle gene expression than in young adults
    Eur Rev Aging Phys Act, 19 (1), 23
    DOI 10.1186/s11556-022-00304-1, PubMed 36182918
  65. Yang M, Fjærvoll HK, Fjærvoll KA, Wang NH, Utheim TP, Serhan CN, Dartt DA (2022)
    Sex-based differences in conjunctival goblet cell responses to pro-inflammatory and pro-resolving mediators
    Sci Rep, 12 (1), 16305
    DOI 10.1038/s41598-022-20177-9, PubMed 36175572
  66. Lennikov A, Yang M, Chang K, Pan L, Saddala MS, Lee C, Ashok A, Cho KS, Utheim TP, Chen DF (2022)
    Direct modulation of microglial function by electrical field
    Front Cell Dev Biol, 10, 980775
    DOI 10.3389/fcell.2022.980775, PubMed 36158207
  67. Botten N, Hodges RR, Bair J, Utheim TP, Serhan CN, Yang M, Dartt DA (2022)
    Resolvin D2 uses multiple Ca2+ -dependent signaling pathways to stimulate mucin secretion in rat and human conjunctival goblet cells
    J Cell Physiol, 237 (10), 3816-3833
    DOI 10.1002/jcp.30854, PubMed 36066128
  68. Ashok A, Pooranawattanakul S, Tai WL, Cho KS, Utheim TP, Cestari DM, Chen DF (2022)
    Epigenetic Regulation of Optic Nerve Development, Protection, and Repair
    Int J Mol Sci, 23 (16)
    DOI 10.3390/ijms23168927, PubMed 36012190
  69. Landsend ECS, Olafsson J, Lai X, Aass HCD, Utheim TP (2022)
    Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels
    J Ophthalmol, 2022, 5103231
    DOI 10.1155/2022/5103231, PubMed 35967518
  70. Nguyen L, Magno MS, Utheim TP, Jansonius NM, Hammond CJ, Vehof J (2022)
    The relationship between habitual water intake and dry eye disease
    Acta Ophthalmol, 101 (1), 65-73
    DOI 10.1111/aos.15227, PubMed 35941821
  71. Fineide F, Lagali N, Adil MY, Arita R, Kolko M, Vehof J, Utheim TP (2022)
    Topical glaucoma medications - Clinical implications for the ocular surface
    Ocul Surf, 26, 19-49
    DOI 10.1016/j.jtos.2022.07.007, PubMed 35921942
  72. Gautvik KM, Sachse D, Hinton AC, Olstad OK, Kiel DP, Hsu YH, Utheim TP, Lary CW, Reppe S (2022)
    In silico discovery of blood cell macromolecular associations
    BMC Genom Data, 23 (1), 57
    DOI 10.1186/s12863-022-01077-3, PubMed 35879676
  73. Liu P, Lin X, Chen X, Utheim TP, Gao W, Yan Y, Wu S (2022)
    Neuronal Intranuclear Inclusion Disease-Related Neurotrophic Keratitis: A Case Report
    Brain Sci, 12 (6)
    DOI 10.3390/brainsci12060782, PubMed 35741666
  74. Hynne H, Tashbayev B, Diep MT, Sødal ATT, Badian RA, Chen X, Lai X, Utheim TP, Hove LH, Jensen JL (2022)
    The relationship between ocular and oral dryness in a cohort from the 65-year-old population in Norway
    Sci Rep, 12 (1), 9805
    DOI 10.1038/s41598-022-13985-6, PubMed 35697848
  75. Feng Y, Reinstein DZ, Nitter T, Archer TJ, McAlinden C, Chen X, Bertelsen G, Utheim TP, Stojanovic A (2022)
    Heidelberg Anterion Swept-Source OCT Corneal Epithelial Thickness Mapping: Repeatability and Agreement With Optovue Avanti
    J Refract Surg, 38 (6), 356-363
    DOI 10.3928/1081597X-20220414-01, PubMed 35686707
  76. Olsen MV, Lyngstadaas AV, Bair JA, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2022)
    Signaling Pathways Used by the Specialized Pro-Resolving Mediator Maresin 2 Regulate Goblet Cell Function: Comparison with Maresin 1
    Int J Mol Sci, 23 (11)
    DOI 10.3390/ijms23116233, PubMed 35682912
  77. Bhandari M, Nguyen S, Yazdani M, Utheim TP, Hagesaether E (2022)
    The Therapeutic Benefits of Nanoencapsulation in Drug Delivery to the Anterior Segment of the Eye: A Systematic Review
    Front Pharmacol, 13, 903519
    DOI 10.3389/fphar.2022.903519, PubMed 35645827
  78. Khan AZ, Utheim TP, Byholt M, Fiabema T, Sylvester-Jensen HC, Tønseth KA (2022)
    Skin grafting
    Tidsskr Nor Laegeforen, 142 (8)
    DOI 10.4045/tidsskr.21.0671, PubMed 35635412
  79. Thein AS, Hedengran A, Azuara-Blanco A, Arita R, Cvenkel B, Gazzard G, Heegaard S, de Paiva CS, Petrovski G, Prokosch-Willing V, Utheim TP, Virgili G, Kolko M (2022)
    Adverse Effects and Safety in Glaucoma Patients: Agreement on Clinical Trial Outcomes for Reports on Eye Drops (ASGARD)-A Delphi Consensus Statement
    Am J Ophthalmol, 241, 190-197
    DOI 10.1016/j.ajo.2022.05.007, PubMed 35594917
  80. Enayati S, Zhou W, Stojanovic A, Utheim TP, Bian Z, Feng Y, Chen X (2022)
    Effect of femtosecond laser cutting parameters on the results of small-incision lenticule extraction
    J Cataract Refract Surg, 48 (11), 1253-1259
    DOI 10.1097/j.jcrs.0000000000000965, PubMed 35537865
  81. Hynnekleiv L, Magno M, Vernhardsdottir RR, Moschowits E, Tønseth KA, Dartt DA, Vehof J, Utheim TP (2022)
    Hyaluronic acid in the treatment of dry eye disease
    Acta Ophthalmol, 100 (8), 844-860
    DOI 10.1111/aos.15159, PubMed 35514082
  82. Døving M, Naess I, Galteland P, Ramm-Pettersen J, Dalby M, Utheim TP, Skaga NO, Helseth E, Sehic A (2022)
    Anatomical distribution of mandibular fractures from severe bicycling accidents: A 12-year experience from a Norwegian level 1 trauma center
    Dent Traumatol, 38 (5), 424-430
    DOI 10.1111/edt.12756, PubMed 35481880
  83. Fjaervoll K, Fjaervoll H, Magno M, Nøland ST, Dartt DA, Vehof J, Utheim TP (2022)
    Review on the possible pathophysiological mechanisms underlying visual display terminal-associated dry eye disease
    Acta Ophthalmol, 100 (8), 861-877
    DOI 10.1111/aos.15150, PubMed 35441459
  84. Hynne H, Aqrawi LA, Jensen JL, Thiede B, Palm Ø, Amdal CD, Westgaard KL, Herlofson BB, Utheim TP, Galtung HK (2022)
    Proteomic Profiling of Saliva and Tears in Radiated Head and Neck Cancer Patients as Compared to Primary Sjögren's Syndrome Patients
    Int J Mol Sci, 23 (7)
    DOI 10.3390/ijms23073714, PubMed 35409074
  85. Bakken IM, Jackson CJ, Utheim TP, Villani E, Hamrah P, Kheirkhah A, Nielsen E, Hau S, Lagali NS (2022)
    The use of in vivo confocal microscopy in fungal keratitis - Progress and challenges
    Ocul Surf, 24, 103-118
    DOI 10.1016/j.jtos.2022.03.002, PubMed 35278721
  86. Jackson CJ, Gundersen KG, Tong L, Utheim TP (2022)
    Dry eye disease and proteomics
    Ocul Surf, 24, 119-128
    DOI 10.1016/j.jtos.2022.03.001, PubMed 35278720
  87. Salvanos P, Björnsson HD, Vitelli V, Bragadόttir R, Moe MC, Utheim TP (2022)
    Autofluorescence Imaging in the Long-Term Follow-Up of Scleral Buckling Surgery for Retinal Detachment
    J Ophthalmol, 2022, 2119439
    DOI 10.1155/2022/2119439, PubMed 35265365
  88. Achour H, Thomseth VM, Kvaløy JT, Krohn J, Utheim TP, Forsaa VA (2022)
    Substantial increase in the incidence of rhegmatogenous retinal detachment in Western Norway over 20 years
    Acta Ophthalmol, 100 (7), 763-768
    DOI 10.1111/aos.15119, PubMed 35261167
  89. Beining MW, Magnø MS, Moschowits E, Olafsson J, Vehof J, Dartt DA, Utheim TP (2022)
    In-office thermal systems for the treatment of dry eye disease
    Surv Ophthalmol, 67 (5), 1405-1418
    DOI 10.1016/j.survophthal.2022.02.007, PubMed 35192836
  90. Haugen ØP, Khuu C, Weidemann HM, Utheim TP, Bergersen LH (2022)
    Transcriptomic and functional studies reveal miR-431-5p as a tumour suppressor in pancreatic ductal adenocarcinoma cells
    Gene, 822, 146346
    DOI 10.1016/j.gene.2022.146346, PubMed 35182679
  91. Chen X, Badian RA, Hynne H, Tashbayev B, Hove LH, Jensen JL, Utheim TP (2022)
    Morphology of Meibomian Glands in a 65-Year-Old Norwegian Population without Dry Eye Disease
    J Clin Med, 11 (3)
    DOI 10.3390/jcm11030527, PubMed 35159978
  92. Hynne H, Sandås EM, Elgstøen KBP, Rootwelt H, Utheim TP, Galtung HK, Jensen JL (2022)
    Saliva Metabolomics in Dry Mouth Patients with Head and Neck Cancer or Sjögren's Syndrome
    Cells, 11 (3)
    DOI 10.3390/cells11030323, PubMed 35159133
  93. Kamøy B, Magno M, Nøland ST, Moe MC, Petrovski G, Vehof J, Utheim TP (2022)
    Video display terminal use and dry eye: preventive measures and future perspectives
    Acta Ophthalmol, 100 (7), 723-739
    DOI 10.1111/aos.15105, PubMed 35122403
  94. Magno MS, Utheim TP, Morthen MK, Snieder H, Jansonius NM, Hammond CJ, Vehof J (2022)
    The Relationship Between Caffeine Intake and Dry Eye Disease
    Cornea, 42 (2), 186-193
    DOI 10.1097/ICO.0000000000002979, PubMed 35081066
  95. Yang M, Botten N, Hodges R, Bair J, Utheim TP, Serhan CN, Dartt DA (2021)
    Resolvin D2 and Resolvin D1 Differentially Activate Protein Kinases to Counter-Regulate Histamine-Induced [Ca2+]i Increase and Mucin Secretion in Conjunctival Goblet Cells
    Int J Mol Sci, 23 (1)
    DOI 10.3390/ijms23010141, PubMed 35008563
  96. Müllertz O, Hedengran A, Mouhammad ZA, Freiberg J, Nagymihály R, Jacobsen J, Larsen SW, Bair J, Utheim TP, Dartt DA, Heegaard S, Petrovski G, Kolko M (2021)
    Impact of benzalkonium chloride-preserved and preservative-free latanoprost eye drops on cultured human conjunctival goblet cells upon acute exposure and differences in physicochemical properties of the eye drops
    BMJ Open Ophthalmol, 6 (1), e000892
    DOI 10.1136/bmjophth-2021-000892, PubMed 34993350
  97. Badian RA, Utheim TP, Chen X, Utheim ØA, Ræder S, Ystenæs AE, Aakre BM, Sundling V (2021)
    Meibomian gland dysfunction is highly prevalent among first-time visitors at a Norwegian dry eye specialist clinic
    Sci Rep, 11 (1), 23412
    DOI 10.1038/s41598-021-02738-6, PubMed 34862425
  98. Storås AM, Strümke I, Riegler MA, Grauslund J, Hammer HL, Yazidi A, Halvorsen P, Gundersen KG, Utheim TP, Jackson CJ (2021)
    Artificial intelligence in dry eye disease
    Ocul Surf, 23, 74-86
    DOI 10.1016/j.jtos.2021.11.004, PubMed 34843999
  99. Badian RA, Allgeier S, Scarpa F, Andréasson M, Bartschat A, Mikut R, Colonna A, Bellisario M, Utheim TP, Köhler B, Svenningsson P, Lagali N (2021)
    Wide-field mosaics of the corneal subbasal nerve plexus in Parkinson's disease using in vivo confocal microscopy
    Sci Data, 8 (1), 306
    DOI 10.1038/s41597-021-01087-3, PubMed 34836991
  100. Chen X, Badian RA, Hynne H, Amdal CD, Herlofson BB, Utheim ØA, Westgaard KL, Fineide F, Jensen JL, Utheim TP (2021)
    Alterations in meibomian glands in patients treated with intensity-modulated radiotherapy for head and neck cancer
    Sci Rep, 11 (1), 22419
    DOI 10.1038/s41598-021-01844-9, PubMed 34789830
  101. Olafsson J, Lai X, Landsend ECS, Olafsson S, Parissi E, Utheim ØA, Raeder S, Badian RA, Lagali N, Dartt DA, Utheim TP (2021)
    TheraPearl Eye Mask and Blephasteam for the treatment of meibomian gland dysfunction: a randomized, comparative clinical trial
    Sci Rep, 11 (1), 22386
    DOI 10.1038/s41598-021-01899-8, PubMed 34789807
  102. Magno MS, Olafsson J, Beining M, Moschowits E, Lagali N, Wolffsohn JS, Craig JP, Dartt DA, Vehof J, Utheim TP (2021)
    Chambered warm moist air eyelid warming devices - a review
    Acta Ophthalmol, 100 (5), 499-510
    DOI 10.1111/aos.15052, PubMed 34750979
  103. Landsend ECS, Lagali N, Utheim TP (2021)
    Authors' response to letter to the editor: Congenital aniridia - a comprehensive review of clinical features and therapeutic approach
    Surv Ophthalmol, 67 (2), 629-630
    DOI 10.1016/j.survophthal.2021.11.001, PubMed 34748793
  104. Morthen MK, Magno MS, Utheim TP, Snieder H, Jansonius N, Hammond CJ, Vehof J (2021)
    The vision-related burden of dry eye
    Ocul Surf, 23, 207-215
    DOI 10.1016/j.jtos.2021.10.007, PubMed 34743866
  105. Smeringaiova I, Utheim TP, Jirsova K (2021)
    Ex vivo expansion and characterization of human corneal endothelium for transplantation: a review
    Stem Cell Res Ther, 12 (1), 554
    DOI 10.1186/s13287-021-02611-3, PubMed 34717745
  106. Fjaervoll H, Fjaervoll K, Magno M, Moschowits E, Vehof J, Dartt DA, Utheim TP (2021)
    The association between visual display terminal use and dry eye: a review
    Acta Ophthalmol, 100 (4), 357-375
    DOI 10.1111/aos.15049, PubMed 34697901
  107. Tulek A, Mulic A, Hogset M, Utheim TP, Sehic A (2021)
    Therapeutic Strategies for Dry Mouth Management with Emphasis on Electrostimulation as a Treatment Option
    Int J Dent, 2021, 6043488
    DOI 10.1155/2021/6043488, PubMed 34691182
  108. Khan AZ, Utheim TP, Jackson CJ, Tønseth KA, Eidet JR (2021)
    Corrigendum: Concise Review: Considering Optimal Temperature for Short-Term Storage of Epithelial Cells
    Front Med (Lausanne), 8, 775351
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  109. Khan AZ, Utheim TP, Jackson CJ, Tønseth KA, Eidet JR (2021)
    Concise Review: Considering Optimal Temperature for Short-Term Storage of Epithelial Cells
    Front Med (Lausanne), 8, 686774
    DOI 10.3389/fmed.2021.686774, PubMed 34485330
  110. Badian RA, Andréasson M, Svenningsson P, Utheim TP, Lagali N (2021)
    The pattern of the inferocentral whorl region of the corneal subbasal nerve plexus is altered with age
    Ocul Surf, 22, 204-212
    DOI 10.1016/j.jtos.2021.08.015, PubMed 34450219
  111. Fineide F, Chen X, Bjellaas T, Vitelli V, Utheim TP, Jensen JL, Galtung HK (2021)
    Characterization of Lipids in Saliva, Tears and Minor Salivary Glands of Sjögren's Syndrome Patients Using an HPLC/MS-Based Approach
    Int J Mol Sci, 22 (16)
    DOI 10.3390/ijms22168997, PubMed 34445702
  112. Yazdani M, Elgstøen KBP, Utheim TP (2021)
    Eye Make-up Products and Dry Eye Disease: A Mini Review
    Curr Eye Res, 47 (1), 1-11
    DOI 10.1080/02713683.2021.1966476, PubMed 34365876
  113. Tulek A, Mulic A, Runningen M, Lillemo J, Utheim TP, Khan Q, Sehic A (2021)
    Genetic Aspects of Dental Erosive Wear and Dental Caries
    Int J Dent, 2021, 5566733
    DOI 10.1155/2021/5566733, PubMed 34335772
  114. Zhou W, Reinstein DZ, Archer TJ, Chen X, Utheim TP, Feng Y, Stojanovic A (2021)
    Intraoperative Swept-Source OCT-Based Corneal Topography for Measurement and Analysis of Stromal Surface After Epithelial Removal
    J Refract Surg, 37 (7), 484-492
    DOI 10.3928/1081597X-20210405-01, PubMed 34236903
  115. Wolpert LE, Snieder H, Jansonius NM, Utheim TP, Hammond CJ, Vehof J (2021)
    Medication use and dry eye symptoms: A large, hypothesis-free, population-based study in the Netherlands
    Ocul Surf, 22, 1-12
    DOI 10.1016/j.jtos.2021.06.009, PubMed 34171471
  116. Hamdani EH, Popek M, Frontczak-Baniewicz M, Utheim TP, Albrecht J, Zielińska M, Chaudhry FA (2021)
    Perturbation of astroglial Slc38 glutamine transporters by NH4+ contributes to neurophysiologic manifestations in acute liver failure
    FASEB J, 35 (7), e21588
    DOI 10.1096/fj.202001712RR, PubMed 34169573
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    The physical and mental burden of dry eye disease: A large population-based study investigating the relationship with health-related quality of life and its determinants
    Ocul Surf, 21, 107-117
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  118. Magno MS, Daniel T, Morthen MK, Snieder H, Jansonius N, Utheim TP, Hammond CJ, Vehof J (2021)
    The relationship between alcohol consumption and dry eye
    Ocul Surf, 21, 87-95
    DOI 10.1016/j.jtos.2021.05.005, PubMed 34029755
  119. Døving M, Anandan S, Rogne KG, Utheim TP, Brunborg C, Galteland P, Sunde K (2021)
    Cost Analysis of Open Surgical Bedside Tracheostomy in Intensive Care Unit Patients
    Ear Nose Throat J, 102 (8), 516-521
    DOI 10.1177/01455613211018578, PubMed 34006128
  120. Lyngstadaas AV, Olsen MV, Bair JA, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2021)
    Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca2+ and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases
    Front Immunol, 12, 618653
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  121. Hikage F, Lennikov A, Mukwaya A, Lachota M, Ida Y, Utheim TP, Chen DF, Huang H, Ohguro H (2021)
    NF-κB activation in retinal microglia is involved in the inflammatory and neovascularization signaling in laser-induced choroidal neovascularization in mice
    Exp Cell Res, 403 (1), 112581
    DOI 10.1016/j.yexcr.2021.112581, PubMed 33811906
  122. Landsend ECS, Lagali N, Utheim TP (2021)
    Congenital aniridia - A comprehensive review of clinical features and therapeutic approaches
    Surv Ophthalmol, 66 (6), 1031-1050
    DOI 10.1016/j.survophthal.2021.02.011, PubMed 33675823
  123. Yazdani M, Fiskådal J, Chen X, Utheim ØA, Ræder S, Vitelli V, Utheim TP (2021)
    Tear Film Break-Up Time and Dry Eye Disease Severity in a Large Norwegian Cohort
    J Clin Med, 10 (4)
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  124. Westgaard KL, Hynne H, Amdal CD, Young A, Singh PB, Chen X, Rykke M, Hove LH, Aqrawi LA, Utheim TP, Herlofson BB, Jensen JL (2021)
    Oral and ocular late effects in head and neck cancer patients treated with radiotherapy
    Sci Rep, 11 (1), 4026
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  125. Thomseth VM, Ushakova A, Krohn J, Utheim TP, Austeng D, Fossen K, Varhaug P, Malmin A, Skeiseid L, Tharaldsen A, Lindtjørn B, Johannesen H, Juul J, Forsaa VA (2021)
    STRUCTURAL PATHOLOGY AFTER RETINAL DETACHMENT: Multicolor Confocal Scanning Laser Ophthalmoscopy Versus Color Fundus Photography
    Retina, 41 (9), 1958-1965
    DOI 10.1097/IAE.0000000000003113, PubMed 33464027
  126. Chang K, Enayati S, Cho KS, Utheim TP, Chen DF (2021)
    Non-invasive electrical stimulation as a potential treatment for retinal degenerative diseases
    Neural Regen Res, 16 (8), 1558-1559
    DOI 10.4103/1673-5374.303015, PubMed 33433481
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    The relationship between dry eye and sleep quality
    Ocul Surf, 20, 13-19
    DOI 10.1016/j.jtos.2020.12.009, PubMed 33421635
  128. Andréasson M, Lagali N, Badian RA, Utheim TP, Scarpa F, Colonna A, Allgeier S, Bartschat A, Köhler B, Mikut R, Reichert KM, Solders G, Samuelsson K, Zetterberg H, Blennow K, Svenningsson P (2021)
    Parkinson's disease with restless legs syndrome-an in vivo corneal confocal microscopy study
    NPJ Parkinsons Dis, 7 (1), 4
    DOI 10.1038/s41531-020-00148-5, PubMed 33402694
  129. Magno M, Moschowits E, Arita R, Vehof J, Utheim TP (2021)
    Intraductal meibomian gland probing and its efficacy in the treatment of meibomian gland dysfunction
    Surv Ophthalmol, 66 (4), 612-622
    DOI 10.1016/j.survophthal.2020.11.005, PubMed 33352147
  130. Yazdani M, Shahdadfar A, Reppe S, Sapkota D, Vallenari EM, Lako M, Connon CJ, Figueiredo FC, Utheim TP (2020)
    Response of human oral mucosal epithelial cells to different storage temperatures: A structural and transcriptional study
    PLoS One, 15 (12), e0243914
    DOI 10.1371/journal.pone.0243914, PubMed 33326470
  131. Islam R, Corraya RM, Pasovic L, Khan AZ, Aass HCD, Eidet JR, Utheim TP (2020)
    The Effects of Prolonged Storage on ARPE-19 Cells Stored at Three Different Storage Temperatures
    Molecules, 25 (24)
    DOI 10.3390/molecules25245809, PubMed 33317020
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    Sex and age differences in symptoms and signs of dry eye disease in a Norwegian cohort of patients
    Ocul Surf, 19, 68-73
    DOI 10.1016/j.jtos.2020.11.009, PubMed 33246035
  133. Døving M, Galteland P, Eken T, Sehic A, Utheim TP, Skaga NO, Helseth E, Ramm-Pettersen J (2020)
    Dentoalveolar injuries, bicycling accidents and helmet use in patients referred to a Norwegian Trauma Centre: A 12-year prospective study
    Dent Traumatol, 37 (2), 240-246
    DOI 10.1111/edt.12627, PubMed 33220164
  134. Vehof J, Utheim TP, Bootsma H, Hammond CJ (2020)
    Advances, limitations and future perspectives in the diagnosis and management of dry eye in Sjögren's syndrome
    Clin Exp Rheumatol, 38 Suppl 126 (4), 301-309
    PubMed 33025899
  135. Juul JA, Forsaa VA, Utheim TP, Willassen E (2020)
    Scanning Electron Microscopy Observations of Loa loa (Nematoda)
    Case Rep Ophthalmol, 11 (2), 486-492
    DOI 10.1159/000509338, PubMed 32999680
  136. Swift W, Bair JA, Chen W, Li M, Lie S, Li D, Yang M, Shatos MA, Hodges RR, Kolko M, Utheim TP, Scott W, Dartt DA (2020)
    Povidone iodine treatment is deleterious to human ocular surface conjunctival cells in culture
    BMJ Open Ophthalmol, 5 (1), e000545
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  137. Khan AZ, Jackson CJ, Utheim TP, Reppe S, Sapkota D, Olstad OK, Thiede B, Eidet JR (2020)
    Sericin-Induced Melanogenesis in Cultured Retinal Pigment Epithelial Cells Is Associated with Elevated Levels of Hydrogen Peroxide and Inflammatory Proteins
    Molecules, 25 (19)
    DOI 10.3390/molecules25194395, PubMed 32987810
  138. Barabino S, Benitez-Del-Castillo JM, Fuchsluger T, Labetoulle M, Malachkova N, Meloni M, Utheim TP, Rolando M (2020)
    Dry eye disease treatment: the role of tear substitutes, their future, and an updated classification
    Eur Rev Med Pharmacol Sci, 24 (17), 8642-8652
    DOI 10.26355/eurrev_202009_22801, PubMed 32964952
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    Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways
    Cells, 9 (9)
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    The Silk Protein Sericin Promotes Viability of ARPE-19 and Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells in vitro
    Curr Eye Res, 46 (4), 504-514
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  141. Cabral JV, Jackson CJ, Utheim TP, Jirsova K (2020)
    Ex vivo cultivated oral mucosal epithelial cell transplantation for limbal stem cell deficiency: a review
    Stem Cell Res Ther, 11 (1), 301
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    Lacrimal Gland Myoepithelial Cells Are Altered in a Mouse Model of Dry Eye Disease
    Am J Pathol, 190 (10), 2067-2079
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    Slc38a1 Conveys Astroglia-Derived Glutamine into GABAergic Interneurons for Neurotransmitter GABA Synthesis
    Cells, 9 (7)
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    Intense pulsed light treatment in meibomian gland dysfunction: A concise review
    Ocul Surf, 18 (4), 583-594
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    Region of interest and directional analysis of subbasal nerves in wide-area corneal nerve plexus mosaics in type 2 diabetes mellitus
    Sci Rep, 10 (1), 10802
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  146. Jackson CJ, Pasovic L, Raeder S, Sehic A, Roald B, de la Paz MF, Tønseth KA, Utheim TP (2020)
    Optisol-GS Storage of Cultured Human Limbal Epithelial Cells at Ambient Temperature Is Superior to Hypothermic Storage
    Curr Eye Res, 45 (12), 1497-1503
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    Twenty years of endophthalmitis: Incidence, aetiology and clinical outcome
    Acta Ophthalmol, 99 (1), e62-e69
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    Postmenopausal osteoporosis is a musculoskeletal disease with a common genetic trait which responds to strength training: a translational intervention study
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    Maresin 1, a specialized proresolving mediator, stimulates intracellular [Ca2+ ] and secretion in conjunctival goblet cells
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    TFOS European Ambassador meeting: Unmet needs and future scientific and clinical solutions for ocular surface diseases
    Ocul Surf, 18 (4), 936-962
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    Stem cell function is conserved during short-term storage of cultured epidermal cell sheets at 12°C
    PLoS One, 15 (5), e0232270
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    The role of meibography in ocular surface diagnostics: A review
    Ocul Surf, 19, 133-144
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    Temporal redistribution of cap and residual stromal thickness after SMILE
    J Cataract Refract Surg, 46 (10), 1331-1338
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    PAX6 Genotypic and Retinal Phenotypic Characterization in Congenital Aniridia
    Invest Ophthalmol Vis Sci, 61 (5), 14
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  155. Yang M, Lippestad M, Hodges RR, Fjærvoll HK, Fjærvoll KA, Bair JA, Utheim TP, Serhan CN, Dartt DA (2020)
    RvE1 uses the LTB4 receptor BLT1 to increase [Ca2+]i and stimulate mucin secretion in cultured rat and human conjunctival goblet cells
    Ocul Surf, 18 (3), 470-482
    DOI 10.1016/j.jtos.2020.04.011, PubMed 32361084
  156. Jirsova K, Seidler Stangova P, Palos M, Mahelkova G, Kalasova S, Rybickova I, Utheim TP, Vesela V (2020)
    Aberrant HLA-DR expression in the conjunctival epithelium after autologous serum treatment in patients with graft-versus-host disease or Sjögren's syndrome
    PLoS One, 15 (4), e0231473
    DOI 10.1371/journal.pone.0231473, PubMed 32315325
  157. Yu H, Enayati S, Chang K, Cho K, Lee SW, Talib M, Zihlavnikova K, Xie J, Achour H, Fried SI, Utheim TP, Chen DF (2020)
    Noninvasive Electrical Stimulation Improves Photoreceptor Survival and Retinal Function in Mice with Inherited Photoreceptor Degeneration
    Invest Ophthalmol Vis Sci, 61 (4), 5
    DOI 10.1167/iovs.61.4.5, PubMed 32271885
  158. Tashbayev B, Utheim TP, Utheim ØA, Ræder S, Jensen JL, Yazdani M, Lagali N, Vitelli V, Dartt DA, Chen X (2020)
    Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease
    Sci Rep, 10 (1), 5542
    DOI 10.1038/s41598-020-62583-x, PubMed 32218518
  159. Enayati S, Chang K, Achour H, Cho KS, Xu F, Guo S, Z Enayati K, Xie J, Zhao E, Turunen T, Sehic A, Lu L, Utheim TP, Chen DF (2020)
    Electrical Stimulation Induces Retinal Müller Cell Proliferation and Their Progenitor Cell Potential
    Cells, 9 (3)
    DOI 10.3390/cells9030781, PubMed 32210151
  160. Tulek A, Mulic A, Refsholt Stenhagen K, Galtung HK, Saeed M, Utheim TP, Khuu C, Galteland P, Sehic A (2020)
    Dental erosion in mice with impaired salivary gland function
    Acta Odontol Scand, 78 (5), 390-400
    DOI 10.1080/00016357.2020.1734234, PubMed 32141357
  161. Tashbayev B, Garen T, Palm Ø, Chen X, Herlofson BB, Young A, Hove LH, Rykke M, Singh PB, Aqrawi LA, Utheim ØA, Utheim TP, Jensen JL (2020)
    Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study
    Sci Rep, 10 (1), 2063
    DOI 10.1038/s41598-020-59078-0, PubMed 32034249
  162. Utheim TP, Chen X, Fricke O, Bergersen LH, Lagali N (2020)
    Microdot Accumulation in the Anterior Cornea with Aging - Quantitative Analysis with in Vivo Confocal Microscopy
    Curr Eye Res, 45 (9), 1058-1064
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  163. Gautvik KM, Günther CC, Prijatelj V, Medina-Gomez C, Shevroja E, Rad LH, Yazdani M, Lindalen E, Valland H, Gautvik VT, Olstad OK, Holden M, Rivadeneira F, Utheim TP, Reppe S (2020)
    Distinct Subsets of Noncoding RNAs Are Strongly Associated With BMD and Fracture, Studied in Weight-Bearing and Non-Weight-Bearing Human Bone
    J Bone Miner Res, 35 (6), 1065-1076
    DOI 10.1002/jbmr.3974, PubMed 32017184
  164. Jackson CJ, Myklebust Ernø IT, Ringstad H, Tønseth KA, Dartt DA, Utheim TP (2019)
    Simple limbal epithelial transplantation: Current status and future perspectives
    Stem Cells Transl Med, 9 (3), 316-327
    DOI 10.1002/sctm.19-0203, PubMed 31802651
  165. Xiao J, Adil MY, Olafsson J, Chen X, Utheim ØA, Ræder S, Lagali NS, Dartt DA, Utheim TP (2019)
    Diagnostic Test Efficacy of Meibomian Gland Morphology and Function
    Sci Rep, 9 (1), 17345
    DOI 10.1038/s41598-019-54013-4, PubMed 31758085
  166. Lagali N, Wowra B, Fries FN, Latta L, Moslemani K, Utheim TP, Wylegala E, Seitz B, Käsmann-Kellner B (2019)
    Early phenotypic features of aniridia-associated keratopathy and association with PAX6 coding mutations
    Ocul Surf, 18 (1), 130-140
    DOI 10.1016/j.jtos.2019.11.002, PubMed 31734509
  167. Lagali N, Wowra B, Fries FN, Latta L, Moslemani K, Utheim TP, Wylegala E, Seitz B, Käsmann-Kellner B (2019)
    PAX6 Mutational Status Determines Aniridia-Associated Keratopathy Phenotype
    Ophthalmology, 127 (2), 273-275
    DOI 10.1016/j.ophtha.2019.09.034, PubMed 31708273
  168. Yazdani M, Shahdadfar A, Jackson CJ, Utheim TP (2019)
    A Hyaluronan Hydrogel Scaffold for Culture of Human Oral Mucosal Epithelial Cells in Limbal Stem-Cell Therapy
    Bioengineering (Basel), 6 (4)
    DOI 10.3390/bioengineering6040097, PubMed 31652804
  169. Xiao J, Adil MY, Chang K, Yu Z, Yang L, Utheim TP, Chen DF, Cho KS (2019)
    Visual Contrast Sensitivity Correlates to the Retinal Degeneration in Rhodopsin Knockout Mice
    Invest Ophthalmol Vis Sci, 60 (13), 4196-4204
    DOI 10.1167/iovs.19-26966, PubMed 31618423
  170. Landsend ECS, Pedersen HR, Utheim ØA, Rueegg CS, Baraas RC, Lagali N, Bragadóttir R, Moe MC, Utheim TP (2019)
    Characteristics and Utility of Fundus Autofluorescence in Congenital Aniridia Using Scanning Laser Ophthalmoscopy
    Invest Ophthalmol Vis Sci, 60 (13), 4120-4128
    DOI 10.1167/iovs.19-26994, PubMed 31574536
  171. Xiao J, Adil MY, Chen X, Utheim ØA, Ræder S, Tønseth KA, Lagali NS, Dartt DA, Utheim TP (2019)
    Functional and Morphological Evaluation of Meibomian Glands in the Assessment of Meibomian Gland Dysfunction Subtype and Severity
    Am J Ophthalmol, 209, 160-167
    DOI 10.1016/j.ajo.2019.09.005, PubMed 31526799
  172. Ræder S, Klyve P, Utheim TP (2019)
    [Dry eye disease – diagnosis and treatment]
    Tidsskr Nor Laegeforen, 139 (11)
    DOI 10.4045/tidsskr.18.0752, PubMed 31429248
  173. Zhou W, Reinstein DZ, Chen X, Chen S, Xu Y, Utheim TP, Stojanovic A (2019)
    Transepithelial Topography-Guided Ablation Assisted by Epithelial Thickness Mapping for Treatment of Regression After Myopic Refractive Surgery
    J Refract Surg, 35 (8), 525-533
    DOI 10.3928/1081597X-20190730-01, PubMed 31393991
  174. Yazdani M, Elgstøen KBP, Rootwelt H, Shahdadfar A, Utheim ØA, Utheim TP (2019)
    Tear Metabolomics in Dry Eye Disease: A Review
    Int J Mol Sci, 20 (15)
    DOI 10.3390/ijms20153755, PubMed 31374809
  175. Aqrawi LA, Galtung HK, Guerreiro EM, Øvstebø R, Thiede B, Utheim TP, Chen X, Utheim ØA, Palm Ø, Skarstein K, Jensen JL (2019)
    Proteomic and histopathological characterisation of sicca subjects and primary Sjögren's syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
    Arthritis Res Ther, 21 (1), 181
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  176. Pedersen HR, Neitz M, Gilson SJ, Landsend ECS, Utheim ØA, Utheim TP, Baraas RC (2019)
    The Cone Photoreceptor Mosaic in Aniridia: Within-Family Phenotype-Genotype Discordance
    Ophthalmol Retina, 3 (6), 523-534
    DOI 10.1016/j.oret.2019.01.020, PubMed 31174676
  177. Chen X, Aqrawi LA, Utheim TP, Tashbayev B, Utheim ØA, Reppe S, Hove LH, Herlofson BB, Singh PB, Palm Ø, Galtung HK, Jensen JCL (2019)
    Elevated cytokine levels in tears and saliva of patients with primary Sjögren's syndrome correlate with clinical ocular and oral manifestations
    Sci Rep, 9 (1), 7319
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  178. Qureshi T, Sørensen C, Berghuis P, Jensen V, Dobszay MB, Farkas T, Dalen KT, Guo C, Hassel B, Utheim TP, Hvalby Ø, Hafting T, Harkany T, Fyhn M, Chaudhry FA (2019)
    The Glutamine Transporter Slc38a1 Regulates GABAergic Neurotransmission and Synaptic Plasticity
    Cereb Cortex, 29 (12), 5166-5179
    DOI 10.1093/cercor/bhz055, PubMed 31050701
  179. Botten N, Hodges RR, Li D, Bair JA, Shatos MA, Utheim TP, Serhan CN, Dartt DA (2019)
    Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells
    FASEB J, 33 (7), 8468-8478
    DOI 10.1096/fj.201802467R, PubMed 31013438
  180. Yazdani M, Chen X, Tashbayev B, Utheim ØA, Ræder S, Hua Y, Eidet JR, Stojanovic A, Dartt DA, Utheim TP (2019)
    Evaluation of the Ocular Surface Disease Index Questionnaire as a Discriminative Test for Clinical Findings in Dry Eye Disease Patients
    Curr Eye Res, 44 (9), 941-947
    DOI 10.1080/02713683.2019.1604972, PubMed 30955380
  181. Yazdani M, Shahdadfar A, Jackson CJ, Utheim TP (2019)
    Hyaluronan-Based Hydrogel Scaffolds for Limbal Stem Cell Transplantation: A Review
    Cells, 8 (3)
    DOI 10.3390/cells8030245, PubMed 30875861
  182. Utheim OA, Pasovic L, Raeder S, Eidet JR, Fostad IG, Sehic A, Roald B, de la Paz MF, Lyberg T, Dartt DA, Utheim TP (2019)
    Effects of explant size on epithelial outgrowth, thickness, stratification, ultrastructure and phenotype of cultured limbal epithelial cells
    PLoS One, 14 (3), e0212524
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  183. Stadnikova A, Trosan P, Skalicka P, Utheim TP, Jirsova K (2019)
    Interleukin-13 maintains the stemness of conjunctival epithelial cell cultures prepared from human limbal explants
    PLoS One, 14 (2), e0211861
    DOI 10.1371/journal.pone.0211861, PubMed 30742646
  184. Skraastad BK, Knudsen C, Jackson C, Utheim TP, Pripp AH, Tønseth KA (2019)
    Quality of life, patient satisfaction and cosmetic outcome after delayed breast reconstruction using DIEP flap: a 10 years' follow-up survey
    J Plast Surg Hand Surg, 53 (2), 119-124
    DOI 10.1080/2000656X.2018.1562459, PubMed 30654667
  185. Tiedemann D, Mouhammad ZA, Utheim TP, Dartt DA, Heegaard S, Petrovski G, Kolko M (2019)
    Conjunctival Goblet Cells, the Overlooked Cells in Glaucoma Treatment
    J Glaucoma, 28 (4), 325-333
    DOI 10.1097/IJG.0000000000001168, PubMed 30585937
  186. Reppe S, Jackson CJ, Ringstad H, Tønseth KA, Bakke H, Eidet JR, Utheim TP (2018)
    High Throughput Screening of Additives Using Factorial Design to Promote Survival of Stored Cultured Epithelial Sheets
    Stem Cells Int, 2018, 6545876
    DOI 10.1155/2018/6545876, PubMed 30581473
  187. Adil MY, Xiao J, Olafsson J, Chen X, Lagali NS, Ræder S, Utheim ØA, Dartt DA, Utheim TP (2018)
    Meibomian Gland Morphology Is a Sensitive Early Indicator of Meibomian Gland Dysfunction
    Am J Ophthalmol, 200, 16-25
    DOI 10.1016/j.ajo.2018.12.006, PubMed 30578784
  188. Nirvani M, Khuu C, Tulek A, Utheim TP, Sand LP, Snead ML, Sehic A (2018)
    Transcriptomic analysis of MicroRNA expression in enamel-producing cells
    Gene, 688, 193-203
    DOI 10.1016/j.gene.2018.11.089, PubMed 30529249
  189. Kaye R, Botten N, Lippestad M, Li D, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2018)
    Resolvin D1, but not resolvin E1, transactivates the epidermal growth factor receptor to increase intracellular calcium and glycoconjugate secretion in rat and human conjunctival goblet cells
    Exp Eye Res, 180, 53-62
    DOI 10.1016/j.exer.2018.11.018, PubMed 30513286
  190. Thomseth V, Cejvanovic V, Jimenez-Solem E, Poulsen HE, Utheim TP, Andersen JT (2018)
    Exposure to antazoline-naphazoline eye drops during pregnancy and the risk of congenital malformations: a Danish nationwide cohort study
    Acta Ophthalmol, 97 (5), 505-509
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  191. Aqrawi LA, Chen X, Jensen JL, Morthen MK, Thiede B, Utheim ØA, Palm Ø, Tashbayev B, Utheim TP, Galtung HK (2018)
    Severity of clinical dry eye manifestations influences protein expression in tear fluid of patients with primary Sjögren's syndrome
    PLoS One, 13 (10), e0205762
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  192. Lagali NS, Badian RA, Liu X, Feldreich TR, Ärnlöv J, Utheim TP, Dahlin LB, Rolandsson O (2018)
    Dendritic cell maturation in the corneal epithelium with onset of type 2 diabetes is associated with tumor necrosis factor receptor superfamily member 9
    Sci Rep, 8 (1), 14248
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  193. Tulek A, Saeed M, Mulic A, Stenhagen KR, Utheim TP, Galtung HK, Khuu C, Nirvani M, Kristiansen MS, Sehic A (2018)
    New animal model of extrinsic dental erosion-Erosive effect on the mouse molar teeth
    Arch Oral Biol, 96, 137-145
    DOI 10.1016/j.archoralbio.2018.08.013, PubMed 30241000
  194. Lång E, Połeć A, Lång A, Valk M, Blicher P, Rowe AD, Tønseth KA, Jackson CJ, Utheim TP, Janssen LMC, Eriksson J, Bøe SO (2018)
    Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
    Nat Commun, 9 (1), 3665
    DOI 10.1038/s41467-018-05578-7, PubMed 30202009
  195. Yazdani M, Chen X, Tashbayev B, Utheim ØA, Ræder S, Lagali N, Stojanovic A, Dartt DA, Utheim TP (2018)
    Tear Production Levels and Dry Eye Disease Severity in a Large Norwegian Cohort
    Curr Eye Res, 43 (12), 1465-1470
    DOI 10.1080/02713683.2018.1514055, PubMed 30183390
  196. He M, Lippestad M, Li D, Hodges RR, Utheim TP, Dartt DA (2018)
    Activation of the EGF Receptor by Histamine Receptor Subtypes Stimulates Mucin Secretion in Conjunctival Goblet Cells
    Invest Ophthalmol Vis Sci, 59 (8), 3543-3553
    DOI 10.1167/iovs.18-2476, PubMed 30025103
  197. Utheim OA, Lyberg T, Eidet JR, Raeder S, Sehic A, Roald B, Messelt E, de la Paz MF, Dartt DA, Utheim TP (2018)
    Effect of Transportation on Cultured Limbal Epithelial Sheets for Worldwide Treatment of Limbal Stem Cell Deficiency
    Sci Rep, 8 (1), 10502
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  198. Brejchova K, Trosan P, Studeny P, Skalicka P, Utheim TP, Bednar J, Jirsova K (2018)
    Characterization and comparison of human limbal explant cultures grown under defined and xeno-free conditions
    Exp Eye Res, 176, 20-28
    DOI 10.1016/j.exer.2018.06.019, PubMed 29928900
  199. Landsend ECS, Utheim ØA, Pedersen HR, Aass HCD, Lagali N, Dartt DA, Baraas RC, Utheim TP (2018)
    The Level of Inflammatory Tear Cytokines is Elevated in Congenital Aniridia and Associated with Meibomian Gland Dysfunction
    Invest Ophthalmol Vis Sci, 59 (5), 2197-2204
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  200. Pedersen HR, Hagen LA, Landsend ECS, Gilson SJ, Utheim ØA, Utheim TP, Neitz M, Baraas RC (2018)
    Color Vision in Aniridia
    Invest Ophthalmol Vis Sci, 59 (5), 2142-2152
    DOI 10.1167/iovs.17-23047, PubMed 29801149
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    Signaling pathways activated by resolvin E1 to stimulate mucin secretion and increase intracellular Ca2+ in cultured rat conjunctival goblet cells
    Exp Eye Res, 173, 64-72
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  202. Lagali NS, Allgeier S, Guimarães P, Badian RA, Ruggeri A, Köhler B, Utheim TP, Peebo B, Peterson M, Dahlin LB, Rolandsson O (2018)
    Wide-field corneal subbasal nerve plexus mosaics in age-controlled healthy and type 2 diabetes populations
    Sci Data, 5, 180075
    DOI 10.1038/sdata.2018.75, PubMed 29688226
  203. Khan AZ, Utheim TP, Reppe S, Sandvik L, Lyberg T, Roald BB, Ibrahim IB, Eidet JR (2018)
    Cultured Human Retinal Pigment Epithelial (hRPE) Sheets: A Search for Suitable Storage Conditions
    Microsc Microanal, 24 (2), 147-155
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    Improvement of Storage Medium for Cultured Human Retinal Pigment Epithelial Cells Using Factorial Design
    Sci Rep, 8 (1), 5688
    DOI 10.1038/s41598-018-24121-8, PubMed 29632395
  205. Aabel P, Utheim TP, Olstad OK, Rask-Andersen H, Dilley RJ, von Unge M (2018)
    Transcription and microRNA Profiling of Cultured Human Tympanic Membrane Epidermal Keratinocytes
    J Assoc Res Otolaryngol, 19 (3), 243-260
    DOI 10.1007/s10162-018-0660-1, PubMed 29623476
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    Concise Review: Altered Versus Unaltered Amniotic Membrane as a Substrate for Limbal Epithelial Cells
    Stem Cells Transl Med, 7 (5), 415-427
    DOI 10.1002/sctm.17-0257, PubMed 29573222
  207. Landsend ECS, Pedersen HR, Utheim ØA, Xiao J, Adil MY, Tashbayev B, Lagali N, Dartt DA, Baraas RC, Utheim TP (2018)
    Meibomian gland dysfunction and keratopathy are associated with dry eye disease in aniridia
    Br J Ophthalmol, 103 (1), 119-124
    DOI 10.1136/bjophthalmol-2017-310927, PubMed 29519880
  208. Nirvani M, Khuu C, Utheim TP, Sand LP, Sehic A (2017)
    Circadian clock and oral cancer
    Mol Clin Oncol, 8 (2), 219-226
    DOI 10.3892/mco.2017.1518, PubMed 29435282
  209. Guo C, Cho KS, Li Y, Tchedre K, Antolik C, Ma J, Chew J, Utheim TP, Huang XA, Yu H, Malik MTA, Anzak N, Chen DF (2018)
    IGFBPL1 Regulates Axon Growth through IGF-1-mediated Signaling Cascades
    Sci Rep, 8 (1), 2054
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  210. Lagali NS, Allgeier S, Guimarães P, Badian RA, Ruggeri A, Köhler B, Utheim TP, Peebo B, Peterson M, Dahlin LB, Rolandsson O (2017)
    Reduced Corneal Nerve Fiber Density in Type 2 Diabetes by Wide-Area Mosaic Analysis
    Invest Ophthalmol Vis Sci, 58 (14), 6318-6327
    DOI 10.1167/iovs.17-22257, PubMed 29242906
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    Stage-related central corneal epithelial transformation in congenital aniridia-associated keratopathy
    Ocul Surf, 16 (1), 163-172
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    The genetics of congenital aniridia-a guide for the ophthalmologist
    Surv Ophthalmol, 63 (1), 105-113
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  213. Lippestad M, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2017)
    Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways
    Invest Ophthalmol Vis Sci, 58 (11), 4530-4544
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    Meibomian gland features in a Norwegian cohort of patients with primary Sjögren´s syndrome
    PLoS One, 12 (9), e0184284
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    Interdisciplinary, Comprehensive Oral and Ocular Evaluation of Patients with Primary Sjögren's Syndrome
    Sci Rep, 7 (1), 10761
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  216. Jackson CJ, Reppe S, Eidet JR, Eide L, Tønseth KA, Bergersen LH, Dartt DA, Griffith M, Utheim TP (2017)
    Optimization of Storage Temperature for Retention of Undifferentiated Cell Character of Cultured Human Epidermal Cell Sheets
    Sci Rep, 7 (1), 8206
    DOI 10.1038/s41598-017-08586-7, PubMed 28811665
  217. Chen X, Stojanovic A, Xu Y, Zhou W, Raeder S, Enayati S, Utheim TP (2017)
    Medium- to Long-Term Results of Corneal Cross-Linking for Keratoconus Using Phototherapeutic Keratectomy for Epithelial Removal and Partial Stromal Ablation
    J Refract Surg, 33 (7), 488-495
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  218. Jackson CJ, Tønseth KA, Utheim TP (2017)
    Cultured epidermal stem cells in regenerative medicine
    Stem Cell Res Ther, 8 (1), 155
    DOI 10.1186/s13287-017-0587-1, PubMed 28676094
  219. Islam R, Eidet JR, Badian RA, Lippestad M, Messelt E, Griffith M, Dartt DA, Utheim TP (2017)
    Tissue Harvesting Site and Culture Medium Affect Attachment, Growth, and Phenotype of Ex Vivo Expanded Oral Mucosal Epithelial Cells
    Sci Rep, 7 (1), 674
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  220. Fostad IG, Eidet JR, Lagali NS, Dartt DA, Ræder S, Messelt EB, Utheim TP (2017)
    Identification of Objective Morphometric Markers of Xerostomia in the Oral Mucosa Epithelium with In Vivo Confocal Microscopy
    Microsc Microanal, 23 (1), 88-96
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    Identification of potential saliva and tear biomarkers in primary Sjögren's syndrome, utilising the extraction of extracellular vesicles and proteomics analysis
    Arthritis Res Ther, 19 (1), 14
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  222. Nirvani M, Khuu C, Utheim TP, Hollingen HS, Amundsen SF, Sand LP, Sehic A (2016)
    Circadian rhythms and gene expression during mouse molar tooth development
    Acta Odontol Scand, 75 (2), 144-153
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    Artificial Polymeric Scaffolds as Extracellular Matrix Substitutes for Autologous Conjunctival Goblet Cell Expansion
    Invest Ophthalmol Vis Sci, 57 (14), 6134-6146
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  224. Salvanos P, Moe MC, Utheim TP, Bragadóttir R, Kerty E (2018)
    ULTRA-WIDE-FIELD FUNDUS IMAGING IN THE DIAGNOSIS AND FOLLOW-UP OF SUSAC SYNDROME
    Retin Cases Brief Rep, 12 (3), 234-239
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  225. Sehic A, Tulek A, Khuu C, Nirvani M, Sand LP, Utheim TP (2016)
    Regulatory roles of microRNAs in human dental tissues
    Gene, 596, 9-18
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  226. Shatos MA, Hodges RR, Morinaga M, McNay DE, Islam R, Bhattacharya S, Li D, Turpie B, Makarenkova HP, Masli S, Utheim TP, Dartt DA (2016)
    Alteration in cellular turnover and progenitor cell population in lacrimal glands from thrombospondin 1-/- mice, a model of dry eye
    Exp Eye Res, 153, 27-41
    DOI 10.1016/j.exer.2016.09.011, PubMed 27697548
  227. Sehic A, Guo S, Cho KS, Corraya RM, Chen DF, Utheim TP (2016)
    Electrical Stimulation as a Means for Improving Vision
    Am J Pathol, 186 (11), 2783-2797
    DOI 10.1016/j.ajpath.2016.07.017, PubMed 27643530
  228. Chen X, Stojanovic A, Wang X, Liang J, Hu D, Utheim TP (2016)
    Epithelial Thickness Profile Change After Combined Topography-Guided Transepithelial Photorefractive Keratectomy and Corneal Cross-linking in Treatment of Keratoconus
    J Refract Surg, 32 (9), 626-34
    DOI 10.3928/1081597X-20160531-02, PubMed 27598733
  229. Khuu C, Nirvani M, Utheim TP, Sehic A (2016)
    MicroRNAs: Modulators of Tooth Development
    Microrna, 5 (2), 132-139
    DOI 10.2174/2211536605666160706003256, PubMed 27397033
  230. Khan AZ, Utheim TP, Jackson CJ, Reppe S, Lyberg T, Eidet JR (2016)
    Nucleus Morphometry in Cultured Epithelial Cells Correlates with Phenotype
    Microsc Microanal, 22 (3), 612-20
    DOI 10.1017/S1431927616000830, PubMed 27329312
  231. Chen X, Stojanovic A, Simonsen D, Wang X, Liu Y, Utheim TP (2016)
    Topography-Guided Transepithelial Surface Ablation in the Treatment of Moderate to High Astigmatism
    J Refract Surg, 32 (6), 418-25
    DOI 10.3928/1081597X-20160428-01, PubMed 27304606
  232. Pasovic L, Eidet JR, Olstad OK, Chen DF, Lyberg T, Utheim TP (2016)
    Impact of Storage Temperature on the Expression of Cell Survival Genes in Cultured ARPE-19 Cells
    Curr Eye Res, 42 (1), 134-144
    DOI 10.3109/02713683.2016.1145236, PubMed 27259952
  233. Zhou W, Stojanovic A, Utheim TP (2016)
    Assessment of refractive astigmatism and simulated therapeutic refractive surgery strategies in coma-like-aberrations-dominant corneal optics
    Eye Vis (Lond), 3, 13
    DOI 10.1186/s40662-016-0044-8, PubMed 27175371
  234. Utheim TP, Islam R, Fostad IG, Eidet JR, Sehic A, Olstad OK, Dartt DA, Messelt EB, Griffith M, Pasovic L (2016)
    Storage Temperature Alters the Expression of Differentiation-Related Genes in Cultured Oral Keratinocytes
    PLoS One, 11 (3), e0152526
    DOI 10.1371/journal.pone.0152526, PubMed 27023475
  235. Hua Y, Zhang X, Utheim TP, Huang J, Pan C, Tan W, Wang Q (2016)
    Evaluation of Equivalent Keratometry Readings Obtained by Pentacam HR (High Resolution)
    PLoS One, 11 (3), e0150121
    DOI 10.1371/journal.pone.0150121, PubMed 26950834
  236. Eidet JR, Reppe S, Pasovic L, Olstad OK, Lyberg T, Khan AZ, Fostad IG, Chen DF, Utheim TP (2016)
    The Silk-protein Sericin Induces Rapid Melanization of Cultured Primary Human Retinal Pigment Epithelial Cells by Activating the NF-κB Pathway
    Sci Rep, 6, 22671
    DOI 10.1038/srep22671, PubMed 26940175
  237. Utheim TP, Utheim ØA, Khan QE, Sehic A (2016)
    Culture of Oral Mucosal Epithelial Cells for the Purpose of Treating Limbal Stem Cell Deficiency
    J Funct Biomater, 7 (1)
    DOI 10.3390/jfb7010005, PubMed 26938569
  238. Utheim TP, Salvanos P, Utheim ØA, Ræder S, Pasovic L, Olstad OK, de la Paz MF, Sehic A (2016)
    Transcriptome Analysis of Cultured Limbal Epithelial Cells on an Intact Amniotic Membrane following Hypothermic Storage in Optisol-GS
    J Funct Biomater, 7 (1)
    DOI 10.3390/jfb7010004, PubMed 26901233
  239. Eidet JR, Dartt DA, Utheim TP (2015)
    Concise Review: Comparison of Culture Membranes Used for Tissue Engineered Conjunctival Epithelial Equivalents
    J Funct Biomater, 6 (4), 1064-84
    DOI 10.3390/jfb6041064, PubMed 26690486
  240. Kolko M, Vosborg F, Henriksen UL, Hasan-Olive MM, Diget EH, Vohra R, Gurubaran IR, Gjedde A, Mariga ST, Skytt DM, Utheim TP, Storm-Mathisen J, Bergersen LH (2015)
    Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease
    Neurochem Res, 41 (6), 1229-36
    DOI 10.1007/s11064-015-1792-x, PubMed 26677077
  241. Chen X, Stojanovic A, Eidet JR, Utheim TP (2015)
    Corneal collagen cross-linking (CXL) in thin corneas
    Eye Vis (Lond), 2, 15
    DOI 10.1186/s40662-015-0025-3, PubMed 26605368
  242. Parissi M, Randjelovic S, Poletti E, Guimarães P, Ruggeri A, Fragkiskou S, Wihlmark TB, Utheim TP, Lagali N (2016)
    Corneal Nerve Regeneration After Collagen Cross-Linking Treatment of Keratoconus: A 5-Year Longitudinal Study
    JAMA Ophthalmol, 134 (1), 70-8
    DOI 10.1001/jamaophthalmol.2015.4518, PubMed 26562763
  243. Pasovic L, Eidet JR, Brusletto BS, Lyberg T, Utheim TP (2015)
    Effect of Storage Temperature on Key Functions of Cultured Retinal Pigment Epithelial Cells
    J Ophthalmol, 2015, 263756
    DOI 10.1155/2015/263756, PubMed 26448872
  244. Jackson C, Eidet JR, Reppe S, Aass HC, Tønseth KA, Roald B, Lyberg T, Utheim TP (2015)
    Effect of Storage Temperature on the Phenotype of Cultured Epidermal Cells Stored in Xenobiotic-Free Medium
    Curr Eye Res, 41 (6), 757-68
    DOI 10.3109/02713683.2015.1062113, PubMed 26398483
  245. Navaratnam J, Utheim TP, Rajasekhar VK, Shahdadfar A (2015)
    Substrates for Expansion of Corneal Endothelial Cells towards Bioengineering of Human Corneal Endothelium
    J Funct Biomater, 6 (3), 917-45
    DOI 10.3390/jfb6030917, PubMed 26378588
  246. Sehic A, Utheim ØA, Ommundsen K, Utheim TP (2015)
    Pre-Clinical Cell-Based Therapy for Limbal Stem Cell Deficiency
    J Funct Biomater, 6 (3), 863-88
    DOI 10.3390/jfb6030863, PubMed 26343740
  247. Lagali N, Poletti E, Patel DV, McGhee CN, Hamrah P, Kheirkhah A, Tavakoli M, Petropoulos IN, Malik RA, Utheim TP, Zhivov A, Stachs O, Falke K, Peschel S, Guthoff R, Chao C, Golebiowski B, Stapleton F, Ruggeri A (2015)
    Focused Tortuosity Definitions Based on Expert Clinical Assessment of Corneal Subbasal Nerves
    Invest Ophthalmol Vis Sci, 56 (9), 5102-9
    DOI 10.1167/iovs.15-17284, PubMed 26241397
  248. Chen X, Stojanovic A, Liu Y, Chen Y, Zhou Y, Utheim TP (2015)
    Postoperative Changes in Corneal Epithelial and Stromal Thickness Profiles After Photorefractive Keratectomy in Treatment of Myopia
    J Refract Surg, 31 (7), 446-53
    DOI 10.3928/1081597X-20150623-02, PubMed 26186563
  249. Islam R, Jackson C, Eidet JR, Messelt EB, Corraya RM, Lyberg T, Griffith M, Dartt DA, Utheim TP (2015)
    Effect of Storage Temperature on Structure and Function of Cultured Human Oral Keratinocytes
    PLoS One, 10 (6), e0128306
    DOI 10.1371/journal.pone.0128306, PubMed 26052937
  250. Salvanos P, Utheim TP, Moe MC, Eide N, Bragadόttir R (2015)
    Autofluorescence imaging in the differential diagnosis of optic disc melanocytoma
    Acta Ophthalmol, 93 (5), 476-480
    DOI 10.1111/aos.12725, PubMed 25923254
  251. Hua Y, Stojanovic A, Utheim TP, Chen X, Ræder S, Huang J, Wang Q (2015)
    Keratometric index obtained by Fourier-domain optical coherence tomography
    PLoS One, 10 (4), e0122441
    DOI 10.1371/journal.pone.0122441, PubMed 25886489
  252. Utheim TP (2015)
    Concise review: transplantation of cultured oral mucosal epithelial cells for treating limbal stem cell deficiency-current status and future perspectives
    Stem Cells, 33 (6), 1685-95
    DOI 10.1002/stem.1999, PubMed 25786664
  253. Utheim O, Islam R, Lyberg T, Roald B, Eidet JR, de la Paz MF, Dartt DA, Raeder S, Utheim TP (2015)
    Serum-free and xenobiotic-free preservation of cultured human limbal epithelial cells
    PLoS One, 10 (3), e0118517
    DOI 10.1371/journal.pone.0118517, PubMed 25734654
  254. Björkblom B, Eidet JR, Utheim TP, Ulltveit-Moe HF, Raeder S (2015)
    Xenobiotic- and Serum-Free Culture of Oral Mucosal Epithelial Cells on Contact Lenses
    Curr Eye Res, 41 (1), 20-7
    DOI 10.3109/02713683.2015.1004720, PubMed 25658020
  255. Chen X, Stojanovic A, Hua Y, Eidet JR, Hu D, Wang J, Utheim TP (2014)
    Reliability of corneal dynamic scheimpflug analyser measurements in virgin and post-PRK eyes
    PLoS One, 9 (10), e109577
    DOI 10.1371/journal.pone.0109577, PubMed 25302580
  256. Jackson C, Aabel P, Eidet JR, Messelt EB, Lyberg T, von Unge M, Utheim TP (2014)
    Effect of storage temperature on cultured epidermal cell sheets stored in xenobiotic-free medium
    PLoS One, 9 (8), e105808
    DOI 10.1371/journal.pone.0105808, PubMed 25170754
  257. Pasovic L, Eidet JR, Lyberg T, Messelt EB, Aabel P, Utheim TP (2014)
    Antioxidants Improve the Viability of Stored Adult Retinal Pigment Epithelial-19 Cultures
    Ophthalmol Ther, 3 (1-2), 49-61
    DOI 10.1007/s40123-014-0024-9, PubMed 25134496
  258. Stojanovic A, Zhou W, Utheim TP (2014)
    Corneal collagen cross-linking with and without epithelial removal: a contralateral study with 0.5% hypotonic riboflavin solution
    Biomed Res Int, 2014, 619398
    DOI 10.1155/2014/619398, PubMed 25050368
  259. Eidet JR, Pasovic L, Maria R, Jackson CJ, Utheim TP (2014)
    Objective assessment of changes in nuclear morphology and cell distribution following induction of apoptosis
    Diagn Pathol, 9, 92
    DOI 10.1186/1746-1596-9-92, PubMed 24885713
  260. Eidet JR, Utheim ØA, Islam R, Lyberg T, Messelt EB, Dartt DA, Utheim TP (2014)
    The impact of storage temperature on the morphology, viability, cell number and metabolism of cultured human conjunctival epithelium
    Curr Eye Res, 40 (1), 30-9
    DOI 10.3109/02713683.2014.909497, PubMed 24750037
  261. Liu Y, Yang X, Utheim TP, Guo C, Xiao M, Liu Y, Yin Z, Ma J (2013)
    Correlation of cytokine levels and microglial cell infiltration during retinal degeneration in RCS rats
    PLoS One, 8 (12), e82061
    DOI 10.1371/journal.pone.0082061, PubMed 24349184
  262. Pasovic L, Utheim TP, Maria R, Lyberg T, Messelt EB, Aabel P, Chen DF, Chen X, Eidet JR (2013)
    Optimization of Storage Temperature for Cultured ARPE-19 Cells
    J Ophthalmol, 2013, 216359
    DOI 10.1155/2013/216359, PubMed 24251032
  263. Parissi M, Karanis G, Randjelovic S, Germundsson J, Poletti E, Ruggeri A, Utheim TP, Lagali N (2013)
    Standardized baseline human corneal subbasal nerve density for clinical investigations with laser-scanning in vivo confocal microscopy
    Invest Ophthalmol Vis Sci, 54 (10), 7091-102
    DOI 10.1167/iovs.13-12999, PubMed 24084094
  264. Engelsvold DH, Utheim TP, Olstad OK, Gonzalez P, Eidet JR, Lyberg T, Trøseid AM, Dartt DA, Raeder S (2013)
    miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium
    Exp Eye Res, 115, 189-98
    DOI 10.1016/j.exer.2013.07.003, PubMed 23872359
  265. Lagali N, Edén U, Utheim TP, Chen X, Riise R, Dellby A, Fagerholm P (2013)
    In vivo morphology of the limbal palisades of vogt correlates with progressive stem cell deficiency in aniridia-related keratopathy
    Invest Ophthalmol Vis Sci, 54 (8), 5333-42
    DOI 10.1167/iovs.13-11780, PubMed 23860752
  266. Edén U, Lagali N, Dellby A, Utheim TP, Riise R, Chen X, Fagerholm P (2013)
    Cataract development in Norwegian patients with congenital aniridia
    Acta Ophthalmol, 92 (2), e165-7
    DOI 10.1111/aos.12225, PubMed 23826968
  267. Stojanovic A, Chen S, Chen X, Stojanovic F, Zhang J, Zhang T, Utheim TP (2013)
    One-step transepithelial topography-guided ablation in the treatment of myopic astigmatism
    PLoS One, 8 (6), e66618
    DOI 10.1371/journal.pone.0066618, PubMed 23799124
  268. Utheim TP, Lyberg T, Ræder S (2013)
    The culture of limbal epithelial cells
    Methods Mol Biol, 1014, 103-29
    DOI 10.1007/978-1-62703-432-6_7, PubMed 23690008
  269. Utheim TP (2013)
    Limbal epithelial cell therapy: past, present, and future
    Methods Mol Biol, 1014, 3-43
    DOI 10.1007/978-1-62703-432-6_1, PubMed 23690002
  270. Fostad IG, Eidet JR, Shatos MA, Utheim TP, Utheim OA, Raeder S, Dartt DA (2012)
    Biopsy harvesting site and distance from the explant affect conjunctival epithelial phenotype ex vivo
    Exp Eye Res, 104, 15-25
    DOI 10.1016/j.exer.2012.09.007, PubMed 23022405
  271. Stojanovic A, Chen X, Jin N, Zhang T, Stojanovic F, Raeder S, Utheim TP (2012)
    Safety and efficacy of epithelium-on corneal collagen cross-linking using a multifactorial approach to achieve proper stromal riboflavin saturation
    J Ophthalmol, 2012, 498435
    DOI 10.1155/2012/498435, PubMed 22900147
  272. Eidet JR, Fostad IG, Shatos MA, Utheim TP, Utheim ØA, Raeder S, Dartt DA (2012)
    Effect of biopsy location and size on proliferative capacity of ex vivo expanded conjunctival tissue
    Invest Ophthalmol Vis Sci, 53 (6), 2897-903
    DOI 10.1167/iovs.11-8269, PubMed 22491407
  273. Chen X, Stojanovic A, Stojanovic F, Eidet JR, Raeder S, Øritsland H, Utheim TP (2012)
    Effect of limbal marking prior to laser ablation on the magnitude of cyclotorsional error
    J Refract Surg, 28 (5), 358-62
    DOI 10.3928/1081597X-20120221-02, PubMed 22421093
  274. Eidet JR, Utheim OA, Raeder S, Dartt DA, Lyberg T, Carreras E, Huynh TT, Messelt EB, Louch WE, Roald B, Utheim TP (2011)
    Effects of serum-free storage on morphology, phenotype, and viability of ex vivo cultured human conjunctival epithelium
    Exp Eye Res, 94 (1), 109-16
    DOI 10.1016/j.exer.2011.11.015, PubMed 22154551
  275. Chen X, Stojanovic A, Zhou W, Utheim TP, Stojanovic F, Wang Q (2011)
    Transepithelial, Topography-guided Ablation in the Treatment of Visual Disturbances in LASIK Flap or Interface Complications
    J Refract Surg, 28 (2), 120-6
    DOI 10.3928/1081597X-20110926-01, PubMed 21974725
  276. Raeder S, Utheim TP, Messelt E, Lyberg T (2010)
    The impact of de-epithelialization of the amniotic membrane matrix on morphology of cultured human limbal epithelial cells subject to eye bank storage
    Cornea, 29 (4), 439-45
    DOI 10.1097/ICO.0b013e3181ba0c94, PubMed 20164752
  277. Utheim TP, Raeder S, Olstad OK, Utheim ØA, de La Paz M, Cheng R, Huynh TT, Messelt E, Roald B, Lyberg T (2009)
    Comparison of the histology, gene expression profile, and phenotype of cultured human limbal epithelial cells from different limbal regions
    Invest Ophthalmol Vis Sci, 50 (11), 5165-72
    DOI 10.1167/iovs.08-2884, PubMed 19578011
  278. Utheim TP, Raeder S, Utheim ØA, de la Paz M, Roald B, Lyberg T (2009)
    Sterility control and long-term eye-bank storage of cultured human limbal epithelial cells for transplantation
    Br J Ophthalmol, 93 (7), 980-3
    DOI 10.1136/bjo.2008.149591, PubMed 19211610
  279. Utheim ØA, Ritland JS, Utheim TP, Espeseth T, Lydersen S, Rootwelt H, Semb SO, Elsås T (2008)
    Apolipoprotein E genotype and risk for development of cataract and age-related macular degeneration
    Acta Ophthalmol, 86 (4), 401-3
    DOI 10.1111/j.1600-0420.2007.01070.x, PubMed 18498549
  280. Raeder S, Utheim TP, Utheim OA, Nicolaissen B, Roald B, Cai Y, Haug K, Kvalheim A, Messelt EB, Drolsum L, Reed JC, Lyberg T (2007)
    Effects of organ culture and Optisol-GS storage on structural integrity, phenotypes, and apoptosis in cultured corneal epithelium
    Invest Ophthalmol Vis Sci, 48 (12), 5484-93
    DOI 10.1167/iovs.07-0494, PubMed 18055796
  281. Ritland JS, Utheim TP, Utheim OA, Espeseth T, Lydersen S, Semb SO, Rootwelt H, Elsås T (2007)
    Effects of APOE and CHRNA4 genotypes on retinal nerve fibre layer thickness at the optic disc and on risk for developing exfoliation syndrome
    Acta Ophthalmol Scand, 85 (3), 257-61
    DOI 10.1111/j.1600-0420.2006.00824.x, PubMed 17488453
  282. Raeder S, Utheim TP, Utheim OA, Cai Y, Roald B, Lyberg T, Kjeldsen-Kragh J, Ramstad H, Messelt E, Nicolaissen B (2007)
    Effect of limbal explant orientation on the histology, phenotype, ultrastructure and barrier function of cultured limbal epithelial cells
    Acta Ophthalmol Scand, 85 (4), 377-86
    DOI 10.1111/j.1600-0420.2006.00873.x, PubMed 17263847
  283. Kolko M, Vosborg F, Henriksen UL, Hasan-Olive MM, Diget EH, Vohra R, Gurubaran IRS, Gjedde A, Mariga ST, Skytt DM, Utheim TP, Storm-Mathisen J, Bergersen LH (2016)
    Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease (vol 41, pg 1237, 2016)
    Neurochem. Res., 41 (6), 1237
    DOI 10.1007/s11064-016-1916-y
  284. Utheim T, Havskov J, Ozyazicioglu M, Rodriguez J, Talavera E (2014)
    RTQUAKE, A Real-Time Earthquake Detection System Integrated with SEISAN
    Seismol. Res. Lett., 85 (3), 735-742
    DOI 10.1785/0220130175
  285. Raeder S, Klyve P, Utheim TP (2019)
    Dry eyes - diagnostics and treatment
    Tidsskr. Nor. Laegeforen., 139 (11), 1061-1064
  286. Khuu C, Utheim TP, Sehic A (2016)
    The Three Paralogous MicroRNA Clusters in Development and Disease, miR-17-92, miR-106a-363, and miR-106b-25
    Scientifica, 2016, 1379643
    DOI 10.1155/2016/1379643
  287. Vehof J, Utheim TP, Bootsma H, Hammond CJ (2020)
    Advances, limitations and future perspectives in the diagnosis and management of dry eye in Sjogren's syndrome
    Clin. Exp. Rheumatol., 38 (4 126), S301-S309
  288. Fostad IG, Eidet JR, Utheim TP, Raeder S, Lagali NS, Messelt EB, Dartt DA (2016)
    Dry Eye Disease Patients with Xerostomia Report Higher Symptom Load and Have Poorer Meibum Expressibility
    PLoS One, 11 (5), e0155214
    DOI 10.1371/journal.pone.0155214
  289. Khan AZ, Utheim TP, Moe MC, Aass HCD, Sapkota D, Vallenari EM, Eidet JR (2021)
    The Silk Protein Sericin Promotes Viability of ARPE-19 and Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells in vitro
    Curr. Eye Res., 46 (4), 504-514
    DOI 10.1080/02713683.2020.1809001
  290. Stojanovic A, Chen XJ, Zheng LY, Xu YL, Stojanovic F, Utheim TP (2012)
    Late onset post-LASIK keratectasia with reversal and stabilization after use of latanoprost and corneal collagen cross-linking
    Eye Rep., 2 (1), e2-9
    DOI 10.4081/eye.2012.e2

 
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