Christoph Helmstaedter

  • Professor, Senior researcher; Dr. phil.





 

Publications 2024

Bauer T, von Wrede RD, Pujar S, Rácz A, Hoppe C, Baumgartner T, Varadkar S, Held NR, Reiter JT, Enders S, David B, Prillwitz CC, Brugues M, Keil VCW, Jeub M, Borger V, Sander JW, Kunz WS, Radbruch A, Weber B, Helmstaedter C, Vatter H, Baldeweg T, Becker AJ, Cross JH et al. (2024)
Rasmussen's encephalitis: structural, functional, and clinical correlates of contralesional epileptiform activity
J Neurol, 271 (10), 6680-6691
DOI 10.1007/s00415-024-12607-7, PubMed 39138652

Helmstaedter C, Tailby C, Witt JA (2024)
Neuropsychology of late-onset epilepsies
Seizure (in press)
DOI 10.1016/j.seizure.2024.03.010, PubMed 38555201

Reiter JT, Schulte F, Bauer T, David B, Endler C, Isaak A, Schuch F, Bitzer F, Witt JA, Hattingen E, Deichmann R, Attenberger U, Becker AJ, Helmstaedter C, Radbruch A, Surges R, Friedman A, Rüber T (2024)
Evidence for interictal blood-brain barrier dysfunction in people with epilepsy
Epilepsia, 65 (5), 1462-1474
DOI 10.1111/epi.17929, PubMed 38436479

Sanders MW, Van der Wolf I, Jansen FE, Aronica E, Helmstaedter C, Racz A, Surges R, Grote A, Becker AJ, Rheims S, Catenoix H, Duncan JS, De Tisi J, Jacques TS, Cross JH, Kalviainen R, Rauramaa T, Chassoux F, Devaux BC, Di Gennaro G, Esposito V, Bodi I, Honavar M, Bien CG, Cloppenborg T et al. (2024)
Outcome of Epilepsy Surgery in MRI-Negative Patients Without Histopathologic Abnormalities in the Resected Tissue
Neurology, 102 (4), e208007
DOI 10.1212/WNL.0000000000208007, PubMed 38290094

Schneider M, Potthoff AL, Pannicke L, von Arnim CAF, Jessen F, Helmstaedter C (2024)
[ViaCogScreen: An Efficient, Valid, and Repeatable Screening Tool for Cognitive Performance Assessment of the Elderly]
Fortschr Neurol Psychiatr (in press)
DOI 10.1055/a-2276-3557, PubMed 38547902

Schulte F, Reiter JT, Bauer T, Taube J, Bitzer F, Witt JA, Piper R, Thanabalasingam A, von Wrede R, Racz A, Baumgartner T, Borger V, Specht-Riemenschneider L, Vatter H, Hattingen E, Deichmann R, Helmstaedter C, Radbruch A, Friedman A, Surges R, Rüber T (2024)
Interictal blood-brain barrier dysfunction in piriform cortex of people with epilepsy
Ann Clin Transl Neurol (in press)
DOI 10.1002/acn3.52176, PubMed 39190772

Tailby C, Chapman JE, Pugh R, Holth Skogan A, Helmstaedter C, Jackson GD (2024)
Applications of teleneuropsychology to the screening and monitoring of epilepsy
Seizure (in press)
DOI 10.1016/j.seizure.2024.06.022, PubMed 38960770

Tavakol S, Kebets V, Royer J, Li Q, Auer H, DeKraker J, Jefferies E, Bernasconi N, Bernasconi A, Helmstaedter C, Arafat T, Armony J, Nathan Spreng R, Caciagli L, Frauscher B, Smallwood J, Bernhardt B (2024)
Differential relational memory impairment in temporal lobe epilepsy
Epilepsy Behav, 155, 109722
DOI 10.1016/j.yebeh.2024.109722, PubMed 38643660

von Wrede R, Witt JA, Jessen N, Lossius MI, Moskau-Hartmann S, Helmstaedter C (2024)
Screening for depression in patients with epilepsy: What are the benefits for physicians and patients in the real-life setting
Epilepsia (in press)
DOI 10.1111/epi.18089, PubMed 39140982

Witt JA, Moskau-Hartmann S, Olaciregui Dague K, Surges R, Helmstaedter C (2024)
Severe memory decline along with unaffected executive functions under 400 mg/day of cenobamate leading to a collapse in school performance
Neurocase, 30 (3), 91-96
DOI 10.1080/13554794.2024.2366472, PubMed 38869048

Publications 2023

Bauer T, Reiter JT, Enders S, Keil VCW, Radbruch A, Helmstaedter C, Surges R, Rüber T (2023)
Subcortical grey matter volume and asymmetry in the long-term course of Rasmussen's encephalitis
Brain Commun, 5 (6), fcad324
DOI 10.1093/braincomms/fcad324, PubMed 38075946

Fischbach L, Bauer T, Diers K, Witt JA, Brugues M, Borger V, Schidlowski M, Rácz A, Baumgartner T, von Wrede R, Paech D, Weber B, Radbruch A, Vatter H, Becker AJ, Huppertz HJ, Helmstaedter C, Surges R, Reuter M, Rüber T (2023)
A novel geometry-based analysis of hippocampal morphometry in mesial temporal lobe epilepsy
Hum Brain Mapp, 44 (12), 4467-4479
DOI 10.1002/hbm.26392, PubMed 37347650

Grote A, Heiland DH, Taube J, Helmstaedter C, Ravi VM, Will P, Hattingen E, Schüre JR, Witt JA, Reimers A, Elger C, Schramm J, Becker AJ, Delev D (2023)
'Hippocampal innate inflammatory gliosis only' in pharmacoresistant temporal lobe epilepsy
Brain, 146 (2), 549-560
DOI 10.1093/brain/awac293, PubMed 35978480

Harms A, Bauer T, Witt JA, Baumgartner T, von Wrede R, Racz A, Ernst L, Becker AJ, Helmstaedter C, Surges R, Rüber T (2023)
Mesiotemporal Volumetry, Cortical Thickness, and Neuropsychological Deficits in the Long-term Course of Limbic Encephalitis
Neurol Neuroimmunol Neuroinflamm, 10 (4)
DOI 10.1212/NXI.0000000000200125, PubMed 37230543

Hauger LE, Lossius MI, Aaberg KM, Helmstaedter C, Lossius J, Skogan AH (2023)
Screening of attention and executive functions in pediatric patients at a tertiary epilepsy center
Eur J Paediatr Neurol, 46, 35-41
DOI 10.1016/j.ejpn.2023.06.006, PubMed 37418997

Held NR, Bauer T, Reiter JT, Hoppe C, Keil VCW, Radbruch A, Helmstaedter C, Surges R, Rüber T (2023)
Globally altered microstructural properties and network topology in Rasmussen's encephalitis
Brain Commun, 5 (6), fcad290
DOI 10.1093/braincomms/fcad290, PubMed 37953836

Helmstaedter C, Lutz T, Wolf V, Witt JA (2023)
Prevalence of dementia in a level 4 university epilepsy center: how big is the problem?
Front Neurol, 14, 1217594
DOI 10.3389/fneur.2023.1217594, PubMed 37928163

Helmstaedter C, Meschede C, Mastani S, Moskau-Hartmann S, Rademacher M, von Wrede R, Witt JA (2023)
Normalization and cross-sectional validation of an extended Adverse Event Profile (E AEP) in a large cohort of patients with epilepsy
Seizure, 114, 9-17
DOI 10.1016/j.seizure.2023.11.010, PubMed 38029647

Hoppe C, Beeres K, Witt JA, Sassen R, Helmstaedter C (2023)
How are they doing as adults? Psychosocial and socioeconomic outcomes 11-30 years after pediatric epilepsy surgery
Epilepsia Open, 8 (3), 797-810
DOI 10.1002/epi4.12736, PubMed 37003960

Olaciregui Dague K, Witt JA, von Wrede R, Helmstaedter C, Surges R (2023)
DBS of the ANT for refractory epilepsy: A single center experience of seizure reduction, side effects and neuropsychological outcomes
Front Neurol, 14, 1106511
DOI 10.3389/fneur.2023.1106511, PubMed 36970547

von Wrede R, Witt JA, Auvin S, Devlin A, Lagae L, Marson A, Meador KJ, O'Brien TJ, Park J, Surges R, Trinka E, Wiebe S, Helmstaedter C (2023)
Unjustified allegation on cancer risks in children of mothers with epilepsy taking high-dose folic acid during pregnancy-No proof of a causal relationship
Epilepsia, 64 (9), 2239-2243
DOI 10.1111/epi.17680, PubMed 37309815

von Wrede R, Witt JA, Helmstaedter C (2023)
Big Data - Big Trouble: The two faces of publishing results from big data studies based on cohorts with poor clinical definition
Seizure, 111, 21-22
DOI 10.1016/j.seizure.2023.07.015, PubMed 37490829

Witt JA, Becker AJ, Helmstaedter C (2023)
The multifactorial etiology of cognitive deficits in epilepsy and the neuropathology of mesial temporal lobe epilepsy beyond hyperphosphorylated tau
Alzheimers Dement, 19 (7), 3231-3232
DOI 10.1002/alz.13085, PubMed 37070290

Publications 2022

Hansen N, Widman G, Önder D, Schwing K, Leelaarporn P, Prusseit I, von Wrede R, Surges R, Becker AJ, Witt JA, Elger CE, Helmstaedter C (2022)
Increased T- and B-cells associated with the phenotype of autoimmune limbic encephalitis with mainly memory dysfunction
J Transl Autoimmun, 5, 100167
DOI 10.1016/j.jtauto.2022.100167, PubMed 36247087

Harms A, Bauer T, Fischbach L, David B, Ernst L, Witt JA, Diers K, Baumgartner T, Weber B, Radbruch A, Becker AJ, Helmstaedter C, Reuter M, Elger CE, Surges R, Rüber T (2022)
Shape description and volumetry of hippocampus and amygdala in temporal lobe epilepsy - A beneficial combination with a clinical perspective
Epilepsy Behav, 128, 108560
DOI 10.1016/j.yebeh.2022.108560, PubMed 35066389

Helmstaedter C, Rings T, Buscher L, Janssen B, Alaeddin S, Krause V, Knecht S, Lehnertz K (2022)
Stimulation-related modifications of evolving functional brain networks in unresponsive wakefulness
Sci Rep, 12 (1), 11586
DOI 10.1038/s41598-022-15803-5, PubMed 35803974

Henning O, Alfstad KÅ, Johannessen Landmark C, Helmstaedter C, Lossius MI, Holth Skogan A (2022)
Use of screening tools to assess comorbidities and adverse events in patients with epilepsy. A European Reference Network for Rare and Complex Epilepsies (EpiCARE) survey
Seizure, 101, 237-243
DOI 10.1016/j.seizure.2022.09.008, PubMed 36115293

Hoppe C, Beeres K, Witt JA, Sassen R, Helmstaedter C (2022)
Clinical adult outcome 11-30 years after pediatric epilepsy surgery: Complications and other surgical adverse events, seizure control, and cure of epilepsy
Epilepsia, 64 (2), 335-347
DOI 10.1111/epi.17477, PubMed 36468792

Pukropski J, von Wrede R, Helmstaedter C, Surges R (2022)
[Transient epileptic amnesia-A rare phenomenon in temporal lobe epilepsies]
Nervenarzt, 93 (12), 1193-1205
DOI 10.1007/s00115-022-01364-5, PubMed 35920860

Rácz A, Hummel CA, Becker A, Helmstaedter C, Schuch F, Baumgartner T, von Wrede R, Borger V, Solymosi L, Surges R, Elger CE (2022)
Histopathologic Characterization and Neurodegenerative Markers in Patients With Limbic Encephalitis Undergoing Epilepsy Surgery
Front Neurol, 13, 859868
DOI 10.3389/fneur.2022.859868, PubMed 35493848

Reimers A, Helmstaedter C, Elger CE, Pitsch J, Hamed M, Becker AJ, Witt JA (2022)
Neuropathological Insights into Unexpected Cognitive Decline in Epilepsy
Ann Neurol, 93 (3), 536-550
DOI 10.1002/ana.26557, PubMed 36411525

Schach S, Rings T, Bregulla M, Witt JA, Bröhl T, Surges R, von Wrede R, Lehnertz K, Helmstaedter C (2022)
Electrodermal Activity Biofeedback Alters Evolving Functional Brain Networks in People With Epilepsy, but in a Non-specific Manner
Front Neurosci, 16, 828283
DOI 10.3389/fnins.2022.828283, PubMed 35310086

Taube J, Witt JA, Baumgartner T, Helmstaedter C (2022)
All's well that ends well? Long-term course of a patient with anti-amphiphysin associated limbic encephalitis
Epilepsy Behav Rep, 18, 100534
DOI 10.1016/j.ebr.2022.100534, PubMed 35360257

Taube J, Witt JA, Grote A, Delev D, Enkirch J, Hattingen E, Becker AJ, Elger CE, Helmstaedter C (2022)
Preoperative and postoperative memory in epilepsy patients with 'gliosis only' versus hippocampal sclerosis: a matched case-control study
J Neurol Neurosurg Psychiatry (in press)
DOI 10.1136/jnnp-2022-329224, PubMed 36008114

von Wrede R, Bröhl T, Rings T, Pukropski J, Helmstaedter C, Lehnertz K (2022)
Modifications of Functional Human Brain Networks by Transcutaneous Auricular Vagus Nerve Stimulation: Impact of Time of Day
Brain Sci, 12 (5)
DOI 10.3390/brainsci12050546, PubMed 35624933

von Wrede R, Rings T, Bröhl T, Pukropski J, Schach S, Helmstaedter C, Lehnertz K (2022)
Transcutaneous Auricular Vagus Nerve Stimulation Differently Modifies Functional Brain Networks of Subjects With Different Epilepsy Types
Front Hum Neurosci, 16, 867563
DOI 10.3389/fnhum.2022.867563, PubMed 35814953

von Wrede R, Schidlowski M, Huppertz HJ, Rüber T, Ivo A, Baumgartner T, Hallmann K, Zsurka G, Helmstaedter C, Surges R, Kunz WS (2022)
Large Phenotypic Variation of Individuals from a Family with a Novel ASPM Mutation Associated with Microcephaly, Epilepsy, and Behavioral and Cognitive Deficits
Genes (Basel), 13 (3)
DOI 10.3390/genes13030429, PubMed 35327983

Witt JA, Helmstaedter C (2022)
Do executive deficits differentiate between autoimmune temporal lobe epilepsy and temporal lobe epilepsies with non-autoimmune etiologies? A critical view on recently published data
Epilepsy Behav, 129, 108562
DOI 10.1016/j.yebeh.2022.108562, PubMed 35065890

Witt JA, Rademacher M, von Wrede R, Surges R, Helmstaedter C (2022)
Cognitive reawakening and improved quality of life achieved after discontinuing 16 years of anti-seizure treatment with topiramate
Neurocase, 28 (1), 102-106
DOI 10.1080/13554794.2022.2032187, PubMed 35102809

Witt JA, Widman G, Hansen N, von Wrede R, Elger CE, Helmstaedter C (2022)
Evaluation of a Rapid Topiramate Titration Scheme for the Early Detection of Cognitive Side Effects
CNS Drugs, 36 (12), 1325-1330
DOI 10.1007/s40263-022-00969-3, PubMed 36322373

Publications 2021

Dik A, Widman G, Schulte-Mecklenbeck A, Witt JA, Pitsch J, Golombeck KS, Wagner J, Gallus M, Strippel C, Hansen N, Mönig C, Räuber S, Wiendl H, Elger CE, Surges R, Meuth SG, Helmstaedter C, Gross CC, Becker AJ, Melzer N (2021)
Impact of T cells on neurodegeneration in anti-GAD65 limbic encephalitis
Ann Clin Transl Neurol, 8 (12), 2289-2301
DOI 10.1002/acn3.51486, PubMed 34841709

Helmstaedter C, Solymosi L, Kurthen M, Momjian S, Schaller K (2021)
Dr. Strangelove demystified: Disconnection of hand and language dominance explains alien-hand syndrome after corpus callosotomy
Seizure, 86, 147-151
DOI 10.1016/j.seizure.2021.02.013, PubMed 33621826

Kanner AM, Patten A, Ettinger AB, Helmstaedter C, Meador KJ, Malhotra M (2021)
Does a psychiatric history play a role in the development of psychiatric adverse events to perampanel… and to placebo?
Epilepsy Behav, 125, 108380
DOI 10.1016/j.yebeh.2021.108380, PubMed 34735963

Luelsberg F, Krakau S, Chaieb L, Witt JA, von Wrede R, Fell J, Helmstaedter C (2021)
Neuropsychological features of mind wandering in left-, right- and extra temporal lobe epilepsy
Seizure, 95, 50-55
DOI 10.1016/j.seizure.2021.12.013, PubMed 34998088

Nass RD, Taube J, Bauer T, Rüber T, Surges R, Helmstaedter C (2021)
Permanent loss of independence in adult febrile-infection-related epilepsy syndrome survivors: an underestimated and unsolved challenge
Eur J Neurol, 28 (9), 3061-3071
DOI 10.1111/ene.14958, PubMed 34091969

Rácz A, Menne K, Borger V, Hampel KG, Vatter H, Helmstaedter C, Elger CE, Surges R (2021)
Outcome after resective epilepsy surgery in the elderly
J Neurosurg, 136 (6), 1617-1626
DOI 10.3171/2021.4.JNS204013, PubMed 34624859

Rings T, von Wrede R, Bröhl T, Schach S, Helmstaedter C, Lehnertz K (2021)
Impact of Transcutaneous Auricular Vagus Nerve Stimulation on Large-Scale Functional Brain Networks: From Local to Global
Front Physiol, 12, 700261
DOI 10.3389/fphys.2021.700261, PubMed 34489724

Schach S, Surges R, Helmstaedter C (2021)
Visual surround suppression in people with epilepsy correlates with attentional-executive functioning, but not with epilepsy or seizure types
Epilepsy Behav, 121 (Pt A), 108080
DOI 10.1016/j.yebeh.2021.108080, PubMed 34062447

von Wrede R, Helmstaedter C, Surges R (2021)
Cannabidiol in the Treatment of Epilepsy
Clin Drug Investig, 41 (3), 211-220
DOI 10.1007/s40261-021-01003-y, PubMed 33559102

von Wrede R, Meschede C, Brand F, Helmstaedter C (2021)
Levetiracetam, perampanel, and the issue of aggression: A self-report study
Epilepsy Behav, 117, 107806
DOI 10.1016/j.yebeh.2021.107806, PubMed 33621813

von Wrede R, Rings T, Schach S, Helmstaedter C, Lehnertz K (2021)
Transcutaneous auricular vagus nerve stimulation induces stabilizing modifications in large-scale functional brain networks: towards understanding the effects of taVNS in subjects with epilepsy
Sci Rep, 11 (1), 7906
DOI 10.1038/s41598-021-87032-1, PubMed 33846432

Witt JA, Helmstaedter C (2021)
Neuropsychological Evaluations in Limbic Encephalitis
Brain Sci, 11 (5)
DOI 10.3390/brainsci11050576, PubMed 33947002

Witt JA, Helmstaedter C (2021)
The impact of perampanel on cognition: A systematic review of studies employing standardized tests in patients with epilepsy
Seizure, 94, 107-111
DOI 10.1016/j.seizure.2021.12.001, PubMed 34890976

Witt JA, Meschede C, Helmstaedter C (2021)
Hazardous employment of invalid measures for cognitive outcome assessment: You only see what your test can show you
Epilepsy Behav, 117, 107865
DOI 10.1016/j.yebeh.2021.107865, PubMed 33662843

Publications 2020

Bauer T, David B, Ernst L, Becker AJ, Witt JA, Helmstaedter C, Wagner J, Weber B, Elger CE, Surges R, Rüber T (2020)
Structural network topology in limbic encephalitis is associated with amygdala enlargement, memory performance and serostatus
Epilepsia, 61 (10), e140-e145
DOI 10.1111/epi.16691, PubMed 32940355

Bauer T, Ernst L, David B, Becker AJ, Wagner J, Witt JA, Helmstaedter C, Weber B, Hattingen E, Elger CE, Surges R, Rüber T (2020)
Fixel-based analysis links white matter characteristics, serostatus and clinical features in limbic encephalitis
Neuroimage Clin, 27, 102289
DOI 10.1016/j.nicl.2020.102289, PubMed 32623136

Borger V, Schneider M, Taube J, Potthoff AL, Keil VC, Hamed M, Aydin G, Ilic I, Solymosi L, Elger CE, Güresir E, Fimmers R, Schuss P, Helmstaedter C, Surges R, Vatter H (2020)
Resection of piriform cortex predicts seizure freedom in temporal lobe epilepsy
Ann Clin Transl Neurol, 8 (1), 177-189
DOI 10.1002/acn3.51263, PubMed 33263942

Delev D, Taube J, Helmstaedter C, Hakvoort K, Grote A, Clusmann H, von Lehe M (2020)
Surgery for temporal lobe epilepsy in the elderly: Improving quality of life despite cognitive impairment
Seizure, 79, 112-119
DOI 10.1016/j.seizure.2020.05.003, PubMed 32464533

Hansen N, Önder D, Schwing K, Widman G, Leelaarporn P, Prusseit I, Surges R, Becker AJ, Witt JA, Helmstaedter C, Elger CE (2020)
CD19+ B-cells in autoantibody-negative limbic encephalitis
Epilepsy Behav, 106, 107016
DOI 10.1016/j.yebeh.2020.107016, PubMed 32199348

Helmstaedter C, Hansen N, Leelaarporn P, Schwing K, Oender D, Widman G, Racz A, Surges R, Becker A, Witt JA (2020)
Specific B- and T-cell populations are associated with cognition in patients with epilepsy and antibody positive and negative suspected limbic encephalitis
J Neurol, 268 (2), 455-466
DOI 10.1007/s00415-020-10158-1, PubMed 32816110

Helmstaedter C, Sadat-Hossieny Z, Kanner AM, Meador KJ (2020)
Cognitive disorders in epilepsy II: Clinical targets, indications and selection of test instruments
Seizure, 83, 223-231
DOI 10.1016/j.seizure.2020.09.031, PubMed 33172763

Kanner AM, Helmstaedter C, Sadat-Hossieny Z, Meador K (2020)
Cognitive disorders in epilepsy I: Clinical experience, real-world evidence and recommendations
Seizure, 83, 216-222
DOI 10.1016/j.seizure.2020.10.009, PubMed 33127274

Krakau S, Chaieb L, Helmstaedter C, von Wrede R, Fell J (2020)
Reduced past-oriented mind wandering in left compared to right medial temporal lobe epilepsy
Eur J Neurosci, 52 (5), 3411-3418
DOI 10.1111/ejn.14743, PubMed 32302022

Kuehn JC, Meschede C, Helmstaedter C, Surges R, von Wrede R, Hattingen E, Vatter H, Elger CE, Schoch S, Becker AJ, Pitsch J (2020)
Adult-onset temporal lobe epilepsy suspicious for autoimmune pathogenesis: Autoantibody prevalence and clinical correlates
PLoS One, 15 (10), e0241289
DOI 10.1371/journal.pone.0241289, PubMed 33119692

Meschede C, Witt JA, Brömling S, Moskau-Hartmann S, Rademacher M, Surges R, von Wrede R, Helmstaedter C (2020)
Changes in cognition after introduction or withdrawal of zonisamide versus topiramate in epilepsy patients: A retrospective study using Bayes statistics
Epilepsia, 61 (7), 1481-1490
DOI 10.1111/epi.16576, PubMed 32557579

Pitsch J, Kamalizade D, Braun A, Kuehn JC, Gulakova PE, Rüber T, Lubec G, Dietrich D, von Wrede R, Helmstaedter C, Surges R, Elger CE, Hattingen E, Vatter H, Schoch S, Becker AJ (2020)
Drebrin Autoantibodies in Patients with Seizures and Suspected Encephalitis
Ann Neurol, 87 (6), 869-884
DOI 10.1002/ana.25720, PubMed 32196746

Tailby C, Collins AJ, Vaughan DN, Abbott DF, O'Shea M, Helmstaedter C, Jackson GD (2020)
Teleneuropsychology in the time of COVID-19: The experience of The Australian Epilepsy Project
Seizure, 83, 89-97
DOI 10.1016/j.seizure.2020.10.005, PubMed 33120327

von Wrede R, Moskau-Hartmann S, Amarell N, Surges R, Erich Elger C, Helmstaedter C (2020)
Plant derived versus synthetic cannabidiol: Wishes and commitment of epilepsy patients
Seizure, 80, 92-95
DOI 10.1016/j.seizure.2020.06.012, PubMed 32554292

von Wrede R, Moskau-Hartmann S, Baumgartner T, Helmstaedter C, Surges R (2020)
Counseling of people with epilepsy via telemedicine: Experiences at a German tertiary epilepsy center during the COVID-19 pandemic
Epilepsy Behav, 112, 107298
DOI 10.1016/j.yebeh.2020.107298, PubMed 32801068

Witt JA, Meschede C, Helmstaedter C (2020)
Reader response: Antiepileptic drugs are not independently associated with cognitive dysfunction
Neurology, 95 (23), 1069
DOI 10.1212/WNL.0000000000011105, PubMed 33288671

Witt JA, Nass RD, Baumgartner T, von Wrede R, Elger CE, Surges R, Helmstaedter C (2020)
Does the accumulated antiepileptic drug load in chronic epilepsy reflect disease severity?
Epilepsia, 61 (12), 2685-2695
DOI 10.1111/epi.16720, PubMed 33058192

Publications 2019

Baxendale S, Wilson SJ, Baker GA, Barr W, Helmstaedter C, Hermann BP, Langfitt J, Reuner G, Rzezak P, Samson S, Smith ML (2019)
Indications and expectations for neuropsychological assessment in epilepsy surgery in children and adults
Epileptic Disord, 21 (3), 221-234
DOI 10.1684/epd.2019.1065, PubMed 31262718

Baxendale S, Wilson SJ, Baker GA, Barr W, Helmstaedter C, Hermann BP, Langfitt J, Reuner G, Rzezak P, Samson S, Smith ML (2019)
Indications and expectations for neuropsychological assessment in epilepsy surgery in children and adults: Executive summary of the report of the ILAE Neuropsychology Task Force Diagnostic Methods Commission: 2017-2021
Epilepsia, 60 (9), 1794-1796
DOI 10.1111/epi.16309, PubMed 31402443

Baxendale SA, Wilson SJ, Baker GA, Barr W, Helmstaedter C, Hermann BP, Langfitt J, Reuner G, Rzezak P, Samson S, Smith ML (2019)
Ten things every neurologist needs to know about neuropsychological assessments and interventions in people with epilepsy
Eur J Neurol, 27 (2), 215-220
DOI 10.1111/ene.14104, PubMed 31610070

Gliem C, Minnerop M, Roeske S, Gärtner H, Schoene-Bake JC, Adler S, Witt JA, Hoffstaedter F, Schneider-Gold C, Betz RC, Helmstaedter C, Tittgemeyer M, Amunts K, Klockgether T, Weber B, Kornblum C (2019)
Tracking the brain in myotonic dystrophies: A 5-year longitudinal follow-up study
PLoS One, 14 (3), e0213381
DOI 10.1371/journal.pone.0213381, PubMed 30845252

Hansen N, Schwing K, Önder D, Widman G, Leelaarporn P, Prusseit I, Surges R, Melzer N, Gross C, Becker AJ, Witt JA, Elger CE, Helmstaedter C (2019)
Low CSF CD4/CD8+ T-cell proportions are associated with blood-CSF barrier dysfunction in limbic encephalitis
Epilepsy Behav, 102, 106682
DOI 10.1016/j.yebeh.2019.106682, PubMed 31846897

Helmstaedter C, Beeres K, Elger CE, Kuczaty S, Schramm J, Hoppe C (2019)
Cognitive outcome of pediatric epilepsy surgery across ages and different types of surgeries: A monocentric 1-year follow-up study in 306 patients of school age
Seizure, 77, 86-92
DOI 10.1016/j.seizure.2019.07.021, PubMed 31375336

Helmstaedter C, Durch P, Hoppe C, Witt JA (2019)
Is the computerized assessment of psychomotor speed more sensitive to cognitive effects of antiepileptic pharmacotherapy than tests with a focus on higher-order cognitive processing? Implications for the choice of sensitive test parameters
Eur Neuropsychopharmacol, 29 (11), 1273-1281
DOI 10.1016/j.euroneuro.2019.09.010, PubMed 31606304

Helmstaedter C, Witt JA, Hoppe C (2019)
Evaluating the mediating role of executive functions for antiepileptic drugs' effects on IQ in children and adolescents with epilepsy
Epilepsy Behav, 96, 98-103
DOI 10.1016/j.yebeh.2019.04.003, PubMed 31121514

Hoppe C, Porębska I, Beeres K, Sassen R, Kuczaty S, Gleissner U, Lendt M, Elger CE, Helmstaedter C (2019)
Parents' view of the cognitive outcome one year after pediatric epilepsy surgery
Epilepsy Behav, 101 (Pt A), 106552
DOI 10.1016/j.yebeh.2019.106552, PubMed 31698257

Höller Y, Helmstaedter C, Lehnertz K (2019)
Correction to: Quantitative Pharmaco-Electroencephalography in Antiepileptic Drug Research
CNS Drugs, 33 (3), 299
DOI 10.1007/s40263-019-00603-9, PubMed 30806964

Ormond DR, Clusmann H, Sassen R, Hoppe C, Helmstaedter C, Schramm J, Grote A (2019)
Pediatric Temporal Lobe Epilepsy Surgery in Bonn and Review of the Literature
Neurosurgery, 84 (4), 844-856
DOI 10.1093/neuros/nyy125, PubMed 29668992

von Wrede R, Moskau-Hartmann S, Amarell N, Elger CE, Helmstaedter C (2019)
Knowledge, expectations and fears of cannabis use of epilepsy patients at a tertiary epilepsy center
Epilepsy Behav, 99, 106458
DOI 10.1016/j.yebeh.2019.106458, PubMed 31419634

von Wrede R, Moskau-Hartmann S, Rüber T, Helmstaedter C, Surges R (2019)
Sustained seizure freedom with transcutaneous vagal nerve stimulation in drug-resistant epilepsy caused by subcortical band heterotopias
Seizure, 70, 25-26
DOI 10.1016/j.seizure.2019.06.026, PubMed 31238196

Witt JA, Coras R, Becker AJ, Elger CE, Blümcke I, Helmstaedter C (2019)
When does conscious memory become dependent on the hippocampus? The role of memory load and the differential relevance of left hippocampal integrity for short- and long-term aspects of verbal memory performance
Brain Struct Funct, 224 (4), 1599-1607
DOI 10.1007/s00429-019-01857-1, PubMed 30863886

Witt JA, Krutenko T, Gädeke M, Surges R, Elger CE, Helmstaedter C (2019)
Accuracy of expert predictions of seizure freedom after epilepsy surgery
Seizure, 70, 59-62
DOI 10.1016/j.seizure.2019.06.030, PubMed 31280099

Publications 2018

Benjamin CFA, Dhingra I, Li AX, Blumenfeld H, Alkawadri R, Bickel S, Helmstaedter C, Meletti S, Bronen RA, Warfield SK, Peters JM, Reutens D, Połczyńska MM, Hirsch LJ, Spencer DD (2018)
Presurgical language fMRI: Technical practices in epilepsy surgical planning
Hum Brain Mapp, 39 (10), 4032-4042
DOI 10.1002/hbm.24229, PubMed 29962111

Benjamin CFA, Li AX, Blumenfeld H, Constable RT, Alkawadri R, Bickel S, Helmstaedter C, Meletti S, Bronen R, Warfield SK, Peters JM, Reutens D, Połczyńska M, Spencer DD, Hirsch LJ (2018)
Presurgical language fMRI: Clinical practices and patient outcomes in epilepsy surgical planning
Hum Brain Mapp, 39 (7), 2777-2785
DOI 10.1002/hbm.24039, PubMed 29528160

Hansen N, Widman G, Stuff S, Becker AJ, Witt JA, Ahmadzadehfar H, Helmstaedter C, Elger CE (2018)
Cancer frequency detected by positron emission tomography-computed tomography in limbic encephalitis
Epilepsy Behav, 89, 105-111
DOI 10.1016/j.yebeh.2018.09.043, PubMed 30408704

Helmstaedter C, Beghi E, Elger CE, Kälviäinen R, Malmgren K, May TW, Perucca E, Trinka E, Witt JA (2018)
No proof of a causal relationship between antiepileptic drug treatment and incidence of dementia. Comment on: Use of antiepileptic drugs and dementia risk-An analysis of Finnish health register and German health insurance data
Epilepsia, 59 (7), 1303-1306
DOI 10.1111/epi.14432, PubMed 29806877

Helmstaedter C, Beghi E, Elger CE, Kälviäinen R, Malmgren K, May TW, Perucca E, Trinka E, Witt JA (2018)
No Evidence of a Causal Role of Antiepileptic Drug Treatment with Regard to the Development of Dementia
J Am Geriatr Soc, 66 (9), 1850-1852
DOI 10.1111/jgs.15467, PubMed 30094813

Helmstaedter C, Elger CE, Vogt VL (2018)
Cognitive outcomes more than 5 years after temporal lobe epilepsy surgery: Remarkable functional recovery when seizures are controlled
Seizure, 62, 116-123
DOI 10.1016/j.seizure.2018.09.023, PubMed 30359865

Helmstaedter C, Gielen GH, Witt JA (2018)
The immediate and short-term effects of bilateral intrahippocampal depth electrodes on verbal memory
Epilepsia, 59 (6), e78-e84
DOI 10.1111/epi.14019, PubMed 29417555

Helmstaedter C, Winter B, Melzer N, Lohmann H, Witt JA (2018)
Accelerated long-term forgetting in focal epilepsies with special consideration given to patients with diagnosed and suspected limbic encephalitis
Cortex, 110, 58-68
DOI 10.1016/j.cortex.2018.01.003, PubMed 29475601

Hoppe C, Helmstaedter C (2018)
Laser interstitial thermotherapy (LiTT) in pediatric epilepsy surgery
Seizure, 77, 69-75
DOI 10.1016/j.seizure.2018.12.010, PubMed 30591281

Höller Y, Helmstaedter C, Lehnertz K (2018)
Quantitative Pharmaco-Electroencephalography in Antiepileptic Drug Research
CNS Drugs, 32 (9), 839-848
DOI 10.1007/s40263-018-0557-x, PubMed 30151652

Mertens LJ, Witt JA, Helmstaedter C (2018)
Affective and behavioral dysfunction under antiepileptic drugs in epilepsy: Development of a new drug-sensitive screening tool
Epilepsy Behav, 83, 175-180
DOI 10.1016/j.yebeh.2018.03.040, PubMed 29709877

Meschede C, Witt JA, Rademacher M, von Wrede RD, Elger CE, Helmstaedter C (2018)
Evaluating the longer-term cognitive effects of adjunctive perampanel compared to lacosamide in a naturalistic outpatient setting
Seizure, 58, 141-146
DOI 10.1016/j.seizure.2018.04.015, PubMed 29704679

Schmid E, Thomschewski A, Taylor A, Zimmermann G, Kirschner M, Kobulashvili T, Brigo F, Rados M, Helmstaedter C, Braun K, Trinka E, E-PILEPSY consortium (2018)
Diagnostic accuracy of functional magnetic resonance imaging, Wada test, magnetoencephalography, and functional transcranial Doppler sonography for memory and language outcome after epilepsy surgery: A systematic review
Epilepsia, 59 (12), 2305-2317
DOI 10.1111/epi.14588, PubMed 30374948

Seyer F, Witt JA, Taube J, Helmstaedter C (2018)
The efficacy of a short-term multidisciplinary epilepsy program
Epilepsy Behav, 86, 98-101
DOI 10.1016/j.yebeh.2018.06.017, PubMed 30030086

Vogt VL, Witt JA, Delev D, Grote A, von Lehe M, Becker AJ, Schramm J, Elger CE, Helmstaedter C (2018)
Cognitive features and surgical outcome of patients with long-term epilepsy-associated tumors (LEATs) within the temporal lobe
Epilepsy Behav, 88, 25-32
DOI 10.1016/j.yebeh.2018.08.028, PubMed 30212725

Witt JA, Elger CE, Helmstaedter C (2018)
Short-term and longer-term effects of brivaracetam on cognition and behavior in a naturalistic clinical setting-Preliminary data
Seizure, 62, 49-54
DOI 10.1016/j.seizure.2018.09.016, PubMed 30278348

Publications 2017

Blachut B, Hoppe C, Surges R, Elger C, Helmstaedter C (2017)
Subjective seizure counts by epilepsy clinical drug trial participants are not reliable
Epilepsy Behav, 67, 122-127
DOI 10.1016/j.yebeh.2016.10.036, PubMed 28139449

Hansen N, Ernst L, Rüber T, Widman G, Becker AJ, Elger CE, Helmstaedter C (2017)
Pre- and long-term postoperative courses of hippocampus-associated memory impairment in epilepsy patients with antibody-associated limbic encephalitis and selective amygdalohippocampectomy
Epilepsy Behav, 79, 93-99
DOI 10.1016/j.yebeh.2017.10.033, PubMed 29253681

Helmstaedter C, Pandolfo RV, Hoppe C, Witt JA (2017)
Cognitive-behavioral correlates of proxy reports on cognitive capabilities in pediatric patients with epilepsy
Seizure, 51, 193-199
DOI 10.1016/j.seizure.2017.08.016, PubMed 28917203

Helmstaedter C, Witt JA (2017)
Epilepsy and cognition - A bidirectional relationship?
Seizure, 49, 83-89
DOI 10.1016/j.seizure.2017.02.017, PubMed 28284559

Hoppe C, Witt JA, Helmstaedter C, Gasser T, Vatter H, Elger CE (2017)
[Stereotactic laser thermocoagulation in epilepsy surgery]
Nervenarzt, 88 (4), 397-407
DOI 10.1007/s00115-017-0283-5, PubMed 28188403

Hoppe C, Witt JA, Helmstaedter C, Gasser T, Vatter H, Elger CE (2017)
Laser interstitial thermotherapy (LiTT) in epilepsy surgery
Seizure, 48, 45-52
DOI 10.1016/j.seizure.2017.04.002, PubMed 28411414

Vogt VL, Delev D, Grote A, Schramm J, von Lehe M, Elger CE, Witt JA, Helmstaedter C (2017)
Neuropsychological outcome after subtemporal versus transsylvian approach for selective amygdalohippocampectomy in patients with mesial temporal lobe epilepsy: a randomised prospective clinical trial
J Neurol Neurosurg Psychiatry, 89 (10), 1057-1063
DOI 10.1136/jnnp-2017-316311, PubMed 29273691

Vogt VL, Äikiä M, Del Barrio A, Boon P, Borbély C, Bran E, Braun K, Carette E, Clark M, Cross JH, Dimova P, Fabo D, Foroglou N, Francione S, Gersamia A, Gil-Nagel A, Guekht A, Harrison S, Hecimovic H, Heminghyt E, Hirsch E, Javurkova A, Kälviäinen R, Kavan N, Kelemen A et al. (2017)
Current standards of neuropsychological assessment in epilepsy surgery centers across Europe
Epilepsia, 58 (3), 343-355
DOI 10.1111/epi.13646, PubMed 28067423

Witt JA, Helmstaedter C (2017)
Cognition in epilepsy: current clinical issues of interest
Curr Opin Neurol, 30 (2), 174-179
DOI 10.1097/WCO.0000000000000430, PubMed 28118301

Witt JA, Helmstaedter C (2017)
How can we overcome neuropsychological adverse effects of antiepileptic drugs?
Expert Opin Pharmacother, 18 (6), 551-554
DOI 10.1080/14656566.2017.1309025, PubMed 28303728

Witt JA, Hoppe C, Helmstaedter C (2017)
Neuropsychologist's (re-)view: Resective versus ablative amygdalohippocampectomies
Epilepsy Res, 142, 161-166
DOI 10.1016/j.eplepsyres.2017.08.017, PubMed 28890320

Publications 2016

Hansen N, Widman G, Witt JA, Wagner J, Becker AJ, Elger CE, Helmstaedter C (2016)
Seizure control and cognitive improvement via immunotherapy in late onset epilepsy patients with paraneoplastic versus GAD65 autoantibody-associated limbic encephalitis
Epilepsy Behav, 65, 18-24
DOI 10.1016/j.yebeh.2016.10.016, PubMed 27855355

Helmstaedter C, Elger CE, Witt JA (2016)
The effect of quantitative and qualitative antiepileptic drug changes on cognitive recovery after epilepsy surgery
Seizure, 36, 63-69
DOI 10.1016/j.seizure.2016.02.001, PubMed 26954934

Helmstaedter C, Witt JA (2016)
How neuropsychology can improve the care of individual patients with epilepsy. Looking back and into the future
Seizure, 44, 113-120
DOI 10.1016/j.seizure.2016.09.010, PubMed 27789166

Kobulashvili T, Höfler J, Dobesberger J, Ernst F, Ryvlin P, Cross JH, Braun K, Dimova P, Francione S, Hecimovic H, Helmstaedter C, Kimiskidis VK, Lossius MI, Malmgren K, Marusic P, Steinhoff BJ, Boon P, Craiu D, Delanty N, Fabo D, Gil-Nagel A, Guekht A, Hirsch E, Kalviainen R, Mameniskiené R et al. (2016)
Current practices in long-term video-EEG monitoring services: A survey among partners of the E-PILEPSY pilot network of reference for refractory epilepsy and epilepsy surgery
Seizure, 38, 38-45
DOI 10.1016/j.seizure.2016.03.009, PubMed 27104922

Lehnertz K, Dickten H, Porz S, Helmstaedter C, Elger CE (2016)
Predictability of uncontrollable multifocal seizures - towards new treatment options
Sci Rep, 6, 24584
DOI 10.1038/srep24584, PubMed 27091239

Malter MP, Widman G, Galldiks N, Stoecker W, Helmstaedter C, Elger CE, Wagner J (2016)
Suspected new-onset autoimmune temporal lobe epilepsy with amygdala enlargement
Epilepsia, 57 (9), 1485-94
DOI 10.1111/epi.13471, PubMed 27418040

Mouthaan BE, Rados M, Barsi P, Boon P, Carmichael DW, Carrette E, Craiu D, Cross JH, Diehl B, Dimova P, Fabo D, Francione S, Gaskin V, Gil-Nagel A, Grigoreva E, Guekht A, Hirsch E, Hecimovic H, Helmstaedter C, Jung J, Kalviainen R, Kelemen A, Kimiskidis V, Kobulashvili T, Krsek P et al. (2016)
Current use of imaging and electromagnetic source localization procedures in epilepsy surgery centers across Europe
Epilepsia, 57 (5), 770-6
DOI 10.1111/epi.13347, PubMed 27012361

Reuber M, Helmstaedter C, Liao W, Loddenkemper T, Thomas R, Kälviäinen R, Mann M (2016)
The future of medicine will be dark without international collaboration [corrected]
Seizure, 41, 42
DOI 10.1016/j.seizure.2016.07.009, PubMed 27458681

Rosenow F, Bast T, Czech T, Feucht M, Hans VH, Helmstaedter C, Huppertz HJ, Noachtar S, Oltmanns F, Polster T, Seeck M, Trinka E, Wagner K, Strzelczyk A (2016)
Revised version of quality guidelines for presurgical epilepsy evaluation and surgical epilepsy therapy issued by the Austrian, German, and Swiss working group on presurgical epilepsy diagnosis and operative epilepsy treatment
Epilepsia, 57 (8), 1215-20
DOI 10.1111/epi.13449, PubMed 27354263

von Rhein B, Wagner J, Widman G, Malter MP, Elger CE, Helmstaedter C (2016)
Suspected antibody negative autoimmune limbic encephalitis: outcome of immunotherapy
Acta Neurol Scand, 135 (1), 134-141
DOI 10.1111/ane.12575, PubMed 26940288

Wagner J, Schoene-Bake JC, Witt JA, Helmstaedter C, Malter MP, Stoecker W, Probst C, Weber B, Elger CE (2016)
Distinct white matter integrity in glutamic acid decarboxylase and voltage-gated potassium channel-complex antibody-associated limbic encephalitis
Epilepsia, 57 (3), 475-83
DOI 10.1111/epi.13297, PubMed 26749370

Publications 2015

Blachut B, Hoppe C, Surges R, Stahl J, Elger CE, Helmstaedter C (2015)
Counting seizures: The primary outcome measure in epileptology from the patients' perspective
Seizure, 29, 97-103
DOI 10.1016/j.seizure.2015.03.004, PubMed 26076850

Bungenberg J, Surano N, Grote A, Surges R, Pernhorst K, Hofmann A, Schoch S, Helmstaedter C, Becker AJ (2015)
Gene expression variance in hippocampal tissue of temporal lobe epilepsy patients corresponds to differential memory performance
Neurobiol Dis, 86, 121-30
DOI 10.1016/j.nbd.2015.11.011, PubMed 26631617

Grote A, Witt JA, Surges R, von Lehe M, Pieper M, Elger CE, Helmstaedter C, Ormond DR, Schramm J, Delev D (2015)
A second chance--reoperation in patients with failed surgery for intractable epilepsy: long-term outcome, neuropsychology and complications
J Neurol Neurosurg Psychiatry, 87 (4), 379-85
DOI 10.1136/jnnp-2015-310322, PubMed 25855399

Helmstaedter C, Jockwitz C, Witt JA (2015)
Menstrual cycle corrupts reliable and valid assessment of language dominance: Consequences for presurgical evaluation of patients with epilepsy
Seizure, 28, 26-31
DOI 10.1016/j.seizure.2015.02.010, PubMed 25765692

Hoppe C, Feldmann M, Blachut B, Surges R, Elger CE, Helmstaedter C (2015)
Novel techniques for automated seizure registration: Patients' wants and needs
Epilepsy Behav, 52 (Pt A), 1-7
DOI 10.1016/j.yebeh.2015.08.006, PubMed 26366675

Hoppe C, Helmstaedter C, Elger CE (2015)
Vagus nerve stimulation for epilepsy treatment in children
Epilepsia, 56 (2), 323-4
DOI 10.1111/epi.12885, PubMed 25708479

Johnson MR, Shkura K, Langley SR, Delahaye-Duriez A, Srivastava P, Hill WD, Rackham OJ, Davies G, Harris SE, Moreno-Moral A, Rotival M, Speed D, Petrovski S, Katz A, Hayward C, Porteous DJ, Smith BH, Padmanabhan S, Hocking LJ, Starr JM, Liewald DC, Visconti A, Falchi M, Bottolo L, Rossetti T et al. (2015)
Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease
Nat Neurosci, 19 (2), 223-32
DOI 10.1038/nn.4205, PubMed 26691832

Malter MP, Frisch C, Zeitler H, Surges R, Urbach H, Helmstaedter C, Elger CE, Bien CG (2015)
Treatment of immune-mediated temporal lobe epilepsy with GAD antibodies
Seizure, 30, 57-63
DOI 10.1016/j.seizure.2015.05.017, PubMed 26216686

Pohlmann-Eden B, Aldenkamp A, Baker GA, Brandt C, Cendes F, Coras R, Crocker CE, Helmstaedter C, Jones-Gotman M, Kanner AM, Mazarati A, Mula M, Smith ML, Omisade A, Tellez-Zenteno J, Hermann BP (2015)
The relevance of neuropsychiatric symptoms and cognitive problems in new-onset epilepsy - Current knowledge and understanding
Epilepsy Behav, 51, 199-209
DOI 10.1016/j.yebeh.2015.07.005, PubMed 26291774

Reber TP, Do Lam AT, Axmacher N, Elger CE, Helmstaedter C, Henke K, Fell J (2015)
Intracranial EEG correlates of implicit relational inference within the hippocampus
Hippocampus, 26 (1), 54-66
DOI 10.1002/hipo.22490, PubMed 26136107

Samarasekera SR, Helmstaedter C, Reuber M (2015)
Cognitive impairment in adults with epilepsy: The relationship between subjective and objective assessments of cognition
Epilepsy Behav, 52 (Pt A), 9-13
DOI 10.1016/j.yebeh.2015.08.013, PubMed 26398591

Widman G, Golombeck K, Hautzel H, Gross CC, Quesada CM, Witt JA, Rota-Kops E, Ermert J, Greschus S, Surges R, Helmstaedter C, Wiendl H, Melzer N, Elger CE (2015)
Treating a GAD65 Antibody-Associated Limbic Encephalitis with Basiliximab: A Case Study
Front Neurol, 6, 167
DOI 10.3389/fneur.2015.00167, PubMed 26284025

Wilson SJ, Baxendale S, Barr W, Hamed S, Langfitt J, Samson S, Watanabe M, Baker GA, Helmstaedter C, Hermann BP, Smith ML (2015)
Indications and expectations for neuropsychological assessment in routine epilepsy care: Report of the ILAE Neuropsychology Task Force, Diagnostic Methods Commission, 2013-2017
Epilepsia, 56 (5), 674-81
DOI 10.1111/epi.12962, PubMed 25779625

Witt JA, Coras R, Schramm J, Becker AJ, Elger CE, Blümcke I, Helmstaedter C (2015)
Relevance of hippocampal integrity for memory outcome after surgical treatment of mesial temporal lobe epilepsy
J Neurol, 262 (10), 2214-24
DOI 10.1007/s00415-015-7831-3, PubMed 26138541

Witt JA, Elger CE, Helmstaedter C (2015)
Adverse cognitive effects of antiepileptic pharmacotherapy: Each additional drug matters
Eur Neuropsychopharmacol, 25 (11), 1954-9
DOI 10.1016/j.euroneuro.2015.07.027, PubMed 26296280

Witt JA, Helmstaedter C (2015)
Cognition in the early stages of adult epilepsy
Seizure, 26, 65-8
DOI 10.1016/j.seizure.2015.01.018, PubMed 25799904

Witt JA, Vogt VL, Widman G, Langen KJ, Elger CE, Helmstaedter C (2015)
Loss of Autonoetic Awareness of Recent Autobiographical Episodes and Accelerated Long-Term Forgetting in a Patient with Previously Unrecognized Glutamic Acid Decarboxylase Antibody Related Limbic Encephalitis
Front Neurol, 6, 130
DOI 10.3389/fneur.2015.00130, PubMed 26106363

Publications 2014

Frisch C, Helmstaedter C (2014)
Object location performance: detection of functional impairment in right temporal lobe epilepsy
Epilepsy Behav, 35, 28-33
DOI 10.1016/j.yebeh.2014.03.027, PubMed 24792097

Helmstaedter C, Witt JA (2014)
Comments on Ortinski P et al. Cognitive side effects of antiepileptic drugs. Epilepsy & behavior 2004;5(Suppl. 1):S60-65
Epilepsy Behav, 40, 29-31
DOI 10.1016/j.yebeh.2014.09.073, PubMed 25453546

Malmgren K, Rydenhag B, Baxendale S, Thompson PJ, Duncan JS, Shorvon S, Helmstaedter C, Elger CE (2014)
Concerns about bilateral radiosurgical treatment of a patient with bilateral temporal lobe epilepsy
Epilepsia, 55 (4), 623
DOI 10.1111/epi.12542, PubMed 24754227

Malter MP, Frisch C, Schoene-Bake JC, Helmstaedter C, Wandinger KP, Stoecker W, Urbach H, Surges R, Elger CE, Vincent AV, Bien CG (2014)
Outcome of limbic encephalitis with VGKC-complex antibodies: relation to antigenic specificity
J Neurol, 261 (9), 1695-705
DOI 10.1007/s00415-014-7408-6, PubMed 24935858

Rosenow F, Bast T, Czech T, Hans V, Helmstaedter C, Huppertz HJ, Seeck M, Trinka E, Wagner K, Vorstand der Arbeitsgemeinschaft für prächirurgische Epilepsiediagnostik und operative Epilepsietherapie (2014)
[Quality guidelines for presurgical epilepsy diagnosis and operative epilepsy therapy: 1st revised version]
Nervenarzt, 85 (6), 753-6
DOI 10.1007/s00115-014-4070-2, PubMed 24861193

Schneider C, Helmstaedter C, Luders E, Thompson PM, Toga AW, Elger C, Weber B (2014)
Relation of callosal structure to cognitive abilities in temporal lobe epilepsy
Front Neurol, 5, 16
DOI 10.3389/fneur.2014.00016, PubMed 24575078

Vogt VL, Witt JA, Malter MP, Schoene-Bake JC, von Lehe M, Elger CE, Helmstaedter C (2014)
Neuropsychological outcome after epilepsy surgery in patients with bilateral Ammon's horn sclerosis
J Neurosurg, 121 (5), 1247-56
DOI 10.3171/2014.7.JNS132037, PubMed 25192479

Wagner J, Witt JA, Helmstaedter C, Malter MP, Weber B, Elger CE (2014)
Automated volumetry of the mesiotemporal structures in antibody-associated limbic encephalitis
J Neurol Neurosurg Psychiatry, 86 (7), 735-42
DOI 10.1136/jnnp-2014-307875, PubMed 25185210

Witt JA, Helmstaedter C, Elger CE (2014)
Is there evidence of a subordinate role of the hippocampal CA1 field for declarative memory formation?
Brain, 138 (Pt 4), e343
DOI 10.1093/brain/awu303, PubMed 25351741

Witt JA, Werhahn KJ, Krämer G, Ruckes C, Trinka E, Helmstaedter C (2014)
Cognitive-behavioral screening in elderly patients with new-onset epilepsy before treatment
Acta Neurol Scand, 130 (3), 172-7
DOI 10.1111/ane.12260, PubMed 24796793

Publications 2013

Frisch C, Malter MP, Elger CE, Helmstaedter C (2013)
Neuropsychological course of voltage-gated potassium channel and glutamic acid decarboxylase antibody related limbic encephalitis
Eur J Neurol, 20 (9), 1297-304
DOI 10.1111/ene.12186, PubMed 23678940

Helmstaedter C (2013)
Cognitive outcomes of different surgical approaches in temporal lobe epilepsy
Epileptic Disord, 15 (3), 221-39
DOI 10.1684/epd.2013.0587, PubMed 23899718

Helmstaedter C, Aldenkamp AP, Baker GA, Mazarati A, Ryvlin P, Sankar R (2013)
Disentangling the relationship between epilepsy and its behavioral comorbidities - the need for prospective studies in new-onset epilepsies
Epilepsy Behav, 31, 43-7
DOI 10.1016/j.yebeh.2013.11.010, PubMed 24333577

Helmstaedter C, Droege F, Witt JA (2013)
[Assessing activities of daily living in patients with epilepsy]
Fortschr Neurol Psychiatr, 81 (8), 452-8
DOI 10.1055/s-0033-1335993, PubMed 23939558

Helmstaedter C, May TW, von Lehe M, Pfaefflin M, Ebner A, Pannek HW, Elger CE, Stefan H, Schramm J (2013)
Temporal lobe surgery in Germany from 1988 to 2008: diverse trends in etiological subgroups
Eur J Neurol, 21 (6), 827-34
DOI 10.1111/ene.12322, PubMed 24313982

Helmstaedter C, Witt JA (2013)
The longer-term cognitive effects of adjunctive antiepileptic treatment with lacosamide in comparison with lamotrigine and topiramate in a naturalistic outpatient setting
Epilepsy Behav, 26 (2), 182-7
DOI 10.1016/j.yebeh.2012.11.052, PubMed 23318473

Kuhnert MT, Bialonski S, Noennig N, Mai H, Hinrichs H, Helmstaedter C, Lehnertz K (2013)
Incidental and intentional learning of verbal episodic material differentially modifies functional brain networks
PLoS One, 8 (11), e80273
DOI 10.1371/journal.pone.0080273, PubMed 24260362

Malter MP, Tschampa HJ, Helmstaedter C, Urbach H, von Lehe M, Becker A, Clusmann H, Elger CE, Bien CG (2013)
Outcome after epilepsy surgery in patients with MRI features of bilateral ammon's horn sclerosis
Epilepsy Res, 105 (1-2), 150-7
DOI 10.1016/j.eplepsyres.2013.02.003, PubMed 23490659

Pernhorst K, van Loo KM, von Lehe M, Priebe L, Cichon S, Herms S, Hoffmann P, Helmstaedter C, Sander T, Schoch S, Becker AJ (2013)
Rs6295 promoter variants of the serotonin type 1A receptor are differentially activated by c-Jun in vitro and correlate to transcript levels in human epileptic brain tissue
Brain Res, 1499, 136-44
DOI 10.1016/j.brainres.2012.12.045, PubMed 23333373

Roeske S, Filla I, Heim S, Amunts K, Helmstaedter C, Wüllner U, Wagner M, Klockgether T, Minnerop M (2013)
Progressive cognitive dysfunction in spinocerebellar ataxia type 3
Mov Disord, 28 (10), 1435-8
DOI 10.1002/mds.25512, PubMed 23736996

Roeske S, Filla I, Heim S, Amunts K, Helmstaedter C, Wüllner U, Wagner M, Klockgether T, Minnerop M (2013)
Reply to: Cognitive dysfunction in spinocerebellar ataxia type 3: variable topographies and patterns
Mov Disord, 29 (1), 157-8
DOI 10.1002/mds.25755, PubMed 24338591

Witt JA, Alpherts W, Helmstaedter C (2013)
Computerized neuropsychological testing in epilepsy: overview of available tools
Seizure, 22 (6), 416-23
DOI 10.1016/j.seizure.2013.04.004, PubMed 23628168

Witt JA, Coras R, Schramm J, Becker AJ, Elger CE, Blümcke I, Helmstaedter C (2013)
The overall pathological status of the left hippocampus determines preoperative verbal memory performance in left mesial temporal lobe epilepsy
Hippocampus, 24 (4), 446-54
DOI 10.1002/hipo.22238, PubMed 24375772

Witt JA, Elger CE, Helmstaedter C (2013)
Which drug-induced side effects would be tolerated in the prospect of seizure control?
Epilepsy Behav, 29 (1), 141-3
DOI 10.1016/j.yebeh.2013.07.013, PubMed 23969201

Publications 2012

Althausen A, Gleissner U, Hoppe C, Sassen R, Buddewig S, von Lehe M, Schramm J, Elger CE, Helmstaedter C (2012)
Long-term outcome of hemispheric surgery at different ages in 61 epilepsy patients
J Neurol Neurosurg Psychiatry, 84 (5), 529-36
DOI 10.1136/jnnp-2012-303811, PubMed 23268362

Fell J, Staresina BP, Do Lam AT, Widman G, Helmstaedter C, Elger CE, Axmacher N (2012)
Memory modulation by weak synchronous deep brain stimulation: a pilot study
Brain Stimul, 6 (3), 270-3
DOI 10.1016/j.brs.2012.08.001, PubMed 22939277

Helmstaedter C, Mihov Y, Toliat MR, Thiele H, Nuernberg P, Schoch S, Surges R, Elger CE, Kunz WS, Hurlemann R (2012)
Genetic variation in dopaminergic activity is associated with the risk for psychiatric side effects of levetiracetam
Epilepsia, 54 (1), 36-44
DOI 10.1111/j.1528-1167.2012.03603.x, PubMed 22881836

Helmstaedter C, Witt JA (2012)
Multifactorial etiology of interictal behavior in frontal and temporal lobe epilepsy
Epilepsia, 53 (10), 1765-73
DOI 10.1111/j.1528-1167.2012.03602.x, PubMed 22881602

Helmstaedter C, Witt JA (2012)
Clinical neuropsychology in epilepsy: theoretical and practical issues
Handb Clin Neurol, 107, 437-59
DOI 10.1016/B978-0-444-52898-8.00036-7, PubMed 22938988

Mueller CA, Scorzin J, von Lehe M, Fimmers R, Helmstaedter C, Zentner J, Lehmann TN, Meencke HJ, Schulze-Bonhage A, Schramm J (2012)
Seizure outcome 1 year after temporal lobe epilepsy: an analysis of MR volumetric and clinical parameters
Acta Neurochir (Wien), 154 (8), 1327-36
DOI 10.1007/s00701-012-1407-0, PubMed 22722378

von Rhein B, Nelles M, Urbach H, Von Lehe M, Schramm J, Helmstaedter C (2012)
Neuropsychological outcome after selective amygdalohippocampectomy: subtemporal versus transsylvian approach
J Neurol Neurosurg Psychiatry, 83 (9), 887-93
DOI 10.1136/jnnp-2011-302025, PubMed 22773854

Witt JA, Elger CE, Helmstaedter C (2012)
Impaired verbal fluency under topiramate--evidence for synergistic negative effects of epilepsy, topiramate, and polytherapy
Eur J Neurol, 20 (1), 130-7
DOI 10.1111/j.1468-1331.2012.03814.x, PubMed 22827489

Witt JA, Helmstaedter C (2012)
Should cognition be screened in new-onset epilepsies? A study in 247 untreated patients
J Neurol, 259 (8), 1727-31
DOI 10.1007/s00415-012-6526-2, PubMed 22580844

Witt JA, Helmstaedter C (2012)
Monitoring the cognitive effects of antiepileptic pharmacotherapy--approaching the individual patient
Epilepsy Behav, 26 (3), 450-6
DOI 10.1016/j.yebeh.2012.09.015, PubMed 23158809

Publications 2011

Fritz NE, Fell J, Burr W, Axmacher N, Elger CE, Helmstaedter C (2011)
Do surface DC-shifts affect epileptic hippocampal EEG activity?
Epilepsy Res, 95 (1-2), 136-43
DOI 10.1016/j.eplepsyres.2011.03.012, PubMed 21550209

Helmstaedter C, Petzold I, Bien CG (2011)
The cognitive consequence of resecting nonlesional tissues in epilepsy surgery--results from MRI- and histopathology-negative patients with temporal lobe epilepsy
Epilepsia, 52 (8), 1402-8
DOI 10.1111/j.1528-1167.2011.03157.x, PubMed 21740419

Helmstaedter C, Roeske S, Kaaden S, Elger CE, Schramm J (2011)
Hippocampal resection length and memory outcome in selective epilepsy surgery
J Neurol Neurosurg Psychiatry, 82 (12), 1375-81
DOI 10.1136/jnnp.2010.240176, PubMed 21653207

Helmstaedter C, Stefan H, Witt JA (2011)
Quality of life in patients with partial-onset seizures under adjunctive therapy with zonisamide: results from a prospective non-interventional surveillance study
Epileptic Disord, 13 (3), 263-76
DOI 10.1684/epd.2011.0459, PubMed 21914589

Kaaden S, Quesada CM, Urbach H, Koenig R, Weber B, Schramm J, Rudinger G, Helmstaedter C (2011)
Neurodevelopmental disruption in early-onset temporal lobe epilepsy: evidence from a voxel-based morphometry study
Epilepsy Behav, 20 (4), 694-9
DOI 10.1016/j.yebeh.2011.02.020, PubMed 21441071

McDonald CR, Taylor J, Hamberger M, Helmstaedter C, Hermann BP, Schefft B (2011)
Future directions in the neuropsychology of epilepsy
Epilepsy Behav, 22 (1), 69-76
DOI 10.1016/j.yebeh.2011.06.004, PubMed 21795122

Minnerop M, Weber B, Schoene-Bake JC, Roeske S, Mirbach S, Anspach C, Schneider-Gold C, Betz RC, Helmstaedter C, Tittgemeyer M, Klockgether T, Kornblum C (2011)
The brain in myotonic dystrophy 1 and 2: evidence for a predominant white matter disease
Brain, 134 (Pt 12), 3530-46
DOI 10.1093/brain/awr299, PubMed 22131273

Witt JA, Glöckner C, Helmstaedter C (2011)
Extended retention intervals can help to bridge the gap between subjective and objective memory impairment
Seizure, 21 (2), 134-40
DOI 10.1016/j.seizure.2011.10.007, PubMed 22119172

Publications 2010

Centeno M, Thompson PJ, Koepp MJ, Helmstaedter C, Duncan JS (2010)
Memory in frontal lobe epilepsy
Epilepsy Res, 91 (2-3), 123-32
DOI 10.1016/j.eplepsyres.2010.07.017, PubMed 20800996

Fliessbach K, Rogowski S, Hoppe C, Sabel M, Goeppert M, Helmstaedter C, Calabrese P, Schackert G, Tonn JC, Simon M, Schlegel U (2010)
Computer-based assessment of cognitive functions in brain tumor patients
J Neurooncol, 100 (3), 427-37
DOI 10.1007/s11060-010-0194-9, PubMed 20449630

Fliessbach K, Witt JA, Packheiser J, von Lehe M, Elger CE, Helmstaedter C (2010)
Depth-of-processing effects on memory encoding after selective amygdalohippocampectomy
Behav Brain Res, 216 (1), 402-7
DOI 10.1016/j.bbr.2010.08.024, PubMed 20797413

Helmstaedter C, Schoof K, Rossmann T, Reuner G, Karlmeier A, Kurlemann G (2010)
Introduction and first validation of EpiTrack Junior, a screening tool for the assessment of cognitive side effects of antiepileptic medication on attention and executive functions in children and adolescents with epilepsy
Epilepsy Behav, 19 (1), 55-64
DOI 10.1016/j.yebeh.2010.06.042, PubMed 20719571

Helmstaedter C, Witt JA (2010)
Cognitive outcome of antiepileptic treatment with levetiracetam versus carbamazepine monotherapy: a non-interventional surveillance trial
Epilepsy Behav, 18 (1-2), 74-80
DOI 10.1016/j.yebeh.2010.02.011, PubMed 20462801

Hoppe C, Helmstaedter C (2010)
Sensitive and specific neuropsychological assessments of the behavioral effects of epilepsy and its treatment are essential
Epilepsia, 51 (11), 2365-6
DOI 10.1111/j.1528-1167.2010.02717.x, PubMed 21192325

Hoppe C, Witt JA, Helmstaedter C (2010)
Depressed mood should not be regarded as a contraindication to epilepsy surgery
Epilepsy Behav, 17 (4), 574; author reply 575-6
DOI 10.1016/j.yebeh.2010.01.021, PubMed 20181535

Klinke I, Minnerop M, Schmitz-Hübsch T, Hendriks M, Klockgether T, Wüllner U, Helmstaedter C (2010)
Neuropsychological features of patients with spinocerebellar ataxia (SCA) types 1, 2, 3, and 6
Cerebellum, 9 (3), 433-42
DOI 10.1007/s12311-010-0183-8, PubMed 20502998

Malter MP, Helmstaedter C, Urbach H, Vincent A, Bien CG (2010)
Antibodies to glutamic acid decarboxylase define a form of limbic encephalitis
Ann Neurol, 67 (4), 470-8
DOI 10.1002/ana.21917, PubMed 20437582

Publications 2009

Axmacher N, Bialleck KA, Weber B, Helmstaedter C, Elger CE, Fell J (2009)
Working memory representation in atypical language dominance
Hum Brain Mapp, 30 (7), 2032-43
DOI 10.1002/hbm.20645, PubMed 18711708

Frisch C, Hanke J, Kleinerüschkamp S, Röske S, Kaaden S, Elger CE, Schramm J, Yilmazer-Hanke DM, Helmstaedter C (2009)
Positive correlation between the density of neuropeptide y positive neurons in the amygdala and parameters of self-reported anxiety and depression in mesiotemporal lobe epilepsy patients
Biol Psychiatry, 66 (5), 433-40
DOI 10.1016/j.biopsych.2009.03.025, PubMed 19482265

Frisch C, Hüsch K, Angenstein F, Kudin A, Kunz W, Elger CE, Helmstaedter C (2009)
Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat
Epilepsia, 50 (6), 1432-41
DOI 10.1111/j.1528-1167.2008.01943.x, PubMed 19374658

Helmstaedter C, Elger CE (2009)
Chronic temporal lobe epilepsy: a neurodevelopmental or progressively dementing disease?
Brain, 132 (Pt 10), 2822-30
DOI 10.1093/brain/awp182, PubMed 19635728

Helmstaedter C, Wietzke J, Lutz MT (2009)
Unique and shared validity of the "Wechsler logical memory test", the "California verbal learning test", and the "verbal learning and memory test" in patients with epilepsy
Epilepsy Res, 87 (2-3), 203-12
DOI 10.1016/j.eplepsyres.2009.09.002, PubMed 19782537

Helmstaedter C, Witt JA (2009)
[Neuropsychology in epilepsy]
Fortschr Neurol Psychiatr, 77 (11), 639-45
DOI 10.1055/s-0028-1109796, PubMed 19890773

Hoppe C, Fliessbach K, Schlegel U, Elger CE, Helmstaedter C (2009)
NeuroCog FX: computerized screening of cognitive functions in patients with epilepsy
Epilepsy Behav, 16 (2), 298-310
DOI 10.1016/j.yebeh.2009.07.041, PubMed 19733124

Kaaden S, Helmstaedter C (2009)
Age at onset of epilepsy as a determinant of intellectual impairment in temporal lobe epilepsy
Epilepsy Behav, 15 (2), 213-7
DOI 10.1016/j.yebeh.2009.03.027, PubMed 19318136

Mueller CA, Kaaden S, Scorzin J, Urbach H, Fimmers R, Helmstaedter C, Zentner J, Lehmann TN, Schramm J (2009)
Shrinkage of the hippocampal remnant after surgery for temporal lobe epilepsy: impact on seizure and neuropsychological outcomes
Epilepsy Behav, 14 (2), 379-86
DOI 10.1016/j.yebeh.2008.12.003, PubMed 19126435

Wellmer J, Weber C, Mende M, von der Groeben F, Urbach H, Clusmann H, Elger CE, Helmstaedter C (2009)
Multitask electrical stimulation for cortical language mapping: hints for necessity and economic mode of application
Epilepsia, 50 (10), 2267-75
DOI 10.1111/j.1528-1167.2009.02192.x, PubMed 19624716

Witt JA, Helmstaedter C (2009)
[Neuropsychology in epilepsy]
Fortschr Neurol Psychiatr, 77 (12), 691-8
DOI 10.1055/s-0028-1109799, PubMed 19950045

Publications 2008

Axmacher N, Helmstaedter C, Elger CE, Fell J (2008)
Enhancement of neocortical-medial temporal EEG correlations during non-REM sleep
Neural Plast, 2008, 563028
DOI 10.1155/2008/563028, PubMed 18566693

Helmstaedter C, Fritz NE, Kockelmann E, Kosanetzky N, Elger CE (2008)
Positive and negative psychotropic effects of levetiracetam
Epilepsy Behav, 13 (3), 535-41
DOI 10.1016/j.yebeh.2008.05.012, PubMed 18583196

Helmstaedter C, Witt JA (2008)
The effects of levetiracetam on cognition: a non-interventional surveillance study
Epilepsy Behav, 13 (4), 642-9
DOI 10.1016/j.yebeh.2008.07.012, PubMed 18707022

Haag A, Knake S, Hamer HM, Boesebeck F, Freitag H, Schulz R, Baum P, Helmstaedter C, Wellmer J, Urbach H, Hopp P, Mayer T, Hufnagel A, Jokeit H, Lerche H, Uttner I, Meencke HJ, Meierkord H, Pauli E, Runge U, Saar J, Trinka E, Benke T, Vulliemoz S, Wiegand G et al. (2008)
The Wada test in Austrian, Dutch, German, and Swiss epilepsy centers from 2000 to 2005: a review of 1421 procedures
Epilepsy Behav, 13 (1), 83-9
DOI 10.1016/j.yebeh.2008.02.012, PubMed 18358786

Rosburg T, Trautner P, Ludowig E, Helmstaedter C, Bien CG, Elger CE, Boutros NN (2008)
Sensory gating in epilepsy - effects of the lateralization of hippocampal sclerosis
Clin Neurophysiol, 119 (6), 1310-9
DOI 10.1016/j.clinph.2008.02.007, PubMed 18381250

Vannucci M, Pezer N, Helmstaedter C, Schaller K, Viggiano MP, Elger CE, Grunwald T (2008)
Hippocampal response to visual objects is related to visual memory functioning
Neuroreport, 19 (9), 965-8
DOI 10.1097/WNR.0b013e328302c89c, PubMed 18521002

Witt JA, Hollmann K, Helmstaedter C (2008)
The impact of lesions and epilepsy on personality and mood in patients with symptomatic epilepsy: a pre- to postoperative follow-up study
Epilepsy Res, 82 (2-3), 139-46
DOI 10.1016/j.eplepsyres.2008.07.011, PubMed 18771900

Publications 2007

Fell J, Fritz NE, Burr W, Ludowig E, Axmacher N, Elger CE, Helmstaedter C (2007)
Human neocortical and hippocampal near-DC shifts are interconnected
Hippocampus, 17 (6), 413-9
DOI 10.1002/hipo.20285, PubMed 17372976

Gleissner U, Fritz NE, Von Lehe M, Sassen R, Elger CE, Helmstaedter C (2007)
The validity of the Child Behavior Checklist for children with epilepsy
Epilepsy Behav, 12 (2), 276-80
DOI 10.1016/j.yebeh.2007.10.013, PubMed 18065270

Gleissner U, Kuczaty S, Clusmann H, Elger CE, Helmstaedter C (2007)
Neuropsychological results in pediatric patients with epilepsy surgery in the parietal cortex
Epilepsia, 49 (4), 700-4
DOI 10.1111/j.1528-1167.2007.01497.x, PubMed 18177357

Helmstaedter C (2007)
Temporal lobe resection--does the prospect of seizure freedom outweigh the cognitive risks?
Nat Clin Pract Neurol, 4 (2), 66-7
DOI 10.1038/ncpneuro0657, PubMed 17955042

Helmstaedter C (2007)
Cognitive outcome of status epilepticus in adults
Epilepsia, 48 Suppl 8, 85-90
DOI 10.1111/j.1528-1167.2007.01360.x, PubMed 18330010

Helmstaedter C, Richter S, Röske S, Oltmanns F, Schramm J, Lehmann TN (2007)
Differential effects of temporal pole resection with amygdalohippocampectomy versus selective amygdalohippocampectomy on material-specific memory in patients with mesial temporal lobe epilepsy
Epilepsia, 49 (1), 88-97
DOI 10.1111/j.1528-1167.2007.01386.x, PubMed 17941848

Hoppe C, Elger CE, Helmstaedter C (2007)
Long-term memory impairment in patients with focal epilepsy
Epilepsia, 48 Suppl 9, 26-9
DOI 10.1111/j.1528-1167.2007.01397.x, PubMed 18047597

Poepel A, Helmstaedter C, Kockelmann E, Axmacher N, Burr W, Elger CE, Fell J (2007)
Correlation between EEG rhythms during sleep: surface versus mediotemporal EEG
Neuroreport, 18 (8), 837-40
DOI 10.1097/WNR.0b013e3281053c1d, PubMed 17471077

Profitlich T, Hoppe C, Reuber M, Helmstaedter C, Bauer J (2007)
Ictal neuropsychological findings in focal nonconvulsive status epilepticus
Epilepsy Behav, 12 (2), 269-75
DOI 10.1016/j.yebeh.2007.10.011, PubMed 18054288

Weber B, Luders E, Faber J, Richter S, Quesada CM, Urbach H, Thompson PM, Toga AW, Elger CE, Helmstaedter C (2007)
Distinct regional atrophy in the corpus callosum of patients with temporal lobe epilepsy
Brain, 130 (Pt 12), 3149-54
DOI 10.1093/brain/awm186, PubMed 17728360

Westheide J, Helmstaedter C, Elger C, Cooper-Mahkorn D, Sträter B, Maier W, Kühn KU (2007)
Sexuality in male psychiatric inpatients. a descriptive comparison of psychiatric patients, patients with epilepsy and healthy volunteers
Pharmacopsychiatry, 40 (5), 183-90
DOI 10.1055/s-2007-985880, PubMed 17874348

Publications 2006

Fliessbach K, Hoppe C, Schlegel U, Elger CE, Helmstaedter C (2006)
[NeuroCogFX--a computer-based neuropsychological assessment battery for the follow-up examination of neurological patients]
Fortschr Neurol Psychiatr, 74 (11), 643-50
DOI 10.1055/s-2006-932162, PubMed 17103364

Frisch C, Kudin AP, Elger CE, Kunz WS, Helmstaedter C (2006)
Amelioration of water maze performance deficits by topiramate applied during pilocarpine-induced status epilepticus is negatively dose-dependent
Epilepsy Res, 73 (2), 173-80
DOI 10.1016/j.eplepsyres.2006.10.001, PubMed 17084066

Gleissner U, Clusmann H, Sassen R, Elger CE, Helmstaedter C (2006)
Postsurgical outcome in pediatric patients with epilepsy: a comparison of patients with intellectual disabilities, subaverage intelligence, and average-range intelligence
Epilepsia, 47 (2), 406-14
DOI 10.1111/j.1528-1167.2006.00436.x, PubMed 16499768

Gleissner U, Lendt M, Mayer S, Elger CE, Helmstaedter C (2006)
[A new questionnaire for recognizing cognitive problems in children and adolescents]
Nervenarzt, 77 (4), 449-65
DOI 10.1007/s00115-005-2050-2, PubMed 16425050

Grivas A, Schramm J, Kral T, von Lehe M, Helmstaedter C, Elger CE, Clusmann H (2006)
Surgical treatment for refractory temporal lobe epilepsy in the elderly: seizure outcome and neuropsychological sequels compared with a younger cohort
Epilepsia, 47 (8), 1364-72
DOI 10.1111/j.1528-1167.2006.00608.x, PubMed 16922883

Helmstaedter C, Fritz NE, González Pérez PA, Elger CE, Weber B (2006)
Shift-back of right into left hemisphere language dominance after control of epileptic seizures: evidence for epilepsy driven functional cerebral organization
Epilepsy Res, 70 (2-3), 257-62
DOI 10.1016/j.eplepsyres.2006.03.005, PubMed 16624525

Helmstaedter C, Kockelmann E (2006)
Cognitive outcomes in patients with chronic temporal lobe epilepsy
Epilepsia, 47 Suppl 2, 96-8
DOI 10.1111/j.1528-1167.2006.00702.x, PubMed 17105474

Netzer C, Helmstaedter C, Ehrbrecht A, Engels H, Schwanitz G, Urbach H, Schröder R, Weber RG, Kornblum C (2006)
Global brain dysmyelination with above-average verbal skills in 18q- syndrome with a 17 Mb terminal deletion
Acta Neurol Scand, 114 (2), 133-8
DOI 10.1111/j.1600-0404.2006.00626.x, PubMed 16867037

Vannucci M, Grunwald T, Pezer N, Dietl T, Helmstaedter C, Schaller C, Viggiano MP, Elger CE (2006)
Hippocampus proper distinguishes between identified and unidentified real-life visual objects: an intracranial ERP study
Neurosci Lett, 401 (1-2), 165-70
DOI 10.1016/j.neulet.2006.03.008, PubMed 16567041

Publications 2005

Fell J, Fernández G, Lutz MT, Kockelmann E, Burr W, Schaller C, Elger CE, Helmstaedter C (2005)
Rhinal-hippocampal connectivity determines memory formation during sleep
Brain, 129 (Pt 1), 108-14
DOI 10.1093/brain/awh647, PubMed 16251217

Fliessbach K, Helmstaedter C, Urbach H, Althaus A, Pels H, Linnebank M, Juergens A, Glasmacher A, Schmidt-Wolf IG, Klockgether T, Schlegel U (2005)
Neuropsychological outcome after chemotherapy for primary CNS lymphoma: a prospective study
Neurology, 64 (7), 1184-8
DOI 10.1212/01.WNL.0000156350.49336.E2, PubMed 15824344

Fritz N, Glogau S, Hoffmann J, Rademacher M, Elger CE, Helmstaedter C (2005)
Efficacy and cognitive side effects of tiagabine and topiramate in patients with epilepsy
Epilepsy Behav, 6 (3), 373-81
DOI 10.1016/j.yebeh.2005.01.002, PubMed 15820346

Gleissner U, Sassen R, Schramm J, Elger CE, Helmstaedter C (2005)
Greater functional recovery after temporal lobe epilepsy surgery in children
Brain, 128 (Pt 12), 2822-9
DOI 10.1093/brain/awh597, PubMed 16014650

Lutz MT, Helmstaedter C (2005)
EpiTrack: tracking cognitive side effects of medication on attention and executive functions in patients with epilepsy
Epilepsy Behav, 7 (4), 708-14
DOI 10.1016/j.yebeh.2005.08.015, PubMed 16266826

Minnerop M, Joe A, Lutz M, Bauer P, Urbach H, Helmstaedter C, Reinhardt M, Klockgether T, Wüllner U (2005)
Putamen dopamine transporter and glucose metabolism are reduced in SCA17
Ann Neurol, 58 (3), 490-1
DOI 10.1002/ana.20609, PubMed 16130104

Publications 2004

Clusmann H, Kral T, Fackeldey E, Blümcke I, Helmstaedter C, von Oertzen J, Urbach H, Schramm J (2004)
Lesional mesial temporal lobe epilepsy and limited resections: prognostic factors and outcome
J Neurol Neurosurg Psychiatry, 75 (11), 1589-96
DOI 10.1136/jnnp.2003.024208, PubMed 15489392

Dietl T, Urbach H, Helmstaedter C, Staedtgen M, Szentkuti A, Grunwald T, Meyer B, Elger C, Kurthen M (2004)
Persistent severe amnesia due to seizure recurrence after unilateral temporal lobectomy
Epilepsy Behav, 5 (3), 394-400
DOI 10.1016/j.yebeh.2004.01.004, PubMed 15145310

Elger CE, Helmstaedter C, Kurthen M (2004)
Chronic epilepsy and cognition
Lancet Neurol, 3 (11), 663-72
DOI 10.1016/S1474-4422(04)00906-8, PubMed 15488459

Gleissner U, Helmstaedter C, Schramm J, Elger CE (2004)
Memory outcome after selective amygdalohippocampectomy in patients with temporal lobe epilepsy: one-year follow-up
Epilepsia, 45 (8), 960-2
DOI 10.1111/j.0013-9580.2004.42203.x, PubMed 15270763

Glogau S, Ellgring H, Elger CE, Helmstaedter C (2004)
Face and facial expression memory in temporal lobe epilepsy patients: preliminary results
Epilepsy Behav, 5 (1), 106-12
DOI 10.1016/j.yebeh.2003.11.014, PubMed 14751215

Helmstaedter C (2004)
Neuropsychological aspects of epilepsy surgery
Epilepsy Behav, 5 Suppl 1, S45-55
DOI 10.1016/j.yebeh.2003.11.006, PubMed 14725846

Helmstaedter C, Brosch T, Kurthen M, Elger CE (2004)
The impact of sex and language dominance on material-specific memory before and after left temporal lobe surgery
Brain, 127 (Pt 7), 1518-25
DOI 10.1093/brain/awh174, PubMed 15128617

Helmstaedter C, Sonntag-Dillender M, Hoppe C, Elger CE (2004)
Depressed mood and memory impairment in temporal lobe epilepsy as a function of focus lateralization and localization
Epilepsy Behav, 5 (5), 696-701
DOI 10.1016/j.yebeh.2004.06.008, PubMed 15380121

Helmstaedter C, Van Roost D, Clusmann H, Urbach H, Elger CE, Schramm J (2004)
Collateral brain damage, a potential source of cognitive impairment after selective surgery for control of mesial temporal lobe epilepsy
J Neurol Neurosurg Psychiatry, 75 (2), 323-6
PubMed 14742620

Kockelmann E, Elger CE, Helmstaedter C (2004)
Cognitive profile of topiramate as compared with lamotrigine in epilepsy patients on antiepileptic drug polytherapy: relationships to blood serum levels and comedication
Epilepsy Behav, 5 (5), 716-21
DOI 10.1016/j.yebeh.2004.06.017, PubMed 15380124

Lutz MT, Clusmann H, Elger CE, Schramm J, Helmstaedter C (2004)
Neuropsychological outcome after selective amygdalohippocampectomy with transsylvian versus transcortical approach: a randomized prospective clinical trial of surgery for temporal lobe epilepsy
Epilepsia, 45 (7), 809-16
DOI 10.1111/j.0013-9580.2004.54003.x, PubMed 15230706

Reuber M, Andersen B, Elger CE, Helmstaedter C (2004)
Depression and anxiety before and after temporal lobe epilepsy surgery
Seizure, 13 (2), 129-35
DOI 10.1016/s1059-1311(03)00073-6, PubMed 15129842

Publications 2003

Fell J, Staedtgen M, Burr W, Kockelmann E, Helmstaedter C, Schaller C, Elger CE, Fernández G (2003)
Rhinal-hippocampal EEG coherence is reduced during human sleep
Eur J Neurosci, 18 (6), 1711-6
DOI 10.1046/j.1460-9568.2003.02934.x, PubMed 14511350

Fliessbach K, Urbach H, Helmstaedter C, Pels H, Glasmacher A, Kraus JA, Klockgether T, Schmidt-Wolf I, Schlegel U (2003)
Cognitive performance and magnetic resonance imaging findings after high-dose systemic and intraventricular chemotherapy for primary central nervous system lymphoma
Arch Neurol, 60 (4), 563-8
DOI 10.1001/archneur.60.4.563, PubMed 12707070

Gleissner U, Kurthen M, Sassen R, Kuczaty S, Elger CE, Linke DB, Urbach H, Helmstaedter C (2003)
Clinical and neuropsychological characteristics of pediatric epilepsy patients with atypical language dominance
Epilepsy Behav, 4 (6), 746-52
DOI 10.1016/j.yebeh.2003.09.003, PubMed 14698711

Helmstaedter C, Kurthen M, Lux S, Reuber M, Elger CE (2003)
Chronic epilepsy and cognition: a longitudinal study in temporal lobe epilepsy
Ann Neurol, 54 (4), 425-32
DOI 10.1002/ana.10692, PubMed 14520652

Kockelmann E, Elger CE, Helmstaedter C (2003)
Significant improvement in frontal lobe associated neuropsychological functions after withdrawal of topiramate in epilepsy patients
Epilepsy Res, 54 (2-3), 171-8
DOI 10.1016/s0920-1211(03)00078-0, PubMed 12837568

Pels H, Schmidt-Wolf IG, Glasmacher A, Schulz H, Engert A, Diehl V, Zellner A, Schackert G, Reichmann H, Kroschinsky F, Vogt-Schaden M, Egerer G, Bode U, Schaller C, Deckert M, Fimmers R, Helmstaedter C, Atasoy A, Klockgether T, Schlegel U (2003)
Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy
J Clin Oncol, 21 (24), 4489-95
DOI 10.1200/JCO.2003.04.056, PubMed 14597744

Reuber M, Pukrop R, Bauer J, Helmstaedter C, Tessendorf N, Elger CE (2003)
Outcome in psychogenic nonepileptic seizures: 1 to 10-year follow-up in 164 patients
Ann Neurol, 53 (3), 305-11
DOI 10.1002/ana.3000, PubMed 12601698

Reuber M, Qurishi A, Bauer J, Helmstaedter C, Fernandez G, Widman G, Elger CE (2003)
Are there physical risk factors for psychogenic non-epileptic seizures in patients with epilepsy?
Seizure, 12 (8), 561-7
DOI 10.1016/s1059-1311(03)00064-5, PubMed 14630494

Vannucci M, Dietl T, Pezer N, Viggiano MP, Helmstaedter C, Schaller C, Elger CE, Grunwald T (2003)
Hippocampal function and visual object processing in temporal lobe epilepsy
Neuroreport, 14 (11), 1489-92
DOI 10.1097/00001756-200308060-00017, PubMed 12960770

Publications 2002

Clusmann H, Schramm J, Kral T, Helmstaedter C, Ostertun B, Fimmers R, Haun D, Elger CE (2002)
Prognostic factors and outcome after different types of resection for temporal lobe epilepsy
J Neurosurg, 97 (5), 1131-41
DOI 10.3171/jns.2002.97.5.1131, PubMed 12450036

Gleissner U, Helmstaedter C, Elger CE (2002)
Memory reorganization in adult brain: observations in three patients with temporal lobe epilepsy
Epilepsy Res, 48 (3), 229-34
DOI 10.1016/s0920-1211(01)00333-3, PubMed 11904242

Gleissner U, Helmstaedter C, Schramm J, Elger CE (2002)
Memory outcome after selective amygdalohippocampectomy: a study in 140 patients with temporal lobe epilepsy
Epilepsia, 43 (1), 87-95
DOI 10.1046/j.1528-1157.2002.24101.x, PubMed 11879392

Gleissner U, Sassen R, Lendt M, Clusmann H, Elger CE, Helmstaedter C (2002)
Pre- and postoperative verbal memory in pediatric patients with temporal lobe epilepsy
Epilepsy Res, 51 (3), 287-96
DOI 10.1016/s0920-1211(02)00158-4, PubMed 12399079

Helmstaedter C (2002)
Effects of chronic epilepsy on declarative memory systems
Prog Brain Res, 135, 439-53
DOI 10.1016/S0079-6123(02)35041-6, PubMed 12143363

Helmstaedter C, Kurthen M (2002)
Validity of the WADA test
Epilepsy Behav, 3 (6), 562-563
DOI 10.1016/s1525-5050(02)00560-7, PubMed 12609256

Helmstaedter C, Reuber M, Elger CC (2002)
Interaction of cognitive aging and memory deficits related to epilepsy surgery
Ann Neurol, 52 (1), 89-94
DOI 10.1002/ana.10260, PubMed 12112052

Lendt M, Gleissner U, Helmstaedter C, Sassen R, Clusmann H, Elger CE (2002)
Neuropsychological Outcome in Children after Frontal Lobe Epilepsy Surgery
Epilepsy Behav, 3 (1), 51-59
DOI 10.1006/ebeh.2001.0296, PubMed 12609353

Lux S, Kurthen M, Helmstaedter C, Hartje W, Reuber M, Elger CE (2002)
The localizing value of ictal consciousness and its constituent functions: a video-EEG study in patients with focal epilepsy
Brain, 125 (Pt 12), 2691-8
DOI 10.1093/brain/awf276, PubMed 12429596

Reuber M, Fernández G, Bauer J, Helmstaedter C, Elger CE (2002)
Diagnostic delay in psychogenic nonepileptic seizures
Neurology, 58 (3), 493-5
DOI 10.1212/wnl.58.3.493, PubMed 11839862

Reuber M, Fernández G, Helmstaedter C, Qurishi A, Elger CE (2002)
Evidence of brain abnormality in patients with psychogenic nonepileptic seizures
Epilepsy Behav, 3 (3), 249-254
DOI 10.1016/s1525-5050(02)00004-5, PubMed 12662605

Publications 2001

Bien CG, Helmstaedter C, Elger CE (2001)
Is it really Alzheimer's disease?
J Neurol Neurosurg Psychiatry, 71 (3), 416-7
DOI 10.1136/jnnp.71.3.416a, PubMed 11534522

Bien CG, Kurthen M, Baron K, Lux S, Helmstaedter C, Schramm J, Elger CE (2001)
Long-term seizure outcome and antiepileptic drug treatment in surgically treated temporal lobe epilepsy patients: a controlled study
Epilepsia, 42 (11), 1416-21
DOI 10.1046/j.1528-1157.2001.43300.x, PubMed 11879344

Helmstaedter C (2001)
Behavioral Aspects of Frontal Lobe Epilepsy
Epilepsy Behav, 2 (5), 384-395
DOI 10.1006/ebeh.2001.0259, PubMed 12609276

Helmstaedter C, Hoppe C, Elger CE (2001)
Memory alterations during acute high-intensity vagus nerve stimulation
Epilepsy Res, 47 (1-2), 37-42
DOI 10.1016/s0920-1211(01)00291-1, PubMed 11673019

Helmstaedter C, Kurthen M (2001)
Memory and epilepsy: characteristics, course, and influence of drugs and surgery
Curr Opin Neurol, 14 (2), 211-6
DOI 10.1097/00019052-200104000-00013, PubMed 11262738

Hoppe C, Helmstaedter C, Scherrmann J, Elger CE (2001)
Self-Reported Mood Changes following 6 Months of Vagus Nerve Stimulation in Epilepsy Patients
Epilepsy Behav, 2 (4), 335-42
DOI 10.1006/ebeh.2001.0194, PubMed 12609210

Hoppe C, Helmstaedter C, Scherrmann J, Elger CE (2001)
No evidence for cognitive side effects after 6 months of vagus nerve stimulation in epilepsy patients
Epilepsy Behav, 2 (4), 351-6
DOI 10.1006/ebeh.2001.0219, PubMed 12609212

Schlegel U, Pels H, Glasmacher A, Kleinschmidt R, Schmidt-Wolf I, Helmstaedter C, Fliessbach K, Deckert M, Van Roost D, Fimmers R, Bode U, Klockgether T (2001)
Combined systemic and intraventricular chemotherapy in primary CNS lymphoma: a pilot study
J Neurol Neurosurg Psychiatry, 71 (1), 118-22
DOI 10.1136/jnnp.71.1.118, PubMed 11413277

Publications 2000

Beck H, Goussakov IV, Lie A, Helmstaedter C, Elger CE (2000)
Synaptic plasticity in the human dentate gyrus
J Neurosci, 20 (18), 7080-6
DOI 10.1523/JNEUROSCI.20-18-07080.2000, PubMed 10995855

Bien CG, Schulze-Bonhage A, Deckert M, Urbach H, Helmstaedter C, Grunwald T, Schaller C, Elger CE (2000)
Limbic encephalitis not associated with neoplasm as a cause of temporal lobe epilepsy
Neurology, 55 (12), 1823-8
DOI 10.1212/wnl.55.12.1823, PubMed 11134380

Helmstaedter C, Elger CE (2000)
Behavioral markers for self- and other-attribution of memory: a study in patients with temporal lobe epilepsy and healthy volunteers
Epilepsy Res, 41 (3), 235-43
DOI 10.1016/s0920-1211(00)00148-0, PubMed 10962214

Helmstaedter C, Kurthen M, Lux S, Johanson K, Quiske A, Schramm J, Elger CE (2000)
[Temporal lobe epilepsy: longitudinal clinical, neuropsychological and psychosocial follow-up of surgically and conservatively managed patients]
Nervenarzt, 71 (8), 629-42
DOI 10.1007/s001150050639, PubMed 10996913

Lassonde M, Sauerwein HC, Jambaqué I, Smith ML, Helmstaedter C (2000)
Neuropsychology of childhood epilepsy: pre- and postsurgical assessment
Epileptic Disord, 2 (1), 3-13
PubMed 10937165

Lendt M, Helmstaedter C, Kuczaty S, Schramm J, Elger CE (2000)
Behavioural disorders in children with epilepsy: early improvement after surgery
J Neurol Neurosurg Psychiatry, 69 (6), 739-44
DOI 10.1136/jnnp.69.6.739, PubMed 11080225

Quiske A, Helmstaedter C, Lux S, Elger CE (2000)
Depression in patients with temporal lobe epilepsy is related to mesial temporal sclerosis
Epilepsy Res, 39 (2), 121-5
DOI 10.1016/s0920-1211(99)00117-5, PubMed 10759300

Publications 1999

Gleissner U, Johanson K, Helmstaedter C, Elger CE (1999)
Surgical outcome in a group of low-IQ patients with focal epilepsy
Epilepsia, 40 (5), 553-9
DOI 10.1111/j.1528-1157.1999.tb05556.x, PubMed 10386523

Helmstaedter C, Elger CE (1999)
The phantom of progressive dementia in epilepsy
Lancet, 354 (9196), 2133-4
DOI 10.1016/s0140-6736(99)03542-4, PubMed 10609823

Helmstaedter C, Kurthen M, Elger CE (1999)
Sex differences in material-specific cognitive functions related to language dominance: an intracarotid amobarbital study in left temporal lobe epilepsy
Laterality, 4 (1), 51-63
DOI 10.1080/713754322, PubMed 15513104

Lendt M, Helmstaedter C, Elger CE (1999)
Pre- and postoperative neuropsychological profiles in children and adolescents with temporal lobe epilepsy
Epilepsia, 40 (11), 1543-50
DOI 10.1111/j.1528-1157.1999.tb02038.x, PubMed 10565581

Zentner J, Wolf HK, Helmstaedter C, Grunwald T, Aliashkevich AF, Wiestler OD, Elger CE, Schramm J (1999)
Clinical relevance of amygdala sclerosis in temporal lobe epilepsy
J Neurosurg, 91 (1), 59-67
DOI 10.3171/jns.1999.91.1.0059, PubMed 10389881

Publications 1998

Gleissner U, Helmstaedter C, Elger CE (1998)
Right hippocampal contribution to visual memory: a presurgical and postsurgical study in patients with temporal lobe epilepsy
J Neurol Neurosurg Psychiatry, 65 (5), 665-9
DOI 10.1136/jnnp.65.5.665, PubMed 9810934

Gleissner U, Helmstaedter C, Quiske A, Elger CE (1998)
The performance-complaint relationship in patients with epilepsy: a matter of daily demands?
Epilepsy Res, 32 (3), 401-9
DOI 10.1016/s0920-1211(98)00072-2, PubMed 9839780

Grunwald T, Lehnertz K, Heinze HJ, Helmstaedter C, Elger CE (1998)
Verbal novelty detection within the human hippocampus proper
Proc Natl Acad Sci U S A, 95 (6), 3193-7
DOI 10.1073/pnas.95.6.3193, PubMed 9501239

Grunwald T, Lehnertz K, Helmstaedter C, Kutas M, Pezer N, Kurthen M, Van Roost D, Elger CE (1998)
Limbic ERPs predict verbal memory after left-sided hippocampectomy
Neuroreport, 9 (15), 3375-8
DOI 10.1097/00001756-199810260-00007, PubMed 9855283

Helmstaedter C, Elger CE (1998)
Functional plasticity after left anterior temporal lobectomy: reconstitution and compensation of verbal memory functions
Epilepsia, 39 (4), 399-406
DOI 10.1111/j.1528-1157.1998.tb01392.x, PubMed 9578030

Helmstaedter C, Gleibner U, Zentner J, Elger CE (1998)
Neuropsychological consequences of epilepsy surgery in frontal lobe epilepsy
Neuropsychologia, 36 (4), 333-41
DOI 10.1016/s0028-3932(97)00118-8, PubMed 9665644

Helmstaedter C, Gleissner U, Zentner J, Elger CE (1998)
Neuropsychological consequences of epilepsy surgery in frontal lobe epilepsy
Neuropsychologia, 36 (7), 681-9
DOI 10.1016/s0028-3932(97)00134-6, PubMed 9723939

Helmstaedter C, Hauff M, Elger CE (1998)
Ecological validity of list-learning tests and self-reported memory in healthy individuals and those with temporal lobe epilepsy
J Clin Exp Neuropsychol, 20 (3), 365-75
DOI 10.1076/jcen.20.3.365.824, PubMed 9845163

Publications 1997

Bauer J, Helmstaedter C, Elger CE (1997)
Nonconvulsive status epilepticus with generalized 'fast activity'
Seizure, 6 (1), 67-70
DOI 10.1016/s1059-1311(97)80056-8, PubMed 9061827

Elger CE, Grunwald T, Lehnertz K, Kutas M, Helmstaedter C, Brockhaus A, Van Roost D, Heinze HJ (1997)
Human temporal lobe potentials in verbal learning and memory processes
Neuropsychologia, 35 (5), 657-67
DOI 10.1016/s0028-3932(96)00110-8, PubMed 9153028

Fernández G, Hufnagel A, Van Roost D, Helmstaedter C, Wolf HK, Zentner J, Schramm J, Elger CE (1997)
Safety of intrahippocampal depth electrodes for presurgical evaluation of patients with intractable epilepsy
Epilepsia, 38 (8), 922-9
DOI 10.1111/j.1528-1157.1997.tb01258.x, PubMed 9579894

Gleissner U, Helmstaedter C, Kurthen M, Elger CE (1997)
Evidence of very fast memory consolidation: an intracarotid amytal study
Neuroreport, 8 (13), 2893-6
DOI 10.1097/00001756-199709080-00018, PubMed 9376526

Helmstaedter C, Gleissner U, Di Perna M, Elger CE (1997)
Relational verbal memory processing in patients with temporal lobe epilepsy
Cortex, 33 (4), 667-78
DOI 10.1016/s0010-9452(08)70724-x, PubMed 9444468

Helmstaedter C, Grunwald T, Lehnertz K, Gleissner U, Elger CE (1997)
Differential involvement of left temporolateral and temporomesial structures in verbal declarative learning and memory: evidence from temporal lobe epilepsy
Brain Cogn, 35 (1), 110-31
DOI 10.1006/brcg.1997.0930, PubMed 9339305

Helmstaedter C, Kurthen M, Gleissner U, Linke DB, Elger CE (1997)
Natural atypical language dominance and language shifts from the right to the left hemisphere in right hemisphere pathology
Naturwissenschaften, 84 (6), 250-2
DOI 10.1007/s001140050390, PubMed 9241641

Helmstaedter C, Kurthen M, Linke DB, Elger CE (1997)
Patterns of language dominance in focal left and right hemisphere epilepsies: relation to MRI findings, EEG, sex, and age at onset of epilepsy
Brain Cogn, 33 (2), 135-50
DOI 10.1006/brcg.1997.0888, PubMed 9073369

Kurthen M, Helmstaedter C, Elger CE, Linke DB (1997)
Sex differences in cerebral language dominance in complex-partial epilepsy
Naturwissenschaften, 84 (3), 131-3
DOI 10.1007/s001140050363, PubMed 9112241

Lendt M, Helmstaedter C, Elger CE (1997)
Pre- and postoperative socioeconomic development of 151 patients with focal epilepsies
Epilepsia, 38 (12), 1330-7
DOI 10.1111/j.1528-1157.1997.tb00071.x, PubMed 9578529

Müller H, Hasse-Sander I, Horn R, Helmstaedter C, Elger CE (1997)
Rey Auditory-Verbal Learning Test: structure of a modified German version
J Clin Psychol, 53 (7), 663-71
DOI 10.1002/(sici)1097-4679(199711)53:7<663::aid-jclp4>3.0.co;2-j, PubMed 9356896

Publications 1996

Düzel E, Hufnagel A, Helmstaedter C, Elger C (1996)
Verbal working memory components can be selectively influenced by transcranial magnetic stimulation in patients with left temporal lobe epilepsy
Neuropsychologia, 34 (8), 775-83
DOI 10.1016/0028-3932(95)00160-3, PubMed 8817507

Helmstaedter C, Elger CE (1996)
Cognitive consequences of two-thirds anterior temporal lobectomy on verbal memory in 144 patients: a three-month follow-up study
Epilepsia, 37 (2), 171-80
DOI 10.1111/j.1528-1157.1996.tb00009.x, PubMed 8635428

Helmstaedter C, Kemper B, Elger CE (1996)
Neuropsychological aspects of frontal lobe epilepsy
Neuropsychologia, 34 (5), 399-406
DOI 10.1016/0028-3932(95)00121-2, PubMed 9148196

Publications 1995

Helmstaedter C, Pohl C, Elger CE (1995)
Relations between verbal and nonverbal memory performance: evidence of confounding effects particularly in patients with right temporal lobe epilepsy
Cortex, 31 (2), 345-55
DOI 10.1016/s0010-9452(13)80367-x, PubMed 7555011

Publications 1994

Helmstaedter C, Elger CE, Lendt M (1994)
Postictal courses of cognitive deficits in focal epilepsies
Epilepsia, 35 (5), 1073-8
DOI 10.1111/j.1528-1157.1994.tb02557.x, PubMed 7925154

Helmstaedter C, Kurthen M, Linke DB, Elger CE (1994)
Right hemisphere restitution of language and memory functions in right hemisphere language-dominant patients with left temporal lobe epilepsy
Brain, 117 ( Pt 4), 729-37
DOI 10.1093/brain/117.4.729, PubMed 7922460

Kurthen M, Helmstaedter C, Linke DB, Hufnagel A, Elger CE, Schramm J (1994)
Quantitative and qualitative evaluation of patterns of cerebral language dominance. An amobarbital study
Brain Lang, 46 (4), 536-64
DOI 10.1006/brln.1994.1030, PubMed 8044676

Publications 1993

Helmstaedter C, Wagner G, Elger CE (1993)
Differential effects of first antiepileptic drug application on cognition in lesional and non-lesional patients with epilepsy
Seizure, 2 (2), 125-30
DOI 10.1016/s1059-1311(05)80115-3, PubMed 8167962

König M, Hufnagel A, Helmstaedter C, Elger CE (1993)
[A special case of frontal lobe epilepsy]
Nervenarzt, 64 (2), 131-5
PubMed 8450895

Publications 1992

Helmstaedter C, Hartmann A, Niese C, Brackmann HH, Sass R (1992)
[Stage-independence and individual outcome of neuro-cognitive deficits in HIV. A follow-up study of 62 HIV-positive hemophilic patients]
Nervenarzt, 63 (2), 88-94
PubMed 1565174

Helmstaedter C, Hufnagel A, Elger CE (1992)
Seizures during cognitive testing in patients with temporal lobe epilepsy: possibility of seizure induction by cognitive activation
Epilepsia, 33 (5), 892-7
DOI 10.1111/j.1528-1157.1992.tb02197.x, PubMed 1396432

Kurthen M, Helmstaedter C, Linke DB, Solymosi L, Elger CE, Schramm J (1992)
Interhemispheric dissociation of expressive and receptive language functions in patients with complex-partial seizures: an amobarbital study
Brain Lang, 43 (4), 694-712
DOI 10.1016/0093-934x(92)90091-r, PubMed 1483198

Riedel RR, Helmstaedter C, Bülau P, Durwen HF, Brackmann H, Fimmers R, Clarenbach P, Miller EN, Böttcher M (1992)
Early signs of cognitive deficits among human immunodeficiency virus-positive hemophiliacs
Acta Psychiatr Scand, 85 (4), 321-6
DOI 10.1111/j.1600-0447.1992.tb01476.x, PubMed 1595365

Publications 1991

Helmstaedter C, Pohl C, Hufnagel A, Elger CE (1991)
Visual learning deficits in nonresected patients with right temporal lobe epilepsy
Cortex, 27 (4), 547-55
DOI 10.1016/s0010-9452(13)80004-4, PubMed 1782789

Publications 1990

Helmstaedter C, Durwen HF (1990)
[The Verbal Learning and Retention Test. A useful and differentiated tool in evaluating verbal memory performance]
Schweiz Arch Neurol Psychiatr (1985), 141 (1), 21-30
PubMed 1690447

Publications 1989

Durwen HF, Helmstaedter C, Elger CE (1989)
[Neuropsychological and psychosocial aspects of surgical therapy of epilepsy]
Nervenarzt, 60 (1), 10-6
PubMed 2646549

Publications 1988

Helmstaedter C, Riedel R, Stefan H (1988)
[Treatment of drug-resistant focal epilepsy using visual orientation activity]
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb, 19 (2), 92-5
PubMed 3136002

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