Publications 2025

Mekonnen T, Skirbekk V, Håberg AK, Engdahl B, Zotcheva E, Jugessur A, Bowen C, Selbaek G, Kohler HP, Harris JR, Tom SE, Krokstad S, Edwin TH, Kristjansson D, Ellingjord-Dale M, Stern Y, Bratsberg B, Strand BH (2025)
Mediators of educational differences in dementia risk later in life: evidence from the HUNT study
BMC Public Health, 25 (1), 1336
DOI 10.1186/s12889-025-22592-9, PubMed 40211155

Mekonnen T, Skirbekk V, Zotcheva E, Engdahl B, Bratsberg B, Jugessur A, Bowen C, Selbæk G, Kohler HP, Harris JR, Tom SE, Krokstad S, Edwin TH, Wedatilake Y, Wolfova K, Kristjansson D, Stern Y, Håberg AK, Strand BH (2025)
Number of children and dementia risk: a causal mediation analysis using data from the HUNT study linked with national registries in Norway
BMC Neurol, 25 (1), 39
DOI 10.1186/s12883-025-04044-4, PubMed 39871199

Ustad A, Edwin TH, Melsæter KN, Sverdrup K, Tangen GG, Døhl Ø, Thingstad P, Vereijken B, Skjæret-Maroni N (2025)
Daily physical activity and trajectories of care service use among older adults: the HUNT4 Trondheim 70+ study
Front Public Health, 13, 1539179
DOI 10.3389/fpubh.2025.1539179, PubMed 40041185

Publications 2024

Aksnes M, Schibstad MH, Chaudhry FA, Neerland BE, Caplan G, Saltvedt I, Eldholm RS, Myrstad M, Edwin TH, Persson K, Idland AV, Pollmann CT, Olsen RB, Wyller TB, Zetterberg H, Cunningham E, Watne LO (2024)
Differences in metalloproteinases and their tissue inhibitors in the cerebrospinal fluid are associated with delirium
Commun Med (Lond), 4 (1), 124
DOI 10.1038/s43856-024-00558-z, PubMed 38937571

Amland R, Selbæk G, Brækhus A, Edwin TH, Engedal K, Knapskog AB, Olsrud ER, Persson K (2024)
Clinically feasible automated MRI volumetry of the brain as a prognostic marker in subjective and mild cognitive impairment
Front Neurol, 15, 1425502
DOI 10.3389/fneur.2024.1425502, PubMed 39011362

Edwin TH, Håberg AK, Zotcheva E, Bratsberg B, Jugessur A, Engdahl B, Bowen C, Selbæk G, Kohler HP, Harris JR, Tom SE, Krokstad S, Mekonnen T, Stern Y, Skirbekk VF, Strand BH (2024)
Trajectories of Occupational Cognitive Demands and Risk of Mild Cognitive Impairment and Dementia in Later Life: The HUNT4 70+ Study
Neurology, 102 (9), e209353
DOI 10.1212/WNL.0000000000209353, PubMed 38630959

Knapskog AB, Edwin TH, Ueland PM, Ulvik A, Fang EF, Eldholm RS, Halaas NB, Giil LM, Saltvedt I, Watne LO, Aksnes M (2024)
Sex-specific associations of kynurenic acid with neopterin in Alzheimer's disease
Alzheimers Res Ther, 16 (1), 167
DOI 10.1186/s13195-024-01531-7, PubMed 39068471

Persson K, Barca ML, Edwin TH, Cavallin-Eklund L, Tangen GG, Rhodius-Meester HFM, Selbæk G, Knapskog AB, Engedal K (2024)
Regional MRI volumetry using NeuroQuant versus visual rating scales in patients with cognitive impairment and dementia
Brain Behav, 14 (2), e3397
DOI 10.1002/brb3.3397, PubMed 38600026

Publications 2023

Aksnes M, Edwin TH, Saltvedt I, Eldholm RS, Chaudhry FA, Halaas NB, Myrstad M, Watne LO, Knapskog AB (2023)
Sex-specific associations of matrix metalloproteinases in Alzheimer's disease
Biol Sex Differ, 14 (1), 35
DOI 10.1186/s13293-023-00514-x, PubMed 37221606

Knapskog AB, Aksnes M, Edwin TH, Ueland PM, Ulvik A, Fang EF, Eldholm RS, Halaas NB, Saltvedt I, Giil LM, Watne LO (2023)
Higher concentrations of kynurenic acid in CSF are associated with the slower clinical progression of Alzheimer's disease
Alzheimers Dement, 19 (12), 5573-5582
DOI 10.1002/alz.13162, PubMed 37264981

Persson K, Leonardsen EH, Edwin TH, Knapskog AB, Tangen GG, Selbæk G, Wolfers T, Westlye LT, Engedal K (2023)
Diagnostic accuracy of brain age prediction in a memory clinic population and comparison with clinically available volumetric measures
Sci Rep, 13 (1), 14957
DOI 10.1038/s41598-023-42354-0, PubMed 37696909

Zotcheva E, Bratsberg B, Strand BH, Jugessur A, Engdahl BL, Bowen C, Selbæk G, Kohler HP, Harris JR, Weiss J, Tom SE, Krokstad S, Mekonnen T, Edwin TH, Stern Y, Håberg AK, Skirbekk V (2023)
Trajectories of occupational physical activity and risk of later-life mild cognitive impairment and dementia: the HUNT4 70+ study
Lancet Reg Health Eur, 34, 100721
DOI 10.1016/j.lanepe.2023.100721, PubMed 37927437

Publications 2022

Müller EG, Edwin TH, Strand BH, Stokke C, Revheim ME, Knapskog AB (2022)
Is Amyloid Burden Measured by 18F-Flutemetamol PET Associated with Progression in Clinical Alzheimer's Disease?
J Alzheimers Dis, 85 (1), 197-205
DOI 10.3233/JAD-215046, PubMed 34776444

Müller EG, Stokke C, Stokmo HL, Edwin TH, Knapskog AB, Revheim ME (2022)
Evaluation of semi-quantitative measures of ¹⁸F-flutemetamol PET for the clinical diagnosis of Alzheimer's disease
Quant Imaging Med Surg, 12 (1), 493-509
DOI 10.21037/qims-21-188, PubMed 34993096

Persson K, Edwin TH, Knapskog AB, Tangen GG, Selbæk G, Engedal K (2022)
Hippocampal Atrophy Subtypes of Alzheimer's Disease Using Automatic MRI in a Memory Clinic Cohort: Clinical Implications
Dement Geriatr Cogn Disord, 51 (1), 80-89
DOI 10.1159/000522382, PubMed 35344967

Publications 2021

Aksnes M, Tiiman A, Edwin TH, Terenius L, Bogdanović N, Vukojević V, Knapskog AB (2021)
Comparison of Cerebrospinal Fluid Amyloidogenic Nanoplaques With Core Biomarkers of Alzheimer's Disease
Front Aging Neurosci, 12, 608628
DOI 10.3389/fnagi.2020.608628, PubMed 33488383

Aksnes M, Aass HCD, Tiiman A, Edwin TH, Terenius L, Bogdanović N, Vukojević V, Knapskog AB (2021)
Associations of cerebrospinal fluid amyloidogenic nanoplaques with cytokines in Alzheimer's disease
Transl Neurodegener, 10 (1), 18
DOI 10.1186/s40035-021-00244-3, PubMed 34099032

Edwin TH, Strand BH, Persson K, Engedal K, Selbaek G, Knapskog AB (2021)
Neuropsychiatric symptoms and comorbidity: Associations with dementia progression rate in a memory clinic cohort
Int J Geriatr Psychiatry, 36 (6), 960-969
DOI 10.1002/gps.5500, PubMed 33462872

Publications 2020

Aksnes M, Müller EG, Tiiman A, Edwin TH, Terenius L, Revheim ME, Vukojević V, Bogdanović N, Knapskog AB (2020)
Amyloidogenic Nanoplaques in Cerebrospinal Fluid: Relationship to Amyloid Brain Uptake and Clinical Alzheimer's Disease in a Memory Clinic Cohort
J Alzheimers Dis, 77 (2), 831-842
DOI 10.3233/JAD-200237, PubMed 32741818

Edwin TH, Henjum K, Nilsson LNG, Watne LO, Persson K, Eldholm RS, Saltvedt I, Halaas NB, Selbæk G, Engedal K, Strand BH, Knapskog AB (2020)
A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease
Alzheimers Dement (Amst), 12 (1), e12128
DOI 10.1002/dad2.12128, PubMed 33313376

Edwin TH, Strand BH, Persson K, Engedal K, Selbæk G, Knapskog AB (2020)
Trajectories and risk factors of dementia progression: a memory clinic cohort followed up to 3 years from diagnosis
Int Psychogeriatr, 33 (8), 779-789
DOI 10.1017/S1041610220003270, PubMed 33213607

Mjørud M, Selbæk G, Bjertness E, Edwin TH, Engedal K, Knapskog AB, Strand BH (2020)
Time from dementia diagnosis to nursing-home admission and death among persons with dementia: A multistate survival analysis
PLoS One, 15 (12), e0243513
DOI 10.1371/journal.pone.0243513, PubMed 33275638

Publications 2019

Müller EG, Edwin TH, Stokke C, Navelsaker SS, Babovic A, Bogdanovic N, Knapskog AB, Revheim ME (2019)
Amyloid-β PET-Correlation with cerebrospinal fluid biomarkers and prediction of Alzheimer´s disease diagnosis in a memory clinic
PLoS One, 14 (8), e0221365
DOI 10.1371/journal.pone.0221365, PubMed 31430334

Publications 2018

Strand BH, Knapskog AB, Persson K, Edwin TH, Amland R, Mjørud M, Bjertness E, Engedal K, Selbæk G (2018)
Survival and years of life lost in various aetiologies of dementia, mild cognitive impairment (MCI) and subjective cognitive decline (SCD) in Norway
PLoS One, 13 (9), e0204436
DOI 10.1371/journal.pone.0204436, PubMed 30240425