Specific projects focus on the epigenetic reprogramming of early embryo development and its significance for human reproduction. An overarching theme is the understanding of mechanisms and epigenetic information in the passing of life from one generation to the next. Aging related projects have a focus on stem cell aging and rejuvenation after hematopoietic stem cell transplantation. We have a particular interest in the mechanisms of aging and rejuvenation. In addition, the Dahl lab works on Neuroepigenetics and Cancer epimutations.