Publications 2024

Chandrasekaran TT, Choudalakis M, Bröhm A, Weirich S, Kouroukli AG, Ammerpohl O, Rathert P, Bashtrykov P, Jeltsch A (2024)
SETDB1 activity is globally directed by H3K14 acetylation via its Triple Tudor Domain
Nucleic Acids Res (in press)
DOI 10.1093/nar/gkae1053, PubMed 39540436

Choudalakis M, Bashtrykov P, Jeltsch A (2024)
RepEnTools: an automated repeat enrichment analysis package for ChIP-seq data reveals hUHRF1 Tandem-Tudor domain enrichment in young repeats
Mob DNA, 15 (1), 6
DOI 10.1186/s13100-024-00315-y, PubMed 38570859

Publications 2023

Choudalakis M, Kungulovski G, Mauser R, Bashtrykov P, Jeltsch A (2023)
Refined read-out: The hUHRF1 Tandem-Tudor domain prefers binding to histone H3 tails containing K4me1 in the context of H3K9me2/3
Protein Sci, 32 (9), e4760
DOI 10.1002/pro.4760, PubMed 37593997

Kunert S, Linhard V, Weirich S, Choudalakis M, Osswald F, Krämer L, Köhler AR, Bröhm A, Wollenhaupt J, Schwalbe H, Jeltsch A (2023)
The MECP2-TRD domain interacts with the DNMT3A-ADD domain at the H3-tail binding site
Protein Sci, 32 (1), e4542
DOI 10.1002/pro.4542, PubMed 36519786

Publications 2022

Schnee P, Choudalakis M, Weirich S, Khella MS, Carvalho H, Pleiss J, Jeltsch A (2022)
Mechanistic basis of the increased methylation activity of the SETD2 protein lysine methyltransferase towards a designed super-substrate peptide
Commun Chem, 5 (1), 139
DOI 10.1038/s42004-022-00753-w, PubMed 36697904

Publications 2021

Pinter S, Knodel F, Choudalakis M, Schnee P, Kroll C, Fuchs M, Broehm A, Weirich S, Roth M, Eisler SA, Zuber J, Jeltsch A, Rathert P (2021)
A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation
Nucleic Acids Res, 49 (8), 4350-4370
DOI 10.1093/nar/gkab180, PubMed 33823549

Publications 2019

Dukatz M, Holzer K, Choudalakis M, Emperle M, Lungu C, Bashtrykov P, Jeltsch A (2019)
H3K36me2/3 Binding and DNA Binding of the DNA Methyltransferase DNMT3A PWWP Domain Both Contribute to its Chromatin Interaction
J Mol Biol, 431 (24), 5063-5074
DOI 10.1016/j.jmb.2019.09.006, PubMed 31634469