Therapeutic nuclear medicine: Theranostic radiopharmaceuticals for metastatic cancer -focusing on targeted alpha therapy (Co-lead, South-Eastern Norway Regional Health Authority Grant), SIMPLERAD (Co-lead WP4, funded by the European Union), Biodistribution and dosimetry in a phase 1 trial of 224-Ra-CaCO3 particles (funded by sponsor), Dose-effects for a novel 177-Lu based treatment of non-Hodgkin lymphoma (South-Eastern Norway Regional Health Authority Research Grant), Simulation tools and quantitative 90-Y PET/CT for Selective Internal Radiation Therapy (South-Eastern Norway Regional Health Authority Innovation Grant), Dosimetry-based treatment planning of 131-I therapy.
Other studies: Quantitative PET parameters as predictors for patient outcome (part of different lymphoma trials), radiomics investigations, novel PET tracers for multiple myeloma assessments, and various technical projects related to image reconstruction and analyses.
Blakkisrud J, Peterson AB, Wildermann SJ, Kingkiner G, Wong KK, Wang C, Frey KA, Stokke C, Dewaraja YK(2024) SPECT/CT Image-Derived Absorbed Dose to Red Marrow Correlates with Hematologic Toxicity in Patients Treated with [177Lu]Lu-DOTATATE J Nucl Med(in press) DOI 10.2967/jnumed.123.266843, PubMed 38548350
Stokke C, Gnesin S, Tran-Gia J, Cicone F, Holm S, Cremonesi M, Blakkisrud J, Wendler T, Gillings N, Herrmann K, Mottaghy FM, Gear J(2024) EANM guidance document: dosimetry for first-in-human studies and early phase clinical trials Eur J Nucl Med Mol Imaging, 51(5), 1268-1286 DOI 10.1007/s00259-024-06640-x, PubMed 38366197
Peters S, Tran-Gia J, Agius S, Ivashchenko OV, Badel JN, Cremonesi M, Kurth J, Gabiña PM, Richetta E, Gleisner KS, Tipping J, Bardiès M, Stokke C(2023) Implementation of dosimetry for molecular radiotherapy; results from a European survey Phys Med, 117, 103196 DOI 10.1016/j.ejmp.2023.103196, PubMed 38104033
Get in touch
Contact information Group Leader Caroline Stokke, PhD, Assoc. Prof., Department of Physics and Computational Radiology, carsto@ous-hf.no, (0047) 98685214