Publications 2024

Antonelli G, Libanio D, De Groof AJ, van der Sommen F, Mascagni P, Sinonquel P, Abdelrahim M, Ahmad O, Berzin T, Bhandari P, Bretthauer M, Coimbra M, Dekker E, Ebigbo A, Eelbode T, Frazzoni L, Gross SA, Ishihara R, Kaminski MF, Messmann H, Mori Y, Padoy N, Parasa S, Pilonis ND, Renna F et al. (2024)
QUAIDE - Quality assessment of AI preclinical studies in diagnostic endoscopy
Gut (in press)
DOI 10.1136/gutjnl-2024-332820, PubMed 39406471

Anvari S, Dadgar K, Galts C, Bretthauer M (2024)
Gastroenterology/Hepatology: What You May Have Missed in 2023
Ann Intern Med, 177 (5_Supplement), S27-S36
DOI 10.7326/M24-0505, PubMed 38621241

Baile-Maxía S, Mangas-Sanjuán C, Ladabaum U, Sánchez-Ardila C, Sala-Miquel N, Hassan C, Rutter MD, Bretthauer M, Zapater P, Jover R (2024)
Risk factors for metachronous colorectal cancer or advanced lesions after endoscopic resection of serrated polyps: a systematic review and meta-analysis
Gastrointest Endosc, 100 (4), 605-615.e14
DOI 10.1016/j.gie.2024.05.021, PubMed 38851458

Bretthauer M (2024)
How to learn from interval cancers in colorectal cancer screening
Endoscopy, 56 (5), 373-375
DOI 10.1055/a-2279-9932, PubMed 38479414

Bretthauer M, Kaminski MF, Kalager M (2024)
Lifetime Gained With Cancer Screening-Reply
JAMA Intern Med, 184 (2), 228
DOI 10.1001/jamainternmed.2023.7067, PubMed 38165695

Bretthauer M, Pilonis ND (2024)
Brief sigmoidoscopy provides 21-year colorectal cancer risk reduction in men
Lancet Gastroenterol Hepatol, 9 (9), 777-779
DOI 10.1016/S2468-1253(24)00199-7, PubMed 39038481

Bretthauer M, Ponchon T (2024)
ESGE and Public Advocacy
Endoscopy, 56 (6), 457-458
DOI 10.1055/a-2277-2204, PubMed 38810622

Burra P, Amil Dias J, Torres J, Botos A, Acedo P, Bertelsen B, Bretthauer M, Carboni A, Dugic A, Fracasso P, Koltai T, Leone S, Maravic Z, Matysiak-Budnik T, McColaugh L, Mishkovikj M, Wickramasinghe K, van Leerdam M (2024)
Advancing patient-centered care: Recent developments in UEG's patient relations
United European Gastroenterol J, 12 (6), 816-818
DOI 10.1002/ueg2.12607, PubMed 38867386

Helsingen LM, Langeland EA, Pisani SER, Vandvik PO, Haavardsholm EA, Malt UF, Müller C, Stensvold A, Kalager M, Bretthauer M (2024)
[Scraps of national clinical guidelines from the Directorate of Health]
Tidsskr Nor Laegeforen, 144 (5)
DOI 10.4045/tidsskr.24.0141, PubMed 38651715

Juul FE, Cross AJ, Schoen RE, Senore C, Pinsky PF, Miller EA, Segnan N, Wooldrage K, Wieszczy-Szczepanik P, Armaroli P, Garborg KK, Adami HO, Hoff G, Kalager M, Bretthauer M, Holme Ø, Løberg M (2024)
Effectiveness of Colonoscopy Screening vs Sigmoidoscopy Screening in Colorectal Cancer
JAMA Netw Open, 7 (2), e240007
DOI 10.1001/jamanetworkopen.2024.0007, PubMed 38421651

Martínez-Roca A, Cubiella J, García-Heredia A, Guill-Berbegal D, Baile-Maxía S, Mangas-Sanjuán C, Sala-Miquel N, Madero-Velazquez L, Alenda C, Zapater P, González-Núñez C, Iglesias-Gómez A, Codesido-Prado L, Díez-Martín A, Kaminski MF, Erichsen R, Adami HO, Ferlitsch M, Pellisé M, Holme Ø, Dekker E, Bretthauer M, Jover R, EPoS Study Group (2024)
Prediction of metachronous advanced colorectal neoplasia by KRAS mutation in polyps
United European Gastroenterol J (in press)
DOI 10.1002/ueg2.12667, PubMed 39400528

Nilsen JA, Bernklev L, Bretthauer M, Kalager M, Jodal HC, Løberg M, Holme Ø, Juul FE, Frigstad SO (2024)
Surgical treatment of benign colorectal polyps 2008-21
Tidsskr Nor Laegeforen, 144 (10)
DOI 10.4045/tidsskr.23.0722, PubMed 39254026

Nordberg LB, Pohl H, Haavardsholm EA, Lillegraven S, Bretthauer M (2024)
Carbon-Footprint Analyses in RCTs - Toward Sustainable Clinical Practice
N Engl J Med, 390 (24), 2234-2236
DOI 10.1056/NEJMp2402018, PubMed 38749030

Randel KR, Botteri E, de Lange T, Schult AL, Eskeland SL, El-Safadi B, Norvard ER, Bolstad N, Bretthauer M, Hoff G, Holme Ø (2024)
Performance of Faecal Immunochemical Testing for Colorectal Cancer Screening at Varying Positivity Thresholds
Aliment Pharmacol Ther (in press)
DOI 10.1111/apt.18314, PubMed 39373173

Randel KR, Schult AL, Botteri E, Nawaz M, Nguyen DH, Holme Ø, Bretthauer M, Hoff G, de Lange T (2024)
Impact of inadequate bowel cleansing in sigmoidoscopy screening
Scand J Gastroenterol, 59 (8), 1002-1009
DOI 10.1080/00365521.2024.2364213, PubMed 38850200

Rognstad ØB, Botteri E, Hoff G, Bretthauer M, Gulichsen E, Frigstad SO, Holme Ø, Randel KR (2024)
Adverse events after colonoscopy in a randomised colorectal cancer screening trial
BMJ Open Gastroenterol, 11 (1)
DOI 10.1136/bmjgast-2024-001471, PubMed 39375173

Song M, Bretthauer M (2024)
Authors' Reply: Interpreting epidemiologic studies of colonoscopy screening for colorectal cancer prevention
Eur J Epidemiol, 39 (4), 431
DOI 10.1007/s10654-023-01077-2, PubMed 38261147

Xu H, Bretthauer M, Fang F, Ye W, Yin L, Adami HO (2024)
Dramatic improvements in outcome following pancreatoduodenectomy for pancreatic and periampullary cancers
Br J Cancer, 131 (4), 747-754
DOI 10.1038/s41416-024-02757-w, PubMed 38937622

Publications 2023

Adami HO, Kalager M, Bretthauer M (2023)
The Future of Cancer Screening-Guided Without Conflicts of Interest
JAMA Intern Med, 183 (10), 1047-1048
DOI 10.1001/jamainternmed.2023.4064, PubMed 37639267

Bretthauer M, Gerke S, Hassan C, Ahmad OF, Mori Y (2023)
The New European Medical Device Regulation: Balancing Innovation and Patient Safety
Ann Intern Med, 176 (6), 844-848
DOI 10.7326/M23-0454, PubMed 37068279

Bretthauer M, Kalager M (2023)
What is my risk, doctor? How to convey disease risk and treatment effects
BMJ, 381, e075289
DOI 10.1136/bmj-2022-075289, PubMed 37328165

Bretthauer M, Løberg M, Kaminski MF (2023)
Colonoscopy Screening and Colorectal Cancer Incidence and Mortality. Reply
N Engl J Med, 388 (4), 378-379
DOI 10.1056/NEJMc2215192, PubMed 36720146

Bretthauer M, Mori Y, Zessner-Spitzenberg J, Kaminski MF, Siersema PD, Ponchon T, Messmann H, Gralnek IM, Bisschops R, Hassan C (2023)
Gastrointestinal endoscopy devices and the European Union Medical Device Regulation: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement
Endoscopy, 55 (6), 578-581
DOI 10.1055/a-2052-2540, PubMed 37080238

Bretthauer M, Wieszczy P, Løberg M, Kaminski MF, Werner TF, Helsingen LM, Mori Y, Holme Ø, Adami HO, Kalager M (2023)
Estimated Lifetime Gained With Cancer Screening Tests: A Meta-Analysis of Randomized Clinical Trials
JAMA Intern Med, 183 (11), 1196-1203
DOI 10.1001/jamainternmed.2023.3798, PubMed 37639247

Bretthauer M, Yang YX (2023)
New American College of Physicians Guidance on Colorectal Cancer Screening: Less Is More
Ann Intern Med, 176 (8), 1127-1128
DOI 10.7326/M23-1695, PubMed 37523706

Everett SM, Triantafyllou K, Hassan C, Mergener K, Tham TC, Almeida N, Antonelli G, Axon A, Bisschops R, Bretthauer M, Costil V, Foroutan F, Gauci J, Hritz I, Messmann H, Pellisé M, Roelandt P, Seicean A, Tziatzios G, Voiosu A, Gralnek IM (2023)
Informed consent for endoscopic procedures: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement
Endoscopy, 55 (10), 952-966
DOI 10.1055/a-2133-3365, PubMed 37557899

Jodal HC, Bretthauer M, Løberg M (2023)
[Colorectal cancer screening also for younger adults?]
Tidsskr Nor Laegeforen, 143 (18)
DOI 10.4045/tidsskr.23.0553, PubMed 38088289

Jodal HC, Wieszczy-Szczepanik P, Klotz D, Herfindal M, Barua I, Tag P, Helsingen LM, Refsum E, Holme Ø, Adami HO, Bretthauer M, Kalager M, Løberg M (2023)
A Comparison of Risk Classification Systems of Colorectal Adenomas: A Case-Cohort Study
Gastroenterology, 165 (2), 483-491.e7
DOI 10.1053/j.gastro.2023.04.028, PubMed 37146913

Langeland EA, Pisani SER, Kalager M, Bretthauer M, Helsingen LM (2023)
[Do the Directorate of Health’s guidelines adhere to international standards for trustworthy clinical practice?]
Tidsskr Nor Laegeforen, 143 (14)
DOI 10.4045/tidsskr.23.0110, PubMed 37830968

Song M, Bretthauer M (2023)
Interpreting epidemiologic studies of colonoscopy screening for colorectal cancer prevention: understanding the mechanisms of action is key
Eur J Epidemiol, 38 (9), 929-931
DOI 10.1007/s10654-023-01043-y, PubMed 37667139

Song M, Bretthauer M (2023)
Authors' Reply: Interpreting epidemiologic studies of colorectal cancer prevention
Eur J Epidemiol, 39 (1), 99
DOI 10.1007/s10654-023-01070-9, PubMed 37950085

Spadaccini M, Hassan C, Rondonotti E, Antonelli G, Andrisani G, Lollo G, Auriemma F, Iacopini F, Facciorusso A, Maselli R, Fugazza A, Bambina Bergna IM, Cereatti F, Mangiavillano B, Radaelli F, Di Matteo F, Gross SA, Sharma P, Mori Y, Bretthauer M, Rex DK, Repici A, CERTAIN Study Group (2023)
Combination of Mucosa-Exposure Device and Computer-Aided Detection for Adenoma Detection During Colonoscopy: A Randomized Trial
Gastroenterology, 165 (1), 244-251.e3
DOI 10.1053/j.gastro.2023.03.237, PubMed 37061169

Tønnesen CJ, Hjelmesæth J, Aabakken L, Lund RS, Johnson LK, Hertel JK, Kalager M, Løberg M, Bretthauer M (2023)
A pilot study of implementation of endoscopic sleeve gastroplasty (ESG) in Norway
Scand J Gastroenterol, 58 (10), 1180-1184
DOI 10.1080/00365521.2023.2204389, PubMed 37128713

Yu J, Refsum E, Wieszczy P, Helsingen LM, Perrin V, Högdén A, Løberg M, Blom J, Bretthauer M, Adami HO, Ye W, Kalager M (2023)
Risk of malignant lymphomas in patients with inflammatory bowel disease: a population-based cohort study
BMJ Open Gastroenterol, 10 (1)
DOI 10.1136/bmjgast-2022-001037, PubMed 37142293

Zeng L, Helsingen LM, Bretthauer M, Agoritsas T, Vandvik PO, Mustafa RA, Busse J, Siemieniuk RAC, Lytvyn L, Li SA, Yang M, Yan L, Zhang L, Brignardello-Petersen R, Guyatt GH (2023)
A novel framework for incorporating patient values and preferences in making guideline recommendations: guideline panel surveys
J Clin Epidemiol, 161, 164-172
DOI 10.1016/j.jclinepi.2023.07.003, PubMed 37453455

Zeng L, Li SA, Yang M, Yan L, Helsingen LM, Bretthauer M, Agoritsas T, Vandvik PO, Mustafa RA, Busse J, Siemieniuk RAC, Lytvyn L, Zhang L, Brignardello-Petersen R, Guyatt GH (2023)
Qualitative study of guideline panelists: innovative surveys provided valuable insights regarding patient values and preferences
J Clin Epidemiol, 161, 173-180
DOI 10.1016/j.jclinepi.2023.07.014, PubMed 37517505

Publications 2022

Ainechi D, Misawa M, Barua I, Larsen SLV, Paulsen V, Garborg KK, Aabakken L, Tønnesen CJ, Løberg M, Kalager M, Kudo SE, Hotta K, Ohtsuka K, Saito S, Ikematsu H, Saito Y, Matsuda T, Itoh H, Mori K, Bretthauer M, Mori Y (2022)
Impact of artificial intelligence on colorectal polyp detection for early-career endoscopists: an international comparative study
Scand J Gastroenterol, 57 (10), 1272-1277
DOI 10.1080/00365521.2022.2070436, PubMed 35605150

Areia M, Mori Y, Correale L, Repici A, Bretthauer M, Sharma P, Taveira F, Spadaccini M, Antonelli G, Ebigbo A, Kudo SE, Arribas J, Barua I, Kaminski MF, Messmann H, Rex DK, Dinis-Ribeiro M, Hassan C (2022)
Cost-effectiveness of artificial intelligence for screening colonoscopy: a modelling study
Lancet Digit Health, 4 (6), e436-e444
DOI 10.1016/S2589-7500(22)00042-5, PubMed 35430151

Baile-Maxía S, Mangas-Sanjuán C, Ladabaum U, Hassan C, Rutter MD, Bretthauer M, Medina-Prado L, Sala-Miquel N, Pomares OM, Zapater P, Jover R (2022)
Risk Factors for Metachronous Colorectal Cancer or Advanced Adenomas After Endoscopic Resection of High-risk Adenomas
Clin Gastroenterol Hepatol, 21 (3), 630-643
DOI 10.1016/j.cgh.2022.12.005, PubMed 36549471

Barua I, Misawa M, Glissen Brown JR, Walradt T, Kudo SE, Sheth SG, Nee J, Iturrino J, Mukherjee R, Cheney CP, Sawhney MS, Pleskow DK, Mori K, Løberg M, Kalager M, Wieszczy P, Bretthauer M, Berzin TM, Mori Y (2022)
Speedometer for withdrawal time monitoring during colonoscopy: a clinical implementation trial
Scand J Gastroenterol, 58 (6), 664-670
DOI 10.1080/00365521.2022.2154616, PubMed 36519564

Barua I, Wieszczy P, Kudo SE, Misawa M, Holme Ø, Gulati S, Williams S, Mori K, Itoh H, Takishima K, Mochizuki K, Miyata Y, Mochida K, Akimoto Y, Kuroki T, Morita Y, Shiina O, Kato S, Nemoto T, Hayee B, Patel M, Gunasingam N, Kent A, Emmanuel A, Munck C et al. (2022)
Real-Time Artificial Intelligence-Based Optical Diagnosis of Neoplastic Polyps during Colonoscopy
NEJM Evid, 1 (6), EVIDoa2200003
DOI 10.1056/EVIDoa2200003, PubMed 38319238

Bretthauer M, Løberg M, Wieszczy P, Kalager M, Emilsson L, Garborg K, Rupinski M, Dekker E, Spaander M, Bugajski M, Holme Ø, Zauber AG, Pilonis ND, Mroz A, Kuipers EJ, Shi J, Hernán MA, Adami HO, Regula J, Hoff G, Kaminski MF, NordICC Study Group (2022)
Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death
N Engl J Med, 387 (17), 1547-1556
DOI 10.1056/NEJMoa2208375, PubMed 36214590

Burra P, Arvanitakis M, Dias JA, Bretthauer M, Dugic A, Hartmann D, Michl P, Seufferlein T, Torres J, Törnblom H, van Leerdam ME, Zelber-Sagi S, Botos A (2022)
UEG position paper: Obesity and digestive health
United European Gastroenterol J, 10 (10), 1199-1201
DOI 10.1002/ueg2.12334, PubMed 36457185

Burra P, Bretthauer M, Buti Ferret M, Dugic A, Fracasso P, Leja M, Matysiak Budnik T, Michl P, Ricciardiello L, Seufferlein T, van Leerdam M, Botos A (2022)
Digestive cancer screening across Europe
United European Gastroenterol J, 10 (4), 435-437
DOI 10.1002/ueg2.12230, PubMed 35474447

Hassan C, Piovani D, Spadaccini M, Parigi T, Khalaf K, Facciorusso A, Fugazza A, Rösch T, Bretthauer M, Mori Y, Sharma P, Rex DK, Bonovas S, Repici A (2022)
Variability in adenoma detection rate in control groups of randomized colonoscopy trials: a systematic review and meta-analysis
Gastrointest Endosc, 97 (2), 212-225.e7
DOI 10.1016/j.gie.2022.10.009, PubMed 36243103

Hassan C, Sharma P, Mori Y, Bretthauer M, Rex DK, Combo Study Group, Repici A (2022)
Comparative Performance of Artificial Intelligence Optical Diagnosis Systems for Leaving in Situ Colorectal Polyps
Gastroenterology, 164 (3), 467-469.e4
DOI 10.1053/j.gastro.2022.10.021, PubMed 36328079

Helsingen LM, Løberg M, Bretthauer M, Kalager M (2022)
Reply to: Letter to the Editor regarding "Covid-19 transmission in fitness centers in Norway-a randomized trial"
BMC Public Health, 22 (1), 2437
DOI 10.1186/s12889-022-14799-x, PubMed 36575428

Ichimasa K, Nakahara K, Kudo SE, Misawa M, Bretthauer M, Shimada S, Takehara Y, Mukai S, Kouyama Y, Miyachi H, Sawada N, Mori K, Ishida F, Mori Y (2022)
Novel "resect and analysis" approach for T2 colorectal cancer with use of artificial intelligence
Gastrointest Endosc, 96 (4), 665-672.e1
DOI 10.1016/j.gie.2022.04.1305, PubMed 35500659

Jodal HC, Bretthauer M, Kalager M, Løberg M (2022)
Letter: long-term colorectal cancer incidence and mortality after adenoma removal associated with heritable factors, colonoscopic surveillance and aspirin-authors' reply
Aliment Pharmacol Ther, 55 (10), 1363-1364
DOI 10.1111/apt.16929, PubMed 35472187

Jodal HC, Juul FE, Barua I, Bretthauer M, Kalager M, Løberg M, Emilsson L (2022)
Emergency hospital admissions, prognosis, and population mortality in Norway during the first wave of the Covid-19 epidemic
Scand J Public Health, 50 (6), 795-802
DOI 10.1177/14034948221082959, PubMed 35546560

Juul FE, Cross AJ, Schoen RE, Senore C, Pinsky P, Miller E, Segnan N, Wooldrage K, Wieszczy-Szczepanik P, Armaroli P, Garborg KK, Adami HO, Hoff G, Kalager M, Bretthauer M, Løberg M, Holme Ø (2022)
15-Year Benefits of Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality : A Pooled Analysis of Randomized Trials
Ann Intern Med, 175 (11), 1525-1533
DOI 10.7326/M22-0835, PubMed 36215714

Juul FE, Garborg K, Nesbakken E, Løberg M, Wieszczy P, Cubiella J, Kalager M, Kaminski MF, Erichsen R, Adami HO, Ferlitsch M, Furholm SKB, Zauber AG, Quintero E, Bugajski M, Holme Ø, Dekker E, Jover R, Bretthauer M (2022)
Rates of repeated colonoscopies to clean the colon from low-risk and high-risk adenomas: results from the EPoS trials
Gut, 72 (5), 951-957
DOI 10.1136/gutjnl-2022-327696, PubMed 36307178

Koleth G, Emmanue J, Spadaccini M, Mascagni P, Khalaf K, Mori Y, Antonelli G, Maselli R, Carrara S, Galtieri PA, Pellegatta G, Fugazza A, Anderloni A, Selvaggio C, Bretthauer M, Aghemo A, Spinelli A, Savevski V, Sharma P, Hassan C, Repici A (2022)
Artificial intelligence in gastroenterology: Where are we heading?
Endosc Int Open, 10 (11), E1474-E1480
DOI 10.1055/a-1907-6569, PubMed 36397868

Mori Y, Kaminski MF, Hassan C, Bretthauer M (2022)
Clinical trial designs for artificial intelligence in gastrointestinal endoscopy
Lancet Gastroenterol Hepatol, 7 (9), 785-786
DOI 10.1016/S2468-1253(22)00232-1, PubMed 35932767

Mori Y, Misawa M, Bernal J, Bretthauer M, Kudo SE, Rastogi A, Fernández-Esparrach G (2022)
Artificial intelligence for disease diagnosis: the criterion standard challenge
Gastrointest Endosc, 96 (2), 370-372
DOI 10.1016/j.gie.2022.04.057, PubMed 35489396

Mori Y, Wang P, Løberg M, Misawa M, Repici A, Spadaccini M, Correale L, Antonelli G, Yu H, Gong D, Ishiyama M, Kudo SE, Kamba S, Sumiyama K, Saito Y, Nishino H, Liu P, Glissen Brown JR, Mansour NM, Gross SA, Kalager M, Bretthauer M, Rex DK, Sharma P, Berzin TM et al. (2022)
Impact of Artificial Intelligence on Colonoscopy Surveillance After Polyp Removal: A Pooled Analysis of Randomized Trials
Clin Gastroenterol Hepatol, 21 (4), 949-959.e2
DOI 10.1016/j.cgh.2022.08.022, PubMed 36038128

Pedersen IB, Rawa-Golebiewska A, Calderwood AH, Brix LD, Grode LB, Botteri E, Bugajski M, Kaminski MF, Januszewicz W, Ødegaard H, Kleist B, Kalager M, Løberg M, Bretthauer M, Hoff G, Medhus A, Holme Ø (2022)
Complete polyp resection with cold snare versus hot snare polypectomy for polyps of 4-9 mm: a randomized controlled trial
Endoscopy, 54 (10), 961-969
DOI 10.1055/a-1734-7952, PubMed 35008112

Rodríguez de Santiago E, Dinis-Ribeiro M, Pohl H, Agrawal D, Arvanitakis M, Baddeley R, Bak E, Bhandari P, Bretthauer M, Burga P, Donnelly L, Eickhoff A, Hayee B, Kaminski MF, Karlović K, Lorenzo-Zúñiga V, Pellisé M, Pioche M, Siau K, Siersema PD, Stableforth W, Tham TC, Triantafyllou K, Tringali A, Veitch A et al. (2022)
Reducing the environmental footprint of gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastroenterology and Endoscopy Nurses and Associates (ESGENA) Position Statement
Endoscopy, 54 (8), 797-826
DOI 10.1055/a-1859-3726, PubMed 35803275

Yu J, Refsum E, Helsingen LM, Folseraas T, Ploner A, Wieszczy P, Barua I, Jodal HC, Melum E, Løberg M, Blom J, Bretthauer M, Adami HO, Kalager M, Ye W (2022)
Risk of hepato-pancreato-biliary cancer is increased by primary sclerosing cholangitis in patients with inflammatory bowel disease: A population-based cohort study
United European Gastroenterol J, 10 (2), 212-224
DOI 10.1002/ueg2.12204, PubMed 35107865

Yu J, Refsum E, Perrin V, Helsingen LM, Wieszczy P, Løberg M, Bretthauer M, Adami HO, Ye W, Blom J, Kalager M (2022)
Inflammatory bowel disease and risk of adenocarcinoma and neuroendocrine tumors in the small bowel
Ann Oncol, 33 (6), 649-656
DOI 10.1016/j.annonc.2022.02.226, PubMed 35276334

Publications 2021

Bretthauer M, Helsingen LM, Løberg M, Kalager M, Guyatt G (2021)
Evidence and Precaution for Legal Health Interventions: Learning From the COVID-19 Pandemic
Ann Intern Med, 174 (10), 1456-1457
DOI 10.7326/M21-2839, PubMed 34370512

Bretthauer M, Løberg M, Holme Ø, Adami HO, Kalager M (2021)
Deep learning and cancer biomarkers: recognising lead-time bias
Lancet, 397 (10270), 194
DOI 10.1016/S0140-6736(20)32402-8, PubMed 33453776

Bretthauer M, Schoen RE, Cross AJ, Pinsky PF (2021)
Colorectal Cancer Screening: Randomized Trials Are Essential to Support Recommendations
Ann Intern Med, 175 (1), 129-130
DOI 10.7326/M21-3770, PubMed 34748373

Gralnek IM, Hassan C, Ebigbo A, Fuchs A, Beilenhoff U, Antonelli G, Bisschops R, Arvanitakis M, Bhandari P, Bretthauer M, Kaminski MF, Lorenzo-Zuniga V, Rodriguez de Santiago E, Siersema PD, Tham TC, Triantafyllou K, Tringali A, Voiosu A, Webster G, de Pater M, Fehrke B, Gazic M, Gjergek T, Maasen S, Waagenes W et al. (2021)
ESGE and ESGENA Position Statement on gastrointestinal endoscopy and COVID-19: Updated guidance for the era of vaccines and viral variants
Endoscopy, 54 (2), 211-216
DOI 10.1055/a-1700-4897, PubMed 34933373

Helsingen LM, Løberg M, Refsum E, Gjøstein DK, Wieszczy P, Olsvik Ø, Juul FE, Barua I, Jodal HC, Herfindal M, Mori Y, Jore S, Lund-Johansen F, Fretheim A, Bretthauer M, Kalager M, TRAiN study group (2021)
Covid-19 transmission in fitness centers in Norway - a randomized trial
BMC Public Health, 21 (1), 2103
DOI 10.1186/s12889-021-12073-0, PubMed 34789188

Jodal HC, Klotz D, Herfindal M, Barua I, Tag P, Helsingen LM, Refsum E, Holme Ø, Adami HO, Bretthauer M, Kalager M, Løberg M (2021)
Long-term colorectal cancer incidence and mortality after adenoma removal in women and men
Aliment Pharmacol Ther, 55 (4), 412-421
DOI 10.1111/apt.16686, PubMed 34716941

Juul FE, Jodal HC, Barua I, Refsum E, Olsvik Ø, Helsingen LM, Løberg M, Bretthauer M, Kalager M, Emilsson L (2021)
Mortality in Norway and Sweden during the COVID-19 pandemic
Scand J Public Health, 50 (1), 38-45
DOI 10.1177/14034948211047137, PubMed 34609261

Mori Y, Bretthauer M (2021)
Addressing false-positive findings with artificial intelligence for polyp detection
Endoscopy, 53 (9), 941-942
DOI 10.1055/a-1381-7849, PubMed 34438457

Mori Y, Bretthauer M, Kalager M (2021)
Hopes and Hypes for Artificial Intelligence in Colorectal Cancer Screening
Gastroenterology, 161 (3), 774-777
DOI 10.1053/j.gastro.2021.04.078, PubMed 33989659

Mori Y, Neumann H, Misawa M, Kudo SE, Bretthauer M (2021)
Artificial intelligence in colonoscopy - Now on the market. What's next?
J Gastroenterol Hepatol, 36 (1), 7-11
DOI 10.1111/jgh.15339, PubMed 33179322

Schult AL, Botteri E, Hoff G, Holme Ø, Bretthauer M, Randel KR, Gulichsen EH, El-Safadi B, Barua I, Munck C, Nilsen LR, Svendsen HM, de Lange T (2021)
Women require routine opioids to prevent painful colonoscopies: a randomised controlled trial
Scand J Gastroenterol, 56 (12), 1480-1489
DOI 10.1080/00365521.2021.1969683, PubMed 34534048

Tønnesen CJ, Hjelmesæth J, Hofsø D, Tonstad S, Hertel JK, Heggen E, Johnson LK, Mathisen TE, Kalager M, Wieszczy P, Medhus AW, Løberg M, Aabakken L, Bretthauer M (2021)
A novel intragastric balloon for treatment of obesity and type 2 diabetes. A two-center pilot trial
Scand J Gastroenterol, 57 (2), 232-238
DOI 10.1080/00365521.2021.1994641, PubMed 34714203

Usher-Smith JA, Mills KM, Riedinger C, Saunders CL, Helsingen LM, Lytvyn L, Buskermolen M, Lansdorp-Vogelaar I, Bretthauer M, Guyatt G, Griffin SJ (2021)
The impact of information about different absolute benefits and harms on intention to participate in colorectal cancer screening: A think-aloud study and online randomised experiment
PLoS One, 16 (2), e0246991
DOI 10.1371/journal.pone.0246991, PubMed 33592037

Waldmann E, Kammerlander AA, Gessl I, Penz D, Majcher B, Hinterberger A, Bretthauer M, Trauner MH, Ferlitsch M (2021)
Association of Adenoma Detection Rate and Adenoma Characteristics With Colorectal Cancer Mortality After Screening Colonoscopy
Clin Gastroenterol Hepatol, 19 (9), 1890-1898
DOI 10.1016/j.cgh.2021.04.023, PubMed 33878471

Wieszczy P, Kaminski MF, Løberg M, Bugajski M, Bretthauer M, Kalager M (2021)
Estimation of overdiagnosis in colorectal cancer screening with sigmoidoscopy and faecal occult blood testing: comparison of simulation models
BMJ Open, 11 (4), e042158
DOI 10.1136/bmjopen-2020-042158, PubMed 33853794

Publications 2020

Adami HO, Bretthauer M, Kalager M (2020)
Assessment of cancer screening effectiveness in the era of screening programs
Eur J Epidemiol, 35 (10), 891-897
DOI 10.1007/s10654-020-00684-7, PubMed 32929645

Barua I, Berset IP, Haere P, Wensaas KA, Bretthauer M (2020)
National Screening Program for Bowel Cancer
Tidsskr. Nor. Laegeforen., 140 (3), 222

Barua I, Berset IP, Hære P, Wensaas KA, Bretthauer M (2020)
[National screening programme for colorectal cancer]
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.19.0658, PubMed 32105033

Barua I, Mori Y, Bretthauer M (2020)
Colorectal polyp characterization with endocytoscopy: Ready for widespread implementation with artificial intelligence?
Best Pract Res Clin Gastroenterol, 52-53, 101721
DOI 10.1016/j.bpg.2020.101721, PubMed 34172248

Barua I, Vinsard DG, Jodal HC, Løberg M, Kalager M, Holme Ø, Misawa M, Bretthauer M, Mori Y (2020)
Artificial intelligence for polyp detection during colonoscopy: a systematic review and meta-analysis
Endoscopy, 53 (3), 277-284
DOI 10.1055/a-1201-7165, PubMed 32557490

Bretthauer M, Helsingen LM, Kalager M, Vandvik PO, Agoritsas T, Guyatt G (2020)
The future of colorectal cancer screening: Parentalism or shared decision-making?
CMAJ, 192 (18), E484
DOI 10.1503/cmaj.74839, PubMed 32366471

Bretthauer M, Kalager M (2020)
Disparities in Preventive Health Services: Targeting Minorities and Majorities
Ann Intern Med, 172 (4), 287-288
DOI 10.7326/M19-3899, PubMed 31931529

Bretthauer M, Kalager M, Weinberg DS (2020)
Colorectal Cancer Screening in Young Adults: About Carcinoid Tumors and Cancer
Ann Intern Med, 174 (2), 263-264
DOI 10.7326/M20-7244, PubMed 33315472

Hassan C, Antonelli G, Dumonceau JM, Regula J, Bretthauer M, Chaussade S, Dekker E, Ferlitsch M, Gimeno-Garcia A, Jover R, Kalager M, Pellisé M, Pox C, Ricciardiello L, Rutter M, Helsingen LM, Bleijenberg A, Senore C, van Hooft JE, Dinis-Ribeiro M, Quintero E (2020)
Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2020
Endoscopy, 52 (8), 687-700
DOI 10.1055/a-1185-3109, PubMed 32572858

Helsingen LM, Refsum E, Gjøstein DK, Løberg M, Bretthauer M, Kalager M, Emilsson L, Clinical Effectiveness Research group (2020)
The COVID-19 pandemic in Norway and Sweden - threats, trust, and impact on daily life: a comparative survey
BMC Public Health, 20 (1), 1597
DOI 10.1186/s12889-020-09615-3, PubMed 33097011

Helsingen LM, Zeng L, Siemieniuk RA, Lytvyn L, Vandvik PO, Agoritsas T, Bretthauer M, Guyatt G (2020)
Establishing thresholds for important benefits considering the harms of screening interventions
BMJ Open, 10 (12), e037854
DOI 10.1136/bmjopen-2020-037854, PubMed 33268400

Holme Ø, Kalager M, Bretthauer M, Adami HO, Helsingen L, Løberg M (2020)
Ongoing Trials Will Not Determine the Comparative Effectiveness of Colorectal Cancer Screening Tests
Gastroenterology, 164 (6), 856-860
DOI 10.1053/j.gastro.2020.02.071, PubMed 32585308

Kalager M, Bretthauer M (2020)
Improving cancer screening programs
Science, 367 (6474), 143-144
DOI 10.1126/science.aay3156, PubMed 31919207

Loberg M, Bretthauer M (2020)
Presentation of numbers: do let that fool you
Tidsskr. Nor. Laegeforen., 140 (8), 738

Løberg M, Bretthauer M (2020)
[Presentation of figures: don’t be fooled]
Tidsskr Nor Laegeforen, 140 (8)
DOI 10.4045/tidsskr.20.0378, PubMed 32463198

Mori Y, Kudo SE, East JE, Rastogi A, Bretthauer M, Misawa M, Sekiguchi M, Matsuda T, Saito Y, Ikematsu H, Hotta K, Ohtsuka K, Kudo T, Mori K (2020)
Cost savings in colonoscopy with artificial intelligence-aided polyp diagnosis: an add-on analysis of a clinical trial (with video)
Gastrointest Endosc, 92 (4), 905-911.e1
DOI 10.1016/j.gie.2020.03.3759, PubMed 32240683

Pedersen IB, Bretthauer M, Kalager M, Løberg M, Hoff G, Matapour S, Hugin S, Frigstad SO, Seip B, Kleist BA, Løvdal L, Botteri E, Holme Ø (2020)
Incomplete endoscopic resection of colorectal polyps: a prospective quality assurance study
Endoscopy, 53 (4), 383-391
DOI 10.1055/a-1243-0379, PubMed 32961579

Randel KR, Schult AL, Botteri E, Hoff G, Bretthauer M, Ursin G, Natvig E, Berstad P, Jørgensen A, Sandvei PK, Olsen ME, Frigstad SO, Darre-Næss O, Norvard ER, Bolstad N, Kørner H, Wibe A, Wensaas KA, de Lange T, Holme Ø (2020)
Colorectal Cancer Screening With Repeated Fecal Immunochemical Test Versus Sigmoidoscopy: Baseline Results From a Randomized Trial
Gastroenterology, 160 (4), 1085-1096.e5
DOI 10.1053/j.gastro.2020.11.037, PubMed 33227280

Rutter MD, Bretthauer M, Hassan C, Jover R, WEO Surveillance Working Group (2020)
Principles for Evaluation of Surveillance After Removal of Colorectal Polyps: Recommendations From the World Endoscopy Organization
Gastroenterology, 158 (6), 1529-1533.e4
DOI 10.1053/j.gastro.2019.12.052, PubMed 32240700

Tønnesen CJ, Young J, Glomsaker T, Mala T, Løberg M, Bretthauer M, Refsum E, Aabakken L (2020)
Laparoscopy-assisted versus balloon enteroscopy-assisted ERCP after Roux-en-Y gastric bypass
Endoscopy, 52 (8), 654-661
DOI 10.1055/a-1139-9313, PubMed 32316042

Wieszczy P, Waldmann E, Løberg M, Regula J, Rupinski M, Bugajski M, Gray K, Kalager M, Ferlitsch M, Kaminski MF, Bretthauer M (2020)
Colonoscopist Performance and Colorectal Cancer Risk After Adenoma Removal to Stratify Surveillance: Two Nationwide Observational Studies
Gastroenterology, 160 (4), 1067-1074.e6
DOI 10.1053/j.gastro.2020.10.009, PubMed 33065063

Zeng L, Helsingen LM, Kenji Nampo F, Wang Y, Yao L, Siemieniuk RA, Bretthauer M, Guyatt GH (2020)
How do cancer screening guidelines trade off benefits versus harms and burdens of screening? A systematic survey
BMJ Open, 10 (12), e038322
DOI 10.1136/bmjopen-2020-038322, PubMed 33268404

Zimmermann-Fraedrich K, Pohl H, Rösch T, Rex DK, Hassan C, Dekker E, Kaminski MF, Bretthauer M, de Heer J, Werner Y, Schachschal G, Groth S (2020)
Designs of colonoscopic adenoma detection trials: more positive results with tandem than with parallel studies - an analysis of studies on imaging techniques and mechanical devices
Gut, 70 (2), 268-275
DOI 10.1136/gutjnl-2020-320984, PubMed 32409588

Publications 2019

Adami HO, Kalager M, Valdimarsdottir U, Bretthauer M, Ioannidis JPA (2019)
Time to abandon early detection cancer screening
Eur J Clin Invest, 49 (3), e13062
DOI 10.1111/eci.13062, PubMed 30565674

Adami HO, Kalager M, Valdimarsdottir U, Bretthauer M, Ioannidis JPA (2019)
Author Reply to: The name of the game: Is preventive screening "cancer screening?"
Eur J Clin Invest, 49 (6), e13097
DOI 10.1111/eci.13097, PubMed 30829396

Bleijenberg A, Klotz D, Løberg M, Dekker E, Adami HO, Kuipers EJ, Holme Ø, Kalager M, Emilsson L, Kleist B, Løvdal L, Regula J, Løberg EM, IJspeert J, Bretthauer M (2019)
Implications of different guidelines for surveillance after serrated polyp resection in United States of America and Europe
Endoscopy, 51 (8), 750-758
DOI 10.1055/a-0916-8598, PubMed 31195423

Bretthauer M (2019)
Detection rates during colonoscopy: What matters most?
Endoscopy, 52 (1), 15-16
DOI 10.1055/a-1058-8854, PubMed 31853929

Bretthauer M, Kalager M, Weinberg DS (2019)
From Colorectal Cancer Screening Guidelines to Headlines: Beware!
Ann Intern Med, 170 (10), 734
DOI 10.7326/L19-0086, PubMed 31108525

Bugajski M, Wieszczy P, Pisera M, Rupinski M, Hoff G, Huppertz-Hauss G, Regula J, Bretthauer M, Kaminski MF (2019)
Effectiveness of digital feedback on patient experience and 30-day complications after screening colonoscopy: a randomized health services study
Endosc Int Open, 7 (4), E537-E544
DOI 10.1055/a-0830-4648, PubMed 31041371

Buskermolen M, Cenin DR, Helsingen LM, Guyatt G, Vandvik PO, Haug U, Bretthauer M, Lansdorp-Vogelaar I (2019)
Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a microsimulation modelling study
BMJ, 367, l5383
DOI 10.1136/bmj.l5383, PubMed 31578177

García-Albéniz X, Hsu J, Bretthauer M, Hernán MA (2019)
Estimating the Effect of Preventive Services With Databases of Administrative Claims: Reasons to Be Concerned
Am J Epidemiol, 188 (10), 1764-1767
DOI 10.1093/aje/kwz049, PubMed 30869122

Hassan C, East J, Radaelli F, Spada C, Benamouzig R, Bisschops R, Bretthauer M, Dekker E, Dinis-Ribeiro M, Ferlitsch M, Fuccio L, Awadie H, Gralnek I, Jover R, Kaminski MF, Pellisé M, Triantafyllou K, Vanella G, Mangas-Sanjuan C, Frazzoni L, Van Hooft JE, Dumonceau JM (2019)
Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2019
Endoscopy, 51 (8), 775-794
DOI 10.1055/a-0959-0505, PubMed 31295746

Helsingen LM, Vandvik PO, Jodal HC, Agoritsas T, Lytvyn L, Anderson JC, Auer R, Murphy SB, Almadi MA, Corley DA, Quinlan C, Fuchs JM, McKinnon A, Qaseem A, Heen AF, Siemieniuk RAC, Kalager M, Usher-Smith JA, Lansdorp-Vogelaar I, Bretthauer M, Guyatt G (2019)
Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a clinical practice guideline
BMJ, 367, l5515
DOI 10.1136/bmj.l5515, PubMed 31578196

Helsingen LM, Vandvik PO, Jodal HC, Murphy SB, Heen AF, Kalager M, Bretthauer M (2019)
[Colorectal cancer screening, yes or no?]
Tidsskr Nor Laegeforen, 139 (15)
DOI 10.4045/tidsskr.19.0323, PubMed 31642636

Helsingen LM, Vandvik PO, Jodal HC, Murphy SB, Heen AF, Kalager M, Bretthauer M (2019)
Colorectal cancer screening, right?
Tidsskr. Nor. Laegeforen., 139 (15), 1450-1451

Hoff G, Botteri E, Høie O, Garborg K, Wiig H, Huppertz-Hauss G, Moritz V, Bretthauer M, Holme Ø (2019)
Polyp detection rates as quality indicator in clinical versus screening colonoscopy
Endosc Int Open, 7 (2), E195-E202
DOI 10.1055/a-0796-6477, PubMed 30705953

Hoff G, de Lange T, Bretthauer M, Dahler S, Halvorsen FA, Huppertz-Hauss G, Høie O, Kjellevold Ø, Mortiz V, Sandvei P, Seip B, Holme Ø (2019)
Registration bias in a clinical quality register
Endosc Int Open, 7 (1), E90-E98
DOI 10.1055/a-0806-7006, PubMed 30652120

Holme Ø, Bretthauer M, Løberg M, Kalager M, Adami HO (2019)
Revisiting surveillance schemes for cancer survivors
Ann Oncol, 30 (6), 881-883
DOI 10.1093/annonc/mdz107, PubMed 30895293

Holme Ø, Bretthauer M, Løberg M, Kalager M, Adami HO (2019)
Reply to the letter to the editor 'Cancer survivors: surveillance or not surveillance?' by Santeufemia and Miolo
Ann Oncol, 30 (9), 1531-1532
DOI 10.1093/annonc/mdz190, PubMed 31198953

Randel KR, Botteri E, Romstad KMK, Frigstad SO, Bretthauer M, Hoff G, de Lange T, Holme Ø (2019)
Effects of Oral Anticoagulants and Aspirin on Performance of Fecal Immunochemical Tests in Colorectal Cancer Screening
Gastroenterology, 156 (6), 1642-1649.e1
DOI 10.1053/j.gastro.2019.01.040, PubMed 30689972

Spada C, McNamara D, Despott EJ, Adler S, Cash BD, Fernández-Urién I, Ivekovic H, Keuchel M, McAlindon M, Saurin JC, Panter S, Bellisario C, Minozzi S, Senore C, Bennett C, Bretthauer M, Dinis-Ribeiro M, Domagk D, Hassan C, Kaminski MF, Rees CJ, Valori R, Bisschops R, Rutter MD (2019)
Performance measures for small-bowel endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
Endoscopy, 51 (6), 574-598
DOI 10.1055/a-0889-9586, PubMed 31075800

Spada C, McNamara D, Despott EJ, Adler S, Cash BD, Fernández-Urién I, Ivekovic H, Keuchel M, McAlindon M, Saurin JC, Panter S, Bellisario C, Minozzi S, Senore C, Bennett C, Bretthauer M, Dinis-Ribeiro M, Domagk D, Hassan C, Kaminski MF, Rees CJ, Valori R, Bisschops R, Rutter MD (2019)
Performance measures for small-bowel endoscopy: A European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
United European Gastroenterol J, 7 (5), 614-641
DOI 10.1177/2050640619850365, PubMed 31210941

Spadaccini M, Frazzoni L, Vanella G, East J, Radaelli F, Spada C, Fuccio L, Benamouzig R, Bisschops R, Bretthauer M, Dekker E, Dinis-Ribeiro M, Ferlitsch M, Gralnek I, Jover R, Kaminski MF, Pellisé M, Triantafyllou K, Van Hooft JE, Dumonceau JM, Marmo C, Alfieri S, Chandrasekar VT, Sharma P, Rex DK et al. (2019)
Efficacy and Tolerability of High- vs Low-Volume Split-Dose Bowel Cleansing Regimens for Colonoscopy: A Systematic Review and Meta-analysis
Clin Gastroenterol Hepatol, 18 (7), 1454-1465.e14
DOI 10.1016/j.cgh.2019.10.044, PubMed 31683057

Wieszczy P, Kaminski MF, Franczyk R, Loberg M, Kobiela J, Rupinska M, Kocot B, Rupinski M, Holme O, Wojciechowska U, Didkowska J, Ransohoff D, Bretthauer M, Kalager M, Regula J (2019)
Colorectal Cancer Incidence and Mortality After Removal of Adenomas During Screening Colonoscopies
Gastroenterology, 158 (4), 875-883.e5
DOI 10.1053/j.gastro.2019.09.011, PubMed 31563625

Publications 2018

Bretthauer M (2018)
[Screening for melanoma is a poor idea]
Tidsskr Nor Laegeforen, 138 (17)
DOI 10.4045/tidsskr.18.0600, PubMed 30378406

Bretthauer M (2018)
Screening for melanoma is a bad idea
Tidsskr. Nor. Laegeforen., 138 (17), 1589

Bretthauer M, Goderstad JM, Løberg M, Emilsson L, Ye W, Adami HO, Kalager M (2018)
Uterine morcellation and survival in uterine sarcomas
Eur J Cancer, 101, 62-68
DOI 10.1016/j.ejca.2018.06.007, PubMed 30025231

Bretthauer M, Kalager M (2018)
When no guideline recommendation is the best recommendation
Lancet, 392 (10151), 898-899
DOI 10.1016/S0140-6736(18)31671-4, PubMed 30238877

Bretthauer M, Kalager M, Weinberg DS (2018)
From Colorectal Cancer Screening Guidelines to Headlines: Beware!
Ann Intern Med, 169 (6), 405-406
DOI 10.7326/M18-1720, PubMed 29987330

Domagk D, Oppong KW, Aabakken L, Czakó L, Gyökeres T, Manes G, Meier P, Poley JW, Ponchon T, Tringali A, Bellisario C, Minozzi S, Senore C, Bennett C, Bretthauer M, Hassan C, Kaminski MF, Dinis-Ribeiro M, Rees CJ, Spada C, Valori R, Bisschops R, Rutter MD (2018)
Performance measures for ERCP and endoscopic ultrasound: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
Endoscopy, 50 (11), 1116-1127
DOI 10.1055/a-0749-8767, PubMed 30340220

Domagk D, Oppong KW, Aabakken L, Czakó L, Gyökeres T, Manes G, Meier P, Poley JW, Ponchon T, Tringali A, Bellisario C, Minozzi S, Senore C, Bennett C, Bretthauer M, Hassan C, Kaminski MF, Dinis-Ribeiro M, Rees CJ, Spada C, Valori R, Bisschops R, Rutter MD (2018)
Performance measures for endoscopic retrograde cholangiopancreatography and endoscopic ultrasound: A European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
United European Gastroenterol J, 6 (10), 1448-1460
DOI 10.1177/2050640618808157, PubMed 30574315

Halvorsen JA, Løberg M, Gjersvik P, Roscher I, Veierød MB, Robsahm TE, Nilsen LTN, Kalager M, Bretthauer M (2018)
Why a randomized melanoma screening trial is not a good idea
Br J Dermatol, 179 (2), 532-533
DOI 10.1111/bjd.16784, PubMed 29893490

Holme Ø, Løberg M, Kalager M, Bretthauer M, Hernán MA, Aas E, Eide TJ, Skovlund E, Lekven J, Schneede J, Tveit KM, Vatn M, Ursin G, Hoff G, NORCCAP Study Group† (2018)
Long-Term Effectiveness of Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality in Women and Men: A Randomized Trial
Ann Intern Med, 168 (11), 775-782
DOI 10.7326/M17-1441, PubMed 29710125

Holme Ø, Løberg M, Kalager M, Bretthauer M, Hoff G (2018)
Long-Term Effectiveness of Sigmoidoscopy Screening in Women and Men
Ann Intern Med, 169 (9), 663-664
DOI 10.7326/L18-0512, PubMed 30398636

Holme Ø, Pedersen IB, Medhus AW, Aabakken L, Glomsaker T, Kvamme JM, Løberg M, Bretthauer M, Seip B, Kjellevold Ø, Jørgensen A, Furholm S, Hoff G, de Lange T (2018)
Endoscopy assistants influence the quality of colonoscopy
Endoscopy, 50 (9), 871-877
DOI 10.1055/s-0044-101706, PubMed 29444529

Jodal HC, Løberg M, Holme Ø, Adami HO, Bretthauer M, Emilsson L, Ransohoff DF, Hoff G, Kalager M (2018)
Mortality From Postscreening (Interval) Colorectal Cancers Is Comparable to That From Cancer in Unscreened Patients-A Randomized Sigmoidoscopy Trial
Gastroenterology, 155 (6), 1787-1794.e3
DOI 10.1053/j.gastro.2018.08.035, PubMed 30165051

Juul FE, Garborg K, Bretthauer M, Skudal H, Øines MN, Wiig H, Rose Ø, Seip B, Lamont JT, Midtvedt T, Valeur J, Kalager M, Holme Ø, Helsingen L, Løberg M, Adami HO (2018)
Fecal Microbiota Transplantation for Primary Clostridium difficile Infection
N Engl J Med, 378 (26), 2535-2536
DOI 10.1056/NEJMc1803103, PubMed 29860912

Kalager M, Wieszczy P, Lansdorp-Vogelaar I, Corley DA, Bretthauer M, Kaminski MF (2018)
Overdiagnosis in Colorectal Cancer Screening: Time to Acknowledge a Blind Spot
Gastroenterology, 155 (3), 592-595
DOI 10.1053/j.gastro.2018.07.037, PubMed 30076834

Pedersen IB, Løberg M, Hoff G, Kalager M, Bretthauer M, Holme Ø (2018)
Polypectomy techniques among gastroenterologists in Norway - a nationwide survey
Endosc Int Open, 6 (7), E812-E820
DOI 10.1055/a-0607-0727, PubMed 29977999

Pinsky PF, Loberg M, Senore C, Wooldrage K, Atkin W, Bretthauer M, Cross AJ, Hoff G, Holme O, Kalager M, Segnan N, Schoen RE (2018)
Number of Adenomas Removed and Colorectal Cancers Prevented in Randomized Trials of Flexible Sigmoidoscopy Screening
Gastroenterology, 155 (4), 1059-1068.e2
DOI 10.1053/j.gastro.2018.06.040, PubMed 29935150

Valori R, Cortas G, de Lange T, Balfaqih OS, de Pater M, Eisendrath P, Falt P, Koruk I, Ono A, Rustemović N, Schoon E, Veitch A, Senore C, Bellisario C, Minozzi S, Bennett C, Bretthauer M, Dinis-Ribeiro M, Domagk D, Hassan C, Kaminski MF, Rees CJ, Spada C, Bisschops R, Rutter M (2018)
Performance measures for endoscopy services: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
Endoscopy, 50 (12), 1186-1204
DOI 10.1055/a-0755-7515, PubMed 30423593

Valori R, Cortas G, de Lange T, Salem Balfaqih O, de Pater M, Eisendrath P, Falt P, Koruk I, Ono A, Rustemović N, Schoon E, Veitch A, Senore C, Bellisario C, Minozzi S, Bennett C, Bretthauer M, Dinis-Ribeiro M, Domagk D, Hassan C, Kaminski MF, Rees CJ, Spada C, Bisschops R, Rutter M (2018)
Performance measures for endoscopy services: A European Society of Gastrointestinal Endoscopy (ESGE) quality improvement initiative
United European Gastroenterol J, 7 (1), 21-44
DOI 10.1177/2050640618810242, PubMed 30788114

Publications 2017

Brandrud AS, Bretthauer M, Brattebø G, Pedersen MJ, Håpnes K, Møller K, Bjorge T, Nyen B, Strauman L, Schreiner A, Haldorsen GS, Bergli M, Nelson E, Morgan TS, Hjortdahl P (2017)
Local emergency medical response after a terrorist attack in Norway: a qualitative study
BMJ Qual Saf, 26 (10), 806-816
DOI 10.1136/bmjqs-2017-006517, PubMed 28676492

Brandrud AS, Nyen B, Hjortdahl P, Sandvik L, Helljesen Haldorsen GS, Bergli M, Nelson EC, Bretthauer M (2017)
Domains associated with successful quality improvement in healthcare - a nationwide case study
BMC Health Serv Res, 17 (1), 648
DOI 10.1186/s12913-017-2454-2, PubMed 28903723

Bretthauer M (2017)
[Data sharing]
Tidsskr Nor Laegeforen, 137 (10), 738
DOI 10.4045/tidsskr.17.0366, PubMed 28551975

Bretthauer M (2017)
[Correct and proper critical pathway]
Tidsskr Nor Laegeforen, 137 (17)
DOI 10.4045/tidsskr.17.0510, PubMed 28925233

Bretthauer M (2017)
Right and correct package
Tidsskr. Nor. Laegeforen., 137 (17), 1264

Bretthauer M, Adami HO (2017)
[Not Available]
Tidsskr Nor Laegeforen, 137 (20)
DOI 10.4045/tidsskr.17.0875, PubMed 29094556

Bretthauer M, Adami HO (2017)
Doubt
Tidsskr. Nor. Laegeforen., 137 (20), 1577-1578

Bretthauer M, Dinis-Ribeiro M, Siersema PD (2017)
Foreword
Endoscopy, 49 (3), 213
DOI 10.1055/s-0043-102442, PubMed 28249316

Bretthauer M, Kaminski MF, Emilsson L, Adami HO (2017)
[Not Available]
Lakartidningen, 114
PubMed 28696487

Bretthauer M, Vandvik PO, Skjeldestad FE, Frich JC, de Lange T, Loberg M (2017)
New specialist education for doctors- from Swiss cheese to Kraftkar?
Tidsskr. Nor. Laegeforen., 137 (17), 1270-1271

Bretthauer M, Vandvik PO, Skjeldestad FE, Frich JC, Lange T, Løberg M (2017)
[New specialist training for physicians - from Swiss cheese to strongman?]
Tidsskr Nor Laegeforen, 137 (17)
DOI 10.4045/tidsskr.17.0637, PubMed 28925200

Emilsson L, Løberg M, Bretthauer M, Holme Ø, Fall K, Jodal HC, Adami HO, Kalager M (2017)
Colorectal cancer death after adenoma removal in Scandinavia
Scand J Gastroenterol, 52 (12), 1377-1384
DOI 10.1080/00365521.2017.1377763, PubMed 28906163

Garborg K, de Lange T, Bretthauer M (2017)
Quality Indicators in Colonoscopy
Curr Treat Options Gastroenterol, 15 (3), 416-428
DOI 10.1007/s11938-017-0140-4, PubMed 28702775

García-Albéniz X, Hsu J, Bretthauer M, Hernán MA (2017)
Screening Colonoscopy to Prevent Colorectal Cancer Among Medicare Beneficiaries Aged 70 to 79 Years
Ann Intern Med, 166 (10), 758-759
DOI 10.7326/L17-0138, PubMed 28505646

Hoff G, de Lange T, Bretthauer M, Buset M, Dahler S, Halvorsen FA, Halwe JM, Heibert M, Høie O, Kjellevold Ø, Moritz V, Sandvei P, Seip B, Aabakken L, Holme Ø (2017)
Patient-reported adverse events after colonoscopy in Norway
Endoscopy, 49 (8), 745-753
DOI 10.1055/s-0043-105265, PubMed 28445903

Hoff G, Holme Ø, Bretthauer M, Sandvei P, Darre-Næss O, Stallemo A, Wiig H, Høie O, Noraberg G, Moritz V, de Lange T (2017)
Cecum intubation rate as quality indicator in clinical versus screening colonoscopy
Endosc Int Open, 5 (6), E489-E495
DOI 10.1055/s-0043-106180, PubMed 28573182

Holme Ø, Løberg M, Bretthauer M, Kalager M (2017)
Authors' reply to Doherty and Hawkins
BMJ, 356, j1267
DOI 10.1136/bmj.j1267, PubMed 28283482

Holme Ø, Schoen RE, Senore C, Segnan N, Hoff G, Løberg M, Bretthauer M, Adami HO, Kalager M (2017)
Effectiveness of flexible sigmoidoscopy screening in men and women and different age groups: pooled analysis of randomised trials
BMJ, 356, i6673
DOI 10.1136/bmj.i6673, PubMed 28087510

Kaminski MF, Thomas-Gibson S, Bugajski M, Bretthauer M, Rees CJ, Dekker E, Hoff G, Jover R, Suchanek S, Ferlitsch M, Anderson J, Roesch T, Hultcranz R, Racz I, Kuipers EJ, Garborg K, East JE, Rupinski M, Seip B, Bennett C, Senore C, Minozzi S, Bisschops R, Domagk D, Valori R et al. (2017)
Performance measures for lower gastrointestinal endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
Endoscopy, 49 (4), 378-397
DOI 10.1055/s-0043-103411, PubMed 28268235

Kaminski MF, Thomas-Gibson S, Bugajski M, Bretthauer M, Rees CJ, Dekker E, Hoff G, Jover R, Suchanek S, Ferlitsch M, Anderson J, Roesch T, Hultcranz R, Racz I, Kuipers EJ, Garborg K, East JE, Rupinski M, Seip B, Bennett C, Senore C, Minozzi S, Bisschops R, Domagk D, Valori R et al. (2017)
Performance measures for lower gastrointestinal endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) quality improvement initiative
United European Gastroenterol J, 5 (3), 309-334
DOI 10.1177/2050640617700014, PubMed 28507745

Lange T, Randel KR, Schult AL, Knudsen MD, Kirkøen B, Botteri E, Berstad P, Jørgensen A, Ursin G, Bretthauer M, Hoff G (2017)
Sigmoidoscopy and faecal occult blood test - a comparative screening trial
Tidsskr Nor Laegeforen, 137 (10), 727-730
DOI 10.4045/tidsskr.16.1031, PubMed 28551972

Løberg M, Holme Ø, Bretthauer M, Kalager M (2017)
Colorectal adenomas, surveillance, and cancer
Lancet Oncol, 18 (8), e427
DOI 10.1016/S1470-2045(17)30473-4, PubMed 28759374

Olsen SE, Bretthauer M, Kalager M (2017)
[More harm than benefit - how much should the patients know?]
Tidsskr Nor Laegeforen, 137 (3), 175-176
DOI 10.4045/tidsskr.16.0954, PubMed 28181749

Olsen SE, Bretthauer M, Kalager M (2017)
[Not Available]
Tidsskr Nor Laegeforen, 137 (9), 599
DOI 10.4045/tidsskr.17.0296, PubMed 28468459

Olsen SE, Bretthauer M, Kalager M (2017)
More harm than benefit - how much should the patients know? Reply
Tidsskr. Nor. Laegeforen., 137 (9), 599

Øines M, Helsingen LM, Bretthauer M, Emilsson L (2017)
Epidemiology and risk factors of colorectal polyps
Best Pract Res Clin Gastroenterol, 31 (4), 419-424
DOI 10.1016/j.bpg.2017.06.004, PubMed 28842051

Publications 2016

Adami HO, Bretthauer M, Emilsson L, Hernán MA, Kalager M, Ludvigsson JF, Ekbom A (2016)
The continuing uncertainty about cancer risk in inflammatory bowel disease
Gut, 65 (6), 889-93
DOI 10.1136/gutjnl-2015-311003, PubMed 27008845

Adami HO, Csermely P, Veres DV, Emilsson L, Løberg M, Bretthauer M, Kalager M (2016)
Are rapidly growing cancers more lethal?
Eur J Cancer, 72, 210-214
DOI 10.1016/j.ejca.2016.11.011, PubMed 28042992

Berstad P, Botteri E, Larsen IK, Løberg M, Kalager M, Holme Ø, Bretthauer M, Hoff G (2016)
Lifestyle changes at middle age and mortality: a population-based prospective cohort study
J Epidemiol Community Health, 71 (1), 59-66
DOI 10.1136/jech-2015-206760, PubMed 27312250

Bisschops R, Areia M, Coron E, Dobru D, Kaskas B, Kuvaev R, Pech O, Ragunath K, Weusten B, Familiari P, Domagk D, Valori R, Kaminski MF, Spada C, Bretthauer M, Bennett C, Senore C, Dinis-Ribeiro M, Rutter MD (2016)
Performance measures for upper gastrointestinal endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative
Endoscopy, 48 (9), 843-64
DOI 10.1055/s-0042-113128, PubMed 27548885

Bisschops R, Areia M, Coron E, Dobru D, Kaskas B, Kuvaev R, Pech O, Ragunath K, Weusten B, Familiari P, Domagk D, Valori R, Kaminski MF, Spada C, Bretthauer M, Bennett C, Senore C, Dinis-Ribeiro M, Rutter MD (2016)
Performance measures for upper gastrointestinal endoscopy: A European Society of Gastrointestinal Endoscopy quality improvement initiative
United European Gastroenterol J, 4 (5), 629-656
DOI 10.1177/2050640616664843, PubMed 27733906

Bretthauer M, Hem E (2016)
[M. Bretthauer & E. Hem reply]
Tidsskr Nor Laegeforen, 136 (1), 10
DOI 10.4045/tidsskr.15.1307, PubMed 26757645

Bretthauer M, Hem E (2016)
Circumcision of boys Reply
Tidsskr. Nor. Laegeforen., 136 (1), 10

Bretthauer M, Kalager M, Adami HO, Hoff G (2016)
Who Is for CO2? Slow Adoption of Carbon Dioxide Insufflation in Colonoscopy
Ann Intern Med, 165 (2), 145-6
DOI 10.7326/M16-0209, PubMed 27159139

Bretthauer M, Kaminski MF, Hassan C, Kalager M, Holme Ø, Hoff G, Løberg M, Regula J, Castells A, Adami HO (2016)
America, We Are Confused: The Updated U.S. Preventive Services Task Force Recommendation on Colorectal Cancer Screening
Ann Intern Med, 166 (2), 139-140
DOI 10.7326/M16-1805, PubMed 27820949

Bretthauer M, Kaminski MF, Løberg M, Zauber AG, Regula J, Kuipers EJ, Hernán MA, McFadden E, Sunde A, Kalager M, Dekker E, Lansdorp-Vogelaar I, Garborg K, Rupinski M, Spaander MC, Bugajski M, Høie O, Stefansson T, Hoff G, Adami HO, Nordic-European Initiative on Colorectal Cancer (NordICC) Study Group (2016)
Population-Based Colonoscopy Screening for Colorectal Cancer: A Randomized Clinical Trial
JAMA Intern Med, 176 (7), 894-902
DOI 10.1001/jamainternmed.2016.0960, PubMed 27214731

Bretthauer M, Schei E (2016)
[Not Available]
Tidsskr Nor Laegeforen, 136 (1), 24-6
DOI 10.4045/tidsskr.15.1257, PubMed 26757655

Bretthauer M, Aabakken L, Dekker E, Kaminski MF, Rösch T, Hultcrantz R, Suchanek S, Jover R, Kuipers EJ, Bisschops R, Spada C, Valori R, Domagk D, Rees C, Rutter MD, ESGE Quality Improvement Committee (2016)
Requirements and standards facilitating quality improvement for reporting systems in gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement
Endoscopy, 48 (3), 291-4
DOI 10.1055/s-0042-100186, PubMed 26841269

Bretthauer M, Aabakken L, Dekker E, Kaminski MF, Rösch T, Hultcrantz R, Suchanek S, Jover R, Kuipers EJ, Bisschops R, Spada C, Valori R, Domagk D, Rees C, Rutter MD, ESGE Quality Improvement Committee (2016)
Reporting systems in gastrointestinal endoscopy: Requirements and standards facilitating quality improvement: European Society of Gastrointestinal Endoscopy position statement
United European Gastroenterol J, 4 (2), 172-6
DOI 10.1177/2050640616629079, PubMed 27087943

Dinis-Ribeiro M, Bretthauer M, Siersema PD (2016)
Endoscopy again supports Colorectal Cancer Awareness Month
Endoscopy, 48 (3), 209
DOI 10.1055/s-0042-102468, PubMed 26906311

Emilsson L, Holme Ø, Bretthauer M, Cook NR, Buring JE, Løberg M, Adami HO, Sesso HD, Gaziano MJ, Kalager M (2016)
Systematic review with meta-analysis: the comparative effectiveness of aspirin vs. screening for colorectal cancer prevention
Aliment Pharmacol Ther, 45 (2), 193-204
DOI 10.1111/apt.13857, PubMed 27859394

Garborg K, Bretthauer M (2016)
Cecal intubation failure: Refer or change technique?
Gastrointest Endosc, 83 (6), 1245-7
DOI 10.1016/j.gie.2015.12.014, PubMed 27206588

Garborg K, Wiig H, Hasund A, Matre J, Holme Ø, Noraberg G, Løberg M, Kalager M, Adami HO, Bretthauer M (2016)
Gradual stiffness versus magnetic imaging-guided variable stiffness colonoscopes: A randomized noninferiority trial
United European Gastroenterol J, 5 (1), 128-133
DOI 10.1177/2050640616639162, PubMed 28405331

García-Albéniz X, Hsu J, Bretthauer M, Hernán MA (2016)
Effectiveness of Screening Colonoscopy to Prevent Colorectal Cancer Among Medicare Beneficiaries Aged 70 to 79 Years: A Prospective Observational Study
Ann Intern Med, 166 (1), 18-26
DOI 10.7326/M16-0758, PubMed 27669524

García-Albéniz X, Hsu J, Lipsitch M, Bretthauer M, Logan RW, Hernández-Díaz S, Hernán MA (2016)
Colonoscopy and Risk of Infective Endocarditis in the Elderly
J Am Coll Cardiol, 68 (5), 570-571
DOI 10.1016/j.jacc.2016.05.041, PubMed 27470461

Gjøstein DK, Bretthauer M, Løberg M (2016)
[Not Available]
Tidsskr Nor Laegeforen, 136 (16), 1326-7
DOI 10.4045/tidsskr.16.0690, PubMed 27637038

Gjøstein DK, Huitfeldt A, Løberg M, Adami HO, Garborg K, Kalager M, Bretthauer M (2016)
Incentives and participation in a medical survey
Tidsskr Nor Laegeforen, 136 (12-13), 1082-7
DOI 10.4045/tidsskr.15.1096, PubMed 27381786

Holme Ø, Bretthauer M (2016)
Pain and sedation during colonoscopy - a never ending story
Endosc Int Open, 4 (5), E538-9
DOI 10.1055/s-0042-106085, PubMed 27227111

Holme Ø, de Lange T, Stallemo A, Wiig H, Hasund A, Dvergsnes K, Garborg K, Ystrøm CM, Løberg M, Hoff G, Bretthauer M, Kalager M (2016)
Routine vs. on-demand analgesia in colonoscopy: a randomized clinical trial
Endoscopy, 48 (9), 823-8
DOI 10.1055/s-0042-108433, PubMed 27305424

Jover R, Bretthauer M, Dekker E, Holme Ø, Kaminski MF, Løberg M, Zauber AG, Hernán MA, Lansdorp-Vogelaar I, Sunde A, McFadden E, Castells A, Regula J, Quintero E, Pellisé M, Senore C, Kalager M, Dinis-Ribeiro M, Emilsson L, Ransohoff DF, Hoff G, Adami HO (2016)
Rationale and design of the European Polyp Surveillance (EPoS) trials
Endoscopy, 48 (6), 571-8
DOI 10.1055/s-0042-104116, PubMed 27042931

Kalager M, Adami HO, Bretthauer M (2016)
Recognizing Data Generation
N Engl J Med, 374 (19), 1898
DOI 10.1056/NEJMc1603789, PubMed 27096437

Kaminski MF, Bretthauer M (2016)
Cancer surveillance in gastroenterology practice
Best Pract Res Clin Gastroenterol, 30 (6), 853-854
DOI 10.1016/j.bpg.2016.10.016, PubMed 27938780

Løberg M, Kalager M, Bretthauer M (2016)
Commentary: "Randomize, Then Consent" or "Consent, Then Randomize"?: Revitalizing the Issue of Preconsent Randomization
Epidemiology, 27 (3), 393-4
DOI 10.1097/EDE.0000000000000469, PubMed 26849639

Rees CJ, Bevan R, Zimmermann-Fraedrich K, Rutter MD, Rex D, Dekker E, Ponchon T, Bretthauer M, Regula J, Saunders B, Hassan C, Bourke MJ, Rösch T (2016)
Expert opinions and scientific evidence for colonoscopy key performance indicators
Gut, 65 (12), 2045-2060
DOI 10.1136/gutjnl-2016-312043, PubMed 27802153

Rees CJ, Ngu WS, Regula J, Bisschops R, Saftoiu A, Dekker E, Gralnek I, Ciocirlan M, Dinis-Ribeiro M, Jover R, Meisner S, Spada C, Hassan C, Valori R, Hucl T, Le Moine O, Domagk D, Kaminski MF, Bretthauer M, Rutter MD, Aabakken L, Ponchon T, Fockens P, Siersema PD (2016)
European Society of Gastrointestinal Endoscopy - Establishing the key unanswered research questions within gastrointestinal endoscopy
Endoscopy, 48 (10), 884-891
DOI 10.1055/s-0042-110398, PubMed 27485483

Publications 2015

Bretthauer M, Hem E (2015)
[Circumcision of boys]
Tidsskr Nor Laegeforen, 135 (21), 1926-7
DOI 10.4045/tidsskr.15.0756, PubMed 26577316

Bretthauer M, Hem E (2015)
[M. Bretthauer & E. Hem reply]
Tidsskr Nor Laegeforen, 135 (23-24), 2130
DOI 10.4045/tidsskr.15.1254, PubMed 26674025

Bretthauer M, Hem E (2015)
Circumcision of boys Reply
Tidsskr. Nor. Laegeforen., 135 (23-24), 2130

Bretthauer M, Kalager M, Adami HO (2015)
Do's and don'ts in evaluation of endoscopic screening for gastrointestinal cancers
Endoscopy, 48 (1), 75-80
DOI 10.1055/s-0034-1393094, PubMed 26382306

Bretthauer M, Siersema PD (2015)
More adenomas - less cancer? Advanced imaging in colonoscopy
Endoscopy, 47 (5), 396-7
DOI 10.1055/s-0034-1391864, PubMed 25910007

Garborg K, Kaminski MF, Bretthauer M (2015)
Reply to Ishaq et al
Endoscopy, 47 (10), 959
DOI 10.1055/s-0034-1392409, PubMed 26417975

Garborg K, Kaminski MF, Bretthauer M (2015)
Water exchange versus carbon dioxide insufflation in unsedated colonoscopy: less is more Reply
Endoscopy, 47 (10), 959

Hassan C, Repici A, Sharma P, Correale L, Zullo A, Bretthauer M, Senore C, Spada C, Bellisario C, Bhandari P, Rex DK (2015)
Efficacy and safety of endoscopic resection of large colorectal polyps: a systematic review and meta-analysis
Gut, 65 (5), 806-20
DOI 10.1136/gutjnl-2014-308481, PubMed 25681402

Kaminski MF, Anderson J, Valori R, Kraszewska E, Rupinski M, Pachlewski J, Wronska E, Bretthauer M, Thomas-Gibson S, Kuipers EJ, Regula J (2015)
Leadership training to improve adenoma detection rate in screening colonoscopy: a randomised trial
Gut, 65 (4), 616-24
DOI 10.1136/gutjnl-2014-307503, PubMed 25670810

Løberg M, Lousdal ML, Bretthauer M, Kalager M (2015)
Benefits and harms of mammography screening
Breast Cancer Res, 17 (1), 63
DOI 10.1186/s13058-015-0525-z, PubMed 25928287

Moritz V, Bretthauer M, Holme Ø, Wang Fagerland M, Løberg M, Glomsaker T, de Lange T, Seip B, Sandvei P, Hoff G (2015)
Time trends in quality indicators of colonoscopy
United European Gastroenterol J, 4 (1), 110-20
DOI 10.1177/2050640615570147, PubMed 26966531

Robertson DJ, Kaminski MF, Bretthauer M (2015)
Effectiveness, training and quality assurance of colonoscopy screening for colorectal cancer
Gut, 64 (6), 982-90
DOI 10.1136/gutjnl-2014-308076, PubMed 25804631

Rutter MD, Senore C, Bisschops R, Domagk D, Valori R, Kaminski MF, Spada C, Bretthauer M, Bennett C, Bellisario C, Minozzi S, Hassan C, Rees C, Dinis-Ribeiro M, Hucl T, Ponchon T, Aabakken L, Fockens P (2015)
The European Society of Gastrointestinal Endoscopy Quality Improvement Initiative: developing performance measures
Endoscopy, 48 (1), 81-9
DOI 10.1055/s-0035-1569580, PubMed 26662057

Rutter MD, Senore C, Bisschops R, Domagk D, Valori R, Kaminski MF, Spada C, Bretthauer M, Bennett C, Bellisario C, Minozzi S, Hassan C, Rees C, Dinis-Ribeiro M, Hucl T, Ponchon T, Aabakken L, Fockens P (2015)
The European Society of Gastrointestinal Endoscopy Quality Improvement Initiative: developing performance measures
United European Gastroenterol J, 4 (1), 30-41
DOI 10.1177/2050640615624631, PubMed 26966520

Spada C, Stoker J, Alarcon O, Barbaro F, Bellini D, Bretthauer M, De Haan MC, Dumonceau JM, Ferlitsch M, Halligan S, Helbren E, Hellstrom M, Kuipers EJ, Lefere P, Mang T, Neri E, Petruzziello L, Plumb A, Regge D, Taylor SA, Hassan C, Laghi A (2015)
Clinical indications for computed tomographic colonography: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline
Eur Radiol, 25 (2), 331-45
DOI 10.1007/s00330-014-3435-z, PubMed 25278245

Swanson SA, Holme Ø, Løberg M, Kalager M, Bretthauer M, Hoff G, Aas E, Hernán MA (2015)
Bounding the per-protocol effect in randomized trials: an application to colorectal cancer screening
Trials, 16, 541
DOI 10.1186/s13063-015-1056-8, PubMed 26620120

Publications 2014

Berstad P, Løberg M, Larsen IK, Kalager M, Holme Ø, Botteri E, Bretthauer M, Hoff G (2014)
Long-term lifestyle changes after colorectal cancer screening: randomised controlled trial
Gut, 64 (8), 1268-76
DOI 10.1136/gutjnl-2014-307376, PubMed 25183203

Bretthauer M, Brandrud AS (2014)
Endoscopy training: time to stop counting procedures?
Gut, 63 (11), 1686-7
DOI 10.1136/gutjnl-2014-306765, PubMed 24604824

Bretthauer M, Loberg M, Kalager M (2014)
Long-Term Colorectal-Cancer Mortality after Adenoma Removal REPLY
N. Engl. J. Med., 371 (21), 2035-2036

Bretthauer M, Løberg M, Kalager M (2014)
Long-term colorectal-cancer mortality after adenoma removal
N Engl J Med, 371 (21), 2036-7
DOI 10.1056/NEJMc1411954, PubMed 25409378

Garborg K, Kaminski MF, Lindenburger W, Wiig H, Hasund A, Wronska E, Bie RB, Kleist B, Løvdal L, Holme Ø, Kalager M, Hoff G, Bretthauer M (2014)
Water exchange versus carbon dioxide insufflation in unsedated colonoscopy: a multicenter randomized controlled trial
Endoscopy, 47 (3), 192-9
DOI 10.1055/s-0034-1390795, PubMed 25412093

Gjersvik P, Hem E, Jacobsen GW, Bretthauer M (2014)
[What should non-inferiority studies be called in Norwegian?]
Tidsskr Nor Laegeforen, 134 (8), 852-3
DOI 10.4045/tidsskr.14.0059, PubMed 24780988

Gjersvik P, Hem E, Jacobsen GW, Bretthauer M (2014)
[P. Gjersvik and colleagues reply]
Tidsskr Nor Laegeforen, 134 (12-13), 1215
DOI 10.4045/tidsskr.14.0744, PubMed 24989185

Hem E, Gjersvik P, Bretthauer M (2014)
[Comparative effectiveness research]
Tidsskr Nor Laegeforen, 134 (14), 1374
DOI 10.4045/tidsskr.14.0485, PubMed 25096435

Hoff G, Bretthauer M, Garborg K, Eide TJ (2014)
[Consensus-based guidelines may prevent necessary research]
Tidsskr Nor Laegeforen, 134 (2), 148-9
DOI 10.4045/tidsskr.13.1313, PubMed 24477144

Holme Ø, Bretthauer M, Eide TJ, Løberg EM, Grzyb K, Løberg M, Kalager M, Adami HO, Kjellevold Ø, Hoff G (2014)
Long-term risk of colorectal cancer in individuals with serrated polyps
Gut, 64 (6), 929-36
DOI 10.1136/gutjnl-2014-307793, PubMed 25399542

Holme Ø, Løberg M, Kalager M, Bretthauer M, Hernán MA, Aas E, Eide TJ, Skovlund E, Schneede J, Tveit KM, Hoff G (2014)
Effect of flexible sigmoidoscopy screening on colorectal cancer incidence and mortality: a randomized clinical trial
JAMA, 312 (6), 606-15
DOI 10.1001/jama.2014.8266, PubMed 25117129

Jodal HC, Reyes YD, Roksund G, Bretthauer M (2014)
[Implementation of guidelines for PSA testing in general practice]
Tidsskr Nor Laegeforen, 134 (21), 2032-4
DOI 10.4045/tidsskr.14.0982, PubMed 25387926

Kalager M, Adami HO, Bretthauer M (2014)
Too much mammography
BMJ, 348, g1403
DOI 10.1136/bmj.g1403, PubMed 24519765

Kalager M, Løberg M, Bretthauer M, Adami HO (2014)
Comparative analysis of breast cancer mortality following mammography screening in Denmark and Norway
Ann Oncol, 25 (6), 1137-43
DOI 10.1093/annonc/mdu122, PubMed 24669012

Leitao K, Grimstad T, Bretthauer M, Holme Ø, Paulsen V, Karlsen L, Isaksen K, Cvancarova M, Aabakken L (2014)
Polyethylene glycol vs sodium picosulfate/magnesium citrate for colonoscopy preparation
Endosc Int Open, 2 (4), E230-4
DOI 10.1055/s-0034-1377520, PubMed 26135098

Løberg M, Kalager M, Holme Ø, Hoff G, Adami HO, Bretthauer M (2014)
Long-term colorectal-cancer mortality after adenoma removal
N Engl J Med, 371 (9), 799-807
DOI 10.1056/NEJMoa1315870, PubMed 25162886

Spada C, Stoker J, Alarcon O, Barbaro F, Bellini D, Bretthauer M, De Haan MC, Dumonceau JM, Ferlitsch M, Halligan S, Helbren E, Hellstrom M, Kuipers EJ, Lefere P, Mang T, Neri E, Petruzziello L, Plumb A, Regge D, Taylor SA, Hassan C, Laghi A, European Society of Gastrointestinal Endoscopy, European Society of Gastrointestinal and Abdominal Radiology (2014)
Clinical indications for computed tomographic colonography: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline
Endoscopy, 46 (10), 897-915
DOI 10.1055/s-0034-1378092, PubMed 25268304

van Dam L, Bretthauer M (2014)
Ethical issues in colorectal cancer screening
Best Pract Res Clin Gastroenterol, 28 (2), 315-26
DOI 10.1016/j.bpg.2014.03.002, PubMed 24810192

Publications 2013

Bretthauer M, Holme Ø, Garborg K (2013)
Computed tomography colonography vs. colonoscopy for colorectal cancer screening: close call, but not closed case
Endoscopy, 45 (3), 159-60
DOI 10.1055/s-0032-1326208, PubMed 23446666

Bretthauer M, Kalager M (2013)
Principles, effectiveness and caveats in screening for cancer
Br J Surg, 100 (1), 55-65
DOI 10.1002/bjs.8995, PubMed 23212620

Fossmark R, Bretthauer M, Gustafsson BI (2013)
[Who should perform endoscopies?]
Tidsskr Nor Laegeforen, 133 (11), 1171
DOI 10.4045/tidsskr.13.0625, PubMed 23759774

Garborg K, Holme Ø, Løberg M, Kalager M, Adami HO, Bretthauer M (2013)
Current status of screening for colorectal cancer
Ann Oncol, 24 (8), 1963-72
DOI 10.1093/annonc/mdt157, PubMed 23619033

Hassan C, Bretthauer M, Kaminski MF, Polkowski M, Rembacken B, Saunders B, Benamouzig R, Holme O, Green S, Kuiper T, Marmo R, Omar M, Petruzziello L, Spada C, Zullo A, Dumonceau JM, European Society of Gastrointestinal Endoscopy (2013)
Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) guideline
Endoscopy, 45 (2), 142-50
DOI 10.1055/s-0032-1326186, PubMed 23335011

Hoff G, Bretthauer M, Garborg K, Eide TJ (2013)
New polyps, old tricks: controversy about removing benign bowel lesions
BMJ, 347, f5843
DOI 10.1136/bmj.f5843, PubMed 24103540

Holme O, Bretthauer M, de Lange T, Seip B, Huppertz-Hauss G, Høie O, Sandvei P, Ystrøm CM, Hoff G (2013)
Risk stratification to predict pain during unsedated colonoscopy: results of a multicenter cohort study
Endoscopy, 45 (9), 691-6
DOI 10.1055/s-0033-1344239, PubMed 23884794

Holme Ø, Bretthauer M, Fretheim A, Odgaard-Jensen J, Hoff G (2013)
Flexible sigmoidoscopy versus faecal occult blood testing for colorectal cancer screening in asymptomatic individuals
Cochrane Database Syst Rev, 2013 (9), CD009259
DOI 10.1002/14651858.CD009259.pub2, PubMed 24085634

Holme Ø, Moritz V, Bretthauer M, Seip B, Glomsaker T, de Lange T, Aabakken L, Stallemo A, Høie O, Dahler S, Sandvei PK, Stray N, Ystrøm CM, Hoff G (2013)
[Pain in connection with colonoscopy in Norway]
Tidsskr Nor Laegeforen, 133 (10), 1074-8
DOI 10.4045/tidsskr.12.1467, PubMed 23712171

Kalager M, Løberg M, Fønnebø VM, Bretthauer M (2013)
Failure to account for selection-bias
Int J Cancer, 133 (11), 2751-3
DOI 10.1002/ijc.28244, PubMed 23649899

Kuipers EJ, Rösch T, Bretthauer M (2013)
Colorectal cancer screening--optimizing current strategies and new directions
Nat Rev Clin Oncol, 10 (3), 130-42
DOI 10.1038/nrclinonc.2013.12, PubMed 23381005

Thiis-Evensen E, Kalager M, Bretthauer M, Hoff G (2013)
Long-term effectiveness of endoscopic screening on incidence and mortality of colorectal cancer: A randomized trial
United European Gastroenterol J, 1 (3), 162-8
DOI 10.1177/2050640613483290, PubMed 24917955

Vandvik PO, Bretthauer M, Kongerud IC (2013)
From clinical questions to trustworthy answers
Tidsskr Nor Laegeforen, 133 (15), 1611-4
DOI 10.4045/tidsskr.13.0650, PubMed 23970279

Publications 2012

Ahmed D, Danielsen SA, Aagesen TH, Bretthauer M, Thiis-Evensen E, Hoff G, Rognum TO, Nesbakken A, Lothe RA, Lind GE (2012)
A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors
Clin Transl Gastroenterol, 3 (12), e27
DOI 10.1038/ctg.2012.21, PubMed 23324654

Berstad P, Løberg M, Kalager M, Jørgensen A, Garborg K, Ruud HK, Bretthauer M, Hoff G (2012)
Risk stratification for advanced colorectal neoplasia--letter
Cancer Prev Res (Phila), 5 (12), 1405; author reply 1406
DOI 10.1158/1940-6207.CAPR-12-0383, PubMed 23151804

Bretthauer M, Hoff G (2012)
Comparative effectiveness research in cancer screening programmes
BMJ, 344, e2864
DOI 10.1136/bmj.e2864, PubMed 22628002

Bretthauer M, Kalager M (2012)
Colonoscopy as a triage screening test
N Engl J Med, 366 (8), 759-60
DOI 10.1056/NEJMe1114639, PubMed 22356330

Bretthauer M, Kalager M (2012)
Colorectal-Cancer Screening Reply
N. Engl. J. Med., 366 (22), 2131

European Colorectal Cancer Screening Guidelines Working Group, von Karsa L, Patnick J, Segnan N, Atkin W, Halloran S, Lansdorp-Vogelaar I, Malila N, Minozzi S, Moss S, Quirke P, Steele RJ, Vieth M, Aabakken L, Altenhofen L, Ancelle-Park R, Antoljak N, Anttila A, Armaroli P, Arrossi S, Austoker J, Banzi R, Bellisario C, Blom J, Brenner H et al. (2012)
European guidelines for quality assurance in colorectal cancer screening and diagnosis: overview and introduction to the full supplement publication
Endoscopy, 45 (1), 51-9
DOI 10.1055/s-0032-1325997, PubMed 23212726

Garborg K, Bretthauer M (2012)
Can old dogs learn new tricks?
J Interv Gastroenterol, 2 (3), 126-127
DOI 10.4161/jig.23733, PubMed 23805392

Garborg KK, Løberg M, Matre J, Holme O, Kalager M, Hoff G, Bretthauer M (2012)
Reduced pain during screening colonoscopy with an ultrathin colonoscope: a randomized controlled trial
Endoscopy, 44 (8), 740-6
DOI 10.1055/s-0032-1309755, PubMed 22622786

Hoff G, Moritz V, Bretthauer M, Aabakken L, Berset IP, Glomsaker T, Høie O, de Lange T (2012)
Incontinence after colonoscopy--an unrecognized and preventable problem. A cross-sectional study from the Gastronet quality assurance program
Endoscopy, 44 (4), 349-53
DOI 10.1055/s-0031-1291657, PubMed 22392101

Kalager M, Adami HO, Bretthauer M, Tamimi RM (2012)
Overdiagnosis of invasive breast cancer due to mammography screening: results from the Norwegian screening program
Ann Intern Med, 156 (7), 491-9
DOI 10.7326/0003-4819-156-7-201204030-00005, PubMed 22473436

Kalager M, Adami HO, Bretthauer M, Tamimi RM (2012)
Overdiagnosis of Invasive Breast Cancer due to Mammography Screening RESPONSE
Ann. Intern. Med., 157 (3), 221-222
DOI 10.7326/0003-4819-157-3-201208070-00025

Kalager M, Løberg M, Bretthauer M (2012)
Limited use of nonprogram screening in Norway
Int J Cancer, 132 (7), 1723-4
DOI 10.1002/ijc.27807, PubMed 22933134

Kalager M, Tamimi RM, Bretthauer M, Adami HO (2012)
Prognosis in women with interval breast cancer: population based observational cohort study
BMJ, 345, e7536
DOI 10.1136/bmj.e7536, PubMed 23160783

Kaminski MF, Bretthauer M, Zauber AG, Kuipers EJ, Adami HO, van Ballegooijen M, Regula J, van Leerdam M, Stefansson T, Påhlman L, Dekker E, Hernán MA, Garborg K, Hoff G (2012)
The NordICC Study: rationale and design of a randomized trial on colonoscopy screening for colorectal cancer
Endoscopy, 44 (7), 695-702
DOI 10.1055/s-0032-1306895, PubMed 22723185

Lenz P, Domagk D, Mensink P, Aktas H, Bretthauer M (2012)
Single- versus double-balloon enteroscopy: the evidence base: Comment on Endoscopy essentials, Small-bowel endoscopy
Endoscopy, 44 (8), 799; author reply 800
DOI 10.1055/s-0032-1310001, PubMed 22833025

Moritz V, Bretthauer M, Ruud HK, Glomsaker T, de Lange T, Sandvei P, Huppertz-Hauss G, Kjellevold Ø, Hoff G (2012)
Withdrawal time as a quality indicator for colonoscopy - a nationwide analysis
Endoscopy, 44 (5), 476-81
DOI 10.1055/s-0032-1306898, PubMed 22531983

Valori R, Rey JF, Atkin WS, Bretthauer M, Senore C, Hoff G, Kuipers EJ, Altenhofen L, Lambert R, Minoli G, International Agency for Research on Cancer (2012)
European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition--Quality assurance in endoscopy in colorectal cancer screening and diagnosis
Endoscopy, 44 Suppl 3, SE88-105
DOI 10.1055/s-0032-1309795, PubMed 23012124

Publications 2011

Bretthauer M (2011)
Colorectal cancer screening
J Intern Med, 270 (2), 87-98
DOI 10.1111/j.1365-2796.2011.02399.x, PubMed 21575082

Bretthauer M, Haug C (2011)
[What is established treatment?]
Tidsskr Nor Laegeforen, 131 (13-14), 1275
DOI 10.4045/tidsskr.11.13E1, PubMed 21725376

Cotton PB, Bretthauer M (2011)
Quality assurance in gastroenterology
Best Pract Res Clin Gastroenterol, 25 (3), 335-6
DOI 10.1016/j.bpg.2011.05.008, PubMed 21764001

de Vogel S, Schneede J, Ueland PM, Vollset SE, Meyer K, Fredriksen A, Midttun Ø, Bjørge T, Kampman E, Bretthauer M, Hoff G (2011)
Biomarkers related to one-carbon metabolism as potential risk factors for distal colorectal adenomas
Cancer Epidemiol Biomarkers Prev, 20 (8), 1726-35
DOI 10.1158/1055-9965.EPI-11-0359, PubMed 21693628

Domagk D, Mensink P, Aktas H, Lenz P, Meister T, Luegering A, Ullerich H, Aabakken L, Heinecke A, Domschke W, Kuipers E, Bretthauer M (2011)
Single- vs. double-balloon enteroscopy in small-bowel diagnostics: a randomized multicenter trial
Endoscopy, 43 (6), 472-6
DOI 10.1055/s-0030-1256247, PubMed 21384320

Hoff G, Volker M, Bretthauer M, Aabakken L, Høie O, Delange T, Berset I, Kjellevold Ø, Glomsaker T, Huppertz-Hauss G, Lange O, Sandvei P (2011)
Gastronet survey on the use of one- or two-person technique for colonoscopy insertion
BMC Gastroenterol, 11, 73
DOI 10.1186/1471-230X-11-73, PubMed 21672243

Holme Ö, Höie O, Matre J, Stallemo A, Garborg K, Hasund A, Wiig H, Hoff G, Bretthauer M (2011)
Magnetic endoscopic imaging versus standard colonoscopy in a routine colonoscopy setting: a randomized, controlled trial
Gastrointest Endosc, 73 (6), 1215-22
DOI 10.1016/j.gie.2011.01.054, PubMed 21481862

Lind GE, Danielsen SA, Ahlquist T, Merok MA, Andresen K, Skotheim RI, Hektoen M, Rognum TO, Meling GI, Hoff G, Bretthauer M, Thiis-Evensen E, Nesbakken A, Lothe RA (2011)
Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
Mol Cancer, 10, 85
DOI 10.1186/1476-4598-10-85, PubMed 21777459

Løberg M, Furholm S, Hoff I, Aabakken L, Hoff G, Bretthauer M (2011)
Nitrous oxide for analgesia in colonoscopy without sedation
Gastrointest Endosc, 74 (6), 1347-53
DOI 10.1016/j.gie.2011.07.071, PubMed 22136779

Publications 2010

Bretthauer M (2010)
Which tool is best for colorectal cancer screening?
BMJ, 340, c2831
DOI 10.1136/bmj.c2831, PubMed 20516015

Bretthauer M (2010)
["Shall I not be randomized?"]
Tidsskr Nor Laegeforen, 130 (11), 1119
DOI 10.4045/tidsskr.10.0590, PubMed 20531489

Bretthauer M (2010)
Evidence for colorectal cancer screening
Best Pract Res Clin Gastroenterol, 24 (4), 417-25
DOI 10.1016/j.bpg.2010.06.005, PubMed 20833346

Bretthauer M (2010)
Turning science into clinical practice - the case of carbon dioxide insufflation
Endoscopy, 42 (12), 1104-5
DOI 10.1055/s-0030-1255973, PubMed 21120777

Bretthauer M (2010)
Colorectal cancer screening Author's reply
Br. Med. J., 341, c4620
DOI 10.1136/bmj.c4620

Hoff G, Bretthauer M (2010)
[Colorectal cancer screening--at last discussed!]
Tidsskr Nor Laegeforen, 130 (20), 2012
DOI 10.4045/tidsskr.10.0932, PubMed 20967034

Hoff G, Moritz V, Bretthauer M, Ludolph T, Huppertz-Hauss G, Paulsen J, Seip B, Sauar J, Kjellevold Ø, Chengarov L (2010)
Colonoscope with a sub-distal hyper-flaccid segment for improved insertion at colonoscopy: a randomized study
Scand J Gastroenterol, 46 (1), 104-8
DOI 10.3109/00365521.2010.521891, PubMed 20923378

Seip B, Bretthauer M, Dahler S, Friestad J, Huppertz-Hauss G, Høie O, Kittang E, Nyhus S, Pallenschat J, Sandvei P, Stallemo A, Svendsen MV, Hoff G (2010)
Sustaining the vitality of colonoscopy quality improvement programmes over time. Experience from the Norwegian Gastronet programme
Scand J Gastroenterol, 45 (3), 362-9
DOI 10.3109/00365520903497106, PubMed 20095874

Seip B, Bretthauer M, Dahler S, Friestad J, Huppertz-Hauss G, Høie O, Kittang E, Nyhus S, Pallenschat J, Sandvei P, Stallemo A, Svendsen MV, Hoff G (2010)
Patient satisfaction with on-demand sedation for outpatient colonoscopy
Endoscopy, 42 (8), 639-46
DOI 10.1055/s-0030-1255612, PubMed 20669075

Publications 2009

Bretthauer M (2009)
The capsule and colorectal-cancer screening--the crux of the matter
N Engl J Med, 361 (3), 300-1
DOI 10.1056/NEJMe0903924, PubMed 19605836

Bretthauer M (2009)
The First Transatlantic Symposium on Colorectal Cancer Screening
Endoscopy, 41 (9), 816-7
DOI 10.1055/s-0029-1215049, PubMed 19685421

Bretthauer M (2009)
[A year with New England Journal of Medicine]
Tidsskr Nor Laegeforen, 129 (19), 1971
DOI 10.4045/tidsskr.09.1022, PubMed 19823197

Bretthauer M (2009)
[Do you understand me?]
Tidsskr Nor Laegeforen, 129 (21), 2211
DOI 10.4045/tidsskr.09.1081, PubMed 19898565

Bretthauer M (2009)
Capsule Endoscopy versus Colonoscopy REPLY
N. Engl. J. Med., 361 (16), 1609-1610

Bretthauer M, Haug C (2009)
[Without registration, no publishing!]
Tidsskr Nor Laegeforen, 129 (8), 733
DOI 10.4045/tidsskr.09.08E1, PubMed 19373295

Hoff G, Grotmol T, Skovlund E, Bretthauer M, Norwegian Colorectal Cancer Prevention Study Group (2009)
Risk of colorectal cancer seven years after flexible sigmoidoscopy screening: randomised controlled trial
BMJ, 338, b1846
DOI 10.1136/bmj.b1846, PubMed 19483252

Hoff G, Ottestad PM, Skafløtten SR, Bretthauer M, Moritz V (2009)
Quality assurance as an integrated part of the electronic medical record - a prototype applied for colonoscopy
Scand J Gastroenterol, 44 (10), 1259-65
DOI 10.1080/00365520903132021, PubMed 19658021

Kalager M, Bretthauer M (2009)
Spontaneous regression of invasive breast cancer: does this study answer the question?
Arch Intern Med, 169 (10), 997
DOI 10.1001/archinternmed.2009.91, PubMed 19468097

Kalager M, Haldorsen T, Bretthauer M, Hoff G, Thoresen SO, Adami HO (2009)
Improved breast cancer survival following introduction of an organized mammography screening program among both screened and unscreened women: a population-based cohort study
Breast Cancer Res, 11 (4), R44
DOI 10.1186/bcr2331, PubMed 19575807

Publications 2008

Bretthauer M (2008)
[Statistical significance and clinical relevance]
Tidsskr Nor Laegeforen, 128 (3), 279
PubMed 18264146

Bretthauer M (2008)
Are sodium phosphate tablets better than polyethylene glycol solution plus bisacodyl tablets for bowel preparation?
Nat Clin Pract Gastroenterol Hepatol, 5 (6), 296-7
DOI 10.1038/ncpgasthep1142, PubMed 18461058

Bretthauer M (2008)
Erroneous on screening colonoscopy
Z. Gastroent., 46 (6), 633

Hoff G, Bretthauer M (2008)
Appointments timed in proximity to annual milestones and compliance with screening: randomised controlled trial
BMJ, 337, a2794
DOI 10.1136/bmj.a2794, PubMed 19091759

Seip B, Huppertz-Hauss G, Sauar J, Bretthauer M, Hoff G (2008)
Patients' satisfaction: an important factor in quality control of gastroscopies
Scand J Gastroenterol, 43 (8), 1004-11
DOI 10.1080/00365520801958592, PubMed 19086282

Publications 2007

Bretthauer M, Hoff G (2007)
[Prevention and early diagnosis of colorectal cancer]
Tidsskr Nor Laegeforen, 127 (20), 2688-91
PubMed 17952153

Bretthauer M, Seip B, Aasen S, Kordal M, Hoff G, Aabakken L (2007)
Carbon dioxide insufflation for more comfortable endoscopic retrograde cholangiopancreatography: a randomized, controlled, double-blind trial
Endoscopy, 39 (1), 58-64
DOI 10.1055/s-2006-945036, PubMed 17252462

Domagk D, Bretthauer M, Lenz P, Aabakken L, Ullerich H, Maaser C, Domschke W, Kucharzik T (2007)
Carbon dioxide insufflation improves intubation depth in double-balloon enteroscopy: a randomized, controlled, double-blind trial
Endoscopy, 39 (12), 1064-7
DOI 10.1055/s-2007-966990, PubMed 18072057

Hoff G, Bretthauer M (2007)
Colonic explosion: an unavoidable complication?
Endoscopy, 39 (3), 258
DOI 10.1055/s-2007-966200, PubMed 17385113

Hoff G, Bretthauer M, Dahler S, Huppertz-Hauss G, Sauar J, Paulsen J, Seip B, Moritz V (2007)
Improvement in caecal intubation rate and pain reduction by using 3-dimensional magnetic imaging for unsedated colonoscopy: a randomized trial of patients referred for colonoscopy
Scand J Gastroenterol, 42 (7), 885-9
DOI 10.1080/00365520601127125, PubMed 17558914

Skovlund E, Bretthauer M (2007)
Kliniske studier
In Epidemiologiske og kliniske forskningsmetoder, Gyldendal akademisk, Oslo, [285]-[301]
BIBSYS 071649743

Søreide K, Bretthauer M (2007)
[Colorectal cancer--a disease one doesn't talk about]
Tidsskr Nor Laegeforen, 127 (20), 2651
PubMed 17952144

Aabakken L, Bretthauer M, Line PD (2007)
Double-balloon enteroscopy for endoscopic retrograde cholangiography in patients with a Roux-en-Y anastomosis
Endoscopy, 39 (12), 1068-71
DOI 10.1055/s-2007-966841, PubMed 18072058

Publications 2006

Bretthauer M (2006)
[Can CT colonography replace coloscopy?]
Tidsskr Nor Laegeforen, 126 (11), 1464
PubMed 16732337

Bretthauer M, Ekbom A, Malila N, Stefánsson T, Fischer A, Hof G, Weiderpass E, Tretli S, Tryggvadóttir L, Storm H, Holten I, Adam HO (2006)
[Screening for colorectal cancer. Collaboration among politicians and scientists is necessary]
Laeknabladid, 92 (7-8), 521-4
PubMed 16818999

Bretthauer M, Ekbom A, Malila N, Stefansson T, Fischer A, Hoff G, Weiderpass E, Tretli S, Trygvadottir L, Holten IW, Storm HH, Adami HO (2006)
[Politics and science in colorectal cancer screening]
Ugeskr Laeger, 168 (26-32), 2563-5
PubMed 16824412

Bretthauer M, Ekbom A, Malila N, Stefansson T, Fischer A, Hoff G, Weiderpass E, Tretli S, Trygvadottir L, Storm H, Holten I, Adami HO, NordICC-gruppen (Nordic Initiative on Colorectal Cancer) (2006)
[Politics and science in colorectal cancer screening]
Tidsskr Nor Laegeforen, 126 (13), 1766-7
PubMed 16794676

Hoff G, Bretthauer M (2006)
The science and politics of colorectal cancer screening
PLoS Med, 3 (1), e36; quiz e104
DOI 10.1371/journal.pmed.0030036, PubMed 16383349

Hoff G, Bretthauer M, Huppertz-Hauss G, Kittang E, Stallemo A, Høie O, Dahler S, Nyhus S, Halvorsen FA, Pallenschat J, Vetvik K, Kristian Sandvei P, Friestad J, Pytte R, Coll P (2006)
The Norwegian Gastronet project: Continuous quality improvement of colonoscopy in 14 Norwegian centres
Scand J Gastroenterol, 41 (4), 481-7
DOI 10.1080/00365520500265208, PubMed 16635918

Publications 2005

Bretthauer M, Hoff G (2005)
[Quality improvement in Norwegian hospitals]
Tidsskr Nor Laegeforen, 125 (9), 1150
PubMed 15880147

Bretthauer M, Lynge AB, Thiis-Evensen E, Hoff G, Fausa O, Aabakken L (2005)
Carbon dioxide insufflation in colonoscopy: safe and effective in sedated patients
Endoscopy, 37 (8), 706-9
DOI 10.1055/s-2005-870154, PubMed 16032487

Gondal G, Grotmol T, Hofstad B, Bretthauer M, Eide TJ, Hoff G (2005)
Lifestyle-related risk factors and chemoprevention for colorectal neoplasia: experience from the large-scale NORCCAP screening trial
Eur J Cancer Prev, 14 (4), 373-9
DOI 10.1097/00008469-200508000-00010, PubMed 16030428

Gondal G, Grotmol T, Hofstad B, Bretthauer M, Eide TJ, Hoff G (2005)
Biopsy of colorectal polyps is not adequate for grading of neoplasia
Endoscopy, 37 (12), 1193-7
DOI 10.1055/s-2005-921031, PubMed 16329016

Hoff G, Bretthauer M, Huppertz-Hauss G, Sauar J, Paulsen J, Dahler S, Kjellevold Ø (2005)
Evaluation of a novel colonoscope designed for easier passage through flexures: a randomized study
Endoscopy, 37 (11), 1123-6
DOI 10.1055/s-2005-870444, PubMed 16281143

Huppertz-Hauss G, Bretthauer M, Sauar J, Paulsen J, Kjellevold Ø, Majak B, Hoff G (2005)
Polyethylene glycol versus sodium phosphate in bowel cleansing for colonoscopy: a randomized trial
Endoscopy, 37 (6), 537-41
DOI 10.1055/s-2005-861315, PubMed 15933926

Skovlund E, Bretthauer M, Grotmol T, Larsen IK, Hoff G (2005)
Sensitivity of pain rating scales in an endoscopy trial
Clin J Pain, 21 (4), 292-6
DOI 10.1097/01.ajp.0000110636.14355.3e, PubMed 15951645

Aamodt G, Gulbrandsen P, Laake P, Aavitsland P, Bretthauer M (2005)
[Presentation of statistical analysis in the Journal of the Norwegian Medical Association]
Tidsskr Nor Laegeforen, 125 (16), 2183-7
PubMed 16138131

Publications 2004

Bretthauer M (2004)
[Information about mammography screening]
Tidsskr Nor Laegeforen, 124 (17), 2227
PubMed 15356683

Bretthauer M (2004)
[When can generic preparations be used?]
Tidsskr Nor Laegeforen, 124 (20), 2598
PubMed 15534628

Bretthauer M (2004)
Colorectal cancer screening by flexible sigmoidoscopy: aspects of quality control and quality improvement based on experience from the NORCCAP (Norwegian Colorectal Cancer Prevention) trial
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 146, 1 b. (flere pag.)
BIBSYS 040132331, ISBN 82-8072-079-0

Bretthauer M, Hoff G, Severinsen H, Erga J, Sauar J, Huppertz-Hauss G (2004)
[Systematic quality control programme for colonoscopy in an endoscopy centre in Norway]
Tidsskr Nor Laegeforen, 124 (10), 1402-5
PubMed 15195182

Hoff G, Grotmol T, Thiis-Evensen E, Bretthauer M, Gondal G, Vatn MH (2004)
Testing for faecal calprotectin (PhiCal) in the Norwegian Colorectal Cancer Prevention trial on flexible sigmoidoscopy screening: comparison with an immunochemical test for occult blood (FlexSure OBT)
Gut, 53 (9), 1329-33
DOI 10.1136/gut.2004.039032, PubMed 15306594

Publications 2003

Bretthauer M, Hoff G (2003)
The use of CO2 in colonoscopy
Gastrointest Endosc, 57 (3), 436-7; author reply 437-8
DOI 10.1067/mge.2003.108, PubMed 12612542

Bretthauer M, Hoff GS, Thiis-Evensen E, Huppertz-Hauss G, Skovlund E (2003)
Air and carbon dioxide volumes insufflated during colonoscopy
Gastrointest Endosc, 58 (2), 203-6
DOI 10.1067/mge.2003.340, PubMed 12872086

Bretthauer M, Jørgensen A, Kristiansen BE, Hofstad B, Hoff G (2003)
Quality control in colorectal cancer screening: systematic microbiological investigation of endoscopes used in the NORCCAP (Norwegian Colorectal Cancer Prevention) trial
BMC Gastroenterol, 3, 15
DOI 10.1186/1471-230X-3-15, PubMed 12803654

Bretthauer M, Skovlund E, Grotmol T, Thiis-Evensen E, Gondal G, Huppertz-Hauss G, Efskind P, Hofstad B, Thorp Holmsen S, Eide TJ, Hoff G (2003)
Inter-endoscopist variation in polyp and neoplasia pick-up rates in flexible sigmoidoscopy screening for colorectal cancer
Scand J Gastroenterol, 38 (12), 1268-74
DOI 10.1080/00365520310006513, PubMed 14750648

Gondal G, Grotmol T, Hofstad B, Bretthauer M, Eide TJ, Hoff G (2003)
Grading of distal colorectal adenomas as predictors for proximal colonic neoplasia and choice of endoscope in population screening: experience from the Norwegian Colorectal Cancer Prevention study (NORCCAP)
Gut, 52 (3), 398-403
DOI 10.1136/gut.52.3.398, PubMed 12584223

Gondal G, Grotmol T, Hofstad B, Bretthauer M, Eide TJ, Hoff G (2003)
The Norwegian Colorectal Cancer Prevention (NORCCAP) screening study: baseline findings and implementations for clinical work-up in age groups 50-64 years
Scand J Gastroenterol, 38 (6), 635-42
DOI 10.1080/00365520310003002, PubMed 12825872

Hoff G, Bretthauer M, Skovlund E, Grotmol T (2003)
Re: Baseline findings of the Italian multicenter randomized controlled trial of "once-only sigmoidoscopy"--SCORE
J Natl Cancer Inst, 95 (14), 1089-90; author reply 1090
DOI 10.1093/jnci/95.14.1089, PubMed 12865459

Publications 2002

Bretthauer M, Gondal G, Larsen K, Carlsen E, Eide TJ, Grotmol T, Skovlund E, Tveit KM, Vatn MH, Hoff G (2002)
Design, organization and management of a controlled population screening study for detection of colorectal neoplasia: attendance rates in the NORCCAP study (Norwegian Colorectal Cancer Prevention)
Scand J Gastroenterol, 37 (5), 568-73
DOI 10.1080/00365520252903125, PubMed 12059059

Bretthauer M, Hoff G, Thiis-Evensen E, Grotmol T, Holmsen ST, Moritz V, Skovlund E (2002)
Carbon dioxide insufflation reduces discomfort due to flexible sigmoidoscopy in colorectal cancer screening
Scand J Gastroenterol, 37 (9), 1103-7
DOI 10.1080/003655202320378329, PubMed 12374237

Bretthauer M, Hoff G, Thiis-Evensen E, Grotmol T, Larsen IK, Kjellevold Ø, Skovlund E (2002)
Use of a disposable sheath system for flexible sigmoidoscopy in decentralized colorectal cancer screening
Endoscopy, 34 (10), 814-8
DOI 10.1055/s-2002-34273, PubMed 12244504

Bretthauer M, Thiis-Evensen E, Huppertz-Hauss G, Gisselsson L, Grotmol T, Skovlund E, Hoff G (2002)
NORCCAP (Norwegian colorectal cancer prevention): a randomised trial to assess the safety and efficacy of carbon dioxide versus air insufflation in colonoscopy
Gut, 50 (5), 604-7
DOI 10.1136/gut.50.5.604, PubMed 11950803

Larsen IK, Grotmol T, Bretthauer M, Gondal G, Huppertz-Hauss G, Hofstad B, Efskind P, Jørgensen A, Hoff G (2002)
Continuous evaluation of patient satisfaction in endoscopy centres
Scand J Gastroenterol, 37 (7), 850-5
DOI 10.1080/713786520, PubMed 12190102

Publications 2000

Bretthauer M, Kalager M (2000)
[Practice from Germany not sanctioned as specialist education in Norway]
Tidsskr Nor Laegeforen, 120 (21), 2580-1
PubMed 11071005

Publications 1996

Panzer W, Bretthauer M, Klingler H, Bahr J, Rathgeber J, Kettler D (1996)
ACD versus standard CPR in a prehospital setting
Resuscitation, 33 (2), 117-24
DOI 10.1016/s0300-9572(96)01021-0, PubMed 9025127