Divison of Cancer Medicine Last 100 publications from major journals with first or last author from OUS
Co-occurring mutations identify prognostic subgroups of microsatellite stable colorectal cancer
Mol Cancer, 23 (1), 264
DOI 10.1186/s12943-024-02173-x, PubMed 39587554
Immunological facets of prostate cancer and the potential of immune checkpoint inhibition in disease management
Theranostics, 14 (18), 6913-6934
DOI 10.7150/thno.100555, PubMed 39629128
Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor
Med (in press)
DOI 10.1016/j.medj.2024.09.010, PubMed 39423821
Targeting IRE1α reprograms the tumor microenvironment and enhances anti-tumor immunity in prostate cancer
Nat Commun, 15 (1), 8895
DOI 10.1038/s41467-024-53039-1, PubMed 39406723
Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones
Nat Commun, 15 (1), 8579
DOI 10.1038/s41467-024-52980-5, PubMed 39362905
Pitfalls in lipid mass spectrometry of mammalian samples - a brief guide for biologists
Nat Rev Mol Cell Biol, 25 (10), 759-760
DOI 10.1038/s41580-024-00758-4, PubMed 38951702
PI3K Inhibitors in Hematology: When One Door Closes…
Clin Cancer Res, 30 (17), 3667-3675
DOI 10.1158/1078-0432.CCR-24-0967, PubMed 38967552
Exosome regulation by Rubicon in ageing
Nat Cell Biol, 26 (9), 1380-1381
DOI 10.1038/s41556-024-01482-z, PubMed 39174741
Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma
Blood Cancer J, 14 (1), 147
DOI 10.1038/s41408-024-01124-5, PubMed 39191762
Outcome prediction based on [18F]FDG PET/CT in patients with pleural mesothelioma treated with ipilimumab and nivolumab +/- UV1 telomerase vaccine
Eur J Nucl Med Mol Imaging (in press)
DOI 10.1007/s00259-024-06853-0, PubMed 39133306
Prognostic genome and transcriptome signatures in colorectal cancers
Nature, 633 (8028), 137-146
DOI 10.1038/s41586-024-07769-3, PubMed 39112715
From sweat to hope: The role of exercise-induced extracellular vesicles in cancer prevention and treatment
J Extracell Vesicles, 13 (8), e12500
DOI 10.1002/jev2.12500, PubMed 39183543
Author Correction: IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
Nat Commun, 15 (1), 6190
DOI 10.1038/s41467-024-50645-x, PubMed 39043728
Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
Cell Stem Cell, 31 (9), 1376-1386.e8
DOI 10.1016/j.stem.2024.06.011, PubMed 38981470
Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping
Nat Immunol, 25 (8), 1445-1459
DOI 10.1038/s41590-024-01884-z, PubMed 38956379
Health-related quality of life in relapsed/refractory multiple myeloma treated with melflufen and dexamethasone: analyses from the phase III OCEAN study
Haematologica, 109 (7), 2331-2336
DOI 10.3324/haematol.2023.284635, PubMed 38426292
Egr2 to the rescue: nanoparticles revitalize natural killer cells in the fight against cancer
EMBO J, 43 (13), 2527-2529
DOI 10.1038/s44318-024-00144-y, PubMed 38886578
B7-H3: a robust target for immunotherapy in prostate cancer
Trends Cancer, 10 (7), 584-587
DOI 10.1016/j.trecan.2024.05.003, PubMed 38839545
Multiregional transcriptomics identifies congruent consensus subtypes with prognostic value beyond tumor heterogeneity of colorectal cancer
Nat Commun, 15 (1), 4342
DOI 10.1038/s41467-024-48706-2, PubMed 38773143
CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
Cell Rep Med, 5 (6), 101572
DOI 10.1016/j.xcrm.2024.101572, PubMed 38754420
Overall survival and causes of death in elderly patients with Hodgkin lymphoma: a Norwegian population-based case-control study
Haematologica, 109 (5), 1403-1412
DOI 10.3324/haematol.2023.283721, PubMed 37881879
Engineering immune-evasive allogeneic cellular immunotherapies
Nat Rev Immunol, 24 (9), 680-693
DOI 10.1038/s41577-024-01022-8, PubMed 38658708
In multiple myeloma, monthly treatment with zoledronic acid beyond two years offers sustained protection against progressive bone disease
Blood Cancer J, 14 (1), 65
DOI 10.1038/s41408-024-01046-2, PubMed 38622134
Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16
J Immunother Cancer, 12 (4)
DOI 10.1136/jitc-2023-008179, PubMed 38604812
VRD versus VCD as induction therapy before autologous stem cell transplantation in multiple myeloma: a nationwide population-based study
Blood Cancer J, 14 (1), 60
DOI 10.1038/s41408-024-01047-1, PubMed 38594252
Transient TCR-based T cell therapy in a patient with advanced treatment-resistant MSI-high colorectal cancer
Mol Ther, 32 (6), 2021-2029
DOI 10.1016/j.ymthe.2024.04.009, PubMed 38582964
Incidence and Factors Associated With Second Primary Invasive Melanoma in Norway
JAMA Dermatol, 160 (4), 402-408
DOI 10.1001/jamadermatol.2023.6251, PubMed 38416466
Quality of life endpoints in cancer cachexia clinical trials: Systematic review 3 of the cachexia endpoints series
J Cachexia Sarcopenia Muscle, 15 (3), 794-815
DOI 10.1002/jcsm.13453, PubMed 38553255
A dual-purpose fusion complex in autophagy
Cell Res, 34 (3), 183-184
DOI 10.1038/s41422-023-00925-w, PubMed 38228880
Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study
Nat Commun, 15 (1), 1791
DOI 10.1038/s41467-024-46033-0, PubMed 38424056
Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
Nat Commun, 15 (1), 1277
DOI 10.1038/s41467-024-45558-8, PubMed 38341434
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature
Biochim Biophys Acta Rev Cancer, 1879 (2), 189080
DOI 10.1016/j.bbcan.2024.189080, PubMed 38272101
Ipilimumab and nivolumab combined with anthracycline-based chemotherapy in metastatic hormone receptor-positive breast cancer: a randomized phase 2b trial
J Immunother Cancer, 12 (1)
DOI 10.1136/jitc-2023-007990, PubMed 38242720
Lysophagy prevents neurotoxic aggregate transmission
Proc Natl Acad Sci U S A, 121 (3), e2321181121
DOI 10.1073/pnas.2321181121, PubMed 38190545
Sudarshan Kriya Yoga Breathing and a Meditation Program for Burnout Among Physicians: A Randomized Clinical Trial
JAMA Netw Open, 7 (1), e2353978
DOI 10.1001/jamanetworkopen.2023.53978, PubMed 38294813
ATPase-regulated autophagosome biogenesis
Autophagy, 20 (1), 218-219
DOI 10.1080/15548627.2023.2255967, PubMed 37722386
Robust scoring of selective drug responses for patient-tailored therapy selection
Nat Protoc, 19 (1), 60-82
DOI 10.1038/s41596-023-00903-x, PubMed 37996540
Removal of hypersignaling endosomes by simaphagy
Autophagy, 20 (4), 769-791
DOI 10.1080/15548627.2023.2267958, PubMed 37840274
Adipose-Derived Stromal Cells Preserve Pancreatic Islet Function in a Transplantable 3D Bioprinted Scaffold
Adv Healthc Mater, 12 (32), e2300640
DOI 10.1002/adhm.202300640, PubMed 37781993
Transcriptomic subtyping of malignant peripheral nerve sheath tumours highlights immune signatures, genomic profiles, patient survival and therapeutic targets
EBioMedicine, 97, 104829
DOI 10.1016/j.ebiom.2023.104829, PubMed 37837931
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo
Nat Cancer, 4 (10), 1474-1490
DOI 10.1038/s43018-023-00642-8, PubMed 37783807
Mapping the chemotactic landscape in NK cells reveals subset-specific synergistic migratory responses to dual chemokine receptor ligation
EBioMedicine, 96, 104811
DOI 10.1016/j.ebiom.2023.104811, PubMed 37741009
Adverse health outcomes and global quality of life in long-term testicular cancer survivors: a longitudinal 30-year perspective
Ann Oncol, 34 (12), 1165-1174
DOI 10.1016/j.annonc.2023.09.3101, PubMed 37739265
The separate axes of TECPR1 and ATG16L1 in CASM
Autophagy, 20 (1), 214-215
DOI 10.1080/15548627.2023.2255462, PubMed 37676042
The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy
Haematologica, 108 (9), 2454-2466
DOI 10.3324/haematol.2022.282289, PubMed 36861406
Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial
Clin Cancer Res, 29 (16), 3026-3036
DOI 10.1158/1078-0432.CCR-23-0416, PubMed 37378632
Intensifying treatment in PET-positive multiple myeloma patients after upfront autologous stem cell transplantation
Leukemia, 37 (10), 2107-2114
DOI 10.1038/s41375-023-01998-7, PubMed 37568010
A phosphoinositide kinase triggers migrasome formation
Cell Res, 33 (8), 577-578
DOI 10.1038/s41422-023-00822-2, PubMed 37165066
WT1 and PRAME RNA-loaded dendritic cell vaccine as maintenance therapy in de novo AML after intensive induction chemotherapy
Leukemia, 37 (9), 1842-1849
DOI 10.1038/s41375-023-01980-3, PubMed 37507426
ATPase activity of DFCP1 controls selective autophagy
Nat Commun, 14 (1), 4051
DOI 10.1038/s41467-023-39641-9, PubMed 37422481
TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
EMBO J, 42 (17), e113105
DOI 10.15252/embj.2022113105, PubMed 37409525
ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma
Nat Commun, 14 (1), 3375
DOI 10.1038/s41467-023-39097-x, PubMed 37291203
Improved survival in myeloma patients-a nationwide registry study of 4,647 patients ≥75 years treated in Denmark and Sweden
Haematologica, 108 (6), 1640-1651
DOI 10.3324/haematol.2021.280424, PubMed 36300775
The Effects of Exercise Training in Patients With Persistent Dyspnea Following Pulmonary Embolism: A Randomized Controlled Trial
Chest, 164 (4), 981-991
DOI 10.1016/j.chest.2023.04.042, PubMed 37149257
Reply to the Letter to the Editor "A simple way of doing the complex but utmost important things: cancer pain management" by S. Singhal, M. Verma and D. Kukreja
Ann Oncol, 34 (5), 496-497
DOI 10.1016/j.annonc.2023.02.005, PubMed 37121609
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database
EClinicalMedicine, 58, 101909
DOI 10.1016/j.eclinm.2023.101909, PubMed 37181409
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
J Allergy Clin Immunol, 152 (1), 278-289.e6
DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861
Author Correction: Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution
Nat Commun, 14 (1), 648
DOI 10.1038/s41467-023-36404-4, PubMed 36746973
Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse
Proc Natl Acad Sci U S A, 120 (6), e2211368120
DOI 10.1073/pnas.2211368120, PubMed 36730202
PI3K inhibitors in chronic lymphocytic leukemia: where do we go from here?
Haematologica, 108 (1), 9-21
DOI 10.3324/haematol.2022.281266, PubMed 35899388
T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases
Gigascience, 12
DOI 10.1093/gigascience/giad032, PubMed 37161965
Targeted Therapy on the Screen: Do We Hit the Target?
Clin Cancer Res, 28 (24), 5233-5234
DOI 10.1158/1078-0432.CCR-22-2707, PubMed 36240006
Regulation of autophagosome biogenesis and mitochondrial bioenergetics by the cholesterol transport protein GRAMD1C
Autophagy, 19 (7), 2159-2161
DOI 10.1080/15548627.2022.2155020, PubMed 36469687
Re: Spatially Resolved Clonal Copy Number Alterations in Benign and Malignant Tissue
Eur Urol, 83 (2), 183
DOI 10.1016/j.eururo.2022.11.013, PubMed 36464529
Atezolizumab plus anthracycline-based chemotherapy in metastatic triple-negative breast cancer: the randomized, double-blind phase 2b ALICE trial
Nat Med, 28 (12), 2573-2583
DOI 10.1038/s41591-022-02126-1, PubMed 36482103
Cis-regulatory mutations associate with transcriptional and post-transcriptional deregulation of gene regulatory programs in cancers
Nucleic Acids Res, 50 (21), 12131-12148
DOI 10.1093/nar/gkac1143, PubMed 36477895
Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
EMBO J, 41 (24), e112677
DOI 10.15252/embj.2022112677, PubMed 36408828
Total late effect burden in long-term lymphoma survivors after high-dose therapy with autologous stem-cell transplant and its effect on health-related quality of life
Haematologica, 107 (11), 2698-2707
DOI 10.3324/haematol.2021.280413, PubMed 35484681
The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
Nat Commun, 13 (1), 6283
DOI 10.1038/s41467-022-33933-2, PubMed 36270994
Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Clin Cancer Res, 28 (20), 4444-4455
DOI 10.1158/1078-0432.CCR-22-1221, PubMed 35998013
Estimated daily intake of phthalates, parabens, and bisphenol A in hospitalised very low birth weight infants
Chemosphere, 309 (Pt 1), 136687
DOI 10.1016/j.chemosphere.2022.136687, PubMed 36206919
Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
Trends Pharmacol Sci, 43 (11), 973-985
DOI 10.1016/j.tips.2022.08.009, PubMed 36163057
A novel, rapid and sensitive flow cytometry method reveals degradation of promoter proximal paused RNAPII in the presence and absence of UV
Nucleic Acids Res, 50 (15), e89
DOI 10.1093/nar/gkac434, PubMed 35641102
Determining drug dose in the era of targeted therapies: playing it (un)safe?
Blood Cancer J, 12 (8), 123
DOI 10.1038/s41408-022-00720-7, PubMed 35999205
A clinical decision support system optimising adjuvant chemotherapy for colorectal cancers by integrating deep learning and pathological staging markers: a development and validation study
Lancet Oncol, 23 (9), 1221-1232
DOI 10.1016/S1470-2045(22)00391-6, PubMed 35964620
An immunity and pyroptosis gene-pair signature predicts overall survival in acute myeloid leukemia
Leukemia, 36 (10), 2384-2395
DOI 10.1038/s41375-022-01662-6, PubMed 35945345
Functional testing of relapsed chronic lymphocytic leukemia guides precision medicine and maps response and resistance mechanisms. An index case
Haematologica, 107 (8), 1994-1998
DOI 10.3324/haematol.2021.280393, PubMed 35236056
An Experimental Generator for Production of High-Purity 212Pb for Use in Radiopharmaceuticals
J Nucl Med, 64 (1), 173-176
DOI 10.2967/jnumed.122.264009, PubMed 35798556
ESCRTed resistance to T cell attack
Trends Immunol, 43 (8), 598-600
DOI 10.1016/j.it.2022.06.007, PubMed 35810056
SynergyFinder 3.0: an interactive analysis and consensus interpretation of multi-drug synergies across multiple samples
Nucleic Acids Res, 50 (W1), W739-W743
DOI 10.1093/nar/gkac382, PubMed 35580060
Corrigendum to "Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft", [Journal of Control Release, 293 (2019) 183-192]
J Control Release, 349, 1
DOI 10.1016/j.jconrel.2022.06.040, PubMed 35792388
Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges
Adv Drug Deliv Rev, 186, 114326
DOI 10.1016/j.addr.2022.114326, PubMed 35588953
Autophagy power expands: fuse those cells!
EMBO J, 41 (12), e111424
DOI 10.15252/embj.2022111424, PubMed 35561082
Durable and dynamic hTERT immune responses following vaccination with the long-peptide cancer vaccine UV1: long-term follow-up of three phase I clinical trials
J Immunother Cancer, 10 (5)
DOI 10.1136/jitc-2021-004345, PubMed 35613827
A national precision cancer medicine implementation initiative for Norway
Nat Med, 28 (5), 885-887
DOI 10.1038/s41591-022-01777-4, PubMed 35513529
Mortality and Second Cancer Incidence After Treatment for Testicular Cancer: Psychosocial Health and Lifestyle Are Modifiable Prognostic Factors
J Clin Oncol, 40 (23), 2588-2599
DOI 10.1200/JCO.21.02105, PubMed 35380874
Melflufen in multiple myeloma: the conclusion matters - Authors' reply
Lancet Haematol, 9 (4), e244-e245
DOI 10.1016/S2352-3026(22)00071-0, PubMed 35358436
Need for more focus on lipid species in studies of biological and model membranes
Prog Lipid Res, 86, 101160
DOI 10.1016/j.plipres.2022.101160, PubMed 35288150
Fully-automated and ultra-fast cell-type identification using specific marker combinations from single-cell transcriptomic data
Nat Commun, 13 (1), 1246
DOI 10.1038/s41467-022-28803-w, PubMed 35273156
Isatuximab plus pomalidomide and dexamethasone in elderly patients with relapsed/refractory multiple myeloma: ICARIA-MM subgroup analysis
Haematologica, 107 (3), 774-775
DOI 10.3324/haematol.2021.279160, PubMed 35229573
Melflufen or pomalidomide plus dexamethasone for patients with multiple myeloma refractory to lenalidomide (OCEAN): a randomised, head-to-head, open-label, phase 3 study
Lancet Haematol, 9 (2), e98-e110
DOI 10.1016/S2352-3026(21)00381-1, PubMed 35032434
Re: Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer
Eur Urol, 81 (4), 431
DOI 10.1016/j.eururo.2021.12.031, PubMed 35031159
GAK and PRKCD kinases regulate basal mitophagy
Autophagy, 18 (2), 467-469
DOI 10.1080/15548627.2021.2015154, PubMed 35001811
Association of β-Blocker Use at Time of Radical Prostatectomy With Rate of Treatment for Prostate Cancer Recurrence
JAMA Netw Open, 5 (1), e2145230
DOI 10.1001/jamanetworkopen.2021.45230, PubMed 35080602
Multiplex immunohistochemistry of metastatic colorectal cancer and ex vivo tumor avatars
Biochim Biophys Acta Rev Cancer, 1877 (1), 188682
DOI 10.1016/j.bbcan.2022.188682, PubMed 35065193
Autophagy modulates cell fate decisions during lineage commitment
Autophagy, 18 (8), 1915-1931
DOI 10.1080/15548627.2021.2008691, PubMed 34923909
Sutimlimab, an investigational C1s inhibitor, effectively prevents exacerbation of hemolytic anemia in a patient with cold agglutinin disease undergoing major surgery
Am J Hematol, 97 (2), E51-E54
DOI 10.1002/ajh.26409, PubMed 34778998
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
Nat Biotechnol, 40 (4), 488-498
DOI 10.1038/s41587-021-01089-x, PubMed 34873326
Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
Hepatology, 75 (1), 59-73
DOI 10.1002/hep.32125, PubMed 34435693
Publisher Correction: Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production
Nat Commun, 12 (1), 7073
DOI 10.1038/s41467-021-27175-x, PubMed 34848706