Publications 2024

Gopalakrishnan RP, Østrøm MS, Skjeldal FM, Bakke O, Bogen B, Huszthy PC (2024)
B Cells With Complementary B Cell Receptors Can Kill Each Other
55 (1), e202350890
DOI 10.1002/eji.202350890, PubMed 39520365

Hinke DM, Anderson AM, Katta K, Laursen MF, Tesfaye DY, Werninghaus IC, Angeletti D, Grødeland G, Bogen B, Braathen R (2024)
Applying valency-based immuno-selection to generate broadly cross-reactive antibodies against influenza hemagglutinins
15 (1), 850
DOI 10.1038/s41467-024-44889-w, PubMed 38346952

Publications 2023

Jadhav SS, Luboshits G, Bogen B, Firer MA (2023)
Tracking the cellular immune response from early premalignancy to active multiple myeloma in a new model
54 (1), e2350627
DOI 10.1002/eji.202350627, PubMed 37872778

Kikuchi J, Kodama N, Takeshita M, Ikeda S, Kobayashi T, Kuroda Y, Uchiyama M, Osada N, Bogen B, Yasui H, Takahashi N, Miwa A, Furukawa Y (2023)
EMD originates from hyaluronan-induced homophilic interactions of CD44 variant-expressing MM cells under shear stress
7 (4), 508-524
DOI 10.1182/bloodadvances.2022007291, PubMed 35930695

Métivier C, Le Saëc P, Gaschet J, Chauvet C, Marionneau-Lambot S, Hofgaard PO, Bogen B, Pineau J, Le Bris N, Tripier R, Alliot C, Haddad F, Chérel M, Chouin N, Faivre-Chauvet A, Rbah-Vidal L (2023)
Preclinical Evaluation of a ⁶⁴Cu-Based Theranostic Approach in a Murine Model of Multiple Myeloma
15 (7)
DOI 10.3390/pharmaceutics15071817, PubMed 37514004

Tjärnhage E, Brown D, Bogen B, Andersen TK, Grødeland G (2023)
Trimeric, APC-Targeted Subunit Vaccines Protect Mice against Seasonal and Pandemic Influenza
97 (2), e0169422
DOI 10.1128/jvi.01694-22, PubMed 36719241

Werninghaus IC, Hinke DM, Fossum E, Bogen B, Braathen R (2023)
Neuraminidase delivered as an APC-targeted DNA vaccine induces protective antibodies against influenza
31 (7), 2188-2205
DOI 10.1016/j.ymthe.2023.03.012, PubMed 36926694

Westhrin M, Blazevski J, Textor A, Abdollahi P, Gopalakrishnan RP, Ngo LT, Hofgaard PO, Heinzelbecker J, Bobic S, Fossum E, Spång HCL, Braathen R, Bogen B (2023)
Id-neoantigen vaccine induces therapeutic CD8⁺ T cells against multiple myeloma: H chain-loss escapees cause FLC MM
11 (8)
DOI 10.1136/jitc-2023-006944, PubMed 37607769

Publications 2022

Bekri S, Rodney-Sandy R, Gruenstein D, Mei A, Bogen B, Castle J, Levey D, Cho HJ (2022)
Neoantigen vaccine-induced CD4 T cells confer protective immunity in a mouse model of multiple myeloma through activation of CD8 T cells against non-vaccine, tumor-associated antigens
10 (2)
DOI 10.1136/jitc-2021-003572, PubMed 35190376

Gjesdal BE, Mæland S, Bogen B, Cumming KT, Nesse VC, Torberntsson SMR, Rygh CB (2022)
Ballistic strength training in adults with cerebral palsy may increase rate of force development in plantar flexors, but transition to walking remains unclear: a case series
14 (1), 101
DOI 10.1186/s13102-022-00487-1, PubMed 35659348

Hinke DM, Andersen TK, Gopalakrishnan RP, Skullerud LM, Werninghaus IC, Grødeland G, Fossum E, Braathen R, Bogen B (2022)
Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses
39 (9), 110901
DOI 10.1016/j.celrep.2022.110901, PubMed 35649357

Jung K, Jeon YK, Jeong DH, Byun JM, Bogen B, Choi I (2022)
VSIG4-expressing tumor-associated macrophages impair anti-tumor immunity
628, 18-24
DOI 10.1016/j.bbrc.2022.08.055, PubMed 36063598

Lopes R, Caetano J, Barahona F, Pestana C, Ferreira BV, Lourenço D, Queirós AC, Bilreiro C, Shemesh N, Beck HC, Carvalho AS, Matthiesen R, Bogen B, Costa-Silva B, Serre K, Carneiro EA, João C (2022)
Multiple Myeloma-Derived Extracellular Vesicles Modulate the Bone Marrow Immune Microenvironment
13, 909880
DOI 10.3389/fimmu.2022.909880, PubMed 35874665

Tesfaye DY, Bobic S, Lysén A, Huszthy PC, Gudjonsson A, Braathen R, Bogen B, Fossum E (2022)
Targeting Xcr1 on Dendritic Cells Rapidly Induce Th1-Associated Immune Responses That Contribute to Protection Against Influenza Infection
13, 752714
DOI 10.3389/fimmu.2022.752714, PubMed 35296089

Publications 2021

Andersen TK, Bodin J, Oftung F, Bogen B, Mjaaland S, Grødeland G (2021)
Pandemic Preparedness Against Influenza: DNA Vaccine for Rapid Relief
12, 747032
DOI 10.3389/fimmu.2021.747032, PubMed 34691056

Bjerkan L, Visweswaran GRR, Gudjonsson A, Labbé GM, Quinkert D, Pattinson DJ, Spång HCL, Draper SJ, Bogen B, Braathen R (2021)
APC-Targeted DNA Vaccination Against Reticulocyte-Binding Protein Homolog 5 Induces Plasmodium falciparum-Specific Neutralizing Antibodies and T Cell Responses
12, 720550
DOI 10.3389/fimmu.2021.720550, PubMed 34733274

He L, Valignat MP, Zhang L, Gelard L, Zhang F, Le Guen V, Audebert S, Camoin L, Fossum E, Bogen B, Wang H, Henri S, Roncagalli R, Theodoly O, Liang Y, Malissen M, Malissen B (2021)
ARHGAP45 controls naïve T- and B-cell entry into lymph nodes and T-cell progenitor thymus seeding
22 (4), e52196
DOI 10.15252/embr.202052196, PubMed 33719206

Høydahl LS, Frigstad T, Rasmussen IB, Øynebråten I, Schjetne KW, Andersen JT, Michaelsen TE, Lunde E, Bogen B, Sandlie I (2021)
Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses
39 (11), 1583-1592
DOI 10.1016/j.vaccine.2021.02.012, PubMed 33612340

Lysén A, Gudjonsson A, Tesfaye DY, Bobic S, Bern M, Bogen B, Fossum E (2021)
Intranasal delivery of a cDC1 targeted influenza vaccine with poly(I:C) enhances T cell responses and protects against influenza infection
95 (3), e13128
DOI 10.1111/sji.13128, PubMed 34923667

Szodoray P, Andersen TK, Heinzelbecker J, Imbery JF, Huszthy PC, Stanford SM, Bogen B, Landsverk OB, Bottini N, Tveita A, Munthe LA, Nakken B (2021)
Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity
36 (6), 109525
DOI 10.1016/j.celrep.2021.109525, PubMed 34380042

Ziouti F, Rummler M, Steyn B, Thiele T, Seliger A, Duda GN, Bogen B, Willie BM, Jundt F (2021)
Prevention of Bone Destruction by Mechanical Loading Is Not Enhanced by the Bruton's Tyrosine Kinase Inhibitor CC-292 in Myeloma Bone Disease
Int. J. Mol. Sci., 22 (8), 3840
DOI 10.3390/ijms22083840

Publications 2020

Braathen R, Spång HCL, Hinke DM, Blazevski J, Bobic S, Fossum E, Bogen B (2020)
A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza
17, 378-392
DOI 10.1016/j.omtm.2020.01.007, PubMed 32128342

Fossum E, Tesfaye DY, Bobic S, Gudjonsson A, Braathen R, Lahoud MH, Caminschi I, Bogen B (2020)
Targeting Antigens to Different Receptors on Conventional Type 1 Dendritic Cells Impacts the Immune Response
205 (3), 661-673
DOI 10.4049/jimmunol.1901119, PubMed 32591401

Grødeland G, Baranowska-Hustad M, Abadejos J, Blane TR, Teijaro J, Nemazee D, Bogen B (2020)
Induction of Cross-Reactive and Protective Antibody Responses After DNA Vaccination With MHCII-Targeted Stem Domain From Influenza Hemagglutinin
11, 431
DOI 10.3389/fimmu.2020.00431, PubMed 32269566

Haabeth OAW, Hennig K, Fauskanger M, Løset GÅ, Bogen B, Tveita A (2020)
CD4+ T-cell killing of multiple myeloma cells is mediated by resident bone marrow macrophages
4 (12), 2595-2605
DOI 10.1182/bloodadvances.2020001434, PubMed 32544236

Kwon M, Kim CG, Lee H, Cho H, Kim Y, Lee EC, Choi SJ, Park J, Seo IH, Bogen B, Song IC, Jo DY, Kim JS, Park SH, Choi I, Choi YS, Shin EC (2020)
PD-1 Blockade Reinvigorates Bone Marrow CD8⁺ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors
26 (7), 1644-1655
DOI 10.1158/1078-0432.CCR-19-0267, PubMed 31941832

Lysén A, Braathen R, Gudjonsson A, Tesfaye DY, Bogen B, Fossum E (2020)
Author Correction: Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
10 (1), 5944
DOI 10.1038/s41598-020-62688-3, PubMed 32231213

Rummler M, Ziouti F, Bouchard AL, Brandl A, Duda GN, Bogen B, Beilhack A, Lynch ME, Jundt F, Willie BM (2020)
Mechanical loading prevents bone destruction and exerts anti-tumor effects in the MOPC315.BM.Luc model of myeloma bone disease
119, 247-258
DOI 10.1016/j.actbio.2020.10.041, PubMed 33130307

Ziouti F, Soares AP, Moreno-Jiménez I, Rack A, Bogen B, Cipitria A, Zaslansky P, Jundt F (2020)
An Early Myeloma Bone Disease Model in Skeletally Mature Mice as a Platform for Biomaterial Characterization of the Extracellular Matrix
2020, 3985315
DOI 10.1155/2020/3985315, PubMed 32684931

Publications 2019

Andersen TK, Huszthy PC, Gopalakrishnan RP, Jacobsen JT, Fauskanger M, Tveita AA, Grødeland G, Bogen B (2019)
Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules
4, 9
DOI 10.1038/s41541-019-0101-0, PubMed 30775000

Baghdadi M, Ishikawa K, Nakanishi S, Murata T, Umeyama Y, Kobayashi T, Kameda Y, Endo H, Wada H, Bogen B, Yamamoto S, Yamaguchi K, Kasahara I, Iwasaki H, Takahata M, Ibata M, Takahashi S, Goto H, Teshima T, Seino K (2019)
A role for IL-34 in osteolytic disease of multiple myeloma
Blood Adv., 3 (4), 541-551
DOI 10.1182/bloodadvances.2018020008

Bogen B, Fauskanger M, Haabeth OA, Tveita A (2019)
CD4⁺ T cells indirectly kill tumor cells via induction of cytotoxic macrophages in mouse models
68 (11), 1865-1873
DOI 10.1007/s00262-019-02374-0, PubMed 31448380

Grodeland G, Fossum E, Bogen B (2019)
Targeting of HA to chemokine receptors induces strong and cross-reactive T cell responses after DNA vaccination in pigs
38 (6), 1280-1285
DOI 10.1016/j.vaccine.2019.11.084, PubMed 31836256

Gudjonsson A, Andersen TK, Sundvold-Gjerstad V, Bogen B, Fossum E (2019)
Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice
10, 1086
DOI 10.3389/fimmu.2019.01086, PubMed 31156636

Huszthy PC, Gopalakrishnan RP, Jacobsen JT, Haabeth OAW, Løset GÅ, Braathen R, Schenck K, Tveita AA, Munthe LA, Bogen B (2019)
B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells
116 (51), 25850-25859
DOI 10.1073/pnas.1902836116, PubMed 31796587

Høglund RA, Torsetnes SB, Lossius A, Bogen B, Homan EJ, Bremel R, Holmøy T (2019)
Human Cysteine Cathepsins Degrade Immunoglobulin G In Vitro in a Predictable Manner
20 (19)
DOI 10.3390/ijms20194843, PubMed 31569504

Lysén A, Braathen R, Gudjonsson A, Tesfaye DY, Bogen B, Fossum E (2019)
Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
9 (1), 1820
DOI 10.1038/s41598-018-38080-7, PubMed 30755656

Mahalunkar S, Yadav AS, Gorain M, Pawar V, Braathen R, Weiss S, Bogen B, Gosavi SW, Kundu GC (2019)
Functional design of pH-responsive folate-targeted polymer-coated gold nanoparticles for drug delivery and in vivo therapy in breast cancer
14, 8285-8302
DOI 10.2147/IJN.S215142, PubMed 31802866

Mooij P, Grødeland G, Koopman G, Andersen TK, Mortier D, Nieuwenhuis IG, Verschoor EJ, Fagrouch Z, Bogers WM, Bogen B (2019)
Needle-free delivery of DNA: Targeting of hemagglutinin to MHC class II molecules protects rhesus macaques against H1N1 influenza
37 (6), 817-826
DOI 10.1016/j.vaccine.2018.12.049, PubMed 30638800

Tesfaye DY, Gudjonsson A, Bogen B, Fossum E (2019)
Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses
10, 1529
DOI 10.3389/fimmu.2019.01529, PubMed 31333661

Publications 2018

Abrahamsen G, Sundvold-Gjerstad V, Habtamu M, Bogen B, Spurkland A (2018)
Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd
8 (1), 13319
DOI 10.1038/s41598-018-31510-6, PubMed 30190583

Anderson AM, Baranowska-Hustad M, Braathen R, Grodeland G, Bogen B (2018)
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
200 (6), 2057-2066
DOI 10.4049/jimmunol.1701088, PubMed 29427414

Braathen R, Spång HCL, Lindeberg MM, Fossum E, Grødeland G, Fredriksen AB, Bogen B (2018)
The Magnitude and IgG Subclass of Antibodies Elicited by Targeted DNA Vaccines Are Influenced by Specificity for APC Surface Molecules
2 (1), 38-53
DOI 10.4049/immunohorizons.1700038, PubMed 31022690

Fauskanger M, Haabeth OAW, Skjeldal FM, Bogen B, Tveita AA (2018)
Tumor Killing by CD4⁺ T Cells Is Mediated via Induction of Inducible Nitric Oxide Synthase-Dependent Macrophage Cytotoxicity
9, 1684
DOI 10.3389/fimmu.2018.01684, PubMed 30083157

Haabeth OAW, Fauskanger M, Manzke M, Lundin KU, Corthay A, Bogen B, Tveita AA (2018)
CD4⁺ T-cell-Mediated Rejection of MHC Class II-Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs
78 (16), 4573-4585
DOI 10.1158/0008-5472.CAN-17-2426, PubMed 29752262

Publications 2017

Andersen TK, Zhou F, Cox R, Bogen B, Grodeland G (2017)
A DNA Vaccine That Targets Hemagglutinin to Antigen-Presenting Cells Protects Mice against H7 Influenza
J. Virol., 91 (23), e01340-17
DOI 10.1128/JVI.01340-17

Deloizy C, Fossum E, Barnier-Quer C, Urien C, Chrun T, Duval A, Codjovi M, Bouguyon E, Maisonnasse P, Hervé PL, Barc C, Boulesteix O, Pezant J, Chevalier C, Collin N, Dalod M, Bogen B, Bertho N, Schwartz-Cornil I (2017)
The anti-influenza M2e antibody response is promoted by XCR1 targeting in pig skin
7 (1), 7639
DOI 10.1038/s41598-017-07372-9, PubMed 28794452

Gudjonsson A, Lysén A, Balan S, Sundvold-Gjerstad V, Arnold-Schrauf C, Richter L, Bækkevold ES, Dalod M, Bogen B, Fossum E (2017)
Targeting Influenza Virus Hemagglutinin to Xcr1⁺ Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses
198 (7), 2785-2795
DOI 10.4049/jimmunol.1601881, PubMed 28228559

Høglund RA, Lossius A, Johansen JN, Homan J, Benth JŠ, Robins H, Bogen B, Bremel RD, Holmøy T (2017)
In Silico Prediction Analysis of Idiotope-Driven T-B Cell Collaboration in Multiple Sclerosis
8, 1255
DOI 10.3389/fimmu.2017.01255, PubMed 29038659

Park BM, Kim EJ, Nam HJ, Zhang D, Bae CH, Kang M, Kim H, Lee W, Bogen B, Lim SK (2017)
Cyclized Oligopeptide Targeting LRP5/6-DKK1 Interaction Reduces the Growth of Tumor Burden in a Multiple Myeloma Mouse Model
Yonsei Med. J., 58 (3), 505-513
DOI 10.3349/ymj.2017.58.3.505

Wang D, Fløisand Y, Myklebust CV, Bürgler S, Parente-Ribes A, Hofgaard PO, Bogen B, Taskén K, Tjønnfjord GE, Schjesvold F, Dalgaard J, Tveita A, Munthe LA (2017)
Autologous bone marrow Th cells can support multiple myeloma cell proliferation in vitro and in xenografted mice
31 (10), 2114-2121
DOI 10.1038/leu.2017.69, PubMed 28232741

Publications 2016

Andersen AN, Landsverk OJ, Simonsen A, Bogen B, Corthay A, Øynebråten I (2016)
Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity
7, 167
DOI 10.3389/fimmu.2016.00167, PubMed 27242780

Ardouin L, Luche H, Chelbi R, Carpentier S, Shawket A, Montanana Sanchis F, Santa Maria C, Grenot P, Alexandre Y, Grégoire C, Fries A, Vu Manh TP, Tamoutounour S, Crozat K, Tomasello E, Jorquera A, Fossum E, Bogen B, Azukizawa H, Bajenoff M, Henri S, Dalod M, Malissen B (2016)
Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery
45 (2), 305-18
DOI 10.1016/j.immuni.2016.07.019, PubMed 27533013

Bartee E, Bartee MY, Bogen B, Yu XZ (2016)
Systemic therapy with oncolytic myxoma virus cures established residual multiple myeloma in mice
3, 16032
DOI 10.1038/mto.2016.32, PubMed 27933316

Deloizy C, Bouguyon E, Fossum E, Sebo P, Osicka R, Bole A, Pierres M, Biacchesi S, Dalod M, Bogen B, Bertho N, Schwartz-Cornil I (2016)
Expanding the tools for identifying mononuclear phagocyte subsets in swine: Reagents to porcine CD11c and XCR1
65, 31-40
DOI 10.1016/j.dci.2016.06.015, PubMed 27345169

Grodeland G, Fredriksen AB, Løset GÅ, Vikse E, Fugger L, Bogen B (2016)
Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination
197 (9), 3575-3585
DOI 10.4049/jimmunol.1600893, PubMed 27671110

Guilliams M, Dutertre CA, Scott CL, McGovern N, Sichien D, Chakarov S, Van Gassen S, Chen J, Poidinger M, De Prijck S, Tavernier SJ, Low I, Irac SE, Mattar CN, Sumatoh HR, Low GHL, Chung TJK, Chan DKH, Tan KK, Hon TLK, Fossum E, Bogen B, Choolani M, Chan JKY, Larbi A et al. (2016)
Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species
45 (3), 669-684
DOI 10.1016/j.immuni.2016.08.015, PubMed 27637149

Lambert L, Kinnear E, McDonald JU, Grodeland G, Bogen B, Stubsrud E, Lindeberg MM, Fredriksen AB, Tregoning JS (2016)
DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8(+) T Cell Responses, Enabling Faster Resolution of Influenza Disease
7, 321
DOI 10.3389/fimmu.2016.00321, PubMed 27602032

Lilly CL, Villa NY, Lemos de Matos A, Ali HM, Dhillon JS, Hofland T, Rahman MM, Chan W, Bogen B, Cogle C, McFadden G (2016)
Ex Vivo Oncolytic Virotherapy with Myxoma Virus Arms Multiple Allogeneic Bone Marrow Transplant Leukocytes to Enhance Graft versus Tumor
4, 31-40
DOI 10.1016/j.omto.2016.12.002, PubMed 28345022

Lorvik KB, Hammarström C, Fauskanger M, Haabeth OA, Zangani M, Haraldsen G, Bogen B, Corthay A (2016)
Adoptive Transfer of Tumor-Specific Th2 Cells Eradicates Tumors by Triggering an In Situ Inflammatory Immune Response
76 (23), 6864-6876
DOI 10.1158/0008-5472.CAN-16-1219, PubMed 27634753

Tveita A, Fauskanger M, Bogen B, Haabeth OA (2016)
Tumor-specific CD4+ T cells eradicate myeloma cells genetically deficient in MHC class II display
7 (41), 67175-67182
DOI 10.18632/oncotarget.11946, PubMed 27626487

Zhou P, Chionh YT, Irac SE, Ahn M, Jia Ng JH, Fossum E, Bogen B, Ginhoux F, Irving AT, Dutertre CA, Wang LF (2016)
Unlocking bat immunology: establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages
6, 38597
DOI 10.1038/srep38597, PubMed 27934903

Publications 2015

Baranowska M, Hauge AG, Hoornaert C, Bogen B, Grødeland G (2015)
Targeting of nucleoprotein to chemokine receptors by DNA vaccination results in increased CD8(+)-mediated cross protection against influenza
33 (49), 6988-96
DOI 10.1016/j.vaccine.2015.08.094, PubMed 26387432

Grødeland G, Bogen B (2015)
Efficient vaccine against pandemic influenza: combining DNA vaccination and targeted delivery to MHC class II molecules
14 (6), 805-14
DOI 10.1586/14760584.2015.1029919, PubMed 25818107

Grødeland G, Fossum E, Bogen B (2015)
Polarizing T and B Cell Responses by APC-Targeted Subunit Vaccines
6, 367
DOI 10.3389/fimmu.2015.00367, PubMed 26257735

Haabeth OA, Lorvik KB, Yagita H, Bogen B, Corthay A (2015)
Interleukin-1 is required for cancer eradication mediated by tumor-specific Th1 cells
5 (1), e1039763
DOI 10.1080/2162402X.2015.1039763, PubMed 26942052

Haabeth OA, Tveita A, Fauskanger M, Hennig K, Hofgaard PO, Bogen B (2015)
Idiotype-specific CD4(+) T cells eradicate disseminated myeloma
30 (5), 1216-20
DOI 10.1038/leu.2015.278, PubMed 26449664

Kikuchi J, Koyama D, Wada T, Izumi T, Hofgaard PO, Bogen B, Furukawa Y (2015)
Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma
J. Clin. Invest., 125 (12), 4375-4390
DOI 10.1172/JCI80325

Kulkarni U, Karsten CM, Kohler T, Hammerschmidt S, Bommert K, Tiburzy B, Meng L, Thieme L, Recke A, Ludwig RJ, Pollok K, Kalies K, Bogen B, Boettcher M, Kamradt T, Hauser AE, Langer C, Huber-Lang M, Finkelman FD, Köhl J, Wong DM, Manz RA (2015)
IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration
137 (5), 1487-1497.e6
DOI 10.1016/j.jaci.2015.10.018, PubMed 26653800

Matthes T, Manfroi B, Zeller A, Dunand-Sauthier I, Bogen B, Huard B (2015)
Autocrine amplification of immature myeloid cells by IL-6 in multiple myeloma-infiltrated bone marrow
Leukemia, 29 (9), 1882-1890
DOI 10.1038/leu.2015.145

Parente-Ribes A, Skånland SS, Bürgler S, Os A, Wang D, Bogen B, Tjønnfjord GE, Taskén K, Munthe LA (2015)
Spleen tyrosine kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells
101 (2), e59-62
DOI 10.3324/haematol.2015.135590, PubMed 26589914

Terhorst D, Fossum E, Baranska A, Tamoutounour S, Malosse C, Garbani M, Braun R, Lechat E, Crameri R, Bogen B, Henri S, Malissen B (2015)
Laser-assisted intradermal delivery of adjuvant-free vaccines targeting XCR1+ dendritic cells induces potent antitumoral responses
194 (12), 5895-902
DOI 10.4049/jimmunol.1500564, PubMed 25941327

Tveita AA, Schjesvold F, Haabeth OA, Fauskanger M, Bogen B (2015)
Tumors Escape CD4+ T-cell-Mediated Immunosurveillance by Impairing the Ability of Infiltrating Macrophages to Indirectly Present Tumor Antigens
75 (16), 3268-78
DOI 10.1158/0008-5472.CAN-14-3640, PubMed 26038231

Aas-Hanssen K, Thompson KM, Bogen B, Munthe LA (2015)
Systemic Lupus Erythematosus: Molecular Mimicry between Anti-dsDNA CDR3 Idiotype, Microbial and Self Peptides-As Antigens for Th Cells
6, 382
DOI 10.3389/fimmu.2015.00382, PubMed 26284067

Publications 2014

Balan S, Ollion V, Colletti N, Chelbi R, Montanana-Sanchis F, Liu H, Vu Manh TP, Sanchez C, Savoret J, Perrot I, Doffin AC, Fossum E, Bechlian D, Chabannon C, Bogen B, Asselin-Paturel C, Shaw M, Soos T, Caux C, Valladeau-Guilemond J, Dalod M (2014)
Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells
193 (4), 1622-35
DOI 10.4049/jimmunol.1401243, PubMed 25009205

Binsfeld M, Beguin Y, Belle L, Otjacques E, Hannon M, Briquet A, Heusschen R, Drion P, Zilberberg J, Bogen B, Baron F, Caers J (2014)
Establishment of a murine graft-versus-myeloma model using allogeneic stem cell transplantation
9 (11), e113764
DOI 10.1371/journal.pone.0113764, PubMed 25415267

Bürgler S, Gimeno A, Parente-Ribes A, Wang D, Os A, Devereux S, Jebsen P, Bogen B, Tjønnfjord GE, Munthe LA (2014)
Chronic lymphocytic leukemia cells express CD38 in response to Th1 cell-derived IFN-γ by a T-bet-dependent mechanism
194 (2), 827-35
DOI 10.4049/jimmunol.1401350, PubMed 25505279

Dutertre CA, Jourdain JP, Rancez M, Amraoui S, Fossum E, Bogen B, Sanchez C, Couëdel-Courteille A, Richard Y, Dalod M, Feuillet V, Cheynier R, Hosmalin A (2014)
TLR3-responsive, XCR1+, CD141(BDCA-3)+/CD8α+-equivalent dendritic cells uncovered in healthy and simian immunodeficiency virus-infected rhesus macaques
192 (10), 4697-708
DOI 10.4049/jimmunol.1302448, PubMed 24740505

Fossum E, Grødeland G, Terhorst D, Tveita AA, Vikse E, Mjaaland S, Henri S, Malissen B, Bogen B (2014)
Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8+ T-cell responses against influenza virus
45 (2), 624-35
DOI 10.1002/eji.201445080, PubMed 25410055

Haabeth OA, Tveita AA, Fauskanger M, Schjesvold F, Lorvik KB, Hofgaard PO, Omholt H, Munthe LA, Dembic Z, Corthay A, Bogen B (2014)
How Do CD4(+) T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?
5, 174
DOI 10.3389/fimmu.2014.00174, PubMed 24782871

Jacobsen J, Haabeth OA, Tveita AA, Schjetne KW, Munthe LA, Bogen B (2014)
Naive idiotope-specific B and T cells collaborate efficiently in the absence of dendritic cells
192 (9), 4174-83
DOI 10.4049/jimmunol.1302359, PubMed 24706724

Løvås TO, Bruusgaard JC, Øynebråten I, Gundersen K, Bogen B (2014)
DNA vaccines: MHC II-targeted vaccine protein produced by transfected muscle fibres induces a local inflammatory cell infiltrate in mice
9 (10), e108069
DOI 10.1371/journal.pone.0108069, PubMed 25299691

Ruffini PA, Os A, Dolcetti R, Tjønnfjord GE, Munthe LA, Bogen B (2014)
Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice
12, 207
DOI 10.1186/1479-5876-12-207, PubMed 25059102

Schwarzer R, Nickel N, Godau J, Willie BM, Duda GN, Schwarzer R, Cirovic B, Leutz A, Manz R, Bogen B, Dörken B, Jundt F (2014)
Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model
4 (6), e217
DOI 10.1038/bcj.2014.37, PubMed 24927406

Tveita AA, Haabeth OA, Bogen B (2014)
Limitations of bystander killing in Th1/M1 immune responses against a secreted tumor antigen
3 (9), e954953
DOI 10.4161/21624011.2014.954953, PubMed 25941607

Tveita AA, Schjesvold FH, Sundnes O, Haabeth OA, Haraldsen G, Bogen B (2014)
Indirect CD4+ T-cell-mediated elimination of MHC II(NEG) tumor cells is spatially restricted and fails to prevent escape of antigen-negative cells
44 (9), 2625-37
DOI 10.1002/eji.201444659, PubMed 24846412

Wong D, Winter O, Hartig C, Siebels S, Szyska M, Tiburzy B, Meng L, Kulkarni U, Fähnrich A, Bommert K, Bargou R, Berek C, Chu VT, Bogen B, Jundt F, Manz RA (2014)
Eosinophils and megakaryocytes support the early growth of murine MOPC315 myeloma cells in their bone marrow niches
9 (10), e109018
DOI 10.1371/journal.pone.0109018, PubMed 25272036

Øynebråten I, Hinkula J, Fredriksen AB, Bogen B (2014)
Increased generation of HIV-1 gp120-reactive CD8+ T cells by a DNA vaccine construct encoding the chemokine CCL3
9 (8), e104814
DOI 10.1371/journal.pone.0104814, PubMed 25122197

Aas-Hanssen K, Funderud A, Thompson KM, Bogen B, Munthe LA (2014)
Idiotype-specific Th cells support oligoclonal expansion of anti-dsDNA B cells in mice with lupus
193 (6), 2691-8
DOI 10.4049/jimmunol.1400640, PubMed 25127856

Publications 2013

Frigstad T, Løset GÅ, Sandlie I, Bogen B (2013)
A public T cell receptor recognized by a monoclonal antibody specific for the D-J junction of the β-chain
78 (4), 345-51
DOI 10.1111/sji.12098, PubMed 23841814

Grodeland G, Mjaaland S, Roux KH, Fredriksen AB, Bogen B (2013)
DNA vaccine that targets hemagglutinin to MHC class II molecules rapidly induces antibody-mediated protection against influenza
191 (6), 3221-31
DOI 10.4049/jimmunol.1300504, PubMed 23956431

Grødeland G, Mjaaland S, Tunheim G, Fredriksen AB, Bogen B (2013)
The specificity of targeted vaccines for APC surface molecules influences the immune response phenotype
8 (11), e80008
DOI 10.1371/journal.pone.0080008, PubMed 24244595

Gunnarsen KS, Kristinsson SG, Justesen S, Frigstad T, Buus S, Bogen B, Sandlie I, Loset GA (2013)
Chaperone-assisted thermostability engineering of a soluble T cell receptor using phage display
Sci Rep, 3, 1162
DOI 10.1038/srep01162

Heimberger T, Andrulis M, Riedel S, Stuhmer T, Schraud H, Beilhack A, Bumm T, Bogen B, Einsele H, Bargou RC, Chatterjee M (2013)
The heat shock transcription factor 1 as a potential new therapeutic target in multiple myeloma
Br. J. Haematol., 160 (4), 465-476
DOI 10.1111/bjh.12164

Hong S, Lee H, Jung K, Lee SM, Lee SJ, Jun HJ, Kim Y, Song H, Bogen B, Choi I (2013)
Tumor cells loaded with alpha-galactosylceramide promote therapeutic NKT-dependent anti-tumor immunity in multiple myeloma
Immunol. Lett., 156 (1-2), 132-139
DOI 10.1016/j.imlet.2013.10.002

Jacobsen JT, Sundvold-Gjerstad V, Skjeldal FM, Andersen JT, Abrahamsen G, Bakke O, Spurkland A, Bogen B (2013)
B-cell tolerance to the B-cell receptor variable regions
43 (10), 2577-87
DOI 10.1002/eji.201243203, PubMed 23839948

Lorvik KB, Haabeth OA, Clancy T, Bogen B, Corthay A (2013)
Molecular profiling of tumor-specific T_H1 cells activated in vivo
2 (5), e24383
DOI 10.4161/onci.24383, PubMed 23762808

Os A, Bürgler S, Ribes AP, Funderud A, Wang D, Thompson KM, Tjønnfjord GE, Bogen B, Munthe LA (2013)
Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells
4 (3), 566-77
DOI 10.1016/j.celrep.2013.07.011, PubMed 23933259

Publications 2012

Berge T, Gronningsaeter IHB, Lorvik KB, Abrahamsen G, Granum S, Sundvold-Gjerstad V, Corthay A, Bogen B, Spurkland A (2012)
SH2D2A Modulates T Cell Mediated Protection to a B Cell Derived Tumor in Transgenic Mice
PLoS One, 7 (10), e48239
DOI 10.1371/journal.pone.0048239

Fredriksen AB, Sandlie I, Bogen B (2012)
Targeted DNA vaccines for enhanced induction of idiotype-specific B and T cells
2, 154
DOI 10.3389/fonc.2012.00154, PubMed 23115759

Hofgaard PO, Jodal HC, Bommert K, Huard B, Caers J, Carlsen H, Schwarzer R, Schünemann N, Jundt F, Lindeberg MM, Bogen B (2012)
A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease
7 (12), e51892
DOI 10.1371/journal.pone.0051892, PubMed 23284805

Haabeth OA, Bogen B, Corthay A (2012)
A model for cancer-suppressive inflammation
1 (7), 1146-1155
DOI 10.4161/onci.21542, PubMed 23170261

Lorvik KB, Bogen B, Corthay A (2012)
Fingolimod blocks immunosurveillance of myeloma and B-cell lymphoma resulting in cancer development in mice
Blood, 119 (9), 2176-2177
DOI 10.1182/blood-2011-10-388892

Nilssen NR, Frigstad T, Pollmann S, Roos N, Bogen B, Sandlie I, Løset GÅ (2012)
DeltaPhage--a novel helper phage for high-valence pIX phagemid display
40 (16), e120
DOI 10.1093/nar/gks341, PubMed 22539265

Oynebraten I, Lovas TO, Thompson K, Bogen B (2012)
Generation of Antibody-Producing Hybridomas Following One Single Immunization with a Targeted DNA Vaccine
Scand. J. Immunol., 75 (4), 379-388
DOI 10.1111/j.1365-3083.2011.02639.x

Rasmussen IB, Oynebråten I, Høydahl LS, Flobakk M, Lunde E, Michaelsen TE, Bogen B, Sandlie I (2012)
CD40/APC-specific antibodies with three T-cell epitopes loaded in the constant domains induce CD4+ T-cell responses
25 (3), 89-96
DOI 10.1093/protein/gzr063, PubMed 22233931

Riedel SS, Mottok A, Brede C, Bauerlein CA, Garrote ALJ, Ritz M, Mattenheimer K, Rosenwald A, Einsele H, Bogen B, Beilhack A (2012)
Non-Invasive Imaging Provides Spatiotemporal Information on Disease Progression and Response to Therapy in a Murine Model of Multiple Myeloma
PLoS One, 7 (12), e52398
DOI 10.1371/journal.pone.0052398

Spång HC, Braathen R, Bogen B (2012)
Heterodimeric barnase-barstar vaccine molecules: influence of one versus two targeting units specific for antigen presenting cells
7 (9), e45393
DOI 10.1371/journal.pone.0045393, PubMed 23028981

Publications 2011

Bogen B (2011)
Lymphoma invisibility-vaccination-attack?
Blood, 117 (5), 1437-1438
DOI 10.1182/blood-2010-11-318469

Bogen B (2011)
Welcome to the 40th Scandinavian Society for Immunology meeting at Geilo, Norway
Scand. J. Immunol., 73 (4), 267
DOI 10.1111/j.1365-3083.2011.02509.x

Corthay A, Lorvik KB, Bogen B (2011)
Is secretion of tumour-specific antigen important for cancer eradication by CD4(+) T cells?--Implications for cancer immunotherapy by adoptive T cell transfer
73 (6), 527-30
DOI 10.1111/j.1365-3083.2011.02558.x, PubMed 21388431

Crozat K, Tamoutounour S, Vu Manh TP, Fossum E, Luche H, Ardouin L, Guilliams M, Azukizawa H, Bogen B, Malissen B, Henri S, Dalod M (2011)
Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α+ type
187 (9), 4411-5
DOI 10.4049/jimmunol.1101717, PubMed 21948982

Follin-Arbelet V, Hofgaard PO, Hauglin H, Naderi S, Sundan A, Blomhoff R, Bogen B, Blomhoff HK (2011)
Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model
11, 301
DOI 10.1186/1471-2407-11-301, PubMed 21767374

Frøyland M, Ruffini PA, Thompson KM, Gedde-Dahl T, Fredriksen AB, Bogen B (2011)
Targeted idiotype-fusion DNA vaccines for human multiple myeloma: preclinical testing
86 (5), 385-95
DOI 10.1111/j.1600-0609.2011.01590.x, PubMed 21332794

Haabeth OA, Lorvik KB, Hammarström C, Donaldson IM, Haraldsen G, Bogen B, Corthay A (2011)
Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer
2, 240
DOI 10.1038/ncomms1239, PubMed 21407206

Loset GA, Bogen B, Sandlie I (2011)
Expanding the Versatility of Phage Display I: Efficient Display of Peptide-Tags on Protein VII of the Filamentous Phage
PLoS One, 6 (2), e14702
DOI 10.1371/journal.pone.0014702

Loset GA, Roos N, Bogen B, Sandlie I (2011)
Expanding the Versatility of Phage Display II: Improved Affinity Selection of Folded Domains on Protein VII and IX of the Filamentous Phage
PLoS One, 6 (2), e17433
DOI 10.1371/journal.pone.0017433

Publications 2010

Gunnarsen KS, Lunde E, Kristiansen PE, Bogen B, Sandlie I, Loset GA (2010)
Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA
BMC Biotechnol., 10, 8
DOI 10.1186/1472-6750-10-8

Jacobsen JT, Lunde E, Sundvold-Gjerstad V, Munthe LA, Bogen B (2010)
The cellular mechanism by which complementary Id+ and anti-Id antibodies communicate: T cells integrated into idiotypic regulation
88 (5), 515-22
DOI 10.1038/icb.2009.118, PubMed 20066000

Lunde E, Loset GA, Bogen B, Sandlie I (2010)
Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins
BMC Biotechnol., 10, 61
DOI 10.1186/1472-6750-10-61

Ruffini PA, Grødeland G, Fredriksen AB, Bogen B (2010)
Human chemokine MIP1α increases efficiency of targeted DNA fusion vaccines
29 (2), 191-9
DOI 10.1016/j.vaccine.2010.10.057, PubMed 21055498

Publications 2009

Bogen B, Ruffini P (2009)
Review: to what extent are T cells tolerant to immunoglobulin variable regions?
70 (6), 526-30
DOI 10.1111/j.1365-3083.2009.02340.x, PubMed 19906193

Corthay A, Lundin KU, Lorvik KB, Hofgaard PO, Bogen B (2009)
Secretion of tumor-specific antigen by myeloma cells is required for cancer immunosurveillance by CD4+ T cells
69 (14), 5901-7
DOI 10.1158/0008-5472.CAN-08-4816, PubMed 19567679

Holmøy T, Vartdal F, Hestvik AL, Munthe L, Bogen B (2009)
The idiotype connection: linking infection and multiple sclerosis
31 (2), 56-62
DOI 10.1016/j.it.2009.11.001, PubMed 19962346

Zangani M, Carlsen H, Kielland A, Os A, Hauglin H, Blomhoff R, Munthe LA, Bogen B (2009)
Tracking early autoimmune disease by bioluminescent imaging of NF-kappaB activation reveals pathology in multiple organ systems
174 (4), 1358-67
DOI 10.2353/ajpath.2009.080700, PubMed 19286564

Publications 2008

Flobakk M, Rasmussen IB, Lunde E, Frigstad T, Berntzen G, Michaelsen TE, Bogen B, Sandlie I (2008)
Processing of an Antigenic Sequence from IgG Constant Domains for Presentation by MHC Class II
J. Immunol., 181 (10), 7062-7072
DOI 10.4049/jimmunol.181.10.7062

Tunheim G, Schjetne KW, Rasmussen IB, Sollid LM, Sandlie I, Bogen B (2008)
Recombinant antibodies for delivery of antigen: a single loop between beta-strands in the constant region can accommodate long, complex and tandem T cell epitopes
20 (3), 295-306
DOI 10.1093/intimm/dxm141, PubMed 18252695

Publications 2007

Bogen B, Munthe LA (2007)
Immunologi
Universitetsforl., Oslo (2. utg.), 334 s.
BIBSYS 070820953, ISBN 978-82-15-01093-9

Fredriksen AB, Bogen B (2007)
Chemokine-idiotype fusion DNA vaccines are potentiated by bivalency and xenogeneic sequences
110 (6), 1797-805
DOI 10.1182/blood-2006-06-032938, PubMed 17540847

Frøyland M, Thompson KM, Thorpe SJ, Sahota SS, Gedde-Dahl T, Bogen B (2007)
A VH4-34+ myeloma protein with weak autoreactivity
92 (5), 690-3
DOI 10.3324/haematol.10850, PubMed 17488696

Hestvik AL, Vartdal F, Fredriksen AB, Thompson KM, Kvale EO, Skorstad G, Bogen B, Holmoy T (2007)
T cells from multiple sclerosis patients recognize multiple epitopes on Self-IgG
66 (4), 393-401
DOI 10.1111/j.1365-3083.2007.01955.x, PubMed 17850583

Kolltveit KM, Granum S, Aasheim HC, Forsbring M, Sundvold-Gjerstad V, Dai KZ, Molberg O, Schjetne KW, Bogen B, Shapiro VS, Johansen FE, Schenck K, Spurkland A (2007)
Expression of SH2D2A in T-cells is regulated both at the transcriptional and translational level
45 (8), 2380-90
DOI 10.1016/j.molimm.2007.11.005, PubMed 18160104

Løset GÅ, Lunde E, Bogen B, Brekke OH, Sandlie I (2007)
Functional phage display of two murine alpha/beta T-cell receptors is strongly dependent on fusion format, mode and periplasmic folding assistance
20 (9), 461-72
DOI 10.1093/protein/gzm044, PubMed 17925331

Ráki M, Schjetne KW, Stamnaes J, Molberg Ø, Jahnsen FL, Issekutz TB, Bogen B, Sollid LM (2007)
Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells
65 (3), 213-20
DOI 10.1111/j.1365-3083.2006.01881.x, PubMed 17309775

Schjetne KW, Fredriksen AB, Bogen B (2007)
Delivery of antigen to CD40 induces protective immune responses against tumors
178 (7), 4169-76
DOI 10.4049/jimmunol.178.7.4169, PubMed 17371973

Tunheim G, Thompson KM, Fredriksen AB, Espevik T, Schjetne KW, Bogen B (2007)
Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates
25 (24), 4723-34
DOI 10.1016/j.vaccine.2007.04.004, PubMed 17499405

Zangani MM, Frøyland M, Qiu GY, Meza-Zepeda LA, Kutok JL, Thompson KM, Munthe LA, Bogen B (2007)
Lymphomas can develop from B cells chronically helped by idiotype-specific T cells
204 (5), 1181-91
DOI 10.1084/jem.20061220, PubMed 17485509

Publications 2006

Bogen B, Ruffini PA, Corthay A, Fredriksen AB, Frøyland M, Lundin K, Røsjø E, Thompson K, Massaia M (2006)
Idiotype-specific immunotherapy in multiple myeloma: suggestions for future directions of research
91 (7), 941-8
PubMed 16818282

Fredriksen AB, Sandlie I, Bogen B (2006)
DNA vaccines increase immunogenicity of idiotypic tumor antigen by targeting novel fusion proteins to antigen-presenting cells
13 (4), 776-85
DOI 10.1016/j.ymthe.2005.10.019, PubMed 16414309

Husebye H, Halaas Ø, Stenmark H, Tunheim G, Sandanger Ø, Bogen B, Brech A, Latz E, Espevik T (2006)
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
25 (4), 683-92
DOI 10.1038/sj.emboj.7600991, PubMed 16467847

Kjeken R, Bogen B, Mathiesen I (2006)
[DNA--the future in vaccine technology?]
126 (22), 2964-8
PubMed 17117196

Publications 2005

Bjordal JM, Bogen B, Lopes-Martins RAB, Klovning A (2005)
Can Cochrane reviews in controversial areas be biased? A sensitivity analysis based on the protocol of a systematic Cochrane review on low-level laser therapy in osteoarthritis
Photomed. Laser Surg., 23 (5), 453-458
DOI 10.1089/pho.2005.23.453

Corthay A, Skovseth DK, Lundin KU, Røsjø E, Omholt H, Hofgaard PO, Haraldsen G, Bogen B (2005)
Primary antitumor immune response mediated by CD4+ T cells
22 (3), 371-83
DOI 10.1016/j.immuni.2005.02.003, PubMed 15780993

Holmøy T, Fredriksen AB, Thompson KM, Hestvik AL, Bogen B, Vartdal F (2005)
Cerebrospinal fluid T cell clones from patients with multiple sclerosis: recognition of idiotopes on monoclonal IgG secreted by autologous cerebrospinal fluid B cells
35 (6), 1786-94
DOI 10.1002/eji.200425417, PubMed 15864781

Munthe LA, Corthay A, Os A, Zangani M, Bogen B (2005)
Systemic autoimmune disease caused by autoreactive B cells that receive chronic help from Ig V region-specific T cells
175 (4), 2391-400
DOI 10.4049/jimmunol.175.4.2391, PubMed 16081810

Schjetne KW, Thommesen JE, Fredriksen AB, Lunde E, Sandlie I, Bogen B (2005)
Induction of central T cell tolerance: recombinant antibodies deliver peptides for deletion of antigen-specific (CD4+)8+ thymocytes
35 (11), 3142-52
DOI 10.1002/eji.200425947, PubMed 16184515

Publications 2004

Corthay A, Lundin KU, Munthe LA, Frøyland M, Gedde-Dahl T, Dembic Z, Bogen B (2004)
Immunotherapy in multiple myeloma: Id-specific strategies suggested by studies in animal models
53 (9), 759-69
DOI 10.1007/s00262-004-0504-1, PubMed 15088126

Dembic Z, Hofgaard PO, Omholt H, Bogen B (2004)
Anti-class II antibodies, but not cytotoxic T-lymphocyte antigen 4-immunoglobulin hybrid molecules, prevent rejection of major histocompatibility complex class II-negative myeloma in T-cell receptor-transgenic mice
60 (1-2), 143-52
DOI 10.1111/j.0300-9475.2004.01435.x, PubMed 15238083

Etokebe GE, Abrahamsen TG, Bogen B, Spurkland A (2004)
Tumour necrosis factor receptor superfamily member 6 gene mutation detection by denaturing high-performance liquid chromatography
59 (5), 496-503
DOI 10.1111/j.0300-9475.2004.01422.x, PubMed 15140060

Lundin KU, Screpanti V, Omholt H, Hofgaard PO, Yagita H, Grandien A, Bogen B (2004)
CD4+ T cells kill Id+ B-lymphoma cells: FasLigand-Fas interaction is dominant in vitro but is redundant in vivo
53 (12), 1135-45
DOI 10.1007/s00262-004-0538-4, PubMed 15696611

Munthe LA, Os A, Zangani M, Bogen B (2004)
MHC-restricted Ig V region-driven T-B lymphocyte collaboration: B cell receptor ligation facilitates switch to IgG production
172 (12), 7476-84
DOI 10.4049/jimmunol.172.12.7476, PubMed 15187126

Ruffini PA, Biragyn A, Coscia M, Harvey LK, Cha SC, Bogen B, Kwak LW (2004)
Genetic fusions with viral chemokines target delivery of nonimmunogenic antigen to trigger antitumor immunity independent of chemotaxis
76 (1), 77-85
DOI 10.1189/jlb.1003481, PubMed 15075363

Tjelle TE, Corthay A, Lunde E, Sandlie I, Michaelsen TE, Mathiesen I, Bogen B (2004)
Monoclonal antibodies produced by muscle after plasmid injection and electroporation
9 (3), 328-36
DOI 10.1016/j.ymthe.2003.12.007, PubMed 15006599

Tunheim G, Schjetne KW, Fredriksen AB, Sandlie I, Bogen B (2004)
Human CD14 is an efficient target for recombinant immunoglobulin vaccine constructs that deliver T cell epitopes
77 (3), 303-10
DOI 10.1189/jlb.0804480, PubMed 15576418

Publications 2003

Dellacasagrande J, Schreurs OJ, Hofgaard PO, Omholt H, Steinsvoll S, Schenck K, Bogen B, Dembic Z (2003)
Liver metastasis of cancer facilitated by chemokine receptor CCR6
57 (6), 534-44
DOI 10.1046/j.1365-3083.2003.01263.x, PubMed 12791091

Lundin KU, Hofgaard PO, Omholt H, Munthe LA, Corthay A, Bogen B (2003)
Therapeutic effect of idiotype-specific CD4+ T cells against B-cell lymphoma in the absence of anti-idiotypic antibodies
102 (2), 605-12
DOI 10.1182/blood-2002-11-3381, PubMed 12649166

Schjetne KW, Gundersen HT, Iversen JG, Thompson KM, Bogen B (2003)
Antibody-mediated delivery of antigen to chemokine receptors on antigen-presenting cells results in enhanced CD4+ T cell responses
33 (11), 3101-8
DOI 10.1002/eji.200324299, PubMed 14579278

Schjetne KW, Thompson KM, Nilsen N, Flo TH, Fleckenstein B, Iversen JG, Espevik T, Bogen B (2003)
Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target
171 (1), 32-6
DOI 10.4049/jimmunol.171.1.32, PubMed 12816980

Publications 2002

Lunde E, Lauvrak V, Rasmussen IB, Schjetne KW, Thompson KM, Michaelsen TE, Brekke OH, Sollid LM, Bogen B, Sandlie I (2002)
Troybodies and pepbodies
30 (4), 500-6
DOI 10.1042/bst0300500, PubMed 12196123

Lunde E, Western KH, Rasmussen IB, Sandlie I, Bogen B (2002)
Efficient delivery of T cell epitopes to APC by use of MHC class II-specific Troybodies
168 (5), 2154-62
DOI 10.4049/jimmunol.168.5.2154, PubMed 11859101

Schjetne KW, Thompson KM, Aarvak T, Fleckenstein B, Sollid LM, Bogen B (2002)
A mouse C kappa-specific T cell clone indicates that DC-SIGN is an efficient target for antibody-mediated delivery of T cell epitopes for MHC class II presentation
14 (12), 1423-30
DOI 10.1093/intimm/dxf110, PubMed 12456590

Publications 2001

Dembic Z, Røttingen JA, Dellacasagrande J, Schenck K, Bogen B (2001)
Phagocytic dendritic cells from myelomas activate tumor-specific T cells at a single cell level
97 (9), 2808-14
DOI 10.1182/blood.v97.9.2808, PubMed 11313275

Lunde E, Rasmussen IB, Eidem JK, Gregers TF, Western KH, Bogen B, Sandlie I (2001)
'Troy-bodies': antibodies as vector proteins for T cell epitopes
18 (3), 109-16
DOI 10.1016/s1389-0344(01)00091-0, PubMed 11566602

McAdam SN, Fleckenstein B, Rasmussen IB, Schmid DG, Sandlie I, Bogen B, Viner NJ, Sollid LM (2001)
T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation
193 (11), 1239-46
DOI 10.1084/jem.193.11.1239, PubMed 11390431

Rasmussen IB, Lunde E, Michaelsen TE, Bogen B, Sandlie I (2001)
The principle of delivery of T cell epitopes to antigen-presenting cells applied to peptides from influenza virus, ovalbumin, and hen egg lysozyme: implications for peptide vaccination
98 (18), 10296-301
DOI 10.1073/pnas.181336898, PubMed 11517321

Publications 2000

Bogen B, Munthe LA (2000)
Immunologi
Universitetsforl., [Oslo], 295 s.
BIBSYS 991347749, ISBN 82-518-3875-4

Bogen B, Schenck K, Munthe LA, Dembic Z (2000)
Deletion of idiotype (Id)-specific T cells in multiple myeloma
39 (7), 783-8
DOI 10.1080/028418600750063505, PubMed 11145433

Bogen B, Schenck K, Munthe LA, Dembic Z (2000)
Deletion of idiotype (Id)-specific T cells in multiple myeloma
Acta Oncol., 39 (7), 783-788

Dembic Z, Schenck K, Bogen B (2000)
Dendritic cells purified from myeloma are primed with tumor-specific antigen (idiotype) and activate CD4+ T cells
97 (6), 2697-702
DOI 10.1073/pnas.050579897, PubMed 10706628

Eidem JK, Rasmussen IB, Lunde E, Gregers TF, Rees AR, Bogen B, Sandlie I (2000)
Recombinant antibodies as carrier proteins for sub-unit vaccines: influence of mode of fusion on protein production and T-cell activation
245 (1-2), 119-31
DOI 10.1016/s0022-1759(00)00274-x, PubMed 11042289

Publications 1999

Djerbi M, Screpanti V, Catrina AI, Bogen B, Biberfeld P, Grandien A (1999)
The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors
J. Exp. Med., 190 (7), 1025-1031
DOI 10.1084/jem.190.7.1025

Lunde E, Munthe LA, Vabo A, Sandlie I, Bogen B (1999)
Antibodies engineered with IgD specificity efficiently deliver integrated T-cell epitopes for antigen presentation by B cells
Nat. Biotechnol., 17 (7), 670-675
DOI 10.1038/10883

Munthe LA, Kyte JA, Bogen B (1999)
Resting small B cells present endogenous immunoglobulin variable-region determinants to idiotope-specific CD4(+) T cells in vivo
29 (12), 4043-52
DOI 10.1002/(SICI)1521-4141(199912)29:12<4043::AID-IMMU4043>3.0.CO;2-E, PubMed 10602015

Publications 1998

Dembic Z, Munthe LA, Schenck K, Mueller C, Bogen B (1998)
Transient overexpression of CD4 enhances allelic exclusion of T-cell receptor (TCR) alpha chains and promotes positive selection of class II restricted TCR-transgenic thymocytes
Mol. Immunol., 35 (1), 23-38

Engel H, Bogen B, Muller U, Andersson J, Rolink A, Weiss S (1998)
Expression level of a transgenic lambda 2 chain results in isotype exclusion and commitment to B1 cells
Eur. J. Immunol., 28 (8), 2289-2299
DOI 10.1002/(SICI)1521-4141(199808)28:08<2289::AID-IMMU2289>3.0.CO;2-Y

Lauritzsen GF, Hofgaard PO, Schenck K, Bogen B (1998)
Clonal deletion of thymocytes as a tumor escape mechanism
Int. J. Cancer, 78 (2), 216-222
DOI 10.1002/(SICI)1097-0215(19981005)78:2<216::AID-IJC16>3.0.CO;2-8

Sim BC, Aftahi N, Reilly C, Bogen B, Schwartz RH, Gascoigne NRJ, Lo D (1998)
Thymic skewing of the CD4/CD8 ratio maps with the T-cell receptor alpha-chain locus
Curr. Biol., 8 (12), 701-704
DOI 10.1016/S0960-9822(98)70276-3

Publications 1997

Lunde E, Bogen B, Sandlie I (1997)
Immunoglobulin as a vehicle for foreign antigenic peptides immunogenic to T cells
34 (16-17), 1167-76
DOI 10.1016/s0161-5890(97)00143-0, PubMed 9566764

Publications 1996

Blichfeldt E, Munthe LA, Røtnes JS, Bogen B (1996)
Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptor
26 (12), 2876-84
DOI 10.1002/eji.1830261211, PubMed 8977280

Bogen B (1996)
Peripheral T cell tolerance as a tumor escape mechanism: Deletion of CD4(+) T cells specific for a monoclonal immunoglobulin idiotype secreted by a plasmacytoma
Eur. J. Immunol., 26 (11), 2671-2679
DOI 10.1002/eji.1830261119

Bot A, Nangpal A, Pricop L, Bogen B, Kaushik A, Bona CA (1996)
V-lambda light chain genes reconstitute immune responses to defined carbohydrate antigens or haptens by utilizing different V-H genes
Mol. Immunol., 33 (17-18), 1359-1368
DOI 10.1016/S0161-5890(96)00095-8

Munthe LA, Blichfeldt E, Sollien A, Dembic Z, Bogen B (1996)
T cells with two Tcr beta chains and reactivity to both MHC/idiotypic peptide and superantigen
Cell. Immunol., 170 (2), 283-290
DOI 10.1006/cimm.1996.0162

Publications 1995

BOGEN B, MUNTHE L, SOLLIEN A, HOFGAARD P, OMHOLT H, DAGNAES F, DEMBIC Z, LAURITZSEN GF (1995)
NAIVE CD4(+) T-CELLS CONFER IDIOTYPE-SPECIFIC TUMOR RESISTANCE IN THE ABSENCE OF ANTIBODIES
Eur. J. Immunol., 25 (11), 3079-3086
DOI 10.1002/eji.1830251114

DYBWAD A, BOGEN B, NATVIG JB, FORRE O, SIOUD M (1995)
PEPTIDE PHAGE LIBRARIES CAN BE AN EFFICIENT TOOL FOR IDENTIFYING ANTIBODY LIGANDS FOR POLYCLONAL ANTISERA
Clin. Exp. Immunol., 102 (2), 438-442

Dybwad A, Bogen B, Natvig JB, Førre O, Sioud M (1995)
Peptide phage libraries can be an efficient tool for identifying antibody ligands for polyclonal antisera
102 (2), 438-42
DOI 10.1111/j.1365-2249.1995.tb03802.x, PubMed 7586703

Munthe LA, Sollien A, Dembic Z, Bogen B (1995)
Preferential positive selection of T lymphocytes which express two different TCR alpha chains, an endogenous and a transgenic
Scand. J. Immunol., 42 (6), 651-661
DOI 10.1111/j.1365-3083.1995.tb03708.x

Publications 1994

DEMBIC Z, WEISS S, BOGEN B (1994)
THYMIC SELECTION OF IMMUNOGLOBULIN IDIOTYPE SPECIFIC T-CELLS
Thymus, 22 (3), 141-152

LAURITZSEN GF, WEISS S, DEMBIC Z, BOGEN B (1994)
NAIVE IDIOTYPE-SPECIFIC CD4+ T-CELLS AND IMMUNOSURVEILLANCE OF B-CELL TUMORS
Proc. Natl. Acad. Sci. U. S. A., 91 (12), 5700-5704
DOI 10.1073/pnas.91.12.5700

Røtnes JS, Bogen B (1994)
Ca2+ mobilization in physiologically stimulated single T cells gradually increases with peptide concentration (analog signaling)
24 (4), 851-8
DOI 10.1002/eji.1830240412, PubMed 8149956

Publications 1993

BOGEN B, DEMBIC Z, WEISS S (1993)
CLONAL DELETION OF SPECIFIC THYMOCYTES BY AN IMMUNOGLOBULIN IDIOTYPE
Embo J., 12 (1), 357-363
DOI 10.1002/j.1460-2075.1993.tb05664.x

BOGEN B, GLEDITSCH L, TEIG A (1993)
T-CELL RECEPTOR ALPHA-HAPLOTYPE INFLUENCES V-ALPHA EPITOPE EXPRESSION ON BOTH CORTISONE-RESISTANT THYMOCYTES AND LYMPH-NODE T-CELLS
Scand. J. Immunol., 37 (6), 690-695
DOI 10.1111/j.1365-3083.1993.tb01685.x

LAURITZSEN GF, BOGEN B (1993)
THE ROLE OF IDIOTYPE-SPECIFIC, CD4+ T-CELLS IN TUMOR RESISTANCE AGAINST MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II MOLECULE NEGATIVE PLASMACYTOMA CELLS
Cell. Immunol., 148 (1), 177-188
DOI 10.1006/cimm.1993.1100

LAURITZSEN GF, WEISS S, BOGEN B (1993)
ANTITUMOR-ACTIVITY OF IDIOTYPE-SPECIFIC, MHC-RESTRICTED TH1 AND TH2 CLONES INVITRO AND INVIVO
Scand. J. Immunol., 37 (1), 77-85
DOI 10.1111/j.1365-3083.1993.tb01668.x

Publications 1992

BOGEN B, GLEDITSCH L, WEISS S, DEMBIC Z (1992)
WEAK POSITIVE SELECTION OF TRANSGENIC T-CELL RECEPTOR-BEARING THYMOCYTES - IMPORTANCE OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II, T-CELL RECEPTOR AND CD4 SURFACE-MOLECULE DENSITIES
Eur. J. Immunol., 22 (3), 703-709
DOI 10.1002/eji.1830220313

GLEDITSCH L, BOGEN B (1992)
A TCRA CONGENIC MOUSE - V-ALPHA EPITOPE EXPRESSION IS INFLUENCED BY BOTH TCRA HAPLOTYPES AND BACKGROUND GENES
Immunogenetics, 35 (3), 153-160

SNODGRASS HR, FISHER AM, BRUYNS E, BOGEN B (1992)
RESTRICTED ALPHA/BETA-RECEPTOR GENE USAGE OF IDIOTYPE-SPECIFIC MAJOR HISTOCOMPATIBILITY COMPLEX-RESTRICTED T-CELLS - SELECTION FOR CDR3-RELATED SEQUENCES
Eur. J. Immunol., 22 (8), 2169-2172
DOI 10.1002/eji.1830220832

Publications 1991

BOGEN B, WEISS S (1991)
A REARRANGED LAMBDA-2 LIGHT GENE CHAIN RETARDS BUT DOES NOT EXCLUDE-CHI AND LAMBDA-1 EXPRESSION
Eur. J. Immunol., 21 (10), 2391-2395
DOI 10.1002/eji.1830211015

LAURITZSEN GF, BOGEN B (1991)
IDIOTYPE-SPECIFIC, MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTED T-CELLS ARE OF BOTH TH1-TYPE AND TH2-TYPE
Scand. J. Immunol., 33 (6), 647-656
DOI 10.1111/j.1365-3083.1991.tb02537.x

WEISS S, BOGEN B (1991)
MHC CLASS-II-RESTRICTED PRESENTATION OF INTRACELLULAR ANTIGEN
Cell, 64 (4), 767-776
DOI 10.1016/0092-8674(91)90506-T

Publications 1990

BOGEN B, LAURITZSEN GF, WEISS S (1990)
A STIMULATORY MONOCLONAL-ANTIBODY DETECTING T-CELL RECEPTOR DIVERSITY AMONG IDIOTYPE-SPECIFIC, MAJOR HISTOCOMPATIBILITY COMPLEX-RESTRICTED T-CELL CLONES
Eur. J. Immunol., 20 (10), 2359-2362
DOI 10.1002/eji.1830201030

GLEDITSCH L, SNODGRASS R, BOGEN B (1990)
NO RECOMBINATIONS BETWEEN TCRA-V AND TCRA-C GENE SEGMENTS IN 669 BACKCROSS MICE
Immunogenetics, 32 (5), 297-303

Publications 1989

BOGEN B (1989)
MONOCLONAL-ANTIBODIES SPECIFIC FOR VARIABLE AND CONSTANT DOMAINS OF MURINE LAMBDA-CHAINS
Scand. J. Immunol., 29 (3), 273-279
DOI 10.1111/j.1365-3083.1989.tb01125.x

BOGEN B, LAMBRIS JD (1989)
MINIMUM LENGTH OF AN IDIOTYPIC PEPTIDE AND A MODEL FOR ITS BINDING TO A MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II MOLECULE
Embo J., 8 (7), 1947-1952
DOI 10.1002/j.1460-2075.1989.tb03599.x

WEISS S, BOGEN B (1989)
B-LYMPHOMA CELLS PROCESS AND PRESENT THEIR ENDOGENOUS IMMUNOGLOBULIN TO MAJOR HISTOCOMPATIBILITY COMPLEX-RESTRICTED T-CELLS
Proc. Natl. Acad. Sci. U. S. A., 86 (1), 282-286
DOI 10.1073/pnas.86.1.282

Publications 1986

BOGEN B, SNODGRASS R, BRIAND JP, HANNESTAD K (1986)
SYNTHETIC PEPTIDES AND BETA-CHAIN GENE REARRANGEMENTS REVEAL A DIVERSIFIED T-CELL REPERTOIRE FOR A LAMBDA-LIGHT CHAIN 3RD HYPERVARIABLE REGION
Eur. J. Immunol., 16 (11), 1379-1384
DOI 10.1002/eji.1830161111

Publications 1985

BOGEN B (1985)
DOMINANT SUPPRESSIVE EFFECT OF THE SILENT E-ALPHA-B ALLELE ON AN INVIVO T-HELPER CELL RESPONSE UNDER E-BETA-DE-ALPHA-D REGION-LINKED IMMUNE-RESPONSE GENE-CONTROL
Eur. J. Immunol., 15 (10), 1033-1037
DOI 10.1002/eji.1830151014

BOGEN B, JORGENSEN T, HANNESTAD K (1985)
T-HELPER CELL RECOGNITION OF IDIOTOPES ON LAMBDA-2 LIGHT-CHAINS OF M315 AND T952 - EVIDENCE FOR DEPENDENCE ON SOMATIC MUTATIONS IN THE 3RD HYPERVARIABLE REGION
Eur. J. Immunol., 15 (3), 278-281
DOI 10.1002/eji.1830150313

JORGENSEN T, BOGEN B, HANNESTAD K (1985)
H-2-LINKED IR GENES HAVE A STRIKING INFLUENCE ON THE IMMUNOGENICITY OF IDIOTOPES OF MYELOMA PROTEIN 315 FOR T-HELPER CELLS
Scand. J. Immunol., 21 (2), 183-187
DOI 10.1111/j.1365-3083.1985.tb01418.x

Publications 1984

BOGEN B (1984)
H-2 AND NON-H-2 GENES COMPLEMENT EACH OTHER FOR A CARRIER (IDIOTYPE)-SPECIFIC TH RESPONSE
Immunogenetics, 20 (4), 453-457
DOI 10.1007/BF00345619

BOGEN B (1984)
ANTIBODY-RESPONSES TO LAMBDA-1(J558) AND LAMBDA-2(315) LIGHT-CHAINS - SPECIFICITY AND GENETIC-REGULATION
Scand. J. Immunol., 20 (5), 413-424
DOI 10.1111/j.1365-3083.1984.tb01020.x

Bogen B (1984)
Murine Th and B lymphocyte recognition of isologous immunoglobulin
[B. Bogen], [Tromsø], 1 b. (flere pag.
BIBSYS 853020515

BOGEN B, HANNESTAD K (1984)
DETERMINANT-SPECIFIC REGULATION OF T-HELPER CELL RESPONSES TO MURINE LAMBDA-LIGHT CHAINS BY BOTH H-2 AND NON-H-2 GENES
Eur. J. Immunol., 14 (2), 158-163
DOI 10.1002/eji.1830140210

BOGEN B, HANNESTAD K (1984)
SPECIFICITY OF ANTIBODY AND HELPER T-CELL RESPONSES TO THE ISOLOGOUS MYELOMA PROTEIN-W3129 AND ITS SUBUNITS
Mol. Immunol., 21 (7), 653-661
DOI 10.1016/0161-5890(84)90051-8

Publications 1983

BOGEN B, JORGENSEN T, HANNESTAD K (1983)
RECOGNITION OF LAMBDA-1 AND LAMBDA-2 MURINE LIGHT-CHAINS BY CARRIER-SPECIFIC ISOLOGOUS T-HELPER CELLS - EFFECT OF L-H CHAIN ASSEMBLY
Eur. J. Immunol., 13 (5), 353-359
DOI 10.1002/eji.1830130502

JORGENSEN T, BOGEN B, HANNESTAD K (1983)
T-HELPER CELLS RECOGNIZE AN IDIOTOPE LOCATED ON PEPTIDE 88-114/117 OF THE LIGHT CHAIN VARIABLE DOMAIN OF AN ISOLOGOUS MYELOMA PROTEIN (315)
J. Exp. Med., 158 (6), 2183-2188
DOI 10.1084/jem.158.6.2183

Publications 1982

MARHAUG G, GAUDERNACK G, BOGEN B, HUSBY G (1982)
MONOCLONAL HYBRIDOMA ANTIBODIES TO HUMAN AMYLOID RELATED PROTEIN SAA
Clin. Exp. Immunol., 50 (2), 390-396