Bjarne Bogen
- Professor emeritus; MD, PhD
Publications 2024
Applying valency-based immuno-selection to generate broadly cross-reactive antibodies against influenza hemagglutinins
Nat Commun, 15 (1), 850
DOI 10.1038/s41467-024-44889-w, PubMed 38346952
IL-18-secreting multiantigen targeting CAR T cells eliminate antigen-low myeloma in an immunocompetent mouse model
Blood, 144 (2), 171-186
DOI 10.1182/blood.2023022293, PubMed 38579288
Publications 2023
3-O sulfation of syndecan-1 mediated by the sulfotransferase HS3ST3a1 enhances myeloma aggressiveness
Matrix Biol, 120, 60-75
DOI 10.1016/j.matbio.2023.05.005, PubMed 37201729
Tracking the cellular immune response from early premalignancy to active multiple myeloma in a new model
Eur J Immunol, 54 (1), e2350627
DOI 10.1002/eji.202350627, PubMed 37872778
EMD originates from hyaluronan-induced homophilic interactions of CD44 variant-expressing MM cells under shear stress
Blood Adv, 7 (4), 508-524
DOI 10.1182/bloodadvances.2022007291, PubMed 35930695
Preclinical Evaluation of a 64Cu-Based Theranostic Approach in a Murine Model of Multiple Myeloma
Pharmaceutics, 15 (7)
DOI 10.3390/pharmaceutics15071817, PubMed 37514004
Trimeric, APC-Targeted Subunit Vaccines Protect Mice against Seasonal and Pandemic Influenza
J Virol, 97 (2), e0169422
DOI 10.1128/jvi.01694-22, PubMed 36719241
Neuraminidase delivered as an APC-targeted DNA vaccine induces protective antibodies against influenza
Mol Ther, 31 (7), 2188-2205
DOI 10.1016/j.ymthe.2023.03.012, PubMed 36926694
Id-neoantigen vaccine induces therapeutic CD8+ T cells against multiple myeloma: H chain-loss escapees cause FLC MM
J Immunother Cancer, 11 (8)
DOI 10.1136/jitc-2023-006944, PubMed 37607769
Publications 2022
Neoantigen vaccine-induced CD4 T cells confer protective immunity in a mouse model of multiple myeloma through activation of CD8 T cells against non-vaccine, tumor-associated antigens
J Immunother Cancer, 10 (2)
DOI 10.1136/jitc-2021-003572, PubMed 35190376
Ballistic strength training in adults with cerebral palsy may increase rate of force development in plantar flexors, but transition to walking remains unclear: a case series
BMC Sports Sci Med Rehabil, 14 (1), 101
DOI 10.1186/s13102-022-00487-1, PubMed 35659348
Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses
Cell Rep, 39 (9), 110901
DOI 10.1016/j.celrep.2022.110901, PubMed 35649357
VSIG4-expressing tumor-associated macrophages impair anti-tumor immunity
Biochem Biophys Res Commun, 628, 18-24
DOI 10.1016/j.bbrc.2022.08.055, PubMed 36063598
Multiple Myeloma-Derived Extracellular Vesicles Modulate the Bone Marrow Immune Microenvironment
Front Immunol, 13, 909880
DOI 10.3389/fimmu.2022.909880, PubMed 35874665
Targeting Xcr1 on Dendritic Cells Rapidly Induce Th1-Associated Immune Responses That Contribute to Protection Against Influenza Infection
Front Immunol, 13, 752714
DOI 10.3389/fimmu.2022.752714, PubMed 35296089
Publications 2021
Pandemic Preparedness Against Influenza: DNA Vaccine for Rapid Relief
Front Immunol, 12, 747032
DOI 10.3389/fimmu.2021.747032, PubMed 34691056
APC-Targeted DNA Vaccination Against Reticulocyte-Binding Protein Homolog 5 Induces Plasmodium falciparum-Specific Neutralizing Antibodies and T Cell Responses
Front Immunol, 12, 720550
DOI 10.3389/fimmu.2021.720550, PubMed 34733274
ARHGAP45 controls naïve T- and B-cell entry into lymph nodes and T-cell progenitor thymus seeding
EMBO Rep, 22 (4), e52196
DOI 10.15252/embr.202052196, PubMed 33719206
Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses
Vaccine, 39 (11), 1583-1592
DOI 10.1016/j.vaccine.2021.02.012, PubMed 33612340
Intranasal delivery of a cDC1 targeted influenza vaccine with poly(I:C) enhances T cell responses and protects against influenza infection
Scand J Immunol, 95 (3), e13128
DOI 10.1111/sji.13128, PubMed 34923667
Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity
Cell Rep, 36 (6), 109525
DOI 10.1016/j.celrep.2021.109525, PubMed 34380042
Prevention of Bone Destruction by Mechanical Loading Is Not Enhanced by the Bruton's Tyrosine Kinase Inhibitor CC-292 in Myeloma Bone Disease
Int J Mol Sci, 22 (8)
DOI 10.3390/ijms22083840, PubMed 33917250
Publications 2020
The role of sweat in the composition of skin microbiome: lessons learned from patients with congenital insensitivity to pain with anhidrosis
J Eur Acad Dermatol Venereol, 34 (4), e183-e186
DOI 10.1111/jdv.16170, PubMed 31875978
A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza
Mol Ther Methods Clin Dev, 17, 378-392
DOI 10.1016/j.omtm.2020.01.007, PubMed 32128342
Targeting Antigens to Different Receptors on Conventional Type 1 Dendritic Cells Impacts the Immune Response
J Immunol, 205 (3), 661-673
DOI 10.4049/jimmunol.1901119, PubMed 32591401
Induction of Cross-Reactive and Protective Antibody Responses After DNA Vaccination With MHCII-Targeted Stem Domain From Influenza Hemagglutinin
Front Immunol, 11, 431
DOI 10.3389/fimmu.2020.00431, PubMed 32269566
CD4+ T-cell killing of multiple myeloma cells is mediated by resident bone marrow macrophages
Blood Adv, 4 (12), 2595-2605
DOI 10.1182/bloodadvances.2020001434, PubMed 32544236
PD-1 Blockade Reinvigorates Bone Marrow CD8+ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors
Clin Cancer Res, 26 (7), 1644-1655
DOI 10.1158/1078-0432.CCR-19-0267, PubMed 31941832
Author Correction: Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
Sci Rep, 10 (1), 5944
DOI 10.1038/s41598-020-62688-3, PubMed 32231213
Mechanical loading prevents bone destruction and exerts anti-tumor effects in the MOPC315.BM.Luc model of myeloma bone disease
Acta Biomater, 119, 247-258
DOI 10.1016/j.actbio.2020.10.041, PubMed 33130307
An Early Myeloma Bone Disease Model in Skeletally Mature Mice as a Platform for Biomaterial Characterization of the Extracellular Matrix
J Oncol, 2020, 3985315
DOI 10.1155/2020/3985315, PubMed 32684931
Publications 2019
Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules
NPJ Vaccines, 4, 9
DOI 10.1038/s41541-019-0101-0, PubMed 30775000
A role for IL-34 in osteolytic disease of multiple myeloma
Blood Adv, 3 (4), 541-551
DOI 10.1182/bloodadvances.2018020008, PubMed 30782613
CD4+ T cells indirectly kill tumor cells via induction of cytotoxic macrophages in mouse models
Cancer Immunol Immunother, 68 (11), 1865-1873
DOI 10.1007/s00262-019-02374-0, PubMed 31448380
Targeting of HA to chemokine receptors induces strong and cross-reactive T cell responses after DNA vaccination in pigs
Vaccine, 38 (6), 1280-1285
DOI 10.1016/j.vaccine.2019.11.084, PubMed 31836256
Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice
Front Immunol, 10, 1086
DOI 10.3389/fimmu.2019.01086, PubMed 31156636
B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells
Proc Natl Acad Sci U S A, 116 (51), 25850-25859
DOI 10.1073/pnas.1902836116, PubMed 31796587
Human Cysteine Cathepsins Degrade Immunoglobulin G In Vitro in a Predictable Manner
Int J Mol Sci, 20 (19)
DOI 10.3390/ijms20194843, PubMed 31569504
Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
Sci Rep, 9 (1), 1820
DOI 10.1038/s41598-018-38080-7, PubMed 30755656
Functional design of pH-responsive folate-targeted polymer-coated gold nanoparticles for drug delivery and in vivo therapy in breast cancer
Int J Nanomedicine, 14, 8285-8302
DOI 10.2147/IJN.S215142, PubMed 31802866
Needle-free delivery of DNA: Targeting of hemagglutinin to MHC class II molecules protects rhesus macaques against H1N1 influenza
Vaccine, 37 (6), 817-826
DOI 10.1016/j.vaccine.2018.12.049, PubMed 30638800
Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses
Front Immunol, 10, 1529
DOI 10.3389/fimmu.2019.01529, PubMed 31333661
Publications 2018
Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd
Sci Rep, 8 (1), 13319
DOI 10.1038/s41598-018-31510-6, PubMed 30190583
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
J Immunol, 200 (6), 2057-2066
DOI 10.4049/jimmunol.1701088, PubMed 29427414
The Magnitude and IgG Subclass of Antibodies Elicited by Targeted DNA Vaccines Are Influenced by Specificity for APC Surface Molecules
Immunohorizons, 2 (1), 38-53
DOI 10.4049/immunohorizons.1700038, PubMed 31022690
Tumor Killing by CD4+ T Cells Is Mediated via Induction of Inducible Nitric Oxide Synthase-Dependent Macrophage Cytotoxicity
Front Immunol, 9, 1684
DOI 10.3389/fimmu.2018.01684, PubMed 30083157
CD4+ T-cell-Mediated Rejection of MHC Class II-Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs
Cancer Res, 78 (16), 4573-4585
DOI 10.1158/0008-5472.CAN-17-2426, PubMed 29752262
Publications 2017
A DNA Vaccine That Targets Hemagglutinin to Antigen-Presenting Cells Protects Mice against H7 Influenza
J Virol, 91 (23)
DOI 10.1128/JVI.01340-17, PubMed 28931687
The anti-influenza M2e antibody response is promoted by XCR1 targeting in pig skin
Sci Rep, 7 (1), 7639
DOI 10.1038/s41598-017-07372-9, PubMed 28794452
Targeting Influenza Virus Hemagglutinin to Xcr1+ Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses
J Immunol, 198 (7), 2785-2795
DOI 10.4049/jimmunol.1601881, PubMed 28228559
In Silico Prediction Analysis of Idiotope-Driven T-B Cell Collaboration in Multiple Sclerosis
Front Immunol, 8, 1255
DOI 10.3389/fimmu.2017.01255, PubMed 29038659
Cyclized Oligopeptide Targeting LRP5/6-DKK1 Interaction Reduces the Growth of Tumor Burden in a Multiple Myeloma Mouse Model
Yonsei Med J, 58 (3), 505-513
DOI 10.3349/ymj.2017.58.3.505, PubMed 28332354
Autologous bone marrow Th cells can support multiple myeloma cell proliferation in vitro and in xenografted mice
Leukemia, 31 (10), 2114-2121
DOI 10.1038/leu.2017.69, PubMed 28232741
Publications 2016
Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity
Front Immunol, 7, 167
DOI 10.3389/fimmu.2016.00167, PubMed 27242780
Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery
Immunity, 45 (2), 305-18
DOI 10.1016/j.immuni.2016.07.019, PubMed 27533013
Systemic therapy with oncolytic myxoma virus cures established residual multiple myeloma in mice
Mol Ther Oncolytics, 3, 16032
DOI 10.1038/mto.2016.32, PubMed 27933316
Expanding the tools for identifying mononuclear phagocyte subsets in swine: Reagents to porcine CD11c and XCR1
Dev Comp Immunol, 65, 31-40
DOI 10.1016/j.dci.2016.06.015, PubMed 27345169
Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination
J Immunol, 197 (9), 3575-3585
DOI 10.4049/jimmunol.1600893, PubMed 27671110
Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species
Immunity, 45 (3), 669-684
DOI 10.1016/j.immuni.2016.08.015, PubMed 27637149
DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8(+) T Cell Responses, Enabling Faster Resolution of Influenza Disease
Front Immunol, 7, 321
DOI 10.3389/fimmu.2016.00321, PubMed 27602032
Ex Vivo Oncolytic Virotherapy with Myxoma Virus Arms Multiple Allogeneic Bone Marrow Transplant Leukocytes to Enhance Graft versus Tumor
Mol Ther Oncolytics, 4, 31-40
DOI 10.1016/j.omto.2016.12.002, PubMed 28345022
Adoptive Transfer of Tumor-Specific Th2 Cells Eradicates Tumors by Triggering an In Situ Inflammatory Immune Response
Cancer Res, 76 (23), 6864-6876
DOI 10.1158/0008-5472.CAN-16-1219, PubMed 27634753
Tumor-specific CD4+ T cells eradicate myeloma cells genetically deficient in MHC class II display
Oncotarget, 7 (41), 67175-67182
DOI 10.18632/oncotarget.11946, PubMed 27626487
Unlocking bat immunology: establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages
Sci Rep, 6, 38597
DOI 10.1038/srep38597, PubMed 27934903
Publications 2015
Targeting of nucleoprotein to chemokine receptors by DNA vaccination results in increased CD8(+)-mediated cross protection against influenza
Vaccine, 33 (49), 6988-96
DOI 10.1016/j.vaccine.2015.08.094, PubMed 26387432
Efficient vaccine against pandemic influenza: combining DNA vaccination and targeted delivery to MHC class II molecules
Expert Rev Vaccines, 14 (6), 805-14
DOI 10.1586/14760584.2015.1029919, PubMed 25818107
Polarizing T and B Cell Responses by APC-Targeted Subunit Vaccines
Front Immunol, 6, 367
DOI 10.3389/fimmu.2015.00367, PubMed 26257735
Interleukin-1 is required for cancer eradication mediated by tumor-specific Th1 cells
Oncoimmunology, 5 (1), e1039763
DOI 10.1080/2162402X.2015.1039763, PubMed 26942052
Idiotype-specific CD4(+) T cells eradicate disseminated myeloma
Leukemia, 30 (5), 1216-20
DOI 10.1038/leu.2015.278, PubMed 26449664
Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma
J Clin Invest, 125 (12), 4375-90
DOI 10.1172/JCI80325, PubMed 26517694
IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration
J Allergy Clin Immunol, 137 (5), 1487-1497.e6
DOI 10.1016/j.jaci.2015.10.018, PubMed 26653800
Autocrine amplification of immature myeloid cells by IL-6 in multiple myeloma-infiltrated bone marrow
Leukemia, 29 (9), 1882-90
DOI 10.1038/leu.2015.145, PubMed 26159051
Spleen tyrosine kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells
Haematologica, 101 (2), e59-62
DOI 10.3324/haematol.2015.135590, PubMed 26589914
Laser-assisted intradermal delivery of adjuvant-free vaccines targeting XCR1+ dendritic cells induces potent antitumoral responses
J Immunol, 194 (12), 5895-902
DOI 10.4049/jimmunol.1500564, PubMed 25941327
Tumors Escape CD4+ T-cell-Mediated Immunosurveillance by Impairing the Ability of Infiltrating Macrophages to Indirectly Present Tumor Antigens
Cancer Res, 75 (16), 3268-78
DOI 10.1158/0008-5472.CAN-14-3640, PubMed 26038231
Systemic Lupus Erythematosus: Molecular Mimicry between Anti-dsDNA CDR3 Idiotype, Microbial and Self Peptides-As Antigens for Th Cells
Front Immunol, 6, 382
DOI 10.3389/fimmu.2015.00382, PubMed 26284067
Publications 2014
Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells
J Immunol, 193 (4), 1622-35
DOI 10.4049/jimmunol.1401243, PubMed 25009205
Establishment of a murine graft-versus-myeloma model using allogeneic stem cell transplantation
PLoS One, 9 (11), e113764
DOI 10.1371/journal.pone.0113764, PubMed 25415267
Chronic lymphocytic leukemia cells express CD38 in response to Th1 cell-derived IFN-γ by a T-bet-dependent mechanism
J Immunol, 194 (2), 827-35
DOI 10.4049/jimmunol.1401350, PubMed 25505279
TLR3-responsive, XCR1+, CD141(BDCA-3)+/CD8α+-equivalent dendritic cells uncovered in healthy and simian immunodeficiency virus-infected rhesus macaques
J Immunol, 192 (10), 4697-708
DOI 10.4049/jimmunol.1302448, PubMed 24740505
Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8+ T-cell responses against influenza virus
Eur J Immunol, 45 (2), 624-35
DOI 10.1002/eji.201445080, PubMed 25410055
How Do CD4(+) T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?
Front Immunol, 5, 174
DOI 10.3389/fimmu.2014.00174, PubMed 24782871
Naive idiotope-specific B and T cells collaborate efficiently in the absence of dendritic cells
J Immunol, 192 (9), 4174-83
DOI 10.4049/jimmunol.1302359, PubMed 24706724
DNA vaccines: MHC II-targeted vaccine protein produced by transfected muscle fibres induces a local inflammatory cell infiltrate in mice
PLoS One, 9 (10), e108069
DOI 10.1371/journal.pone.0108069, PubMed 25299691
Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice
J Transl Med, 12, 207
DOI 10.1186/1479-5876-12-207, PubMed 25059102
Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model
Blood Cancer J, 4 (6), e217
DOI 10.1038/bcj.2014.37, PubMed 24927406
Limitations of bystander killing in Th1/M1 immune responses against a secreted tumor antigen
Oncoimmunology, 3 (9), e954953
DOI 10.4161/21624011.2014.954953, PubMed 25941607
Indirect CD4+ T-cell-mediated elimination of MHC II(NEG) tumor cells is spatially restricted and fails to prevent escape of antigen-negative cells
Eur J Immunol, 44 (9), 2625-37
DOI 10.1002/eji.201444659, PubMed 24846412
Eosinophils and megakaryocytes support the early growth of murine MOPC315 myeloma cells in their bone marrow niches
PLoS One, 9 (10), e109018
DOI 10.1371/journal.pone.0109018, PubMed 25272036
Increased generation of HIV-1 gp120-reactive CD8+ T cells by a DNA vaccine construct encoding the chemokine CCL3
PLoS One, 9 (8), e104814
DOI 10.1371/journal.pone.0104814, PubMed 25122197
Idiotype-specific Th cells support oligoclonal expansion of anti-dsDNA B cells in mice with lupus
J Immunol, 193 (6), 2691-8
DOI 10.4049/jimmunol.1400640, PubMed 25127856
Publications 2013
A public T cell receptor recognized by a monoclonal antibody specific for the D-J junction of the β-chain
Scand J Immunol, 78 (4), 345-51
DOI 10.1111/sji.12098, PubMed 23841814
DNA vaccine that targets hemagglutinin to MHC class II molecules rapidly induces antibody-mediated protection against influenza
J Immunol, 191 (6), 3221-31
DOI 10.4049/jimmunol.1300504, PubMed 23956431
The specificity of targeted vaccines for APC surface molecules influences the immune response phenotype
PLoS One, 8 (11), e80008
DOI 10.1371/journal.pone.0080008, PubMed 24244595
Chaperone-assisted thermostability engineering of a soluble T cell receptor using phage display
Sci Rep, 3, 1162
DOI 10.1038/srep01162, PubMed 23362461
Tumor cells loaded with α-galactosylceramide promote therapeutic NKT-dependent anti-tumor immunity in multiple myeloma
Immunol Lett, 156 (1-2), 132-9
DOI 10.1016/j.imlet.2013.10.002, PubMed 24148970
B-cell tolerance to the B-cell receptor variable regions
Eur J Immunol, 43 (10), 2577-87
DOI 10.1002/eji.201243203, PubMed 23839948
Molecular profiling of tumor-specific TH1 cells activated in vivo
Oncoimmunology, 2 (5), e24383
DOI 10.4161/onci.24383, PubMed 23762808
Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells
Cell Rep, 4 (3), 566-77
DOI 10.1016/j.celrep.2013.07.011, PubMed 23933259
Publications 2012
SH2D2A modulates T cell mediated protection to a B cell derived tumor in transgenic mice
PLoS One, 7 (10), e48239
DOI 10.1371/journal.pone.0048239, PubMed 23144743
Targeted DNA vaccines for enhanced induction of idiotype-specific B and T cells
Front Oncol, 2, 154
DOI 10.3389/fonc.2012.00154, PubMed 23115759
The heat shock transcription factor 1 as a potential new therapeutic target in multiple myeloma
Br J Haematol, 160 (4), 465-76
DOI 10.1111/bjh.12164, PubMed 23252346
A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease
PLoS One, 7 (12), e51892
DOI 10.1371/journal.pone.0051892, PubMed 23284805
A model for cancer-suppressive inflammation
Oncoimmunology, 1 (7), 1146-1155
DOI 10.4161/onci.21542, PubMed 23170261
Fingolimod blocks immunosurveillance of myeloma and B-cell lymphoma resulting in cancer development in mice
Blood, 119 (9), 2176-7
DOI 10.1182/blood-2011-10-388892, PubMed 22383793
DeltaPhage--a novel helper phage for high-valence pIX phagemid display
Nucleic Acids Res, 40 (16), e120
DOI 10.1093/nar/gks341, PubMed 22539265
CD40/APC-specific antibodies with three T-cell epitopes loaded in the constant domains induce CD4+ T-cell responses
Protein Eng Des Sel, 25 (3), 89-96
DOI 10.1093/protein/gzr063, PubMed 22233931
Non-invasive imaging provides spatiotemporal information on disease progression and response to therapy in a murine model of multiple myeloma
PLoS One, 7 (12), e52398
DOI 10.1371/journal.pone.0052398, PubMed 23300660
Heterodimeric barnase-barstar vaccine molecules: influence of one versus two targeting units specific for antigen presenting cells
PLoS One, 7 (9), e45393
DOI 10.1371/journal.pone.0045393, PubMed 23028981
Generation of antibody-producing hybridomas following one single immunization with a targeted DNA vaccine
Scand J Immunol, 75 (4), 379-88
DOI 10.1111/j.1365-3083.2011.02639.x, PubMed 21955209
Publications 2011
Lymphoma invisibility-vaccination-attack?
Blood, 117 (5), 1437-8
DOI 10.1182/blood-2010-11-318469, PubMed 21292780
Welcome to the 40th Scandinavian Society for Immunology meeting at Geilo, Norway
Scand. J. Immunol., 73 (4), 267
DOI 10.1111/j.1365-3083.2011.02509.x
Is secretion of tumour-specific antigen important for cancer eradication by CD4(+) T cells?--Implications for cancer immunotherapy by adoptive T cell transfer
Scand J Immunol, 73 (6), 527-30
DOI 10.1111/j.1365-3083.2011.02558.x, PubMed 21388431
Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α+ type
J Immunol, 187 (9), 4411-5
DOI 10.4049/jimmunol.1101717, PubMed 21948982
Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model
BMC Cancer, 11, 301
DOI 10.1186/1471-2407-11-301, PubMed 21767374
Targeted idiotype-fusion DNA vaccines for human multiple myeloma: preclinical testing
Eur J Haematol, 86 (5), 385-95
DOI 10.1111/j.1600-0609.2011.01590.x, PubMed 21332794
Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer
Nat Commun, 2, 240
DOI 10.1038/ncomms1239, PubMed 21407206
Expanding the versatility of phage display I: efficient display of peptide-tags on protein VII of the filamentous phage
PLoS One, 6 (2), e14702
DOI 10.1371/journal.pone.0014702, PubMed 21390217
Expanding the versatility of phage display II: improved affinity selection of folded domains on protein VII and IX of the filamentous phage
PLoS One, 6 (2), e17433
DOI 10.1371/journal.pone.0017433, PubMed 21390283
Publications 2010
Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA
BMC Biotechnol, 10, 8
DOI 10.1186/1472-6750-10-8, PubMed 20128915
The cellular mechanism by which complementary Id+ and anti-Id antibodies communicate: T cells integrated into idiotypic regulation
Immunol Cell Biol, 88 (5), 515-22
DOI 10.1038/icb.2009.118, PubMed 20066000
Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins
BMC Biotechnol, 10, 61
DOI 10.1186/1472-6750-10-61, PubMed 20735812
Human chemokine MIP1α increases efficiency of targeted DNA fusion vaccines
Vaccine, 29 (2), 191-9
DOI 10.1016/j.vaccine.2010.10.057, PubMed 21055498
Publications 2009
Review: to what extent are T cells tolerant to immunoglobulin variable regions?
Scand J Immunol, 70 (6), 526-30
DOI 10.1111/j.1365-3083.2009.02340.x, PubMed 19906193
Secretion of tumor-specific antigen by myeloma cells is required for cancer immunosurveillance by CD4+ T cells
Cancer Res, 69 (14), 5901-7
DOI 10.1158/0008-5472.CAN-08-4816, PubMed 19567679
The idiotype connection: linking infection and multiple sclerosis
Trends Immunol, 31 (2), 56-62
DOI 10.1016/j.it.2009.11.001, PubMed 19962346
Tracking early autoimmune disease by bioluminescent imaging of NF-kappaB activation reveals pathology in multiple organ systems
Am J Pathol, 174 (4), 1358-67
DOI 10.2353/ajpath.2009.080700, PubMed 19286564
Publications 2008
Processing of an antigenic sequence from IgG constant domains for presentation by MHC class II
J Immunol, 181 (10), 7062-72
DOI 10.4049/jimmunol.181.10.7062, PubMed 18981126
Recombinant antibodies for delivery of antigen: a single loop between beta-strands in the constant region can accommodate long, complex and tandem T cell epitopes
Int Immunol, 20 (3), 295-306
DOI 10.1093/intimm/dxm141, PubMed 18252695
Publications 2007
Immunologi
Universitetsforl., Oslo (2. utg.), 334 s.
BIBSYS 070820953, ISBN 978-82-15-01093-9
Chemokine-idiotype fusion DNA vaccines are potentiated by bivalency and xenogeneic sequences
Blood, 110 (6), 1797-805
DOI 10.1182/blood-2006-06-032938, PubMed 17540847
A VH4-34+ myeloma protein with weak autoreactivity
Haematologica, 92 (5), 690-3
DOI 10.3324/haematol.10850, PubMed 17488696
T cells from multiple sclerosis patients recognize multiple epitopes on Self-IgG
Scand J Immunol, 66 (4), 393-401
DOI 10.1111/j.1365-3083.2007.01955.x, PubMed 17850583
Expression of SH2D2A in T-cells is regulated both at the transcriptional and translational level
Mol Immunol, 45 (8), 2380-90
DOI 10.1016/j.molimm.2007.11.005, PubMed 18160104
Functional phage display of two murine alpha/beta T-cell receptors is strongly dependent on fusion format, mode and periplasmic folding assistance
Protein Eng Des Sel, 20 (9), 461-72
DOI 10.1093/protein/gzm044, PubMed 17925331
Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells
Scand J Immunol, 65 (3), 213-20
DOI 10.1111/j.1365-3083.2006.01881.x, PubMed 17309775
Delivery of antigen to CD40 induces protective immune responses against tumors
J Immunol, 178 (7), 4169-76
DOI 10.4049/jimmunol.178.7.4169, PubMed 17371973
Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates
Vaccine, 25 (24), 4723-34
DOI 10.1016/j.vaccine.2007.04.004, PubMed 17499405
Lymphomas can develop from B cells chronically helped by idiotype-specific T cells
J Exp Med, 204 (5), 1181-91
DOI 10.1084/jem.20061220, PubMed 17485509
Publications 2006
Idiotype-specific immunotherapy in multiple myeloma: suggestions for future directions of research
Haematologica, 91 (7), 941-8
PubMed 16818282
DNA vaccines increase immunogenicity of idiotypic tumor antigen by targeting novel fusion proteins to antigen-presenting cells
Mol Ther, 13 (4), 776-85
DOI 10.1016/j.ymthe.2005.10.019, PubMed 16414309
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
EMBO J, 25 (4), 683-92
DOI 10.1038/sj.emboj.7600991, PubMed 16467847
[DNA--the future in vaccine technology?]
Tidsskr Nor Laegeforen, 126 (22), 2964-8
PubMed 17117196
Publications 2005
Primary antitumor immune response mediated by CD4+ T cells
Immunity, 22 (3), 371-83
DOI 10.1016/j.immuni.2005.02.003, PubMed 15780993
Cerebrospinal fluid T cell clones from patients with multiple sclerosis: recognition of idiotopes on monoclonal IgG secreted by autologous cerebrospinal fluid B cells
Eur J Immunol, 35 (6), 1786-94
DOI 10.1002/eji.200425417, PubMed 15864781
Systemic autoimmune disease caused by autoreactive B cells that receive chronic help from Ig V region-specific T cells
J Immunol, 175 (4), 2391-400
DOI 10.4049/jimmunol.175.4.2391, PubMed 16081810
Induction of central T cell tolerance: recombinant antibodies deliver peptides for deletion of antigen-specific (CD4+)8+ thymocytes
Eur J Immunol, 35 (11), 3142-52
DOI 10.1002/eji.200425947, PubMed 16184515
Publications 2004
Immunotherapy in multiple myeloma: Id-specific strategies suggested by studies in animal models
Cancer Immunol Immunother, 53 (9), 759-69
DOI 10.1007/s00262-004-0504-1, PubMed 15088126
Anti-class II antibodies, but not cytotoxic T-lymphocyte antigen 4-immunoglobulin hybrid molecules, prevent rejection of major histocompatibility complex class II-negative myeloma in T-cell receptor-transgenic mice
Scand J Immunol, 60 (1-2), 143-52
DOI 10.1111/j.0300-9475.2004.01435.x, PubMed 15238083
Tumour necrosis factor receptor superfamily member 6 gene mutation detection by denaturing high-performance liquid chromatography
Scand J Immunol, 59 (5), 496-503
DOI 10.1111/j.0300-9475.2004.01422.x, PubMed 15140060
CD4+ T cells kill Id+ B-lymphoma cells: FasLigand-Fas interaction is dominant in vitro but is redundant in vivo
Cancer Immunol Immunother, 53 (12), 1135-45
DOI 10.1007/s00262-004-0538-4, PubMed 15696611
MHC-restricted Ig V region-driven T-B lymphocyte collaboration: B cell receptor ligation facilitates switch to IgG production
J Immunol, 172 (12), 7476-84
DOI 10.4049/jimmunol.172.12.7476, PubMed 15187126
Genetic fusions with viral chemokines target delivery of nonimmunogenic antigen to trigger antitumor immunity independent of chemotaxis
J Leukoc Biol, 76 (1), 77-85
DOI 10.1189/jlb.1003481, PubMed 15075363
Monoclonal antibodies produced by muscle after plasmid injection and electroporation
Mol Ther, 9 (3), 328-36
DOI 10.1016/j.ymthe.2003.12.007, PubMed 15006599
Human CD14 is an efficient target for recombinant immunoglobulin vaccine constructs that deliver T cell epitopes
J Leukoc Biol, 77 (3), 303-10
DOI 10.1189/jlb.0804480, PubMed 15576418
Publications 2003
Liver metastasis of cancer facilitated by chemokine receptor CCR6
Scand J Immunol, 57 (6), 534-44
DOI 10.1046/j.1365-3083.2003.01263.x, PubMed 12791091
Therapeutic effect of idiotype-specific CD4+ T cells against B-cell lymphoma in the absence of anti-idiotypic antibodies
Blood, 102 (2), 605-12
DOI 10.1182/blood-2002-11-3381, PubMed 12649166
Antibody-mediated delivery of antigen to chemokine receptors on antigen-presenting cells results in enhanced CD4+ T cell responses
Eur J Immunol, 33 (11), 3101-8
DOI 10.1002/eji.200324299, PubMed 14579278
Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target
J Immunol, 171 (1), 32-6
DOI 10.4049/jimmunol.171.1.32, PubMed 12816980
Publications 2002
A mouse model for immunotherapy of myeloma
Hematol J, 3 (5), 224-9
DOI 10.1038/sj.thj.6200183, PubMed 12391539
Troybodies and pepbodies
Biochem Soc Trans, 30 (4), 500-6
DOI 10.1042/bst0300500, PubMed 12196123
Efficient delivery of T cell epitopes to APC by use of MHC class II-specific Troybodies
J Immunol, 168 (5), 2154-62
DOI 10.4049/jimmunol.168.5.2154, PubMed 11859101
A mouse C kappa-specific T cell clone indicates that DC-SIGN is an efficient target for antibody-mediated delivery of T cell epitopes for MHC class II presentation
Int Immunol, 14 (12), 1423-30
DOI 10.1093/intimm/dxf110, PubMed 12456590
Publications 2001
Phagocytic dendritic cells from myelomas activate tumor-specific T cells at a single cell level
Blood, 97 (9), 2808-14
DOI 10.1182/blood.v97.9.2808, PubMed 11313275
"Troy-bodies": recombinant antibodies that target T cell epitopes to antigen presenting cells
Int Rev Immunol, 20 (5), 647-73
DOI 10.3109/08830180109045583, PubMed 11890617
'Troy-bodies': antibodies as vector proteins for T cell epitopes
Biomol Eng, 18 (3), 109-16
DOI 10.1016/s1389-0344(01)00091-0, PubMed 11566602
T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation
J Exp Med, 193 (11), 1239-46
DOI 10.1084/jem.193.11.1239, PubMed 11390431
The principle of delivery of T cell epitopes to antigen-presenting cells applied to peptides from influenza virus, ovalbumin, and hen egg lysozyme: implications for peptide vaccination
Proc Natl Acad Sci U S A, 98 (18), 10296-301
DOI 10.1073/pnas.181336898, PubMed 11517321
Publications 2000
Immunologi
Universitetsforl., [Oslo], 295 s.
BIBSYS 991347749, ISBN 82-518-3875-4
Deletion of idiotype (Id)-specific T cells in multiple myeloma
Acta Oncol, 39 (7), 783-8
DOI 10.1080/028418600750063505, PubMed 11145433
Dendritic cells purified from myeloma are primed with tumor-specific antigen (idiotype) and activate CD4+ T cells
Proc Natl Acad Sci U S A, 97 (6), 2697-702
DOI 10.1073/pnas.050579897, PubMed 10706628
Recombinant antibodies as carrier proteins for sub-unit vaccines: influence of mode of fusion on protein production and T-cell activation
J Immunol Methods, 245 (1-2), 119-31
DOI 10.1016/s0022-1759(00)00274-x, PubMed 11042289
Publications 1999
The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors
J Exp Med, 190 (7), 1025-32
DOI 10.1084/jem.190.7.1025, PubMed 10510092
Antibodies engineered with IgD specificity efficiently deliver integrated T-cell epitopes for antigen presentation by B cells
Nat Biotechnol, 17 (7), 670-5
DOI 10.1038/10883, PubMed 10404160
Resting small B cells present endogenous immunoglobulin variable-region determinants to idiotope-specific CD4(+) T cells in vivo
Eur J Immunol, 29 (12), 4043-52
DOI 10.1002/(SICI)1521-4141(199912)29:12<4043::AID-IMMU4043>3.0.CO;2-E, PubMed 10602015
Publications 1998
[Kaspase or caspase?]
Tidsskr Nor Laegeforen, 118 (30), 4790
PubMed 9914770
Transient overexpression of CD4 enhances allelic exclusion of T-cell receptor (TCR) alpha chains and promotes positive selection of class II-restricted TCR-transgenic thymocytes
Mol Immunol, 35 (1), 23-38
DOI 10.1016/s0161-5890(98)00004-2, PubMed 9683261
Expression level of a transgenic lambda2 chain results in isotype exclusion and commitment to B1 cells
Eur J Immunol, 28 (8), 2289-99
DOI 10.1002/(SICI)1521-4141(199808)28:08<2289::AID-IMMU2289>3.0.CO;2-Y, PubMed 9710207
Clonal deletion of thymocytes as a tumor escape mechanism
Int J Cancer, 78 (2), 216-22
DOI 10.1002/(sici)1097-0215(19981005)78:2<216::aid-ijc16>3.0.co;2-8, PubMed 9754655
Thymic skewing of the CD4/CD8 ratio maps with the T-cell receptor alpha-chain locus
Curr Biol, 8 (12), 701-4
DOI 10.1016/s0960-9822(98)70276-3, PubMed 9637921
Publications 1997
[University medicine in Silicon Valley]
Tidsskr Nor Laegeforen, 117 (11), 1641-2
PubMed 9198951
Immunoglobulin as a vehicle for foreign antigenic peptides immunogenic to T cells
Mol Immunol, 34 (16-17), 1167-76
DOI 10.1016/s0161-5890(97)00143-0, PubMed 9566764
Rationale for adjuvant idiotypic vaccination after high-dose therapy for multiple myeloma
Biol Blood Marrow Transplant, 3 (3), 157-63
PubMed 9310193
Publications 1996
Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptor
Eur J Immunol, 26 (12), 2876-84
DOI 10.1002/eji.1830261211, PubMed 8977280
Peripheral T cell tolerance as a tumor escape mechanism: deletion of CD4+ T cells specific for a monoclonal immunoglobulin idiotype secreted by a plasmacytoma
Eur J Immunol, 26 (11), 2671-9
DOI 10.1002/eji.1830261119, PubMed 8921954
V lambda-light chain genes reconstitute immune responses to defined carbohydrate antigens or haptens by utilizing different VH genes
Mol Immunol, 33 (17-18), 1359-68
DOI 10.1016/s0161-5890(96)00095-8, PubMed 9171895
T cells with two Tcrbeta chains and reactivity to both MHC/idiotypic peptide and superantigen
Cell Immunol, 170 (2), 283-90
DOI 10.1006/cimm.1996.0162, PubMed 8660828
Publications 1995
Naive CD4+ T cells confer idiotype-specific tumor resistance in the absence of antibodies
Eur J Immunol, 25 (11), 3079-86
DOI 10.1002/eji.1830251114, PubMed 7489746
Peptide phage libraries can be an efficient tool for identifying antibody ligands for polyclonal antisera
Clin Exp Immunol, 102 (2), 438-42
DOI 10.1111/j.1365-2249.1995.tb03802.x, PubMed 7586703
Preferential positive selection of T lymphocytes which express two different TCR alpha chains, an endogenous and a transgenic
Scand J Immunol, 42 (6), 651-61
DOI 10.1111/j.1365-3083.1995.tb03708.x, PubMed 8552989
Publications 1994
Thymic selection of immunoglobulin idiotype specific T-cells
Thymus, 22 (3), 141-52
PubMed 7940642
Naive idiotype-specific CD4+ T cells and immunosurveillance of B-cell tumors
Proc Natl Acad Sci U S A, 91 (12), 5700-4
DOI 10.1073/pnas.91.12.5700, PubMed 7911244
Ca2+ mobilization in physiologically stimulated single T cells gradually increases with peptide concentration (analog signaling)
Eur J Immunol, 24 (4), 851-8
DOI 10.1002/eji.1830240412, PubMed 8149956
Publications 1993
Clonal deletion of specific thymocytes by an immunoglobulin idiotype
EMBO J, 12 (1), 357-63
DOI 10.1002/j.1460-2075.1993.tb05664.x, PubMed 8428591
T-cell receptor alpha haplotype influences V alpha epitope expression on both cortisone-resistant thymocytes and lymph node T cells
Scand J Immunol, 37 (6), 690-5
DOI 10.1111/j.1365-3083.1993.tb01685.x, PubMed 7686302
Processing and presentation of idiotypes to MHC-restricted T cells
Int Rev Immunol, 10 (4), 337-55
DOI 10.3109/08830189309061709, PubMed 8294847
The role of idiotype-specific, CD4+ T cells in tumor resistance against major histocompatibility complex class II molecule negative plasmacytoma cells
Cell Immunol, 148 (1), 177-88
DOI 10.1006/cimm.1993.1100, PubMed 8098665
Anti-tumour activity of idiotype-specific, MHC-restricted Th1 and Th2 clones in vitro and in vivo
Scand J Immunol, 37 (1), 77-85
DOI 10.1111/j.1365-3083.1993.tb01668.x, PubMed 8418475
Publications 1992
Weak positive selection of transgenic T cell receptor-bearing thymocytes: importance of major histocompatibility complex class II, T cell receptor and CD4 surface molecule densities
Eur J Immunol, 22 (3), 703-9
DOI 10.1002/eji.1830220313, PubMed 1547816
A Tcra congenic mouse: V alpha epitope expression is influenced by both Tcra haplotypes and background genes
Immunogenetics, 35 (3), 153-60
DOI 10.1007/BF00185108, PubMed 1371498
Restricted alpha/beta receptor gene usage of idiotype-specific major histocompatibility complex-restricted T cells: selection for CDR3-related sequences
Eur J Immunol, 22 (8), 2169-72
DOI 10.1002/eji.1830220832, PubMed 1379189
Publications 1991
A rearranged lambda 2 light gene chain retards but does not exclude kappa and lambda 1 expression
Eur J Immunol, 21 (10), 2391-5
DOI 10.1002/eji.1830211015, PubMed 1915552
Idiotype-specific, major histocompatibility complex restricted T cells are of both Th1 and Th2 type
Scand J Immunol, 33 (6), 647-56
DOI 10.1111/j.1365-3083.1991.tb02537.x, PubMed 1675480
MHC class II-restricted presentation of intracellular antigen
Cell, 64 (4), 767-76
DOI 10.1016/0092-8674(91)90506-t, PubMed 1847667
Publications 1990
A stimulatory monoclonal antibody detecting T cell receptor diversity among idiotype-specific, major histocompatibility complex-restricted T cell clones
Eur J Immunol, 20 (10), 2359-62
DOI 10.1002/eji.1830201030, PubMed 1700755
No recombinations between Tcra-V and Tcra-C gene segments in 669 backcross mice
Immunogenetics, 32 (5), 297-303
DOI 10.1007/BF00211642, PubMed 1979062
Publications 1989
Monoclonal antibodies specific for variable and constant domains of murine lambda chains
Scand J Immunol, 29 (3), 273-9
DOI 10.1111/j.1365-3083.1989.tb01125.x, PubMed 2497510
Minimum length of an idiotypic peptide and a model for its binding to a major histocompatibility complex class II molecule
EMBO J, 8 (7), 1947-52
DOI 10.1002/j.1460-2075.1989.tb03599.x, PubMed 2792076
B-lymphoma cells process and present their endogenous immunoglobulin to major histocompatibility complex-restricted T cells
Proc Natl Acad Sci U S A, 86 (1), 282-6
DOI 10.1073/pnas.86.1.282, PubMed 2492101
Publications 1988
B lymphoma cells process and present their endogenous IG: implications for network theory
Adv Exp Med Biol, 237, 877-82
DOI 10.1007/978-1-4684-5535-9_131, PubMed 3267071
Publications 1986
Idiotope-specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules
Eur J Immunol, 16 (11), 1373-8
DOI 10.1002/eji.1830161110, PubMed 3096740
Synthetic peptides and beta-chain gene rearrangements reveal a diversified T cell repertoire for a lambda light chain third hypervariable region
Eur J Immunol, 16 (11), 1379-84
DOI 10.1002/eji.1830161111, PubMed 3096741
Publications 1985
Dominant suppressive effect of the silent Eb alpha allele on an in vivo T helper cell response under Ed beta Ed alpha region-linked immune response gene control
Eur J Immunol, 15 (10), 1033-7
DOI 10.1002/eji.1830151014, PubMed 2932337
T helper cell recognition of idiotopes on lambda 2 light chains of M315 and T952: evidence for dependence on somatic mutations in the third hypervariable region
Eur J Immunol, 15 (3), 278-81
DOI 10.1002/eji.1830150313, PubMed 2579823
H-2-linked Ir genes have a striking influence on the immunogenicity of idiotopes of myeloma protein 315 for T helper cells
Scand J Immunol, 21 (2), 183-7
DOI 10.1111/j.1365-3083.1985.tb01418.x, PubMed 3156401
Publications 1984
Antibody responses to lambda 1J558 and lambda 2315 light chains. Specificity and genetic regulation
Scand J Immunol, 20 (5), 413-24
DOI 10.1111/j.1365-3083.1984.tb01020.x, PubMed 6209791
H-2 and non-H-2 genes complement each other for a carrier (idiotype)-specific Th response
Immunogenetics, 20 (4), 453-7
DOI 10.1007/BF00345619, PubMed 6237990
Murine Th and B lymphocyte recognition of isologous immunoglobulin
[B. Bogen], [Tromsø], 1 b. (flere pag.
BIBSYS 853020515
Determinant-specific regulation of T helper cell responses to murine lambda light chains by both H-2 and non-H-2 genes
Eur J Immunol, 14 (2), 158-63
DOI 10.1002/eji.1830140210, PubMed 6199213
Specificity of antibody and helper T-cell responses to the isologous myeloma protein W3129 and its subunits
Mol Immunol, 21 (7), 653-61
DOI 10.1016/0161-5890(84)90051-8, PubMed 6205254
Publications 1983
Recognition of lambda 1 and lambda 2 murine light chains by carrier-specific isologous T helper cells; effect of L-H chain assembly
Eur J Immunol, 13 (5), 353-9
DOI 10.1002/eji.1830130502, PubMed 6189725
T helper cells recognize an idiotope located on peptide 88-114/117 of the light chain variable domain of an isologous myeloma protein (315)
J Exp Med, 158 (6), 2183-8
DOI 10.1084/jem.158.6.2183, PubMed 6227679
Publications 1982
Monoclonal hybridoma antibodies to human amyloid related protein SAA
Clin Exp Immunol, 50 (2), 390-6
PubMed 7151332
Publications 1981
[Acquired idiopathic hypogammaglobulinemia. A patient protocol]
Tidsskr Nor Laegeforen, 101 (7), 459-61
PubMed 7209936