Even Fossum

  • Researcher; PhD
  • +47 23 07 30 45
 

Publications 2021

He L, Valignat MP, Zhang LC, Gelard L, Zhang FH, Le Guen V, Audebert S, Camoin L, Fossum E, Bogen B, Wang H, Henri S, Roncagalli R, Theodoly O, Liang YM, Malissen M, Malissen B (2021)
ARHGAP45 controls naive T- and B- cell entry into lymph nodes and T-cell progenitor thymus seeding
EMBO Rep., 22 (4), e52196

Publications 2020

Braathen R, Spång HCL, Hinke DM, Blazevski J, Bobic S, Fossum E, Bogen B (2020)
A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza
Mol Ther Methods Clin Dev, 17, 378-392
DOI 10.1016/j.omtm.2020.01.007, PubMed 32128342

Fossum E, Tesfaye DY, Bobic S, Gudjonsson A, Braathen R, Lahoud MH, Caminschi I, Bogen B (2020)
Targeting Antigens to Different Receptors on Conventional Type 1 Dendritic Cells Impacts the Immune Response
J Immunol, 205 (3), 661-673
DOI 10.4049/jimmunol.1901119, PubMed 32591401

Lysén A, Braathen R, Gudjonsson A, Tesfaye DY, Bogen B, Fossum E (2020)
Author Correction: Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
Sci Rep, 10 (1), 5944
DOI 10.1038/s41598-020-62688-3, PubMed 32231213

Publications 2019

Grodeland G, Fossum E, Bogen B (2019)
Targeting of HA to chemokine receptors induces strong and cross-reactive T cell responses after DNA vaccination in pigs
Vaccine, 38 (6), 1280-1285
DOI 10.1016/j.vaccine.2019.11.084, PubMed 31836256

Gudjonsson A, Andersen TK, Sundvold-Gjerstad V, Bogen B, Fossum E (2019)
Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice
Front Immunol, 10, 1086
DOI 10.3389/fimmu.2019.01086, PubMed 31156636

Lysén A, Braathen R, Gudjonsson A, Tesfaye DY, Bogen B, Fossum E (2019)
Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
Sci Rep, 9 (1), 1820
DOI 10.1038/s41598-018-38080-7, PubMed 30755656

Tesfaye DY, Gudjonsson A, Bogen B, Fossum E (2019)
Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses
Front Immunol, 10, 1529
DOI 10.3389/fimmu.2019.01529, PubMed 31333661

Publications 2018

Braathen R, Spång HCL, Lindeberg MM, Fossum E, Grødeland G, Fredriksen AB, Bogen B (2018)
The Magnitude and IgG Subclass of Antibodies Elicited by Targeted DNA Vaccines Are Influenced by Specificity for APC Surface Molecules
Immunohorizons, 2 (1), 38-53
DOI 10.4049/immunohorizons.1700038, PubMed 31022690

Publications 2017

Deloizy C, Fossum E, Barnier-Quer C, Urien C, Chrun T, Duval A, Codjovi M, Bouguyon E, Maisonnasse P, Hervé PL, Barc C, Boulesteix O, Pezant J, Chevalier C, Collin N, Dalod M, Bogen B, Bertho N, Schwartz-Cornil I (2017)
The anti-influenza M2e antibody response is promoted by XCR1 targeting in pig skin
Sci Rep, 7 (1), 7639
DOI 10.1038/s41598-017-07372-9, PubMed 28794452

Gudjonsson A, Lysén A, Balan S, Sundvold-Gjerstad V, Arnold-Schrauf C, Richter L, Bækkevold ES, Dalod M, Bogen B, Fossum E (2017)
Targeting Influenza Virus Hemagglutinin to Xcr1+ Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses
J Immunol, 198 (7), 2785-2795
DOI 10.4049/jimmunol.1601881, PubMed 28228559

Publications 2016

Ardouin L, Luche H, Chelbi R, Carpentier S, Shawket A, Montanana Sanchis F, Santa Maria C, Grenot P, Alexandre Y, Grégoire C, Fries A, Vu Manh TP, Tamoutounour S, Crozat K, Tomasello E, Jorquera A, Fossum E, Bogen B, Azukizawa H, Bajenoff M, Henri S, Dalod M, Malissen B (2016)
Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery
Immunity, 45 (2), 305-18
DOI 10.1016/j.immuni.2016.07.019, PubMed 27533013

Deloizy C, Bouguyon E, Fossum E, Sebo P, Osicka R, Bole A, Pierres M, Biacchesi S, Dalod M, Bogen B, Bertho N, Schwartz-Cornil I (2016)
Expanding the tools for identifying mononuclear phagocyte subsets in swine: Reagents to porcine CD11c and XCR1
Dev Comp Immunol, 65, 31-40
DOI 10.1016/j.dci.2016.06.015, PubMed 27345169

Guilliams M, Dutertre CA, Scott CL, McGovern N, Sichien D, Chakarov S, Van Gassen S, Chen J, Poidinger M, De Prijck S, Tavernier SJ, Low I, Irac SE, Mattar CN, Sumatoh HR, Low GHL, Chung TJK, Chan DKH, Tan KK, Hon TLK, Fossum E, Bogen B, Choolani M, Chan JKY, Larbi A et al. (2016)
Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species
Immunity, 45 (3), 669-684
DOI 10.1016/j.immuni.2016.08.015, PubMed 27637149

Zhou P, Chionh YT, Irac SE, Ahn M, Jia Ng JH, Fossum E, Bogen B, Ginhoux F, Irving AT, Dutertre CA, Wang LF (2016)
Unlocking bat immunology: establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages
Sci Rep, 6, 38597
DOI 10.1038/srep38597, PubMed 27934903

Publications 2015

Grødeland G, Fossum E, Bogen B (2015)
Polarizing T and B Cell Responses by APC-Targeted Subunit Vaccines
Front Immunol, 6, 367
DOI 10.3389/fimmu.2015.00367, PubMed 26257735

Nagy G, Huszthy PC, Fossum E, Konttinen Y, Nakken B, Szodoray P (2015)
Selected Aspects in the Pathogenesis of Autoimmune Diseases
Mediators Inflamm, 2015, 351732
DOI 10.1155/2015/351732, PubMed 26300591

Nakken B, Nagy G, Huszthy PC, Fossum E, Konttinen Y, Szodoray P (2015)
Inflammatory Mediators in Autoimmunity and Systemic Autoimmune Diseases
Mediators Inflamm, 2015, 878712
DOI 10.1155/2015/878712, PubMed 26346773

Terhorst D, Fossum E, Baranska A, Tamoutounour S, Malosse C, Garbani M, Braun R, Lechat E, Crameri R, Bogen B, Henri S, Malissen B (2015)
Laser-assisted intradermal delivery of adjuvant-free vaccines targeting XCR1+ dendritic cells induces potent antitumoral responses
J Immunol, 194 (12), 5895-902
DOI 10.4049/jimmunol.1500564, PubMed 25941327

Publications 2014

Balan S, Ollion V, Colletti N, Chelbi R, Montanana-Sanchis F, Liu H, Vu Manh TP, Sanchez C, Savoret J, Perrot I, Doffin AC, Fossum E, Bechlian D, Chabannon C, Bogen B, Asselin-Paturel C, Shaw M, Soos T, Caux C, Valladeau-Guilemond J, Dalod M (2014)
Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells
J Immunol, 193 (4), 1622-35
DOI 10.4049/jimmunol.1401243, PubMed 25009205

Dutertre CA, Jourdain JP, Rancez M, Amraoui S, Fossum E, Bogen B, Sanchez C, Couëdel-Courteille A, Richard Y, Dalod M, Feuillet V, Cheynier R, Hosmalin A (2014)
TLR3-responsive, XCR1+, CD141(BDCA-3)+/CD8α+-equivalent dendritic cells uncovered in healthy and simian immunodeficiency virus-infected rhesus macaques
J Immunol, 192 (10), 4697-708
DOI 10.4049/jimmunol.1302448, PubMed 24740505

Fossum E, Grødeland G, Terhorst D, Tveita AA, Vikse E, Mjaaland S, Henri S, Malissen B, Bogen B (2014)
Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8+ T-cell responses against influenza virus
Eur J Immunol, 45 (2), 624-35
DOI 10.1002/eji.201445080, PubMed 25410055

Publications 2013

Griffiths SJ, Koegl M, Boutell C, Zenner HL, Crump CM, Pica F, Gonzalez O, Friedel CC, Barry G, Martin K, Craigon MH, Chen R, Kaza LN, Fossum E, Fazakerley JK, Efstathiou S, Volpi A, Zimmer R, Ghazal P, Haas J (2013)
A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication
PLoS Pathog, 9 (8), e1003514
DOI 10.1371/journal.ppat.1003514, PubMed 23950709

Publications 2011

Bannoehr J, Ben Zakour NL, Reglinski M, Inglis NF, Prabhakaran S, Fossum E, Smith DG, Wilson GJ, Cartwright RA, Haas J, Hook M, van den Broek AH, Thoday KL, Fitzgerald JR (2011)
Genomic and surface proteomic analysis of the canine pathogen Staphylococcus pseudintermedius reveals proteins that mediate adherence to the extracellular matrix
Infect Immun, 79 (8), 3074-86
DOI 10.1128/IAI.00137-11, PubMed 21576333

Crozat K, Tamoutounour S, Vu Manh TP, Fossum E, Luche H, Ardouin L, Guilliams M, Azukizawa H, Bogen B, Malissen B, Henri S, Dalod M (2011)
Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α+ type
J Immunol, 187 (9), 4411-5
DOI 10.4049/jimmunol.1101717, PubMed 21948982

Publications 2010

Heinzelmann K, Scholz BA, Nowak A, Fossum E, Kremmer E, Haas J, Frank R, Kempkes B (2010)
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4/K10) is a novel interaction partner of CSL/CBF1, the major downstream effector of Notch signaling
J Virol, 84 (23), 12255-64
DOI 10.1128/JVI.01484-10, PubMed 20861242

Publications 2009

Fossum E, Friedel CC, Rajagopala SV, Titz B, Baiker A, Schmidt T, Kraus T, Stellberger T, Rutenberg C, Suthram S, Bandyopadhyay S, Rose D, von Brunn A, Uhlmann M, Zeretzke C, Dong YA, Boulet H, Koegl M, Bailer SM, Koszinowski U, Ideker T, Uetz P, Zimmer R, Haas J (2009)
Evolutionarily conserved herpesviral protein interaction networks
PLoS Pathog, 5 (9), e1000570
DOI 10.1371/journal.ppat.1000570, PubMed 19730696

Publications 2008

Wu L, Fossum E, Joo CH, Inn KS, Shin YC, Johannsen E, Hutt-Fletcher LM, Hass J, Jung JU (2008)
Epstein-Barr virus LF2: an antagonist to type I interferon
J Virol, 83 (2), 1140-6
DOI 10.1128/JVI.00602-08, PubMed 18987133

Publications 2005

Uetz P, Dong YA, Zeretzke C, Atzler C, Baiker A, Berger B, Rajagopala SV, Roupelieva M, Rose D, Fossum E, Haas J (2005)
Herpesviral protein networks and their interaction with the human proteome
Science, 311 (5758), 239-42
DOI 10.1126/science.1116804, PubMed 16339411

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