Publications by Nils Eiel Steen

137 publications found

Publications 2025

  1. Andreou D, Steen NE, Jørgensen KN, Nerland S, Ueland T, Wortinger LA, Drabløs I, Calkova T, Ormerod MBEG, Sæther LS, Andreassen OA, Yolken RH, Agartz I (2025)
    Toxoplasma gondii associated with psychotic symptom load and cortisol in severe mental illness
    Schizophrenia (Heidelb), 11 (1), 80
    DOI 10.1038/s41537-025-00630-0, PubMed 40419482
  2. Hoffart Lunding S, Kreis IV, Rødevand L, Aas M, Frogner Werner MC, Torp Johansen I, Elkjær Greenwood Ormerod MB, Reponen E, Hjell G, Ringen PA, Vik Lagerberg T, Melle I, Andreassen OA, Simonsen C, Ueland T, Steen NE (2025)
    Self-harming behavior linked to earlier onset of cardiovascular disease in severe mental disorders
    Eur Psychiatry, 68 (1), e143
    DOI 10.1192/j.eurpsy.2025.10106, PubMed 40947592
  3. Kim M, Sharma N, Leonardsen EH, Rutherford S, Selbæk G, Persson K, Steen NE, Smeland OB, Ueland T, Richard G, Manoli A, Valk SL, Alnæs D, Beckman CF, Marquand AF, Andreassen OA, Westlye LT, Wolfers T, Moberget T (2025)
    Predicting Mental and Neurological Illnesses Based on Cerebellar Normative Features
    Biol Psychiatry Glob Open Sci, 5 (5), 100541
    DOI 10.1016/j.bpsgos.2025.100541, PubMed 40678689
  4. Kreis I, Fjelnseth Wold K, Åsbø G, Bärthel Flaaten C, Engen MJ, Lyngstad SH, Hustad Widing L, Sheikh MA, Frogner Werner MC, Bakken E, Ueland T, Steen NE, Melle I (2025)
    Recent cannabis use affects the association between baseline immune markers and long-term outcomes in psychosis
    Transl Psychiatry, 15 (1), 282
    DOI 10.1038/s41398-025-03498-x, PubMed 40813774
  5. Ormerod MBEG, Sheikh MA, Ueland T, Hjell G, Rødevand L, Sæther LS, Lunding SH, Johansen IT, Andreou D, Ueland T, Lagerberg TV, Melle I, Djurovic S, Andreassen OA, Steen NE (2025)
    Minor immunomodulatory effects of psychotropics suggested in severe mental disorders: Associations of antipsychotics with beta defensin 2, antidepressants with C-reactive protein, and mood stabilizers with soluble interleukin 2 receptor
    Eur Psychiatry, 68 (1), e140
    DOI 10.1192/j.eurpsy.2025.10104, PubMed 40936381
  6. Ormerod MBEG, Ueland T, Aas M, Hjell G, Rødevand L, Sæther LS, Lunding SH, Johansen IT, Mlakar V, Andreou D, Ueland T, Lagerberg TV, Melle I, Djurovic S, Andreassen OA, Steen NE (2025)
    Limited evidence of association between dysregulated immune marker levels and telomere length in severe mental disorders
    Acta Neuropsychiatr, 37, e4
    DOI 10.1017/neu.2024.62, PubMed 39844366
  7. Pentz AB, Mäki-Marttunen V, van Jole O, Nerland S, Melle I, Steen NE, Agartz I, Westlye LT, Haukvik UK, Moberget T, Jönsson EG, Andreassen OA, Elvsåshagen T (2025)
    Auditory MMN is associated with the volume of thalamic higher order nuclei in individuals with psychotic disorders and healthy controls
    Schizophr Res, 276, 222-233
    DOI 10.1016/j.schres.2025.01.031, PubMed 39922063
  8. van der Meer D, Rahman Z, Ottas A, Parekh P, Kutrolli G, Stinson SE, Koromina M, Rokicki J, Sønderby IE, Parker N, Tesfaye M, Hindley G, Rødevand LN, Koch E, Estonian Biobank Research Team, Steen NE, Berg JP, O'Connell KS, Smeland OB, Frei O, Dale AM, Djurovic S, Lehto K, Alver M, Milani L et al. (2025)
    Pleiotropic and sex-specific genetic mechanisms of circulating metabolic markers
    Nat Commun, 16 (1), 4961
    DOI 10.1038/s41467-025-60058-z, PubMed 40436851

Publications 2024

  1. Andreou D, Steen NE, Jørgensen KN, Ueland T, Wortinger LA, Mørch-Johnsen L, Drabløs I, Calkova T, Yolken RH, Andreassen OA, Agartz I (2024)
    Increased Herpes simplex virus 1, Toxoplasma gondii and Cytomegalovirus antibody concentrations in severe mental illness
    Transl Psychiatry, 14 (1), 498
    DOI 10.1038/s41398-024-03198-y, PubMed 39695093
  2. Andreou D, Steen NE, Mørch-Johnsen L, Jørgensen KN, Wortinger LA, Barth C, Szabo A, O'Connell KS, Lekva T, Hjell G, Johansen IT, Ormerod MBEG, Haukvik UK, Aukrust P, Djurovic S, Yolken RH, Andreassen OA, Ueland T, Agartz I (2024)
    Toxoplasma gondii infection associated with inflammasome activation and neuronal injury
    Sci Rep, 14 (1), 5327
    DOI 10.1038/s41598-024-55887-9, PubMed 38438515
  3. Inova A, Birkenæs V, Quintana DS, Ormerod MBEG, Ueland T, Ueland T, Djurovic S, Andreassen O, Steen NE, Aas M (2024)
    Cortisol and C-reactive protein (CRP) regulation in severe mental disorders
    Psychoneuroendocrinology, 172, 107272
    DOI 10.1016/j.psyneuen.2024.107272, PubMed 39740359
  4. Johansen IT, Steen NE, Rødevand L, Lunding SH, Hjell G, Ormerod MBEG, Agartz I, Melle I, Lagerberg TV, Nerhus M, Andreassen OA (2024)
    Sex differences in autonomic adverse effects related to antipsychotic treatment and associated hormone profiles
    Schizophrenia (Heidelb), 10 (1), 6
    DOI 10.1038/s41537-023-00430-4, PubMed 38182592
  5. Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2024)
    Dissecting the Shared Genetic Architecture of Common Epilepsies With Cortical Brain Morphology
    Neurol Genet, 10 (3), e200143
    DOI 10.1212/NXG.0000000000200143, PubMed 38817246
  6. Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Ueland T, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2024)
    Unraveling the shared genetics of common epilepsies and general cognitive ability
    Seizure, 122, 105-112
    DOI 10.1016/j.seizure.2024.09.016, PubMed 39388989
  7. Koch E, Kämpe A, Alver M, Sigurðarson S, Einarsson G, Partanen J, Smith RL, Jaholkowski P, Taipale H, Lähteenvuo M, Steen NE, Smeland OB, Djurovic S, Molden E, FinnGen, Estonian Biobank Research Team, Sigurdsson E, Stefánsson H, Stefánsson K, Palotie A, Milani L, O'Connell KS, Andreassen OA (2024)
    Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study
    Neuropsychopharmacology, 49 (7), 1113-1119
    DOI 10.1038/s41386-023-01792-0, PubMed 38184734
  8. Mlakar V, Akkouh I, Halff EF, Srivastava DP, Birkenæs V, Ueland T, Quintana DS, Ormerod MBEG, Steen NE, Djurovic S, Andreassen OA, Aas M (2024)
    Telomere biology and its maintenance in schizophrenia spectrum disorders: Exploring links to cognition
    Schizophr Res, 272, 89-95
    DOI 10.1016/j.schres.2024.08.011, PubMed 39208769
  9. Pentz AB, O'Connel KS, van Jole O, Timpe CMF, Slapø NB, Melle I, Lagerberg TV, Steen NE, Westlye LT, Haukvik UK, Moberget T, Jönsson EG, Andreassen OA, Elvsåshagen T (2024)
    Mismatch negativity and polygenic risk scores for schizophrenia and bipolar disorder
    Schizophr Res, 264, 314-326
    DOI 10.1016/j.schres.2024.01.013, PubMed 38215567
  10. Sartorius AM, Rokicki J, Birkeland S, Bettella F, Barth C, de Lange AG, Haram M, Shadrin A, Winterton A, Steen NE, Schwarz E, Stein DJ, Andreassen OA, van der Meer D, Westlye LT, Theofanopoulou C, Quintana DS (2024)
    An evolutionary timeline of the oxytocin signaling pathway
    Commun Biol, 7 (1), 471
    DOI 10.1038/s42003-024-06094-9, PubMed 38632466
  11. Szabo A, O'Connell KS, Akkouh IA, Ueland T, Sønderby IE, Hope S, Røe AB, Dønnum MS, Sjaastad I, Steen NE, Ueland T, Sæther LS, Osete JR, Andreassen OA, Nærland T, Djurovic S (2024)
    Elevated levels of peripheral and central nervous system immune markers reflect innate immune dysregulation in autism spectrum disorder
    Psychiatry Res, 342, 116245
    DOI 10.1016/j.psychres.2024.116245, PubMed 39481220
  12. Sæther LS, Ueland T, Haatveit B, Vaskinn A, Bärthel Flaaten C, Mohn C, E G Ormerod MB, Aukrust P, Melle I, Steen NE, Andreassen OA, Ueland T (2024)
    Longitudinal course of inflammatory-cognitive subgroups across first treatment severe mental illness and healthy controls
    Psychol Med, 54 (12), 1-11 (in press)
    DOI 10.1017/S003329172400206X, PubMed 39354711
  13. van der Meer D, Cheng W, Rokicki J, Fernandez-Cabello S, Shadrin A, Smeland OB, Ehrhart F, Gülöksüz S, Pries LK, Lin B, Rutten BPF, van Os J, O'Donovan M, Richards AL, Steen NE, Djurovic S, Westlye LT, Andreassen OA, Kaufmann T, Genetic Risk and Outcome of Psychosis investigators (GROUP), European Network of National Schizophrenia Networks Studying Gene-Environment Interactions Work Package 6 (EU-GEI WP6) (2024)
    Clustering Schizophrenia Genes by Their Temporal Expression Patterns Aids Functional Interpretation
    Schizophr Bull, 50 (2), 327-338
    DOI 10.1093/schbul/sbad140, PubMed 37824720
  14. Varden Gjerde K, Bartz-Johannessen C, Steen VM, Andreassen OA, Steen NE, Ueland T, Lekva T, Rettenbacher M, Joa I, Reitan SK, Johnsen E, Kroken RA (2024)
    Cellular adhesion molecules in drug-naïve and previously medicated patients with schizophrenia-spectrum disorders
    Schizophr Res, 267, 223-229
    DOI 10.1016/j.schres.2024.03.029, PubMed 38574562

Publications 2023

  1. Cheng W, Parker N, Karadag N, Koch E, Hindley G, Icick R, Shadrin A, O'Connell KS, Bjella T, Bahrami S, Rahman Z, Tesfaye M, Jaholkowski P, Rødevand L, Holen B, Lagerberg TV, Steen NE, Djurovic S, Dale AM, Frei O, Smeland OB, Andreassen OA (2023)
    The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study
    Lancet Psychiatry, 10 (6), 441-451
    DOI 10.1016/S2215-0366(23)00143-8, PubMed 37208114
  2. Hiller JK, Jangmo A, Tesli MS, Jaholkowski PP, Hoseth EZ, Steen NE, Haram M (2023)
    Lipid Biomarker Research in Bipolar Disorder: A Scoping Review of Trends, Challenges, and Future Directions
    Biol Psychiatry Glob Open Sci, 3 (4), 594-604
    DOI 10.1016/j.bpsgos.2023.07.004, PubMed 37881590
  3. Hjell G, Rokicki J, Szabo A, Holst R, Tesli N, Bell C, Fischer-Vieler T, Werner MCF, Lunding SH, Ormerod MBEG, Johansen IT, Djurovic S, Ueland T, Andreassen OA, Melle I, Lagerberg TV, Mørch-Johnsen L, Steen NE, Haukvik UK (2023)
    Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy
    BMC Psychiatry, 23 (1), 659
    DOI 10.1186/s12888-023-05154-4, PubMed 37674162
  4. Karadag N, Shadrin AA, O'Connell KS, Hindley GFL, Rahman Z, Parker N, Bahrami S, Fominykh V, Cheng W, Holen B, Alvestad S, Taubøll E, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2023)
    Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders
    Brain, 146 (8), 3392-3403
    DOI 10.1093/brain/awad038, PubMed 36757824
  5. Lunding SH, Ueland T, Aas M, Høegh MC, Werner MCF, Rødevand L, Johansen IT, Hjell G, Ormerod MBEG, Ringen PA, Ottesen A, Lagerberg TV, Melle I, Andreassen OA, Simonsen C, Steen NE (2023)
    Tobacco smoking related to childhood trauma mediated by cognitive control and impulsiveness in severe mental disorders
    Schizophr Res, 261, 236-244
    DOI 10.1016/j.schres.2023.09.041, PubMed 37806047
  6. Mlakar V, Birkenæs V, Elvsaashagen T, Ormerod MBEG, Quintana DS, Ueland T, Melle I, Lagerberg TV, Djurovic S, Martin-Ruiz C, Steen NE, Andreassen OA, Aas M (2023)
    Telomere length and verbal learning in bipolar disorders
    J Affect Disord, 339, 555-560
    DOI 10.1016/j.jad.2023.07.087, PubMed 37459977
  7. O'Connell KS, Koch E, Lenk HÇ, Akkouh IA, Hindley G, Jaholkowski P, Smith RL, Holen B, Shadrin AA, Frei O, Smeland OB, Steen NE, Dale AM, Molden E, Djurovic S, Andreassen OA (2023)
    Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia
    Psychiatry Res, 325, 115217
    DOI 10.1016/j.psychres.2023.115217, PubMed 37146461
  8. Parker N, Cheng W, Hindley GFL, O'Connell KS, Karthikeyan S, Holen B, Shadrin AA, Rahman Z, Karadag N, Bahrami S, Lin A, Steen NE, Ueland T, Aukrust P, Djurovic S, Dale AM, Smeland OB, Frei O, Andreassen OA (2023)
    Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts
    Biol Psychiatry, 95 (1), 62-71
    DOI 10.1016/j.biopsych.2023.06.008, PubMed 37348803
  9. Pentz AB, Timpe CMF, Normann EM, Slapø NB, Melle I, Lagerberg TV, Steen NE, Westlye LT, Jönsson EG, Haukvik UK, Moberget T, Andreassen OA, Elvsåshagen T (2023)
    Mismatch negativity in schizophrenia spectrum and bipolar disorders: Group and sex differences and associations with symptom severity
    Schizophr Res, 261, 80-93
    DOI 10.1016/j.schres.2023.09.012, PubMed 37716205
  10. Reponen EJ, Ueland T, Rokicki J, Bettella F, Aas M, Werner MCF, Dieset I, Steen NE, Andreassen OA, Tesli M (2023)
    Polygenic risk for schizophrenia and bipolar disorder in relation to cardiovascular biomarkers
    Eur Arch Psychiatry Clin Neurosci, 274 (5), 1223-1230
    DOI 10.1007/s00406-023-01591-0, PubMed 37145175
  11. Rødevand L, Rahman Z, Hindley GFL, Smeland OB, Frei O, Tekin TF, Kutrolli G, Bahrami S, Hoseth EZ, Shadrin A, Lin A, Djurovic S, Dale AM, Steen NE, Andreassen OA (2023)
    Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors
    Am J Psychiatry, 180 (11), 815-826
    DOI 10.1176/appi.ajp.20220660, PubMed 37752828
  12. Slapø NB, Nerland S, Nordbø Jørgensen K, Mørch-Johnsen L, Pettersen JH, Roelfs D, Parker N, Valstad M, Pentz A, Timpe CMF, Richard G, Beck D, Werner MCF, Lagerberg TV, Melle I, Agartz I, Westlye LT, Steen NE, Andreassen OA, Moberget T, Elvsåshagen T, Jönsson EG (2023)
    Auditory Cortex Thickness Is Associated With N100 Amplitude in Schizophrenia Spectrum Disorders
    Schizophr Bull Open, 4 (1), sgad015
    DOI 10.1093/schizbullopen/sgad015, PubMed 38812720
  13. Steen NE, Rahman Z, Szabo A, Hindley GFL, Parker N, Cheng W, Lin A, O'Connell KS, Sheikh MA, Shadrin A, Bahrami S, Karthikeyan S, Hoseth EZ, Dale AM, Aukrust P, Smeland OB, Ueland T, Frei O, Djurovic S, Andreassen OA (2023)
    Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities
    Schizophr Bull, 49 (5), 1345-1354
    DOI 10.1093/schbul/sbad082, PubMed 37319439
  14. Torsvik A, Brattbakk HR, Trentani A, Holdhus R, Stansberg C, Bartz-Johannessen CA, Hughes T, Steen NE, Melle I, Djurovic S, Andreassen OA, Steen VM (2023)
    Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes
    Transl Psychiatry, 13 (1), 147
    DOI 10.1038/s41398-023-02442-1, PubMed 37147304
  15. Aas M, Andreassen OA, Gjerstad J, Rødevand L, Hjell G, Johansen IT, Lunding SH, Ormerod MBEG, Lagerverg TV, Steen NE, Djurovic S, Akkouh I (2023)
    Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders
    Sci Rep, 13 (1), 13845
    DOI 10.1038/s41598-023-40310-6, PubMed 37620394

Publications 2022

  1. Beck D, de Lange AG, Alnæs D, Maximov II, Pedersen ML, Leinhard OD, Linge J, Simon R, Richard G, Ulrichsen KM, Dørum ES, Kolskår KK, Sanders AM, Winterton A, Gurholt TP, Kaufmann T, Steen NE, Nordvik JE, Andreassen OA, Westlye LT (2022)
    Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults
    Neuroimage Clin, 33, 102949
    DOI 10.1016/j.nicl.2022.102949, PubMed 35114636
  2. Birkenes V, Elvsahagen T, Westlye LT, Hoegh MC, Haram M, Werner MCF, Quintana DS, Lunding SH, Martin-Ruiz C, Agartz I, Djurovic S, Steen NE, Andreassen OA, Aas M (2022)
    Telomeres are shorter and associated with number of suicide attempts in affective disorders
    J. Affect. Disord., 297, 1032-1039
    DOI 10.1016/j.jad.2021.08.135
  3. Elkjaer Greenwood Ormerod MB, Ueland T, Frogner Werner MC, Hjell G, Rødevand L, Sæther LS, Lunding SH, Johansen IT, Ueland T, Lagerberg TV, Melle I, Djurovic S, Andreassen OA, Steen NE (2022)
    Composite immune marker scores associated with severe mental disorders and illness course
    Brain Behav Immun Health, 24, 100483
    DOI 10.1016/j.bbih.2022.100483, PubMed 35856063
  4. Engh JA, Ueland T, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Hope S, Høegh MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Wedervang-Resell K, Weibell MA, Westlye LT, Djurovic S et al. (2022)
    Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
    Schizophr Bull, 48 (1), 37-46
    DOI 10.1093/schbul/sbab106, PubMed 34499169
  5. Gjerde PB, Steen SW, Vedal TSJ, Steen NE, Reponen EJ, Andreassen OA, Steen VM, Melle I (2022)
    Lifetime Cannabis Use Is Not Associated With Negative Beliefs About Medication in Patients With First Treatment Psychosis
    Front Psychiatry, 13, 824051
    DOI 10.3389/fpsyt.2022.824051, PubMed 35422717
  6. Hjell G, Szabo A, Mørch-Johnsen L, Holst R, Tesli N, Bell C, Fischer-Vieler T, Werner MCF, Lunding SH, Ormerod MBEG, Johansen IT, Dieset I, Djurovic S, Melle I, Ueland T, Andreassen OA, Steen NE, Haukvik UK (2022)
    Interleukin-18 signaling system links to agitation in severe mental disorders
    Psychoneuroendocrinology, 140, 105721
    DOI 10.1016/j.psyneuen.2022.105721, PubMed 35301151
  7. Icick R, Melle I, Etain B, Høegh MC, Gard S, Aminoff SR, Leboyer M, Andreassen OA, Belzeaux R, Henry C, Bjella TD, Kahn JP, Steen NE, Bellivier F, Lagerberg TV (2022)
    Preventive Medication Patterns in Bipolar Disorder and Their Relationship With Comorbid Substance Use Disorders in a Cross-National Observational Study
    Front Psychiatry, 13, 813256
    DOI 10.3389/fpsyt.2022.813256, PubMed 35592382
  8. Johansen IT, Steen NE, Haram M, Rødevand L, Werner MCF, Lunding SH, Hjell G, Agartz I, Melle I, Lagerberg TV, Nerhus M, Andreassen OA (2022)
    Sex differences in antipsychotic-related triglyceride levels are associated with metabolic hormone differences in patients with severe mental disorders
    Schizophr Res, 243, 55-63
    DOI 10.1016/j.schres.2022.02.015, PubMed 35240428
  9. Johansen IT, Steen NE, Rødevand L, Werner MCF, Lunding SH, Hjell G, Ormerod MBEG, Agartz I, Melle I, Lagerberg TV, Nerhus M, Andreassen OA (2022)
    Sex-specific associations between metabolic hormones, severe mental disorders and antipsychotic treatment
    Psychoneuroendocrinology, 146, 105927
    DOI 10.1016/j.psyneuen.2022.105927, PubMed 36152455
  10. Rokicki J, Kaufmann T, de Lange AG, van der Meer D, Bahrami S, Sartorius AM, Haukvik UK, Steen NE, Schwarz E, Stein DJ, Nærland T, Andreassen OA, Westlye LT, Quintana DS (2022)
    Oxytocin receptor expression patterns in the human brain across development
    Neuropsychopharmacology, 47 (8), 1550-1560
    DOI 10.1038/s41386-022-01305-5, PubMed 35347267
  11. Sheikh MA, O'Connell KS, Lekva T, Szabo A, Akkouh IA, Osete JR, Agartz I, Engh JA, Andreou D, Boye B, Bøen E, Elvsåshagen T, Hope S, Frogner Werner MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Melle I, Drange OK, Morken G, Nærland T, Sørensen K, Vaaler AE, Weibell MA et al. (2022)
    Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
    Biol Psychiatry, 93 (2), 187-196
    DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530
  12. Sæther LS, Ueland T, Haatveit B, Maglanoc LA, Szabo A, Djurovic S, Aukrust P, Roelfs D, Mohn C, Ormerod MBEG, Lagerberg TV, Steen NE, Melle I, Andreassen OA, Ueland T (2022)
    Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
    Mol Psychiatry, 28 (3), 1284-1292
    DOI 10.1038/s41380-022-01924-w, PubMed 36577840
  13. Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G et al. (2022)
    Mapping genomic loci implicates genes and synaptic biology in schizophrenia
    Nature, 604 (7906), 502-508
    DOI 10.1038/s41586-022-04434-5, PubMed 35396580
  14. Werner MCF, Wirgenes KV, Shadrin A, Lunding SH, Rødevand L, Hjell G, Ormerod MBEG, Haram M, Agartz I, Djurovic S, Melle I, Aukrust P, Ueland T, Andreassen OA, Steen NE (2022)
    Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis
    Transl Psychiatry, 12 (1), 38
    DOI 10.1038/s41398-022-01811-6, PubMed 35082268
  15. Werner MCF, Wirgenes KV, Shadrin AA, Lunding SH, Rødevand L, Hjell G, Ormerod MBEG, Haram M, Agartz I, Djurovic S, Melle I, Aukrust P, Ueland T, Andreassen OA, Steen NE (2022)
    Limited association between infections, autoimmune disease and genetic risk and immune activation in severe mental disorders
    Prog Neuropsychopharmacol Biol Psychiatry, 116, 110511
    DOI 10.1016/j.pnpbp.2022.110511, PubMed 35063598
  16. Winterton A, Bettella F, Beck D, Gurholt TP, Steen NE, Rødevand L, Westlye LT, Andreassen OA, Quintana DS (2022)
    The oxytocin signalling gene pathway contributes to the association between loneliness and cardiometabolic health
    Psychoneuroendocrinology, 144, 105875
    DOI 10.1016/j.psyneuen.2022.105875, PubMed 35939863
  17. Aas M, Ueland T, Lagerberg TV, Melle I, Aminoff SR, Hoegh MC, Lunding SH, Laskemoen JF, Steen NE, Andreassen OA (2022)
    Retrospectively assessed childhood trauma experiences are associated with illness severity in mental disorders adjusted for symptom state
    Psychiatry Res, 320, 115045
    DOI 10.1016/j.psychres.2022.115045, PubMed 36621206

Publications 2021

  1. Andreou D, Steen NE, Jørgensen KN, Smelror RE, Wedervang-Resell K, Nerland S, Westlye LT, Nærland T, Myhre AM, Joa I, Reitan SMK, Vaaler A, Morken G, Bøen E, Elvsåshagen T, Boye B, Malt UF, Aukrust P, Skrede S, Kroken RA, Johnsen E, Djurovic S, Andreassen OA, Ueland T, Agartz I (2021)
    Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
    Psychol Med, 53 (4), 1479-1488
    DOI 10.1017/S0033291721003056, PubMed 35387700
  2. Bahrami S, Shadrin A, Frei O, O'Connell KS, Bettella F, Krull F, Fan CC, Røssberg JI, Hindley G, Ueland T, Dale AM, Djurovic S, Steen NE, Smeland OB, Andreassen OA (2021)
    Genetic loci shared between major depression and intelligence with mixed directions of effect
    Nat Hum Behav, 5 (6), 795-801
    DOI 10.1038/s41562-020-01031-2, PubMed 33462475
  3. Beck D, de Lange AG, Pedersen ML, Alnaes D, Maximov II, Voldsbekk I, Richard G, Sanders AM, Ulrichsen KM, Dørum ES, Kolskår KK, Høgestøl EA, Steen NE, Djurovic S, Andreassen OA, Nordvik JE, Kaufmann T, Westlye LT (2021)
    Cardiometabolic risk factors associated with brain age and accelerate brain ageing
    Hum Brain Mapp, 43 (2), 700-720
    DOI 10.1002/hbm.25680, PubMed 34626047
  4. Bigseth TT, Engh JA, Egeland J, Andersen E, Andreassen OA, Bang-Kittilsen G, Falk RS, Holmen TL, Lindberg M, Mordal J, Nielsen J, Steen NE, Ueland T, Vang T, Fredriksen M (2021)
    Exploring low grade inflammation by soluble urokinase plasminogen activator receptor levels in schizophrenia: a sex-dependent association with depressive symptoms
    BMC Psychiatry, 21 (1), 527
    DOI 10.1186/s12888-021-03522-6, PubMed 34702245
  5. Bigseth TT, Fredriksen M, Egeland J, Andersen E, Andreassen OA, Bang-Kittilsen G, Falk RS, Holmen TL, Martinsen EW, Mordal J, Nielsen J, Steen NE, Ueland T, Vang T, Engh JA (2021)
    Elevated levels of soluble urokinase plasminogen activator receptor as a low-grade inflammation marker in schizophrenia: A case-control study
    Schizophr Res, 228, 190-192
    DOI 10.1016/j.schres.2020.11.051, PubMed 33450603
  6. Birkenæs V, Elvsåshagen T, Westlye LT, Høegh MC, Haram M, Werner MCF, Quintana DS, Lunding SH, Martin-Ruiz C, Agartz I, Djurovic S, Steen NE, Andreassen OA, Aas M (2021)
    Telomeres are shorter and associated with number of suicide attempts in affective disorders
    J Affect Disord, 295, 1032-1039
    DOI 10.1016/j.jad.2021.08.135, PubMed 34706411
  7. Fjukstad KK, Athanasiu L, Bahrami S, O'Connell KS, van der Meer D, Bettella F, Dieset I, Steen NE, Djurovic S, Spigset O, Andreassen OA (2021)
    Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study
    Pharmacogenomics J, 21 (5), 574-585
    DOI 10.1038/s41397-021-00234-8, PubMed 33824429
  8. Gjerde PB, Simonsen CE, Lagerberg TV, Steen NE, Andreassen OA, Steen VM, Melle I (2021)
    Sex-Specific Effect of Serum Lipids and Body Mass Index on Psychotic Symptoms, a Cross-Sectional Study of First-Episode Psychosis Patients
    Front Psychiatry, 12, 723158
    DOI 10.3389/fpsyt.2021.723158, PubMed 34744818
  9. Gurholt TP, Kaufmann T, Frei O, Alnæs D, Haukvik UK, van der Meer D, Moberget T, O'Connell KS, Leinhard OD, Linge J, Simon R, Smeland OB, Sønderby IE, Winterton A, Steen NE, Westlye LT, Andreassen OA (2021)
    Population-based body-brain mapping links brain morphology with anthropometrics and body composition
    Transl Psychiatry, 11 (1), 295
    DOI 10.1038/s41398-021-01414-7, PubMed 34006848
  10. Hindley G, Bahrami S, Steen NE, O'Connell KS, Frei O, Shadrin A, Bettella F, Rødevand L, Fan CC, Dale AM, Djurovic S, Smeland OB, Andreassen OA (2021)
    Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking
    Transl Psychiatry, 11 (1), 466
    DOI 10.1038/s41398-021-01576-4, PubMed 34497263
  11. Krull F, Akkouh I, Hughes T, Bettella F, Athanasiu L, Smeland OB, O'Connell KS, Brattbakk HR, Steen VM, Steen NE, Djurovic S, Andreassen OA (2021)
    Dose-dependent transcriptional effects of lithium and adverse effect burden in a psychiatric cohort
    Prog Neuropsychopharmacol Biol Psychiatry, 112, 110408
    DOI 10.1016/j.pnpbp.2021.110408, PubMed 34320404
  12. Lunding SH, Simonsen C, Aas M, Rødevand L, Werner MCF, Laskemoen JF, Hjell G, Ringen PA, Lagerberg TV, Melle I, Andreassen OA, Ueland T, Steen NE (2021)
    Childhood trauma and cardiometabolic risk in severe mental disorders: The mediating role of cognitive control
    Eur Psychiatry, 64 (1), e24
    DOI 10.1192/j.eurpsy.2021.14, PubMed 33775258
  13. O'Connell KS, Frei O, Bahrami S, Smeland OB, Bettella F, Cheng W, Chu Y, Hindley G, Lin A, Shadrin A, Barrett EA, Lagerberg TV, Steen NE, Dale AM, Djurovic S, Andreassen OA (2021)
    Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes
    Biol Psychiatry, 90 (9), 621-631
    DOI 10.1016/j.biopsych.2021.07.007, PubMed 34482950
  14. Osete JR, Akkouh IA, de Assis DR, Szabo A, Frei E, Hughes T, Smeland OB, Steen NE, Andreassen OA, Djurovic S (2021)
    Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders
    Mol Psychiatry, 26 (11), 6789-6805
    DOI 10.1038/s41380-021-01164-4, PubMed 34075196
  15. Reponen EJ, Tesli M, Dieset I, Steen NE, Vedal TSJ, Szabo A, Werner MCF, Lunding SH, Johansen IT, Rødevand LN, Andreassen OA, Ueland T (2021)
    Adiponectin Is Related to Cardiovascular Risk in Severe Mental Illness Independent of Antipsychotic Treatment
    Front Psychiatry, 12, 623192
    DOI 10.3389/fpsyt.2021.623192, PubMed 34122163
  16. Rødevand L, Bahrami S, Frei O, Chu Y, Shadrin A, O'Connell KS, Smeland OB, Elvsåshagen T, Hindley GFL, Djurovic S, Dale AM, Lagerberg TV, Steen NE, Andreassen OA (2021)
    Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
    Transl Psychiatry, 11 (1), 407
    DOI 10.1038/s41398-021-01527-z, PubMed 34301917
  17. Rødevand L, Bahrami S, Frei O, Lin A, Gani O, Shadrin A, Smeland OB, Connell KSO, Elvsåshagen T, Winterton A, Quintana DS, Hindley GFL, Werner MCF, Djurovic S, Dale AM, Lagerberg TV, Steen NE, Andreassen OA (2021)
    Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
    Transl Psychiatry, 11 (1), 3
    DOI 10.1038/s41398-020-01142-4, PubMed 33414458
  18. Szabo A, O'Connell KS, Ueland T, Sheikh MA, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Engh JA, Hope S, Collier Høegh M, Joa I, Johnsen E, Kroken RA, Vik Lagerberg T, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Sørensen K et al. (2021)
    Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
    Brain Behav Immun, 99, 299-306
    DOI 10.1016/j.bbi.2021.10.017, PubMed 34758379
  19. Valstad M, Roelfs D, Slapø NB, Timpe CMF, Rai A, Matziorinis AM, Beck D, Richard G, Sæther LS, Haatveit B, Nordvik JE, Hatlestad-Hall C, Einevoll GT, Mäki-Marttunen T, Haram M, Ueland T, Lagerberg TV, Steen NE, Melle I, Westlye LT, Jönsson EG, Andreassen OA, Moberget T, Elvsåshagen T (2021)
    Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder
    Schizophr Bull, 47 (6), 1751-1760
    DOI 10.1093/schbul/sbab049, PubMed 33963856
  20. Winterton A, Bettella F, de Lange AG, Haram M, Steen NE, Westlye LT, Andreassen OA, Quintana DS (2021)
    Oxytocin-pathway polygenic scores for severe mental disorders and metabolic phenotypes in the UK Biobank
    Transl Psychiatry, 11 (1), 599
    DOI 10.1038/s41398-021-01725-9, PubMed 34824196
  21. Wiström ED, O'Connell KS, Karadag N, Bahrami S, Hindley GFL, Lin A, Cheng W, Steen NE, Shadrin A, Frei O, Djurovic S, Dale AM, Andreassen OA, Smeland OB (2021)
    Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci
    Addiction, 117 (3), 600-610
    DOI 10.1111/add.15680, PubMed 34472679
  22. Aas M, Ueland T, Mørch RH, Laskemoen JF, Lunding SH, Reponen EJ, Cattaneo A, Agartz I, Melle I, Steen NE, Andreassen OA (2021)
    Physical activity and childhood trauma experiences in patients with schizophrenia or bipolar disorders
    World J Biol Psychiatry, 22 (8), 637-645
    DOI 10.1080/15622975.2021.1907707, PubMed 33779484

Publications 2020

  1. Akkouh IA, Ueland T, Hansson L, Inderhaug E, Hughes T, Steen NE, Aukrust P, Andreassen OA, Szabo A, Djurovic S (2020)
    Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
    Brain Behav Immun, 87, 634-644
    DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548
  2. Bahrami S, Steen NE, Shadrin A, O'Connell K, Frei O, Bettella F, Wirgenes KV, Krull F, Fan CC, Dale AM, Smeland OB, Djurovic S, Andreassen OA (2020)
    Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study
    JAMA Psychiatry, 77 (5), 503-512
    DOI 10.1001/jamapsychiatry.2019.4188, PubMed 31913414
  3. Benjamin BR, Valstad M, Elvsåshagen T, Jönsson EG, Moberget T, Winterton A, Haram M, Høegh MC, Lagerberg TV, Steen NE, Larsen L, Andreassen OA, Westlye LT, Quintana DS (2020)
    Heart rate variability is associated with disease severity in psychosis spectrum disorders
    Prog Neuropsychopharmacol Biol Psychiatry, 111, 110108
    DOI 10.1016/j.pnpbp.2020.110108, PubMed 32946948
  4. Hjell G, Mørch-Johnsen L, Holst R, Tesli N, Bell C, Lunding SH, Rødevand L, Werner MCF, Melle I, Andreassen OA, Lagerberg TV, Steen NE, Haukvik UK (2020)
    Disentangling the relationship between cholesterol, aggression, and impulsivity in severe mental disorders
    Brain Behav, 10 (9), e01751
    DOI 10.1002/brb3.1751, PubMed 32681586
  5. Hjelseng IV, Vaskinn A, Ueland T, Lunding SH, Reponen EJ, Steen NE, Andreassen OA, Aas M (2020)
    Childhood trauma is associated with poorer social functioning in severe mental disorders both during an active illness phase and in remission
    Schizophr Res, 243, 241-246
    DOI 10.1016/j.schres.2020.03.015, PubMed 32222348
  6. Hope S, Naerland T, Høiland AL, Torske T, Malt E, Abrahamsen T, Nerhus M, Wedervang-Resell K, Lonning V, Johannessen J, Steen NE, Agartz I, Stenberg N, Hundhausen T, Mørkrid L, Andreassen OA (2020)
    Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia: A comparison among participants between 2 and 53 years
    FASEB J, 34 (6), 8114-8124
    DOI 10.1096/fj.201900855RRR, PubMed 32323402
  7. Reponen EJ, Dieset I, Tesli M, Mørch RH, Aas M, Vedal TSJ, Haug E, Drange OK, Steen NE, Hope S, Szabo A, Gohar SM, Wedervang-Resell K, Djurovic S, Melle I, Aukrust P, Andreassen OA, Ueland T (2020)
    Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
    Front Psychiatry, 11, 672
    DOI 10.3389/fpsyt.2020.00672, PubMed 32754070
  8. Smeland OB, Bahrami S, Frei O, Shadrin A, O'Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA (2020)
    Correction: Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
    Mol Psychiatry, 25 (4), 914
    DOI 10.1038/s41380-019-0456-7, PubMed 31308466
  9. Smeland OB, Shadrin A, Bahrami S, Broce I, Tesli M, Frei O, Wirgenes KV, O'Connell KS, Krull F, Bettella F, Steen NE, Sugrue L, Wang Y, Svenningsson P, Sharma M, Pihlstrøm L, Toft M, O'Donovan M, Djurovic S, Desikan R, Dale AM, Andreassen OA (2020)
    Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci
    Biol Psychiatry, 89 (3), 227-235
    DOI 10.1016/j.biopsych.2020.01.026, PubMed 32201043
  10. Werner MCF, Wirgenes KV, Haram M, Bettella F, Lunding SH, Rødevand L, Hjell G, Agartz I, Djurovic S, Melle I, Andreassen OA, Steen NE (2020)
    Indicated association between polygenic risk score and treatment-resistance in a naturalistic sample of patients with schizophrenia spectrum disorders
    Schizophr Res, 218, 55-62
    DOI 10.1016/j.schres.2020.03.006, PubMed 32171635
  11. Winterton A, Rødevand L, Westlye LT, Steen NE, Andreassen OA, Quintana DS (2020)
    Associations of loneliness and social isolation with cardiovascular and metabolic health: a systematic review and meta-analysis protocol
    Syst Rev, 9 (1), 102
    DOI 10.1186/s13643-020-01369-8, PubMed 32366295
  12. Winterton A, Westlye LT, Steen NE, Andreassen OA, Quintana DS (2020)
    Improving the precision of intranasal oxytocin research
    Nat Hum Behav, 5 (1), 9-18
    DOI 10.1038/s41562-020-00996-4, PubMed 33257880
  13. Aas M, Ueland T, Inova A, Melle I, Andreassen OA, Steen NE (2020)
    Childhood Trauma Is Nominally Associated With Elevated Cortisol Metabolism in Severe Mental Disorder
    Front Psychiatry, 11, 391
    DOI 10.3389/fpsyt.2020.00391, PubMed 32528319

Publications 2019

  1. Gjerde PB, Simonsen CE, Lagerberg TV, Steen NE, Ueland T, Andreassen OA, Steen VM, Melle I (2019)
    Improvement in verbal learning over the first year of antipsychotic treatment is associated with serum HDL levels in a cohort of first episode psychosis patients
    Eur Arch Psychiatry Clin Neurosci, 270 (1), 49-58
    DOI 10.1007/s00406-019-01017-w, PubMed 31028479
  2. Gohar SM, Dieset I, Steen NE, Mørch RH, Vedal TSJ, Reponen EJ, Steen VM, Andreassen OA, Melle I (2019)
    Association between leptin levels and severity of suicidal behaviour in schizophrenia spectrum disorders
    Acta Psychiatr Scand, 139 (5), 464-471
    DOI 10.1111/acps.13019, PubMed 30848483
  3. O'Connell KS, Shadrin A, Bahrami S, Smeland OB, Bettella F, Frei O, Krull F, Askeland RB, Walters GB, Davíðsdóttir K, Haraldsdóttir GS, Guðmundsson ÓÓ, Stefánsson H, Fan CC, Steen NE, Reichborn-Kjennerud T, Dale AM, Stefánsson K, Djurovic S, Andreassen OA (2019)
    Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder
    Mol Psychiatry, 26 (8), 4055-4065
    DOI 10.1038/s41380-019-0613-z, PubMed 31792363
  4. O'Connell KS, Shadrin A, Smeland OB, Bahrami S, Frei O, Bettella F, Krull F, Fan CC, Askeland RB, Knudsen GPS, Halmøy A, Steen NE, Ueland T, Walters GB, Davíðsdóttir K, Haraldsdóttir GS, Guðmundsson ÓÓ, Stefánsson H, Reichborn-Kjennerud T, Haavik J, Dale AM, Stefánsson K, Djurovic S, Andreassen OA (2019)
    Identification of Genetic Loci Shared Between Attention-Deficit/Hyperactivity Disorder, Intelligence, and Educational Attainment
    Biol Psychiatry, 87 (12), 1052-1062
    DOI 10.1016/j.biopsych.2019.11.015, PubMed 32061372
  5. Ringen PA, Reponen EJ, Vedal TSJ, Andreassen OA, Steen NE, Melle I (2019)
    Predictors for Antipsychotic Dosage Change in the First Year of Treatment in Schizophrenia Spectrum and Bipolar Disorders
    Front Psychiatry, 10, 649
    DOI 10.3389/fpsyt.2019.00649, PubMed 31551838
  6. Rødevand L, Steen NE, Elvsåshagen T, Quintana DS, Reponen EJ, Mørch RH, Lunding SH, Vedal TSJ, Dieset I, Melle I, Lagerberg TV, Andreassen OA (2019)
    Cardiovascular risk remains high in schizophrenia with modest improvements in bipolar disorder during past decade
    Acta Psychiatr Scand, 139 (4), 348-360
    DOI 10.1111/acps.13008, PubMed 30697685
  7. Scott J, Hidalgo-Mazzei D, Strawbridge R, Young A, Resche-Rigon M, Etain B, Andreassen OA, Bauer M, Bennabi D, Blamire AM, Boumezbeur F, Brambilla P, Cattane N, Cattaneo A, Chupin M, Coello K, Cointepas Y, Colom F, Cousins DA, Dubertret C, Duchesnay E, Ferro A, Garcia-Estela A, Goikolea J, Grigis A et al. (2019)
    Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative
    Int J Bipolar Disord, 7 (1), 20
    DOI 10.1186/s40345-019-0156-x, PubMed 31552554
  8. Smeland OB, Bahrami S, Frei O, Shadrin A, O'Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA (2019)
    Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
    Mol Psychiatry, 25 (4), 844-853
    DOI 10.1038/s41380-018-0332-x, PubMed 30610197
  9. Steen NE, Dieset I, Hope S, Vedal TSJ, Smeland OB, Matson W, Kaddurah-Daouk R, Agartz I, Melle I, Djurovic S, Jönsson EG, Bogdanov M, Andreassen OA (2019)
    Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders
    Psychol Med, 50 (4), 595-606
    DOI 10.1017/S0033291719000400, PubMed 30867076
  10. Vedal TSJ, Steen NE, Birkeland KI, Dieset I, Reponen EJ, Laskemoen JF, Rødevand L, Melle I, Andreassen OA, Molden E, Jönsson EG (2019)
    Adipokine levels are associated with insulin resistance in antipsychotics users independently of BMI
    Psychoneuroendocrinology, 103, 87-95
    DOI 10.1016/j.psyneuen.2019.01.001, PubMed 30659986
  11. Aas M, Elvsåshagen T, Westlye LT, Kaufmann T, Athanasiu L, Djurovic S, Melle I, van der Meer D, Martin-Ruiz C, Steen NE, Agartz I, Andreassen OA (2019)
    Telomere length is associated with childhood trauma in patients with severe mental disorders
    Transl Psychiatry, 9 (1), 97
    DOI 10.1038/s41398-019-0432-7, PubMed 30898995
  12. Aas M, Pizzagalli DA, Laskemoen JF, Reponen EJ, Ueland T, Melle I, Agartz I, Steen NE, Andreassen OA (2019)
    Elevated hair cortisol is associated with childhood maltreatment and cognitive impairment in schizophrenia and in bipolar disorders
    Schizophr Res, 213, 65-71
    DOI 10.1016/j.schres.2019.01.011, PubMed 30660575

Publications 2018

  1. Gjerde PB, Jørgensen KN, Steen NE, Melle I, Andreassen OA, Steen VM, Agartz I (2018)
    Association between olanzapine treatment and brain cortical thickness and gray/white matter contrast is moderated by cholesterol in psychotic disorders
    Psychiatry Res Neuroimaging, 282, 55-63
    DOI 10.1016/j.pscychresns.2018.10.001, PubMed 30415175
  2. Gohar SM, Dieset I, Steen NE, Mørch RH, Iversen TS, Steen VM, Andreassen OA, Melle I (2018)
    Association between serum lipid levels, osteoprotegerin and depressive symptomatology in psychotic disorders
    Eur Arch Psychiatry Clin Neurosci, 269 (7), 795-802
    DOI 10.1007/s00406-018-0897-z, PubMed 29721726
  3. Hoseth EZ, Krull F, Dieset I, Mørch RH, Hope S, Gardsjord ES, Steen NE, Melle I, Brattbakk HR, Steen VM, Aukrust P, Djurovic S, Andreassen OA, Ueland T (2018)
    Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder
    Transl Psychiatry, 8 (1), 55
    DOI 10.1038/s41398-018-0102-1, PubMed 29507296
  4. Hoseth EZ, Krull F, Dieset I, Mørch RH, Hope S, Gardsjord ES, Steen NE, Melle I, Brattbakk HR, Steen VM, Aukrust P, Djurovic S, Andreassen OA, Ueland T (2018)
    Attenuated Notch signaling in schizophrenia and bipolar disorder
    Sci Rep, 8 (1), 5349
    DOI 10.1038/s41598-018-23703-w, PubMed 29593239
  5. Quintana DS, Steen NE, Andreassen OA (2018)
    The Promise of Intranasal Esketamine as a Novel and Effective Antidepressant
    JAMA Psychiatry, 75 (2), 123-124
    DOI 10.1001/jamapsychiatry.2017.3738, PubMed 29282452
  6. Vedal TSJ, Steen NE, Birkeland KI, Dieset I, Reponen EJ, Laskemoen JF, Rødevand L, Melle I, Andreassen OA, Molden E, Jönsson EG (2018)
    Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication
    J Psychiatr Res, 106, 74-81
    DOI 10.1016/j.jpsychires.2018.09.014, PubMed 30292780
  7. Vedal TSJ, Steen NE, Birkeland KI, Dieset I, Reponen EJ, Laskemoen JF, Rødevand L, Melle I, Andreassen OA, Molden E, Jönsson EG (2018)
    Response: Are thyroid abnormalities only related to antipsychotic treatment in patients with severe mental disorders?
    J Psychiatr Res, 117, 150
    DOI 10.1016/j.jpsychires.2018.11.012, PubMed 30454945
  8. Aas M, Dieset I, Mørch R, Steen NE, Hope S, Reponen EJ, Laskemoen JF, Ueland T, Aukrust P, Melle I, Agartz I, Andreassen OA (2018)
    Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders
    Schizophr Res, 205, 45-50
    DOI 10.1016/j.schres.2018.08.007, PubMed 30126813

Publications 2017

  1. Fjukstad KK, Engum A, Lydersen S, Dieset I, Steen NE, Andreassen OA, Spigset O (2017)
    Metabolic risk factors in schizophrenia and bipolar disorder: The effect of comedication with selective serotonin reuptake inhibitors and antipsychotics
    Eur Psychiatry, 48, 71-78
    DOI 10.1016/j.eurpsy.2017.04.001, PubMed 29331603
  2. Iversen TSJ, Steen NE, Dieset I, Hope S, Mørch R, Gardsjord ES, Jørgensen KN, Melle I, Andreassen OA, Molden E, Jönsson EG (2017)
    Side effect burden of antipsychotic drugs in real life - Impact of gender and polypharmacy
    Prog Neuropsychopharmacol Biol Psychiatry, 82, 263-271
    DOI 10.1016/j.pnpbp.2017.11.004, PubMed 29122637
  3. Aas M, Dieset I, Hope S, Hoseth E, Mørch R, Reponen E, Steen NE, Laskemoen JF, Ueland T, Aukrust P, Agartz I, Andreassen OA, Melle I (2017)
    Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses
    Brain Behav Immun, 65, 342-349
    DOI 10.1016/j.bbi.2017.06.005, PubMed 28619247

Publications 2016

  1. Fjukstad KK, Engum A, Lydersen S, Dieset I, Steen NE, Andreassen OA, Spigset O (2016)
    Metabolic Abnormalities Related to Treatment With Selective Serotonin Reuptake Inhibitors in Patients With Schizophrenia or Bipolar Disorder
    J Clin Psychopharmacol, 36 (6), 615-620
    DOI 10.1097/JCP.0000000000000582, PubMed 27749681
  2. Steen NE, Aas M, Simonsen C, Dieset I, Tesli M, Nerhus M, Gardsjord E, Mørch R, Agartz I, Melle I, Ueland T, Spigset O, Andreassen OA (2016)
    Serum levels of second-generation antipsychotics are associated with cognitive function in psychotic disorders
    World J Biol Psychiatry, 18 (6), 471-482
    DOI 10.1080/15622975.2016.1245441, PubMed 27712130
  3. Steen NE, Aas M, Simonsen C, Dieset I, Tesli M, Nerhus M, Gardsjord E, Mørch R, Agartz I, Melle I, Vaskinn A, Spigset O, Andreassen OA (2016)
    Serum concentrations of mood stabilizers are associated with memory, but not other cognitive domains in psychosis spectrum disorders; explorative analyses in a naturalistic setting
    Int J Bipolar Disord, 4 (1), 24
    DOI 10.1186/s40345-016-0067-z, PubMed 27858347
  4. Tesli M, Wirgenes KV, Hughes T, Bettella F, Athanasiu L, Hoseth ES, Nerhus M, Lagerberg TV, Steen NE, Agartz I, Melle I, Dieset I, Djurovic S, Andreassen OA (2016)
    VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls
    Br J Psychiatry, 209 (2), 114-20
    DOI 10.1192/bjp.bp.115.161950, PubMed 26941264
  5. Aas M, Kauppi K, Brandt CL, Tesli M, Kaufmann T, Steen NE, Agartz I, Westlye LT, Andreassen OA, Melle I (2016)
    Childhood trauma is associated with increased brain responses to emotionally negative as compared with positive faces in patients with psychotic disorders
    Psychol Med, 47 (4), 669-679
    DOI 10.1017/S0033291716002762, PubMed 27834153

Publications 2015

  1. Quintana DS, Westlye LT, Kaufmann T, Rustan ØG, Brandt CL, Haatveit B, Steen NE, Andreassen OA (2015)
    Reduced heart rate variability in schizophrenia and bipolar disorder compared to healthy controls
    Acta Psychiatr Scand, 133 (1), 44-52
    DOI 10.1111/acps.12498, PubMed 26371411
  2. Steen NE, Aas M, Simonsen C, Dieset I, Tesli M, Nerhus M, Gardsjord E, Mørch R, Agartz I, Melle I, Vaskinn A, Spigset O, Andreassen OA (2015)
    Serum level of venlafaxine is associated with better memory in psychotic disorders
    Schizophr Res, 169 (1-3), 386-392
    DOI 10.1016/j.schres.2015.10.021, PubMed 26516101

Publications 2014

  1. Haram M, Tesli M, Dieset I, Steen NE, Røssberg JI, Djurovic S, Andreassen OA, Melle I (2014)
    An attempt to identify single nucleotide polymorphisms contributing to possible relationships between personality traits and oxytocin-related genes
    Neuropsychobiology, 69 (1), 25-30
    DOI 10.1159/000356965, PubMed 24458227
  2. Steen NE, Methlie P, Lorentzen S, Dieset I, Aas M, Nerhus M, Haram M, Agartz I, Melle I, Berg JP, Andreassen OA (2014)
    Altered systemic cortisol metabolism in bipolar disorder and schizophrenia spectrum disorders
    J Psychiatr Res, 52, 57-62
    DOI 10.1016/j.jpsychires.2014.01.017, PubMed 24534618

Publications 2013

  1. Hope S, Ueland T, Steen NE, Dieset I, Lorentzen S, Berg AO, Agartz I, Aukrust P, Andreassen OA (2013)
    Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia and bipolar disorder
    Schizophr Res, 145 (1-3), 36-42
    DOI 10.1016/j.schres.2012.12.023, PubMed 23403415
  2. Larsson S, Aas M, Klungsøyr O, Agartz I, Mork E, Steen NE, Barrett EA, Lagerberg TV, Røssberg JI, Melle I, Andreassen OA, Lorentzen S (2013)
    Patterns of childhood adverse events are associated with clinical characteristics of bipolar disorder
    BMC Psychiatry, 13, 97
    DOI 10.1186/1471-244X-13-97, PubMed 23522391
  3. Mork E, Walby FA, Harkavy-Friedman JM, Barrett EA, Steen NE, Lorentzen S, Andreassen OA, Melle I, Mehlum L (2013)
    Clinical characteristics in schizophrenia patients with or without suicide attempts and non-suicidal self-harm--a cross-sectional study
    BMC Psychiatry, 13, 255
    DOI 10.1186/1471-244X-13-255, PubMed 24106884
  4. Aas M, Haukvik UK, Djurovic S, Bergmann Ø, Athanasiu L, Tesli MS, Hellvin T, Steen NE, Agartz I, Lorentzen S, Sundet K, Andreassen OA, Melle I (2013)
    BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses
    Prog Neuropsychopharmacol Biol Psychiatry, 46, 181-8
    DOI 10.1016/j.pnpbp.2013.07.008, PubMed 23876786

Publications 2012

  1. Larsson S, Andreassen OA, Aas M, Røssberg JI, Mork E, Steen NE, Barrett EA, Lagerberg TV, Peleikis D, Agartz I, Melle I, Lorentzen S (2012)
    High prevalence of childhood trauma in patients with schizophrenia spectrum and affective disorder
    Compr Psychiatry, 54 (2), 123-7
    DOI 10.1016/j.comppsych.2012.06.009, PubMed 22901835
  2. Aas M, Steen NE, Agartz I, Aminoff SR, Lorentzen S, Sundet K, Andreassen OA, Melle I (2012)
    Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?
    Psychiatry Res, 198 (3), 495-500
    DOI 10.1016/j.psychres.2011.12.045, PubMed 22472845

Publications 2011

  1. Hope S, Dieset I, Agartz I, Steen NE, Ueland T, Melle I, Aukrust P, Andreassen OA (2011)
    Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia
    J Psychiatr Res, 45 (12), 1608-16
    DOI 10.1016/j.jpsychires.2011.08.003, PubMed 21889167
  2. Steen NE, Lorentzen S, Barrett EA, Lagerberg TV, Hope S, Larsson S, Berg AO, Agartz I, Melle I, Berg JP, Andreassen OA (2011)
    Sex-specific cortisol levels in bipolar disorder and schizophrenia during mental challenge--relationship to clinical characteristics and medication
    Prog Neuropsychopharmacol Biol Psychiatry, 35 (4), 1100-7
    DOI 10.1016/j.pnpbp.2011.03.008, PubMed 21420462
  3. Steen NE, Methlie P, Lorentzen S, Hope S, Barrett EA, Larsson S, Mork E, Almås B, Løvås K, Agartz I, Melle I, Berg JP, Andreassen OA (2011)
    Increased systemic cortisol metabolism in patients with schizophrenia and bipolar disorder: a mechanism for increased stress vulnerability?
    J Clin Psychiatry, 72 (11), 1515-21
    DOI 10.4088/JCP.10m06068yel, PubMed 21367348
  4. Aas M, Djurovic S, Athanasiu L, Steen NE, Agartz I, Lorentzen S, Sundet K, Andreassen OA, Melle I (2011)
    Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders
    Schizophr Bull, 38 (1), 15-22
    DOI 10.1093/schbul/sbr113, PubMed 21908796

Publications 2010

  1. Barrett EA, Sundet K, Faerden A, Agartz I, Bratlien U, Romm KL, Mork E, Rossberg JI, Steen NE, Andreassen OA, Melle I (2010)
    Suicidality in first episode psychosis is associated with insight and negative beliefs about psychosis
    Schizophr Res, 123 (2-3), 257-62
    DOI 10.1016/j.schres.2010.07.018, PubMed 20685083
  2. Barrett EA, Sundet K, Faerden A, Nesvåg R, Agartz I, Fosse R, Mork E, Steen NE, Andreassen OA, Melle I (2010)
    Suicidality before and in the early phases of first episode psychosis
    Schizophr Res, 119 (1-3), 11-7
    DOI 10.1016/j.schres.2010.03.022, PubMed 20399077
  3. Hope S, Melle I, Aukrust P, Agartz I, Lorentzen S, Steen NE, Djurovic S, Ueland T, Andreassen OA (2010)
    Osteoprotegerin levels in patients with severe mental disorders
    J Psychiatry Neurosci, 35 (5), 304-10
    DOI 10.1503/jpn.090088, PubMed 20569643
  4. Steen NE, Tesli M, Kähler AK, Methlie P, Hope S, Barrett EA, Larsson S, Mork E, Løvås K, Røssberg JI, Agartz I, Melle I, Djurovic S, Lorentzen S, Berg JP, Andreassen OA (2010)
    SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders
    Prog Neuropsychopharmacol Biol Psychiatry, 34 (8), 1500-6
    DOI 10.1016/j.pnpbp.2010.08.013, PubMed 20800085

Publications 2009

  1. Hope S, Melle I, Aukrust P, Steen NE, Birkenaes AB, Lorentzen S, Agartz I, Ueland T, Andreassen OA (2009)
    Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor
    Bipolar Disord, 11 (7), 726-34
    DOI 10.1111/j.1399-5618.2009.00757.x, PubMed 19839997
  2. Larsson S, Lorentzen S, Mork E, Barrett EA, Steen NE, Lagerberg TV, Berg AO, Aminoff SR, Agartz I, Melle I, Andreassen OA (2009)
    Age at onset of bipolar disorder in a Norwegian catchment area sample
    J Affect Disord, 124 (1-2), 174-7
    DOI 10.1016/j.jad.2009.10.031, PubMed 19931918