Bradley J. MacIntosh

  • Senior Scientist; PhD

Computational Radiology and Artificial Intelligence (CRAI)

 

Publications 2022

Dimick MK, Hird MA, Sultan AA, Mitchell RHB, Sinyor M, MacIntosh BJ, Goldstein BI (2022)
Resting-state functional connectivity indicators of risk and resilience for self-harm in adolescent bipolar disorder
Psychol Med, 1-10 (in press)
DOI 10.1017/S0033291721005419, PubMed 35256032

Dimick MK, Toma S, MacIntosh BJ, Grigorian A, Fiksenbaum L, Youngstrom EA, Robertson AD, Goldstein BI (2022)
Cerebral Blood Flow and Core Mood Symptoms in Youth Bipolar Disorder: Evidence for Region-Symptom Specificity
J Am Acad Child Adolesc Psychiatry (in press)
DOI 10.1016/j.jaac.2022.04.010, PubMed 35487335

Friedlander ANH, Mitchell RHB, Dimick MK, Kennedy KG, MacIntosh BJ, Goldstein BI (2022)
Clinical and neuroimaging characteristics of monozygotic 16-Year-Old twins discordant for bipolar disorder: A case study
Bipolar Disord (in press)
DOI 10.1111/bdi.13258, PubMed 36117325

Grigorian A, Kennedy KG, Luciw NJ, MacIntosh BJ, Goldstein BI (2022)
Obesity and Cerebral Blood Flow in the Reward Circuitry of Youth With Bipolar Disorder
Int J Neuropsychopharmacol, 25 (6), 448-456
DOI 10.1093/ijnp/pyac011, PubMed 35092432

Kim WSH, Luciw NJ, Atwi S, Shirzadi Z, Dolui S, Detre JA, Nasrallah IM, Swardfager W, Bryan RN, Launer LJ, MacIntosh BJ (2022)
Associations of white matter hyperintensities with networks of gray matter blood flow and volume in midlife adults: A coronary artery risk development in young adults magnetic resonance imaging substudy
Hum Brain Mapp, 43 (12), 3680-3693
DOI 10.1002/hbm.25876, PubMed 35429100

Lee H, Ozturk B, Stringer MS, Koundal S, MacIntosh BJ, Rothman D, Benveniste H (2022)
Choroid plexus tissue perfusion and blood to CSF barrier function in rats measured with continuous arterial spin labeling
Neuroimage, 261, 119512
DOI 10.1016/j.neuroimage.2022.119512, PubMed 35882269

Liew SL, Lo BP, Donnelly MR, Zavaliangos-Petropulu A, Jeong JN, Barisano G, Hutton A, Simon JP, Juliano JM, Suri A, Wang Z, Abdullah A, Kim J, Ard T, Banaj N, Borich MR, Boyd LA, Brodtmann A, Buetefisch CM, Cao L, Cassidy JM, Ciullo V, Conforto AB, Cramer SC, Dacosta-Aguayo R et al. (2022)
A large, curated, open-source stroke neuroimaging dataset to improve lesion segmentation algorithms
Sci Data, 9 (1), 320
DOI 10.1038/s41597-022-01401-7, PubMed 35710678

Luciw NJ, Shirzadi Z, Black SE, Goubran M, MacIntosh BJ (2022)
Automated generation of cerebral blood flow and arterial transit time maps from multiple delay arterial spin-labeled MRI
Magn Reson Med, 88 (1), 406-417
DOI 10.1002/mrm.29193, PubMed 35181925

Mio M, Grigorian A, Zou Y, Dimick MK, Selkirk B, Kertes P, McCrindle BW, Swardfager W, Hahn MK, Black SE, MacIntosh BJ, Goldstein BI (2022)
Neurovascular correlates of retinal microvascular caliber in adolescent bipolar disorder
J Affect Disord (in press)
DOI 10.1016/j.jad.2022.09.082, PubMed 36162693

Misquitta K, Daou M, Conklin J, Liao C, Setsompop K, Poublanc J, Shirzadi Z, MacIntosh BJ, Tomlinson G, Cohn M, Aviv RI, Silver FL, Mandell DM (2022)
Detecting Silent Acute Microinfarcts in Cerebral Small Vessel Disease Using Submillimeter Diffusion-Weighted Magnetic Resonance Imaging: Preliminary Results
Stroke, 53 (7), e251-e252
DOI 10.1161/STROKEAHA.122.039723, PubMed 35695007

Pasternak M, Shirzadi Z, Mutsaerts HJMM, Boot E, Butcher NJ, MacIntosh BJ, Heung T, Bassett AS, Masellis M (2022)
Elevated regional cerebral blood flow in adults with 22q11.2 deletion syndrome
World J Biol Psychiatry, 1-6 (in press)
DOI 10.1080/15622975.2022.2093969, PubMed 35748435

Roane JL, Mio M, Viner J, Bettridge A, Heyn C, Roifman I, Selkirk B, Kertes P, MacIntosh BJ, Thayalasuthan V, Detzler G, Endre R, Jimenez-Juan L, Henry B, Murray BJ, Goldstein BI (2022)
Incidental Findings Among Youth Participating in Multimodal Imaging Research: Characteristics of Findings and Description of a Management Approach
Front Pediatr, 10, 875934
DOI 10.3389/fped.2022.875934, PubMed 35813368

Simpson LA, Barclay R, Bayley MT, Dukelow SP, MacIntosh BJ, MacKay-Lyons M, Menon C, Mortenson WB, Peng TH, Pollock CL, Pooyania S, Teasell R, Yang CL, Yao J, Eng JJ (2022)
Virtual Arm Boot Camp (V-ABC): study protocol for a mixed-methods study to increase upper limb recovery after stroke with an intensive program coupled with a grasp count device
Trials, 23 (1), 129
DOI 10.1186/s13063-022-06047-9, PubMed 35135585

Simpson LA, Barclay R, Bayley MT, Dukelow SP, MacIntosh BJ, MacKay-Lyons M, Menon C, Mortenson WB, Peng TH, Pollock CL, Pooyania S, Teasell R, Yang CL, Yao J, Eng JJ (2022)
Correction: Virtual Arm Boot Camp (V-ABC): study protocol for a mixed-methods study to increase upper limb recovery after stroke with an intensive program coupled with a grasp count device
Trials, 23 (1), 207
DOI 10.1186/s13063-022-06134-x, PubMed 35277187

Wu CY, Shapiro L, Ouk M, MacIntosh BJ, Black SE, Shah BR, Swardfager W (2022)
Glucose-lowering drugs, cognition, and dementia: The clinical evidence
Neurosci Biobehav Rev, 137, 104654
DOI 10.1016/j.neubiorev.2022.104654, PubMed 35398114

Zavaliangos-Petropulu A, Lo B, Donnelly MR, Schweighofer N, Lohse K, Jahanshad N, Barisano G, Banaj N, Borich MR, Boyd LA, Buetefisch CM, Byblow WD, Cassidy JM, Charalambous CC, Conforto AB, DiCarlo JA, Dula AN, Egorova-Brumley N, Etherton MR, Feng W, Fercho KA, Geranmayeh F, Hanlon CA, Hayward KS, Hordacre B et al. (2022)
Chronic Stroke Sensorimotor Impairment Is Related to Smaller Hippocampal Volumes: An ENIGMA Analysis
J Am Heart Assoc, 11 (10), e025109
DOI 10.1161/JAHA.121.025109, PubMed 35574963

Zou Y, Kennedy KG, Grigorian A, Fiksenbaum L, Freeman N, Zai CC, Kennedy JL, MacIntosh BJ, Goldstein BI (2022)
Antioxidative Defense Genes and Brain Structure in Youth Bipolar Disorder
Int J Neuropsychopharmacol, 25 (2), 89-98
DOI 10.1093/ijnp/pyab056, PubMed 34387669

Publications 2021

Atwi S, Sweeny M, Cohen E, Robertson AD, Marzolini S, Swardfager W, Swartz RH, Oh PI, MacIntosh BJ (2021)
Cerebrovascular assessments to help understand brain-related changes associated with aerobic exercise after stroke
Appl Physiol Nutr Metab, 46 (4), 412-415
DOI 10.1139/apnm-2020-0228, PubMed 33400620

Cazes J, Dimick MK, Kennedy KG, Fiksenbaum L, Zai CC, Patel R, Islam AH, Tampakeras M, Freeman N, Kennedy JL, MacIntosh BJ, Goldstein BI (2021)
Structural neuroimaging phenotypes of a novel multi-gene risk score in youth bipolar disorder
J Affect Disord, 289, 135-143
DOI 10.1016/j.jad.2021.04.040, PubMed 33979723

Dimick MK, Kennedy KG, Mitchell RHB, Sinyor M, MacIntosh BJ, Goldstein BI (2021)
Neurostructural differences associated with self-harm in youth bipolar disorder
Bipolar Disord, 24 (3), 275-285
DOI 10.1111/bdi.13137, PubMed 34596314

Goldstein BI, MacIntosh BJ (2021)
The unrealized promise of cerebrovascular magnetic resonance imaging in psychiatric research across the lifespan
Eur Neuropsychopharmacol, 55, 11-13
DOI 10.1016/j.euroneuro.2021.10.862, PubMed 34749052

Kennedy KG, Grigorian A, Mitchell RHB, McCrindle BW, MacIntosh BJ, Goldstein BI (2021)
Association of blood pressure with brain structure in youth with and without bipolar disorder
J Affect Disord, 299, 666-674
DOI 10.1016/j.jad.2021.12.028, PubMed 34920038

Kennedy KG, Islam AH, Grigorian A, Fiksenbaum L, Mitchell RHB, McCrindle BW, MacIntosh BJ, Goldstein BI (2021)
Elevated lipids are associated with reduced regional brain structure in youth with bipolar disorder
Acta Psychiatr Scand, 143 (6), 513-525
DOI 10.1111/acps.13278, PubMed 33492669

Kennedy KG, Shahatit Z, Dimick MK, Fiksenbaum L, Freeman N, Zai CC, Kennedy JL, MacIntosh BJ, Goldstein BI (2021)
Neurostructural correlates of BDNF rs6265 genotype in youth bipolar disorder
Bipolar Disord, 24 (2), 185-194
DOI 10.1111/bdi.13116, PubMed 34263997

Liew SL, Zavaliangos-Petropulu A, Schweighofer N, Jahanshad N, Lang CE, Lohse KR, Banaj N, Barisano G, Baugh LA, Bhattacharya AK, Bigjahan B, Borich MR, Boyd LA, Brodtmann A, Buetefisch CM, Byblow WD, Cassidy JM, Charalambous CC, Ciullo V, Conforto AB, Craddock RC, Dula AN, Egorova N, Feng W, Fercho KA et al. (2021)
Smaller spared subcortical nuclei are associated with worse post-stroke sensorimotor outcomes in 28 cohorts worldwide
Brain Commun, 3 (4), fcab254
DOI 10.1093/braincomms/fcab254, PubMed 34805997

Lin Z, Tam F, Churchill NW, Lin FH, MacIntosh BJ, Schweizer TA, Graham SJ (2021)
Trail Making Test Performance Using a Touch-Sensitive Tablet: Behavioral Kinematics and Electroencephalography
Front Hum Neurosci, 15, 663463
DOI 10.3389/fnhum.2021.663463, PubMed 34276323

Luciw NJ, Toma S, Goldstein BI, MacIntosh BJ (2021)
Correspondence between patterns of cerebral blood flow and structure in adolescents with and without bipolar disorder
J Cereb Blood Flow Metab, 41 (8), 1988-1999
DOI 10.1177/0271678X21989246, PubMed 33487070

MacIntosh BJ, Cohen E, Colby-Milley J, Fang J, Zhou L, Ouk M, Wu CY, Shah BR, Lanctôt K, Herrmann N, Linkewich E, Law M, Black SE, Swartz RH, Kapral MK, Edwards JD, Swardfager W (2021)
Diabetes Mellitus Is Associated With Poor In-Hospital and Long-Term Outcomes in Young and Midlife Stroke Survivors
J Am Heart Assoc, 10 (14), e019991
DOI 10.1161/JAHA.120.019991, PubMed 34219470

MacIntosh BJ, Ji X, Chen JJ, Gilboa A, Roudaia E, Sekuler AB, Gao F, Chad JA, Jegatheesan A, Masellis M, Goubran M, Rabin J, Lam B, Cheng I, Fowler R, Heyn C, Black SE, Graham SJ (2021)
Brain structure and function in people recovering from COVID-19 after hospital discharge or self-isolation: a longitudinal observational study protocol
CMAJ Open, 9 (4), E1114-E1119
DOI 10.9778/cmajo.20210023, PubMed 34848552

Mehrhof SZ, Popel N, Mio M, Lu W, Heyn CC, Fiksenbaum LM, MacIntosh BJ, Goldstein BI (2021)
Prevalence of white matter hyperintensities is not elevated in a large sample of adolescents and young adults with bipolar disorder
Braz J Psychiatry, 43 (2), 147-152
DOI 10.1590/1516-4446-2020-0886, PubMed 32785453

Shakeel MK, Hassel S, Davis AD, Metzak PD, MacQueen GM, Arnott SR, Bray S, Frey BN, Goldstein BI, Hall GB, Harris J, Lam RW, MacIntosh BJ, Milev R, Mueller DJ, Rotzinger S, Strother SC, Wang J, Zamyadi M, Kennedy SH, Addington J, Lebel C (2021)
White matter microstructure in youth at risk for serious mental illness: A comparative analysis
Psychiatry Res Neuroimaging, 312, 111289
DOI 10.1016/j.pscychresns.2021.111289, PubMed 33910139

Sultan AA, Hird MA, Dimick MK, MacIntosh BJ, Goldstein BI (2021)
Cannabis use and resting state functional connectivity in adolescent bipolar disorder
J Psychiatry Neurosci, 46 (5), E559-E567
DOI 10.1503/jpn.200228, PubMed 34625488

Sultan AA, Kennedy KG, Fiksenbaum L, MacIntosh BJ, Goldstein BI (2021)
Neurostructural Correlates of Cannabis Use in Adolescent Bipolar Disorder
Int J Neuropsychopharmacol, 24 (3), 181-190
DOI 10.1093/ijnp/pyaa077, PubMed 33103721

Publications 2020

Ayoub R, Ruddy RM, Cox E, Oyefiade A, Derkach D, Laughlin S, Ades-Aron B, Shirzadi Z, Fieremans E, MacIntosh BJ, de Medeiros CB, Skocic J, Bouffet E, Miller FD, Morshead CM, Mabbott DJ (2020)
Assessment of cognitive and neural recovery in survivors of pediatric brain tumors in a pilot clinical trial using metformin
Nat Med, 26 (8), 1285-1294
DOI 10.1038/s41591-020-0985-2, PubMed 32719487

Ching CRK, Hibar DP, Gurholt TP, Nunes A, Thomopoulos SI, Abé C, Agartz I, Brouwer RM, Cannon DM, de Zwarte SMC, Eyler LT, Favre P, Hajek T, Haukvik UK, Houenou J, Landén M, Lett TA, McDonald C, Nabulsi L, Patel Y, Pauling ME, Paus T, Radua J, Soeiro-de-Souza MG, Tronchin G et al. (2020)
What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 56-82
DOI 10.1002/hbm.25098, PubMed 32725849

Cogo-Moreira H, Krance SH, Black SE, Herrmann N, Lanctôt KL, MacIntosh BJ, Eid M, Swardfager W (2020)
Questioning the Meaning of a Change on the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog): Noncomparable Scores and Item-Specific Effects Over Time
Assessment, 28 (6), 1708-1722
DOI 10.1177/1073191120915273, PubMed 32406251

Dimick MK, Omrin D, MacIntosh BJ, Mitchell RHB, Riegert D, Levitt A, Schaffer A, Belo S, Iazzetta J, Detzler G, Choi M, Choi S, Orser BA, Goldstein BI (2020)
Nitrous oxide as a putative novel dual-mechanism treatment for bipolar depression: Proof-of-concept study design and methodology
Contemp Clin Trials Commun, 19, 100600
DOI 10.1016/j.conctc.2020.100600, PubMed 32637725

Gurholt TP, Lonning V, Nerland S, Jørgensen KN, Haukvik UK, Alloza C, Arango C, Barth C, Bearden CE, Berk M, Bohman H, Dandash O, Díaz-Caneja CM, Edbom CT, van Erp TGM, Fett AJ, Frangou S, Goldstein BI, Grigorian A, Jahanshad N, James AC, Janssen J, Johannessen C, Karlsgodt KH, Kempton MJ et al. (2020)
Intracranial and subcortical volumes in adolescents with early-onset psychosis: A multisite mega-analysis from the ENIGMA consortium
Hum Brain Mapp, 43 (1), 373-384
DOI 10.1002/hbm.25212, PubMed 33017498

Hussein A, Matthews JL, Syme C, Macgowan C, MacIntosh BJ, Shirzadi Z, Pausova Z, Paus T, Chen JJ (2020)
The association between resting-state functional magnetic resonance imaging and aortic pulse-wave velocity in healthy adults
Hum Brain Mapp, 41 (8), 2121-2135
DOI 10.1002/hbm.24934, PubMed 32034832

Koblinsky ND, Atwi S, Cohen E, Anderson ND, Greenwood CE, MacIntosh BJ, Robertson AD (2020)
Lower Thalamic Blood Flow Is Associated With Slower Stride Velocity in Older Adults
Front Aging Neurosci, 12, 571074
DOI 10.3389/fnagi.2020.571074, PubMed 33192462

Liew SL, Zavaliangos-Petropulu A, Jahanshad N, Lang CE, Hayward KS, Lohse KR, Juliano JM, Assogna F, Baugh LA, Bhattacharya AK, Bigjahan B, Borich MR, Boyd LA, Brodtmann A, Buetefisch CM, Byblow WD, Cassidy JM, Conforto AB, Craddock RC, Dimyan MA, Dula AN, Ermer E, Etherton MR, Fercho KA, Gregory CM et al. (2020)
The ENIGMA Stroke Recovery Working Group: Big data neuroimaging to study brain-behavior relationships after stroke
Hum Brain Mapp, 43 (1), 129-148
DOI 10.1002/hbm.25015, PubMed 32310331

Metzak PD, Addington J, Hassel S, Goldstein BI, MacIntosh BJ, Lebel C, Wang JL, Kennedy SH, MacQueen GM, Bray S (2020)
Functional imaging in youth at risk for transdiagnostic serious mental illness: Initial results from the PROCAN study
Early Interv Psychiatry, 15 (5), 1276-1291
DOI 10.1111/eip.13078, PubMed 33295151

Mutsaerts HJMM, Petr J, Groot P, Vandemaele P, Ingala S, Robertson AD, Václavů L, Groote I, Kuijf H, Zelaya F, O'Daly O, Hilal S, Wink AM, Kant I, Caan MWA, Morgan C, de Bresser J, Lysvik E, Schrantee A, Bjørnebekk A, Clement P, Shirzadi Z, Kuijer JPA, Wottschel V, Anazodo UC et al. (2020)
ExploreASL: An image processing pipeline for multi-center ASL perfusion MRI studies
Neuroimage, 219, 117031
DOI 10.1016/j.neuroimage.2020.117031, PubMed 32526385

Nogovitsyn N, Souza R, Muller M, Srajer A, Metzak PD, Hassel S, Ismail Z, Protzner A, Bray SL, Lebel C, MacIntosh BJ, Goldstein BI, Wang J, Kennedy SH, Addington J, MacQueen GM (2020)
Aberrant limbic brain structures in young individuals at risk for mental illness
Psychiatry Clin Neurosci, 74 (5), 294-302
DOI 10.1111/pcn.12985, PubMed 32003517

Ouk M, Wu CY, Colby-Milley J, Fang J, Zhou L, Shah BR, Herrmann N, Lanctôt KL, Linkewich E, Law M, Swartz RH, Kapral MK, Black SE, MacIntosh BJ, Edwards JD, Swardfager W (2020)
Depression and Diabetes Mellitus Multimorbidity Is Associated With Loss of Independence and Dementia Poststroke
Stroke, 51 (12), 3531-3540
DOI 10.1161/STROKEAHA.120.031068, PubMed 33226916

Popel N, Kennedy KG, Fiksenbaum L, Mitchell RHB, MacIntosh BJ, Goldstein BI (2020)
Clinical and neuroimaging correlates of cardiorespiratory fitness in adolescents with bipolar disorder
Bipolar Disord, 23 (3), 274-283
DOI 10.1111/bdi.12993, PubMed 32960499

Rabin JS, Shirzadi Z, Swardfager W, MacIntosh BJ, Schultz A, Yang HS, Buckley RF, Gatchel JR, Kirn D, Pruzin JJ, Hedden T, Lipsman N, Rentz DM, Black SE, Johnson KA, Sperling RA, Chhatwal JP, Harvard Aging Brain Study, Alzheimer's Disease Neuroimaging Initiative (2020)
Amyloid-beta burden predicts prospective decline in body mass index in clinically normal adults
Neurobiol Aging, 93, 124-130
DOI 10.1016/j.neurobiolaging.2020.03.002, PubMed 32249013

Shakeel MK, MacQueen G, Addington J, Metzak PD, Georgopoulos G, Bray S, Goldstein BI, MacIntosh BJ, Wang J, Kennedy SH, Lebel C (2020)
White Matter Connectivity in Youth at Risk for Serious Mental Illness: A Longitudinal Analysis
Psychiatry Res Neuroimaging, 302, 111106
DOI 10.1016/j.pscychresns.2020.111106, PubMed 32505905

Shonibare DO, Patel RR, Islam AH, Metcalfe AWS, Fiksenbaum L, Freeman N, MacIntosh BJ, Kennedy JL, Goldstein BI (2020)
Neurostructural phenotypes of CACNA1C rs1006737 in adolescents with bipolar disorder and healthy controls
Prog Neuropsychopharmacol Biol Psychiatry, 104, 110071
DOI 10.1016/j.pnpbp.2020.110071, PubMed 32800865

Stringer MS, Lee H, Huuskonen MT, MacIntosh BJ, Brown R, Montagne A, Atwi S, Ramirez J, Jansen MA, Marshall I, Black SE, Zlokovic BV, Benveniste H, Wardlaw JM (2020)
A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease
Transl Stroke Res, 12 (1), 15-30
DOI 10.1007/s12975-020-00843-8, PubMed 32936435

van Dalen JW, Mutsaerts HJ, Petr J, Caan MW, van Charante EPM, MacIntosh BJ, van Gool WA, Nederveen AJ, Richard E (2020)
Longitudinal relation between blood pressure, antihypertensive use and cerebral blood flow, using arterial spin labelling MRI
J Cereb Blood Flow Metab, 41 (7), 1756-1766
DOI 10.1177/0271678X20966975, PubMed 33325767

Wardlaw JM, Benveniste H, Nedergaard M, Zlokovic BV, Mestre H, Lee H, Doubal FN, Brown R, Ramirez J, MacIntosh BJ, Tannenbaum A, Ballerini L, Rungta RL, Boido D, Sweeney M, Montagne A, Charpak S, Joutel A, Smith KJ, Black SE, colleagues from the Fondation Leducq Transatlantic Network of Excellence on the Role of the Perivascular Space in Cerebral Small Vessel Disease (2020)
Perivascular spaces in the brain: anatomy, physiology and pathology
Nat Rev Neurol, 16 (3), 137-153
DOI 10.1038/s41582-020-0312-z, PubMed 32094487

Wu CY, Ouk M, Wong YY, Anita NZ, Edwards JD, Yang P, Shah BR, Herrmann N, Lanctôt KL, Kapral MK, MacIntosh BJ, Rabin JS, Black SE, Swardfager W (2020)
Relationships between memory decline and the use of metformin or DPP4 inhibitors in people with type 2 diabetes with normal cognition or Alzheimer's disease, and the role APOE carrier status
Alzheimers Dement, 16 (12), 1663-1673
DOI 10.1002/alz.12161, PubMed 32803865

Publications 2019

Atwi S, Robertson AD, Theyers AE, Ramirez J, Swartz RH, Marzolini S, MacIntosh BJ (2019)
Cardiac-Related Pulsatility in the Insula Is Directly Associated With Middle Cerebral Artery Pulsatility Index
J Magn Reson Imaging, 51 (5), 1454-1462
DOI 10.1002/jmri.26950, PubMed 31667941

Atwi S, Shao H, Crane DE, da Costa L, Aviv RI, Mikulis DJ, Black SE, MacIntosh BJ (2019)
BOLD-based cerebrovascular reactivity vascular transfer function isolates amplitude and timing responses to better characterize cerebral small vessel disease
NMR Biomed, 32 (3), e4064
DOI 10.1002/nbm.4064, PubMed 30693582

Karthikeyan S, Fiksenbaum L, Grigorian A, Lu H, MacIntosh BJ, Goldstein BI (2019)
Normal Cerebral Oxygen Consumption Despite Elevated Cerebral Blood Flow in Adolescents With Bipolar Disorder: Putative Neuroimaging Evidence of Anomalous Energy Metabolism
Front Psychiatry, 10, 739
DOI 10.3389/fpsyt.2019.00739, PubMed 31681045

Kostoglou K, Robertson AD, MacIntosh BJ, Mitsis GD (2019)
A Novel Framework for Estimating Time-Varying Multivariate Autoregressive Models and Application to Cardiovascular Responses to Acute Exercise
IEEE Trans Biomed Eng, 66 (11), 3257-3266
DOI 10.1109/TBME.2019.2903012, PubMed 30843796

MacIntosh BJ, Shirzadi Z, Atwi S, Detre JA, Dolui S, Bryan RN, Launer LJ, Swardfager W (2019)
Metabolic and vascular risk factors are associated with reduced cerebral blood flow and poorer midlife memory performance
Hum Brain Mapp, 41 (4), 855-864
DOI 10.1002/hbm.24844, PubMed 31651075

Marzolini S, Robertson AD, Oh P, Goodman JM, Corbett D, Du X, MacIntosh BJ (2019)
Aerobic Training and Mobilization Early Post-stroke: Cautions and Considerations
Front Neurol, 10, 1187
DOI 10.3389/fneur.2019.01187, PubMed 31803129

Meng Y, MacIntosh BJ, Shirzadi Z, Kiss A, Bethune A, Heyn C, Mithani K, Hamani C, Black SE, Hynynen K, Lipsman N (2019)
Resting state functional connectivity changes after MR-guided focused ultrasound mediated blood-brain barrier opening in patients with Alzheimer's disease
Neuroimage, 200, 275-280
DOI 10.1016/j.neuroimage.2019.06.060, PubMed 31254646

Meusel LC, Greenwood CE, Maione A, Tchistiakova E, MacIntosh BJ, Anderson ND (2019)
Cardiovascular risk and encoding-related hippocampal connectivity in older adults
BMC Neurosci, 20 (1), 37
DOI 10.1186/s12868-019-0518-4, PubMed 31366391

Mutsaerts HJMM, Mirza SS, Petr J, Thomas DL, Cash DM, Bocchetta M, de Vita E, Metcalfe AWS, Shirzadi Z, Robertson AD, Tartaglia MC, Mitchell SB, Black SE, Freedman M, Tang-Wai D, Keren R, Rogaeva E, van Swieten J, Laforce R, Tagliavini F, Borroni B, Galimberti D, Rowe JB, Graff C, Frisoni GB et al. (2019)
Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study
Brain, 142 (4), 1108-1120
DOI 10.1093/brain/awz039, PubMed 30847466

Robertson AD, Atwi S, Kostoglou K, Verhoeff NPLG, Oh PI, Mitsis GD, Marzolini S, MacIntosh BJ (2019)
Cerebrovascular Pulsatility During Rest and Exercise Reflects Hemodynamic Impairment in Stroke and Cerebral Small Vessel Disease
Ultrasound Med Biol, 45 (12), 3116-3127
DOI 10.1016/j.ultrasmedbio.2019.08.019, PubMed 31570171

Shirzadi Z, Stefanovic B, Mutsaerts HJMM, Masellis M, MacIntosh BJ, Alzheimer's Disease Neuroimaging Initiative (2019)
Classifying cognitive impairment based on the spatial heterogeneity of cerebral blood flow images
J Magn Reson Imaging, 50 (3), 858-867
DOI 10.1002/jmri.26650, PubMed 30666734

Shonibare DO, Patel R, Islam AH, Metcalfe AWS, Fiksenbaum L, Kennedy JL, Freeman N, MacIntosh BJ, Goldstein BI (2019)
Preliminary study of structural magnetic resonance imaging phenotypes related to genetic variation in Interleukin-1β rs16944 in adolescents with Bipolar Disorder
J Psychiatr Res, 122, 33-41
DOI 10.1016/j.jpsychires.2019.12.018, PubMed 31918351

Smith EE, Biessels GJ, De Guio F, de Leeuw FE, Duchesne S, Düring M, Frayne R, Ikram MA, Jouvent E, MacIntosh BJ, Thrippleton MJ, Vernooij MW, Adams H, Backes WH, Ballerini L, Black SE, Chen C, Corriveau R, DeCarli C, Greenberg SM, Gurol ME, Ingrisch M, Job D, Lam BYK, Launer LJ et al. (2019)
Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration
Alzheimers Dement (Amst), 11, 191-204
DOI 10.1016/j.dadm.2019.01.002, PubMed 30859119

Publications 2018

Atwi S, Metcalfe AWS, Robertson AD, Rezmovitz J, Anderson ND, MacIntosh BJ (2018)
Attention-Related Brain Activation Is Altered in Older Adults With White Matter Hyperintensities Using Multi-Echo fMRI
Front Neurosci, 12, 748
DOI 10.3389/fnins.2018.00748, PubMed 30405336

Ballerini L, Lovreglio R, Valdés Hernández MDC, Ramirez J, MacIntosh BJ, Black SE, Wardlaw JM (2018)
Perivascular Spaces Segmentation in Brain MRI Using Optimal 3D Filtering
Sci Rep, 8 (1), 2132
DOI 10.1038/s41598-018-19781-5, PubMed 29391404

Islam AH, Metcalfe AWS, MacIntosh BJ, Korczak DJ, Goldstein BI (2018)
Greater body mass index is associated with reduced frontal cortical volumes among adolescents with bipolar disorder
J Psychiatry Neurosci, 43 (2), 120-130
PubMed 29481319

Marzolini S, Brooks D, Oh P, Jagroop D, MacIntosh BJ, Anderson ND, Alter D, Corbett D (2018)
Aerobic With Resistance Training or Aerobic Training Alone Poststroke: A Secondary Analysis From a Randomized Clinical Trial
Neurorehabil Neural Repair, 32 (3), 209-222
DOI 10.1177/1545968318765692, PubMed 29600726

Mitchell RH, Metcalfe AW, Islam AH, Toma S, Patel R, Fiksenbaum L, Korczak D, MacIntosh BJ, Goldstein BI (2018)
Sex differences in brain structure among adolescents with bipolar disorder
Bipolar Disord (in press)
DOI 10.1111/bdi.12663, PubMed 29956452

Saeed U, Mirza SS, MacIntosh BJ, Herrmann N, Keith J, Ramirez J, Nestor SM, Yu Q, Knight J, Swardfager W, Potkin SG, Rogaeva E, St George-Hyslop P, Black SE, Masellis M (2018)
APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies
Alzheimers Dement, 14 (9), 1137-1147
DOI 10.1016/j.jalz.2018.04.005, PubMed 29782824

Shirzadi Z, Robertson AD, Metcalfe AW, Duff-Canning S, Marras C, Lang AE, Masellis M, MacIntosh BJ (2018)
Brain tissue pulsatility is related to clinical features of Parkinson's disease
Neuroimage Clin, 20, 222-227
DOI 10.1016/j.nicl.2018.07.017, PubMed 30090696

Theyers AE, Goldstein BI, Metcalfe AW, Robertson AD, MacIntosh BJ (2018)
Cerebrovascular blood oxygenation level dependent pulsatility at baseline and following acute exercise among healthy adolescents
J Cereb Blood Flow Metab, 39 (9), 1737-1749
DOI 10.1177/0271678X18766771, PubMed 29561225

Toma S, Islam AH, Metcalfe AWS, Mitchell RHB, Fiksenbaum L, MacIntosh BJ, Goldstein BI (2018)
Cortical Volume and Thickness Across Bipolar Disorder Subtypes in Adolescents: A Preliminary Study
J Child Adolesc Psychopharmacol, 29 (2), 141-151
DOI 10.1089/cap.2017.0137, PubMed 30359542

Toma S, MacIntosh BJ, Swardfager W, Goldstein BI (2018)
Cerebral blood flow in bipolar disorder: A systematic review
J Affect Disord, 241, 505-513
DOI 10.1016/j.jad.2018.08.040, PubMed 30149339

Urback AL, Metcalfe AW, Korczak DJ, MacIntosh BJ, Goldstein BI (2018)
Reduced cerebrovascular reactivity among adolescents with bipolar disorder
Bipolar Disord, 21 (2), 124-131
DOI 10.1111/bdi.12719, PubMed 30422372

Urback AL, Metcalfe AWS, Korczak DJ, MacIntosh BJ, Goldstein BI (2018)
Magnetic resonance imaging of cerebrovascular reactivity in healthy adolescents
J Neurosci Methods, 306, 1-9
DOI 10.1016/j.jneumeth.2018.06.001, PubMed 29879447

Publications 2017

Islam AH, Metcalfe AWS, MacIntosh BJ, Korczak DJ, Goldstein BI (2017)
Greater body mass index is associated with reduced frontal cortical volumes among adolescents with bipolar disorder
J Psychiatry Neurosci, 43 (1), 170041 (in press)
DOI 10.1503/jpn.170041, PubMed 29077553

MacIntosh BJ, Edwards JD, Kang M, Cogo-Moreira H, Chen JL, Mochizuki G, Herrmann N, Swardfager W (2017)
Post-stroke Fatigue and Depressive Symptoms Are Differentially Related to Mobility and Cognitive Performance
Front Aging Neurosci, 9, 343
DOI 10.3389/fnagi.2017.00343, PubMed 29163127

Mutsaerts HJ, Petr J, Václavů L, van Dalen JW, Robertson AD, Caan MW, Masellis M, Nederveen AJ, Richard E, MacIntosh BJ (2017)
The spatial coefficient of variation in arterial spin labeling cerebral blood flow images
J Cereb Blood Flow Metab, 37 (9), 3184-3192
DOI 10.1177/0271678X16683690, PubMed 28058975

Mutsaerts HJMM, Petr J, Thomas DL, De Vita E, Cash DM, van Osch MJP, Golay X, Groot PFC, Ourselin S, van Swieten J, Laforce R, Tagliavini F, Borroni B, Galimberti D, Rowe JB, Graff C, Pizzini FB, Finger E, Sorbi S, Castelo Branco M, Rohrer JD, Masellis M, MacIntosh BJ, GENFI investigators (2017)
Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI)
J Magn Reson Imaging, 47 (1), 131-140
DOI 10.1002/jmri.25751, PubMed 28480617

Robertson AD, Marzolini S, Middleton LE, Basile VS, Oh PI, MacIntosh BJ (2017)
Exercise Training Increases Parietal Lobe Cerebral Blood Flow in Chronic Stroke: An Observational Study
Front Aging Neurosci, 9, 318
DOI 10.3389/fnagi.2017.00318, PubMed 29033829

Shirzadi Z, Stefanovic B, Chappell MA, Ramirez J, Schwindt G, Masellis M, Black SE, MacIntosh BJ (2017)
Enhancement of automated blood flow estimates (ENABLE) from arterial spin-labeled MRI
J Magn Reson Imaging, 47 (3), 647-655
DOI 10.1002/jmri.25807, PubMed 28681479

Urback AL, MacIntosh BJ, Goldstein BI (2017)
Cerebrovascular reactivity measured by functional magnetic resonance imaging during breath-hold challenge: A systematic review
Neurosci Biobehav Rev, 79, 27-47
DOI 10.1016/j.neubiorev.2017.05.003, PubMed 28487157

Publications 2016

Hojjat SP, Cantrell CG, Vitorino R, Feinstein A, Shirzadi Z, MacIntosh BJ, Crane DE, Zhang L, Morrow SA, Lee L, O'Connor P, Carroll TJ, Aviv RI (2016)
Regional reduction in cortical blood flow among cognitively impaired adults with relapsing-remitting multiple sclerosis patients
Mult Scler, 22 (11), 1421-1428
DOI 10.1177/1352458515622696, PubMed 26754799

MacIntosh BJ, Shirzadi Z, Scavone A, Metcalfe AW, Islam AH, Korczak D, Goldstein BI (2016)
Increased cerebral blood flow among adolescents with bipolar disorder at rest is reduced following acute aerobic exercise
J Affect Disord, 208, 205-213
DOI 10.1016/j.jad.2016.08.060, PubMed 27792964

Marzolini S, Oh P, Corbett D, Dooks D, Calouro M, MacIntosh BJ, Goodman R, Brooks D (2016)
Prescribing Aerobic Exercise Intensity without a Cardiopulmonary Exercise Test Post Stroke: Utility of the Six-Minute Walk Test
J Stroke Cerebrovasc Dis, 25 (9), 2222-31
DOI 10.1016/j.jstrokecerebrovasdis.2016.04.016, PubMed 27289183

Meusel LC, Anderson ND, Parrott MD, Yuen W, Tchistiakova E, MacIntosh BJ, Feldman S, Greenwood CE (2016)
Brain Function Is Linked to LDL Cholesterol in Older Adults with Cardiovascular Risk
J Am Geriatr Soc, 65 (2), e51-e55
DOI 10.1111/jgs.14663, PubMed 27869302

Ssali T, Anazodo UC, Bureau Y, MacIntosh BJ, Günther M, St Lawrence K (2016)
Mapping Long-Term Functional Changes in Cerebral Blood Flow by Arterial Spin Labeling
PLoS One, 11 (10), e0164112
DOI 10.1371/journal.pone.0164112, PubMed 27706218

Swardfager W, MacIntosh BJ (2016)
Depression, Type 2 Diabetes, and Poststroke Cognitive Impairment
Neurorehabil Neural Repair, 31 (1), 48-55
DOI 10.1177/1545968316656054, PubMed 27364648

Tchistiakova E, MacIntosh BJ, Alzheimer's Disease Neuroimaging Initiative (2016)
Summative effects of vascular risk factors on cortical thickness in mild cognitive impairment
Neurobiol Aging, 45, 98-106
DOI 10.1016/j.neurobiolaging.2016.05.011, PubMed 27459930

Udow SJ, Robertson AD, MacIntosh BJ, Espay AJ, Rowe JB, Lang AE, Masellis M (2016)
'Under pressure': is there a link between orthostatic hypotension and cognitive impairment in α-synucleinopathies?
J Neurol Neurosurg Psychiatry, 87 (12), 1311-1321
DOI 10.1136/jnnp-2016-314123, PubMed 27613160

Publications 2015

Crane DE, Black SE, Ganda A, Mikulis DJ, Nestor SM, Donahue MJ, MacIntosh BJ (2015)
Gray matter blood flow and volume are reduced in association with white matter hyperintensity lesion burden: a cross-sectional MRI study
Front Aging Neurosci, 7, 131
DOI 10.3389/fnagi.2015.00131, PubMed 26217223

Makedonov I, Chen JJ, Masellis M, MacIntosh BJ, Alzheimer's Disease Neuroimaging Initiative (2015)
Physiological fluctuations in white matter are increased in Alzheimer's disease and correlate with neuroimaging and cognitive biomarkers
Neurobiol Aging, 37, 12-18
DOI 10.1016/j.neurobiolaging.2015.09.010, PubMed 26476600

Mersov AM, Crane DE, Chappell MA, Black SE, MacIntosh BJ (2015)
Estimating the sample size required to detect an arterial spin labelling magnetic resonance imaging perfusion abnormality in voxel-wise group analyses
J Neurosci Methods, 245, 169-77
DOI 10.1016/j.jneumeth.2015.02.017, PubMed 25749568

Ou X, Crane DE, MacIntosh BJ, Young LT, Arnold P, Ameis S, Goldstein BI (2015)
CACNA1C rs1006737 genotype and bipolar disorder: Focus on intermediate phenotypes and cardiovascular comorbidity
Neurosci Biobehav Rev, 55, 198-210
DOI 10.1016/j.neubiorev.2015.04.022, PubMed 25976633

Robertson AD, Crane DE, Rajab AS, Swardfager W, Marzolini S, Shirzadi Z, Middleton LE, MacIntosh BJ (2015)
Exercise intensity modulates the change in cerebral blood flow following aerobic exercise in chronic stroke
Exp Brain Res, 233 (8), 2467-75
DOI 10.1007/s00221-015-4317-6, PubMed 26003127

Robertson AD, Messner MA, Shirzadi Z, Kleiner-Fisman G, Lee J, Hopyan J, Lang AE, Black SE, MacIntosh BJ, Masellis M (2015)
Orthostatic hypotension, cerebral hypoperfusion, and visuospatial deficits in Lewy body disorders
Parkinsonism Relat Disord, 22, 80-6
DOI 10.1016/j.parkreldis.2015.11.019, PubMed 26639982

Rohrer JD, Nicholas JM, Cash DM, van Swieten J, Dopper E, Jiskoot L, van Minkelen R, Rombouts SA, Cardoso MJ, Clegg S, Espak M, Mead S, Thomas DL, De Vita E, Masellis M, Black SE, Freedman M, Keren R, MacIntosh BJ, Rogaeva E, Tang-Wai D, Tartaglia MC, Laforce R, Tagliavini F, Tiraboschi P et al. (2015)
Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis
Lancet Neurol, 14 (3), 253-62
DOI 10.1016/S1474-4422(14)70324-2, PubMed 25662776

Shirzadi Z, Crane DE, Robertson AD, Maralani PJ, Aviv RI, Chappell MA, Goldstein BI, Black SE, MacIntosh BJ (2015)
Automated removal of spurious intermediate cerebral blood flow volumes improves image quality among older patients: A clinical arterial spin labeling investigation
J Magn Reson Imaging, 42 (5), 1377-85
DOI 10.1002/jmri.24918, PubMed 25873287

Subramaniapillai M, Goldstein BI, MacIntosh BJ, Korczak DJ, Ou X, Scavone A, Arbour-Nicitopoulos K, Faulkner G (2015)
Characterizing exercise-induced feelings after one bout of exercise among adolescents with and without bipolar disorder
J Affect Disord, 190, 467-473
DOI 10.1016/j.jad.2015.10.018, PubMed 26551406

Tchistiakova E, Crane DE, Mikulis DJ, Anderson ND, Greenwood CE, Black SE, MacIntosh BJ (2015)
Vascular risk factor burden correlates with cerebrovascular reactivity but not resting state coactivation in the default mode network
J Magn Reson Imaging, 42 (5), 1369-76
DOI 10.1002/jmri.24917, PubMed 25884110

Publications 2014

Alsop DC, Detre JA, Golay X, Günther M, Hendrikse J, Hernandez-Garcia L, Lu H, MacIntosh BJ, Parkes LM, Smits M, van Osch MJ, Wang DJ, Wong EC, Zaharchuk G (2014)
Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia
Magn Reson Med, 73 (1), 102-16
DOI 10.1002/mrm.25197, PubMed 24715426

MacIntosh BJ, Crane DE, Sage MD, Rajab AS, Donahue MJ, McIlroy WE, Middleton LE (2014)
Impact of a single bout of aerobic exercise on regional brain perfusion and activation responses in healthy young adults
PLoS One, 9 (1), e85163
DOI 10.1371/journal.pone.0085163, PubMed 24416356

MacIntosh BJ, Swardfager W, Crane DE, Ranepura N, Saleem M, Oh PI, Stefanovic B, Herrmann N, Lanctôt KL (2014)
Cardiopulmonary fitness correlates with regional cerebral grey matter perfusion and density in men with coronary artery disease
PLoS One, 9 (3), e91251
DOI 10.1371/journal.pone.0091251, PubMed 24622163

Mehndiratta A, Calamante F, MacIntosh BJ, Crane DE, Payne SJ, Chappell MA (2014)
Modeling and correction of bolus dispersion effects in dynamic susceptibility contrast MRI
Magn Reson Med, 72 (6), 1762-74
DOI 10.1002/mrm.25077, PubMed 24453108

Meusel LA, Kansal N, Tchistiakova E, Yuen W, MacIntosh BJ, Greenwood CE, Anderson ND (2014)
A systematic review of type 2 diabetes mellitus and hypertension in imaging studies of cognitive aging: time to establish new norms
Front Aging Neurosci, 6, 148
DOI 10.3389/fnagi.2014.00148, PubMed 25071557

Misch MR, Mitchell S, Francis PL, Sherborn K, Meradje K, McNeely AA, Honjo K, Zhao J, Scott CJ, Caldwell CB, Ehrlich L, Shammi P, MacIntosh BJ, Bilbao JM, Lang AE, Black SE, Masellis M (2014)
Differentiating between visual hallucination-free dementia with Lewy bodies and corticobasal syndrome on the basis of neuropsychology and perfusion single-photon emission computed tomography
Alzheimers Res Ther, 6 (9), 71
DOI 10.1186/s13195-014-0071-4, PubMed 25484929

Pavisian B, MacIntosh BJ, Szilagyi G, Staines RW, O'Connor P, Feinstein A (2014)
Effects of cannabis on cognition in patients with MS: a psychometric and MRI study
Neurology, 82 (21), 1879-87
DOI 10.1212/WNL.0000000000000446, PubMed 24789863

Rajab AS, Crane DE, Middleton LE, Robertson AD, Hampson M, MacIntosh BJ (2014)
A single session of exercise increases connectivity in sensorimotor-related brain networks: a resting-state fMRI study in young healthy adults
Front Hum Neurosci, 8, 625
DOI 10.3389/fnhum.2014.00625, PubMed 25177284

Tchistiakova E, Anderson ND, Greenwood CE, MacIntosh BJ (2014)
Combined effects of type 2 diabetes and hypertension associated with cortical thinning and impaired cerebrovascular reactivity relative to hypertension alone in older adults
Neuroimage Clin, 5, 36-41
DOI 10.1016/j.nicl.2014.05.020, PubMed 24967157

Publications 2013

Macintosh BJ, Graham SJ (2013)
Magnetic resonance imaging to visualize stroke and characterize stroke recovery: a review
Front Neurol, 4, 60
DOI 10.3389/fneur.2013.00060, PubMed 23750149

Makedonov I, Black SE, Macintosh BJ (2013)
BOLD fMRI in the white matter as a marker of aging and small vessel disease
PLoS One, 8 (7), e67652
DOI 10.1371/journal.pone.0067652, PubMed 23844047

Mehndiratta A, Calamante F, MacIntosh BJ, Crane DE, Payne SJ, Chappell MA (2013)
Modeling the residue function in DSC-MRI simulations: analytical approximation to in vivo data
Magn Reson Med, 72 (5), 1486-91
DOI 10.1002/mrm.25056, PubMed 24443102

Publications 2012

Blicher JU, Stagg CJ, O'Shea J, Østergaard L, MacIntosh BJ, Johansen-Berg H, Jezzard P, Donahue MJ (2012)
Visualization of altered neurovascular coupling in chronic stroke patients using multimodal functional MRI
J Cereb Blood Flow Metab, 32 (11), 2044-54
DOI 10.1038/jcbfm.2012.105, PubMed 22828998

Chappell MA, Woolrich MW, Kazan S, Jezzard P, Payne SJ, MacIntosh BJ (2012)
Modeling dispersion in arterial spin labeling: validation using dynamic angiographic measurements
Magn Reson Med, 69 (2), 563-70
DOI 10.1002/mrm.24260, PubMed 22489046

Crane DE, Donahue MJ, Chappell MA, Sideso E, Handa A, Kennedy J, Jezzard P, MacIntosh BJ (2012)
Evaluating quantitative approaches to dynamic susceptibility contrast MRI among carotid endarterectomy patients
J Magn Reson Imaging, 37 (4), 936-43
DOI 10.1002/jmri.23882, PubMed 23097408

Lindsay AC, Biasiolli L, Lee JM, Kylintireas I, MacIntosh BJ, Watt H, Jezzard P, Robson MD, Neubauer S, Handa A, Kennedy J, Choudhury RP (2012)
Plaque features associated with increased cerebral infarction after minor stroke and TIA: a prospective, case-control, 3-T carotid artery MR imaging study
JACC Cardiovasc Imaging, 5 (4), 388-96
DOI 10.1016/j.jcmg.2011.10.007, PubMed 22498328

Mehndiratta A, MacIntosh BJ, Crane DE, Payne SJ, Chappell MA (2012)
A control point interpolation method for the non-parametric quantification of cerebral haemodynamics from dynamic susceptibility contrast MRI
Neuroimage, 64, 560-70
DOI 10.1016/j.neuroimage.2012.08.083, PubMed 22975158

Middleton LE, Corbett D, Brooks D, Sage MD, Macintosh BJ, McIlroy WE, Black SE (2012)
Physical activity in the prevention of ischemic stroke and improvement of outcomes: a narrative review
Neurosci Biobehav Rev, 37 (2), 133-7
DOI 10.1016/j.neubiorev.2012.11.011, PubMed 23201860

Publications 2011

MacIntosh BJ, Sideso E, Donahue MJ, Chappell MA, Günther M, Handa A, Kennedy J, Jezzard P (2011)
Intracranial hemodynamics is altered by carotid artery disease and after endarterectomy: a dynamic magnetic resonance angiography study
Stroke, 42 (4), 979-84
DOI 10.1161/STROKEAHA.110.590786, PubMed 21350206

Publications 2010

Chappell MA, MacIntosh BJ, Donahue MJ, Günther M, Jezzard P, Woolrich MW (2010)
Separation of macrovascular signal in multi-inversion time arterial spin labelling MRI
Magn Reson Med, 63 (5), 1357-65
DOI 10.1002/mrm.22320, PubMed 20432306

Donahue MJ, Sideso E, MacIntosh BJ, Kennedy J, Handa A, Jezzard P (2010)
Absolute arterial cerebral blood volume quantification using inflow vascular-space-occupancy with dynamic subtraction magnetic resonance imaging
J Cereb Blood Flow Metab, 30 (7), 1329-42
DOI 10.1038/jcbfm.2010.16, PubMed 20145656

MacIntosh BJ, Filippini N, Chappell MA, Woolrich MW, Mackay CE, Jezzard P (2010)
Assessment of arterial arrival times derived from multiple inversion time pulsed arterial spin labeling MRI
Magn Reson Med, 63 (3), 641-7
DOI 10.1002/mrm.22256, PubMed 20146233

Mayhew SD, Macintosh BJ, Dirckx SG, Iannetti GD, Wise RG (2010)
Coupling of simultaneously acquired electrophysiological and haemodynamic responses during visual stimulation
Magn Reson Imaging, 28 (8), 1066-77
DOI 10.1016/j.mri.2010.03.027, PubMed 20399582

Sörös P, Macintosh BJ, Tam F, Graham SJ (2010)
fMRI-Compatible Registration of Jaw Movements Using a Fiber-Optic Bend Sensor
Front Hum Neurosci, 4, 24
DOI 10.3389/fnhum.2010.00024, PubMed 20463865

Publications 2009

Donahue MJ, Blicher JU, Østergaard L, Feinberg DA, MacIntosh BJ, Miller KL, Günther M, Jezzard P (2009)
Cerebral blood flow, blood volume, and oxygen metabolism dynamics in human visual and motor cortex as measured by whole-brain multi-modal magnetic resonance imaging
J Cereb Blood Flow Metab, 29 (11), 1856-66
DOI 10.1038/jcbfm.2009.107, PubMed 19654592

Filippini N, MacIntosh BJ, Hough MG, Goodwin GM, Frisoni GB, Smith SM, Matthews PM, Beckmann CF, Mackay CE (2009)
Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele
Proc Natl Acad Sci U S A, 106 (17), 7209-14
DOI 10.1073/pnas.0811879106, PubMed 19357304

Pattinson KT, Governo RJ, MacIntosh BJ, Russell EC, Corfield DR, Tracey I, Wise RG (2009)
Opioids depress cortical centers responsible for the volitional control of respiration
J Neurosci, 29 (25), 8177-86
DOI 10.1523/JNEUROSCI.1375-09.2009, PubMed 19553457

Publications 2008

MacIntosh BJ, McIlroy WE, Mraz R, Staines WR, Black SE, Graham SJ (2008)
Electrodermal recording and fMRI to inform sensorimotor recovery in stroke patients
Neurorehabil Neural Repair, 22 (6), 728-36
DOI 10.1177/1545968308316386, PubMed 18784267

MacIntosh BJ, Pattinson KT, Gallichan D, Ahmad I, Miller KL, Feinberg DA, Wise RG, Jezzard P (2008)
Measuring the effects of remifentanil on cerebral blood flow and arterial arrival time using 3D GRASE MRI with pulsed arterial spin labelling
J Cereb Blood Flow Metab, 28 (8), 1514-22
DOI 10.1038/jcbfm.2008.46, PubMed 18506198

Pattinson KT, Rogers R, Mayhew SD, MacIntosh BJ, Lee MC, Wise RG (2008)
Remifentanil-induced cerebral blood flow effects in normal humans: dose and ApoE genotype
Anesth Analg, 106 (1), 347; author reply 347-8
DOI 10.1213/01.ane.0000297279.12358.29, PubMed 18165607

Publications 2007

MacIntosh BJ, Baker SN, Mraz R, Ives JR, Martel AL, McIlroy WE, Graham SJ (2007)
Improving functional magnetic resonance imaging motor studies through simultaneous electromyography recordings
Hum Brain Mapp, 28 (9), 835-45
DOI 10.1002/hbm.20308, PubMed 17133382

Macintosh BJ, Mraz R, McIlroy WE, Graham SJ (2007)
Brain activity during a motor learning task: an fMRI and skin conductance study
Hum Brain Mapp, 28 (12), 1359-67
DOI 10.1002/hbm.20351, PubMed 17318835

Publications 2004

MacIntosh BJ, Mraz R, Baker N, Tam F, Staines WR, Graham SJ (2004)
Optimizing the experimental design for ankle dorsiflexion fMRI
Neuroimage, 22 (4), 1619-27
DOI 10.1016/j.neuroimage.2004.03.035, PubMed 15275918

Martin RE, MacIntosh BJ, Smith RC, Barr AM, Stevens TK, Gati JS, Menon RS (2004)
Cerebral areas processing swallowing and tongue movement are overlapping but distinct: a functional magnetic resonance imaging study
J Neurophysiol, 92 (4), 2428-43
DOI 10.1152/jn.01144.2003, PubMed 15163677

Publications 2003

MacIntosh BJ, Klassen LM, Menon RS (2003)
Transient hemodynamics during a breath hold challenge in a two part functional imaging study with simultaneous near-infrared spectroscopy in adult humans
Neuroimage, 20 (2), 1246-52
DOI 10.1016/S1053-8119(03)00417-8, PubMed 14568493

Publications 2002

Klassen LM, MacIntosh BJ, Menon RS (2002)
Influence of hypoxia on wavelength dependence of differential pathlength and near-infrared quantification
Phys Med Biol, 47 (9), 1573-89
DOI 10.1088/0031-9155/47/9/311, PubMed 12043821

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