Gunn A. Hildrestrand
- Researcher; PhD
- +47 23 01 39 11
Mammalian group
Publications 2021
Impact of Oxidative DNA Damage and the Role of DNA Glycosylases in Neurological Dysfunction
Int J Mol Sci, 22 (23)
DOI 10.3390/ijms222312924, PubMed 34884729
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
Commun Biol, 4 (1), 1354
DOI 10.1038/s42003-021-02864-x, PubMed 34857879
Publications 2020
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
Cell Rep, 30 (12), 4165-4178.e7
DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476
Publications 2017
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice
Sci Rep, 7 (1), 4384
DOI 10.1038/s41598-017-04472-4, PubMed 28663564
Publications 2016
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Sci Rep, 6, 28337
DOI 10.1038/srep28337, PubMed 27328939
Publications 2015
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice
Cell Rep, 13 (12), 2671-8
DOI 10.1016/j.celrep.2015.12.001, PubMed 26711335
Publications 2013
Loss of Neil3, the major DNA glycosylase activity for removal of hydantoins in single stranded DNA, reduces cellular proliferation and sensitizes cells to genotoxic stress
Biochim Biophys Acta, 1833 (5), 1157-64
DOI 10.1016/j.bbamcr.2012.12.024, PubMed 23305905
Publications 2012
Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice
Hum Mol Genet, 21 (22), 4939-47
DOI 10.1093/hmg/dds337, PubMed 22914735
Hippocampal adult neurogenesis is maintained by Neil3-dependent repair of oxidative DNA lesions in neural progenitor cells
Cell Rep, 2 (3), 503-10
DOI 10.1016/j.celrep.2012.08.008, PubMed 22959434
Publications 2011
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia
Proc Natl Acad Sci U S A, 108 (46), 18802-7
DOI 10.1073/pnas.1106880108, PubMed 22065741
Publications 2009
Intracellular localization and expression patterns of DNAglycosylases and their activities in murine and human stem cells
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 783, 1 b. (flere pag.)
BIBSYS 092931499, ISBN 978-82-8072-792-3
Modulation of DNA glycosylase activities in mesenchymal stem cells
Exp Cell Res, 315 (15), 2558-67
DOI 10.1016/j.yexcr.2009.05.017, PubMed 19477173
Expression patterns of Neil3 during embryonic brain development and neoplasia
BMC Neurosci, 10, 45
DOI 10.1186/1471-2202-10-45, PubMed 19426544
Publications 2007
The capacity to remove 8-oxoG is enhanced in newborn neural stem/progenitor cells and decreases in juvenile mice and upon cell differentiation
DNA Repair (Amst), 6 (6), 723-32
DOI 10.1016/j.dnarep.2006.12.008, PubMed 17236821
Human NEIL1 localizes with the centrosomes and condensed chromosomes during mitosis
DNA Repair (Amst), 6 (10), 1425-33
DOI 10.1016/j.dnarep.2007.04.008, PubMed 17556049
Publications 2005
Dynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harbouring the hOGG1-Cys326 polymorphic variant
Nucleic Acids Res, 33 (6), 1813-24
DOI 10.1093/nar/gki325, PubMed 15800211
Publications 2000
Atlantic salmon (Salmo salar) estrogen receptor β: cloning and characterization of a partial cDNA
[G.A. Hildrestrand], Bergen, VI, 92 bl.
BIBSYS 001250345