Geir Andre Ringstad
- Consultant Neuroradiologist; MD, PhD
- +47 23 07 15 73
Publications 2024
Unravelling pituitary tumours in medically treated patients with acromegaly: the impact of systematic MRI reassessment
Acta Radiol, 65 (7), 753-758
DOI 10.1177/02841851241246107, PubMed 38659302
Glymphatic-stagnated edema induced by traumatic brain injury
Trends Pharmacol Sci, 45 (5), 388-390
DOI 10.1016/j.tips.2024.01.005, PubMed 38290921
Functional analysis of the human perivascular subarachnoid space
Nat Commun, 15 (1), 2001
DOI 10.1038/s41467-024-46329-1, PubMed 38443374
Significant individual variation in cardiac-cycle-linked cerebrospinal fluid production following subarachnoid hemorrhage
Fluids Barriers CNS, 21 (1), 85
DOI 10.1186/s12987-024-00587-9, PubMed 39438961
Long-term intrathecal infusion of low-dose morphine effectively relieves symptoms of severe restless legs syndrome/Willis-Ekbom disease without inducing opioid tolerance
Pain (in press)
DOI 10.1097/j.pain.0000000000003311, PubMed 39106456
Empowering early career vascular neurosurgeons in the endovascular Era: Managing intraoperative aneurysm rupture through a systematic algorithmic approach
J Clin Neurosci, 120, 229-231
DOI 10.1016/j.jocn.2024.01.006, PubMed 38306902
Glymphatic imaging: a critical look at the DTI-ALPS index
Neuroradiology, 66 (2), 157-160
DOI 10.1007/s00234-023-03270-2, PubMed 38197950
Glymphatic-lymphatic coupling: assessment of the evidence from magnetic resonance imaging of humans
Cell Mol Life Sci, 81 (1), 131
DOI 10.1007/s00018-024-05141-2, PubMed 38472405
Human brain clearance imaging: Pathways taken by magnetic resonance imaging contrast agents after administration in cerebrospinal fluid and blood
NMR Biomed, 37 (9), e5159
DOI 10.1002/nbm.5159, PubMed 38634301
Publications 2023
Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 "ISMRM Imaging Neurofluids Study group" Workshop in Rome
J Magn Reson Imaging, 59 (2), 431-449
DOI 10.1002/jmri.28759, PubMed 37141288
Plasma neurodegeneration biomarker concentrations associate with glymphatic and meningeal lymphatic measures in neurological disorders
Nat Commun, 14 (1), 2084
DOI 10.1038/s41467-023-37685-5, PubMed 37045847
Mechanisms behind changes of neurodegeneration biomarkers in plasma induced by sleep deprivation
Brain Commun, 5 (6), fcad343
DOI 10.1093/braincomms/fcad343, PubMed 38130841
Physiological alterations of pineal recess crowding in symptomatic non-hydrocephalic pineal cysts
Brain Commun, 5 (2), fcad078
DOI 10.1093/braincomms/fcad078, PubMed 37501910
Low versus High Intracranial Compliance in Adult Patients with Chiari Malformation Type 1-Comparison of Long-Term Outcome After Tailored Treatment
World Neurosurg, 173, e699-e707
DOI 10.1016/j.wneu.2023.02.134, PubMed 36889634
Spinal artery infarction
Tidsskr Nor Laegeforen, 143 (4)
DOI 10.4045/tidsskr.22.0355, PubMed 36919304
TGFBR3L is associated with gonadotropin production in non-functioning gonadotroph pituitary neuroendocrine tumours
Pituitary, 26 (2), 227-236
DOI 10.1007/s11102-023-01310-x, PubMed 36952069
Author Correction: In vivo assessment of cerebrospinal fluid efflux to nasal mucosa in humans
Sci Rep, 13 (1), 16607
DOI 10.1038/s41598-023-43372-8, PubMed 37789145
In vivo distribution of cerebrospinal fluid tracer in human upper spinal cord and brain stem
JCI Insight, 8 (23)
DOI 10.1172/jci.insight.173276, PubMed 38063195
Human parasagittal dura is a potential neuroimmune interface
Commun Biol, 6 (1), 260
DOI 10.1038/s42003-023-04634-3, PubMed 36906686
The pitfalls of interpreting hyperintense FLAIR signal as lymph outside the human brain
Nat Commun, 14 (1), 4913
DOI 10.1038/s41467-023-40508-2, PubMed 37587121
Prospective T1 mapping to assess gadolinium retention in brain after intrathecal gadobutrol
Neuroradiology, 65 (9), 1321-1331
DOI 10.1007/s00234-023-03198-7, PubMed 37479768
Prospective Safety Study of Intrathecal Gadobutrol in Different Doses
AJNR Am J Neuroradiol, 44 (5), 511-516
DOI 10.3174/ajnr.A7841, PubMed 37024308
Human brain solute transport quantified by glymphatic MRI-informed biophysics during sleep and sleep deprivation
Fluids Barriers CNS, 20 (1), 62
DOI 10.1186/s12987-023-00459-8, PubMed 37596635
Prevalence of pineal cysts in healthy individuals: Emphasis on size, morphology and pineal recess crowding
J Neurol Sci, 453, 120801
DOI 10.1016/j.jns.2023.120801, PubMed 37741123
Publications 2022
Intrathecal Contrast-Enhanced Magnetic Resonance Imaging of Cerebrospinal Fluid Dynamics and Glymphatic Enhancement in Idiopathic Normal Pressure Hydrocephalus
Front Neurol, 13, 857328
DOI 10.3389/fneur.2022.857328, PubMed 35463139
Altered glymphatic enhancement of cerebrospinal fluid tracer in individuals with chronic poor sleep quality
J Cereb Blood Flow Metab, 42 (9), 1676-1692
DOI 10.1177/0271678X221090747, PubMed 35350917
CSF circulation and dispersion yield rapid clearance from intracranial compartments
Front Bioeng Biotechnol, 10, 932469
DOI 10.3389/fbioe.2022.932469, PubMed 36172015
Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders
Fluids Barriers CNS, 19 (1), 55
DOI 10.1186/s12987-022-00352-w, PubMed 35778719
Molecular trans-dural efflux to skull bone marrow in humans with CSF disorders
Brain, 145 (4), 1464-1472
DOI 10.1093/brain/awab388, PubMed 34849609
Investigating molecular transport in the human brain from MRI with physics-informed neural networks
Sci Rep, 12 (1), 15475
DOI 10.1038/s41598-022-19157-w, PubMed 36104360
Publications 2021
Cognition in adult patients with newly diagnosed non-lesional temporal lobe epilepsy
Epilepsy Behav, 116, 107771
DOI 10.1016/j.yebeh.2021.107771, PubMed 33545650
Clinical application of intrathecal gadobutrol for assessment of cerebrospinal fluid tracer clearance to blood
JCI Insight, 6 (9)
DOI 10.1172/jci.insight.147063, PubMed 33822769
Impaired glymphatic function in idiopathic intracranial hypertension
Brain Commun, 3 (2), fcab043
DOI 10.1093/braincomms/fcab043, PubMed 34235434
Cerebrospinal fluid egress to human parasagittal dura and the impact of sleep deprivation
Brain Res, 1772, 147669
DOI 10.1016/j.brainres.2021.147669, PubMed 34587499
Direction and magnitude of cerebrospinal fluid flow vary substantially across central nervous system diseases
Fluids Barriers CNS, 18 (1), 16
DOI 10.1186/s12987-021-00251-6, PubMed 33794929
Sleep deprivation impairs molecular clearance from the human brain
Brain, 144 (3), 863-874
DOI 10.1093/brain/awaa443, PubMed 33829232
Safety of Intrathecal Gadolinium-based Contrast Agents and Benefit versus Risk
Radiology, 299 (1), E223-E224
DOI 10.1148/radiol.2021203351, PubMed 33591893
Publications 2020
<b>Magnetic resonance imaging biomarkers of cerebrospinal fluid tracer dynamics</b> <b>in idiopathic normal pressure hydrocephalus</b>
Brain Commun, 2 (2), fcaa187
DOI 10.1093/braincomms/fcaa187, PubMed 33381757
Off-label intrathecal use of gadobutrol: safety study and comparison of administration protocols
Neuroradiology, 63 (1), 51-61
DOI 10.1007/s00234-020-02519-4, PubMed 32803338
In Vivo Evidence for Impaired Glymphatic Function in the Visual Pathway of Patients With Normal Pressure Hydrocephalus
Invest Ophthalmol Vis Sci, 61 (13), 24
DOI 10.1167/iovs.61.13.24, PubMed 33201186
FSH Levels Are Related to E-cadherin Expression and Subcellular Location in Nonfunctioning Pituitary Tumors
J Clin Endocrinol Metab, 105 (8), 2587-94
DOI 10.1210/clinem/dgaa281, PubMed 32421791
Surgery for Brainstem Cavernous Malformations: Association between Preoperative Grade and Postoperative Quality of Life
Oper Neurosurg (Hagerstown), 18 (6), 590-598
DOI 10.1093/ons/opz337, PubMed 31768544
In vivo assessment of cerebrospinal fluid efflux to nasal mucosa in humans
Sci Rep, 10 (1), 14974
DOI 10.1038/s41598-020-72031-5, PubMed 32917953
Glymphatic MRI
Tidsskr Nor Laegeforen, 140 (1)
DOI 10.4045/tidsskr.19.0651, PubMed 31948208
Cerebrospinal fluid tracer efflux to parasagittal dura in humans
Nat Commun, 11 (1), 354
DOI 10.1038/s41467-019-14195-x, PubMed 31953399
Glymphatic MRI
Tidsskr. Nor. Laegeforen., 140 (1), 69
Apparent diffusion coefficient estimates based on 24 hours tracer movement support glymphatic transport in human cerebral cortex
Sci Rep, 10 (1), 9176
DOI 10.1038/s41598-020-66042-5, PubMed 32514105
Publications 2019
Intrathecal Use of Gadobutrol for Glymphatic MR Imaging: Prospective Safety Study of 100 Patients
AJNR Am J Neuroradiol, 40 (8), 1257-1264
DOI 10.3174/ajnr.A6136, PubMed 31320462
In Vivo Imaging of Molecular Clearance From Human Entorhinal Cortex: A Possible Method for Preclinical Testing of Dementia
Gerontol Geriatr Med, 5, 2333721419889739
DOI 10.1177/2333721419889739, PubMed 31819895
Delayed clearance of cerebrospinal fluid tracer from choroid plexus in idiopathic normal pressure hydrocephalus
J Cereb Blood Flow Metab, 40 (9), 1849-1858
DOI 10.1177/0271678X19874790, PubMed 31495299
[Chiari malformation type 1 – diagnosis and treatment]
Tidsskr Nor Laegeforen, 139 (10)
DOI 10.4045/tidsskr.18.0455, PubMed 31238671
Chiari malformation type 1- diagnostics and treatment
Tidsskr. Nor. Laegeforen., 139 (10), 931-935
The Human Visual Pathway Communicates Directly With the Subarachnoid Space
Invest Ophthalmol Vis Sci, 60 (7), 2773-2780
DOI 10.1167/iovs.19-26997, PubMed 31247084
Respiratory influence on cerebrospinal fluid flow - a computational study based on long-term intracranial pressure measurements
Sci Rep, 9 (1), 9732
DOI 10.1038/s41598-019-46055-5, PubMed 31278278
Publications 2018
Aggressive melanoma in an infant with congenital melanocytic nevus syndrome and multiple, NRAS and BRAF mutation-negative nodules
Pediatr Dermatol, 35 (5), e281-e285
DOI 10.1111/pde.13595, PubMed 29999207
Delayed clearance of cerebrospinal fluid tracer from entorhinal cortex in idiopathic normal pressure hydrocephalus: A glymphatic magnetic resonance imaging study
J Cereb Blood Flow Metab, 39 (7), 1355-1368
DOI 10.1177/0271678X18760974, PubMed 29485341
"Bucket" cerebrospinal fluid bulk flow: when the terrain disagrees with the map
Acta Neurochir (Wien), 161 (2), 259-261
DOI 10.1007/s00701-018-3775-6, PubMed 30560378
Magnetic resonance imaging provides evidence of glymphatic drainage from human brain to cervical lymph nodes
Sci Rep, 8 (1), 7194
DOI 10.1038/s41598-018-25666-4, PubMed 29740121
Cerebrospinal fluid volumetric net flow rate and direction in idiopathic normal pressure hydrocephalus
Neuroimage Clin, 20, 731-741
DOI 10.1016/j.nicl.2018.09.006, PubMed 30238917
Magnitude and direction of aqueductal cerebrospinal fluid flow: large variations in patients with intracranial aneurysms with or without a previous subarachnoid hemorrhage
Acta Neurochir (Wien), 161 (2), 247-256
DOI 10.1007/s00701-018-3730-6, PubMed 30443816
Comparison of phase-contrast MR and flow simulations for the study of CSF dynamics in the cervical spine
Neuroradiol J, 31 (3), 292-298
DOI 10.1177/1971400918759812, PubMed 29464985
Brain-wide glymphatic enhancement and clearance in humans assessed with MRI
JCI Insight, 3 (13)
DOI 10.1172/jci.insight.121537, PubMed 29997300
Are volume measurements of non-functioning pituitary adenomas reliable?
Endocrine, 63 (1), 171-176
DOI 10.1007/s12020-018-1752-8, PubMed 30259294
Publications 2017
The Evans' Index revisited: New cut-off levels for use in radiological assessment of ventricular enlargement in the elderly
Eur J Radiol, 95, 28-32
DOI 10.1016/j.ejrad.2017.07.013, PubMed 28987681
Anatomical features of the cervical spinal canal in Chiari I deformity with presyrinx: A case-control study
Neuroradiol J, 30 (5), 405-409
DOI 10.1177/1971400917718842, PubMed 28691569
Direct numerical simulation of transitional hydrodynamics of the cerebrospinal fluid in Chiari I malformation: The role of cranio-vertebral junction
Int J Numer Method Biomed Eng, 33 (9)
DOI 10.1002/cnm.2853, PubMed 27863152
Non-invasive assessment of pulsatile intracranial pressure with phase-contrast magnetic resonance imaging
PLoS One, 12 (11), e0188896
DOI 10.1371/journal.pone.0188896, PubMed 29190788
Glymphatic MRI in idiopathic normal pressure hydrocephalus
Brain, 140 (10), 2691-2705
DOI 10.1093/brain/awx191, PubMed 28969373
Early postoperative growth in non-functioning pituitary adenomas; A tool to tailor safe follow-up
Endocrine, 57 (1), 35-45
DOI 10.1007/s12020-017-1314-5, PubMed 28516382
Publications 2016
Magnetic resonance imaging biomarkers indicate a central venous hypertension syndrome in patients with symptomatic pineal cysts
J Neurol Sci, 363, 207-16
DOI 10.1016/j.jns.2016.02.038, PubMed 27000252
Increased pulsatile intracranial pressure in patients with symptomatic pineal cysts and magnetic resonance imaging biomarkers indicative of central venous hypertension
J Neurol Sci, 367, 247-55
DOI 10.1016/j.jns.2016.06.028, PubMed 27423599
Results of surgery in symptomatic non-hydrocephalic pineal cysts: role of magnetic resonance imaging biomarkers indicative of central venous hypertension
Acta Neurochir (Wien), 159 (2), 349-361
DOI 10.1007/s00701-016-3029-4, PubMed 27878615
[Idiopathic intracranial hypertension as a cause of headache]
Tidsskr Nor Laegeforen, 136 (22), 1895-1898
DOI 10.4045/tidsskr.16.0222, PubMed 27929555
The association between the pulse pressure gradient at the cranio-cervical junction derived from phase-contrast magnetic resonance imaging and invasively measured pulsatile intracranial pressure in symptomatic patients with Chiari malformation type 1
Acta Neurochir (Wien), 158 (12), 2295-2304
DOI 10.1007/s00701-016-2979-x, PubMed 27743249
Radiological imaging in acute ischaemic stroke
Eur J Neurol, 23 Suppl 1, 8-17
DOI 10.1111/ene.12849, PubMed 26563093
Computational Investigation of Cerebrospinal Fluid Dynamics in the Posterior Cranial Fossa and Cervical Subarachnoid Space in Patients with Chiari I Malformation
PLoS One, 11 (10), e0162938
DOI 10.1371/journal.pone.0162938, PubMed 27727298
Publications 2015
MRI with intrathecal MRI gadolinium contrast medium administration: a possible method to assess glymphatic function in human brain
Acta Radiol Open, 4 (11), 2058460115609635
DOI 10.1177/2058460115609635, PubMed 26634147
Quantitative analyses of T2-weighted MRI as a potential marker for response to somatostatin analogs in newly diagnosed acromegaly
Endocrine, 52 (2), 333-43
DOI 10.1007/s12020-015-0766-8, PubMed 26475495
MRI T2 characteristics in somatotroph adenomas following somatostatin analog treatment in acromegaly
Endocrine, 53 (1), 327-30
DOI 10.1007/s12020-015-0816-2, PubMed 26615593
Phase-contrast magnetic resonance imaging reveals net retrograde aqueductal flow in idiopathic normal pressure hydrocephalus
J Neurosurg, 124 (6), 1850-7
DOI 10.3171/2015.6.JNS15496, PubMed 26636385
Aqueductal Stroke Volume: Comparisons with Intracranial Pressure Scores in Idiopathic Normal Pressure Hydrocephalus
AJNR Am J Neuroradiol, 36 (9), 1623-30
DOI 10.3174/ajnr.A4340, PubMed 25977480
Reply: To PMID 25977480
AJNR Am J Neuroradiol, 36 (9), 1633-4
DOI 10.3174/ajnr.A4488, PubMed 26251437
Publications 2014
Severe macrophage activation syndrome and central nervous system involvement in juvenile dermatomyositis
Scand J Rheumatol, 43 (2), 171-3
DOI 10.3109/03009742.2013.863968, PubMed 24588361
[Woman with recurrent uveitis and neurological symptoms]
Tidsskr Nor Laegeforen, 134 (12-13), 1245-8
DOI 10.4045/tidsskr.13.0433, PubMed 24989204
Usefulness of the endoscope in microvascular decompression for trigeminal neuralgia and MRI-based prediction of the need for endoscopy
Acta Neurochir (Wien), 156 (10), 1901-9; discussion 1909
DOI 10.1007/s00701-014-2171-0, PubMed 25008460
Publications 2013
Attenuated RORC expression in the presence of EMT progression in somatotroph adenomas following treatment with somatostatin analogs is associated with poor clinical recovery
PLoS One, 8 (6), e66927
DOI 10.1371/journal.pone.0066927, PubMed 23825587
Epithelial splicing regulator protein 1 and alternative splicing in somatotroph adenomas
Endocrinology, 154 (9), 3331-43
DOI 10.1210/en.2013-1051, PubMed 23825128
Publications 2012
Intensity of pituitary adenoma on T2-weighted magnetic resonance imaging predicts the response to octreotide treatment in newly diagnosed acromegaly
Clin Endocrinol (Oxf), 77 (1), 72-8
DOI 10.1111/j.1365-2265.2011.04286.x, PubMed 22066905
An unusual case of the syndrome of cervical rib with subclavian artery thrombosis and cerebellar and cerebral infarctions
BMC Neurol, 12, 48
DOI 10.1186/1471-2377-12-48, PubMed 22741548
Publications 2011
[A 55-year old man with recurrent brain infarction]
Tidsskr Nor Laegeforen, 131 (11), 1089-91
DOI 10.4045/tidsskr.10.0162, PubMed 21681238
Assessment of pituitary adenoma volumetric change using longitudinal MR image registration
Neuroradiology, 54 (5), 435-43
DOI 10.1007/s00234-011-0894-7, PubMed 21647587
Publications 2010
An autostereoscopic 3D display can improve visualization of 3D models from intracranial MR angiography
Int J Comput Assist Radiol Surg, 5 (5), 549-54
DOI 10.1007/s11548-010-0509-5, PubMed 20652646
Publications 2007
Periodic abducens nerve palsy in adults caused by neurovascular compression
J Neurol Neurosurg Psychiatry, 79 (1), 100-2
DOI 10.1136/jnnp.2007.124321, PubMed 17717022
Publications 2006
[CT colonography: a new method for detecting colorectal cancer and polyps]
Tidsskr Nor Laegeforen, 126 (11), 1470-3
PubMed 16732340
Publications 2003
Bonitetsutvikling og avvik mellom plan og kontroll
[Forfatterne], Ås, 47 bl.
BIBSYS 040859177