Publications

Publications 2025

  1. Dyhr E, Sæbo̷ IP, Riisnæs IMM, Bjo̷rås M, Helgesen E, Booth JA, Franzyk H (2025)
    Rational Design of Antimicrobial Peptides Based on Bacterial Type‑I Toxins AapA1, IbsC, and Fst1
    ACS Omega, 10 (24), 25790-25800
    DOI 10.1021/acsomega.5c01863, PubMed 40584331
  2. Lobie TA, Krog CS, Skarstad K, Bjørås M, Booth JA (2025)
    Escherichia coli type I toxin TisB exclusively controls proton depolarization following antibiotic induced DNA damage
    Sci Rep, 15 (1), 12774
    DOI 10.1038/s41598-025-96136-x, PubMed 40229382
  3. Sæbø IP, Dyhr E, Riisnæs IMM, Franzyk H, Bjørås M, Booth JA, Helgesen E (2025)
    Rational design of synthetic antimicrobial peptides based on the Escherichia coli ShoB toxin
    Sci Rep, 15 (1), 14354
    DOI 10.1038/s41598-025-98330-3, PubMed 40274891
  4. Vikedal K, Ræder SB, Riisnæs IMM, Bjørås M, Booth JA, Skarstad K, Helgesen E (2025)
    RecN and RecA orchestrate an ordered DNA supercompaction response following ciprofloxacin-induced DNA damage in Escherichia coli
    Nucleic Acids Res, 53 (10)
    DOI 10.1093/nar/gkaf437, PubMed 40433982

Publications 2023

  1. Sæbø IP, Bjørås M, Franzyk H, Helgesen E, Booth JA (2023)
    Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity
    Int J Mol Sci, 24 (3)
    DOI 10.3390/ijms24032914, PubMed 36769243
  2. Thorfinnsdottir LB, Bø GH, Booth JA, Bruheim P (2023)
    Survival of Escherichia coli after high-antibiotic stress is dependent on both the pregrown physiological state and incubation conditions
    Front Microbiol, 14, 1149978
    DOI 10.3389/fmicb.2023.1149978, PubMed 36970700

Publications 2021

  1. Helgesen E, Sætre F, Skarstad K (2021)
    Topoisomerase IV tracks behind the replication fork and the SeqA complex during DNA replication in Escherichia coli
    Sci Rep, 11 (1), 474
    DOI 10.1038/s41598-020-80043-4, PubMed 33436807
  2. Lobie TA, Roba AA, Booth JA, Kristiansen KI, Aseffa A, Skarstad K, Bjørås M (2021)
    Antimicrobial resistance: A challenge awaiting the post-COVID-19 era
    Int J Infect Dis, 111, 322-325
    DOI 10.1016/j.ijid.2021.09.003, PubMed 34508864

Publications 2020

  1. Booth JA, Špírek M, Lobie TA, Skarstad K, Krejci L, Bjørås M (2020)
    Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability
    Sci Rep, 10 (1), 19422
    DOI 10.1038/s41598-020-76426-2, PubMed 33173044
  2. Nedal A, Ræder SB, Dalhus B, Helgesen E, Forstrøm RJ, Lindland K, Sumabe BK, Martinsen JH, Kragelund BB, Skarstad K, Bjørås M, Otterlei M (2020)
    Peptides containing the PCNA interacting motif APIM bind to the β-clamp and inhibit bacterial growth and mutagenesis
    Nucleic Acids Res, 48 (10), 5540-5554
    DOI 10.1093/nar/gkaa278, PubMed 32347931

Publications 2017

  1. Flåtten I, Helgesen E, Pedersen IB, Waldminghaus T, Rothe C, Taipale R, Johnsen L, Skarstad K (2017)
    Phenotypes of dnaXE145A Mutant Cells Indicate that the Escherichia coli Clamp Loader Has a Role in the Restart of Stalled Replication Forks
    J Bacteriol, 199 (24)
    DOI 10.1128/JB.00412-17, PubMed 28947673
  2. Pedersen IB, Helgesen E, Flåtten I, Fossum-Raunehaug S, Skarstad K (2017)
    SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms
    Nucleic Acids Res, 45 (11), 6471-6485
    DOI 10.1093/nar/gkx263, PubMed 28407100

Publications 2016

  1. Helgesen E, Fossum-Raunehaug S, Skarstad K (2016)
    Lack of the H-NS Protein Results in Extended and Aberrantly Positioned DNA during Chromosome Replication and Segregation in Escherichia coli
    J Bacteriol, 198 (8), 1305-16
    DOI 10.1128/JB.00919-15, PubMed 26858102
  2. Kristiansen KI, Weel-Sneve R, Booth JA, Bjørås M (2016)
    Mutually exclusive RNA secondary structures regulate translation initiation of DinQ in Escherichia coli
    RNA, 22 (11), 1739-1749
    DOI 10.1261/rna.058461.116, PubMed 27651528

Publications 2015

  1. Helgesen E, Fossum-Raunehaug S, Sætre F, Schink KO, Skarstad K (2015)
    Dynamic Escherichia coli SeqA complexes organize the newly replicated DNA at a considerable distance from the replisome
    Nucleic Acids Res, 43 (5), 2730-43
    DOI 10.1093/nar/gkv146, PubMed 25722374

Publications 2014

  1. Booth JA, Suganthan R, Gaustad P, Bjørås M (2014)
    Development of DinQ from Escherichia coli as an anti-cell-envelope antibiotic
    Int J Antimicrob Agents, 45 (2), 196-7
    DOI 10.1016/j.ijantimicag.2014.10.005, PubMed 25465525
  2. Fossum-Raunehaug S, Helgesen E, Stokke C, Skarstad K (2014)
    Escherichia coli SeqA structures relocalize abruptly upon termination of origin sequestration during multifork DNA replication
    PLoS One, 9 (10), e110575
    DOI 10.1371/journal.pone.0110575, PubMed 25333813

Publications 2013

  1. Booth JA, Thomassen GO, Rowe AD, Weel-Sneve R, Lagesen K, Kristiansen KI, Bjørås M, Rognes T, Lindvall JM (2013)
    Tiling array study of MNNG treated Escherichia coli reveals a widespread transcriptional response
    Sci Rep, 3, 3053
    DOI 10.1038/srep03053, PubMed 24157950
  2. Weel-Sneve R, Kristiansen KI, Odsbu I, Dalhus B, Booth J, Rognes T, Skarstad K, Bjørås M (2013)
    Single transmembrane peptide DinQ modulates membrane-dependent activities
    PLoS Genet, 9 (2), e1003260
    DOI 10.1371/journal.pgen.1003260, PubMed 23408903

Publications 2012

  1. Hak S, Helgesen E, Hektoen HH, Huuse EM, Jarzyna PA, Mulder WJ, Haraldseth O, Davies Cde L (2012)
    The effect of nanoparticle polyethylene glycol surface density on ligand-directed tumor targeting studied in vivo by dual modality imaging
    ACS Nano, 6 (6), 5648-58
    DOI 10.1021/nn301630n, PubMed 22671719

Publications 2010

  1. Thomassen GO, Weel-Sneve R, Rowe AD, Booth JA, Lindvall JM, Lagesen K, Kristiansen KI, Bjørås M, Rognes T (2010)
    Tiling array analysis of UV treated Escherichia coli predicts novel differentially expressed small peptides
    PLoS One, 5 (12), e15356
    DOI 10.1371/journal.pone.0015356, PubMed 21203457

Publications 2008

  1. Olsen PA, Solhaug A, Booth JA, Gelazauskaite M, Krauss S (2008)
    Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases
    DNA Repair (Amst), 8 (3), 298-308
    DOI 10.1016/j.dnarep.2008.11.011, PubMed 19071233

 
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