Publications 2026

Dyhr E, Cañete de Pinedo L, Frederiksen N, Bojer MS, Ingmer H, Sæbø IP, Ræder SB, Bjørås M, Helgesen E, Booth JA, Franzyk H (2026)
Antibacterial peptidomimetics via fragment display on small-molecule scaffolds
RSC Med Chem, 17 (4), 1989-2001 (in press)
DOI 10.1039/d5md00916b, PubMed 41782641

Dyhr E, Sæbø IP, Riisnæs IMM, Bjørås M, Helgesen E, Booth JA, Franzyk H (2026)
Antimicrobial Peptides Based on the TisB Toxin: Toward Enhanced Activity and Synergy with Antibiotics
ACS Omega, 11 (26), 38837-38847
DOI 10.1021/acsomega.6c02137, PubMed 42428866

Riisnæs IMM, Ræder SB, Simonsen S, Vikedal K, Backe PH, Johnsen L, Bjørås M, Booth JA, Kragelund BB, Skarstad K, Helgesen E (2026)
The RecBCD complex interacts directly with the DNA sliding clamp in Escherichia coli
Nucleic Acids Res, 54 (11)
DOI 10.1093/nar/gkag570, PubMed 42273914

Vikedal K, Berges N, Riisnæs IMM, Ræder SB, Bjørnholt JV, Bjørås M, Skarstad K, Helgesen E, Booth JA (2026)
Exploring the genetic landscape of ciprofloxacin-induced DNA supercompaction in Escherichia coli
Nucleic Acids Res, 54 (12)
DOI 10.1093/nar/gkag573, PubMed 42328795

Publications 2025

Dyhr E, Sæbo̷ IP, Riisnæs IMM, Bjo̷rås M, Helgesen E, Booth JA, Franzyk H (2025)
Rational Design of Antimicrobial Peptides Based on Bacterial Type‑I Toxins AapA1, IbsC, and Fst1
ACS Omega, 10 (24), 25790-25800
DOI 10.1021/acsomega.5c01863, PubMed 40584331

Lobie TA, Krog CS, Skarstad K, Bjørås M, Booth JA (2025)
Escherichia coli type I toxin TisB exclusively controls proton depolarization following antibiotic induced DNA damage
Sci Rep, 15 (1), 12774
DOI 10.1038/s41598-025-96136-x, PubMed 40229382

Roque-Borda CA, Ramirez Delgado OJ, Duran Gleriani Primo LM, Dyhr E, Sæbø IP, Helgesen E, Booth J, Franzyk H, Hansen PR, Morales-Navarrete H, de la Torre BG, Albericio F, Perdigão J, Pavan FR (2025)
Integrating Docking, Dynamics, and Assays to Predict Antimicrobial Peptide Interactions with Mycolic Acid Membranes in Mycobacterium tuberculosis
ACS Meas Sci Au, 5 (6), 981-1000
DOI 10.1021/acsmeasuresciau.5c00126, PubMed 41425329

Sæbø IP, Dyhr E, Riisnæs IMM, Franzyk H, Bjørås M, Booth JA, Helgesen E (2025)
Rational design of synthetic antimicrobial peptides based on the Escherichia coli ShoB toxin
Sci Rep, 15 (1), 14354
DOI 10.1038/s41598-025-98330-3, PubMed 40274891

Vikedal K, Ræder SB, Riisnæs IMM, Bjørås M, Booth JA, Skarstad K, Helgesen E (2025)
RecN and RecA orchestrate an ordered DNA supercompaction response following ciprofloxacin-induced DNA damage in Escherichia coli
Nucleic Acids Res, 53 (10)
DOI 10.1093/nar/gkaf437, PubMed 40433982

Publications 2023

Sæbø IP, Bjørås M, Franzyk H, Helgesen E, Booth JA (2023)
Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity
Int J Mol Sci, 24 (3)
DOI 10.3390/ijms24032914, PubMed 36769243

Thorfinnsdottir LB, Bø GH, Booth JA, Bruheim P (2023)
Survival of Escherichia coli after high-antibiotic stress is dependent on both the pregrown physiological state and incubation conditions
Front Microbiol, 14, 1149978
DOI 10.3389/fmicb.2023.1149978, PubMed 36970700

Publications 2021

Lobie TA, Roba AA, Booth JA, Kristiansen KI, Aseffa A, Skarstad K, Bjørås M (2021)
Antimicrobial resistance: A challenge awaiting the post-COVID-19 era
Int J Infect Dis, 111, 322-325
DOI 10.1016/j.ijid.2021.09.003, PubMed 34508864

Publications 2020

Booth JA, Špírek M, Lobie TA, Skarstad K, Krejci L, Bjørås M (2020)
Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability
Sci Rep, 10 (1), 19422
DOI 10.1038/s41598-020-76426-2, PubMed 33173044

Publications 2016

Kristiansen KI, Weel-Sneve R, Booth JA, Bjørås M (2016)
Mutually exclusive RNA secondary structures regulate translation initiation of DinQ in Escherichia coli
RNA, 22 (11), 1739-1749
DOI 10.1261/rna.058461.116, PubMed 27651528

Publications 2014

Booth JA, Suganthan R, Gaustad P, Bjørås M (2014)
Development of DinQ from Escherichia coli as an anti-cell-envelope antibiotic
Int J Antimicrob Agents, 45 (2), 196-7
DOI 10.1016/j.ijantimicag.2014.10.005, PubMed 25465525

Publications 2013

Booth JA, Thomassen GO, Rowe AD, Weel-Sneve R, Lagesen K, Kristiansen KI, Bjørås M, Rognes T, Lindvall JM (2013)
Tiling array study of MNNG treated Escherichia coli reveals a widespread transcriptional response
Sci Rep, 3, 3053
DOI 10.1038/srep03053, PubMed 24157950

Weel-Sneve R, Kristiansen KI, Odsbu I, Dalhus B, Booth J, Rognes T, Skarstad K, Bjørås M (2013)
Single transmembrane peptide DinQ modulates membrane-dependent activities
PLoS Genet, 9 (2), e1003260
DOI 10.1371/journal.pgen.1003260, PubMed 23408903

Publications 2010

Thomassen GO, Weel-Sneve R, Rowe AD, Booth JA, Lindvall JM, Lagesen K, Kristiansen KI, Bjørås M, Rognes T (2010)
Tiling array analysis of UV treated Escherichia coli predicts novel differentially expressed small peptides
PLoS One, 5 (12), e15356
DOI 10.1371/journal.pone.0015356, PubMed 21203457

Publications 2008

Olsen PA, Solhaug A, Booth JA, Gelazauskaite M, Krauss S (2008)
Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases
DNA Repair (Amst), 8 (3), 298-308
DOI 10.1016/j.dnarep.2008.11.011, PubMed 19071233