Publications by Kjetil Wessel Andressen

24 publications found

  1. Brudeli B, Navaratnarajah M, Andressen KW, Manfra O, Moltzau LR, Nilsen NO, Levy FO, Klaveness J (2014)
    Discovery and pharmacological profile of new hydrophilic 5-HT4 receptor antagonists
    Bioorg. Med. Chem. Lett., 24 (18), 4598-4602
    DOI 10.1016/j.bmcl.2014.06.083
  2. Brudeli B, Moltzau LR, Andressen KW, Krobert KA, Klaveness J, Levy FO (2010)
    Synthesis and pharmacological properties of novel hydrophilic 5-HT4 receptor antagonists
    Bioorg. Med. Chem., 18 (24), 8600-8613
    DOI 10.1016/j.bmc.2010.10.011
  3. Jang W, Adams CE, Liu H, Zhang C, Levy FO, Andressen KW, Lambert NA (2020)
    An inactive receptor-G protein complex maintains the dynamic range of agonist-induced signaling
    Proc. Natl. Acad. Sci. U. S. A., 117 (48), 30755-30762
    DOI 10.1073/pnas.2010801117
  4. Andressen KW, Manfra O, Brevik CH, Ulsund AH, Vanhoenacker P, Levy FO, Krobert KA (2015)
    The atypical antipsychotics clozapine and olanzapine promote down-regulation and display functional selectivity at human 5-HT7 receptors
    Br. J. Pharmacol., 172 (15), 3846-3860
    DOI 10.1111/bph.13169
  5. Brudeli B, Andressen KW, Moltzau LR, Nilsen NO, Levy FO, Klaveness J (2013)
    Acidic biphenyl derivatives: Synthesis and biological activity of a new series of potent 5-HT4 receptor antagonists
    Bioorg. Med. Chem., 21 (22), 7134-7145
    DOI 10.1016/j.bmc.2013.09.004
  6. Gellynck E, Laenen K, Andressen KW, Lintermans B, De Martelaere K, Matthys A, Levy FO, Haegeman G, Vanhoenacker P, Van Craenenbroeck K (2008)
    Cloning, genomic organization and functionality of 5-HT7 receptor splice variants from mouse brain
    Gene, 426 (1-2), 23-31
    DOI 10.1016/j.gene.2008.08.011
  7. Andressen KW, Ulsund AH, Krobert KA, Lohse MJ, Bunemann M, Levy FO (2018)
    Related GPCRs couple differently to G(s): preassociation between G protein and 5-HT7 serotonin receptor reveals movement of Gas upon receptor activation
    Faseb J., 32 (2), 1059-1069
    DOI 10.1096/fj.201700486R
  8. Orstavik O, Manfra O, Andressen KW, Andersen GO, Skomedal T, Osnes JB, Levy FO, Krobert KA (2015)
    The Inotropic Effect of the Active Metabolite of Levosimendan, OR-1896, Is Mediated through Inhibition of PDE3 in Rat Ventricular Myocardium
    PLoS One, 10 (3), e0115547
    DOI 10.1371/journal.pone.0115547
  9. Gellynck E, Andressen KW, Lintermans B, Haegeman G, Levy FO, Vanhoenacker P, Van Craenenbroeck K (2012)
    Biochemical and pharmacological study of N-linked glycosylation of the human serotonin 5-HT7(a) receptor
    FEBS J., 279 (11), 1994-2003
    DOI 10.1111/j.1742-4658.2012.08581.x
  10. Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, Sejersted OM, Sjaastad I, Stokke MK (2021)
    Exercise Training Stabilizes RyR2-Dependent Ca2+ Release in Post-infarction Heart Failure
    Front. Cardiovasc. Med., 7, 623922
    DOI 10.3389/fcvm.2020.623922
  11. Manfra O, Van Craenenbroeck K, Skieterska K, Frimurer T, Schwartz TW, Levy FO, Andressen KW (2015)
    Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1
    ACS Chem. Neurosci., 6 (7), 1206-1218
    DOI 10.1021/cn500339p
  12. Olberg DE, Andressen KW, Levy FO, Klaveness J, Haraldsen I, Sutcliffe JL (2014)
    Synthesis and in vitro evaluation of small-molecule [F-18] labeled gonadotropin-releasing hormone (GnRH) receptor antagonists as potential PET imaging agents for GnRH receptor expression
    Bioorg. Med. Chem. Lett., 24 (7), 1846-1850
    DOI 10.1016/j.bmcl.2014.02.002
  13. Afzal F, Andressen KW, Mork HK, Aronsen JM, Sjaastad I, Dahl CP, Skomedal T, Levy FO, Osnes JB, Qvigstad E (2008)
    5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles
    Br. J. Pharmacol., 155 (7), 1005-1014
    DOI 10.1038/bjp.2008.339
  14. Ulsund AH, Dahl M, Frimurer TM, Manfra O, Schwartz TW, Levy FO, Andressen KW (2019)
    Preassociation between the 5-HT7 serotonin receptor and G protein G(s): molecular determinants and association with low potency activation of adenylyl cyclase
    Faseb J., 33 (3), 3870-3886
    DOI 10.1096/fj.201800805RR
  15. Olberg DE, Hausner SH, Bauer N, Klaveness J, Indrevoll B, Andressen KW, Dahl M, Levy FO, Sutcliffe JL, Haraldsen I (2015)
    Radiosynthesis of high affinity fluorine-18 labeled GnRH peptide analogues: in vitro studies and in vivo assessment of brain uptake in rats
    MedChemComm, 6 (4), 708-714
    DOI 10.1039/c4md00486h
  16. Brudeli B, Moltzau LR, Nguyen CHT, Andressen KW, Nilsen NO, Levy FO, Klaveness J (2013)
    Synthesis and pharmacological properties of a new hydrophilic and orally bioavailable 5-HT4 antagonist
    Eur. J. Med. Chem., 64, 629-637
    DOI 10.1016/j.ejmech.2013.03.060
  17. Olberg DE, Bauer N, Andressen KW, Hjornevik T, Cumming P, Levy FO, Klaveness J, Haraldsen I, Sutcliffe JL (2016)
    Brain penetrant small molecule F-18-GnRH receptor (GnRH-R) antagonists: Synthesis and preliminary positron emission tomography imaging in rats
    Nucl. Med. Biol., 43 (8), 478-489
    DOI 10.1016/j.nucmedbio.2016.05.003
  18. Kilander MBC, Petersen J, Andressen KW, Ganji RS, Levy FO, Schuster J, Dahl N, Bryja V, Schulte G (2014)
    Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6
    Faseb J., 28 (5), 2293-2305
    DOI 10.1096/fj.13-246363
  19. Ngai J, Methi T, Andressen KW, Levy FO, Torgersen KM, Vang T, Wettschureck N, Tasken K (2008)
    The heterotrimeric G-protein alpha-subunit G alpha q regulates TCR-mediated immune responses through an Lck-dependent pathway
    Eur. J. Immunol., 38 (11), 3208-3218
    DOI 10.1002/eji.200838195
  20. Calamera G, Li D, Ulsund AH, Kim JJ, Neely OC, Moltzau LR, Bjornerem M, Paterson D, Kim C, Levy FO, Andressen KW (2019)
    FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons
    Commun. Biol., 2, 394
    DOI 10.1038/s42003-019-0641-x
  21. Impellizzeri AAR, Pappalardo M, Basile L, Manfra O, Andressen KW, Krobert KA, Messina A, Levy FO, Guccione S (2015)
    Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis
    Front. Behav. Neurosci., 9, 92
    DOI 10.3389/fnbeh.2015.00092
  22. Gellynck E, Heyninck K, Andressen KW, Haegeman G, Levy FO, Vanhoenacker P, Van Craenenbroeck K (2013)
    The serotonin 5-HT7 receptors: two decades of research
    Exp. Brain Res., 230 (4), 555-568
    DOI 10.1007/s00221-013-3694-y
  23. Vinge LE, Andressen KW, Attramadal T, Andersen GO, Ahmed MS, Peppel K, Koch WJ, Freedman NJ, Levy FO, Skomedal T, Osnes JB, Attramadal H (2007)
    Substrate specificities of G protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function
    Mol. Pharmacol., 72 (3), 582-591
    DOI 10.1124/mol.107.035766
  24. Meier S, Andressen KW, Aronsen JM, Sjaastad I, Hougen K, Skomedal T, Osnes JB, Qvigstad E, Levy FO, Moltzau LR (2017)
    PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
    Eur. J. Pharmacol., 812, 174-183
    DOI 10.1016/j.ejphar.2017.07.014

 
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