Publications by Ingrun Alseth

42 publications found

Publications 2022

  1. Quiles-Jiménez A, Dahl TB, Bjørås M, Alseth I, Halvorsen B, Gregersen I (2022)
    Epitranscriptome in Ischemic Cardiovascular Disease: Potential Target for Therapies
    Stroke, 53 (6), 2114-2122
    DOI 10.1161/STROKEAHA.121.037581, PubMed 35240858

Publications 2021

  1. Kong XY, Huse C, Yang K, Øgaard J, Berges N, Vik ES, Nawaz MS, Quiles-Jiménez A, Abbas A, Gregersen I, Holm S, Bjerkli V, Rashidi A, Fladeby C, Suganthan R, Sagen EL, Skjelland M, Lång A, Bøe SO, Bjørås M, Aukrust P, Alseth I, Halvorsen B, Dahl TB (2021)
    Endonuclease V Regulates Atherosclerosis Through C-C Motif Chemokine Ligand 2-Mediated Monocyte Infiltration
    J Am Heart Assoc, 10 (14), e020656
    DOI 10.1161/JAHA.120.020656, PubMed 34259011

Publications 2020

  1. Grøsvik K, Tesfahun AN, Muruzábal-Lecumberri I, Haugland GT, Leiros I, Ruoff P, Kvaløy JT, Knævelsrud I, Ånensen H, Alexeeva M, Sato K, Matsuda A, Alseth I, Klungland A, Bjelland S (2020)
    The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside
    Front Microbiol, 11, 263
    DOI 10.3389/fmicb.2020.00263, PubMed 32158436
  2. Kong XY, Vik ES, Nawaz MS, Berges N, Dahl TB, Vågbø C, Suganthan R, Segers F, Holm S, Quiles-Jiménez A, Gregersen I, Fladeby C, Aukrust P, Bjørås M, Klungland A, Halvorsen B, Alseth I (2020)
    Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma
    Nucleic Acids Res, 48 (8), 4463-4479
    DOI 10.1093/nar/gkaa115, PubMed 32083667
  3. Quiles-Jiménez A, Gregersen I, Mittelstedt Leal de Sousa M, Abbas A, Kong XY, Alseth I, Holm S, Dahl TB, Skagen K, Skjelland M, Aukrust P, Bjørås M, Halvorsen B (2020)
    N6-methyladenosine in RNA of atherosclerotic plaques: An epitranscriptomic signature of human carotid atherosclerosis
    Biochem Biophys Res Commun, 533 (4), 631-637
    DOI 10.1016/j.bbrc.2020.09.057, PubMed 33004177

Publications 2019

  1. Berges N, Nawaz MS, Børresdatter Dahl T, Hagen L, Bjørås M, Laerdahl JK, Alseth I (2019)
    Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform
    PLoS One, 14 (11), e0225081
    DOI 10.1371/journal.pone.0225081, PubMed 31703097

Publications 2018

  1. Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
    Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
    Nucleic Acids Res, 46 (22), 11698-11711
    DOI 10.1093/nar/gky846, PubMed 30247619
  2. Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
    Corrigendum: Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
    Nucleic Acids Res, 46 (22), 12188-12189
    DOI 10.1093/nar/gky1102, PubMed 30395271

Publications 2016

  1. Nawaz MS, Vik ES, Berges N, Fladeby C, Bjørås M, Dalhus B, Alseth I (2016)
    Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules
    J Biol Chem, 291 (41), 21786-21801
    DOI 10.1074/jbc.M116.730911, PubMed 27573237
  2. Nawaz MS, Vik ES, Ronander ME, Solvoll AM, Blicher P, Bjørås M, Alseth I, Dalhus B (2016)
    Crystal structure and MD simulation of mouse EndoV reveal wedge motif plasticity in this inosine-specific endonuclease
    Sci Rep, 6, 24979
    DOI 10.1038/srep24979, PubMed 27108838

Publications 2015

  1. Dalhus B, Alseth I, Bjørås M (2015)
    Structural basis for incision at deaminated adenines in DNA and RNA by endonuclease V
    Prog Biophys Mol Biol, 117 (2-3), 134-142
    DOI 10.1016/j.pbiomolbio.2015.03.005, PubMed 25824682

Publications 2014

  1. Alseth I, Dalhus B, Bjørås M (2014)
    Inosine in DNA and RNA
    Curr Opin Genet Dev, 26, 116-23
    DOI 10.1016/j.gde.2014.07.008, PubMed 25173738
  2. Yang M, Luna L, Sørbø JG, Alseth I, Johansen RF, Backe PH, Danbolt NC, Eide L, Bjørås M (2014)
    Human OXR1 maintains mitochondrial DNA integrity and counteracts hydrogen peroxide-induced oxidative stress by regulating antioxidant pathways involving p21
    Free Radic Biol Med, 77, 41-8
    DOI 10.1016/j.freeradbiomed.2014.09.003, PubMed 25236744

Publications 2013

  1. Backe PH, Simm R, Laerdahl JK, Dalhus B, Fagerlund A, Okstad OA, Rognes T, Alseth I, Kolstø AB, Bjørås M (2013)
    A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures
    J Struct Biol, 183 (1), 66-75
    DOI 10.1016/j.jsb.2013.04.007, PubMed 23623903
  2. Rosnes I, Rowe AD, Vik ES, Forstrøm RJ, Alseth I, Bjørås M, Dalhus B (2013)
    Structural basis of DNA loop recognition by endonuclease V
    Structure, 21 (2), 257-65
    DOI 10.1016/j.str.2012.12.007, PubMed 23313664
  3. Vik ES, Nawaz MS, Strøm Andersen P, Fladeby C, Bjørås M, Dalhus B, Alseth I (2013)
    Endonuclease V cleaves at inosines in RNA
    Nat Commun, 4, 2271
    DOI 10.1038/ncomms3271, PubMed 23912683

Publications 2012

  1. Dalhus B, Nilsen L, Korvald H, Huffman J, Forstrøm RJ, McMurray CT, Alseth I, Tainer JA, Bjørås M (2012)
    Sculpting of DNA at abasic sites by DNA glycosylase homolog mag2
    Structure, 21 (1), 154-166
    DOI 10.1016/j.str.2012.11.004, PubMed 23245849
  2. Fladeby C, Vik ES, Laerdahl JK, Gran Neurauter C, Heggelund JE, Thorgaard E, Strøm-Andersen P, Bjørås M, Dalhus B, Alseth I (2012)
    The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structures
    PLoS One, 7 (11), e47466
    DOI 10.1371/journal.pone.0047466, PubMed 23139746
  3. Korvald H, Falnes PØ, Laerdahl JK, Bjørås M, Alseth I (2012)
    The Schizosaccharomyces pombe AlkB homolog Abh1 exhibits AP lyase activity but no demethylase activity
    DNA Repair (Amst), 11 (5), 453-62
    DOI 10.1016/j.dnarep.2012.01.014, PubMed 22365419
  4. Vik ES, Alseth I, Forsbring M, Helle IH, Morland I, Luna L, Bjørås M, Dalhus B (2012)
    Biochemical mapping of human NEIL1 DNA glycosylase and AP lyase activities
    DNA Repair (Amst), 11 (9), 766-73
    DOI 10.1016/j.dnarep.2012.07.002, PubMed 22858590

Publications 2011

  1. Dalhus B, Forsbring M, Helle IH, Vik ES, Forstrøm RJ, Backe PH, Alseth I, Bjørås M (2011)
    Separation-of-function mutants unravel the dual-reaction mode of human 8-oxoguanine DNA glycosylase
    Structure, 19 (1), 117-27
    DOI 10.1016/j.str.2010.09.023, PubMed 21220122
  2. Korvald H, Mølstad Moe AM, Cederkvist FH, Thiede B, Laerdahl JK, Bjørås M, Alseth I (2011)
    Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones
    PLoS One, 6 (9), e25188
    DOI 10.1371/journal.pone.0025188, PubMed 21949882
  3. Nilsen L, Forstrøm RJ, Bjørås M, Alseth I (2011)
    AP endonuclease independent repair of abasic sites in Schizosaccharomyces pombe
    Nucleic Acids Res, 40 (5), 2000-9
    DOI 10.1093/nar/gkr933, PubMed 22084197
  4. Yang M, Aamodt RM, Dalhus B, Balasingham S, Helle I, Andersen P, Tønjum T, Alseth I, Rognes T, Bjørås M (2011)
    The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage
    DNA Repair (Amst), 10 (6), 595-602
    DOI 10.1016/j.dnarep.2011.03.007, PubMed 21570366

Publications 2010

  1. Laerdahl JK, Korvald H, Nilsen L, Dahl-Michelsen K, Rognes T, Bjørås M, Alseth I (2010)
    Schizosaccharomyces pombe encodes a mutated AP endonuclease 1
    DNA Repair (Amst), 10 (3), 296-305
    DOI 10.1016/j.dnarep.2010.11.014, PubMed 21193357

Publications 2009

  1. Dalhus B, Arvai AS, Rosnes I, Olsen ØE, Backe PH, Alseth I, Gao H, Cao W, Tainer JA, Bjørås M (2009)
    Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair
    Nat Struct Mol Biol, 16 (2), 138-43
    DOI 10.1038/nsmb.1538, PubMed 19136958
  2. Forsbring M, Vik ES, Dalhus B, Karlsen TH, Bergquist A, Schrumpf E, Bjørås M, Boberg KM, Alseth I (2009)
    Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma
    Carcinogenesis, 30 (7), 1147-54
    DOI 10.1093/carcin/bgp118, PubMed 19443904
  3. Olsen I, Balasingham SV, Davidsen T, Debebe E, Rødland EA, van Soolingen D, Kremer K, Alseth I, Tønjum T (2009)
    Characterization of the major formamidopyrimidine-DNA glycosylase homolog in Mycobacterium tuberculosis and its linkage to variable tandem repeats
    FEMS Immunol Med Microbiol, 56 (2), 151-61
    DOI 10.1111/j.1574-695X.2009.00562.x, PubMed 19496823

Publications 2007

  1. Dalhus B, Helle IH, Backe PH, Alseth I, Rognes T, Bjørås M, Laerdahl JK (2007)
    Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats
    Nucleic Acids Res, 35 (7), 2451-9
    DOI 10.1093/nar/gkm039, PubMed 17395642

Publications 2006

  1. Alseth I, Rognes T, Lindbäck T, Solberg I, Robertsen K, Kristiansen KI, Mainieri D, Lillehagen L, Kolstø AB, Bjørås M (2006)
    A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD
    Mol Microbiol, 59 (5), 1602-9
    DOI 10.1111/j.1365-2958.2006.05044.x, PubMed 16468998
  2. Falnes PØ, Klungland A, Alseth I (2006)
    Repair of methyl lesions in DNA and RNA by oxidative demethylation
    Neuroscience, 145 (4), 1222-32
    DOI 10.1016/j.neuroscience.2006.11.018, PubMed 17175108
  3. Nakken S, Alseth I, Rognes T (2006)
    Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in human DNA repair genes
    Neuroscience, 145 (4), 1273-9
    DOI 10.1016/j.neuroscience.2006.09.004, PubMed 17055652

Publications 2005

  1. Alseth I, Osman F, Korvald H, Tsaneva I, Whitby MC, Seeberg E, Bjørås M (2005)
    Biochemical characterization and DNA repair pathway interactions of Mag1-mediated base excision repair in Schizosaccharomyces pombe
    Nucleic Acids Res, 33 (3), 1123-31
    DOI 10.1093/nar/gki259, PubMed 15722486

Publications 2004

  1. Alseth I, Korvald H, Osman F, Seeberg E, Bjørås M (2004)
    A general role of the DNA glycosylase Nth1 in the abasic sites cleavage step of base excision repair in Schizosaccharomyces pombe
    Nucleic Acids Res, 32 (17), 5119-25
    DOI 10.1093/nar/gkh851, PubMed 15452279

Publications 2003

  1. Maclean MJ, Aamodt R, Harris N, Alseth I, Seeberg E, Bjørås M, Piper PW (2003)
    Base excision repair activities required for yeast to attain a full chronological life span
    Aging Cell, 2 (2), 93-104
    DOI 10.1046/j.1474-9728.2003.00041.x, PubMed 12882322
  2. Osman F, Bjørås M, Alseth I, Morland I, McCready S, Seeberg E, Tsaneva I (2003)
    A new Schizosaccharomyces pombe base excision repair mutant, nth1, reveals overlapping pathways for repair of DNA base damage
    Mol Microbiol, 48 (2), 465-80
    DOI 10.1046/j.1365-2958.2003.03440.x, PubMed 12675805

Publications 2000

  1. Seeberg E, Luna L, Morland I, Eide L, Johnsen B, Larsen E, Alseth I, Dantzer F, Baynton K, Aamodt R, Kristiansen KI, Rognes T, Klungland A, Bjørås M (2000)
    Base removers and strand scissors: different strategies employed in base excision and strand incision at modified base residues in DNA
    Cold Spring Harb Symp Quant Biol, 65, 135-42
    DOI 10.1101/sqb.2000.65.135, PubMed 12760028

Publications 1999

  1. Alseth I, Eide L, Pirovano M, Rognes T, Seeberg E, Bjørås M (1999)
    The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast
    Mol Cell Biol, 19 (5), 3779-87
    DOI 10.1128/MCB.19.5.3779, PubMed 10207101
  2. Luna L, Bjoras M, Berdal KG, Alseth I, Eide L, Rognes T, Seeberg E (1999)
    Genes and enzymes for the removal of oxidative DNA base damage
    ALFRED BENZON SYMP S, 44, 272-283

Publications 1996

  1. Eide L, Bjørås M, Pirovano M, Alseth I, Berdal KG, Seeberg E (1996)
    Base excision of oxidative purine and pyrimidine DNA damage in Saccharomyces cerevisiae by a DNA glycosylase with sequence similarity to endonuclease III from Escherichia coli
    Proc Natl Acad Sci U S A, 93 (20), 10735-40
    DOI 10.1073/pnas.93.20.10735, PubMed 8855249

Publications 1995

  1. Mol CD, Arvai AS, Slupphaug G, Kavli B, Alseth I, Krokan HE, Tainer JA (1995)
    Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis
    Cell, 80 (6), 869-78
    DOI 10.1016/0092-8674(95)90290-2, PubMed 7697717

Publications 1993

  1. Slupphaug G, Alseth I, Eftedal I, Volden G, Krokan HE (1993)
    Low incorporation of dUMP by some thermostable DNA polymerases may limit their use in PCR amplifications
    Anal Biochem, 211 (1), 164-9
    DOI 10.1006/abio.1993.1248, PubMed 8323030

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