Kjell Heuser

  • Senior Consultant Neurologist and Postdoc; MD, PhD
 

Publications 2024

Enger R, Heuser K (2024)
Astrocytes as critical players of the fine balance between inhibition and excitation in the brain: spreading depolarization as a mechanism to curb epileptic activity
Front Netw Physiol, 4, 1360297
DOI 10.3389/fnetp.2024.1360297, PubMed 38405021

Heuser K, Horn M, Samsonsen C, Ulvin LB, Olsen KB, Power KN, Veiby G, Molteberg E, Engelsen B, Taubøll E (2024)
Treating status epilepticus in adults
Tidsskr Nor Laegeforen, 144 (4)
DOI 10.4045/tidsskr.23.0782, PubMed 38506004

Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2024)
Dissecting the Shared Genetic Architecture of Common Epilepsies With Cortical Brain Morphology
Neurol Genet, 10 (3), e200143
DOI 10.1212/NXG.0000000000200143, PubMed 38817246

Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Ueland T, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2024)
Unraveling the shared genetics of common epilepsies and general cognitive ability
medRxiv
DOI 10.1101/2024.03.25.24304773, PubMed 38585944

Karadag N, Hagen E, Shadrin AA, van der Meer D, O'Connell KS, Rahman Z, Kutrolli G, Parker N, Bahrami S, Fominykh V, Heuser K, Taubøll E, Ueland T, Steen NE, Djurovic S, Dale AM, Frei O, Andreassen OA, Smeland OB (2024)
Unraveling the shared genetics of common epilepsies and general cognitive ability
Seizure, 122, 105-112
DOI 10.1016/j.seizure.2024.09.016, PubMed 39388989

Ulvin LB, Nilsen KB, Taubøll E, Etholm L, Heuser K (2024)
Sensitivity and specificity of the Salzburg EEG criteria for nonconvulsive status epilepticus
Ann Clin Transl Neurol, 11 (10), 2685-2695
DOI 10.1002/acn3.52184, PubMed 39186316

Publications 2023

Bojarskaite L, Vallet A, Bjørnstad DM, Gullestad Binder KM, Cunen C, Heuser K, Kuchta M, Mardal KA, Enger R (2023)
Sleep cycle-dependent vascular dynamics in male mice and the predicted effects on perivascular cerebrospinal fluid flow and solute transport
Nat Commun, 14 (1), 953
DOI 10.1038/s41467-023-36643-5, PubMed 36806170

Hatlestad-Hall C, Bruña R, Liljeström M, Renvall H, Heuser K, Taubøll E, Maestú F, Haraldsen IH (2023)
Reliable evaluation of functional connectivity and graph theory measures in source-level EEG: How many electrodes are enough?
Clin Neurophysiol, 150, 1-16
DOI 10.1016/j.clinph.2023.03.002, PubMed 36972647

Henning O, Heuser K, Larsen VS, Kyte EB, Kostov H, Marthinsen PB, Egge A, Alfstad KÅ, Nakken KO (2023)
Temporal lobe epilepsy
Tidsskr Nor Laegeforen, 143 (2)
DOI 10.4045/tidsskr.22.0369, PubMed 36718887

Heuser K, Henning O, Nakken KO (2023)
[Epilepsy – potential for improving patient care]
Tidsskr Nor Laegeforen, 143 (8)
DOI 10.4045/tidsskr.23.0218, PubMed 37254988

Horn MA, Hov MR, Heuser K, Taubøll E (2023)
Time To Control-A goal in seizure management
Seizure, 106, 76
DOI 10.1016/j.seizure.2023.02.008, PubMed 36774777

Horn MA, Hov MR, Heuser K, Taubøll E (2023)
[‘Time to control’ as a quality indicator in seizure management]
Tidsskr Nor Laegeforen, 143 (9)
DOI 10.4045/tidsskr.23.0230, PubMed 37341400

Næsgaard JAR, Gjerstad L, Heuser K, Taubøll E (2023)
Biological rhythms and epilepsy treatment
Front Neurol, 14, 1153975
DOI 10.3389/fneur.2023.1153975, PubMed 37638185

Publications 2022

Bakhtiari A, Bjørke AB, Larsson PG, Olsen KB, Nævra MCJ, Taubøll E, Heuser K, Østby Y (2022)
Episodic Memory Dysfunction and Effective Connectivity in Adult Patients With Newly Diagnosed Nonlesional Temporal Lobe Epilepsy
Front Neurol, 13, 774532
DOI 10.3389/fneur.2022.774532, PubMed 35222242

Berger TC, Taubøll E, Heuser K (2022)
The potential role of DNA methylation as preventive treatment target of epileptogenesis
Front Cell Neurosci, 16, 931356
DOI 10.3389/fncel.2022.931356, PubMed 35936496

Heuser K, Olsen KB, Ulvin LB, Gjerstad L, Taubøll E (2022)
Modern Treatment of Status Epilepticus in Adults
In Epilepsy (Stanislaw J. Czuczwar, ed.), Exon Publications, Brisbane, Australia, 55-78
DOI 10.36255/exon-publications-epilepsy-status-epilepticus, PublikaID 429, ISBN 978-0-6453320-4-9

Roberg LE, Monsson O, Kristensen SB, Dahl SM, Ulvin LB, Heuser K, Taubøll E, Strzelczyk A, Knake S, Bechert L, Rosenow F, Beier D, Beniczky S, Krøigård T, Beier CP (2022)
Prediction of Long-term Survival After Status Epilepticus Using the ACD Score
JAMA Neurol, 79 (6), 604-613
DOI 10.1001/jamaneurol.2022.0609, PubMed 35404392

Publications 2021

Bjørke AB, Østby Y, Grahl SG, Larsson PG, Olsen KB, Johansen Nævra MC, Ringstad GA, Bjørnerud A, Gjerstad L, Taubøll E, Heuser K (2021)
Cognition in adult patients with newly diagnosed non-lesional temporal lobe epilepsy
Epilepsy Behav, 116, 107771
DOI 10.1016/j.yebeh.2021.107771, PubMed 33545650

Hatlestad-Hall C, Bruña R, Erichsen A, Andersson V, Syvertsen MR, Skogan AH, Renvall H, Marra C, Maestú F, Heuser K, Taubøll E, Solbakk AK, Haraldsen IH (2021)
The organization of functional neurocognitive networks in focal epilepsy correlates with domain-specific cognitive performance
J Neurosci Res, 99 (10), 2669-2687
DOI 10.1002/jnr.24896, PubMed 34173259

Heuser K, Berger TC, Henning O, Svalheim S, Sibeko JM, Nakken KO, Taubøll E (2021)
COVID-19 and epilepsy
Tidsskr Nor Laegeforen, 141 (10)
DOI 10.4045/tidsskr.21.0429, PubMed 34182721

Heuser K, de Curtis M, Steinhäuser C (2021)
Editorial: Glial Dysfunction in Epileptogenesis
Front Neurol, 12, 716308
DOI 10.3389/fneur.2021.716308, PubMed 34326808

Heuser K, Enger R (2021)
Astrocytic Ca2+ Signaling in Epilepsy
Front Cell Neurosci, 15, 695380
DOI 10.3389/fncel.2021.695380, PubMed 34335188

Heuser K, Enger R, Berger T, Taubøll E (2021)
[New routes to take for better epilepsy treatment]
Tidsskr Nor Laegeforen, 141 (10)
DOI 10.4045/tidsskr.21.0469, PubMed 34182732

Mochol M, Taubøll E, Sveberg L, Tennøe B, Berg Olsen K, Heuser K, Svalheim S (2021)
Seizure control after late introduction of anakinra in a patient with adult onset Rasmussen's encephalitis
Epilepsy Behav Rep, 16, 100462
DOI 10.1016/j.ebr.2021.100462, PubMed 34189453

Publications 2020

Berger TC, Vigeland MD, Hjorthaug HS, Nome CG, Taubøll E, Selmer KK, Heuser K (2020)
Differential Glial Activation in Early Epileptogenesis-Insights From Cell-Specific Analysis of DNA Methylation and Gene Expression in the Contralateral Hippocampus
Front Neurol, 11, 573575
DOI 10.3389/fneur.2020.573575, PubMed 33312155

González A, Nome CG, Bendiksen BA, Sjaastad I, Zhang L, Aleksandersen M, Taubøll E, Aurlien D, Heuser K (2020)
Assessment of cardiac structure and function in a murine model of temporal lobe epilepsy
Epilepsy Res, 161, 106300
DOI 10.1016/j.eplepsyres.2020.106300, PubMed 32126491

Habhab SF, Ulvin LB, Taubøll E, Svalheim S, Olsen KB, Horn MA, Heuser K (2020)
Influence of valproate-induced hyperammonemia on treatment decision in an adult status epilepticus cohort
Epilepsy Behav, 111, 107193
DOI 10.1016/j.yebeh.2020.107193, PubMed 32759060

Publications 2019

Berger TC, Vigeland MD, Hjorthaug HS, Etholm L, Nome CG, Taubøll E, Heuser K, Selmer KK (2019)
Neuronal and glial DNA methylation and gene expression changes in early epileptogenesis
PLoS One, 14 (12), e0226575
DOI 10.1371/journal.pone.0226575, PubMed 31887157

Ulvin LB, Taubøll E, Olsen KB, Heuser K (2019)
Predictive performances of STESS and EMSE in a Norwegian adult status epilepticus cohort
Seizure, 70, 6-11
DOI 10.1016/j.seizure.2019.06.024, PubMed 31229856

Publications 2018

Bjørke AB, Nome CG, Falk RS, Gjerstad L, Taubøll E, Heuser K (2018)
Evaluation of long-term antiepileptic drug use in patients with temporal lobe epilepsy: Assessment of risk factors for drug resistance and polypharmacy
Seizure, 61, 63-70
DOI 10.1016/j.seizure.2018.07.011, PubMed 30099235

Eidsvaag VA, Hansson HA, Heuser K, Nagelhus EA, Eide PK (2018)
Cerebral microvascular abnormalities in patients with idiopathic intracranial hypertension
Brain Res, 1686, 72-82
DOI 10.1016/j.brainres.2018.02.017, PubMed 29477544

Heuser K, Nome CG, Pettersen KH, Åbjørsbråten KS, Jensen V, Tang W, Sprengel R, Taubøll E, Nagelhus EA, Enger R (2018)
Ca2+ Signals in Astrocytes Facilitate Spread of Epileptiform Activity
Cereb Cortex, 28 (11), 4036-4048
DOI 10.1093/cercor/bhy196, PubMed 30169757

Ulvin LB, Heuser K, Olsen KB, Taubøll E (2018)
Factors associated with refractoriness and outcome in an adult status epilepticus cohort
Seizure, 61, 111-118
DOI 10.1016/j.seizure.2018.07.020, PubMed 30125862

Publications 2017

Eidsvaag VA, Hansson HA, Heuser K, Nagelhus EA, Eide PK (2017)
Brain Capillary Ultrastructure in Idiopathic Normal Pressure Hydrocephalus: Relationship With Static and Pulsatile Intracranial Pressure
J Neuropathol Exp Neurol, 76 (12), 1034-1045
DOI 10.1093/jnen/nlx091, PubMed 29040647

Publications 2016

Heuser K, Nakken KO, Sandvig I, Taubøll E (2016)
[What causes febrile convulsions?]
Tidsskr Nor Laegeforen, 136 (1), 36-8
DOI 10.4045/tidsskr.14.1503, PubMed 26757658

Publications 2015

Szokol K, Heuser K, Tang W, Jensen V, Enger R, Bedner P, Steinhäuser C, Taubøll E, Ottersen OP, Nagelhus EA (2015)
Augmentation of Ca(2+) signaling in astrocytic endfeet in the latent phase of temporal lobe epilepsy
Front Cell Neurosci, 9, 49
DOI 10.3389/fncel.2015.00049, PubMed 25762896

Tauboll E, Heuser K, Sveberg L, Svalheim S (2015)
Experimental models for the study of hormonal changes in epilepsy
Z. Epileptol., 28 (4), 246-253
DOI 10.1007/s10309-015-0001-x

Publications 2014

Hessel EV, de Wit M, Wolterink-Donselaar IG, Karst H, de Graaff E, van Lith HA, de Bruijn E, de Sonnaville S, Verbeek NE, Lindhout D, de Kovel CG, Koeleman BP, van Kempen M, Brilstra E, Cuppen E, Loos M, Spijker SS, Kan AA, Baars SE, van Rijen PC, Gosselaar PH, Groot Koerkamp MJ, Holstege FC, van Duijn C, Vergeer J et al. (2014)
Identification of Srp9 as a febrile seizure susceptibility gene
Ann Clin Transl Neurol, 1 (4), 239-50
DOI 10.1002/acn3.48, PubMed 25590037

Heuser K, Szokol K, Taubøll E (2014)
The role of glial cells in epilepsy
Tidsskr Nor Laegeforen, 134 (1), 37-41
DOI 10.4045/tidsskr.12.1344, PubMed 24429754

Lorentzen AO, Sveberg L, Midtvedt Ø, Kerty E, Heuser K (2014)
Overnight response to infliximab in neurosarcoidosis: a case report and review of infliximab treatment practice
Clin Neuropharmacol, 37 (5), 142-8
DOI 10.1097/WNF.0000000000000047, PubMed 25229171

Nakken KO, Heuser K, Alfstad K, Taubøll E (2014)
[How do antiepileptic drugs work?]
Tidsskr Nor Laegeforen, 134 (1), 42-6
DOI 10.4045/tidsskr.13.0761, PubMed 24429755

Vik-Mo EO, Krossnes BK, Stanisic M, Egge A, Holter E, Taubøll E, Heuser K, Lund CG (2014)
Reactivation of occult herpes simplex meningoencephalitis after temporal lobe resection for refractory epilepsy--a case report
Seizure, 23 (4), 321-3
DOI 10.1016/j.seizure.2014.01.010, PubMed 24521759

Publications 2012

Heuser K, Eid T, Lauritzen F, Thoren AE, Vindedal GF, Taubøll E, Gjerstad L, Spencer DD, Ottersen OP, Nagelhus EA, de Lanerolle NC (2012)
Loss of perivascular Kir4.1 potassium channels in the sclerotic hippocampus of patients with mesial temporal lobe epilepsy
J Neuropathol Exp Neurol, 71 (9), 814-25
DOI 10.1097/NEN.0b013e318267b5af, PubMed 22878665

Lauritzen F, Heuser K, de Lanerolle NC, Lee TS, Spencer DD, Kim JH, Gjedde A, Eid T, Bergersen LH (2012)
Redistribution of monocarboxylate transporter 2 on the surface of astrocytes in the human epileptogenic hippocampus
Glia, 60 (7), 1172-81
DOI 10.1002/glia.22344, PubMed 22535546

Publications 2011

Kerty E, Heuser K, Indahl UG, Berg PR, Nakken S, Lien S, Omholt SW, Ottersen OP, Nagelhus EA (2011)
Is the brain water channel aquaporin-4 a pathogenetic factor in idiopathic intracranial hypertension? Results from a combined clinical and genetic study in a Norwegian cohort
Acta Ophthalmol, 91 (1), 88-91
DOI 10.1111/j.1755-3768.2011.02231.x, PubMed 21914143

Publications 2010

Heuser K, Cvancarova M, Gjerstad L, Taubøll E (2010)
Is Temporal Lobe Epilepsy with childhood febrile seizures a distinctive entity? A comparative study
Seizure, 20 (2), 163-6
DOI 10.1016/j.seizure.2010.11.015, PubMed 21167748

Heuser K, Hoddevik EH, Taubøll E, Gjerstad L, Indahl U, Kaczmarek L, Berg PR, Lien S, Nagelhus EA, Ottersen OP (2010)
Temporal lobe epilepsy and matrix metalloproteinase 9: a tempting relation but negative genetic association
Seizure, 19 (6), 335-8
DOI 10.1016/j.seizure.2010.05.003, PubMed 20605480

Kasperaviciūte D, Catarino CB, Heinzen EL, Depondt C, Cavalleri GL, Caboclo LO, Tate SK, Jamnadas-Khoda J, Chinthapalli K, Clayton LM, Shianna KV, Radtke RA, Mikati MA, Gallentine WB, Husain AM, Alhusaini S, Leppert D, Middleton LT, Gibson RA, Johnson MR, Matthews PM, Hosford D, Heuser K, Amos L, Ortega M et al. (2010)
Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study
Brain, 133 (Pt 7), 2136-47
DOI 10.1093/brain/awq130, PubMed 20522523

Publications 2009

Heuser K, Nagelhus EA, Taubøll E, Indahl U, Berg PR, Lien S, Nakken S, Gjerstad L, Ottersen OP (2009)
Variants of the genes encoding AQP4 and Kir4.1 are associated with subgroups of patients with temporal lobe epilepsy
Epilepsy Res, 88 (1), 55-64
DOI 10.1016/j.eplepsyres.2009.09.023, PubMed 19864112

Heuser K, Taubøll E, Nagelhus EA, Cvancarova M, Petter Ottersen O, Gjerstad L (2009)
Phenotypic characteristics of temporal lobe epilepsy: the impact of hippocampal sclerosis
Acta Neurol Scand Suppl (189), 8-13
DOI 10.1111/j.1600-0404.2009.01205.x, PubMed 19566491

Publications 2007

Heuser K, Kerty E, Eide PK, Cvancarova M, Dietrichs E (2007)
Microvascular decompression for hemifacial spasm: postoperative neurologic follow-up and evaluation of life quality
Eur J Neurol, 14 (3), 335-40
DOI 10.1111/j.1468-1331.2006.01670.x, PubMed 17355557

Publications 2004

Heuser K, Kerty E (2004)
Neuro-ophthalmological findings in sarcoidosis
Acta Ophthalmol Scand, 82 (6), 723-9
DOI 10.1111/j.1600-0420.2004.00348.x, PubMed 15606471

Küchler R, Gegenwart P, Heuser K, Scheidt EW, Stewart GR, Steglich F (2004)
Grüneisen ratio divergence at the quantum critical point in CeCu(6-x)Agx
Phys Rev Lett, 93 (9), 096402
DOI 10.1103/PhysRevLett.93.096402, PubMed 15447119

Publications 2001

Kraus JA, Wenghoefer M, Glesmann N, Mohr S, Beck M, Schmidt MC, Schröder R, Berweiler U, Roggendorf W, Diete S, Dietzmann K, Heuser K, Müller B, Fimmers R, von Deimling A, Schlegel U (2001)
TP53 gene mutations, nuclear p53 accumulation, expression of Waf/p21, Bcl-2, and CD95 (APO-1/Fas) proteins are not prognostic factors in de novo glioblastoma multiforme
J Neurooncol, 52 (3), 263-72
DOI 10.1023/a:1010684203704, PubMed 11519857

Publications 2000

Kraus JA, Wenghoefer M, Schmidt MC, von Deimling A, Berweiler U, Roggendorf W, Diete S, Dietzmann K, Müller B, Heuser K, Reifenberger G, Schlegel U (2000)
Long-term survival of glioblastoma multiforme: importance of histopathological reevaluation
J Neurol, 247 (6), 455-60
DOI 10.1007/s004150070175, PubMed 10929275

Publications 1998

Schlüter E, Heuser K (1998)
Dramatic development of quadriplegia in a young man while engaged in heavy manual labour: a post-traumatic spinal cord injury?
Virchows Arch, 433 (5), 487-91
DOI 10.1007/s004280050278, PubMed 9849865

Publications 1996

Link J, Brinkmann G, Heuser K, Heller M (1996)
[CT and PRI angiographic findings in dissection of the neck arteries]
Rofo, 165 (3), 244-8
PubMed 8924684

Publications 1990

Heuser K (1990)
[Chemotherapy in malignant gliomas]
Neurochirurgia (Stuttg), 33 Suppl 1, 20-2
DOI 10.1055/s-2008-1053590, PubMed 2293042

Publications 1989

Baron R, Heuser K, Marioth G (1989)
Marchiafava-Bignami disease with recovery diagnosed by CT and MRI: demyelination affects several CNS structures
J Neurol, 236 (6), 364-6
DOI 10.1007/BF00314384, PubMed 2795107