Welcome to Per Medbøe Thorsby's research group:
Biochemical endocrinology and metabolism research group
The aim of this research group is to explore metabolic aberrations in endocrine diseases for the identification and validation of new biomarkers.
Endocrine and metabolic diseases such as diabetes, thyroid diseases, adrenal diseases and osteoporosis are major causes of morbidity and mortality.
The challenges are to identify persons at risk, implement therapeutic and preventive measures and monitor effects of these actions.
Adequate diagnostics and follow-up of treatment depend heavily on biomarkers in blood, urine, tears and saliva.
We use transcriptomic, proteomic and metabolomic approaches in close collaboration with the Dept of Endocrinology, OUS.
Finding new biomarkers:
- Proteomic / metabolomic profiling of human insulin producing cells aiming at discovering biomarkers for cell mas / function
- Posttranslational modification of albumin in diabetes and late complications of diabetes
- Thyroid disease:
- Prospective evaluation of biomarkers of tear fluid in Graves ophtalmopathy
- Metabolomic profiling of tear fluid in Graves ophtalmopathy
- Functional studies of genetic modifications in thyroid hormone resistance
- Proteomic / metabolomic profiling of human fat tissue
- Proteomic / metabolomic profiling of human bone marrow
- Gene expression of vitamin D stimulated insulin producing cells
- Metabolomic profiling of hyperglycemic clamp in humans
- Proteomic profiling of CSF in narcolepsy
- Influence of estrogen supplementations on cortisol measurements in humans
- Steroid profiling in congenital adrenal hyperplasia
Per Medbøe Thorsby, Hormone Laboratory, Department of Medical Biochemistry,
Tel: + 47 23 03 30 43/ + 47 22 89 47 08 E-mail: firstname.lastname@example.org
Growth coordination during development
Mar 27, 2017
Jørgen Wesche appointed group leader for the Mesenchymal Cancer Biology Group at the Department of Tumor Biology
Mar 15, 2017
Prestigious research prize from the Norwegian Cancer Society to pioneer in autophagy research
Mar 7, 2017
Perioperative humoral stress response to laparoscopic versus open aortobifemoral bypass surgery
Scand J Clin Lab Invest, 77 (2), 83-92
35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999
Diabetologia, 42 (Suppl 1), A1-A330
Comparison of the acute-phase response after laparoscopic versus open aortobifemoral bypass surgery: a substudy of a randomized controlled trial
Vasc Health Risk Manag, 12, 371-378