Steinar Aamdal
Position: Prof. em, MD PhD/ Head of department of Early Cancer Trials and Research Support
Phone: +47 22935706
Email:

Publications by Steinar Aamdal

107 publications found

Publications 2016

  1. Kyte JA, Gaudernack G, Faane A, Lislerud K, Inderberg EM, Brunsvig P, Aamdal S, Kvalheim G, Wälchli S, Pule M (2016)
    T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy
    Oncoimmunology, 5 (12), e1249090
    PubMed 28123886
  2. Kyte JA, Aamdal S, Dueland S, Sæbøe-Larsen S, Inderberg EM, Madsbu UE, Skovlund E, Gaudernack G, Kvalheim G (2016)
    Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells
    Oncoimmunology, 5 (11), e1232237
    PubMed 27999747
  3. Sioud M, Nyakas M, Sæbøe-Larssen S, Mobergslien A, Aamdal S, Kvalheim G (2016)
    Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine
    Case Rep Med, 2016, 9639585
    PubMed 27504122

Publications 2015

  1. Andersson Y, Engebraaten O, Juell S, Aamdal S, Brunsvig P, Fodstad Ø, Dueland S (2015)
    Phase I trial of EpCAM-targeting immunotoxin MOC31PE, alone and in combination with cyclosporin
    Br J Cancer, 113 (11), 1548-55
    PubMed 26554649
  2. Maio M, Grob JJ, Aamdal S, Bondarenko I, Robert C, Thomas L, Garbe C, Chiarion-Sileni V, Testori A, Chen TT, Tschaika M, Wolchok JD (2015)
    Five-year survival rates for treatment-naive patients with advanced melanoma who received ipilimumab plus dacarbazine in a phase III trial
    J Clin Oncol, 33 (10), 1191-6
    PubMed 25713437
  3. Prasmickaite L, Berge G, Bettum IJ, Aamdal S, Hansson J, Bastholt L, Øijordsbakken M, Boye K, Mælandsmo GM (2015)
    Evaluation of serum osteopontin level and gene polymorphism as biomarkers: analyses from the Nordic Adjuvant Interferon alpha Melanoma trial
    Cancer Immunol Immunother, 64 (6), 769-76
    PubMed 25832001
  4. Venugopal B, Awada A, Evans TR, Dueland S, Hendlisz A, Rasch W, Hernes K, Hagen S, Aamdal S (2015)
    A first-in-human phase I and pharmacokinetic study of CP-4126 (CO-101), a nucleoside analogue, in patients with advanced solid tumours
    Cancer Chemother Pharmacol, 76 (4), 785-92
    PubMed 26289594

Publications 2014

  1. Vihinen P, Tervahartiala T, Sorsa T, Hansson J, Bastholt L, Aamdal S, Stierner U, Pyrhönen S, Syrjänen K, Lundin J, Hernberg M (2014)
    Benefit of adjuvant interferon alfa-2b (IFN-α) therapy in melanoma patients with high serum MMP-8 levels
    Cancer Immunol Immunother, 64 (2), 173-80
    PubMed 25319807

Publications 2013

  1. Brandberg Y, Johansson H, Aamdal S, Bastholt L, Hernberg M, Stierner U, von der Maase H, Hansson J, Nordic Melanoma Cooperative Group (2013)
    Role functioning before start of adjuvant treatment was an independent prognostic factor for survival and time to failure. A report from the Nordic adjuvant interferon trial for patients with high-risk melanoma
    Acta Oncol, 52 (6), 1086-93
    PubMed 23621752
  2. Cohen RB, Aamdal S, Nyakas M, Cavallin M, Green D, Learoyd M, Smith I, Kurzrock R (2013)
    A phase I dose-finding, safety and tolerability study of AZD8330 in patients with advanced malignancies
    Eur J Cancer, 49 (7), 1521-9
    PubMed 23433846
  3. del Campo AB, Kyte JA, Carretero J, Zinchencko S, Méndez R, González-Aseguinolaza G, Ruiz-Cabello F, Aamdal S, Gaudernack G, Garrido F, Aptsiauri N (2013)
    Immune escape of cancer cells with beta2-microglobulin loss over the course of metastatic melanoma
    Int J Cancer, 134 (1), 102-13
    PubMed 23784959
  4. Eggermont AM, Suciu S, Rutkowski P, Marsden J, Santinami M, Corrie P, Aamdal S, Ascierto PA, Patel PM, Kruit WH, Bastholt L, Borgognoni L, Bernengo MG, Davidson N, Polders L, Praet M, Spatz A (2013)
    Adjuvant ganglioside GM2-KLH/QS-21 vaccination versus observation after resection of primary tumor > 1.5 mm in patients with stage II melanoma: results of the EORTC 18961 randomized phase III trial
    J Clin Oncol, 31 (30), 3831-7
    PubMed 24019551
  5. Geisler J, Bachmann IM, Nyakas M, Helsing P, Fjøsne HE, Mæhle LO, Aamdal S, Eide NA, Svendsen HL, Straume O, Robsahm TE, Jacobsen KD, Akslen LA (2013)
    Malignant melanoma--diagnosis, treatment and follow-up in Norway
    Tidsskr Nor Laegeforen, 133 (20), 2154-9
    PubMed 24172628
  6. Vik-Mo EO, Nyakas M, Mikkelsen BV, Moe MC, Due-Tønnesen P, Suso EM, Sæbøe-Larssen S, Sandberg C, Brinchmann JE, Helseth E, Rasmussen AM, Lote K, Aamdal S, Gaudernack G, Kvalheim G, Langmoen IA (2013)
    Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma
    Cancer Immunol Immunother, 62 (9), 1499-509
    PubMed 23817721

Publications 2012

  1. Kaye S, Aamdal S, Jones R, Freyer G, Pujade-Lauraine E, de Vries EG, Barriuso J, Sandhu S, Tan DS, Hartog V, Kuenen B, Ruijter R, Kristensen GB, Nyakas M, Barrett S, Burke W, Pietersma D, Stuart M, Emeribe U, Boven E (2012)
    Phase I study of saracatinib (AZD0530) in combination with paclitaxel and/or carboplatin in patients with solid tumours
    Br J Cancer, 106 (11), 1728-34
    PubMed 22531637

Publications 2011

  1. Brandberg Y, Aamdal S, Bastholt L, Hernberg M, Stierner U, von der Maase H, Hansson J (2011)
    Health-related quality of life in patients with high-risk melanoma randomised in the Nordic phase 3 trial with adjuvant intermediate-dose interferon alfa-2b
    Eur J Cancer, 48 (13), 2012-9
    PubMed 22196968
  2. Brunsvig PF, Kyte JA, Kersten C, Sundstrøm S, Møller M, Nyakas M, Hansen GL, Gaudernack G, Aamdal S (2011)
    Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial
    Clin Cancer Res, 17 (21), 6847-57
    PubMed 21918169
  3. Fox BA, Schendel DJ, Butterfield LH, Aamdal S, Allison JP, Ascierto PA, Atkins MB, Bartunkova J, Bergmann L, Berinstein N, Bonorino CC, Borden E, Bramson JL, Britten CM, Cao X, Carson WE, Chang AE, Characiejus D, Choudhury AR, Coukos G, de Gruijl T, Dillman RO, Dolstra H, Dranoff G, Durrant LG et al. (2011)
    Defining the critical hurdles in cancer immunotherapy
    J Transl Med, 9, 214
    PubMed 22168571
  4. Hamid O, Schmidt H, Nissan A, Ridolfi L, Aamdal S, Hansson J, Guida M, Hyams DM, Gómez H, Bastholt L, Chasalow SD, Berman D (2011)
    A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma
    J Transl Med, 9, 204
    PubMed 22123319
  5. Hansson J, Aamdal S, Bastholt L, Brandberg Y, Hernberg M, Nilsson B, Stierner U, von der Maase H, Nordic Melanoma Cooperative Group (2011)
    Two different durations of adjuvant therapy with intermediate-dose interferon alfa-2b in patients with high-risk melanoma (Nordic IFN trial): a randomised phase 3 trial
    Lancet Oncol, 12 (2), 144-52
    PubMed 21256809
  6. Kyte JA, Gaudernack G, Dueland S, Trachsel S, Julsrud L, Aamdal S (2011)
    Telomerase peptide vaccination combined with temozolomide: a clinical trial in stage IV melanoma patients
    Clin Cancer Res, 17 (13), 4568-80
    PubMed 21586625
  7. Suso EM, Dueland S, Rasmussen AM, Vetrhus T, Aamdal S, Kvalheim G, Gaudernack G (2011)
    hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
    Cancer Immunol Immunother, 60 (6), 809-18
    PubMed 21365467
  8. Zwierzina H, Bergmann L, Fiebig H, Aamdal S, Schöffski P, Witthohn K, Lentzen H (2011)
    The preclinical and clinical activity of aviscumine: a potential anticancer drug
    Eur J Cancer, 47 (10), 1450-7
    PubMed 21482461
  9. Aamdal S (2011)
    Current approaches to adjuvant therapy of melanoma
    Eur J Cancer, 47 Suppl 3, S336-7
    PubMed 21944005

Publications 2010

  1. Edvardsen H, Brunsvig PF, Solvang H, Tsalenko A, Andersen A, Syvanen AC, Yakhini Z, Børresen-Dale AL, Olsen H, Aamdal S, Kristensen VN (2010)
    SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance
    Pharmacogenomics J, 10 (6), 513-23
    PubMed 20157331
  2. Prasmickaite L, Skrbo N, Høifødt HK, Suo Z, Engebråten O, Gullestad HP, Aamdal S, Fodstad Ø, Maelandsmo GM (2010)
    Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells
    Pigment Cell Melanoma Res, 23 (3), 449-51
    PubMed 20236249

Publications 2009

  1. Bouwhuis MG, Suciu S, Collette S, Aamdal S, Kruit WH, Bastholt L, Stierner U, Salès F, Patel P, Punt CJ, Hernberg M, Spatz A, ten Hagen TL, Hansson J, Eggermont AM, EORTC Melanoma Group and the Nordic Melanoma Group (2009)
    Autoimmune antibodies and recurrence-free interval in melanoma patients treated with adjuvant interferon
    J Natl Cancer Inst, 101 (12), 869-77
    PubMed 19509353
  2. Dueland S, Aamdal S, Lind MJ, Thomas H, Sandvold ML, Gaullier JM, Rasch W (2009)
    Intravenous administration of CP-4055 (ELACYT) in patients with solid tumours. A Phase I study
    Acta Oncol, 48 (1), 137-45
    PubMed 18607882
  3. Gunnes N, Seierstad TG, Aamdal S, Brunsvig PF, Jacobsen AB, Sundstrøm S, Aalen OO (2009)
    Assessing quality of life in a randomized clinical trial: correcting for missing data
    BMC Med Res Methodol, 9, 28
    PubMed 19405936

Publications 2008

  1. Brunsvig PF, Flatmark K, Aamdal S, Høifødt H, Le H, Jakobsen E, Sandstad B, Fodstad O (2008)
    Bone marrow micrometastases in advanced stage non-small cell lung carcinoma patients
    Lung Cancer, 61 (2), 170-6
    PubMed 18261824
  2. Faye RS, Paus E, Maelandsmo GM, Berner A, Høifødt HK, Fodstad Ø, Aamdal S (2008)
    S100B in bone marrow aspirates in healthy individuals and malignant melanoma patients
    Melanoma Res, 18 (2), 134-40
    PubMed 18337650
  3. Helsing P, Nymoen DA, Ariansen S, Steine SJ, Maehle L, Aamdal S, Langmark F, Loeb M, Akslen LA, Molven A, Andresen PA (2008)
    Population-based prevalence of CDKN2A and CDK4 mutations in patients with multiple primary melanomas
    Genes Chromosomes Cancer, 47 (2), 175-84
    PubMed 18023021

Publications 2007

  1. Brunsvig PF, Andersen A, Aamdal S, Kristensen V, Olsen H (2007)
    Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy
    BMC Cancer, 7, 197
    PubMed 17956601
  2. Hernberg M, Mattila PS, Rissanen M, Hansson J, Aamdal S, Bastholt L, von der Maase H, Schmidt H, Stierner U, Tarkkanen J (2007)
    The prognostic role of blood lymphocyte subset distribution in patients with resected high-risk primary or regionally metastatic melanoma
    J Immunother, 30 (7), 773-9
    PubMed 17893569

Publications 2006

  1. Andersen A, Warren DJ, Brunsvig PF, Aamdal S, Kristensen GB, Olsen H (2006)
    High sensitivity assays for docetaxel and paclitaxel in plasma using solid-phase extraction and high-performance liquid chromatography with UV detection
    BMC Clin Pharmacol, 6, 2
    PubMed 16412237
  2. Brunsvig PF, Aamdal S, Gjertsen MK, Kvalheim G, Markowski-Grimsrud CJ, Sve I, Dyrhaug M, Trachsel S, Møller M, Eriksen JA, Gaudernack G (2006)
    Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
    Cancer Immunol Immunother, 55 (12), 1553-64
    PubMed 16491401
  3. Jacobsen KD, Fosså SD, Aamdal S (2006)
    [Malignant melanoma--diagnosis and treatment]
    Tidsskr Nor Laegeforen, 126 (23), 3094-7
    PubMed 17160112
  4. Kyte JA, Kvalheim G, Lislerud K, thor Straten P, Dueland S, Aamdal S, Gaudernack G (2006)
    T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
    Cancer Immunol Immunother, 56 (5), 659-75
    PubMed 16947019
  5. Kyte JA, Mu L, Aamdal S, Kvalheim G, Dueland S, Hauser M, Gullestad HP, Ryder T, Lislerud K, Hammerstad H, Gaudernack G (2006)
    Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
    Cancer Gene Ther, 13 (10), 905-18
    PubMed 16710345
  6. Warloe T, Aamdal S, Reith A, Bryne M (2006)
    [Retraction of: Diagnostics and treatment of early stages of oral cancer]
    Tidsskr Nor Laegeforen, 126 (17), 2287
    PubMed 16967079

Publications 2005

  1. Brunsvig PF, Hatlevoll R, Berg R, Lauvvang G, Owre K, Wang M, Aamdal S (2005)
    Weekly docetaxel with concurrent radiotherapy in locally advanced non-small cell lung cancer: a phase I/II study with 5 years' follow-up
    Lung Cancer, 50 (1), 97-105
    PubMed 16005105
  2. Kyte JA, Kvalheim G, Aamdal S, Saebøe-Larssen S, Gaudernack G (2005)
    Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
    Cancer Gene Ther, 12 (6), 579-91
    PubMed 15818380
  3. Millward MJ, Joshua A, Kefford R, Aamdal S, Thomson D, Hersey P, Toner G, Lynch K (2005)
    Multi-centre Phase II trial of the polyamine synthesis inhibitor SAM486A (CGP48664) in patients with metastatic melanoma
    Invest New Drugs, 23 (3), 253-6
    PubMed 15868382
  4. Mu LJ, Kyte JA, Kvalheim G, Aamdal S, Dueland S, Hauser M, Hammerstad H, Waehre H, Raabe N, Gaudernack G (2005)
    Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
    Br J Cancer, 93 (7), 749-56
    PubMed 16136047
  5. Smyth JF, Aamdal S, Awada A, Dittrich C, Caponigro F, Schöffski P, Gore M, Lesimple T, Djurasinovic N, Baron B, Ravic M, Fumoleau P, Punt CJ, EORTC New Drug Development and Melanoma Groups (2005)
    Phase II study of E7070 in patients with metastatic melanoma
    Ann Oncol, 16 (1), 158-61
    PubMed 15598954

Publications 2004

  1. Avril MF, Aamdal S, Grob JJ, Hauschild A, Mohr P, Bonerandi JJ, Weichenthal M, Neuber K, Bieber T, Gilde K, Guillem Porta V, Fra J, Bonneterre J, Saïag P, Kamanabrou D, Pehamberger H, Sufliarsky J, Gonzalez Larriba JL, Scherrer A, Menu Y (2004)
    Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study
    J Clin Oncol, 22 (6), 1118-25
    PubMed 15020614
  2. Bos AM, Boom K, Vinks AA, Boezen HM, Wanders J, Dombernovsky P, Aamdal S, de Vries EG, Uges DR (2004)
    Development of an optimal sampling strategy for clinical pharmacokinetic studies of the novel anthracycline disaccharide analogue MEN-10755
    Cancer Chemother Pharmacol, 54 (1), 64-70
    PubMed 15069581
  3. Cheng JD, Babb JS, Langer C, Aamdal S, Robert F, Engelhardt LR, Fernberg O, Schiller J, Forsberg G, Alpaugh RK, Weiner LM, Rogatko A (2004)
    Individualized patient dosing in phase I clinical trials: the role of escalation with overdose control in PNU-214936
    J Clin Oncol, 22 (4), 602-9
    PubMed 14966084
  4. Faye RS, Aamdal S, Høifødt HK, Jacobsen E, Holstad L, Skovlund E, Fodstad Ø (2004)
    Immunomagnetic detection and clinical significance of micrometastatic tumor cells in malignant melanoma patients
    Clin Cancer Res, 10 (12 Pt 1), 4134-9
    PubMed 15217950
  5. Sundstrøm S, Bremnes R, Aasebø U, Aamdal S, Hatlevoll R, Brunsvig P, Johannessen DC, Klepp O, Fayers PM, Kaasa S (2004)
    Hypofractionated palliative radiotherapy (17 Gy per two fractions) in advanced non-small-cell lung carcinoma is comparable to standard fractionation for symptom control and survival: a national phase III trial
    J Clin Oncol, 22 (5), 801-10
    PubMed 14990635
  6. Sundstrøm S, Bremnes RM, Kaasa S, Aasebø U, Aamdal S, Norwegian Lung Cancer Study Group (2004)
    Second-line chemotherapy in recurrent small cell lung cancer. Results from a crossover schedule after primary treatment with cisplatin and etoposide (EP-regimen) or cyclophosphamide, epirubicin, and vincristin (CEV-regimen)
    Lung Cancer, 48 (2), 251-61
    PubMed 15829326

Publications 2003

  1. Bremnes RM, Sundstrom S, Aasebo U, Kaasa S, Hatlevoll R, Aamdal S, Norwegian Lung Canc Study Grp (2003)
    The value of prognostic factors in small cell lung cancer: results from a randomised multicenter study with minimum 5 year follow-up
    Lung Cancer, 39 (3), PII S0169-5002(02)00508-1-313
  2. Bremnes RM, Sundstrom S, Aasebø U, Kaasa S, Hatlevoll R, Aamdal S, Norweigian Lung Cancer Study Group (2003)
    The value of prognostic factors in small cell lung cancer: results from a randomised multicenter study with minimum 5 year follow-up
    Lung Cancer, 39 (3), 303-13
    PubMed 12609569
  3. Marchand M, Punt CJ, Aamdal S, Escudier B, Kruit WH, Keilholz U, Håkansson L, van Baren N, Humblet Y, Mulders P, Avril MF, Eggermont AM, Scheibenbogen C, Uiters J, Wanders J, Delire M, Boon T, Stoter G (2003)
    Immunisation of metastatic cancer patients with MAGE-3 protein combined with adjuvant SBAS-2: a clinical report
    Eur J Cancer, 39 (1), 70-7
    PubMed 12504661
  4. Marchand M, Punt CJA, Aamdal S, Escudier B, Kruit WHJ, Keilholz U, Hakansson L, van Baren N, Humblet Y, Mulders P, Avril MF, Eggermont AMM, Scheibenbogen C, Uiters J, Wanders J, Delire M, Boon T, Stoter G (2003)
    Immunisation of metastatic cancer patients with MAGE-3 protein combined with adjuvant SBAS-2: a clinical report
    Eur. J. Cancer, 39 (1), PII S0959-8049(02)00479-3-77

Publications 2002

  1. Sundstrøm S, Bremnes RM, Kaasa S, Aasebø U, Hatlevoll R, Dahle R, Boye N, Wang M, Vigander T, Vilsvik J, Skovlund E, Hannisdal E, Aamdal S, Norwegian Lung Cancer Study Group (2002)
    Cisplatin and etoposide regimen is superior to cyclophosphamide, epirubicin, and vincristine regimen in small-cell lung cancer: results from a randomized phase III trial with 5 years' follow-up
    J Clin Oncol, 20 (24), 4665-72
    PubMed 12488411

Publications 2001

  1. Bos AM, de Vries EG, Dombernovsky P, Aamdal S, Uges DR, Schrijvers D, Wanders J, Roelvink MW, Hanauske AR, Bortini S, Capriati A, Crea AE, Vermorken JB (2001)
    Pharmacokinetics of MEN-10755, a novel anthracycline disaccharide analogue, in two phase I studies in adults with advanced solid tumours
    Cancer Chemother Pharmacol, 48 (5), 361-9
    PubMed 11761453
  2. Fodstad O, Faye R, Høifødt HK, Skovlund E, Aamdal S (2001)
    Immunobead-based detection and characterization of circulating tumor cells in melanoma patients
    Recent Results Cancer Res, 158, 40-50
    PubMed 11092032
  3. Hovig E, Myklebost O, Aamdal S, Smeland EB (2001)
    [Gene therapy in cancer]
    Tidsskr Nor Laegeforen, 121 (4), 482-8
    PubMed 11255868
  4. Sudbø J, Warloe T, Aamdal S, Reith A, Bryne M (2001)
    [Diagnosis and treatment of oral precancerous lesions]
    Tidsskr Nor Laegeforen, 121 (26), 3066-71 (Retracted)
    PubMed 11757442

Publications 2000

  1. Middleton MR, Grob JJ, Aaronson N, Fierlbeck G, Tilgen W, Seiter S, Gore M, Aamdal S, Cebon J, Coates A, Dreno B, Henz M, Schadendorf D, Kapp A, Weiss J, Fraass U, Statkevich P, Muller M, Thatcher N (2000)
    Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma
    J Clin Oncol, 18 (1), 158-66
    PubMed 10623706
  2. Pavlidis N, Aamdal S, Awada A, Calvert H, Fumoleau P, Sorio R, Punt C, Verweij J, van Oosterom A, Morant R, Wanders J, Hanauske AR (2000)
    Carzelesin phase II study in advanced breast, ovarian, colorectal, gastric, head and neck cancer, non-Hodgkin's lymphoma and malignant melanoma: a study of the EORTC early clinical studies group (ECSG)
    Cancer Chemother Pharmacol, 46 (2), 167-71
    PubMed 10972487
  3. Aamdal S, Lund B, Koier I, Houten M, Wanders J, Verweij J (2000)
    Phase I trial with weekly EO9, a novel bioreductive alkylating indoloquinone, by the EORTC Early Clinical Study Group (ECSG)
    Cancer Chemother Pharmacol, 45 (1), 85-8
    PubMed 10647507

Publications 1998

  1. Jungnelius U, Ringborg U, Aamdal S, Mattsson J, Stierner U, Ingvar C, Malmström P, Andersson R, Karlsson M, Willman K, Wist E, Bjelkengren G, Westberg R (1998)
    Dacarbazine-vindesine versus dacarbazine-vindesine-cisplatin in disseminated malignant melanoma. A randomised phase III trial
    Eur J Cancer, 34 (9), 1368-74
    PubMed 9849419
  2. Semb KA, Aamdal S, Bohmann T, Lucas C, Gerard B (1998)
    Clinical experience of fotemustine, cisplatin and high dose tamoxifen in patients with metastatic malignant melanoma
    Melanoma Res, 8 (6), 565-72
    PubMed 9918419
  3. Semb KA, Aamdal S, Mette E, Ingvar C, Gullaksen N, Osmundsen K (1998)
    Zilascorb(H-2), a low-toxicity protein synthesis inhibitor that exhibits signs of anticancer activity in malignant melanoma
    Anti-Cancer Drugs, 9 (9), 797-802
  4. Semb KA, Aamdal S, Mette E, Ingvar C, Gullaksen N, Osmundsen K (1998)
    Zilascorb(2H), a low-toxicity protein synthesis inhibitor that exhibits signs of anticancer activity in malignant melanoma
    Anticancer Drugs, 9 (9), 797-802
    PubMed 9840726
  5. Semb KA, Aamdal S, Oian P (1998)
    Capillary protein leak syndrome appears to explain fluid retention in cancer patients who receive docetaxel treatment
    J Clin Oncol, 16 (10), 3426-32
    PubMed 9779722

Publications 1997

  1. Semb KA, Fodstad O, Klem B, Bibow K, Osmundsen K, Aamdal S (1997)
    Zilascorb(H-2), a new reversible protein synthesis inhibitor: Clinical study of an oral preparation
    Anti-Cancer Drugs, 8 (3), 296-303
  2. Semb KA, Fodstad O, Klem B, Bibow K, Osmundsen K, Aamdal S (1997)
    Zilascorb(2H), a new reversible protein synthesis inhibitor: clinical study of an oral preparation
    Anticancer Drugs, 8 (3), 296-303
    PubMed 9095337
  3. Aamdal S, Bruntsch U, Kerger J, Verweij J, ten Bokkel Huinink W, Wanders J, Rastogi R, Franklin HR, Kaye SB (1997)
    Zeniplatin in advanced malignant melanoma and renal cancer: phase II studies with unexpected nephrotoxicity
    Cancer Chemother Pharmacol, 40 (5), 439-43
    PubMed 9272122

Publications 1996

  1. Hanauske AR, Catimel G, Aamdal S, ten Bokkel Huinink W, Paridaens R, Pavlidis N, Kaye SB, te Velde A, Wanders J, Verweij J (1996)
    Phase II clinical trials with rhizoxin in breast cancer and melanoma. The EORTC Early Clinical Trials Group
    Br J Cancer, 73 (3), 397-9
    PubMed 8562349
  2. Karlsson M, Jungnelius U, Aamdal S, Boeryd B, Carstensen J, Kågedal B, Westberg R, Wingren S (1996)
    Correlation of DNA ploidy and S-phase fraction with chemotherapeutic response and survival in a randomized study of disseminated malignant melanoma
    Int J Cancer, 65 (1), 1-5
    PubMed 8543385
  3. McLeod HL, Graham MA, Aamdal S, Setanoians A, Groot Y, Lund B (1996)
    Phase I pharmacokinetics and limited sampling strategies for the bioreductive alkylating drug EO9. EORTC Early Clinical Trials Group
    Eur J Cancer, 32A (9), 1518-22
    PubMed 8911111
  4. McLeod HL, Murray LS, Wanders J, Setanoians A, Graham MA, Pavlidis N, Heinrich B, ten Bokkel Huinink WW, Wagener DJ, Aamdal S, Verweij J (1996)
    Multicentre phase II pharmacological evaluation of rhizoxin. Eortc early clinical studies (ECSG)/pharmacology and molecular mechanisms (PAMM) groups
    Br J Cancer, 74 (12), 1944-8
    PubMed 8980394
  5. Semb KA, Aamdal S, Fosså SD, Oian P (1996)
    Transcapillary forces of the subcutaneous tissue in patients treated with interleukin-2 and alpha-interferon: no capillary protein leak syndrome?
    J Exp Ther Oncol, 1 (3), 155-61
    PubMed 9414399

Publications 1995

  1. Fosså SD, Aamdal S, Naume B, Gallati H (1995)
    Serum levels of cytokines and soluble cytokine receptors in patients with metastatic renal cell carcinoma or malignant melanoma receiving IL-2/interferon-alpha combination therapy
    Acta Oncol, 34 (5), 599-603
    PubMed 7546824
  2. Verweij J, Catimel G, Sulkes A, Sternberg C, Wolff I, Aamdal S, van Hoesel Q (1995)
    Phase II studies of docetaxel in the treatment of various solid tumours. EORTC Early Clinical Trials Group and the EORTC Soft Tissue and Bone Sarcoma Group
    Eur J Cancer, 31A Suppl 4, S21-4
    PubMed 7577101

Publications 1994

  1. Sessa C, Aamdal S, Wolff I, Eppelbaum R, Smyth JF, Sulkes A, Ten Bokkel Huinink W, Vermorken J, Wanders J, Franklin H (1994)
    Gemcitabine in patients with advanced malignant melanoma or gastric cancer: phase II studies of the EORTC Early Clinical Trials Group
    Ann Oncol, 5 (5), 471-2
    PubMed 8075055
  2. Verweij J, Aamdal S, Schellens J, Koier I, Lund B (1994)
    Clinical studies with EO9, a new indoloquinone bioreductive alkylating cytotoxic agent. EORTC Early Clinical Trials Group
    Oncol Res, 6 (10-11), 519-23
    PubMed 7620220
  3. Aamdal S, Wolff I, Kaplan S, Paridaens R, Kerger J, Schachter J, Wanders J, Franklin HR, Verweij J (1994)
    Docetaxel (Taxotere) in advanced malignant melanoma: a phase II study of the EORTC Early Clinical Trials Group
    Eur J Cancer, 30A (8), 1061-4
    PubMed 7654429

Publications 1993

  1. Gerard B, Aamdal S, Lee SM, Leyvraz S, Lucas C, D'Incalci M, Bizzari JP (1993)
    Activity and unexpected lung toxicity of the sequential administration of two alkylating agents--dacarbazine and fotemustine--in patients with melanoma
    Eur J Cancer, 29A (5), 711-9
    PubMed 8471329
  2. Lundby B, Berg KJ, Lien HH, Aamdal S (1993)
    A double blind study to evaluate the tolerability of gadodiamide injection and its effect on renal function in patients undergoing cerebral magnetic resonance imaging
    Br J Radiol, 66 (790), 871-6
    PubMed 8220968

Publications 1992

  1. Beiske K, Myklebust AT, Aamdal S, Langholm R, Jakobsen E, Fodstad O (1992)
    Detection of bone marrow metastases in small cell lung cancer patients. Comparison of immunologic and morphologic methods
    Am J Pathol, 141 (3), 531-8
    PubMed 1381558
  2. Flørenes VA, Aamdal S, Myklebost O, Maelandsmo GM, Bruland OS, Fodstad O (1992)
    Levels of nm23 messenger RNA in metastatic malignant melanomas: inverse correlation to disease progression
    Cancer Res, 52 (21), 6088-91
    PubMed 1356624
  3. Wibe E, Hannisdal E, Paus E, Aamdal S (1992)
    Neuron-specific enolase as a prognostic factor in metastatic malignant melanoma
    Eur J Cancer, 28A (10), 1692-5
    PubMed 1389487
  4. Aamdal S (1992)
    Can ondansetron hydrochloride (Zofran) enhance the nephrotoxic potential of other drugs?
    Ann Oncol, 3 (9), 774
    PubMed 1450070
  5. Aamdal S, Gerard B, Bohman T, D'Incalci M (1992)
    Sequential administration of dacarbazine and fotemustine in patients with disseminated malignant melanoma--an effective combination with unexpected toxicity
    Eur J Cancer, 28 (2-3), 447-50
    PubMed 1591062

Publications 1991

  1. Myklebust AT, Beiske K, Pharo A, Davies CD, Aamdal S, Fodstad O (1991)
    Selection of anti-SCLC antibodies for diagnosis of bone marrow metastasis
    Br J Cancer Suppl, 14, 49-53
    PubMed 1645572
  2. Stoter G, Aamdal S, Rodenhuis S, Cleton FJ, Iacobelli S, Franks CR, Oskam R, Shiloni E (1991)
    Sequential administration of recombinant human interleukin-2 and dacarbazine in metastatic melanoma: a multicenter phase II study
    J Clin Oncol, 9 (9), 1687-91
    PubMed 1875225

Publications 1990

  1. Tefre T, Børresen AL, Aamdal S, Brøgger A (1990)
    Studies of the L-myc DNA polymorphism and relation to metastasis in Norwegian lung cancer patients
    Br J Cancer, 61 (6), 809-12
    PubMed 1973618
  2. Wibe E, Paus E, Aamdal S (1990)
    Neuron specific enolase (NSE) in serum of patients with malignant melanoma
    Cancer Lett, 52 (1), 29-31
    PubMed 2354416

Publications 1989

  1. Stoter G, Shiloni E, Aamdal S, Cleton FJ, Iacobelli S, Bijman JT, Palmer P, Franks CR, Rodenhuis S (1989)
    Sequential administration of recombinant human interleukin-2 and dacarbazine in metastatic melanoma. A multicentre phase II study
    Eur J Cancer Clin Oncol, 25 Suppl 3, S41-3
    PubMed 2697578

Publications 1988

  1. Fodstad O, Kjønniksen I, Aamdal S, Nesland JM, Boyd MR, Pihl A (1988)
    Extrapulmonary, tissue-specific metastasis formation in nude mice injected with FEMX-I human melanoma cells
    Cancer Res, 48 (15), 4382-8
    PubMed 3390834
  2. Fodstad O, Aamdal S, McMenamin M, Nesland JM, Pihl A (1988)
    A new experimental metastasis model in athymic nude mice, the human malignant melanoma LOX
    Int J Cancer, 41 (3), 442-9
    PubMed 3346110
  3. Aamdal S, Fodstad O, Pihl A (1988)
    Sodium thiosulfate fails to increase the therapeutic index of intravenously administered cis-diamminedichloroplatinum (II) in mice bearing murine and human tumors
    Cancer Chemother Pharmacol, 21 (2), 129-33
    PubMed 3349560

Publications 1987

  1. Gundersen S, Aamdal S, Fodstad O (1987)
    Mitozolomide (NSC 353451), a new active drug in the treatment of malignant melanoma. Phase II trial in patients with advanced disease
    Br J Cancer, 55 (4), 433-5
    PubMed 3580266
  2. Aamdal S, Fodstad O, Pihl A (1987)
    Some procedures to reduce cis-platinum toxicity reduce antitumour activity
    Cancer Treat Rev, 14 (3-4), 389-95
    PubMed 3326670

Publications 1986

  1. Aamdal S, Fodstad O, Kaalhus O, Pihl A (1986)
    Chemosensitivity profiles of human cancers assessed by the 6-day SRC assay on serially xenografted tumors
    Int J Cancer, 37 (4), 579-87
    PubMed 3957463

Publications 1985

  1. Fodstad O, Aamdal S, Pihl A, Boyd MR (1985)
    Activity of mitozolomide (NSC 353451), a new imidazotetrazine, against xenografts from human melanomas, sarcomas, and lung and colon carcinomas
    Cancer Res, 45 (4), 1778-86
    PubMed 3978640
  2. Aamdal S, Fodstad O, Nesland JM, Pihl A (1985)
    Characteristics of human tumour xenografts transplanted under the renal capsule of immunocompetent mice
    Br J Cancer, 51 (3), 347-56
    PubMed 3970811
  3. Aamdal S, Fodstad O, Pihl A (1985)
    The six-day subrenal capsule assay (SRCA) for testing the response of human tumours to anticancer agents. Validity and usefulness in cancer research and treatment
    Ann Chir Gynaecol Suppl, 199, 51-9
    PubMed 3864392
  4. Aamdal S, Fodstad O, Pihl A (1985)
    Methodological aspects of the 6-day subrenal capsule assay for measuring the response of human tumors to anticancer agents
    Anticancer Res, 5 (4), 329-37
    PubMed 4037730

Publications 1984

  1. Fodstad O, Kvalheim G, Godal A, Lotsberg J, Aamdal S, Høst H, Pihl A (1984)
    Phase I study of the plant protein ricin
    Cancer Res, 44 (2), 862-5
    PubMed 6692385
  2. Aamdal S, Børmer O, Jørgensen O, Høst H, Eliassen G, Kaalhus O, Pihl A (1984)
    Estrogen receptors and long-term prognosis in breast cancer
    Cancer, 53 (11), 2525-9
    PubMed 6713348
  3. Aamdal S, Fodstad O, Kaalhus O, Pihl A (1984)
    Reduced antineoplastic activity in mice of cisplatin administered with high salt concentration in the vehicle
    J Natl Cancer Inst, 73 (3), 743-52
    PubMed 6590919
  4. Aamdal S, Fodstad O, Pihl A (1984)
    Human tumor xenografts transplanted under the renal capsule of conventional mice. Growth rates and host immune response
    Int J Cancer, 34 (5), 725-30
    PubMed 6500747
 

Author network for Steinar Aamdal by COREMINE medical


Publications 2016

Kyte JA, Gaudernack G, Faane A, Lislerud K, Inderberg EM, Brunsvig P, Aamdal S, Kvalheim G, Wälchli S, Pule M (2016)
T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy
Oncoimmunology, 5 (12), e1249090
PubMed 28123886

Kyte JA, Aamdal S, Dueland S, Sæbøe-Larsen S, Inderberg EM, Madsbu UE, Skovlund E, Gaudernack G, Kvalheim G (2016)
Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells
Oncoimmunology, 5 (11), e1232237
PubMed 27999747

Sioud M, Nyakas M, Sæbøe-Larssen S, Mobergslien A, Aamdal S, Kvalheim G (2016)
Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine
Case Rep Med, 2016, 9639585
PubMed 27504122

Publications 2015

Andersson Y, Engebraaten O, Juell S, Aamdal S, Brunsvig P, Fodstad Ø, Dueland S (2015)
Phase I trial of EpCAM-targeting immunotoxin MOC31PE, alone and in combination with cyclosporin
Br J Cancer, 113 (11), 1548-55
PubMed 26554649

Maio M, Grob JJ, Aamdal S, Bondarenko I, Robert C, Thomas L, Garbe C, Chiarion-Sileni V, Testori A, Chen TT, Tschaika M, Wolchok JD (2015)
Five-year survival rates for treatment-naive patients with advanced melanoma who received ipilimumab plus dacarbazine in a phase III trial
J Clin Oncol, 33 (10), 1191-6
PubMed 25713437

Prasmickaite L, Berge G, Bettum IJ, Aamdal S, Hansson J, Bastholt L, Øijordsbakken M, Boye K, Mælandsmo GM (2015)
Evaluation of serum osteopontin level and gene polymorphism as biomarkers: analyses from the Nordic Adjuvant Interferon alpha Melanoma trial
Cancer Immunol Immunother, 64 (6), 769-76
PubMed 25832001

Venugopal B, Awada A, Evans TR, Dueland S, Hendlisz A, Rasch W, Hernes K, Hagen S, Aamdal S (2015)
A first-in-human phase I and pharmacokinetic study of CP-4126 (CO-101), a nucleoside analogue, in patients with advanced solid tumours
Cancer Chemother Pharmacol, 76 (4), 785-92
PubMed 26289594

Publications 2014

Vihinen P, Tervahartiala T, Sorsa T, Hansson J, Bastholt L, Aamdal S, Stierner U, Pyrhönen S, Syrjänen K, Lundin J, Hernberg M (2014)
Benefit of adjuvant interferon alfa-2b (IFN-α) therapy in melanoma patients with high serum MMP-8 levels
Cancer Immunol Immunother, 64 (2), 173-80
PubMed 25319807

Publications 2013

Brandberg Y, Johansson H, Aamdal S, Bastholt L, Hernberg M, Stierner U, von der Maase H, Hansson J, Nordic Melanoma Cooperative Group (2013)
Role functioning before start of adjuvant treatment was an independent prognostic factor for survival and time to failure. A report from the Nordic adjuvant interferon trial for patients with high-risk melanoma
Acta Oncol, 52 (6), 1086-93
PubMed 23621752

Cohen RB, Aamdal S, Nyakas M, Cavallin M, Green D, Learoyd M, Smith I, Kurzrock R (2013)
A phase I dose-finding, safety and tolerability study of AZD8330 in patients with advanced malignancies
Eur J Cancer, 49 (7), 1521-9
PubMed 23433846

del Campo AB, Kyte JA, Carretero J, Zinchencko S, Méndez R, González-Aseguinolaza G, Ruiz-Cabello F, Aamdal S, Gaudernack G, Garrido F, Aptsiauri N (2013)
Immune escape of cancer cells with beta2-microglobulin loss over the course of metastatic melanoma
Int J Cancer, 134 (1), 102-13
PubMed 23784959

Eggermont AM, Suciu S, Rutkowski P, Marsden J, Santinami M, Corrie P, Aamdal S, Ascierto PA, Patel PM, Kruit WH, Bastholt L, Borgognoni L, Bernengo MG, Davidson N, Polders L, Praet M, Spatz A (2013)
Adjuvant ganglioside GM2-KLH/QS-21 vaccination versus observation after resection of primary tumor > 1.5 mm in patients with stage II melanoma: results of the EORTC 18961 randomized phase III trial
J Clin Oncol, 31 (30), 3831-7
PubMed 24019551

Geisler J, Bachmann IM, Nyakas M, Helsing P, Fjøsne HE, Mæhle LO, Aamdal S, Eide NA, Svendsen HL, Straume O, Robsahm TE, Jacobsen KD, Akslen LA (2013)
Malignant melanoma--diagnosis, treatment and follow-up in Norway
Tidsskr Nor Laegeforen, 133 (20), 2154-9
PubMed 24172628

Vik-Mo EO, Nyakas M, Mikkelsen BV, Moe MC, Due-Tønnesen P, Suso EM, Sæbøe-Larssen S, Sandberg C, Brinchmann JE, Helseth E, Rasmussen AM, Lote K, Aamdal S, Gaudernack G, Kvalheim G, Langmoen IA (2013)
Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma
Cancer Immunol Immunother, 62 (9), 1499-509
PubMed 23817721

Publications 2012

Kaye S, Aamdal S, Jones R, Freyer G, Pujade-Lauraine E, de Vries EG, Barriuso J, Sandhu S, Tan DS, Hartog V, Kuenen B, Ruijter R, Kristensen GB, Nyakas M, Barrett S, Burke W, Pietersma D, Stuart M, Emeribe U, Boven E (2012)
Phase I study of saracatinib (AZD0530) in combination with paclitaxel and/or carboplatin in patients with solid tumours
Br J Cancer, 106 (11), 1728-34
PubMed 22531637

Publications 2011

Brandberg Y, Aamdal S, Bastholt L, Hernberg M, Stierner U, von der Maase H, Hansson J (2011)
Health-related quality of life in patients with high-risk melanoma randomised in the Nordic phase 3 trial with adjuvant intermediate-dose interferon alfa-2b
Eur J Cancer, 48 (13), 2012-9
PubMed 22196968

Brunsvig PF, Kyte JA, Kersten C, Sundstrøm S, Møller M, Nyakas M, Hansen GL, Gaudernack G, Aamdal S (2011)
Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial
Clin Cancer Res, 17 (21), 6847-57
PubMed 21918169

Fox BA, Schendel DJ, Butterfield LH, Aamdal S, Allison JP, Ascierto PA, Atkins MB, Bartunkova J, Bergmann L, Berinstein N, Bonorino CC, Borden E, Bramson JL, Britten CM, Cao X, Carson WE, Chang AE, Characiejus D, Choudhury AR, Coukos G, de Gruijl T, Dillman RO, Dolstra H, Dranoff G, Durrant LG et al. (2011)
Defining the critical hurdles in cancer immunotherapy
J Transl Med, 9, 214
PubMed 22168571

Hamid O, Schmidt H, Nissan A, Ridolfi L, Aamdal S, Hansson J, Guida M, Hyams DM, Gómez H, Bastholt L, Chasalow SD, Berman D (2011)
A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma
J Transl Med, 9, 204
PubMed 22123319

Hansson J, Aamdal S, Bastholt L, Brandberg Y, Hernberg M, Nilsson B, Stierner U, von der Maase H, Nordic Melanoma Cooperative Group (2011)
Two different durations of adjuvant therapy with intermediate-dose interferon alfa-2b in patients with high-risk melanoma (Nordic IFN trial): a randomised phase 3 trial
Lancet Oncol, 12 (2), 144-52
PubMed 21256809

Kyte JA, Gaudernack G, Dueland S, Trachsel S, Julsrud L, Aamdal S (2011)
Telomerase peptide vaccination combined with temozolomide: a clinical trial in stage IV melanoma patients
Clin Cancer Res, 17 (13), 4568-80
PubMed 21586625

Suso EM, Dueland S, Rasmussen AM, Vetrhus T, Aamdal S, Kvalheim G, Gaudernack G (2011)
hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
Cancer Immunol Immunother, 60 (6), 809-18
PubMed 21365467

Zwierzina H, Bergmann L, Fiebig H, Aamdal S, Schöffski P, Witthohn K, Lentzen H (2011)
The preclinical and clinical activity of aviscumine: a potential anticancer drug
Eur J Cancer, 47 (10), 1450-7
PubMed 21482461

Aamdal S (2011)
Current approaches to adjuvant therapy of melanoma
Eur J Cancer, 47 Suppl 3, S336-7
PubMed 21944005

Publications 2010

Edvardsen H, Brunsvig PF, Solvang H, Tsalenko A, Andersen A, Syvanen AC, Yakhini Z, Børresen-Dale AL, Olsen H, Aamdal S, Kristensen VN (2010)
SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance
Pharmacogenomics J, 10 (6), 513-23
PubMed 20157331

Prasmickaite L, Skrbo N, Høifødt HK, Suo Z, Engebråten O, Gullestad HP, Aamdal S, Fodstad Ø, Maelandsmo GM (2010)
Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells
Pigment Cell Melanoma Res, 23 (3), 449-51
PubMed 20236249

Publications 2009

Bouwhuis MG, Suciu S, Collette S, Aamdal S, Kruit WH, Bastholt L, Stierner U, Salès F, Patel P, Punt CJ, Hernberg M, Spatz A, ten Hagen TL, Hansson J, Eggermont AM, EORTC Melanoma Group and the Nordic Melanoma Group (2009)
Autoimmune antibodies and recurrence-free interval in melanoma patients treated with adjuvant interferon
J Natl Cancer Inst, 101 (12), 869-77
PubMed 19509353

Dueland S, Aamdal S, Lind MJ, Thomas H, Sandvold ML, Gaullier JM, Rasch W (2009)
Intravenous administration of CP-4055 (ELACYT) in patients with solid tumours. A Phase I study
Acta Oncol, 48 (1), 137-45
PubMed 18607882

Gunnes N, Seierstad TG, Aamdal S, Brunsvig PF, Jacobsen AB, Sundstrøm S, Aalen OO (2009)
Assessing quality of life in a randomized clinical trial: correcting for missing data
BMC Med Res Methodol, 9, 28
PubMed 19405936

Publications 2008

Brunsvig PF, Flatmark K, Aamdal S, Høifødt H, Le H, Jakobsen E, Sandstad B, Fodstad O (2008)
Bone marrow micrometastases in advanced stage non-small cell lung carcinoma patients
Lung Cancer, 61 (2), 170-6
PubMed 18261824

Faye RS, Paus E, Maelandsmo GM, Berner A, Høifødt HK, Fodstad Ø, Aamdal S (2008)
S100B in bone marrow aspirates in healthy individuals and malignant melanoma patients
Melanoma Res, 18 (2), 134-40
PubMed 18337650

Helsing P, Nymoen DA, Ariansen S, Steine SJ, Maehle L, Aamdal S, Langmark F, Loeb M, Akslen LA, Molven A, Andresen PA (2008)
Population-based prevalence of CDKN2A and CDK4 mutations in patients with multiple primary melanomas
Genes Chromosomes Cancer, 47 (2), 175-84
PubMed 18023021

Publications 2007

Brunsvig PF, Andersen A, Aamdal S, Kristensen V, Olsen H (2007)
Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy
BMC Cancer, 7, 197
PubMed 17956601

Hernberg M, Mattila PS, Rissanen M, Hansson J, Aamdal S, Bastholt L, von der Maase H, Schmidt H, Stierner U, Tarkkanen J (2007)
The prognostic role of blood lymphocyte subset distribution in patients with resected high-risk primary or regionally metastatic melanoma
J Immunother, 30 (7), 773-9
PubMed 17893569

Publications 2006

Andersen A, Warren DJ, Brunsvig PF, Aamdal S, Kristensen GB, Olsen H (2006)
High sensitivity assays for docetaxel and paclitaxel in plasma using solid-phase extraction and high-performance liquid chromatography with UV detection
BMC Clin Pharmacol, 6, 2
PubMed 16412237

Brunsvig PF, Aamdal S, Gjertsen MK, Kvalheim G, Markowski-Grimsrud CJ, Sve I, Dyrhaug M, Trachsel S, Møller M, Eriksen JA, Gaudernack G (2006)
Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
Cancer Immunol Immunother, 55 (12), 1553-64
PubMed 16491401

Jacobsen KD, Fosså SD, Aamdal S (2006)
[Malignant melanoma--diagnosis and treatment]
Tidsskr Nor Laegeforen, 126 (23), 3094-7
PubMed 17160112

Kyte JA, Kvalheim G, Lislerud K, thor Straten P, Dueland S, Aamdal S, Gaudernack G (2006)
T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
Cancer Immunol Immunother, 56 (5), 659-75
PubMed 16947019

Kyte JA, Mu L, Aamdal S, Kvalheim G, Dueland S, Hauser M, Gullestad HP, Ryder T, Lislerud K, Hammerstad H, Gaudernack G (2006)
Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
Cancer Gene Ther, 13 (10), 905-18
PubMed 16710345

Warloe T, Aamdal S, Reith A, Bryne M (2006)
[Retraction of: Diagnostics and treatment of early stages of oral cancer]
Tidsskr Nor Laegeforen, 126 (17), 2287
PubMed 16967079

Publications 2005

Brunsvig PF, Hatlevoll R, Berg R, Lauvvang G, Owre K, Wang M, Aamdal S (2005)
Weekly docetaxel with concurrent radiotherapy in locally advanced non-small cell lung cancer: a phase I/II study with 5 years' follow-up
Lung Cancer, 50 (1), 97-105
PubMed 16005105

Kyte JA, Kvalheim G, Aamdal S, Saebøe-Larssen S, Gaudernack G (2005)
Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
Cancer Gene Ther, 12 (6), 579-91
PubMed 15818380

Millward MJ, Joshua A, Kefford R, Aamdal S, Thomson D, Hersey P, Toner G, Lynch K (2005)
Multi-centre Phase II trial of the polyamine synthesis inhibitor SAM486A (CGP48664) in patients with metastatic melanoma
Invest New Drugs, 23 (3), 253-6
PubMed 15868382

Mu LJ, Kyte JA, Kvalheim G, Aamdal S, Dueland S, Hauser M, Hammerstad H, Waehre H, Raabe N, Gaudernack G (2005)
Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
Br J Cancer, 93 (7), 749-56
PubMed 16136047

Smyth JF, Aamdal S, Awada A, Dittrich C, Caponigro F, Schöffski P, Gore M, Lesimple T, Djurasinovic N, Baron B, Ravic M, Fumoleau P, Punt CJ, EORTC New Drug Development and Melanoma Groups (2005)
Phase II study of E7070 in patients with metastatic melanoma
Ann Oncol, 16 (1), 158-61
PubMed 15598954

Publications 2004

Avril MF, Aamdal S, Grob JJ, Hauschild A, Mohr P, Bonerandi JJ, Weichenthal M, Neuber K, Bieber T, Gilde K, Guillem Porta V, Fra J, Bonneterre J, Saïag P, Kamanabrou D, Pehamberger H, Sufliarsky J, Gonzalez Larriba JL, Scherrer A, Menu Y (2004)
Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study
J Clin Oncol, 22 (6), 1118-25
PubMed 15020614

Bos AM, Boom K, Vinks AA, Boezen HM, Wanders J, Dombernovsky P, Aamdal S, de Vries EG, Uges DR (2004)
Development of an optimal sampling strategy for clinical pharmacokinetic studies of the novel anthracycline disaccharide analogue MEN-10755
Cancer Chemother Pharmacol, 54 (1), 64-70
PubMed 15069581

Cheng JD, Babb JS, Langer C, Aamdal S, Robert F, Engelhardt LR, Fernberg O, Schiller J, Forsberg G, Alpaugh RK, Weiner LM, Rogatko A (2004)
Individualized patient dosing in phase I clinical trials: the role of escalation with overdose control in PNU-214936
J Clin Oncol, 22 (4), 602-9
PubMed 14966084

Faye RS, Aamdal S, Høifødt HK, Jacobsen E, Holstad L, Skovlund E, Fodstad Ø (2004)
Immunomagnetic detection and clinical significance of micrometastatic tumor cells in malignant melanoma patients
Clin Cancer Res, 10 (12 Pt 1), 4134-9
PubMed 15217950

Sundstrøm S, Bremnes R, Aasebø U, Aamdal S, Hatlevoll R, Brunsvig P, Johannessen DC, Klepp O, Fayers PM, Kaasa S (2004)
Hypofractionated palliative radiotherapy (17 Gy per two fractions) in advanced non-small-cell lung carcinoma is comparable to standard fractionation for symptom control and survival: a national phase III trial
J Clin Oncol, 22 (5), 801-10
PubMed 14990635

Sundstrøm S, Bremnes RM, Kaasa S, Aasebø U, Aamdal S, Norwegian Lung Cancer Study Group (2004)
Second-line chemotherapy in recurrent small cell lung cancer. Results from a crossover schedule after primary treatment with cisplatin and etoposide (EP-regimen) or cyclophosphamide, epirubicin, and vincristin (CEV-regimen)
Lung Cancer, 48 (2), 251-61
PubMed 15829326

Publications 2003

Bremnes RM, Sundstrom S, Aasebo U, Kaasa S, Hatlevoll R, Aamdal S, Norwegian Lung Canc Study Grp (2003)
The value of prognostic factors in small cell lung cancer: results from a randomised multicenter study with minimum 5 year follow-up
Lung Cancer, 39 (3), PII S0169-5002(02)00508-1-313

Bremnes RM, Sundstrom S, Aasebø U, Kaasa S, Hatlevoll R, Aamdal S, Norweigian Lung Cancer Study Group (2003)
The value of prognostic factors in small cell lung cancer: results from a randomised multicenter study with minimum 5 year follow-up
Lung Cancer, 39 (3), 303-13
PubMed 12609569

Marchand M, Punt CJ, Aamdal S, Escudier B, Kruit WH, Keilholz U, Håkansson L, van Baren N, Humblet Y, Mulders P, Avril MF, Eggermont AM, Scheibenbogen C, Uiters J, Wanders J, Delire M, Boon T, Stoter G (2003)
Immunisation of metastatic cancer patients with MAGE-3 protein combined with adjuvant SBAS-2: a clinical report
Eur J Cancer, 39 (1), 70-7
PubMed 12504661

Marchand M, Punt CJA, Aamdal S, Escudier B, Kruit WHJ, Keilholz U, Hakansson L, van Baren N, Humblet Y, Mulders P, Avril MF, Eggermont AMM, Scheibenbogen C, Uiters J, Wanders J, Delire M, Boon T, Stoter G (2003)
Immunisation of metastatic cancer patients with MAGE-3 protein combined with adjuvant SBAS-2: a clinical report
Eur. J. Cancer, 39 (1), PII S0959-8049(02)00479-3-77

Publications 2002

Sundstrøm S, Bremnes RM, Kaasa S, Aasebø U, Hatlevoll R, Dahle R, Boye N, Wang M, Vigander T, Vilsvik J, Skovlund E, Hannisdal E, Aamdal S, Norwegian Lung Cancer Study Group (2002)
Cisplatin and etoposide regimen is superior to cyclophosphamide, epirubicin, and vincristine regimen in small-cell lung cancer: results from a randomized phase III trial with 5 years' follow-up
J Clin Oncol, 20 (24), 4665-72
PubMed 12488411

Publications 2001

Bos AM, de Vries EG, Dombernovsky P, Aamdal S, Uges DR, Schrijvers D, Wanders J, Roelvink MW, Hanauske AR, Bortini S, Capriati A, Crea AE, Vermorken JB (2001)
Pharmacokinetics of MEN-10755, a novel anthracycline disaccharide analogue, in two phase I studies in adults with advanced solid tumours
Cancer Chemother Pharmacol, 48 (5), 361-9
PubMed 11761453

Fodstad O, Faye R, Høifødt HK, Skovlund E, Aamdal S (2001)
Immunobead-based detection and characterization of circulating tumor cells in melanoma patients
Recent Results Cancer Res, 158, 40-50
PubMed 11092032

Hovig E, Myklebost O, Aamdal S, Smeland EB (2001)
[Gene therapy in cancer]
Tidsskr Nor Laegeforen, 121 (4), 482-8
PubMed 11255868

Sudbø J, Warloe T, Aamdal S, Reith A, Bryne M (2001)
[Diagnosis and treatment of oral precancerous lesions]
Tidsskr Nor Laegeforen, 121 (26), 3066-71 (Retracted)
PubMed 11757442

Publications 2000

Middleton MR, Grob JJ, Aaronson N, Fierlbeck G, Tilgen W, Seiter S, Gore M, Aamdal S, Cebon J, Coates A, Dreno B, Henz M, Schadendorf D, Kapp A, Weiss J, Fraass U, Statkevich P, Muller M, Thatcher N (2000)
Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma
J Clin Oncol, 18 (1), 158-66
PubMed 10623706

Pavlidis N, Aamdal S, Awada A, Calvert H, Fumoleau P, Sorio R, Punt C, Verweij J, van Oosterom A, Morant R, Wanders J, Hanauske AR (2000)
Carzelesin phase II study in advanced breast, ovarian, colorectal, gastric, head and neck cancer, non-Hodgkin's lymphoma and malignant melanoma: a study of the EORTC early clinical studies group (ECSG)
Cancer Chemother Pharmacol, 46 (2), 167-71
PubMed 10972487

Aamdal S, Lund B, Koier I, Houten M, Wanders J, Verweij J (2000)
Phase I trial with weekly EO9, a novel bioreductive alkylating indoloquinone, by the EORTC Early Clinical Study Group (ECSG)
Cancer Chemother Pharmacol, 45 (1), 85-8
PubMed 10647507

Publications 1998

Jungnelius U, Ringborg U, Aamdal S, Mattsson J, Stierner U, Ingvar C, Malmström P, Andersson R, Karlsson M, Willman K, Wist E, Bjelkengren G, Westberg R (1998)
Dacarbazine-vindesine versus dacarbazine-vindesine-cisplatin in disseminated malignant melanoma. A randomised phase III trial
Eur J Cancer, 34 (9), 1368-74
PubMed 9849419

Semb KA, Aamdal S, Bohmann T, Lucas C, Gerard B (1998)
Clinical experience of fotemustine, cisplatin and high dose tamoxifen in patients with metastatic malignant melanoma
Melanoma Res, 8 (6), 565-72
PubMed 9918419

Semb KA, Aamdal S, Mette E, Ingvar C, Gullaksen N, Osmundsen K (1998)
Zilascorb(H-2), a low-toxicity protein synthesis inhibitor that exhibits signs of anticancer activity in malignant melanoma
Anti-Cancer Drugs, 9 (9), 797-802

Semb KA, Aamdal S, Mette E, Ingvar C, Gullaksen N, Osmundsen K (1998)
Zilascorb(2H), a low-toxicity protein synthesis inhibitor that exhibits signs of anticancer activity in malignant melanoma
Anticancer Drugs, 9 (9), 797-802
PubMed 9840726

Semb KA, Aamdal S, Oian P (1998)
Capillary protein leak syndrome appears to explain fluid retention in cancer patients who receive docetaxel treatment
J Clin Oncol, 16 (10), 3426-32
PubMed 9779722

Publications 1997

Semb KA, Fodstad O, Klem B, Bibow K, Osmundsen K, Aamdal S (1997)
Zilascorb(H-2), a new reversible protein synthesis inhibitor: Clinical study of an oral preparation
Anti-Cancer Drugs, 8 (3), 296-303

Semb KA, Fodstad O, Klem B, Bibow K, Osmundsen K, Aamdal S (1997)
Zilascorb(2H), a new reversible protein synthesis inhibitor: clinical study of an oral preparation
Anticancer Drugs, 8 (3), 296-303
PubMed 9095337

Aamdal S, Bruntsch U, Kerger J, Verweij J, ten Bokkel Huinink W, Wanders J, Rastogi R, Franklin HR, Kaye SB (1997)
Zeniplatin in advanced malignant melanoma and renal cancer: phase II studies with unexpected nephrotoxicity
Cancer Chemother Pharmacol, 40 (5), 439-43
PubMed 9272122

Publications 1996

Hanauske AR, Catimel G, Aamdal S, ten Bokkel Huinink W, Paridaens R, Pavlidis N, Kaye SB, te Velde A, Wanders J, Verweij J (1996)
Phase II clinical trials with rhizoxin in breast cancer and melanoma. The EORTC Early Clinical Trials Group
Br J Cancer, 73 (3), 397-9
PubMed 8562349

Karlsson M, Jungnelius U, Aamdal S, Boeryd B, Carstensen J, Kågedal B, Westberg R, Wingren S (1996)
Correlation of DNA ploidy and S-phase fraction with chemotherapeutic response and survival in a randomized study of disseminated malignant melanoma
Int J Cancer, 65 (1), 1-5
PubMed 8543385

McLeod HL, Graham MA, Aamdal S, Setanoians A, Groot Y, Lund B (1996)
Phase I pharmacokinetics and limited sampling strategies for the bioreductive alkylating drug EO9. EORTC Early Clinical Trials Group
Eur J Cancer, 32A (9), 1518-22
PubMed 8911111

McLeod HL, Murray LS, Wanders J, Setanoians A, Graham MA, Pavlidis N, Heinrich B, ten Bokkel Huinink WW, Wagener DJ, Aamdal S, Verweij J (1996)
Multicentre phase II pharmacological evaluation of rhizoxin. Eortc early clinical studies (ECSG)/pharmacology and molecular mechanisms (PAMM) groups
Br J Cancer, 74 (12), 1944-8
PubMed 8980394

Semb KA, Aamdal S, Fosså SD, Oian P (1996)
Transcapillary forces of the subcutaneous tissue in patients treated with interleukin-2 and alpha-interferon: no capillary protein leak syndrome?
J Exp Ther Oncol, 1 (3), 155-61
PubMed 9414399

Publications 1995

Fosså SD, Aamdal S, Naume B, Gallati H (1995)
Serum levels of cytokines and soluble cytokine receptors in patients with metastatic renal cell carcinoma or malignant melanoma receiving IL-2/interferon-alpha combination therapy
Acta Oncol, 34 (5), 599-603
PubMed 7546824

Verweij J, Catimel G, Sulkes A, Sternberg C, Wolff I, Aamdal S, van Hoesel Q (1995)
Phase II studies of docetaxel in the treatment of various solid tumours. EORTC Early Clinical Trials Group and the EORTC Soft Tissue and Bone Sarcoma Group
Eur J Cancer, 31A Suppl 4, S21-4
PubMed 7577101

Publications 1994

Sessa C, Aamdal S, Wolff I, Eppelbaum R, Smyth JF, Sulkes A, Ten Bokkel Huinink W, Vermorken J, Wanders J, Franklin H (1994)
Gemcitabine in patients with advanced malignant melanoma or gastric cancer: phase II studies of the EORTC Early Clinical Trials Group
Ann Oncol, 5 (5), 471-2
PubMed 8075055

Verweij J, Aamdal S, Schellens J, Koier I, Lund B (1994)
Clinical studies with EO9, a new indoloquinone bioreductive alkylating cytotoxic agent. EORTC Early Clinical Trials Group
Oncol Res, 6 (10-11), 519-23
PubMed 7620220

Aamdal S, Wolff I, Kaplan S, Paridaens R, Kerger J, Schachter J, Wanders J, Franklin HR, Verweij J (1994)
Docetaxel (Taxotere) in advanced malignant melanoma: a phase II study of the EORTC Early Clinical Trials Group
Eur J Cancer, 30A (8), 1061-4
PubMed 7654429

Publications 1993

Gerard B, Aamdal S, Lee SM, Leyvraz S, Lucas C, D'Incalci M, Bizzari JP (1993)
Activity and unexpected lung toxicity of the sequential administration of two alkylating agents--dacarbazine and fotemustine--in patients with melanoma
Eur J Cancer, 29A (5), 711-9
PubMed 8471329

Lundby B, Berg KJ, Lien HH, Aamdal S (1993)
A double blind study to evaluate the tolerability of gadodiamide injection and its effect on renal function in patients undergoing cerebral magnetic resonance imaging
Br J Radiol, 66 (790), 871-6
PubMed 8220968

Publications 1992

Beiske K, Myklebust AT, Aamdal S, Langholm R, Jakobsen E, Fodstad O (1992)
Detection of bone marrow metastases in small cell lung cancer patients. Comparison of immunologic and morphologic methods
Am J Pathol, 141 (3), 531-8
PubMed 1381558

Flørenes VA, Aamdal S, Myklebost O, Maelandsmo GM, Bruland OS, Fodstad O (1992)
Levels of nm23 messenger RNA in metastatic malignant melanomas: inverse correlation to disease progression
Cancer Res, 52 (21), 6088-91
PubMed 1356624

Wibe E, Hannisdal E, Paus E, Aamdal S (1992)
Neuron-specific enolase as a prognostic factor in metastatic malignant melanoma
Eur J Cancer, 28A (10), 1692-5
PubMed 1389487

Aamdal S (1992)
Can ondansetron hydrochloride (Zofran) enhance the nephrotoxic potential of other drugs?
Ann Oncol, 3 (9), 774
PubMed 1450070

Aamdal S, Gerard B, Bohman T, D'Incalci M (1992)
Sequential administration of dacarbazine and fotemustine in patients with disseminated malignant melanoma--an effective combination with unexpected toxicity
Eur J Cancer, 28 (2-3), 447-50
PubMed 1591062

Publications 1991

Myklebust AT, Beiske K, Pharo A, Davies CD, Aamdal S, Fodstad O (1991)
Selection of anti-SCLC antibodies for diagnosis of bone marrow metastasis
Br J Cancer Suppl, 14, 49-53
PubMed 1645572

Stoter G, Aamdal S, Rodenhuis S, Cleton FJ, Iacobelli S, Franks CR, Oskam R, Shiloni E (1991)
Sequential administration of recombinant human interleukin-2 and dacarbazine in metastatic melanoma: a multicenter phase II study
J Clin Oncol, 9 (9), 1687-91
PubMed 1875225

Publications 1990

Tefre T, Børresen AL, Aamdal S, Brøgger A (1990)
Studies of the L-myc DNA polymorphism and relation to metastasis in Norwegian lung cancer patients
Br J Cancer, 61 (6), 809-12
PubMed 1973618

Wibe E, Paus E, Aamdal S (1990)
Neuron specific enolase (NSE) in serum of patients with malignant melanoma
Cancer Lett, 52 (1), 29-31
PubMed 2354416

Publications 1989

Stoter G, Shiloni E, Aamdal S, Cleton FJ, Iacobelli S, Bijman JT, Palmer P, Franks CR, Rodenhuis S (1989)
Sequential administration of recombinant human interleukin-2 and dacarbazine in metastatic melanoma. A multicentre phase II study
Eur J Cancer Clin Oncol, 25 Suppl 3, S41-3
PubMed 2697578

Publications 1988

Fodstad O, Kjønniksen I, Aamdal S, Nesland JM, Boyd MR, Pihl A (1988)
Extrapulmonary, tissue-specific metastasis formation in nude mice injected with FEMX-I human melanoma cells
Cancer Res, 48 (15), 4382-8
PubMed 3390834

Fodstad O, Aamdal S, McMenamin M, Nesland JM, Pihl A (1988)
A new experimental metastasis model in athymic nude mice, the human malignant melanoma LOX
Int J Cancer, 41 (3), 442-9
PubMed 3346110

Aamdal S, Fodstad O, Pihl A (1988)
Sodium thiosulfate fails to increase the therapeutic index of intravenously administered cis-diamminedichloroplatinum (II) in mice bearing murine and human tumors
Cancer Chemother Pharmacol, 21 (2), 129-33
PubMed 3349560

Publications 1987

Gundersen S, Aamdal S, Fodstad O (1987)
Mitozolomide (NSC 353451), a new active drug in the treatment of malignant melanoma. Phase II trial in patients with advanced disease
Br J Cancer, 55 (4), 433-5
PubMed 3580266

Aamdal S, Fodstad O, Pihl A (1987)
Some procedures to reduce cis-platinum toxicity reduce antitumour activity
Cancer Treat Rev, 14 (3-4), 389-95
PubMed 3326670

Publications 1986

Aamdal S, Fodstad O, Kaalhus O, Pihl A (1986)
Chemosensitivity profiles of human cancers assessed by the 6-day SRC assay on serially xenografted tumors
Int J Cancer, 37 (4), 579-87
PubMed 3957463

Publications 1985

Fodstad O, Aamdal S, Pihl A, Boyd MR (1985)
Activity of mitozolomide (NSC 353451), a new imidazotetrazine, against xenografts from human melanomas, sarcomas, and lung and colon carcinomas
Cancer Res, 45 (4), 1778-86
PubMed 3978640

Aamdal S, Fodstad O, Nesland JM, Pihl A (1985)
Characteristics of human tumour xenografts transplanted under the renal capsule of immunocompetent mice
Br J Cancer, 51 (3), 347-56
PubMed 3970811

Aamdal S, Fodstad O, Pihl A (1985)
The six-day subrenal capsule assay (SRCA) for testing the response of human tumours to anticancer agents. Validity and usefulness in cancer research and treatment
Ann Chir Gynaecol Suppl, 199, 51-9
PubMed 3864392

Aamdal S, Fodstad O, Pihl A (1985)
Methodological aspects of the 6-day subrenal capsule assay for measuring the response of human tumors to anticancer agents
Anticancer Res, 5 (4), 329-37
PubMed 4037730

Publications 1984

Fodstad O, Kvalheim G, Godal A, Lotsberg J, Aamdal S, Høst H, Pihl A (1984)
Phase I study of the plant protein ricin
Cancer Res, 44 (2), 862-5
PubMed 6692385

Aamdal S, Børmer O, Jørgensen O, Høst H, Eliassen G, Kaalhus O, Pihl A (1984)
Estrogen receptors and long-term prognosis in breast cancer
Cancer, 53 (11), 2525-9
PubMed 6713348

Aamdal S, Fodstad O, Kaalhus O, Pihl A (1984)
Reduced antineoplastic activity in mice of cisplatin administered with high salt concentration in the vehicle
J Natl Cancer Inst, 73 (3), 743-52
PubMed 6590919

Aamdal S, Fodstad O, Pihl A (1984)
Human tumor xenografts transplanted under the renal capsule of conventional mice. Growth rates and host immune response
Int J Cancer, 34 (5), 725-30
PubMed 6500747