Publications by Anette Weyergang
41 publications found
Publications 2024
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Corrigendum: Light-enhanced VEGF121/rGel induce immunogenic cell death and increase the antitumor activity of αCTLA4 treatment
Front Immunol, 14, 1359973
DOI 10.3389/fimmu.2023.1359973, PubMed 38264651
Publications 2023
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Light-enhanced VEGF121/rGel induce immunogenic cell death and increase the antitumor activity of αCTLA4 treatment
Front Immunol, 14, 1278000
DOI 10.3389/fimmu.2023.1278000, PubMed 38173721
Publications 2021
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RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
Nat Commun, 12 (1), 6427
DOI 10.1038/s41467-021-26018-z, PubMed 34741021 -
Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
Biochem Pharmacol, 194, 114837
DOI 10.1016/j.bcp.2021.114837, PubMed 34780750
Publications 2020
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Production of Recombinant Gelonin Using an Automated Liquid Chromatography System
Toxins (Basel), 12 (8)
DOI 10.3390/toxins12080519, PubMed 32823678 -
Photochemical Internalization for Intracellular Drug Delivery. From Basic Mechanisms to Clinical Research
J Clin Med, 9 (2)
DOI 10.3390/jcm9020528, PubMed 32075165 -
Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy
Cancers (Basel), 12 (2)
DOI 10.3390/cancers12020417, PubMed 32053965
Publications 2019
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Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization
J Clin Med, 9 (1)
DOI 10.3390/jcm9010068, PubMed 31888091
Publications 2018
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Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins
Photochem Photobiol Sci, 17 (5), 539-551
DOI 10.1039/C7PP00358G, PubMed 29565434 -
Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy
J Control Release, 288, 161-172
DOI 10.1016/j.jconrel.2018.09.005, PubMed 30217739
Publications 2017
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Photochemical delivery of bleomycin induces T-cell activation of importance for curative effect and systemic anti-tumor immunity
J Control Release, 268, 120-127
DOI 10.1016/j.jconrel.2017.10.015, PubMed 29042319 -
Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
Biochem Pharmacol, 144, 63-77
DOI 10.1016/j.bcp.2017.08.002, PubMed 28784290
Publications 2015
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Design of an EGFR-targeting toxin for photochemical delivery: in vitro and in vivo selectivity and efficacy
Oncogene, 34 (44), 5582-92
DOI 10.1038/onc.2015.15, PubMed 25684137 -
Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer
Oncotarget, 6 (14), 12436-51
DOI 10.18632/oncotarget.3814, PubMed 26002552 -
Photochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics
Photochem Photobiol Sci, 14 (8), 1433-50
DOI 10.1039/c5pp00027k, PubMed 25805311 -
Photochemical activation of drugs for the treatment of therapy-resistant cancers
Photochem Photobiol Sci, 14 (8), 1465-75
DOI 10.1039/c5pp00029g, PubMed 25849953
Publications 2014
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Light-triggered, efficient cytosolic release of IM7-saporin targeting the putative cancer stem cell marker CD44 by photochemical internalization
Mol Pharm, 11 (8), 2764-76
DOI 10.1021/mp500129t, PubMed 24960585 -
Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome
J Control Release, 182, 58-66
DOI 10.1016/j.jconrel.2014.03.014, PubMed 24637464 -
Photochemical internalization augments tumor vascular cytotoxicity and specificity of VEGF(121)/rGel fusion toxin
J Control Release, 180, 1-9
DOI 10.1016/j.jconrel.2014.02.003, PubMed 24531010
Publications 2013
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Circumvention of resistance to photodynamic therapy in doxorubicin-resistant sarcoma by photochemical internalization of gelonin
Free Radic Biol Med, 65, 1300-1309
DOI 10.1016/j.freeradbiomed.2013.09.010, PubMed 24076428 -
Vascular endothelial cells as targets for photochemical internalization (PCI)
Photochem Photobiol, 89 (5), 1185-92
DOI 10.1111/php.12126, PubMed 23819771 -
Sustained ERK [corrected] inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy
Biochim Biophys Acta, 1830 (3), 2659-70
DOI 10.1016/j.bbagen.2012.11.010, PubMed 23671927 -
Sustained ERK inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy (vol 1830, pg 2659, 2013)
Biochim. Biophys. Acta-Gen. Subj., 1830 (10), 4417
DOI 10.1016/j.bbagen.2013.05.002
Publications 2012
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Photochemical internalization (PCI) of HER2-targeted toxins: synergy is dependent on the treatment sequence
Biochim Biophys Acta, 1820 (12), 1849-58
DOI 10.1016/j.bbagen.2012.08.027, PubMed 22981913 -
Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug
J Control Release, 159 (2), 197-203
DOI 10.1016/j.jconrel.2012.02.003, PubMed 22349185
Publications 2011
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Photochemical internalization of tumor-targeted protein toxins
Lasers Surg Med, 43 (7), 721-33
DOI 10.1002/lsm.21084, PubMed 22057500
Publications 2010
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Photochemical internalization: a new tool for gene and oligonucleotide delivery
Top Curr Chem, 296, 251-81
DOI 10.1007/128_2010_63, PubMed 21504105 -
Photochemical internalization (PCI): a technology for drug delivery
Methods Mol Biol, 635, 133-45
DOI 10.1007/978-1-60761-697-9_10, PubMed 20552345 -
Photochemical internalization provides time- and space-controlled endolysosomal escape of therapeutic molecules
J Control Release, 148 (1), 2-12
DOI 10.1016/j.jconrel.2010.06.008, PubMed 20600406
Publications 2009
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Photochemical internalization (PCI) in cancer therapy: from bench towards bedside medicine
J Photochem Photobiol B, 96 (2), 83-92
DOI 10.1016/j.jphotobiol.2009.04.012, PubMed 19467605 -
Photodynamic therapy targets the mTOR signaling network in vitro and in vivo
Mol Pharm, 6 (1), 255-64
DOI 10.1021/mp800156e, PubMed 19125612
Publications 2008
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Photodynamic therapy with an endocytically located photosensitizer cause a rapid activation of the mitogen-activated protein kinases extracellular signal-regulated kinase, p38, and c-Jun NH2 terminal kinase with opposing effects on cell survival
Mol Cancer Ther, 7 (6), 1740-50
DOI 10.1158/1535-7163.MCT-08-0020, PubMed 18566245 -
Photodynamic targeting of EGFR does not predict the treatment outcome in combination with the EGFR tyrosine kinase inhibitor Tyrphostin AG1478
Photochem Photobiol Sci, 7 (9), 1032-40
DOI 10.1039/b806209a, PubMed 18754049
Publications 2007
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Photochemical internalization: a new tool for drug delivery
Curr Pharm Biotechnol, 8 (6), 362-72
DOI 10.2174/138920107783018354, PubMed 18289045 -
Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor
Biochem Pharmacol, 74 (2), 226-35
DOI 10.1016/j.bcp.2007.04.018, PubMed 17531956 -
Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells
Mol Pharm, 4 (2), 241-51
DOI 10.1021/mp060105u, PubMed 17263556
Publications 2006
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Photochemical internalization (PCI): A novel technology for activation of endocytosed therapeutic agents.
Med Laser Appl, 21, 239-251
DOI 10.1016/j.mla.2006.08.004, PublikaID 73 -
Photochemical internalization (PCI): a new modality for light activation of endocytosed therapeuticals
J Environ Pathol Toxicol Oncol, 25 (1-2), 521-36
DOI 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.330, PubMed 16566739 -
Photochemical internalization of therapeutic macromolecular agents: a novel strategy to kill multidrug-resistant cancer cells
J Pharmacol Exp Ther, 319 (2), 604-12
DOI 10.1124/jpet.106.109165, PubMed 16902053 -
Photochemically stimulated drug delivery increases the cytotoxicity and specificity of EGF-saporin
J Control Release, 111 (1-2), 165-73
DOI 10.1016/j.jconrel.2005.12.002, PubMed 16466823
Publications 2005
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Porphyrin-related photosensitizers for cancer imaging and therapeutic applications
J Microsc, 218 (Pt 2), 133-47
DOI 10.1111/j.1365-2818.2005.01471.x, PubMed 15857375