Publications

Publications published since 2003 from OUS - Dept. of Microbiology, Tønjum - Genome dynamics

79 publications found

Publications 2024

1. Alkaltham MF, Almansour AI, Arumugam N, Vagolu SK, Tønjum T, Alaqeel SI, Rajaratnam S, Sivaramakrishnan V (2024)
   Activity against Mycobacterium tuberculosis of a new class of spirooxindolopyrrolidine embedded chromanone hybrid heterocycles
   RSC Adv, 14 (17), 11604-11613
   DOI 10.1039/d4ra01501k, PubMed 38605893
2. Birhanu AG, Riaz T, Støen M, Tønjum T (2024)
   Differential Abundance of Protein Acylation in Mycobacterium tuberculosis Under Exposure to Nitrosative Stress
   Proteomics Clin Appl, 18 (6), e202300212
   DOI 10.1002/prca.202300212, PubMed 39082596
3. Cao D, Jiang X, Wu T, Xiang Y, Liu J, Li Z, Yuan X, Bi K, Dong X, Tønjum T, Xu K, Zhang Y (2024)
   Identification of essential oils with strong activity against stationary phase Mycobacterium abscessus
   Heliyon, 10 (5), e27073
   DOI 10.1016/j.heliyon.2024.e27073, PubMed 38463856
4. Cao D, Yuan X, Jiang X, Wu T, Xiang Y, Ji Z, Liu J, Dong X, Bi K, Tønjum T, Xu K, Zhang Y (2024)
   Antimicrobial and Antibiofilm Effects of Bithionol against Mycobacterium abscessus
   Antibiotics (Basel), 13 (6)
   DOI 10.3390/antibiotics13060529, PubMed 38927195
5. Girase RT, Ahmad I, Oh JM, Mathew B, Vagolu SK, Tønjum T, Sriram D, Kumari J, Desai NC, Agrawal Y, Kim H, Patel HM (2024)
   Design and Synthesis of the Linezolid Bioisosteres to Resolve the Serotonergic Toxicity Associated with Linezolid
   ACS Med Chem Lett, 15 (6), 924-937
   DOI 10.1021/acsmedchemlett.4c00114, PubMed 38894926

Publications 2023

1. Girase RT, Ahmad I, Oh JM, Kim H, Mathew B, Vagolu SK, Tønjum T, Desai NC, Sriram D, Kumari J, Patel HM (2023)
   Repurposing Azoles to Resolve Serotogenic Toxicity Associated with Linezolid to Combat Multidrug-Resistant Tuberculosis
   ACS Med Chem Lett, 14 (12), 1754-1759
   DOI 10.1021/acsmedchemlett.3c00406, PubMed 38116435
2. Sarkar S, Mayer Bridwell AE, Good JAD, Wang ER, McKee SR, Valenta J, Harrison GA, Flentie KN, Henry FL, Wixe T, Demirel P, Vagolu SK, Chatagnon J, Machelart A, Brodin P, Tønjum T, Stallings CL, Almqvist F (2023)
   Design, Synthesis, and Evaluation of Novel Δ²-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant
   J Med Chem, 66 (16), 11056-11077
   DOI 10.1021/acs.jmedchem.3c00358, PubMed 37485869
3. Özcan E, Vagolu SK, Gündüz MG, Stevanovic M, Kökbudak Z, Tønjum T, Nikodinovic-Runic J, Çetinkaya Y, Doğan ŞD (2023)
   Novel Quinoline-Based Thiosemicarbazide Derivatives: Synthesis, DFT Calculations, and Investigation of Antitubercular, Antibacterial, and Antifungal Activities
   ACS Omega, 8 (43), 40140-40152
   DOI 10.1021/acsomega.3c03018, PubMed 37929089

Publications 2022

1. Birhanu AG, Gómez-Muñoz M, Kalayou S, Riaz T, Lutter T, Yimer SA, Abebe M, Tønjum T (2022)
   Proteome Profiling of Mycobacterium tuberculosis Cells Exposed to Nitrosative Stress
   ACS Omega, 7 (4), 3470-3482
   DOI 10.1021/acsomega.1c05923, PubMed 35128256
2. Keleş Atıcı R, Doğan ŞD, Gündüz MG, Krishna VS, Chebaiki M, Homberset H, Lherbet C, Mourey L, Tønjum T (2022)
   Urea derivatives carrying a thiophenylthiazole moiety: Design, synthesis, and evaluation of antitubercular and InhA inhibitory activities
   Drug Dev Res, 83 (6), 1292-1304
   DOI 10.1002/ddr.21958, PubMed 35769019
3. Koçak Aslan E, Han Mİ, Krishna VS, Tamhaev R, Dengiz C, Doğan ŞD, Lherbet C, Mourey L, Tønjum T, Gündüz MG (2022)
   Isoniazid Linked to Sulfonate Esters via Hydrazone Functionality: Design, Synthesis, and Evaluation of Antitubercular Activity
   Pharmaceuticals (Basel), 15 (10)
   DOI 10.3390/ph15101301, PubMed 36297413
4. Koçak Aslan E, Vagolu SK, Armakovic SJ, Armakovic S, Sahin O, Tønjum T, Gündüz MG (2022)
   Linking azoles to isoniazid via hydrazone bridge: Synthesis, crystal structure determination, antitubercular evaluation and computational studies
   Journal of Molecular Liquids, 354, 118873
   DOI 10.1016/j.molliq.2022.118873, PublikaID 422
5. Tapera M, Kekeçmuhammed H, Sahin K, Vagolu SK, Lherbet C, Homberset H, Chebaiki M, Tønjum T, Mourey L, Zorlu Y, Durdagi S, Sarıpınar E (2022)
   Synthesis, characterization, anti-tuberculosis activity and molecular modeling studies of thiourea derivatives bearing aminoguanidine moiety
   Journal of Molecular Structure, 1270, 133899
   DOI 10.1016/j.molstruc.2022.133899, PublikaID 421

Publications 2021

1. Johansen TEB, Cai T, Naber K, Nicolle LE, Tandogdu Z, Tønjum T, Wagenlehner F, Zahl PH, Koves B (2021)
   [Pregnant women should be screened for asymptomatic bacteriuria]
   Tidsskr Nor Laegeforen, 141 (11)
   DOI 10.4045/tidsskr.21.0379, PubMed 34423934
2. Mekonnen D, Derbie A, Mihret A, Yimer SA, Tønjum T, Gelaw B, Nibret E, Munshae A, Waddell SJ, Aseffa A (2021)
   Lipid droplets and the transcriptome of Mycobacterium tuberculosis from direct sputa: a literature review
   Lipids Health Dis, 20 (1), 129
   DOI 10.1186/s12944-021-01550-5, PubMed 34602073
3. Welekidan LN, Skjerve E, Dejene TA, Gebremichael MW, Brynildsrud O, Agdestein A, Tessema GT, Tønjum T, Yimer SA (2021)
   Correction: Characteristics of pulmonary multidrug-resistant tuberculosis patients in Tigray Region, Ethiopia: A cross-sectional study
   PLoS One, 16 (10), e0258457
   DOI 10.1371/journal.pone.0258457, PubMed 34614019
4. Welekidan LN, Yimer SA, Skjerve E, Dejene TA, Homberset H, Tønjum T, Brynildsrud O (2021)
   Whole Genome Sequencing of Drug Resistant and Drug Susceptible Mycobacterium tuberculosis Isolates From Tigray Region, Ethiopia
   Front Microbiol, 12, 743198
   DOI 10.3389/fmicb.2021.743198, PubMed 34938276

Publications 2020

1. Andersson DI, Balaban NQ, Baquero F, Courvalin P, Glaser P, Gophna U, Kishony R, Molin S, Tønjum T (2020)
   Antibiotic resistance: turning evolutionary principles into clinical reality
   FEMS Microbiol Rev, 44 (2), 171-188
   DOI 10.1093/femsre/fuaa001, PubMed 31981358
2. Navarro JF, Croteau DL, Jurek A, Andrusivova Z, Yang B, Wang Y, Ogedegbe B, Riaz T, Støen M, Desler C, Rasmussen LJ, Tønjum T, Galas MC, Lundeberg J, Bohr VA (2020)
   Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
   iScience, 23 (10), 101556
   DOI 10.1016/j.isci.2020.101556, PubMed 33083725
3. Welekidan LN, Skjerve E, Dejene TA, Gebremichael MW, Brynildsrud O, Agdestein A, Tessema GT, Tønjum T, Yimer SA (2020)
   Characteristics of pulmonary multidrug-resistant tuberculosis patients in Tigray Region, Ethiopia: A cross-sectional study
   PLoS One, 15 (8), e0236362
   DOI 10.1371/journal.pone.0236362, PubMed 32797053
4. Welekidan LN, Skjerve E, Dejene TA, Gebremichael MW, Brynildsrud O, Tønjum T, Yimer SA (2020)
   Frequency and patterns of first- and second-line drug resistance-conferring mutations in Mycobacterium tuberculosis isolated from pulmonary tuberculosis patients in a cross-sectional study in Tigray Region, Ethiopia
   J Glob Antimicrob Resist, 24, 6-13
   DOI 10.1016/j.jgar.2020.11.017, PubMed 33279682
5. Yimer SA, Kalayou S, Homberset H, Birhanu AG, Riaz T, Zegeye ED, Lutter T, Abebe M, Holm-Hansen C, Aseffa A, Tønjum T (2020)
   Lineage-Specific Proteomic Signatures in the Mycobacterium tuberculosis Complex Reveal Differential Abundance of Proteins Involved in Virulence, DNA Repair, CRISPR-Cas, Bioenergetics and Lipid Metabolism
   Front Microbiol, 11, 550760
   DOI 10.3389/fmicb.2020.550760, PubMed 33072011

Publications 2019

1. Shi W, Cui P, Niu H, Zhang S, Tønjum T, Zhu B, Zhang Y (2019)
   Introducing RpsA Point Mutations Δ438A and D123A into the Chromosome of Mycobacterium tuberculosis Confirms Their Role in Causing Resistance to Pyrazinamide
   Antimicrob Agents Chemother, 63 (6)
   DOI 10.1128/AAC.02681-18, PubMed 30858213

Publications 2018

1. Alfsnes K, Frye SA, Eriksson J, Eldholm V, Brynildsrud OB, Bohlin J, Harrison OB, Hood DW, Maiden MCJ, Tønjum T, Ambur OH (2018)
   A genomic view of experimental intraspecies and interspecies transformation of a rifampicin-resistance allele into Neisseria meningitidis
   Microb Genom, 4 (11)
   DOI 10.1099/mgen.0.000222, PubMed 30251949
2. Desler C, Lillenes MS, Tønjum T, Rasmussen LJ (2018)
   The Role of Mitochondrial Dysfunction in the Progression of Alzheimer's Disease
   Curr Med Chem, 25 (40), 5578-5587
   DOI 10.2174/0929867324666170616110111, PubMed 28618998
3. Jensen HLB, Lillenes MS, Rabano A, Günther CC, Riaz T, Kalayou ST, Ulstein ID, Bøhmer T, Tønjum T (2018)
   Expression of nucleotide excision repair in Alzheimer's disease is higher in brain tissue than in blood
   Neurosci Lett, 672, 53-58
   DOI 10.1016/j.neulet.2018.02.043, PubMed 29474873

Publications 2017

1. Beyene GT, Kalayou S, Riaz T, Tonjum T (2017)
   Comparative proteomic analysis of Neisseria meningitidis wildtype and dprA null mutant strains links DNA processing to pilus biogenesis
   BMC Microbiol, 17 (1), 96
   DOI 10.1186/s12866-017-1004-8, PubMed 28431522
2. Birhanu AG, Yimer SA, Holm-Hansen C, Norheim G, Aseffa A, Abebe M, Tønjum T (2017)
   N_ε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains: Proteins Involved in Bioenergetics, Virulence, and Antimicrobial Resistance Are Acetylated
   J Proteome Res, 16 (11), 4045-4059
   DOI 10.1021/acs.jproteome.7b00429, PubMed 28920697
3. Castañeda-García A, Prieto AI, Rodríguez-Beltrán J, Alonso N, Cantillon D, Costas C, Pérez-Lago L, Zegeye ED, Herranz M, Plociński P, Tonjum T, García de Viedma D, Paget M, Waddell SJ, Rojas AM, Doherty AJ, Blázquez J (2017)
   A non-canonical mismatch repair pathway in prokaryotes
   Nat Commun, 8, 14246
   DOI 10.1038/ncomms14246, PubMed 28128207
4. Frye SA, Beyene GT, Namouchi A, Gómez-Muñoz M, Homberset H, Kalayou S, Riaz T, Tønjum T, Balasingham SV (2017)
   The helicase DinG responds to stress due to DNA double strand breaks
   PLoS One, 12 (11), e0187900
   DOI 10.1371/journal.pone.0187900, PubMed 29121674
5. Hovland E, Beyene GT, Frye SA, Homberset H, Balasingham SV, Gómez-Muñoz M, Derrick JP, Tønjum T, Ambur OH (2017)
   DprA from Neisseria meningitidis: properties and role in natural competence for transformation
   Microbiology (Reading), 163 (7), 1016-1029
   DOI 10.1099/mic.0.000489, PubMed 28696187
6. Lillenes MS, Støen M, Günther CC, Selnes P, Stenset VT, Espeseth T, Reinvang I, Fladby T, Tønjum T (2017)
   Mitochondrial transcription factor A (TFAM) rs1937 and AP endonuclease 1 (APE1) rs1130409 alleles are associated with reduced cognitive performance
   Neurosci Lett, 645, 46-52
   DOI 10.1016/j.neulet.2017.02.062, PubMed 28242328
7. Norheim G, Seterelv S, Arnesen TM, Mengshoel AT, Tønjum T, Rønning JO, Eldholm V (2017)
   Tuberculosis Outbreak in an Educational Institution in Norway
   J Clin Microbiol, 55 (5), 1327-1333
   DOI 10.1128/JCM.01152-16, PubMed 28202795
8. Yimer SA, Birhanu AG, Kalayou S, Riaz T, Zegeye ED, Beyene GT, Holm-Hansen C, Norheim G, Abebe M, Aseffa A, Tønjum T (2017)
   Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence
   Front Microbiol, 8, 795
   DOI 10.3389/fmicb.2017.00795, PubMed 28536560

Publications 2016

1. Beyene GT, Balasingham SV, Frye SA, Namouchi A, Homberset H, Kalayou S, Riaz T, Tønjum T (2016)
   Characterization of the Neisseria meningitidis Helicase RecG
   PLoS One, 11 (10), e0164588
   DOI 10.1371/journal.pone.0164588, PubMed 27736945
2. Lillenes MS, Rabano A, Støen M, Riaz T, Misaghian D, Møllersen L, Esbensen Y, Günther CC, Selnes P, Stenset VT, Fladby T, Tønjum T (2016)
   Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease
   Mol Brain, 9 (1), 61
   DOI 10.1186/s13041-016-0237-z, PubMed 27234294
3. Namouchi A, Gómez-Muñoz M, Frye SA, Moen LV, Rognes T, Tønjum T, Balasingham SV (2016)
   The Mycobacterium tuberculosis transcriptional landscape under genotoxic stress
   BMC Genomics, 17 (1), 791
   DOI 10.1186/s12864-016-3132-1, PubMed 27724857
4. Yimer SA, Namouchi A, Zegeye ED, Holm-Hansen C, Norheim G, Abebe M, Aseffa A, Tønjum T (2016)
   Deciphering the recent phylogenetic expansion of the originally deeply rooted Mycobacterium tuberculosis lineage 7
   BMC Evol Biol, 16 (1), 146
   DOI 10.1186/s12862-016-0715-z, PubMed 27363525
5. Zegeye N, Asrat D, Woldeamanuel Y, Habte A, Gedlu E, Tønjum T, Aseffa A (2016)
   Throat culture positivity rate and antibiotic susceptibility pattern of beta-hemolytic streptococci in children on secondary prophylaxis for rheumatic heart disease
   BMC Infect Dis, 16 (1), 510
   DOI 10.1186/s12879-016-1841-3, PubMed 27663649

Publications 2015

1. Dahlberg D, Mariussen E, Goverud IL, Tønjum T, Mæhlen J, Antal EA, Hassel B (2015)
   Staphylococcal α-hemolysin is neurotoxic and causes lysis of brain cells in vivo and in vitro
   Neurotoxicology, 48, 61-7
   DOI 10.1016/j.neuro.2015.03.001, PubMed 25757835
2. Frye SA, Lång E, Beyene GT, Balasingham SV, Homberset H, Rowe AD, Ambur OH, Tønjum T (2015)
   The Inner Membrane Protein PilG Interacts with DNA and the Secretin PilQ in Transformation
   PLoS One, 10 (8), e0134954
   DOI 10.1371/journal.pone.0134954, PubMed 26248334
3. Ricanek P, Lunde LK, Frye SA, Støen M, Nygård S, Morth JP, Rydning A, Vatn MH, Amiry-Moghaddam M, Tønjum T (2015)
   Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease
   Clin Exp Gastroenterol, 8, 49-67
   DOI 10.2147/CEG.S70119, PubMed 25624769
4. Yimer SA, Norheim G, Namouchi A, Zegeye ED, Kinander W, Tønjum T, Bekele S, Mannsåker T, Bjune G, Aseffa A, Holm-Hansen C (2015)
   Mycobacterium tuberculosis lineage 7 strains are associated with prolonged patient delay in seeking treatment for pulmonary tuberculosis in Amhara Region, Ethiopia
   J Clin Microbiol, 53 (4), 1301-9
   DOI 10.1128/JCM.03566-14, PubMed 25673798

Publications 2014

1. Alfsnes K, Raynaud X, Tønjum T, Ambur OH (2014)
   Mathematical and live meningococcal models for simple sequence repeat dynamics - coherent predictions and observations
   PLoS One, 9 (7), e101637
   DOI 10.1371/journal.pone.0101637, PubMed 24999629
2. Hassel B, Dahlberg D, Mariussen E, Goverud IL, Antal EA, Tønjum T, Maehlen J (2014)
   Brain infection with Staphylococcus aureus leads to high extracellular levels of glutamate, aspartate, γ-aminobutyric acid, and zinc
   J Neurosci Res, 92 (12), 1792-800
   DOI 10.1002/jnr.23444, PubMed 25043715
3. Mantaka P, Tønjum T, Gjersvik P (2014)
   [A knot on the aquarium owner's hand]
   Tidsskr Nor Laegeforen, 134 (7), 715
   DOI 10.4045/tidsskr.13.1425, PubMed 24721859
4. Zaburdaev V, Biais N, Schmiedeberg M, Eriksson J, Jonsson AB, Sheetz MP, Weitz DA (2014)
   Uncovering the mechanism of trapping and cell orientation during Neisseria gonorrhoeae twitching motility
   Biophys J, 107 (7), 1523-31
   DOI 10.1016/j.bpj.2014.07.061, PubMed 25296304

Publications 2013

1. Frye SA, Nilsen M, Tønjum T, Ambur OH (2013)
   Dialects of the DNA uptake sequence in Neisseriaceae
   PLoS Genet, 9 (4), e1003458
   DOI 10.1371/journal.pgen.1003458, PubMed 23637627

Publications 2012

1. Ambur OH, Frye SA, Nilsen M, Hovland E, Tønjum T (2012)
   Restriction and sequence alterations affect DNA uptake sequence-dependent transformation in Neisseria meningitidis
   PLoS One, 7 (7), e39742
   DOI 10.1371/journal.pone.0039742, PubMed 22768309
2. Balasingham SV, Zegeye ED, Homberset H, Rossi ML, Laerdahl JK, Bohr VA, Tønjum T (2012)
   Enzymatic activities and DNA substrate specificity of Mycobacterium tuberculosis DNA helicase XPB
   PLoS One, 7 (5), e36960
   DOI 10.1371/journal.pone.0036960, PubMed 22615856
3. Ricanek P, Lothe SM, Frye SA, Rydning A, Vatn MH, Tønjum T (2012)
   Gut bacterial profile in patients newly diagnosed with treatment-naïve Crohn's disease
   Clin Exp Gastroenterol, 5, 173-86
   DOI 10.2147/CEG.S33858, PubMed 23049264
4. Zegeye ED, Balasingham SV, Laerdahl JK, Homberset H, Tønjum T (2012)
   Mycobacterium tuberculosis RecG binds and unwinds model DNA substrates with a preference for Holliday junctions
   Microbiology (Reading), 158 (Pt 8), 1982-1993
   DOI 10.1099/mic.0.058693-0, PubMed 22628485

Publications 2011

1. Ricanek P, Rydning A, Vatn MH, Tonjum T (2011)
   Considered "negative" for MAP, these results would be very "positive" for tuberculoid leprosy Reply
   J. Crohns Colitis, 5 (4), 374
   DOI 10.1016/j.crohns.2011.04.007
2. Yang M, Aamodt RM, Dalhus B, Balasingham S, Helle I, Andersen P, Tønjum T, Alseth I, Rognes T, Bjørås M (2011)
   The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage
   DNA Repair (Amst), 10 (6), 595-602
   DOI 10.1016/j.dnarep.2011.03.007, PubMed 21570366

Publications 2010

1. Ricanek P, Lothe SM, Szpinda I, Jorde AT, Brackmann S, Perminow G, Jørgensen KK, Rydning A, Vatn MH, Tønjum T, IBSEN II study group (2010)
   Paucity of mycobacteria in mucosal bowel biopsies from adults and children with early inflammatory bowel disease
   J Crohns Colitis, 4 (5), 561-6
   DOI 10.1016/j.crohns.2010.05.003, PubMed 21122560

Publications 2009

1. Ambur OH, Davidsen T, Frye SA, Balasingham SV, Lagesen K, Rognes T, Tønjum T (2009)
   Genome dynamics in major bacterial pathogens
   FEMS Microbiol Rev, 33 (3), 453-70
   DOI 10.1111/j.1574-6976.2009.00173.x, PubMed 19396949
2. Balasingham SV, Davidsen T, Szpinda I, Frye SA, Tønjum T (2009)
   Molecular diagnostics in tuberculosis: basis and implications for therapy
   Mol Diagn Ther, 13 (3), 137-51
   DOI 10.1007/BF03256322, PubMed 19650669
3. Dos Vultos T, Mestre O, Tonjum T, Gicquel B (2009)
   DNA repair in Mycobacterium tuberculosis revisited
   FEMS Microbiol Rev, 33 (3), 471-87
   DOI 10.1111/j.1574-6976.2009.00170.x, PubMed 19385996
4. Olsen I, Balasingham SV, Davidsen T, Debebe E, Rødland EA, van Soolingen D, Kremer K, Alseth I, Tønjum T (2009)
   Characterization of the major formamidopyrimidine-DNA glycosylase homolog in Mycobacterium tuberculosis and its linkage to variable tandem repeats
   FEMS Immunol Med Microbiol, 56 (2), 151-61
   DOI 10.1111/j.1574-695X.2009.00562.x, PubMed 19496823
5. Tibballs KL, Ambur OH, Alfsnes K, Homberset H, Frye SA, Davidsen T, Tønjum T (2009)
   Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair
   BMC Microbiol, 9, 7
   DOI 10.1186/1471-2180-9-7, PubMed 19134198

Publications 2008

1. Dos Vultos T, Mestre O, Rauzier J, Golec M, Rastogi N, Rasolofo V, Tonjum T, Sola C, Matic I, Gicquel B (2008)
   Evolution and diversity of clonal bacteria: the paradigm of Mycobacterium tuberculosis
   PLoS One, 3 (2), e1538
   DOI 10.1371/journal.pone.0001538, PubMed 18253486
2. Glosli H, Stray-Pedersen A, Brun AC, Holtmon LW, Tønjum T, Chapgier A, Casanova JL, Abrahamsen TG (2008)
   Infections due to various atypical mycobacteria in a Norwegian multiplex family with dominant interferon-gamma receptor deficiency
   Clin Infect Dis, 46 (3), e23-7
   DOI 10.1086/525855, PubMed 18171304
3. Treangen TJ, Ambur OH, Tonjum T, Rocha EP (2008)
   The impact of the neisserial DNA uptake sequences on genome evolution and stability
   Genome Biol, 9 (3), R60
   DOI 10.1186/gb-2008-9-3-r60, PubMed 18366792

Publications 2007

1. Balasingham SV, Collins RF, Assalkhou R, Homberset H, Frye SA, Derrick JP, Tønjum T (2007)
   Interactions between the lipoprotein PilP and the secretin PilQ in Neisseria meningitidis
   J Bacteriol, 189 (15), 5716-27
   DOI 10.1128/JB.00060-07, PubMed 17526700
2. Bohr VA, Ottersen OP, Tønjum T (2007)
   Genome instability and DNA repair in brain, ageing and neurological disease
   Neuroscience, 145 (4), 1183-6
   DOI 10.1016/j.neuroscience.2007.03.015, PubMed 17400394
3. Davidsen T, Amundsen EK, Rødland EA, Tønjum T (2007)
   DNA repair profiles of disease-associated isolates of Neisseria meningitidis
   FEMS Immunol Med Microbiol, 49 (2), 243-51
   DOI 10.1111/j.1574-695X.2006.00195.x, PubMed 17284282
4. Davidsen T, Koomey M, Tønjum T (2007)
   Microbial genome dynamics in CNS pathogenesis
   Neuroscience, 145 (4), 1375-87
   DOI 10.1016/j.neuroscience.2007.01.059, PubMed 17367950
5. Davidsen T, Tuven HK, Bjørås M, Rødland EA, Tønjum T (2007)
   Genetic interactions of DNA repair pathways in the pathogen Neisseria meningitidis
   J Bacteriol, 189 (15), 5728-37
   DOI 10.1128/JB.00161-07, PubMed 17513474

Publications 2006

1. Ambur OH, Frye SA, Tønjum T (2006)
   New functional identity for the DNA uptake sequence in transformation and its presence in transcriptional terminators
   J Bacteriol, 189 (5), 2077-85
   DOI 10.1128/JB.01408-06, PubMed 17194793
2. Davidsen T, Tønjum T (2006)
   Meningococcal genome dynamics
   Nat Rev Microbiol, 4 (1), 11-22
   DOI 10.1038/nrmicro1324, PubMed 16357857
3. Golovanov AP, Balasingham S, Tzitzilonis C, Goult BT, Lian LY, Homberset H, Tønjum T, Derrick JP (2006)
   Assignment of 1H, 13C, and 15N resonances for the PilP pilot protein from Neisseria meningitidis
   J Biomol NMR, 36 Suppl 1, 68
   DOI 10.1007/s10858-006-9054-5, PubMed 16933020
4. Golovanov AP, Balasingham S, Tzitzilonis C, Goult BT, Lian LY, Homberset H, Tønjum T, Derrick JP (2006)
   The solution structure of a domain from the Neisseria meningitidis lipoprotein PilP reveals a new beta-sandwich fold
   J Mol Biol, 364 (2), 186-95
   DOI 10.1016/j.jmb.2006.08.078, PubMed 17007878
5. Vicente M, Hodgson J, Massidda O, Tonjum T, Henriques-Normark B, Ron EZ (2006)
   The fallacies of hope: will we discover new antibiotics to combat pathogenic bacteria in time?
   FEMS Microbiol Rev, 30 (6), 841-52
   DOI 10.1111/j.1574-6976.2006.00038.x, PubMed 17064283
6. Aas FE, Winther-Larsen HC, Wolfgang M, Frye S, Løvold C, Roos N, van Putten JP, Koomey M (2006)
   Substitutions in the N-terminal alpha helical spine of Neisseria gonorrhoeae pilin affect Type IV pilus assembly, dynamics and associated functions
   Mol Microbiol, 63 (1), 69-85
   DOI 10.1111/j.1365-2958.2006.05482.x, PubMed 17140412

Publications 2005

1. Collins RF, Frye SA, Balasingham S, Ford RC, Tønjum T, Derrick JP (2005)
   Interaction with type IV pili induces structural changes in the bacterial outer membrane secretin PilQ
   J Biol Chem, 280 (19), 18923-30
   DOI 10.1074/jbc.M411603200, PubMed 15753075
2. Davidsen T, Bjørås M, Seeberg EC, Tønjum T (2005)
   Antimutator role of DNA glycosylase MutY in pathogenic Neisseria species
   J Bacteriol, 187 (8), 2801-9
   DOI 10.1128/JB.187.8.2801-2809.2005, PubMed 15805527

Publications 2004

1. Collins RF, Frye SA, Kitmitto A, Ford RC, Tønjum T, Derrick JP (2004)
   Structure of the Neisseria meningitidis outer membrane PilQ secretin complex at 12 A resolution
   J Biol Chem, 279 (38), 39750-6
   DOI 10.1074/jbc.M405971200, PubMed 15254043
2. Davidsen T, Rødland EA, Lagesen K, Seeberg E, Rognes T, Tønjum T (2004)
   Biased distribution of DNA uptake sequences towards genome maintenance genes
   Nucleic Acids Res, 32 (3), 1050-8
   DOI 10.1093/nar/gkh255, PubMed 14960717

Publications 2003

1. Collins RF, Ford RC, Kitmitto A, Olsen RO, Tønjum T, Derrick JP (2003)
   Three-dimensional structure of the Neisseria meningitidis secretin PilQ determined from negative-stain transmission electron microscopy
   J Bacteriol, 185 (8), 2611-7
   DOI 10.1128/JB.185.8.2611-2617.2003, PubMed 12670986