Publications 2024

Anthon CT, Pène F, Perner A, Azoulay E, Puxty K, Van De Louw A, Barratt-Due A, Chawla S, Castro P, Póvoa P, Coelho L, Metaxa V, Kochanek M, Liebregts T, Kander T, Hästbacka J, Andreasen JB, Péju E, Nielsen LB, Hvas CL, Dufranc E, Canet E, Lundqvist L, Wright CJ, Schmidt J et al. (2024)
Correction: Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)
Intensive Care Med, 50 (1), 154-155
DOI 10.1007/s00134-023-07291-6, PubMed 38078947

Anthon CT, Pène F, Perner A, Azoulay E, Puxty K, Van De Louw A, Chawla S, Castro P, Povoa P, Coelho L, Metaxa V, Kochanek M, Liebregts T, Kander T, Sivula M, Andreasen JB, Nielsen LB, Hvas CL, Dufranc E, Canet E, Wright CJ, Schmidt J, Uhel F, Missri L, Krag M et al. (2024)
Platelet transfusions in adult ICU patients with thrombocytopenia: A sub-study of the PLOT-ICU inception cohort study
Acta Anaesthesiol Scand, 68 (8), 1018-1030
DOI 10.1111/aas.14467, PubMed 38840310

Aslam TN, Barratt-Due A, Fiane AE, Friis CM, Hofsø K, Kåsine T, Romundstad L, Laake JH (2024)
Pregnant women with acute respiratory distress syndrome triggered by COVID-19
Tidsskr Nor Laegeforen, 144 (1)
DOI 10.4045/tidsskr.23.0615, PubMed 38258709

Barratt-Due A, Pettersen K, Børresdatter-Dahl T, Holter JC, Grønli RH, Dyrhol-Riise AM, Lerum TV, Holten AR, Tonby K, Trøseid M, Skjønsberg OH, Granerud BK, Heggelund L, Kildal AB, Schjalm C, Aaløkken TM, Aukrust P, Ueland T, Mollnes TE, Halvorsen B, NOR‐Solidarity study groupThe Norwegian SARS‐CoV‐2 study group (2024)
Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients
J Intern Med, 296 (1), 80-92
DOI 10.1111/joim.13783, PubMed 38539241

Fageräng B, Cyranka L, Schjalm C, McAdam KE, Larsen CS, Heinzelbecker J, Gedde-Dahl T, Würzner R, Espevik T, Tjønnfjord GE, Garred P, Barratt-Due A, Tvedt THA, Mollnes TE (2024)
The function of the complement system remains fully intact throughout the course of allogeneic stem cell transplantation
Front Immunol, 15, 1422370
DOI 10.3389/fimmu.2024.1422370, PubMed 38938578

Murphy SL, Balzer NR, Ranheim T, Sagen EL, Huse C, Bjerkeli V, Michelsen AE, Finbråten AK, Heggelund L, Dyrhol-Riise AM, Tveita A, Holten AR, Trøseid M, Ueland T, Ulas T, Aukrust P, Barratt-Due A, Halvorsen B, Dahl TB (2024)
Extracellular matrix remodelling pathway in peripheral blood mononuclear cells from severe COVID-19 patients: an explorative study
Front Immunol, 15, 1379570
DOI 10.3389/fimmu.2024.1379570, PubMed 38957465

Patrick-Brown TDJH, Barratt-Due A, Trøseid M, Dyrhol-Riise AM, Nezvalova-Henriksen K, Kåsine T, Aukrust P, Olsen IC, NOR Solidarity consortium (2024)
The effects of remdesivir on long-term symptoms in patients hospitalised for COVID-19: a pre-specified exploratory analysis
Commun Med (Lond), 4 (1), 231
DOI 10.1038/s43856-024-00650-4, PubMed 39533001

Publications 2023

Amstutz A, Speich B, Mentré F, Rueegg CS, Belhadi D, Assoumou L, Burdet C, Murthy S, Dodd LE, Wang Y, Tikkinen KAO, Ader F, Hites M, Bouscambert M, Trabaud MA, Fralick M, Lee TC, Pinto R, Barratt-Due A, Lund-Johansen F, Müller F, Nevalainen OPO, Cao B, Bonnett T, Griessbach A et al. (2023)
Effects of remdesivir in patients hospitalised with COVID-19: a systematic review and individual patient data meta-analysis of randomised controlled trials
Lancet Respir Med, 11 (5), 453-464
DOI 10.1016/S2213-2600(22)00528-8, PubMed 36828006

Anthon CT, Pène F, Perner A, Azoulay E, Puxty K, Van De Louw A, Barratt-Due A, Chawla S, Castro P, Póvoa P, Coelho L, Metaxa V, Kochanek M, Liebregts T, Kander T, Hästbacka J, Andreasen JB, Péju E, Nielsen LB, Hvas CL, Dufranc E, Canet E, Lundqvist L, Wright CJ, Schmidt J et al. (2023)
Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)
Intensive Care Med, 49 (11), 1327-1338
DOI 10.1007/s00134-023-07225-2, PubMed 37812225

Bakkehaug JP, Kåsine T, Romundstad L, Narum J, Laake JH, Svalebjørg M, Fiane AE, Hoel T, Thiara A, Pischke SE, Aasmundstad TA, Barratt-Due A (2023)
[Extracorporeal membrane oxygenation for acute respiratory distress syndrome in patients with COVID-19]
Tidsskr Nor Laegeforen, 143 (2)
DOI 10.4045/tidsskr.22.0545, PubMed 36718886

Laake JH, Aslam TN, Barratt-Due A, Løwhagen B, Pischke SE, Tønnessen TI, Wisløff-Aase K, Aasmundstad TA (2023)
[ARDS or acute respiratory failure syndrome?]
Tidsskr Nor Laegeforen, 143 (10)
DOI 10.4045/tidsskr.23.0402, PubMed 37376931

Murphy SL, Halvorsen B, Holter JC, Huse C, Tveita A, Trøseid M, Hoel H, Kildal AB, Holten AR, Lerum TV, Skjønsberg OH, Michelsen AE, Aaløkken TM, NOR-SOLIDARITY Consortium, The Norwegian SARS-CoV-2 study group investigators, Tonby K, Lind A, Dudman S, Granerud BK, Heggelund L, Bøe S, Dyrholt-Riise AM, Aukrust P, Barratt-Due A, Ueland T, Dahl TB (2023)
Circulating markers of extracellular matrix remodelling in severe COVID-19 patients
J Intern Med, 294 (6), 784-797
DOI 10.1111/joim.13725, PubMed 37718572

Tran TT, Vaage EB, Mehta A, Chopra A, Tietze L, Kolderup A, Anthi A, König M, Nygaard G, Lind A, Müller F, Nissen-Meyer LS, Magnus P, Trogstad L, Mjaaland S, Søraas A, Midtvedt K, Åsberg A, Barratt-Due A, Medhus AW, Høivik ML, Lundin K, Karlsen RF, Dahle R, Danielsson K et al. (2023)
Author Correction: Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 8 (1), 4
DOI 10.1038/s41541-023-00600-6, PubMed 36697432

Ueland T, Michelsen AE, Tveita AA, Kåsine T, Dahl TB, Finbråten AK, Holten AR, Skjønsberg OH, Mathiessen A, Henriksen KN, Trøseid M, Aaløkken TM, Halvorsen B, Dyrhol-Riise AM, Barratt-Due A, Aukrust P (2023)
Coagulopathy and adverse outcomes in hospitalized patients with COVID-19: results from the NOR-Solidarity trial
Res Pract Thromb Haemost, 8 (1), 102289
DOI 10.1016/j.rpth.2023.102289, PubMed 38292350

Publications 2022

Anthon CT, Pène F, Perner A, Azoulay E, Puxty K, Van De Louw A, Barratt-Due A, Chawla S, Castro P, Povoa P, Coelho L, Metaxa V, Munshi L, Kochanek M, Liebregts T, Kander T, Hästbacka J, Møller MH, Russell L, PLOT-ICU Investigators and the Nine-I Study Group (2022)
Platelet transfusions and thrombocytopenia in intensive care units: Protocol for an international inception cohort study (PLOT-ICU)
Acta Anaesthesiol Scand, 66 (9), 1146-1155
DOI 10.1111/aas.14124, PubMed 36054145

Burghi G, Metaxa V, Pickkers P, Soares M, Rello J, Bauer PR, van de Louw A, Taccone FS, Loeches IM, Schellongowski P, Rusinova K, Antonelli M, Kouatchet A, Barratt-Due A, Valkonen M, Pène F, Mokart D, Jaber S, Azoulay E, De Jong A, Efraim investigators and the Nine-I study group (2022)
End of life decisions in immunocompromised patients with acute respiratory failure
J Crit Care, 72, 154152
DOI 10.1016/j.jcrc.2022.154152, PubMed 36137351

Cavaillon JM, Artigas A, Barratt-Due A, Giamarellos-Bourboulis EJ, Gómez H, Hayem G, Vlaar APJ, Wiersinga WJ (2022)
SEVERE CORONAVIRUS DISEASE 2019: FROM PATHOGENESIS TO THERAPY
Shock, 59 (3S Suppl 1), 10-15
DOI 10.1097/SHK.0000000000001956, PubMed 36469709

Gregersen I, Ueland T, Holter JC, Olsen MB, Michelsen AE, Murphy SL, Tveita AA, Henriksen KN, Hoel H, Nordberg LB, Holten AR, Edvardsen T, Yang K, Heggelund L, Trøseid M, Müller F, Kildal AB, Dyrhol-Riise AM, Barratt-Due A, Dahl TB, Aukrust P, Halvorsen B, NOR-SOLIDARITY consortium, The Norwegian SARS-CoV-2 Study Group investigators (2022)
CXCL16 associates with adverse outcome and cardiac involvement in hospitalized patients with Covid-19
J Infect, 85 (6), 702-769
DOI 10.1016/j.jinf.2022.09.029, PubMed 36216188

Medeiros PMC, Schjalm C, Christiansen D, Sokolova M, Pischke SE, Würzner R, Mollnes TE, Barratt-Due A (2022)
Vitamin C, Hydrocortisone, and the Combination Thereof Significantly Inhibited Two of Nine Inflammatory Markers Induced by Escherichia Coli But Not by Staphylococcus Aureus - When Incubated in Human Whole Blood
Shock, 57 (1), 72-80
DOI 10.1097/SHK.0000000000001834, PubMed 34265830

Murphy SL, Halvorsen B, Barratt-Due A, Dyrhol-Riise AM, Aukrust P, Trøseid M, Dahl TB (2022)
Remdesivir modifies interferon response in hospitalized COVID-19 patients
J Infect, 85 (5), 573-607
DOI 10.1016/j.jinf.2022.07.021, PubMed 35914611

Tran TT, Vaage EB, Mehta A, Chopra A, Tietze L, Kolderup A, Anthi A, König M, Nygaard G, Lind A, Müller F, Nissen-Meyer LS, Magnus P, Trogstad L, Mjaaland S, Søraas A, Midtvedt K, Åsberg A, Barratt-Due A, Medhus AW, Høivik ML, Lundin K, Karlsen RF, Dahle R, Danielsson K et al. (2022)
Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 7 (1), 174
DOI 10.1038/s41541-022-00586-7, PubMed 36585405

Trøseid M, Dahl TB, Holter JC, Kildal AB, Murphy SL, Yang K, Quiles-Jiménez A, Heggelund L, Müller KE, Tveita A, Michelsen AE, Bøe S, Holten AR, Hoel H, Mathiessen A, Aaløkken TM, Fevang B, Granerud BK, Tonby K, Henriksen KN, Lerum TV, Müller F, Skjønsberg OH, Barratt-Due A, Dyrhol-Riise AM et al. (2022)
Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies
J Intern Med, 292 (5), 816-828
DOI 10.1111/joim.13549, PubMed 35982589

Tveita A, Murphy SL, Holter JC, Kildal AB, Michelsen AE, Lerum TV, Kaarbø M, Heggelund L, Holten AR, Finbråten AK, Müller KE, Mathiessen A, Bøe S, Fevang B, Granerud BK, Tonby K, Lind A, Dudman SG, Henriksen KN, Müller F, Skjønsberg OH, Trøseid M, Barratt-Due A, Dyrhol-Riise AM, Aukrust P et al. (2022)
High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19
J Infect Dis, 226 (12), 2150-2160
DOI 10.1093/infdis/jiac313, PubMed 35876699

Ueland T, Hausberg I, Mørtberg TV, Dahl TB, Lerum TV, Michelsen A, Ranheim T, Nezvalova Henriksen K, Dyrhol-Riise AM, Holme PA, Aaløkken TM, Skjønsberg OH, Barratt-Due A, Ahlén MT, Aukrust P, Halvorsen B (2022)
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology
Platelets, 33 (4), 640-644
DOI 10.1080/09537104.2022.2042238, PubMed 35225150

Vestad B, Ueland T, Lerum TV, Dahl TB, Holm K, Barratt-Due A, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Tonby K, Hoel H, Olsen IC, Henriksen KN, Tveita A, Manotheepan R, Haugli M, Eiken R, Berg Å, Halvorsen B, Lekva T, Ranheim T, Michelsen AE, Kildal AB, Johannessen A, Thoresen L et al. (2022)
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
J Intern Med, 291 (6), 801-812
DOI 10.1111/joim.13458, PubMed 35212063

Publications 2021

Barratt-Due A, Olsen IC, Nezvalova-Henriksen K, Kåsine T, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Kildal AB, Berg Å, Johannessen A, Heggelund L, Dahl TB, Skåra KH, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR, Olsen RB et al. (2021)
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
Ann Intern Med, 174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903

Bjørkto MH, Barratt-Due A, Nordøy I, Dörje C, Galteland E, Lind A, Hilli A, Aukrust P, Mjøen G (2021)
The use of eculizumab in Capnocytophaga canimorsus associated thrombotic microangiopathy: a case report
BMC Infect Dis, 21 (1), 137
DOI 10.1186/s12879-021-05789-2, PubMed 33526010

Blaise Pascal FN, Malisawa A, Barratt-Due A, Namboya F, Pollach G (2021)
General anaesthesia related mortality in a limited resource settings region: a retrospective study in two teaching hospitals of Butembo
BMC Anesthesiol, 21 (1), 60
DOI 10.1186/s12871-021-01280-2, PubMed 33622245

Blaise Pascal FN, Malisawa A, Barratt-Due A, Namboya F, Pollach G (2021)
Correction to: General anaesthesia related mortality in a limited resource settings region: a retrospective study in two teaching hospitals of Butembo
BMC Anesthesiol, 21 (1), 78
DOI 10.1186/s12871-021-01297-7, PubMed 33726661

Kåsine T, Dyrhol-Riise AM, Barratt-Due A, Kildal AB, Olsen IC, Nezvalova-Henriksen K, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Berg Å, Johannessen A, Heggelund L, Dahl TB, Halvorsen B, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR et al. (2021)
Neutrophil count predicts clinical outcome in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 291 (2), 241-243
DOI 10.1111/joim.13377, PubMed 34411368

Lerum TV, Maltzahn NN, Aukrust P, Trøseid M, Henriksen KN, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Haugli M, Blomberg B, Kittang BR, Johannessen A, Hannula R, Aballi S, Kildal AB, Eiken R, Dahl TB, Lund-Johansen F, Müller F, Rodriguez JR, Meltzer C, Einvik G, Ueland T, Olsen IC, NOR-SOLIDARITY Consortium et al. (2021)
Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9
Sci Rep, 11 (1), 23205
DOI 10.1038/s41598-021-02547-x, PubMed 34853380

Tangen J, Aukrust P, Barratt-Due A, Skulstad H, Edvardsen T (2021)
Reduced Cardiac Function by Echocardiography in a Minority of COVID-19 Patients 3 Months after Hospitalization
J Am Soc Echocardiogr, 35 (2), 243-244
DOI 10.1016/j.echo.2021.10.014, PubMed 34758386

Thomas AM, Chaban V, Pischke SE, Orrem HL, Bosnes V, Sunde K, Seljeflot I, Lundqvist C, Nakstad ER, Andersen GØ, Schjalm C, Mollnes TE, Barratt-Due A (2021)
Complement ratios C3bc/C3 and sC5b-9/C5 do not increase the sensitivity of detecting acute complement activation systemically
Mol Immunol, 141, 273-279
DOI 10.1016/j.molimm.2021.11.016, PubMed 34906905

Trøseid M, Hites M, Barratt-Due A, Ader F, Yazdanpanah Y (2021)
Assessing the evidence on remdesivir
Lancet Infect Dis, 21 (12), 1630-1631
DOI 10.1016/S1473-3099(21)00695-2, PubMed 34838222

Van de Louw A, Rello J, Martin-Loeches I, Mokart D, Metaxa V, Benoit D, Barratt-Due A, Soares M, Pickkers P, Antonelli M, Demoule A, Schellongowski P, Kouatchet A, Mehta S, Balik M, Bauer PR, Lemiale V, Walter V, Azoulay E, EFRAIM investigators and the Nine-I study group (2021)
Bacteremia in critically ill immunocompromised patients with acute hypoxic respiratory failure: A post-hoc analysis of a prospective multicenter multinational cohort
J Crit Care, 64, 114-119
DOI 10.1016/j.jcrc.2021.03.014, PubMed 33872917

Aamodt AH, Høgestøl EA, Popperud TH, Holter JC, Dyrhol-Riise AM, Tonby K, Stiksrud B, Quist-Paulsen E, Berge T, Barratt-Due A, Aukrust P, Heggelund L, Blennow K, Zetterberg H, Harbo HF (2021)
Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19
J Neurol, 268 (10), 3574-3583
DOI 10.1007/s00415-021-10517-6, PubMed 33743046

Publications 2020

Azoulay E, Bauer PR, Mariotte E, Russell L, Knoebl P, Martin-Loeches I, Pène F, Puxty K, Povoa P, Barratt-Due A, Garnacho-Montero J, Wendon J, Munshi L, Benoit D, von Bergwelt-Baildon M, Maggiorini M, Coppo P, Cataland S, Veyradier A, Van de Louw A, Nine-i Investigators (2020)
Correction to: Expert statement on the ICU management of patients with thrombotic thrombocytopenic purpura
Intensive Care Med, 46 (3), 570-571
DOI 10.1007/s00134-019-05904-7, PubMed 31965263

Blaise Pascal FN, Musavuli PK, Ketha JK, Sikakulya FK, Barratt-Due A, Castner T, Pollach G (2020)
Practice of standard monitoring during anaesthesia in hospitals of North Kivu: a survey of health facilities of the health antenna of Butembo
BMC Health Serv Res, 20 (1), 262
DOI 10.1186/s12913-020-05076-x, PubMed 32228583

Demoule A, Antonelli M, Schellongowski P, Pickkers P, Soares M, Meyhoff T, Rello J, Bauer PR, van de Louw A, Lemiale V, Grimaldi D, Martin-Loeches I, Balik M, Mehta S, Kouatchet A, Barratt-Due A, Valkonen M, Reignier J, Metaxa V, Moreau AS, Burghi G, Mokart D, Mayaux J, Darmon M, Azoulay E et al. (2020)
Respiratory Mechanics and Outcomes in Immunocompromised Patients With ARDS: A Secondary Analysis of the EFRAIM Study
Chest, 158 (5), 1947-1957
DOI 10.1016/j.chest.2020.05.602, PubMed 32569634

Holter JC, Pischke SE, de Boer E, Lind A, Jenum S, Holten AR, Tonby K, Barratt-Due A, Sokolova M, Schjalm C, Chaban V, Kolderup A, Tran T, Tollefsrud Gjølberg T, Skeie LG, Hesstvedt L, Ormåsen V, Fevang B, Austad C, Müller KE, Fladeby C, Holberg-Petersen M, Halvorsen B, Müller F, Aukrust P et al. (2020)
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538

Kayambankadzanja RK, Lihaka M, Barratt-Due A, Kachingwe M, Kumwenda W, Lester R, Bilima S, Eriksen J, Baker T (2020)
The use of antibiotics in the intensive care unit of a tertiary hospital in Malawi
BMC Infect Dis, 20 (1), 776
DOI 10.1186/s12879-020-05505-6, PubMed 33076857

Laake JH, Aasmundstad TA, Kåsine T, Pischke SE, Barratt-Due A (2020)
[COVID-19: evidence, eminence, or experience- based treatment?]
Tidsskr Nor Laegeforen, 140 (12)
DOI 10.4045/tidsskr.20.0649, PubMed 32900165

Martin-Loeches I, Darmon M, Demoule A, Antonelli M, Schellongowski P, Pickkers P, Soares M, Rello J, Bauer P, van de Louw A, Lemiale V, Grimaldi D, Balik M, Mehta S, Kouatchet A, Barratt-Due A, Valkonen M, Reignier J, Metaxa V, Moreau AS, Burghi G, Mokart D, Azoulay E, Efraim investigators and the Nine-I study group (2020)
ICU-acquired pneumonia in immunosuppressed patients with acute hypoxemic respiratory failure: A post-hoc analysis of a prospective international cohort study
J Crit Care, 63, 243-245
DOI 10.1016/j.jcrc.2020.09.027, PubMed 33012580

Messika J, Darmon M, Mal H, Pickkers P, Soares M, Canet E, Rello J, Bauer PR, van de Louw A, Lemiale V, Taccone FS, Loeches IM, Schellongowski P, Mehta S, Antonelli M, Kouatchet A, Barratt-Due A, Valkonen M, Bruneel F, Pène F, Metaxa V, Moreau AS, Burghi G, Montini L, Barbier F et al. (2020)
Etiologies and Outcomes of Acute Respiratory Failure in Solid Organ Transplant Recipients: Insight Into the EFRAIM Multicenter Cohort
Transplant Proc, 52 (10), 2980-2987
DOI 10.1016/j.transproceed.2020.02.170, PubMed 32499142

Mokart D, Darmon M, Schellongowski P, Pickkers P, Soares M, Rello J, Bauer PR, van de Louw A, Lemiale V, Taccone FS, Martin-Loeches I, Salluh J, Rusinova K, Mehta S, Antonelli M, Kouatchet A, Barratt-Due A, Valkonen M, Landburg PP, Bukan RB, Pène F, Metaxa V, Burghi G, Saillard C, Nielsen LB et al. (2020)
Acute respiratory failure in immunocompromised patients: outcome and clinical features according to neutropenia status
Ann Intensive Care, 10 (1), 146
DOI 10.1186/s13613-020-00764-7, PubMed 33090310

Munshi L, Darmon M, Soares M, Pickkers P, Bauer P, Meert AP, Martin-Loeches I, Staudinger T, Pene F, Antonelli M, Barratt-Due A, Demoule A, Metaxa V, Lemiale V, Taccone F, Mokart D, Azoulay E, Mehta S, EFRAIM Investigators (2020)
Acute Respiratory Failure Outcomes in Patients with Hematologic Malignancies and Hematopoietic Cell Transplant: A Secondary Analysis of the EFRAIM Study
Transplant Cell Ther, 27 (1), 78.e1-78.e6
DOI 10.1016/j.bbmt.2020.09.035, PubMed 33011289

Pischke SE, Hødnebø S, Wester T, Haugaa H, Kvernebo K, Barratt-Due A, Tønnessen TI (2020)
Intraperitoneal microdialysis detects intestinal leakage earlier than hemodynamic surveillance and systemic inflammation in a pig model
Scand J Gastroenterol, 56 (2), 219-227
DOI 10.1080/00365521.2020.1863459, PubMed 33356757

Ueland T, Heggelund L, Lind A, Holten AR, Tonby K, Michelsen AE, Jenum S, Jørgensen MJ, Barratt-Due A, Skeie LG, Nordøy I, Aanensen Fraz MS, Quist-Paulsen E E, Pischke SE, Johal SK, Hesstvedt L, Bogen M, Fevang B, Halvorsen B, Müller F, Bekken GK, Mollnes TE, Dudman S, Aukrust P, Dyrhol-Riise AM et al. (2020)
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol, 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109

WHO Solidarity Trial Consortium, Pan H, Peto R, Henao-Restrepo AM, Preziosi MP, Sathiyamoorthy V, Abdool Karim Q, Alejandria MM, Hernández García C, Kieny MP, Malekzadeh R, Murthy S, Reddy KS, Roses Periago M, Abi Hanna P, Ader F, Al-Bader AM, Alhasawi A, Allum E, Alotaibi A, Alvarez-Moreno CA, Appadoo S, Asiri A, Aukrust P, Barratt-Due A et al. (2020)
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results
N Engl J Med, 384 (6), 497-511
DOI 10.1056/NEJMoa2023184, PubMed 33264556

Aamodt AH, Flinstad Harbo H, Eldøen G, Barratt-Due A, Aukrust P (2020)
How does COVID-19 affect the brain?
Tidsskr Nor Laegeforen, 140 (10)
DOI 10.4045/tidsskr.20.0444, PubMed 32602331

Publications 2019

Azoulay E, Bauer PR, Mariotte E, Russell L, Knoebl P, Martin-Loeches I, Pène F, Puxty K, Povoa P, Barratt-Due A, Garnacho-Montero J, Wendon J, Munshi L, Benoit D, von Bergwelt-Baildon M, Maggiorini M, Coppo P, Cataland S, Veyradier A, Van de Louw A, Nine-i Investigators (2019)
Expert statement on the ICU management of patients with thrombotic thrombocytopenic purpura
Intensive Care Med, 45 (11), 1518-1539
DOI 10.1007/s00134-019-05736-5, PubMed 31588978

Bauer PR, Chevret S, Yadav H, Mehta S, Pickkers P, Bukan RB, Rello J, van de Louw A, Klouche K, Meert AP, Martin-Loeches I, Marsh B, Socias Crespi L, Moreno-Gonzalez G, Buchtele N, Amrein K, Balik M, Antonelli M, Nyunga M, Barratt-Due A, Bergmans DCJJ, Spoelstra-de Man AME, Kuitunen A, Wallet F, Seguin A et al. (2019)
Diagnosis and outcome of acute respiratory failure in immunocompromised patients after bronchoscopy
Eur Respir J, 54 (1)
DOI 10.1183/13993003.02442-2018, PubMed 31109985

Martin-Loeches I, Lemiale V, Geoghegan P, McMahon MA, Pickkers P, Soares M, Perner A, Meyhoff TS, Bukan RB, Rello J, Bauer PR, van de Louw A, Taccone FS, Salluh J, Hemelaar P, Schellongowski P, Rusinova K, Terzi N, Mehta S, Antonelli M, Kouatchet A, Klepstad P, Valkonen M, Landburg PP, Barratt-Due A et al. (2019)
Influenza and associated co-infections in critically ill immunosuppressed patients
Crit Care, 23 (1), 152
DOI 10.1186/s13054-019-2425-6, PubMed 31046842

Thomas AM, Gerogianni A, McAdam MB, Fløisand Y, Lau C, Espevik T, Nilsson PH, Mollnes TE, Barratt-Due A (2019)
Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood
J Immunol, 203 (6), 1571-1578
DOI 10.4049/jimmunol.1900047, PubMed 31413105

Thorgersen EB, Barratt-Due A, Haugaa H, Harboe M, Pischke SE, Nilsson PH, Mollnes TE (2019)
The Role of Complement in Liver Injury, Regeneration, and Transplantation
Hepatology, 70 (2), 725-736
DOI 10.1002/hep.30508, PubMed 30653682

Publications 2018

Buanes EA, Barratt-Due A, Kvale R, Leistad L, Konstante R (2018)
Important to distinguish intermediate from intensive care patients
Tidsskr. Nor. Laegeforen., 138 (11), 993-994

Buanes EA, Barratt-Due A, Kvåle R, Leistad L, Konstante R (2018)
[Not Available]
Tidsskr Nor Laegeforen, 138 (11)
DOI 10.4045/tidsskr.18.0477, PubMed 29947193

Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GØ, Barratt-Due A, Mollnes TE (2018)
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
ESC Heart Fail, 5 (3), 292-301
DOI 10.1002/ehf2.12266, PubMed 29424484

Orrem HL, Nilsson PH, Pischke SE, Kleveland O, Yndestad A, Ekholt K, Damås JK, Espevik T, Bendz B, Halvorsen B, Gregersen I, Wiseth R, Andersen GØ, Ueland T, Gullestad L, Aukrust P, Barratt-Due A, Mollnes TE (2018)
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440

Thomas AM, Schjalm C, Nilsson PH, Lindenskov PHH, Rørtveit R, Solberg R, Saugstad OD, Berglund MM, Strömberg P, Lau C, Espevik T, Jansen JH, Castellheim A, Mollnes TE, Barratt-Due A (2018)
Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome
Neonatology, 113 (4), 322-330
DOI 10.1159/000486542, PubMed 29486477

Publications 2017

Azoulay E, Pickkers P, Soares M, Perner A, Rello J, Bauer PR, van de Louw A, Hemelaar P, Lemiale V, Taccone FS, Martin Loeches I, Meyhoff TS, Salluh J, Schellongowski P, Rusinova K, Terzi N, Mehta S, Antonelli M, Kouatchet A, Barratt-Due A, Valkonen M, Landburg PP, Bruneel F, Bukan RB, Pène F et al. (2017)
Acute hypoxemic respiratory failure in immunocompromised patients: the Efraim multinational prospective cohort study
Intensive Care Med, 43 (12), 1808-1819
DOI 10.1007/s00134-017-4947-1, PubMed 28948369

Gustavsen A, Skattum L, Bergseth G, Lorentzen B, Floisand Y, Bosnes V, Mollnes TE, Barratt-Due A (2017)
Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome: A case report
Medicine (Baltimore), 96 (11), e6338
DOI 10.1097/MD.0000000000006338, PubMed 28296762

Nilsson PH, Thomas AM, Bergseth G, Gustavsen A, Volokhina EB, van den Heuvel LP, Barratt-Due A, Mollnes TE (2017)
Eculizumab-C5 complexes express a C5a neoepitope in vivo: Consequences for interpretation of patient complement analyses
Mol Immunol, 89, 111-114
DOI 10.1016/j.molimm.2017.05.021, PubMed 28610663

Pischke SE, Gustavsen A, Orrem HL, Egge KH, Courivaud F, Fontenelle H, Despont A, Bongoni AK, Rieben R, Tønnessen TI, Nunn MA, Scott H, Skulstad H, Barratt-Due A, Mollnes TE (2017)
Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function
Basic Res Cardiol, 112 (3), 20
DOI 10.1007/s00395-017-0610-9, PubMed 28258298

Ricklin D, Barratt-Due A, Mollnes TE (2017)
Complement in clinical medicine: Clinical trials, case reports and therapy monitoring
Mol Immunol, 89, 10-21
DOI 10.1016/j.molimm.2017.05.013, PubMed 28576323

Publications 2016

Barratt-Due A, Fløisand Y, Orrem HL, Kvam AK, Holme PA, Bergseth G, Tjønnfjord GE, Mollnes TE (2016)
Complement activation is a crucial pathogenic factor in catastrophic antiphospholipid syndrome
Rheumatology (Oxford), 55 (7), 1337-9
DOI 10.1093/rheumatology/kew040, PubMed 27105662

Barratt-Due A, Pischke SE, Nilsson PH, Espevik T, Mollnes TE (2016)
Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets
J Leukoc Biol, 101 (1), 193-204
DOI 10.1189/jlb.3VMR0316-132R, PubMed 27581539

Publications 2015

Egge KH, Barratt-Due A, Nymo S, Lindstad JK, Pharo A, Lau C, Espevik T, Thorgersen EB, Mollnes TE (2015)
The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load
Clin Exp Immunol, 181 (3), 457-67
DOI 10.1111/cei.12645, PubMed 25907631

Egge KH, Thorgersen EB, Pischke SE, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn MA, Barratt-Due A, Mollnes TE (2015)
Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14
Immunobiology, 220 (8), 999-1005
DOI 10.1016/j.imbio.2015.04.002, PubMed 25956456

Skjeflo EW, Sagatun C, Dybwik K, Aam S, Urving SH, Nunn MA, Fure H, Lau C, Brekke OL, Huber-Lang M, Espevik T, Barratt-Due A, Nielsen EW, Mollnes TE (2015)
Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis
Crit Care, 19, 415
DOI 10.1186/s13054-015-1129-9, PubMed 26612199

Publications 2014

Huber-Lang M, Barratt-Due A, Pischke SE, Sandanger Ø, Nilsson PH, Nunn MA, Denk S, Gaus W, Espevik T, Mollnes TE (2014)
Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice
J Immunol, 192 (11), 5324-31
DOI 10.4049/jimmunol.1400341, PubMed 24790148

Publications 2013

Barratt-Due A, Thorgersen EB, Egge K, Pischke S, Sokolov A, Hellerud BC, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn M, Scott H, Mollnes TE (2013)
Combined inhibition of complement C5 and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis
J Immunol, 191 (2), 819-27
DOI 10.4049/jimmunol.1201909, PubMed 23761634

Egge KH, Thorgersen EB, Lindstad JK, Pharo A, Lambris JD, Barratt-Due A, Mollnes TE (2013)
Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood
Innate Immun, 20 (1), 68-77
DOI 10.1177/1753425913482993, PubMed 23669326

Lau C, Gunnarsen KS, Høydahl LS, Andersen JT, Berntzen G, Pharo A, Lindstad JK, Ludviksen JK, Brekke OL, Barratt-Due A, Nielsen EW, Stokes CR, Espevik T, Sandlie I, Mollnes TE (2013)
Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation
J Immunol, 191 (9), 4769-77
DOI 10.4049/jimmunol.1301653, PubMed 24062486

Thorgersen EB, Pischke SE, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Hellerud BC, Mollnes TE (2013)
Systemic CD14 inhibition attenuates organ inflammation in porcine Escherichia coli sepsis
Infect Immun, 81 (9), 3173-81
DOI 10.1128/IAI.00390-13, PubMed 23774598

Publications 2012

Barratt-Due A, Pischke SE, Brekke OL, Thorgersen EB, Nielsen EW, Espevik T, Huber-Lang M, Mollnes TE (2012)
Bride and groom in systemic inflammation--the bells ring for complement and Toll in cooperation
Immunobiology, 217 (11), 1047-56
DOI 10.1016/j.imbio.2012.07.019, PubMed 22964230

Barratt-Due A, Sokolov A, Gustavsen A, Hellerud BC, Egge K, Pischke SE, Lindstad JK, Pharo A, Castellheim A, Thorgersen EB, Mollnes TE (2012)
Polyvalent immunoglobulin significantly attenuated the formation of IL-1β in Escherichia coli-induced sepsis in pigs
Immunobiology, 218 (5), 683-9
DOI 10.1016/j.imbio.2012.08.268, PubMed 22947599

Publications 2011

Barratt-Due A, Johansen HT, Sokolov A, Thorgersen EB, Hellerud BC, Reubsaet JL, Seip KF, Tønnessen TI, Lindstad JK, Pharo A, Castellheim A, Mollnes TE, Nielsen EW (2011)
The role of bradykinin and the effect of the bradykinin receptor antagonist icatibant in porcine sepsis
Shock, 36 (5), 517-23
DOI 10.1097/SHK.0b013e3182336a34, PubMed 21921836

Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Lissina O, Lambris JD, Nunn MA, Mollnes TE (2011)
Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans
J Immunol, 187 (9), 4913-9
DOI 10.4049/jimmunol.1101000, PubMed 21964028

Publications 2010

Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Brekke OL, Christiansen D, Lambris JD, Mollnes TE (2010)
Selective inhibition of TNF-alpha or IL-1 beta does not affect E. coli-induced inflammation in human whole blood
Mol Immunol, 47 (9), 1774-82
DOI 10.1016/j.molimm.2010.02.026, PubMed 20334922

Wester T, Häggblad E, Awan ZA, Barratt-Due A, Kvernebo M, Halvorsen PS, Mollnes TE, Kvernebo K (2010)
Assessments of skin and tongue microcirculation reveals major changes in porcine sepsis
Clin Physiol Funct Imaging, 31 (2), 151-8
DOI 10.1111/j.1475-097X.2010.00994.x, PubMed 21087397

Publications 2009

Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tønnessen TI, Johansen HT, Castellheim A, Mollnes TE (2009)
CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs
FASEB J, 24 (3), 712-22
DOI 10.1096/fj.09-140798, PubMed 19841036

Publications 2008

Barratt-Due A (2008)
[Better mother after a painful labor?]
Tidsskr Nor Laegeforen, 128 (8), 945; author reply 945
PubMed 18431426

Publications 2005

Barratt-Due A, Hagen I, Dahl V (2005)
[Obstetric analgesia in Norwegian hospitals]
Tidsskr Nor Laegeforen, 125 (18), 2504-6
PubMed 16186873