Publications Anita Langerød
Publications by Anita Langerød
55 publications found
Publications 2025
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 Cost-effectiveness of Prosigna for Adjuvant Treatment Decisions in Early Breast Cancer: Healthcare Sector and Societal Perspectives
 Clin Breast Cancer, 25 (6), e721-e730
 DOI 10.1016/j.clbc.2025.04.011, PubMed 40348620
Publications 2024
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 Impact of Prosigna test on adjuvant treatment decision in lymph node-negative early breast cancer-a prospective national multicentre study (EMIT-1)
 ESMO Open, 9 (6), 103475
 DOI 10.1016/j.esmoop.2024.103475, PubMed 38838499
Publications 2023
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 Obesity-associated changes in molecular biology of primary breast cancer
 Nat Commun, 14 (1), 4418
 DOI 10.1038/s41467-023-39996-z, PubMed 37479706
Publications 2022
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 Cis-regulatory mutations associate with transcriptional and post-transcriptional deregulation of gene regulatory programs in cancers
 Nucleic Acids Res, 50 (21), 12131-12148
 DOI 10.1093/nar/gkac1143, PubMed 36477895
Publications 2020
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 DNA copy number motifs are strong and independent predictors of survival in breast cancer
 Commun Biol, 3 (1), 153
 DOI 10.1038/s42003-020-0884-6, PubMed 32242091
Publications 2019
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 Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences
 Nature, 566 (7742), E1
 DOI 10.1038/s41586-019-0883-2, PubMed 30659290
Publications 2017
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 Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice
 Cancer Res, 77 (6), 1250-1260
 DOI 10.1158/0008-5472.CAN-16-2179, PubMed 28254861
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 Assessment of TP53 Polymorphisms and MDM2 SNP309 in Premenopausal Breast Cancer Risk
 Hum Mutat, 38 (3), 265-268
 DOI 10.1002/humu.23154, PubMed 27957778
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 TP53 Mutations in Breast and Ovarian Cancer
 Cold Spring Harb Perspect Med, 7 (1)
 DOI 10.1101/cshperspect.a026252, PubMed 27815305
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 The Longitudinal Transcriptional Response to Neoadjuvant Chemotherapy with and without Bevacizumab in Breast Cancer
 Clin Cancer Res, 23 (16), 4662-4670
 DOI 10.1158/1078-0432.CCR-17-0160, PubMed 28487444
Publications 2016
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 Landscape of somatic mutations in 560 breast cancer whole-genome sequences
 Nature, 534 (7605), 47-54
 DOI 10.1038/nature17676, PubMed 27135926
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 Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer
 Cell Rep, 16 (7), 2032-46
 DOI 10.1016/j.celrep.2016.07.028, PubMed 27498871
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 Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration
 Nat Commun, 7, 12910
 DOI 10.1038/ncomms12910, PubMed 27666519
Publications 2015
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 The Sub-Cellular Localization of WRAP53 Has Prognostic Impact in Breast Cancer
 PLoS One, 10 (10), e0139965
 DOI 10.1371/journal.pone.0139965, PubMed 26460974
Publications 2014
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 Lymphocyte Invasion in IC10/Basal-Like Breast Tumors Is Associated with Wild-Type TP53
 Mol Cancer Res, 13 (3), 493-501
 DOI 10.1158/1541-7786.MCR-14-0387, PubMed 25351767
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 TP53 mutation spectrum in breast cancer is subtype specific and has distinct prognostic relevance
 Clin Cancer Res, 20 (13), 3569-80
 DOI 10.1158/1078-0432.CCR-13-2943, PubMed 24803582
Publications 2013
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 AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
 Breast Cancer Res Treat, 141 (3), 397-408
 DOI 10.1007/s10549-013-2702-z, PubMed 24091768
Publications 2012
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 The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
 Nature, 486 (7403), 346-52
 DOI 10.1038/nature10983, PubMed 22522925
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 Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
 Cell, 148 (1-2), 244-58
 DOI 10.1016/j.cell.2011.12.017, PubMed 22265415
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 Functional characterization of the 19q12 amplicon in grade III breast cancers
 Breast Cancer Res, 14 (2), R53
 DOI 10.1186/bcr3154, PubMed 22433433
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 Mutational processes molding the genomes of 21 breast cancers
 Cell, 149 (5), 979-93
 DOI 10.1016/j.cell.2012.04.024, PubMed 22608084
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 The life history of 21 breast cancers
 Cell, 149 (5), 994-1007
 DOI 10.1016/j.cell.2012.04.023, PubMed 22608083
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 AZGP1 and SPDEF mRNA expression differentiates breast carcinoma from ovarian serous carcinoma
 Virchows Arch, 462 (2), 163-73
 DOI 10.1007/s00428-012-1347-3, PubMed 23242172
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 The landscape of cancer genes and mutational processes in breast cancer
 Nature, 486 (7403), 400-4
 DOI 10.1038/nature11017, PubMed 22722201
Publications 2011
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 Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
 Nat Genet, 43 (7), 621-9
 DOI 10.1038/ng.848, PubMed 21642992
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 Association of the germline TP53 R72P and MDM2 SNP309 variants with breast cancer survival in specific breast tumor subgroups
 Breast Cancer Res Treat, 130 (2), 599-608
 DOI 10.1007/s10549-011-1615-y, PubMed 21667122
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 Combining gene signatures improves prediction of breast cancer survival
 PLoS One, 6 (3), e17845
 DOI 10.1371/journal.pone.0017845, PubMed 21423775
Publications 2010
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 p53-Dependent repression of focal adhesion kinase in response to estradiol in breast cancer cell-lines
 Cancer Lett, 300 (2), 215-24
 DOI 10.1016/j.canlet.2010.10.008, PubMed 21071137
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 Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment
 Am J Pathol, 176 (3), 1229-40
 DOI 10.2353/ajpath.2010.090648, PubMed 20133812
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 BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations
 BMC Cancer, 10, 654
 DOI 10.1186/1471-2407-10-654, PubMed 21118481
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 Genomic architecture characterizes tumor progression paths and fate in breast cancer patients
 Sci Transl Med, 2 (38), 38ra47
 DOI 10.1126/scitranslmed.3000611, PubMed 20592421
Publications 2009
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 Focal amplification and oncogene dependency of GAB2 in breast cancer
 Oncogene, 29 (5), 774-9
 DOI 10.1038/onc.2009.364, PubMed 19881546
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 Somatic mutation databases as tools for molecular epidemiology and molecular pathology of cancer: proposed guidelines for improving data collection, distribution, and integration
 Hum Mutat, 30 (3), 275-82
 DOI 10.1002/humu.20832, PubMed 19006239
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 Complex landscapes of somatic rearrangement in human breast cancer genomes
 Nature, 462 (7276), 1005-10
 DOI 10.1038/nature08645, PubMed 20033038
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 Full sequencing of TP53 identifies identical mutations within in situ and invasive components in breast cancer suggesting clonal evolution
 Mol Oncol, 3 (3), 214-9
 DOI 10.1016/j.molonc.2009.03.001, PubMed 19403344
Publications 2008
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 CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer
 Mol Oncol, 2 (4), 327-39
 DOI 10.1016/j.molonc.2008.09.004, PubMed 19383354
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 Human papillomavirus DNA and e6/e7 mRNA status in relation to survival of patients treated for cervical squamous cell carcinoma
 Open Virol J, 2, 74-81
 DOI 10.2174/1874357900802010074, PubMed 19440467
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 EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer
 Breast Cancer Res, 10 (6), R109
 DOI 10.1186/bcr2214, PubMed 19099573
Publications 2007
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 Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas
 Breast Cancer Res, 9 (1), R5
 DOI 10.1186/bcr1637, PubMed 17224074
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 Common genetic variation in TP53 and its flanking genes, WDR79 and ATP1B2, and susceptibility to breast cancer
 Int J Cancer, 121 (11), 2532-8
 DOI 10.1002/ijc.22985, PubMed 17683073
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 Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status
 Cancer Epidemiol Biomarkers Prev, 16 (11), 2269-75
 DOI 10.1158/1055-9965.EPI-07-0449, PubMed 18006915
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 Discovery and validation of breast cancer subtypes (vol 8, pg 101, 2007)
 BMC Genomics, 8, 101
 DOI 10.1186/1471-2164-8-101
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 TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer
 Breast Cancer Res, 9 (3), R30
 DOI 10.1186/bcr1675, PubMed 17504517
Publications 2006
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 Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parameters
 Mol Cancer, 5, 47
 DOI 10.1186/1476-4598-5-47, PubMed 17054774
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 Discovery and validation of breast cancer subtypes
 BMC Genomics, 7, 231
 DOI 10.1186/1471-2164-7-231, PubMed 16965636
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 The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer
 Clin Cancer Res, 12 (4), 1157-67
 DOI 10.1158/1078-0432.CCR-05-1029, PubMed 16489069
Publications 2005
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 Gene expression profiling of breast cancer in relation to estrogen receptor status and estrogen-metabolizing enzymes: clinical implications
 Clin Cancer Res, 11 (2 Pt 2), 878s-83s
 PubMed 15701881
Publications 2004
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 Mutation of GATA3 in human breast tumors
 Oncogene, 23 (46), 7669-78
 DOI 10.1038/sj.onc.1207966, PubMed 15361840
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 Different gene expression patterns in invasive lobular and ductal carcinomas of the breast
 Mol Biol Cell, 15 (6), 2523-36
 DOI 10.1091/mbc.e03-11-0786, PubMed 15034139
Publications 2003
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 Overexpression of cyclin A overrides the effect of p53 alterations in breast cancer patients with long follow-up time
 Breast Cancer Res Treat, 80 (2), 199-206
 DOI 10.1023/A:1024527220362, PubMed 12908823
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 BUB1 infrequently mutated in human breast carcinomas
 Hum Mutat, 22 (5), 420
 DOI 10.1002/humu.9194, PubMed 14517964
Publications 2002
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 High frequency of skewed X inactivation in young breast cancer patients
 J Med Genet, 39 (1), 30-3
 DOI 10.1136/jmg.39.1.30, PubMed 11826021
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 The TP53 codon 72 polymorphism may affect the function of TP53 mutations in breast carcinomas but not in colorectal carcinomas
 Cancer Epidemiol Biomarkers Prev, 11 (12), 1684-8
 PubMed 12496062
Publications 1999
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 BRCA1 screening in patients with a family history of breast or ovarian cancer
 Genet Test, 3 (2), 223-6
 DOI 10.1089/gte.1999.3.223, PubMed 10464672
Publications 1998
- 
 p53 polymorphism and risk of cervical cancer
 Nature, 396 (6711), 530-1; author reply 532
 DOI 10.1038/25034, PubMed 9859987
