Publications 2024

Combriat T, Olsen PA, Låstad SB, Malthe-Sørenssen A, Krauss S, Dysthe DK (2024)
Acoustic Wave-Induced Stroboscopic Optical Mechanotyping of Adherent Cells
Adv Sci (Weinh), 11 (16), e2307929
DOI 10.1002/advs.202307929, PubMed 38417124

Wang C, Abadpour S, Aizenshtadt A, Dalmao-Fernandez A, Høyem M, Wilhelmsen I, Stokowiec J, Olsen PA, Krauss S, Chera S, Ghila L, Ræder H, Scholz H (2024)
Cell identity dynamics and insight into insulin secretagogues when employing stem cell-derived islets for disease modeling
Front Bioeng Biotechnol, 12, 1392575
DOI 10.3389/fbioe.2024.1392575, PubMed 38933536

Wang C, Abadpour S, Olsen PA, Wang D, Stokowiec J, Chera S, Ghila L, Ræder H, Krauss S, Aizenshtadt A, Scholz H (2024)
Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells
Transpl Int, 37, 11900
DOI 10.3389/ti.2024.11900, PubMed 38304198

Wilhelmsen I, Combriat T, Dalmao-Fernandez A, Stokowiec J, Wang C, Olsen PA, Wik JA, Boichuk Y, Aizenshtadt A, Krauss S (2024)
The effects of TGF-β-induced activation and starvation of vitamin A and palmitic acid on human stem cell-derived hepatic stellate cells
Stem Cell Res Ther, 15 (1), 223
DOI 10.1186/s13287-024-03852-8, PubMed 39044210

Publications 2023

Kwak D, Combriat T, Jensenius AR, Olsen PA (2023)
Characterization of Mechanical and Cellular Effects of Rhythmic Vertical Vibrations on Adherent Cell Cultures
Bioengineering (Basel), 10 (7)
DOI 10.3390/bioengineering10070811, PubMed 37508838

Publications 2022

Brinch SA, Amundsen-Isaksen E, Espada S, Hammarström C, Aizenshtadt A, Olsen PA, Holmen L, Høyem M, Scholz H, Grødeland G, Sowa ST, Galera-Prat A, Lehtiö L, Meerts IATM, Leenders RGG, Wegert A, Krauss S, Waaler J (2022)
The Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models
Cancer Res Commun, 2 (4), 233-245
DOI 10.1158/2767-9764.CRC-22-0027, PubMed 36873622

Kwak D, Olsen PA, Danielsen A, Jensenius AR (2022)
A trio of biological rhythms and their relevance in rhythmic mechanical stimulation of cell cultures
Front Psychol, 13, 867191
DOI 10.3389/fpsyg.2022.867191, PubMed 35967633

Publications 2021

Mygland L, Brinch SA, Strand MF, Olsen PA, Aizenshtadt A, Lund K, Solberg NT, Lycke M, Thorvaldsen TE, Espada S, Misaghian D, Page CM, Agafonov O, Nygård S, Chi NW, Lin E, Tan J, Yu Y, Costa M, Krauss S, Waaler J (2021)
Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
iScience, 24 (7), 102807
DOI 10.1016/j.isci.2021.102807, PubMed 34337362

Olsen PA, Krauss S (2021)
The Adenoviral E1B-55k Protein Present in HEK293 Cells Mediates Abnormal Accumulation of Key WNT Signaling Proteins in Large Cytoplasmic Aggregates
Genes (Basel), 12 (12)
DOI 10.3390/genes12121920, PubMed 34946869

Publications 2020

Abadpour S, Aizenshtadt A, Olsen PA, Shoji K, Wilson SR, Krauss S, Scholz H (2020)
Pancreas-on-a-Chip Technology for Transplantation Applications
Curr Diab Rep, 20 (12), 72
DOI 10.1007/s11892-020-01357-1, PubMed 33206261

Waaler J, Mygland L, Tveita A, Strand MF, Solberg NT, Olsen PA, Aizenshtadt A, Fauskanger M, Lund K, Brinch SA, Lycke M, Dybing E, Nygaard V, Bøe SL, Heintz KM, Hovig E, Hammarström C, Corthay A, Krauss S (2020)
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
Commun Biol, 3 (1), 196
DOI 10.1038/s42003-020-0916-2, PubMed 32332858

Publications 2019

Solberg NT, Melheim M, Strand MF, Olsen PA, Krauss S (2019)
MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition
Cancers (Basel), 11 (2)
DOI 10.3390/cancers11020164, PubMed 30717152

Publications 2017

Anumala UR, Waaler J, Nkizinkiko Y, Ignatev A, Lazarow K, Lindemann P, Olsen PA, Murthy S, Obaji E, Majouga AG, Leonov S, von Kries JP, Lehtiö L, Krauss S, Nazaré M (2017)
Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach
J Med Chem, 60 (24), 10013-10025
DOI 10.1021/acs.jmedchem.7b00883, PubMed 29155568

Lund K, Olsen CE, Wong JJW, Olsen PA, Solberg NT, Høgset A, Krauss S, Selbo PK (2017)
5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin
J Exp Clin Cancer Res, 36 (1), 187
DOI 10.1186/s13046-017-0662-6, PubMed 29258566

Solberg NT, Waaler J, Lund K, Mygland L, Olsen PA, Krauss S (2017)
TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer
Mol Cancer Res, 16 (3), 543-553
DOI 10.1158/1541-7786.MCR-17-0362, PubMed 29222171

Publications 2015

Olsen PA, Lund K, Krauss S (2015)
Expression profiling of wild type and β-catenin gene disrupted human BxPC-3 pancreatic adenocarcinoma cells
Genom Data, 4, 150-2
DOI 10.1016/j.gdata.2015.04.010, PubMed 26484203

Publications 2014

Olsen PA, Solberg NT, Lund K, Vehus T, Gelazauskaite M, Wilson SR, Krauss S (2014)
Implications of targeted genomic disruption of β-catenin in BxPC-3 pancreatic adenocarcinoma cells
PLoS One, 9 (12), e115496
DOI 10.1371/journal.pone.0115496, PubMed 25536063

Roberg-Larsen H, Lund K, Vehus T, Solberg N, Vesterdal C, Misaghian D, Olsen PA, Krauss S, Wilson SR, Lundanes E (2014)
Highly automated nano-LC/MS-based approach for thousand cell-scale quantification of side chain-hydroxylated oxysterols
J Lipid Res, 55 (7), 1531-6
DOI 10.1194/jlr.D048801, PubMed 24792927

Publications 2012

Roberg-Larsen H, Strand MF, Grimsmo A, Olsen PA, Dembinski JL, Rise F, Lundanes E, Greibrokk T, Krauss S, Wilson SR (2012)
High sensitivity measurements of active oxysterols with automated filtration/filter backflush-solid phase extraction-liquid chromatography-mass spectrometry
J Chromatogr A, 1255, 291-7
DOI 10.1016/j.chroma.2012.02.002, PubMed 22410154

Publications 2010

Olsen PA, Gelazauskaite M, Randøl M, Krauss S (2010)
Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction
BMC Mol Biol, 11, 35
DOI 10.1186/1471-2199-11-35, PubMed 20459736

Publications 2008

Olsen PA, Solhaug A, Booth JA, Gelazauskaite M, Krauss S (2008)
Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases
DNA Repair (Amst), 8 (3), 298-308
DOI 10.1016/j.dnarep.2008.11.011, PubMed 19071233

Publications 2006

Olsen PA (2006)
Targeted sequence alterations in the genomes of mammaliancells mediated by oligonucleotides
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 411, 1 b. (flere pag.)
BIBSYS 061011363, ISBN 82-8072-845-7

Publications 2005

Olsen PA, Randol M, Krauss S (2005)
Implications of cell cycle progression on functional sequence correction by short single-stranded DNA oligonucleotides
Gene Ther, 12 (6), 546-51
DOI 10.1038/sj.gt.3302454, PubMed 15674399

Olsen PA, Randøl M, Luna L, Brown T, Krauss S (2005)
Genomic sequence correction by single-stranded DNA oligonucleotides: role of DNA synthesis and chemical modifications of the oligonucleotide ends
J Gene Med, 7 (12), 1534-44
DOI 10.1002/jgm.804, PubMed 16025558

Publications 2003

Johannessen M, Olsen PA, Johansen B, Seternes OM, Moens U (2003)
Activation of the coactivator four-and-a-half-LIM-only protein FHL2 and the c-fos promoter through inhibition of protein phosphatase 2A
Biochem Pharmacol, 65 (8), 1317-28
DOI 10.1016/s0006-2952(03)00071-6, PubMed 12694872

Johannessen M, Olsen PA, Sørensen R, Johansen B, Seternes OM, Moens U (2003)
A role of the TATA box and the general co-activator hTAF(II)130/135 in promoter-specific trans-activation by simian virus 40 small t antigen
J Gen Virol, 84 (Pt 7), 1887-1897
DOI 10.1099/vir.0.19057-0, PubMed 12810884

Olsen PA, McKeen C, Krauss S (2003)
Branched oligonucleotides induce in vivo gene conversion of a mutated EGFP reporter
Gene Ther, 10 (21), 1830-40
DOI 10.1038/sj.gt.3302079, PubMed 12960973