Einar Hopp
- Consultant radiologist; MD, PhD
Einar Hopp, MD, PhD is the leader for the research group Non-invasive Cardiac Imaging.
Non-invasive cardiac imaging includes nuclear medicine techniques like SPECT and PET/CT, Computed tomography (CT) and magnetic resonance imaging (MRI). Measurement of metabolism, oxygen demand and perfusion is ever evolving in nuclear medicine, and novel pharmacological agents cause new possibilities and method refinement. Cardiac CT experiencex hardware advances increasing uptake speed and decreasing radiation.
Analytic advances include dynamic imaging with functional assessment, and more complex algorithms providing flow estimation. Trends in cardiac MRI include regional function with 4D motion and deformation analyses, and detailed tissue characterization through direct T1, T2 and T2* measurement.
Members of the group participate in different clinical projects, providing primary and secondary end points on ischemic heart disease, cardiomyopathies, valvular heart disease and severe heart failure.
Imaging studies focus on method development, validation and refinement.
Publications 2024
No adverse association between exercise exposure and diffuse myocardial fibrosis in male endurance athletes
Sci Rep, 14 (1), 6581
DOI 10.1038/s41598-024-57233-5, PubMed 38503845
Differentiation of Myocardial Properties in Physiological Athletic Cardiac Remodeling and Mild Hypertrophic Cardiomyopathy
Biomedicines, 12 (2)
DOI 10.3390/biomedicines12020420, PubMed 38398022
Left atrial volume as risk marker: is minimum volume superior to maximum volume?
Eur Heart J Cardiovasc Imaging, 25 (11), 1575-1576
DOI 10.1093/ehjci/jeae136, PubMed 38781443
Publications 2023
Mechanical Dyssynchrony Combined with Septal Scarring Reliably Identifies Responders to Cardiac Resynchronization Therapy
J Clin Med, 12 (18)
DOI 10.3390/jcm12186108, PubMed 37763048
Does the clot burden as assessed by the Mean Bilateral Proximal Extension of the Clot score reflect mortality and adverse outcome after pulmonary embolism?
Acta Radiol Open, 12 (6), 20584601231187094
DOI 10.1177/20584601231187094, PubMed 37426515
Cardiac Magnetic Resonance Identifies Responders to Cardiac Resynchronization Therapy with an Assessment of Septal Scar and Left Ventricular Dyssynchrony
J Clin Med, 12 (22)
DOI 10.3390/jcm12227182, PubMed 38002795
Cytokine pattern in patients with ST-elevation myocardial infarction treated with the interleukin-6 receptor antagonist tocilizumab
Open Heart, 10 (2)
DOI 10.1136/openhrt-2023-002301, PubMed 37591633
Ventricular arrhythmias in arrhythmic mitral valve syndrome-a prospective continuous long-term cardiac monitoring study
Europace, 25 (2), 506-516
DOI 10.1093/europace/euac182, PubMed 36256597
Publications 2022
Electrical markers and arrhythmic risk associated with myocardial fibrosis in mitral valve prolapse
Europace, 24 (7), 1156-1163
DOI 10.1093/europace/euac017, PubMed 35226070
Visual Presence of Mechanical Dyssynchrony Combined With Septal Scarring Identifies Responders to Cardiac Resynchronization Therapy
JACC Cardiovasc Imaging, 15 (12), 2151-2153
DOI 10.1016/j.jcmg.2022.06.020, PubMed 36481085
Effects of pulmonary rehabilitation on cardiac magnetic resonance parameters in patients with persistent dyspnea following pulmonary embolism
Int J Cardiol Heart Vasc, 40, 100995
DOI 10.1016/j.ijcha.2022.100995, PubMed 35345773
Cardiac Structure and Function in Epilepsy Patients with Drug-Resistant Convulsive Seizures
Case Rep Neurol, 14 (1), 88-97
DOI 10.1159/000522237, PubMed 35431877
Scar imaging in the dyssynchronous left ventricle: Accuracy of myocardial metabolism by positron emission tomography and function by echocardiographic strain
Int J Cardiol, 372, 122-129
DOI 10.1016/j.ijcard.2022.11.042, PubMed 36460211
Publications 2021
Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction
J Am Coll Cardiol, 77 (15), 1845-1855
DOI 10.1016/j.jacc.2021.02.049, PubMed 33858620
Left ventricular regional glucose metabolism in combination with septal scar extent identifies CRT responders
Eur J Nucl Med Mol Imaging, 48 (8), 2437-2446
DOI 10.1007/s00259-020-05161-7, PubMed 33416956
Association between myocardial fibrosis, as assessed with cardiac magnetic resonance T1 mapping, and persistent dyspnea after pulmonary embolism
Int J Cardiol Heart Vasc, 38, 100935
DOI 10.1016/j.ijcha.2021.100935, PubMed 35005213
Lateral Wall Dysfunction Signals Onset of Progressive Heart Failure in Left Bundle Branch Block
JACC Cardiovasc Imaging, 14 (11), 2059-2069
DOI 10.1016/j.jcmg.2021.04.017, PubMed 34147454
3.0T MR Coronary Angiography after Arterial Switch Operation for Transposition of The Great Arteries-Gd-FLASH Versus Non-Enhanced SSFP. A Feasibility Study
Congenit. Heart Dis., 16 (2), 107-121
DOI 10.32604/CHD.2021.014164
Tricuspid Annulus Disjunction: Novel Findings by Cardiac Magnetic Resonance in Patients With Mitral Annulus Disjunction
JACC Cardiovasc Imaging, 14 (8), 1535-1543
DOI 10.1016/j.jcmg.2021.01.028, PubMed 33744128
Publications 2020
Imaging of patients with COVID-19
Tidsskr. Nor. Laegeforen., 140 (8), 756-760
Acute redistribution of regional left ventricular work by cardiac resynchronization therapy determines long-term remodelling
Eur Heart J Cardiovasc Imaging, 21 (6), 619-628
DOI 10.1093/ehjci/jeaa003, PubMed 32031587
CT imaging of the Eustachian tube using focal contrast medium administration: a feasibility study in humans
Acta Radiol Open, 9 (1), 2058460119900435
DOI 10.1177/2058460119900435, PubMed 32030198
Regional myocardial work by cardiac magnetic resonance and non-invasive left ventricular pressure: a feasibility study in left bundle branch block
Eur Heart J Cardiovasc Imaging, 21 (2), 143-153
DOI 10.1093/ehjci/jez231, PubMed 31599327
Cardiac Phenotypes and Markers of Adverse Outcome in Elite Athletes With Ventricular Arrhythmias
JACC Cardiovasc Imaging, 14 (1), 148-158
DOI 10.1016/j.jcmg.2020.07.039, PubMed 33129723
Septal contraction predicts acute haemodynamic improvement and paced QRS width reduction in cardiac resynchronization therapy
Eur Heart J Cardiovasc Imaging, 21 (8), 845-852
DOI 10.1093/ehjci/jez315, PubMed 31925420
Imaging predictors of response to cardiac resynchronization therapy: left ventricular work asymmetry by echocardiography and septal viability by cardiac magnetic resonance
Eur Heart J, 41 (39), 3813-3823
DOI 10.1093/eurheartj/ehaa603, PubMed 32918449
Diagnostic imaging of COVID-19 patients
Tidsskr Nor Laegeforen, 140 (8)
DOI 10.4045/tidsskr.20.0332, PubMed 32463192
Publications 2019
Rationale for the ASSAIL-MI-trial: a randomised controlled trial designed to assess the effect of tocilizumab on myocardial salvage in patients with acute ST-elevation myocardial infarction (STEMI)
Open Heart, 6 (2), e001108
DOI 10.1136/openhrt-2019-001108, PubMed 31673391
An image fusion tool for echo-guided left ventricular lead placement in cardiac resynchronization therapy: Performance and workflow integration analysis
Echocardiography, 36 (10), 1834-1845
DOI 10.1111/echo.14483, PubMed 31628770
Increased levels of sST2 in patients with mitral annulus disjunction and ventricular arrhythmias
Open Heart, 6 (1), e001016
DOI 10.1136/openhrt-2019-001016, PubMed 31168386
Mechanism of Abnormal Septal Motion in Left Bundle Branch Block: Role of Left Ventricular Wall Interactions and Myocardial Scar
JACC Cardiovasc Imaging, 12 (12), 2402-2413
DOI 10.1016/j.jcmg.2018.11.030, PubMed 30772230
Publications 2018
[Will radiologists be replaced by artificial intelligence?]
Tidsskr Nor Laegeforen, 138 (17)
DOI 10.4045/tidsskr.18.0587, PubMed 30378411
Will radiologists be replaced by artificial intelligence?
Tidsskr. Nor. Laegeforen., 138 (17), 1610-1612
In vivo estimation of elastic heterogeneity in an infarcted human heart
Biomech Model Mechanobiol, 17 (5), 1317-1329
DOI 10.1007/s10237-018-1028-5, PubMed 29774440
The Mitral Annulus Disjunction Arrhythmic Syndrome
J Am Coll Cardiol, 72 (14), 1600-1609
DOI 10.1016/j.jacc.2018.07.070, PubMed 30261961
Abnormally wide eustachian tubes involving the sphenoid bone: A collection
Laryngoscope Investig Otolaryngol, 3 (3), 214-217
DOI 10.1002/lio2.158, PubMed 30062137
The cartilaginous Eustachian tube: Reliable CT measurement and impact of the length
Am J Otolaryngol, 39 (4), 436-440
DOI 10.1016/j.amjoto.2018.04.010, PubMed 29685379
[Not Available]
Tidsskr Nor Laegeforen, 138 (1)
DOI 10.4045/tidsskr.17.1078, PubMed 29313616
"It is important for the patient to carry with them the provided pacemaker card at any time"
Tidsskr. Nor. Laegeforen., 138 (1), 9-10
Cardiac resynchronization therapy when no lateral pacing option exists: vectorcardiographic guided non-lateral left ventricular lead placement predicts acute hemodynamic response
Europace, 20 (8), 1294-1302
DOI 10.1093/europace/eux249, PubMed 29036446
Contractility surrogates derived from three-dimensional lead motion analysis and prediction of acute haemodynamic response to CRT
Open Heart, 5 (2), e000874
DOI 10.1136/openhrt-2018-000874, PubMed 30613408
Diffuse myocardial fibrosis in adolescents operated with arterial switch for transposition of the great arteries - A CMR study
Int J Cardiol, 276, 100-106
DOI 10.1016/j.ijcard.2018.11.107, PubMed 30527348
Can visual analogue scale be used in radiologic subjective image quality assessment?
Pediatr Radiol, 48 (11), 1567-1575
DOI 10.1007/s00247-018-4187-8, PubMed 29974179
Publications 2017
[MRI examination of patients with pacemakers or implanted defibrillators]
Tidsskr Nor Laegeforen, 137 (21)
DOI 10.4045/tidsskr.17.0815, PubMed 29135169
MRI examination of patients with pacemaker or implanted cardiac arrest
Tidsskr. Nor. Laegeforen., 137 (21), 1668-1669
Comparison of Electrocardiography Markers and Speckle Tracking Echocardiography for Assessment of Left Ventricular Myocardial Scar Burden in Patients With Previous Myocardial Infarction
Am J Cardiol, 119 (9), 1307-1312
DOI 10.1016/j.amjcard.2017.01.020, PubMed 28274572
Publications 2016
Exercise capacity and peak oxygen consumption in asymptomatic patients with chronic aortic regurgitation
Int J Cardiol, 223, 688-692
DOI 10.1016/j.ijcard.2016.08.237, PubMed 27568990
CT imaging of the eustachian tube using focal contrast medium administration: a feasibility study
Laryngoscope Investig Otolaryngol, 1 (4), 83-87
DOI 10.1002/lio2.24, PubMed 28894806
Strain echocardiography is related to fibrosis and ventricular arrhythmias in hypertrophic cardiomyopathy
Eur Heart J Cardiovasc Imaging, 17 (6), 613-21
DOI 10.1093/ehjci/jew005, PubMed 26873460
CDH23 Related Hearing Loss: A New Genetic Risk Factor for Semicircular Canal Dehiscence?
Otol Neurotol, 37 (10), 1583-1588
DOI 10.1097/MAO.0000000000001210, PubMed 27631835
Insertion Depth in Cochlear Implantation and Outcome in Residual Hearing and Vestibular Function
Ear Hear, 37 (2), e129-37
DOI 10.1097/AUD.0000000000000241, PubMed 26524566
Two male sibs with severe micrognathia and a missense variant in MED12
Eur J Med Genet, 59 (8), 367-72
DOI 10.1016/j.ejmg.2016.06.001, PubMed 27286923
Comparison of patients with early-phase arrhythmogenic right ventricular cardiomyopathy and right ventricular outflow tract ventricular tachycardia
Eur Heart J Cardiovasc Imaging, 18 (1), 62-69
DOI 10.1093/ehjci/jew014, PubMed 26903598
Publications 2015
Results of comprehensive diagnostic work-up in 'idiopathic' dilated cardiomyopathy
Open Heart, 2 (1), e000271
DOI 10.1136/openhrt-2015-000271, PubMed 26468400
Contemporary Outcome in Patients With Idiopathic Dilated Cardiomyopathy
Am J Cardiol, 116 (6), 952-9
DOI 10.1016/j.amjcard.2015.06.022, PubMed 26233575
Controlled release metoprolol for aortic regurgitation: a randomised clinical trial
Heart, 102 (3), 191-7
DOI 10.1136/heartjnl-2015-308416, PubMed 26661319
Publications 2013
Long axis strain by MRI and echocardiography in a postmyocardial infarct population
J Magn Reson Imaging, 40 (5), 1247-51
DOI 10.1002/jmri.24485, PubMed 24214923
Perfusion MRI at rest in subacute and chronic myocardial infarct
Acta Radiol, 54 (4), 401-11
DOI 10.1177/0284185113475605, PubMed 23401603
Scalar position in cochlear implant surgery and outcome in residual hearing and the vestibular system
Int J Audiol, 53 (2), 121-7
DOI 10.3109/14992027.2013.854413, PubMed 24304359
Publications 2011
Regional myocardial function after intracoronary bone marrow cell injection in reperfused anterior wall infarction - a cardiovascular magnetic resonance tagging study
J Cardiovasc Magn Reson, 13 (1), 22
DOI 10.1186/1532-429X-13-22, PubMed 21414223
Publications 2009
Long-term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: the ASTAMI randomised, controlled study
Heart, 95 (24), 1983-9
DOI 10.1136/hrt.2009.178913, PubMed 19833610
Left ventricle longitudinal deformation assessment by mitral annulus displacement or global longitudinal strain in chronic ischemic heart disease: are they interchangeable?
J Am Soc Echocardiogr, 22 (7), 823-30
DOI 10.1016/j.echo.2009.04.023, PubMed 19505792
Publications 2008
Noninvasive separation of large, medium, and small myocardial infarcts in survivors of reperfused ST-elevation myocardial infarction: a comprehensive tissue Doppler and speckle-tracking echocardiography study
Circ Cardiovasc Imaging, 1 (3), 189-96, 2 p following 196
DOI 10.1161/CIRCIMAGING.108.784900, PubMed 19808542
Autonomic heart rate control at rest and during unloading of the right ventricle in repaired tetralogy of Fallot in adolescents
Am J Cardiol, 102 (8), 1085-9
DOI 10.1016/j.amjcard.2008.05.065, PubMed 18929714
Publications 2007
Global longitudinal strain measured by two-dimensional speckle tracking echocardiography is closely related to myocardial infarct size in chronic ischaemic heart disease
Clin Sci (Lond), 113 (6), 287-96
DOI 10.1042/CS20070066, PubMed 17501720
Publications 2006
Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction
N Engl J Med, 355 (12), 1199-209
DOI 10.1056/NEJMoa055706, PubMed 16990383
Central line-associated venous late effects in children without prior history of thrombosis
Acta Paediatr, 95 (9), 1060-5
DOI 10.1080/08035250500499457, PubMed 16938750
Publications 2005
Monitoring urinary bladder volume and detecting post-operative urinary retention in children with an ultrasound scanner
Acta Anaesthesiol Scand, 49 (10), 1456-9
DOI 10.1111/j.1399-6576.2005.00817.x, PubMed 16223389
Publications 2004
Mylohyoid herniation of the sublingual gland diagnosed by magnetic resonance imaging
Dentomaxillofac Radiol, 33 (5), 351-3
DOI 10.1259/dmfr/31454077, PubMed 15585816
Publications 1994
Rheumatoid arthritis: a complication of interferon therapy
J Okla State Med Assoc, 87 (5), 228-30
PubMed 8051581
Publications 1990
Ligament injuries associated with tibial plateau fractures
Clin Orthop Relat Res (250), 226-33
PubMed 2293934
Publications 1988
Postdecompression lumbar instability
Clin Orthop Relat Res, 227, 143-51
PubMed 2962798
Publications 1986
Molecular cloning of rotavirus genome
Medicina (B Aires), 46 (6), 693-7
PubMed 3041173