Tove Lekva

  • Scientist; PhD
 

Publications 2024

Andreou D, Steen NE, Mørch-Johnsen L, Jørgensen KN, Wortinger LA, Barth C, Szabo A, O'Connell KS, Lekva T, Hjell G, Johansen IT, Ormerod MBEG, Haukvik UK, Aukrust P, Djurovic S, Yolken RH, Andreassen OA, Ueland T, Agartz I (2024)
Toxoplasma gondii infection associated with inflammasome activation and neuronal injury
Sci Rep, 14 (1), 5327
DOI 10.1038/s41598-024-55887-9, PubMed 38438515

Damås JK, Otterdal K, Astrup E, Lekva T, Janardhanan J, Michelsen A, Aukrust P, Varghese GM, Ueland T (2024)
Canonical notch activation in patients with scrub typhus: association with organ dysfunction and poor outcome
Infection (in press)
DOI 10.1007/s15010-024-02192-2, PubMed 38502427

Falch CM, Godang K, Lekva T, Ueland T, Heck A, Bollerslev J, Olarescu NC (2024)
Long-term depot specific changes in adipose tissue after treatment of acromegaly
Eur J Endocrinol, 190 (3), K37-K42
DOI 10.1093/ejendo/lvae016, PubMed 38401530

Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2024)
Retraction Note: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 14 (1), 3704
DOI 10.1038/s41598-024-54117-6, PubMed 38355714

Ueland T, Butt N, Lekva T, Ørn S, Manhenke C, Aukrust P, Larsen AI (2024)
High dose statin treatment reduces circulating Dickkopf-1 following acute myocardial infarction
Int J Cardiol, 132035 (in press)
DOI 10.1016/j.ijcard.2024.132035, PubMed 38604450

Varden Gjerde K, Bartz-Johannessen C, Steen VM, Andreassen OA, Steen NE, Ueland T, Lekva T, Rettenbacher M, Joa I, Reitan SK, Johnsen E, Kroken RA (2024)
Cellular adhesion molecules in drug-naïve and previously medicated patients with schizophrenia-spectrum disorders
Schizophr Res, 267, 223-229 (in press)
DOI 10.1016/j.schres.2024.03.029, PubMed 38574562

Publications 2023

Heck A, Godang K, Lekva T, Markussen KN, De Vincentis S, Ueland T, Bollerslev J (2023)
Endocortical Trabecularization in Acromegaly: The Cause for the Paradoxically Increased Vertebral Fracture Risk?
JBMR Plus, 7 (10), e10787
DOI 10.1002/jbm4.10787, PubMed 37808394

Jensen SB, Sheikh MA, Akkouh IA, Szabo A, O'Connell KS, Lekva T, Engh JA, Agartz I, Elvsåshagen T, Ormerod MBEG, Weibell MA, Johnsen E, Kroken RA, Melle I, Drange OK, Nærland T, Vaaler AE, Westlye LT, Aukrust P, Djurovic S, Eiel Steen N, Andreassen OA, Ueland T (2023)
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
Schizophr Bull, 49 (3), 635-645
DOI 10.1093/schbul/sbac191, PubMed 36462169

Lekva T, Michelsen AE, Roland MCP, Norwitz ER, Estensen ME, Olstad OK, Akkouh IA, Henriksen T, Bollerslev J, Aukrust P, Ueland T (2023)
Increased ferroptosis in leukocytes from preeclamptic women involving the long non-coding taurine upregulated gene 1 (TUG1)
J Intern Med, 295 (2), 181-195
DOI 10.1111/joim.13732, PubMed 37870937

Lekva T, Sundaram AYF, Roland MCP, Åsheim J, Michelsen AE, Norwitz ER, Aukrust P, Gilfillan GD, Ueland T (2023)
Platelet and mitochondrial RNA is decreased in plasma-derived extracellular vesicles in women with preeclampsia-an exploratory study
BMC Med, 21 (1), 458
DOI 10.1186/s12916-023-03178-x, PubMed 37996819

Skytte HN, Christensen JJ, Gunnes N, Holven KB, Lekva T, Henriksen T, Michelsen TM, Roland MCP (2023)
Metabolic profiling of pregnancies complicated by preeclampsia: A longitudinal study
Acta Obstet Gynecol Scand, 102 (3), 334-343
DOI 10.1111/aogs.14505, PubMed 36647289

Skytte HN, Roland MCP, Christensen JJ, Holven KB, Lekva T, Gunnes N, Michelsen TM (2023)
Maternal metabolic profiling across body mass index groups: An exploratory longitudinal study
Acta Obstet Gynecol Scand, 103 (3), 540-550
DOI 10.1111/aogs.14750, PubMed 38083835

Publications 2022

Engh JA, Ueland T, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Hope S, Høegh MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Wedervang-Resell K, Weibell MA, Westlye LT, Djurovic S et al. (2022)
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Schizophr Bull, 48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169

Fosheim IK, Jacobsen DP, Sugulle M, Alnaes-Katjavivi P, Fjeldstad HES, Ueland T, Lekva T, Staff AC (2022)
Serum amyloid A1 and pregnancy zone protein in pregnancy complications and correlation with markers of placental dysfunction
Am J Obstet Gynecol MFM, 5 (1), 100794
DOI 10.1016/j.ajogmf.2022.100794, PubMed 36334725

Kristiansen O, Roland MC, Zucknick M, Reine TM, Kolset SO, Henriksen T, Lekva T, Michelsen T (2022)
Maternal body mass index and placental weight: a role for fetal insulin, maternal insulin and leptin
J Endocrinol Invest, 45 (11), 2105-2121
DOI 10.1007/s40618-022-01842-2, PubMed 35781790

Lekva T, Ueland T, Halvorsen B, Murphy SL, Dyrhol-Riise AM, Tveita A, Finbråten AK, Mathiessen A, Müller KE, Aaløkken TM, Skjønsberg OH, Lerum TV, Aukrust P, Dahl TB (2022)
Markers of cellular senescence is associated with persistent pulmonary pathology after COVID-19 infection
Infect Dis (Lond), 54 (12), 918-923
DOI 10.1080/23744235.2022.2113135, PubMed 35984738

Pervjakova N, Moen GH, Borges MC, Ferreira T, Cook JP, Allard C, Beaumont RN, Canouil M, Hatem G, Heiskala A, Joensuu A, Karhunen V, Kwak SH, Lin FTJ, Liu J, Rifas-Shiman S, Tam CH, Tam WH, Thorleifsson G, Andrew T, Auvinen J, Bhowmik B, Bonnefond A, Delahaye F, Demirkan A et al. (2022)
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes
Hum Mol Genet, 31 (19), 3377-3391
DOI 10.1093/hmg/ddac050, PubMed 35220425

Sheikh MA, O'Connell KS, Lekva T, Szabo A, Akkouh IA, Osete JR, Agartz I, Engh JA, Andreou D, Boye B, Bøen E, Elvsåshagen T, Hope S, Frogner Werner MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Melle I, Drange OK, Morken G, Nærland T, Sørensen K, Vaaler AE, Weibell MA et al. (2022)
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Biol Psychiatry, 93 (2), 187-196
DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530

Vestad B, Ueland T, Lerum TV, Dahl TB, Holm K, Barratt-Due A, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Tonby K, Hoel H, Olsen IC, Henriksen KN, Tveita A, Manotheepan R, Haugli M, Eiken R, Berg Å, Halvorsen B, Lekva T, Ranheim T, Michelsen AE, Kildal AB, Johannessen A, Thoresen L et al. (2022)
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
J Intern Med, 291 (6), 801-812
DOI 10.1111/joim.13458, PubMed 35212063

Publications 2021

Lekva T, Jacobsen DP, Sugulle M, Moe K, Fjeldstad HES, Dechend R, Staff AC (2021)
Circulating HLA-G and its association with cardiovascular markers in pregnancy
J Reprod Immunol, 146, 103331
DOI 10.1016/j.jri.2021.103331, PubMed 34030048

Lekva T, Roland MCP, Estensen ME, Norwitz ER, Tilburgs T, Henriksen T, Bollerslev J, Normann KR, Magnus P, Olstad OK, Aukrust P, Ueland T (2021)
Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence
Sci Rep, 11 (1), 19735
DOI 10.1038/s41598-021-99140-z, PubMed 34611223

Lekva T, Roland MCP, Estensen ME, Norwitz ER, Tilburgs T, Henriksen T, Bollerslev J, Normann KR, Magnus P, Olstad OK, Aukrust P, Ueland T (2021)
Author Correction: Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence
Sci Rep, 11 (1), 22572
DOI 10.1038/s41598-021-00917-z, PubMed 34782619

Rai AS, Sletner L, Jenum AK, Øverby NC, Stafne SN, Lekva T, Pripp AH, Sagedal LR (2021)
Identifying women with gestational diabetes based on maternal characteristics: an analysis of four Norwegian prospective studies
BMC Pregnancy Childbirth, 21 (1), 615
DOI 10.1186/s12884-021-04086-9, PubMed 34496778

Roland MCP, Godang K, Aukrust P, Henriksen T, Lekva T (2021)
Low CETP activity and unique composition of large VLDL and small HDL in women giving birth to small-for-gestational age infants
Sci Rep, 11 (1), 6213
DOI 10.1038/s41598-021-85777-3, PubMed 33737686

Szabo A, O'Connell KS, Ueland T, Sheikh MA, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Engh JA, Hope S, Collier Høegh M, Joa I, Johnsen E, Kroken RA, Vik Lagerberg T, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Sørensen K et al. (2021)
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
Brain Behav Immun, 99, 299-306
DOI 10.1016/j.bbi.2021.10.017, PubMed 34758379

Ueland T, Astrup E, Otterdal K, Lekva T, Janardhanan J, Prakash JAJ, Thomas K, Michelsen AE, Aukrust P, Varghese GM, Damås JK (2021)
Secreted Wnt antagonists in scrub typhus
PLoS Negl Trop Dis, 15 (4), e0009185
DOI 10.1371/journal.pntd.0009185, PubMed 33914733

Publications 2020

Arain F, Abraityte A, Bogdanova M, Solberg OG, Michelsen AE, Lekva T, Aakhus S, Holm S, Halvorsen B, Finsen AV, Vinge LE, Nymo S, Espeland T, Ranheim T, Aukrust P, Vaage IJ, Auensen A, Gullestad L, Ueland T (2020)
YKL-40 (Chitinase-3-Like Protein 1) Serum Levels in Aortic Stenosis
Circ Heart Fail, 13 (10), e006643
DOI 10.1161/CIRCHEARTFAILURE.119.006643, PubMed 32962417

Eieland AK, Normann KR, Sundaram AYM, Nyman TA, Øystese KAB, Lekva T, Berg JP, Bollerslev J, Olarescu NC (2020)
Distinct Pattern of Endoplasmic Reticulum Protein Processing and Extracellular Matrix Proteins in Functioning and Silent Corticotroph Pituitary Adenomas
Cancers (Basel), 12 (10)
DOI 10.3390/cancers12102980, PubMed 33066652

Jacobsen DP, Lekva T, Moe K, Fjeldstad HES, Johnsen GM, Sugulle M, Staff AC (2020)
Pregnancy and postpartum levels of circulating maternal sHLA-G in preeclampsia
J Reprod Immunol, 143, 103249
DOI 10.1016/j.jri.2020.103249, PubMed 33254097

Lekva T, Gullestad L, Broch K, Aukrust P, Andreassen AK, Ueland T (2020)
Distinct patterns of soluble leukocyte activation markers are associated with etiology and outcomes in precapillary pulmonary hypertension
Sci Rep, 10 (1), 18540
DOI 10.1038/s41598-020-75654-w, PubMed 33122779

Lekva T, Sugulle M, Moe K, Redman C, Dechend R, Staff AC (2020)
Multiplex Analysis of Circulating Maternal Cardiovascular Biomarkers Comparing Preeclampsia Subtypes
Hypertension, 75 (6), 1513-1522
DOI 10.1161/HYPERTENSIONAHA.119.14580, PubMed 32336238

Roland MCP, Lekva T, Godang K, Bollerslev J, Henriksen T (2020)
Changes in maternal blood glucose and lipid concentrations during pregnancy differ by maternal body mass index and are related to birthweight: A prospective, longitudinal study of healthy pregnancies
PLoS One, 15 (6), e0232749
DOI 10.1371/journal.pone.0232749, PubMed 32574162

Ueland T, Estensen ME, Grindheim G, Bollerslev J, Henriksen T, Aukrust P, Aakhus S, Gullestad L, Lekva T (2020)
Elevated levels of the secreted wingless agonist R-spondin 3 in preeclamptic pregnancies
J Hypertens, 38 (7), 1347-1354
DOI 10.1097/HJH.0000000000002362, PubMed 31990902

Ueland T, Roland MCP, Michelsen AE, Godang K, Aukrust P, Henriksen T, Bollerslev J, Lekva T (2020)
Elevated Cholesteryl Ester Transfer Protein Activity Early in Pregnancy Predicts Prediabetes 5 Years Later
J Clin Endocrinol Metab, 105 (3)
DOI 10.1210/clinem/dgz119, PubMed 31665383

Wedervang-Resell K, Ueland T, Aukrust P, Friis S, Holven KB, H Johannessen C, Lekva T, Lonning V, Smelror RE, Szabo A, Andreassen OA, Myhre AM, Agartz I (2020)
Reduced levels of circulating adhesion molecules in adolescents with early-onset psychosis
NPJ Schizophr, 6 (1), 20
DOI 10.1038/s41537-020-00112-5, PubMed 32811840

Publications 2019

Godang K, Lekva T, Normann KR, Olarescu NC, Øystese KAB, Kolnes A, Ueland T, Bollerslev J, Heck A (2019)
Hip Structure Analyses in Acromegaly: Decrease of Cortical Bone Thickness After Treatment: A Longitudinal Cohort Study
JBMR Plus, 3 (12), e10240
DOI 10.1002/jbm4.10240, PubMed 31844828

Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2019)
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167 (Retracted)
DOI 10.1038/s41598-018-35367-7, PubMed 30655568

Ueland T, Michelsen AE, Aukrust P, Henriksen T, Bollerslev J, Lekva T (2019)
Adipokines and macrophage markers during pregnancy-Possible role for sCD163 in prediction and progression of gestational diabetes mellitus
Diabetes Metab Res Rev, 35 (3), e3114
DOI 10.1002/dmrr.3114, PubMed 30548982

Wedervang-Resell K, Friis S, Lonning V, Smelror RE, Johannessen C, Reponen EJ, Lyngstad SH, Lekva T, Aukrust P, Ueland T, Andreassen OA, Agartz I, Myhre AM (2019)
Increased interleukin 18 activity in adolescents with early-onset psychosis is associated with cortisol and depressive symptoms
Psychoneuroendocrinology, 112, 104513
DOI 10.1016/j.psyneuen.2019.104513, PubMed 31761332

Publications 2018

Lekva T, Godang K, Michelsen AE, Qvigstad E, Normann KR, Norwitz ER, Aukrust P, Henriksen T, Bollerslev J, Roland MCP, Ueland T (2018)
Prediction of Gestational Diabetes Mellitus and Pre-diabetes 5 Years Postpartum using 75 g Oral Glucose Tolerance Test at 14-16 Weeks' Gestation
Sci Rep, 8 (1), 13392
DOI 10.1038/s41598-018-31614-z, PubMed 30190548

Moen GH, LeBlanc M, Sommer C, Prasad RB, Lekva T, Normann KR, Qvigstad E, Groop L, Birkeland KI, Evans DM, Frøslie KF (2018)
Genetic determinants of glucose levels in pregnancy: genetic risk scores analysis and GWAS in the Norwegian STORK cohort
Eur J Endocrinol, 179 (6), 363-372
DOI 10.1530/EJE-18-0478, PubMed 30324795

Norum HM, Michelsen AE, Lekva T, Arora S, Otterdal K, Olsen MB, Kong XY, Gude E, Andreassen AK, Solbu D, Karason K, Dellgren G, Gullestad L, Aukrust P, Ueland T (2018)
Circulating delta-like Notch ligand 1 is correlated with cardiac allograft vasculopathy and suppressed in heart transplant recipients on everolimus-based immunosuppression
Am J Transplant, 19 (4), 1050-1060
DOI 10.1111/ajt.15141, PubMed 30312541

Publications 2017

Abraityte A, Vinge LE, Askevold ET, Lekva T, Michelsen AE, Ranheim T, Alfsnes K, Fiane A, Aakhus S, Lunde IG, Dahl CP, Aukrust P, Christensen G, Gullestad L, Yndestad A, Ueland T (2017)
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
J Mol Med (Berl), 95 (7), 767-777
DOI 10.1007/s00109-017-1529-1, PubMed 28357477

Falch CM, Sundaram AYM, Øystese KA, Normann KR, Lekva T, Silamikelis I, Eieland AK, Andersen M, Bollerslev J, Olarescu NC (2017)
Gene expression profiling of fast- and slow-growing non-functioning gonadotroph pituitary adenomas
Eur J Endocrinol, 178 (3), 295-307
DOI 10.1530/EJE-17-0702, PubMed 29259037

Hoseth EZ, Ueland T, Dieset I, Birnbaum R, Shin JH, Kleinman JE, Hyde TM, Mørch RH, Hope S, Lekva T, Abraityte AJ, Michelsen AE, Melle I, Westlye LT, Ueland T, Djurovic S, Aukrust P, Weinberger DR, Andreassen OA (2017)
A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue
Schizophr Bull, 43 (4), 881-890
DOI 10.1093/schbul/sbw183, PubMed 28049760

Lekva T, Michelsen AE, Aukrust P, Henriksen T, Bollerslev J, Ueland T (2017)
Leptin and adiponectin as predictors of cardiovascular risk after gestational diabetes mellitus
Cardiovasc Diabetol, 16 (1), 5
DOI 10.1186/s12933-016-0492-4, PubMed 28068986

Lekva T, Michelsen AE, Aukrust P, Paasche Roland MC, Henriksen T, Bollerslev J, Ueland T (2017)
CXC chemokine ligand 16 is increased in gestational diabetes mellitus and preeclampsia and associated with lipoproteins in gestational diabetes mellitus at 5 years follow-up
Diab Vasc Dis Res, 14 (6), 525-533
DOI 10.1177/1479164117728011, PubMed 28856928

Lekva T, Roland MCP, Michelsen AE, Friis CM, Aukrust P, Bollerslev J, Henriksen T, Ueland T (2017)
Large Reduction in Adiponectin During Pregnancy Is Associated With Large-for-Gestational-Age Newborns
J Clin Endocrinol Metab, 102 (7), 2552-2559
DOI 10.1210/jc.2017-00289, PubMed 28460045

Norum HM, Broch K, Michelsen AE, Lunde IG, Lekva T, Abraityte A, Dahl CP, Fiane AE, Andreassen AK, Christensen G, Aakhus S, Aukrust P, Gullestad L, Ueland T (2017)
The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy
J Cardiovasc Transl Res, 10 (4), 401-410
DOI 10.1007/s12265-017-9748-y, PubMed 28474304

Publications 2016

Lekva T, Lyle R, Roland MC, Friis C, Bianchi DW, Jaffe IZ, Norwitz ER, Bollerslev J, Henriksen T, Ueland T (2016)
Gene expression in term placentas is regulated more by spinal or epidural anesthesia than by late-onset preeclampsia or gestational diabetes mellitus
Sci Rep, 6, 29715
DOI 10.1038/srep29715, PubMed 27405415

Lekva T, Michelsen AE, Bollerslev J, Norwitz ER, Aukrust P, Henriksen T, Ueland T (2016)
Low circulating pentraxin 3 levels in pregnancy is associated with gestational diabetes and increased apoB/apoA ratio: a 5-year follow-up study
Cardiovasc Diabetol, 15, 23
DOI 10.1186/s12933-016-0345-1, PubMed 26842615

Lekva T, Norwitz ER, Aukrust P, Ueland T (2016)
Impact of Systemic Inflammation on the Progression of Gestational Diabetes Mellitus
Curr Diab Rep, 16 (4), 26
DOI 10.1007/s11892-016-0715-9, PubMed 26879309

Normann KR, Øystese KAB, Berg JP, Lekva T, Berg-Johnsen J, Bollerslev J, Olarescu NC (2016)
Selection and validation of reliable reference genes for RT-qPCR analysis in a large cohort of pituitary adenomas
Mol Cell Endocrinol, 437, 183-189
DOI 10.1016/j.mce.2016.08.030, PubMed 27561203

Publications 2015

Lekva T, Berg JP, Lyle R, Heck A, Bollerslev J, Ueland T (2015)
Alternative splicing of placental lactogen (CSH2) in somatotroph pituitary adenomas
Neuro Endocrinol Lett, 36 (2), 136-42
PubMed 26071582

Lekva T, Bollerslev J, Godang K, Roland MC, Friis CM, Voldner N, Henriksen T, Ueland T (2015)
β-cell dysfunction in women with previous gestational diabetes is associated with visceral adipose tissue distribution
Eur J Endocrinol, 173 (1), 63-70
DOI 10.1530/EJE-15-0153, PubMed 25877991

Lekva T, Bollerslev J, Norwitz ER, Aukrust P, Henriksen T, Ueland T (2015)
Aortic Stiffness and Cardiovascular Risk in Women with Previous Gestational Diabetes Mellitus
PLoS One, 10 (8), e0136892
DOI 10.1371/journal.pone.0136892, PubMed 26309121

Publications 2014

Astrup E, Janardhanan J, Otterdal K, Ueland T, Prakash JA, Lekva T, Strand ØA, Abraham OC, Thomas K, Damås JK, Mathews P, Mathai D, Aukrust P, Varghese GM (2014)
Cytokine network in scrub typhus: high levels of interleukin-8 are associated with disease severity and mortality
PLoS Negl Trop Dis, 8 (2), e2648
DOI 10.1371/journal.pntd.0002648, PubMed 24516677

Otterdal K, Janardhanan J, Astrup E, Ueland T, Prakash JA, Lekva T, Abraham OC, Thomas K, Damås JK, Mathews P, Mathai D, Aukrust P, Varghese GM (2014)
Increased endothelial and macrophage markers are associated with disease severity and mortality in scrub typhus
J Infect, 69 (5), 462-9
DOI 10.1016/j.jinf.2014.06.018, PubMed 24995849

Ueland T, Olarescu NC, Jørgensen AP, Otterdal K, Aukrust P, Godang K, Lekva T, Bollerslev J (2014)
Increased serum and bone matrix levels of the secreted Wnt antagonist DKK-1 in patients with growth hormone deficiency in response to growth hormone treatment
J Clin Endocrinol Metab, 100 (2), 736-43
DOI 10.1210/jc.2014-2912, PubMed 25459913

Publications 2013

Casar-Borota O, Heck A, Schulz S, Nesland JM, Ramm-Pettersen J, Lekva T, Alafuzoff I, Bollerslev J (2013)
Expression of SSTR2a, but not of SSTRs 1, 3, or 5 in somatotroph adenomas assessed by monoclonal antibodies was reduced by octreotide and correlated with the acute and long-term effects of octreotide
J Clin Endocrinol Metab, 98 (11), E1730-9
DOI 10.1210/jc.2013-2145, PubMed 24092823

Evang JA, Bollerslev J, Casar-Borota O, Lekva T, Ramm-Pettersen J, Berg JP (2013)
Different levels of various glucocorticoid-regulated genes in corticotroph adenomas
Endocrine, 44 (1), 220-7
DOI 10.1007/s12020-012-9871-0, PubMed 23315031

Godang K, Frøslie KF, Henriksen T, Isaksen GA, Voldner N, Lekva T, Ueland T, Bollerslev J (2013)
Umbilical cord levels of sclerostin, placental weight, and birth weight are predictors of total bone mineral content in neonates
Eur J Endocrinol, 168 (3), 371-8
DOI 10.1530/EJE-12-0531, PubMed 23221033

Lekva T, Berg JP, Heck A, Lyngvi Fougner S, Olstad OK, Ringstad G, Bollerslev J, Ueland T (2013)
Attenuated RORC expression in the presence of EMT progression in somatotroph adenomas following treatment with somatostatin analogs is associated with poor clinical recovery
PLoS One, 8 (6), e66927
DOI 10.1371/journal.pone.0066927, PubMed 23825587

Lekva T, Berg JP, Lyle R, Heck A, Ringstad G, Olstad OK, Michelsen AE, Casar-Borota O, Bollerslev J, Ueland T (2013)
Epithelial splicing regulator protein 1 and alternative splicing in somatotroph adenomas
Endocrinology, 154 (9), 3331-43
DOI 10.1210/en.2013-1051, PubMed 23825128

Lekva T, Bollerslev J, Sahraoui A, Scholz H, Bøyum H, Evang JA, Godang K, Aukrust P, Ueland T (2013)
Thioredoxin interacting protein is a potential regulator of glucose and energy homeostasis in endogenous Cushing's syndrome
PLoS One, 8 (5), e64247
DOI 10.1371/journal.pone.0064247, PubMed 23691179

Nytrøen K, Rustad LA, Erikstad I, Aukrust P, Ueland T, Lekva T, Gude E, Wilhelmsen N, Hervold A, Aakhus S, Gullestad L, Arora S (2013)
Effect of high-intensity interval training on progression of cardiac allograft vasculopathy
J Heart Lung Transplant, 32 (11), 1073-80
DOI 10.1016/j.healun.2013.06.023, PubMed 23906899

Publications 2012

Astrup E, Lekva T, Davì G, Otterdal K, Santilli F, Oie E, Halvorsen B, Damås JK, Raoult D, Vitale G, Olano JP, Ueland T, Aukrust P (2012)
A complex interaction between Rickettsia conorii and Dickkopf-1--potential role in immune evasion mechanisms in endothelial cells
PLoS One, 7 (9), e43638
DOI 10.1371/journal.pone.0043638, PubMed 23028464

Lekva T, Berg JP, Fougner SL, Olstad OK, Ueland T, Bollerslev J (2012)
Gene expression profiling identifies ESRP1 as a potential regulator of epithelial mesenchymal transition in somatotroph adenomas from a large cohort of patients with acromegaly
J Clin Endocrinol Metab, 97 (8), E1506-14
DOI 10.1210/jc.2012-1760, PubMed 22585092

Lekva T, Ueland T, Bøyum H, Evang JA, Godang K, Bollerslev J (2012)
TXNIP is highly regulated in bone biopsies from patients with endogenous Cushing's syndrome and related to bone turnover
Eur J Endocrinol, 166 (6), 1039-48
DOI 10.1530/EJE-11-1082, PubMed 22450549

Nytrøen K, Rustad LA, Aukrust P, Ueland T, Hallén J, Holm I, Rolid K, Lekva T, Fiane AE, Amlie JP, Aakhus S, Gullestad L (2012)
High-intensity interval training improves peak oxygen uptake and muscular exercise capacity in heart transplant recipients
Am J Transplant, 12 (11), 3134-42
DOI 10.1111/j.1600-6143.2012.04221.x, PubMed 22900793

Olarescu NC, Ueland T, Lekva T, Dahl TB, Halvorsen B, Aukrust P, Bollerslev J (2012)
Adipocytes as a source of increased circulating levels of nicotinamide phosphoribosyltransferase/visfatin in active acromegaly
J Clin Endocrinol Metab, 97 (4), 1355-62
DOI 10.1210/jc.2011-2417, PubMed 22319029

Publications 2011

Andersen GØ, Ueland T, Knudsen EC, Scholz H, Yndestad A, Sahraoui A, Smith C, Lekva T, Otterdal K, Halvorsen B, Seljeflot I, Aukrust P (2011)
Activin A levels are associated with abnormal glucose regulation in patients with myocardial infarction: potential counteracting effects of activin A on inflammation
Diabetes, 60 (5), 1544-51
DOI 10.2337/db10-1493, PubMed 21464440

Evang JA, Berg JP, Casar-Borota O, Lekva T, Kringen MK, Ramm-Pettersen J, Bollerslev J (2011)
Reduced levels of E-cadherin correlate with progression of corticotroph pituitary tumours
Clin Endocrinol (Oxf), 75 (6), 811-8
DOI 10.1111/j.1365-2265.2011.04109.x, PubMed 21595730

Ueland T, Lekva T, Otterdal K, Dahl TB, Olarescu NC, Jørgensen AP, Fougner KJ, Brixen K, Aukrust P, Bollerslev J (2011)
Increased serum and bone matrix levels of transforming growth factor {beta}1 in patients with GH deficiency in response to GH treatment
Eur J Endocrinol, 165 (3), 393-400
DOI 10.1530/EJE-11-0442, PubMed 21653735

Publications 2010

Fougner SL, Lekva T, Borota OC, Hald JK, Bollerslev J, Berg JP (2010)
The expression of E-cadherin in somatotroph pituitary adenomas is related to tumor size, invasiveness, and somatostatin analog response
J Clin Endocrinol Metab, 95 (5), 2334-42
DOI 10.1210/jc.2009-2197, PubMed 20335450

Publications 2009

Lekva T, Bollerslev J, Kristo C, Olstad OK, Ueland T, Jemtland R (2009)
The glucocorticoid-induced leucine zipper gene (GILZ) expression decreases after successful treatment of patients with endogenous Cushing's syndrome and may play a role in glucocorticoid-induced osteoporosis
J Clin Endocrinol Metab, 95 (1), 246-55
DOI 10.1210/jc.2009-0595, PubMed 19875485

Lekva T, Bollerslev J, Kristo CL, Olstad OK, Ueland T, Jemtland R (2009)
The Glucocorticoid-Induced Leucine Zipper Gene (GILZ) Expression Decreases after Successful Treatment of Patients with Endogenous Cushing's Syndrome and May Play a Role in Glucocorticoid-Induced Osteoporosis
Endocr Rev, 30 (7), 932
DOI 10.1210/edrv.30.7.9985, PubMed 28199557

Ueland T, Fougner SL, Godang K, Lekva T, Schurgers LJ, Scholz H, Halvorsen B, Schreiner T, Aukrust P, Bollerslev J (2009)
Associations between body composition, circulating interleukin-1 receptor antagonist, osteocalcin, and insulin metabolism in active acromegaly
J Clin Endocrinol Metab, 95 (1), 361-8
DOI 10.1210/jc.2009-0422, PubMed 19880791

Ueland T, Fougner SL, Godang K, Lekva T, Schurgers LJ, Scholz H, Halvorsen B, Schreiner T, Aukrust PL, Bollerslev J (2009)
Associations between Body Composition, Circulating Interleukin-1 Receptor Antagonist, Osteocalcin, and Insulin Metabolism in Active Acromegaly
Endocr Rev, 30 (7), 927
DOI 10.1210/edrv.30.7.9997, PubMed 28199500

Ueland T, Otterdal K, Lekva T, Halvorsen B, Gabrielsen A, Sandberg WJ, Paulsson-Berne G, Pedersen TM, Folkersen L, Gullestad L, Oie E, Hansson GK, Aukrust P (2009)
Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis
Arterioscler Thromb Vasc Biol, 29 (8), 1228-34
DOI 10.1161/ATVBAHA.109.189761, PubMed 19498175

Publications 2008

Pedersen ME, Fortunati D, Nielsen M, Brorson SH, Lekva T, Nissen-Meyer LS, Gautvik VT, Shahdadfar A, Gautvik KM, Jemtland R (2008)
Calmodulin-dependent kinase 1beta is expressed in the epiphyseal growth plate and regulates proliferation of mouse calvarial osteoblasts in vitro
Bone, 43 (4), 700-7
DOI 10.1016/j.bone.2008.06.006, PubMed 18620088

Publications 2007

Nissen-Meyer LS, Svalheim S, Taubøll E, Reppe S, Lekva T, Solberg LB, Melhus G, Reinholt FP, Gjerstad L, Jemtland R (2007)
Levetiracetam, phenytoin, and valproate act differently on rat bone mass, structure, and metabolism
Epilepsia, 48 (10), 1850-60
DOI 10.1111/j.1528-1167.2007.01176.x, PubMed 17634065

Page visits: 8338