Geir Hetland

  • Group leader; MD, PhD
  • +47 22 11 88 78
 

Publications 2024

Danilova E, Ezligini F, Stöckel C, Asakawa M, Hetland G (2024)
An evaluation of diethylhexyl phthalate free top & bottom in-line blood collection set with a new soft housing filter
Transfus Med (in press)
DOI 10.1111/tme.13091, PubMed 39243178

Hetland G, Fagerhol MK, Mirlashari MR, Nissen-Meyer LSH, Croci S, Lonati PA, Bonacini M, Salvarani C, Marvisi C, Bodio C, Muratore F, Borghi MO, Meroni PL (2024)
Elevated NET, Calprotectin, and Neopterin Levels Discriminate between Disease Activity in COVID-19, as Evidenced by Need for Hospitalization among Patients in Northern Italy
Biomedicines, 12 (4)
DOI 10.3390/biomedicines12040766, PubMed 38672123

Publications 2023

Fagerhol MK, Schultz NH, Mirlashari MR, Wiedmann MKH, Nissen-Meyer LSH, Søraas AVL, Hetland G (2023)
DNase analysed by a novel competitive assay in patients with complications after ChAdOx1 nCoV-19 vaccination and in normal unvaccinated blood donors
Scand J Immunol, 98 (1), e13274
DOI 10.1111/sji.13274, PubMed 37676118

Mahmood F, Nissen-Meyer LSH, Hetland G, Nentwich I (2023)
Assessing IgE sensitization profiles to birch and timothy grass pollen allergens in birch pollen allergic blood donors using an oligoplex specific IgE assay
Scand J Clin Lab Invest, 83 (7), 444-447
DOI 10.1080/00365513.2023.2255972, PubMed 37737679

Mirlashari MR, Vetlesen A, Nissen-Meyer LSH, Hetland G (2023)
Effects of storage on quality and function of acid-treated platelets with reduced HLA Class I surface expression
Transfus Med, 33 (4), 329-336
DOI 10.1111/tme.12983, PubMed 37356816

Reikvam H, Hetland G, Ezligini F, Dorsch K, Omert L, Dunham A, Almeland SK (2023)
Safety of hypoxic red blood cell administration in patients with transfusion-dependent hematological malignancies: An interim analysis
Transfus Apher Sci, 62 (5), 103755
DOI 10.1016/j.transci.2023.103755, PubMed 37423867

Publications 2022

Hetland G, Fagerhol MK, Dimova-Svetoslavova VP, Mirlashari MR, Nguyen NT, Lind A, Kolset SO, Søraas AVL, Nissen-Meyer LSH (2022)
Inflammatory markers calprotectin, NETs, syndecan-1 and neopterin in COVID-19 convalescent blood donors
Scand J Clin Lab Invest, 82 (6), 481-485
DOI 10.1080/00365513.2022.2123387, PubMed 36151851

Hetland G, Fagerhol MK, Wiedmann MKH, Søraas AVL, Mirlashari MR, Nissen-Meyer LSH, Istre MS, Holme PA, Schultz NH (2022)
Elevated NETs and Calprotectin Levels after ChAdOx1 nCoV-19 Vaccination Correlate with the Severity of Side Effects
Vaccines (Basel), 10 (8)
DOI 10.3390/vaccines10081267, PubMed 36016155

Meroni PL, Croci S, Lonati PA, Pregnolato F, Spaggiari L, Besutti G, Bonacini M, Ferrigno I, Rossi A, Hetland G, Hollan I, Cugno M, Tedesco F, Borghi MO, Salvarani C (2022)
Complement activation predicts negative outcomes in COVID-19: The experience from Northen Italian patients
Autoimmun Rev, 22 (1), 103232
DOI 10.1016/j.autrev.2022.103232, PubMed 36414219

Nissen-Meyer LSH, Ezligini F, Bergerud UE, Holtan A, Akkök ÇA, Danilova E, Hetland G (2022)
[Blood and emergency preparedness]
Tidsskr Nor Laegeforen, 142 (11)
DOI 10.4045/tidsskr.22.0494, PubMed 35997179

Publications 2021

Mirlashari MR, Vetlesen A, Nissen-Meyer LSH, Naper C, Tjønnfjord GE, Njerve IU, Ezligini F, Landmark BF, Meinke S, Sandgren P, Höglund P, Hetland G (2021)
HLA class I depletion by citric acid, and irradiation of apheresis platelets for transfusion of refractory patients
Transfusion, 61 (4), 1222-1234
DOI 10.1111/trf.16282, PubMed 33580979

Mirlashari MR, Vetlesen A, Nissen-Meyer LSH, Stensland ME, Singh SK, Nyman TA, Hetland G (2021)
Proteomic study of apheresis platelets made HLA class I deficient for transfusion of refractory patients
Proteomics Clin Appl, 15 (6), e2100022
DOI 10.1002/prca.202100022, PubMed 34510746

Publications 2020

Fagerhol MK, Johnson E, Tangen JM, Hollan I, Mirlashari MR, Nissen-Meyer LSH, Hetland G (2020)
NETs analysed by novel calprotectin-based assays in blood donors and patients with multiple myeloma or rheumatoid arthritis: A pilot study
Scand J Immunol, 91 (5), e12870
DOI 10.1111/sji.12870, PubMed 32034957

Hetland G, Johnson E, Bernardshaw SV, Grinde B (2020)
Can medicinal mushrooms have prophylactic or therapeutic effect against COVID-19 and its pneumonic superinfection and complicating inflammation?
Scand J Immunol, 93 (1), e12937
DOI 10.1111/sji.12937, PubMed 32657436

Hetland G, Tangen JM, Mahmood F, Mirlashari MR, Nissen-Meyer LSH, Nentwich I, Therkelsen SP, Tjønnfjord GE, Johnson E (2020)
Antitumor, Anti-Inflammatory and Antiallergic Effects of Agaricus blazei Mushroom Extract and the Related Medicinal Basidiomycetes Mushrooms, Hericium erinaceus and Grifola frondosa: A Review of Preclinical and Clinical Studies
Nutrients, 12 (5)
DOI 10.3390/nu12051339, PubMed 32397163

Publications 2019

Johnson E, Therkelsen SP, Nentwich I, Nissen-Meyer LSH, Hetland G (2019)
IgE-sensitization to food and inhalant allergens in IBD patients compared with normal blood donors at Oslo University Hospital, Norway
Scand J Gastroenterol, 54 (9), 1107-1110
DOI 10.1080/00365521.2019.1663445, PubMed 31524013

Mahmood F, Hetland G, Nentwich I, Mirlashari MR, Ghiasvand R, Nissen-Meyer LSH (2019)
Agaricus blazei-Based Mushroom Extract Supplementation to Birch Allergic Blood Donors: A Randomized Clinical Trial
Nutrients, 11 (10)
DOI 10.3390/nu11102339, PubMed 31581605

Publications 2017

Tangen JM, Holien T, Mirlashari MR, Misund K, Hetland G (2017)
Cytotoxic Effect on Human Myeloma Cells and Leukemic Cells by the Agaricus blazei Murill Based Mushroom Extract, Andosan™
Biomed Res Int, 2017, 2059825
DOI 10.1155/2017/2059825, PubMed 29238712

Publications 2016

Hetland G, Eide DM, Tangen JM, Haugen MH, Mirlashari MR, Paulsen JE (2016)
The Agaricus blazei-Based Mushroom Extract, Andosan™, Protects against Intestinal Tumorigenesis in the A/J Min/+ Mouse
PLoS One, 11 (12), e0167754
DOI 10.1371/journal.pone.0167754, PubMed 28002446

Therkelsen SP, Hetland G, Lyberg T, Lygren I, Johnson E (2016)
Effect of a Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSan™, on Symptoms, Fatigue and Quality of Life in Patients with Ulcerative Colitis in a Randomized Single-Blinded Placebo Controlled Study
PLoS One, 11 (3), e0150191
DOI 10.1371/journal.pone.0150191, PubMed 26933886

Therkelsen SP, Hetland G, Lyberg T, Lygren I, Johnson E (2016)
Effect of the Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSanTM, on Symptoms, Fatigue and Quality of Life in Patients with Crohn's Disease in a Randomized Single-Blinded Placebo Controlled Study
PLoS One, 11 (7), e0159288
DOI 10.1371/journal.pone.0159288, PubMed 27415795

Therkelsen SP, Hetland G, Lyberg T, Lygren I, Johnson E (2016)
Cytokine Levels After Consumption of a Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSan , in Patients with Crohn's Disease and Ulcerative Colitis in a Randomized Single-Blinded Placebo-Controlled Study
Scand J Immunol, 84 (6), 323-331
DOI 10.1111/sji.12476, PubMed 27588816

Publications 2015

Tangen JM, Tierens A, Caers J, Binsfeld M, Olstad OK, Trøseid AM, Wang J, Tjønnfjord GE, Hetland G (2015)
Immunomodulatory effects of the Agaricus blazei Murrill-based mushroom extract AndoSan in patients with multiple myeloma undergoing high dose chemotherapy and autologous stem cell transplantation: a randomized, double blinded clinical study
Biomed Res Int, 2015, 718539
DOI 10.1155/2015/718539, PubMed 25664323

Publications 2014

Berven L, Karppinen P, Hetland G, Samuelsen AB (2014)
The polar high molecular weight fraction of the Agaricus blazei Murill extract, AndoSan™, reduces the activity of the tumor-associated protease, legumain, in RAW 264.7 cells
J Med Food, 18 (4), 429-38
DOI 10.1089/jmf.2014.0018, PubMed 25136950

Publications 2012

Biedron R, Tangen JM, Maresz K, Hetland G (2012)
Agaricus blazei Murill - immunomodulatory properties and health benefits
Funct. Foods Health Dis., 2 (11), 428-447
DOI 10.31989/ffhd.v2i11.72

Johnson E, Førland DT, Hetland G, Sætre L, Olstad OK, Lyberg T (2012)
Effect of AndoSan™ on expression of adhesion molecules and production of reactive oxygen species in human monocytes and granulocytes in vivo
Scand J Gastroenterol, 47 (8-9), 984-92
DOI 10.3109/00365521.2012.660544, PubMed 22564240

Publications 2011

Førland DT, Johnson E, Saetre L, Lyberg T, Lygren I, Hetland G (2011)
Effect of an extract based on the medicinal mushroom Agaricus blazei Murill on expression of cytokines and calprotectin in patients with ulcerative colitis and Crohn's disease
Scand J Immunol, 73 (1), 66-75
DOI 10.1111/j.1365-3083.2010.02477.x, PubMed 21129005

Hetland G, Johnson E, Lyberg T, Kvalheim G (2011)
The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation
Adv Pharmacol Sci, 2011, 157015
DOI 10.1155/2011/157015, PubMed 21912538

Publications 2010

Bertelsen RJ, Instanes C, Granum B, Lødrup Carlsen KC, Hetland G, Carlsen KH, Mowinckel P, Løvik M (2010)
Gender differences in indoor allergen exposure and association with current rhinitis
Clin Exp Allergy, 40 (9), 1388-97
DOI 10.1111/j.1365-2222.2010.03543.x, PubMed 20545709

Publications 2009

Ellertsen LK, Hetland G (2009)
An extract of the medicinal mushroom Agaricus blazei Murill can protect against allergy
Clin Mol Allergy, 7, 6
DOI 10.1186/1476-7961-7-6, PubMed 19416507

Ellertsen LK, Storla DG, Diep LM, Brokstad KA, Wiker HG, Hetland G (2009)
Allergic sensitisation in tuberculosis patients at the time of diagnosis and following chemotherapy
BMC Infect Dis, 9, 100
DOI 10.1186/1471-2334-9-100, PubMed 19558655

Førland DT, Johnson E, Tryggestad AM, Lyberg T, Hetland G (2009)
An extract based on the medicinal mushroom Agaricus blazei Murill stimulates monocyte-derived dendritic cells to cytokine and chemokine production in vitro
Cytokine, 49 (3), 245-50
DOI 10.1016/j.cyto.2009.09.002, PubMed 20036142

Johnson E, Førland DT, Saetre L, Bernardshaw SV, Lyberg T, Hetland G (2009)
Effect of an extract based on the medicinal mushroom Agaricus blazei murill on release of cytokines, chemokines and leukocyte growth factors in human blood ex vivo and in vivo
Scand J Immunol, 69 (3), 242-50
DOI 10.1111/j.1365-3083.2008.02218.x, PubMed 19281536

Publications 2008

Ellertsen LK, Hetland G, Løvik M (2008)
Specific IgE to respiratory allergens and IgG antibodies to Toxoplasma gondii and Streptococcus pneumoniae in Norwegian military recruits
Scand J Immunol, 67 (5), 496-500
DOI 10.1111/j.1365-3083.2008.02090.x, PubMed 18312484

Herseth J, Refsnes M, Låg M, Hetland G, Schwarze P (2008)
IL-1beta as a determinant in silica-induced cytokine responses in monocyte-endothelial cell co-cultures
Hum Exp Toxicol, 27 (5), 387-99
DOI 10.1177/0960327108094610, PubMed 18715885

Hetland G, Johnson E, Lyberg T, Bernardshaw S, Tryggestad AM, Grinde B (2008)
Effects of the medicinal mushroom Agaricus blazei Murill on immunity, infection and cancer
Scand J Immunol, 68 (4), 363-70
DOI 10.1111/j.1365-3083.2008.02156.x, PubMed 18782264

Publications 2007

Bernardshaw S, Lyberg T, Hetland G, Johnson E (2007)
Effect of an extract of the mushroom Agaricus blazei Murill on expression of adhesion molecules and production of reactive oxygen species in monocytes and granulocytes in human whole blood ex vivo
APMIS, 115 (6), 719-25
DOI 10.1111/j.1600-0463.2007.apm_619.x, PubMed 17550380

Rydjord B, Marton JH, Strømsnes H, Granum B, Bolle R, Nystad W, Hetland G (2007)
Mould-specific immunoglobulin antibodies quantified by flow cytometry reflect mould exposure in Norwegian children
Clin Exp Allergy, 38 (3), 430-7
DOI 10.1111/j.1365-2222.2007.02905.x, PubMed 18167125

Rydjord B, Namork E, Nygaard UC, Wiker HG, Hetland G (2007)
Quantification and characterisation of IgG binding to mould spores by flow cytometry and scanning electron microscopy
J Immunol Methods, 323 (2), 123-31
DOI 10.1016/j.jim.2007.04.001, PubMed 17490674

Publications 2006

Bernardshaw S, Hetland G, Grinde B, Johnson E (2006)
An extract of the mushroom Agaricus blazei Murill protects against lethal septicemia in a mouse model of fecal peritonitis
Shock, 25 (4), 420-5
DOI 10.1097/01.shk.0000209526.58614.92, PubMed 16670646

Grinde B, Hetland G, Johnson E (2006)
Effects on gene expression and viral load of a medicinal extract from Agaricus blazei in patients with chronic hepatitis C infection
Int Immunopharmacol, 6 (8), 1311-4
DOI 10.1016/j.intimp.2006.04.005, PubMed 16782544

Publications 2005

Bernardshaw S, Hetland G, Ellertsen LK, Tryggestad AM, Johnson E (2005)
An extract of the medicinal mushroom Agaricus blazei Murill differentially stimulates production of pro-inflammatory cytokines in human monocytes and human vein endothelial cells in vitro
Inflammation, 29 (4-6), 147-53
DOI 10.1007/s10753-006-9010-2, PubMed 17091395

Bernardshaw S, Johnson E, Hetland G (2005)
An extract of the mushroom Agaricus blazei Murill administered orally protects against systemic Streptococcus pneumoniae infection in mice
Scand J Immunol, 62 (4), 393-8
DOI 10.1111/j.1365-3083.2005.01667.x, PubMed 16253127

Ellertsen LK, Hetland G, Johnson E, Grinde B (2005)
Effect of a medicinal extract from Agaricus blazei Murill on gene expression in a human monocyte cell line as examined by microarrays and immuno assays
Int Immunopharmacol, 6 (2), 133-43
DOI 10.1016/j.intimp.2005.07.007, PubMed 16399618

Ellertsen LK, Wiker HG, Egeberg NT, Hetland G (2005)
Allergic sensitisation in tuberculosis and leprosy patients
Int Arch Allergy Immunol, 138 (3), 217-24
DOI 10.1159/000088722, PubMed 16210860

Instanes C, Hetland G, Berntsen S, Løvik M, Nafstad P (2005)
Allergens and endotoxin in settled dust from day-care centers and schools in Oslo, Norway
Indoor Air, 15 (5), 356-62
DOI 10.1111/j.1600-0668.2005.00381.x, PubMed 16108908

Instanes C, Ward MD, Hetland G (2005)
The fungal biopesticide Metarhizium anisopliae has an adjuvant effect on the allergic response to ovalbumin in mice
Toxicol Lett, 161 (3), 219-25
DOI 10.1016/j.toxlet.2005.09.006, PubMed 16216451

Rydjord B, Hetland G, Wiker HG (2005)
Immunoglobulin G antibodies against environmental moulds in a Norwegian healthy population shows a bimodal distribution for Aspergillus versicolor
Scand J Immunol, 62 (3), 281-8
DOI 10.1111/j.1365-3083.2005.01672.x, PubMed 16179015

Publications 2004

Bernardshaw S, Johnson E, Hetland G (2004)
Extract of the mushroom Agaricus blazei Murill administered orally protects against systemic Streptococcus pneumoniae infection in mice
IMMUNOLOGY 2004: GENOMIC ISSUES, IMMUNE SYSTEM ACTIVATION AND ALLERGY, 473-477

Instanes C, Hetland G (2004)
Deoxynivalenol (DON) is toxic to human colonic, lung and monocytic cell lines, but does not increase the IgE response in a mouse model for allergy
Toxicology, 204 (1), 13-21
DOI 10.1016/j.tox.2004.05.011, PubMed 15369845

Instanes C, Ormstad H, Rydjord B, Wiker HG, Hetland G (2004)
Mould extracts increase the allergic response to ovalbumin in mice
Clin Exp Allergy, 34 (10), 1634-41
DOI 10.1111/j.1365-2222.2004.02076.x, PubMed 15479281

Publications 2003

Berge V, Langeggen H, Johnson E, Hetland G (2003)
Comparison of BTA Stat and enzyme immuno assay bladder tumor antigen in urine from patients with pathology in the urinary tract
In Scandinavian journal of urology and nephrology, Supplementum, Taylor & Francis, Oxford, 37(2003)suppl 214, s.48-9 abstract P14
BIBSYS 041732154

Langeggen H, Namork E, Johnson E, Hetland G (2003)
HUVEC take up opsonized zymosan particles and secrete cytokines IL-6 and IL-8 in vitro
FEMS Immunol Med Microbiol, 36 (1-2), 55-61
DOI 10.1016/S0928-8244(03)00033-6, PubMed 12727366

Publications 2002

Hetland G, Sandven P (2002)
beta-1,3-Glucan reduces growth of Mycobacterium tuberculosis in macrophage cultures
FEMS Immunol Med Microbiol, 33 (1), 41-5
DOI 10.1111/j.1574-695X.2002.tb00570.x, PubMed 11985967

Langeggen H, Berge KE, Johnson E, Hetland G (2002)
Human umbilical vein endothelial cells express complement receptor 1 (CD35) and complement receptor 4 (CD11c/CD18) in vitro
Inflammation, 26 (3), 103-10
DOI 10.1023/a:1015585530204, PubMed 12083416

Publications 2001

Hetland G, Granum B, Groeng EC, Løvik M (2001)
Leptin does not influence the IgE response to ovalbumin in mice
Clin Immunol, 101 (1), 8-11
DOI 10.1006/clim.2001.5087, PubMed 11580221

Langeggen H, Berge KE, Macor P, Fischetti F, Tedesco F, Hetland G, Berg K, Johnson E (2001)
Detection of mRNA for the terminal complement components C5, C6, C8 and C9 in human umbilical vein endothelial cells in vitro
APMIS, 109 (1), 73-8
DOI 10.1111/j.1600-0463.2001.tb00016.x, PubMed 11297196

Langeggen H, Johnson E, Hetland G (2001)
Effects of C5a and FMLP on interleukin-8 production and proliferation of human umbilical vein endothelial cells
Inflammation, 25 (2), 83-9
DOI 10.1023/a:1007162320882, PubMed 11321363

Publications 2000

Hetland G, Namork E, Schwarze PE, Aase A (2000)
Mechanism for uptake of silica particles by monocytic U937 cells
Hum Exp Toxicol, 19 (7), 412-9
DOI 10.1191/096032700678816106, PubMed 11002391

Hetland G, Ohno N, Aaberge IS, Lovik M (2000)
Protective effect of beta-glucan against systemic Streptococcus pneumoniae infection in mice
FEMS Immunol Med Microbiol, 27 (2), 111-6
DOI 10.1111/j.1574-695X.2000.tb01420.x, PubMed 10640605

Hetland G, Samuelsen AB, Løvik M, Paulsen BS, Aaberge IS, Groeng EC, Michaelsen TE (2000)
Protective effect of Plantago major L. Pectin polysaccharide against systemic Streptococcus pneumoniae infection in mice
Scand J Immunol, 52 (4), 348-55
DOI 10.1046/j.1365-3083.2000.00793.x, PubMed 11013005

Johnson E, Langeggen H, Hetland G (2000)
Concentrations of leucocyte-associated chemotaxin C5a correlate with the mobilisation of polymorphonuclear leucocytes during operations for rectal cancer
Eur J Surg, 166 (2), 159-64
DOI 10.1080/110241500750009528, PubMed 10724495

Ormstad H, Groeng EC, Løvik M, Hetland G (2000)
The fungal cell wall component beta-1,3-glucan has an adjuvant effect on the allergic response to ovalbumin in mice
J Toxicol Environ Health A, 61 (1), 55-67
DOI 10.1080/00984100050116780, PubMed 10990163

Publications 1999

Hetland G (1999)
[More about the 2-year internship and residency]
Tidsskr Nor Laegeforen, 119 (9), 1339-40
PubMed 10327867

Publications 1998

Baksaas ST, Videm V, Mollnes TE, Tølløfsrud S, Hetland G, Pedersen T, Svennevig JL (1998)
Leucocyte filtration during cardiopulmonary bypass hardly changed leucocyte counts and did not influence myeloperoxidase, complement, cytokines or platelets
Perfusion, 13 (6), 429-36
DOI 10.1177/026765919801300606, PubMed 9881390

Hetland G (1998)
[Internship, family physicians and the EEC agreement]
Tidsskr Nor Laegeforen, 118 (26), 4123
PubMed 9844522

Hetland G, Løvik M, Wiker HG (1998)
Protective effect of beta-glucan against mycobacterium bovis, BCG infection in BALB/c mice
Scand J Immunol, 47 (6), 548-53
DOI 10.1046/j.1365-3083.1998.00350.x, PubMed 9652822

Hetland G, Mollnes TE, Bergh K, Høgåsen K, Bergerud UE, Solheim BG (1998)
Effect of filtration and storage of platelet concentrates on the production of the chemotaxins C5a, interleukin 8, tumor necrosis factor alpha, and leukotriene B4
Transfusion, 38 (1), 16-23
DOI 10.1046/j.1537-2995.1998.38198141493.x, PubMed 9482389

Hetland G, Pfeifer PH, Hugli TE (1998)
Processing of C5a by human polymorphonuclear leukocytes
J Leukoc Biol, 63 (4), 456-62
DOI 10.1002/jlb.63.4.456, PubMed 9544575

Hetland G, Solheim BG (1998)
Quality of platelet concentrates Reply
Transfusion, 38 (8), 799-800

Hetland G, Talgö GJ, Fagerhol MK (1998)
Chemotaxins C5a and fMLP induce release of calprotectin (leucocyte L1 protein) from polymorphonuclear cells in vitro
Mol Pathol, 51 (3), 143-8
DOI 10.1136/mp.51.3.143, PubMed 9850337

Hetland G, Wiker HG, Høgåsen K, Hamasur B, Svenson SB, Harboe M (1998)
Involvement of antilipoarabinomannan antibodies in classical complement activation in tuberculosis
Clin Diagn Lab Immunol, 5 (2), 211-8
DOI 10.1128/CDLI.5.2.211-218.1998, PubMed 9521145

Publications 1997

Hetland G (1997)
Cytotoxic effect of dibutyryl cAMP, phorbol-12-myristate-13-acetate and lipopolysaccharide, but not interferon-gamma, on promonocytic cell lines in vitro
Anticancer Drugs, 8 (6), 618-22
DOI 10.1097/00001813-199707000-00010, PubMed 9300577

Hetland G (1997)
Both plasma- and leukocyte-associated C5a are essential for assessment of C5a generation in vivo
Society of Thoracic Surgeons, [New York], Bl. [1076]-1080
BIBSYS 981784690

Hetland G (1997)
Effect of leukocyte-filtration and storage of platelet concentrates on complement activation and production of chemotaxins C5a, IL-8, TNFα and LTB4
[Karger], [Basel], Bl. 95.
BIBSYS 982303211

Hetland G, Moen O, Bergh K, Högäsen K, Hack CE, Mollnes TE, Fosse E (1997)
Both plasma- and leukocyte-associated C5a are essential for assessment of C5a generation in vivo
Ann Thorac Surg, 63 (4), 1076-80
DOI 10.1016/s0003-4975(96)01255-6, PubMed 9124908

Publications 1996

Hetland G, Hugli TE (1996)
Cytotoxic effect of radiolabeled C5a on U937 cells in vitro
Cancer Lett, 110 (1-2), 97-103
DOI 10.1016/s0304-3835(96)04467-9, PubMed 9018087

Publications 1995

Hetland G, Guinn K, Hugli TE (1995)
Of formyl peptide-toxin conjugates on myeloid cancer cell lines in vitro
Int. J. Immunother., 11 (3), 85-93

Publications 1994

Hetland G, del Zoppo GJ, Mori E, Thomas WS, Hugli TE (1994)
Uptake of C5a by polymorphonuclear leukocytes (PMNs) after focal cerebral ischemia. I. Effect of tirilazad mesylate intervention on C5a uptake by PMNs
Immunopharmacology, 27 (3), 191-8
DOI 10.1016/0162-3109(94)90015-9, PubMed 8071059

Hetland G, Wiker HG (1994)
Antigen 85C on Mycobacterium bovis, BCG and M. tuberculosis promotes monocyte-CR3-mediated uptake of microbeads coated with mycobacterial products
Immunology, 82 (3), 445-9
PubMed 7959881

Publications 1993

Hetland G, Mollnes TE, Garred P (1993)
The B chain, but not the A chain, of Ricinus communis activates human complement
Cancer Lett, 75 (1), 59-63
DOI 10.1016/0304-3835(93)90208-q, PubMed 8287382

Publications 1992

Berge V, Johnson E, Høgåsen K, Hetland G (1992)
Human umbilical vein endothelial cells synthesize S-protein (vitronectin) in vitro
Scand J Immunol, 36 (1), 119-23
DOI 10.1111/j.1365-3083.1992.tb02947.x, PubMed 1377399

Hetland G, Berntzen HB, Fagerhol MK (1992)
Levels of calprotectin (leukocyte L1 protein) during apheresis
Scand J Clin Lab Invest, 52 (6), 479-82
DOI 10.3109/00365519209090124, PubMed 1411260

Hetland G, Holme I, Strømme JH (1992)
Co-variation of alanine aminotransferase levels with relative weight in blood donors
Scand J Clin Lab Invest, 52 (1), 51-5
DOI 10.3109/00365519209085440, PubMed 1594888

Hetland G, Mollnes TE, Larsen J, Garred P (1992)
Biocompatibility of white cell filters as evaluated by complement activation
Transfusion, 32 (6), 557-61
DOI 10.1046/j.1537-2995.1992.32692367201.x, PubMed 1502709

Publications 1991

Hetland G, Garred P, Mollnes TE, Størvold G (1991)
The use of flow cytometry to detect the biosynthesis of complement components
J Immunol Methods, 140 (2), 167-71
DOI 10.1016/0022-1759(91)90367-o, PubMed 2066563

Hetland G, Mollnes TE, Garred P (1991)
Activation of complement during apheresis
Clin Exp Immunol, 84 (3), 535-8
PubMed 1904328

Johnson E, Hetland G (1991)
Human umbilical vein endothelial cells synthesize functional C3, C5, C6, C8 and C9 in vitro
Scand J Immunol, 33 (6), 667-71
DOI 10.1111/j.1365-3083.1991.tb02539.x, PubMed 2047760

Larsen J, Hetland G, Skaug K, Maeland A (1991)
[Viral hepatitis and blood transfusion]
Tidsskr Nor Laegeforen, 111 (7), 825-8
PubMed 1850559

Larsen J, Skaug K, Maeland A, Hetland G, Stoervold G (1991)
Infective, chronic carriers of hepatitis C virus among blood donors with no history of clinical hepatitis
Transfus Med, 1 (1), 13-6
DOI 10.1111/j.1365-3148.1991.tb00003.x, PubMed 9259821

Publications 1990

Garred P, Hetland G, Mollnes TE, Stoervold G (1990)
Synthesis of C3, C5, C6, C7, C8, and C9 by human fibroblasts
Scand J Immunol, 32 (5), 555-60
DOI 10.1111/j.1365-3083.1990.tb03196.x, PubMed 2270435

Hetland G, Garred P, Pettersen HB, Mollnes TE, Johnson E (1990)
S protein binds to serum-treated agarose beads independently of complement activation and the formation of the terminal complement complex on the beads
Clin Exp Immunol, 79 (3), 459-62
DOI 10.1111/j.1365-2249.1990.tb08112.x, PubMed 1690618

Hetland G, Skaug K, Larsen J, Maland A, Strømme JH, Størvold G (1990)
Prevalence of anti-HCV in Norwegian blood donors with anti-HBc or increased ALT levels
Transfusion, 30 (9), 776-9
DOI 10.1046/j.1537-2995.1990.30991048780.x, PubMed 2173175

Larsen J, Hetland G, Skaug K (1990)
Posttransfusion hepatitis B transmitted by blood from a hepatitis B surface antigen-negative hepatitis B virus carrier
Transfusion, 30 (5), 431-2
DOI 10.1046/j.1537-2995.1990.30590296376.x, PubMed 2360234

Pettersen HB, Johnson E, Garred P, Hetland G, Osen SS, Mollnes TE (1990)
Quantification of non-activated (native) complement component C9 synthesized by alveolar macrophages from patients with sarcoidosis
Scand J Immunol, 31 (5), 657-63
DOI 10.1111/j.1365-3083.1990.tb02816.x, PubMed 2189215

Pettersen HB, Johnson E, Mollnes TE, Garred P, Hetland G, Osen SS (1990)
Synthesis of complement by alveolar macrophages from patients with sarcoidosis
Scand J Immunol, 31 (1), 15-23
DOI 10.1111/j.1365-3083.1990.tb02738.x, PubMed 1689072

Publications 1989

Hetland G, Pettersen HB, Mollnes TE, Johnson E (1989)
S-protein is synthesized by human monocytes and macrophages in vitro
Scand J Immunol, 29 (1), 15-21
DOI 10.1111/j.1365-3083.1989.tb01094.x, PubMed 2466326

Publications 1988

Hetland G (1988)
[Immunity against HIV infection]
Tidsskr Nor Laegeforen, 108 (26), 2165-7
PubMed 3264628

Hetland G (1988)
[Perforines. The killer proteins of the lymphocytes]
Tidsskr Nor Laegeforen, 108 (28), 2394-6
PubMed 3264631

Hetland G, Bungum L (1988)
Human peritoneal macrophages. Production in vitro of the active terminal complement components C5 to C9 and a functional alternative pathway of complement. Brief report
APMIS, 96 (1), 89-92
DOI 10.1111/j.1699-0463.1988.tb05273.x, PubMed 3345254

Hetland G, Johnson E, Eskeland T (1988)
[Biosynthesis of complement in mononuclear phagocytes]
Tidsskr Nor Laegeforen, 108 (1), 32-4
PubMed 3353902

Johnson E, Hetland G (1988)
A sensitive method to detect synthesis of the functional classical, alternative and terminal pathway of complement by cells cultured in vitro
Scand J Clin Lab Invest, 48 (3), 223-31
DOI 10.3109/00365518809167488, PubMed 3287591

Johnson E, Hetland G (1988)
Mononuclear phagocytes have the potential to synthesize the complete functional complement system
Scand J Immunol, 27 (5), 489-93
DOI 10.1111/j.1365-3083.1988.tb02375.x, PubMed 3287594

Publications 1987

Hetland G (1987)
Biosynthesis of complement in mononuclear phagocytes
[G. Hetland], Tromsø, 1 b. (fl.pag.)
BIBSYS 883027607

Hetland G, Eskeland T (1987)
Mouse peritoneal macrophages cultured serum-free deposit complement on IgM-coated sheep erythrocytes in vitro
Acta Pathol Microbiol Immunol Scand C, 95 (1), 15-20
DOI 10.1111/j.1699-0463.1987.tb00003.x, PubMed 3554893

Hetland G, Johnson E, Eskeland T (1987)
Formation of the membrane attack complex of complement (MAC) on erythrocytes from monocyte-produced terminal complement components
Scand J Immunol, 25 (6), 571-7
DOI 10.1111/j.1365-3083.1987.tb01083.x, PubMed 3602934

Hetland G, Johnson E, Røyset P, Eskeland T (1987)
Human alveolar macrophages and monocytes generate the functional classical pathway of complement in vitro
Acta Pathol Microbiol Immunol Scand C, 95 (3), 117-22
DOI 10.1111/j.1699-0463.1987.tb00018.x, PubMed 3630715

Pettersen HB, Johnson E, Hetland G (1987)
Human alveolar macrophages synthesize active complement components C6, C7, and C8 in vitro
Scand J Immunol, 25 (6), 567-70
DOI 10.1111/j.1365-3083.1987.tb01082.x, PubMed 3602933

Publications 1986

Hetland G, Eskeland T (1986)
Formation of the functional alternative pathway of complement by human monocytes in vitro as demonstrated by phagocytosis of agarose beads
Scand J Immunol, 23 (3), 301-8
DOI 10.1111/j.1365-3083.1986.tb01971.x, PubMed 3952470

Hetland G, Johnson E, Falk RJ, Eskeland T (1986)
Synthesis of complement components C5, C6, C7, C8 and C9 in vitro by human monocytes and assembly of the terminal complement complex
Scand J Immunol, 24 (4), 421-8
DOI 10.1111/j.1365-3083.1986.tb02130.x, PubMed 3764345

Hetland G, Johnson E, Aasebø U (1986)
Human alveolar macrophages synthesize the functional alternative pathway of complement and active C5 and C9 in vitro
Scand J Immunol, 24 (5), 603-8
DOI 10.1111/j.1365-3083.1986.tb02176.x, PubMed 3787189

Johnson E, Larsen T, Hetland G (1986)
Phagocytosis of agarose beads by receptors for C3b (CR1) and iC3b (CR3) on human alveolar macrophages cultured on fibronectin in vitro. A scanning electron microscopic study
Scand J Immunol, 24 (6), 653-60
DOI 10.1111/j.1365-3083.1986.tb02184.x, PubMed 2948272

Publications 1985

Björkman A, Brohult J, Willcox M, Pehrson PO, Rombo L, Hedman P, Hetland G, Kollie E, Hanson AP, Bengtsson E (1985)
Malaria control by chlorproguanil. I. Clinical effects and susceptibility of Plasmodium falciparum in vivo after seven years of monthly chlorproguanil administration to children in a Liberian village
Ann Trop Med Parasitol, 79 (6), 597-601
PubMed 3914861

Björkman A, Rombo L, Hetland G, Willcox M, Hanson AP (1985)
Susceptibility of Plasmodium falciparum to chloroquine in northern Liberia after 20 years of chemosuppression and therapy
Ann Trop Med Parasitol, 79 (6), 603-6
DOI 10.1080/00034983.1985.11811967, PubMed 3914862