Gudrun Høiseth
- Head of Research; MD; PhD
- +47 23 01 30 26
Publications 2023
Kapittel 49 LAR-behandling med metadon og buprenorfin
In Lærebok i rettsmedisin , Gyldendahl, Oslo, 4
PublikaID 458, ISBN 9788205584167
Publications 2022
The alcohol marker phosphatidylethanol is closely related to AST, GGT, ferritin and HDL-C
Basic Clin. Pharmacol. Toxicol., 130 (1), 182-190
DOI 10.1111/bcpt.13662
Frequency of postmortem ethanol formation in blood, urine and vitreous humor-Improving diagnostic accuracy with the use of ethylsulphate and putrefactive alcohols
Forensic Sci.Int., 331, 111152
DOI 10.1016/j.forsciint.2021.111152
Publications 2021
Comparison of the Diagnostic Value of Phosphatidylethanol and Carbohydrate-Deficient Transferrin as Biomarkers of Alcohol Consumption
Alcoholism (NY), 45 (1), 153-162
DOI 10.1111/acer.14503
Subjective symptoms and serum methadone concentrations: what should guide dose adjustments in methadone maintenance treatment? A naturalistic cohort study from Norway
Subst/ Abus. Treatment Prev. Pol., 16 (1), 39
DOI 10.1186/s13011-021-00367-w
Associations of Binge Drinking With the Risks of Ischemic Heart Disease and Stroke: A Study of Pooled Norwegian Health Surveys
Am. J. Epidemiol., 190 (8), 1592-1603
DOI 10.1093/aje/kwab063
A comparison of driving related skills impaired by ethanol and zopiclone
Traffic Inj. Prev., 22 (1), 26-31
DOI 10.1080/15389588.2020.1849643
Relationship between betahydroxybutyrate (BHB) and acetone concentrations in postmortem blood and cause of death
Forensic Sci.Int., 321, 110726
DOI 10.1016/j.forsciint.2021.110726
Impact of age and gender on paliperidone exposure in patients after administration of long-acting injectable formulations-an observational study using blood samples from 1223 patients
Eur. J. Clin. Pharmacol., 77 (8), 1201-1208
DOI 10.1007/s00228-021-03114-z
Impact of age andCYP2D6genotype on exposure of zuclopenthixol in patients using long-acting injectable versus oral formulation-an observational study including 2044 patients
Eur. J. Clin. Pharmacol., 77 (2), 215-221
DOI 10.1007/s00228-020-03002-y
Alcohol Consumption, HDL-Cholesterol and Incidence of Colon and Rectal Cancer: A Prospective Cohort Study Including 250,010 Participants
Alcohol Alcohol., 56 (6), 718-725
DOI 10.1093/alcalc/agab007
Impact of CYP2D6 on serum concentrations of flupentixol, haloperidol, perphenazine and zuclopenthixol
Br. J. Clin. Pharmacol., 87 (5), 2228-2235
DOI 10.1111/bcp.14626
Publications 2020
Prenatal exposure to methadone or buprenorphine and long-term outcomes: A meta-analysis
Early Hum. Dev., 143, 104997
DOI 10.1016/j.earlhumdev.2020.104997
Rate of elimination of gamma-hydroxybutyrate from blood determined by analysis of two consecutive samples from apprehended drivers in Norway
Forensic Sci.Int., 314, 110374
DOI 10.1016/j.forsciint.2020.110374
Oral Fluid to Blood Concentration Ratios of Different Psychoactive Drugs in Samples from Suspected Drugged Drivers
Ther. Drug Monit., 42 (5), 795-800
DOI 10.1097/FTD.0000000000000760
Association of coincident self-reported mental health problems and alcohol intake with all-cause and cardiovascular disease mortality: A Norwegian pooled population analysis
PLos Med., 17 (2), e1003030
DOI 10.1371/journal.pmed.1003030
The Relationship Between Ingested Dose of Ethanol and Amount of Ethyl Glucuronide Formed in Blood
J. Anal. Toxicol., 44 (8), 861-863
DOI 10.1093/jat/bkaa090
Blood Concentrations of Designer Benzodiazepines: Relation to Impairment and Findings in Forensic Cases
J. Anal. Toxicol., 44 (8), 905-914
DOI 10.1093/jat/bkaa043
Evaluating the hip-flask defence using analytical data from ethanol and ethyl glucuronide. A comparison of two models
Forensic Sci.Int., 316, 110409
DOI 10.1016/j.forsciint.2020.110409
Drug use may cause unexpected findings during urinary drug analysis
Tidsskr. Nor. Laegeforen., 140 (13), 1375
Impact of age and CYP2D6 genetics on exposure of aripiprazole and dehydroaripiprazole in patients using long-acting injectable versus oral formulation: relevance of poor and intermediate metabolizer status
Eur. J. Clin. Pharmacol., 76 (1), 41-49
DOI 10.1007/s00228-019-02768-0
Publications 2019
Detection of Drugs in Simultaneously Collected Samples of Oral Fluid and Blood
J. Anal. Toxicol., 43 (3), 228-232
DOI 10.1093/jat/bky079
Detection Time of Oxazepam and Zopiclone in Urine and Oral Fluid after Experimental Oral Dosing
J. Anal. Toxicol., 43 (5), 369-377
DOI 10.1093/jat/bky083
Hair EtG: Alterations in segment levels accompanying hair growth
Drug Test. Anal., 11 (1), 112-118
DOI 10.1002/dta.2474
Dynamic assessment of the pupillary reflex in patients on high-dose opioids
Scand. J. Pain, 19 (3), 465-471
DOI 10.1515/sjpain-2019-0032
An Experimental Study of Diazepam and Alprazolam Kinetics in Urine and Oral Fluid Following Single Oral Doses
J. Anal. Toxicol., 43 (2), 104-111
DOI 10.1093/jat/bky062
Prescribing antipsychotics to the elderly living at home 2006-2018
Tidsskr. Nor. Laegeforen., 139 (16), 1554-1558
The Effect of Valproic Acid on Olanzapine Serum Concentration A Study Including 2791 Patients Treated With Olanzapine Tablets or Long-Acting Injections
J. Clin. Psychopharmacol., 39 (6), 561-566
DOI 10.1097/JCP.0000000000001126
Publications 2018
Life course socioeconomic position, alcohol drinking patterns in midlife, and cardiovascular mortality: Analysis of Norwegian population-based health surveys
PLos Med., 15 (1), e1002476
DOI 10.1371/journal.pmed.1002476
Fatal Adverse Event with Dabigatran in Elderly Patient with Reduced Kidney Function
Basic Clin. Pharmacol. Toxicol., 123 (2), 221-226
DOI 10.1111/bcpt.12985
The Appearance, Taste, and Concentrations of Zolpidem Dissolved in Still Water and Carbonated Beverages
J. Forensic Sci., 63 (3), 911-914
DOI 10.1111/1556-4029.13604
Is Hair Analysis Useful in Postmortem Cases?
J. Anal. Toxicol., 42 (1), 49-54
DOI 10.1093/jat/bkx077
A fatal blood concentration of 5-APB
Forensic Sci.Int., 291, E1-E3
DOI 10.1016/j.forsciint.2018.08.044
Can measurements of heroin metabolites in post-mortem matrices other than peripheral blood indicate if death was rapid or delayed?
Forensic Sci.Int., 290, 121-128
DOI 10.1016/j.forsciint.2018.06.041
Metabolites of Heroin in Several Different Post-mortem Matrices
J. Anal. Toxicol., 42 (5), 311-320
DOI 10.1093/jat/bky002
Age Impacts Olanzapine Exposure Differently During Use of Oral Versus Long-Acting Injectable Formulations: An Observational Study Including 8,288 Patients
J. Clin. Psychopharmacol., 38 (6), 570-576
DOI 10.1097/JCP.0000000000000961
Publications 2017
Ethyl Glucuronide Elimination Kinetics in Fingernails and Comparison to Levels in Hair
Alcohol Alcohol., 52 (5), 580-586
DOI 10.1093/alcalc/agx035
THC and CBD in blood samples and seizures in Norway: Does CBD affect THC-induced impairment in apprehended subjects?
Forensic Sci.Int., 276, 12-17
DOI 10.1016/j.forsciint.2017.04.006
Zopiclone concentrations in oral fluid and blood after, administration of therapeutic doses of zopiclone
Forensic Sci.Int., 278, 177-183
DOI 10.1016/j.forsciint.2017.07.004
Prevalence and concentrations of drugs in older suspected drugged drivers
Traffic Inj. Prev., 18 (3), 231-236
DOI 10.1080/15389588.2016.1247209
Impairment due to alcohol, tetrahydrocannabinol, and benzodiazepines in impaired drivers compared to experimental studies
Traffic Inj. Prev., 18 (3), 244-250
DOI 10.1080/15389588.2016.1201205
Urinary Kinetics of Heroin Metabolites in Pigs Shortly After Intake
J. Anal. Toxicol., 41 (5), 451-454
DOI 10.1093/jat/bkx017
A literature review of blood concentrations of new psychoactive substances classified as phenethylamines, aminoindanes, arylalkylamines, arylcyclohexylamines, and indolalkylamines
Forensic Sci.Int., 276, 120-125
DOI 10.1016/j.forsciint.2017.02.024
Combined Effect of CYP2B6 Genotype and Other Candidate Genes on a Steady-State Serum Concentration of Methadone in Opioid Maintenance Treatment
Ther. Drug Monit., 39 (5), 550-555
DOI 10.1097/FTD.0000000000000437
Publications 2016
Levels of Hair Ethyl Glucuronide in Patients with Decreased Kidney Function: Possibility of Misclassification of Social Drinkers
Alcoholism (NY), 40 (3), 451-456
DOI 10.1111/acer.12970
Pharmacokinetics of heroin and its metabolites in vitreous humor and blood in a living pig model
Forensic Toxicol., 34 (2), 277-285
DOI 10.1007/s11419-016-0315-z
Blood concentrations of new designer benzodiazepines in forensic cases
Forensic Sci.Int., 268, 35-38
DOI 10.1016/j.forsciint.2016.09.006
Ethanol elimination rates at low concentrations based on two consecutive blood samples
Forensic Sci.Int., 266, 191-196
DOI 10.1016/j.forsciint.2016.05.039
Cohort Profile Update: The Norwegian Mother and Child Cohort Study (MoBa)
Int. J. Epidemiol., 45 (2), 382-388
DOI 10.1093/ije/dyw029
Correlates of major medication side effects interfering with daily performance: results from a cross-sectional cohort study of older psychiatric patients
Int. Psychogeriatr., 28 (2), 331-340
DOI 10.1017/S1041610215001544
Publications 2015
Prevalence of Ethyl Glucuronide and Ethyl Sulphate Among Patients Injured When Driving or at Work
Alcohol Alcohol., 50 (1), 68-73
DOI 10.1093/alcalc/agu070
Rapport om konsekvenser for fosteret/barnet ved bruk av rusmidler/avhengighetsskapende legemidler i svangerskapet
Helsedirektoratet
PublikaID 460
Evaluation of the hip-flask defence by determination of ethyl glucuronide and ethyl sulphate concentrations in blood
Forensic Sci.Int., 257, 398-402
DOI 10.1016/j.forsciint.2015.10.017
Alcohol Hangover as a Cause of Impairment in Apprehended Drivers
Traffic Inj. Prev., 16 (4), 323-328
DOI 10.1080/15389588.2014.938324
Effect of CYP2B6*6 on Steady-State Serum Concentrations of Bupropion and Hydroxybupropion in Psychiatric Patients: A Study Based on Therapeutic Drug Monitoring Data
Ther. Drug Monit., 37 (5), 589-593
DOI 10.1097/FTD.0000000000000183
Has Previous Abuse of Flunitrazepam Been Replaced by Clonazepam?
Eur. Addict. Res., 21 (4), 217-221
DOI 10.1159/000377628
A fatal intoxication with phenazone (antipyrine)
Forensic Sci.Int., 248, E13-E15
DOI 10.1016/j.forsciint.2015.01.001
Publications 2014
Impairment due to amphetamines and benzodiazepines, alone and in combination
Drug Alcohol Depend., 145, 174-179
DOI 10.1016/j.drugalcdep.2014.10.013
Long-term stability of morphine, codeine, and 6-acetylmorphine in real-life whole blood samples, stored at -20 degrees C
Forensic Sci.Int., 239, 6-10
DOI 10.1016/j.forsciint.2014.03.008
Genetic variants in loci 1p13 and 9p21 and fatal coronary heart disease in a Norwegian case-cohort study
Mol. Biol. Rep., 41 (5), 2733-2743
DOI 10.1007/s11033-014-3096-7
Assistance of ethyl glucuronide and ethyl sulfate in the interpretation of postmortem ethanol findings
Int. J. Legal Med., 128 (5), 765-770
DOI 10.1007/s00414-014-1031-z
Pharmacokinetic interactions between ethanol and heroin: A study on post-mortem cases
Forensic Sci.Int., 242, 127-134
DOI 10.1016/j.forsciint.2014.06.032
Psychotropic medication in geriatric psychiatric patients: use and unreported use in relation to serum concentrations
Eur. J. Clin. Pharmacol., 70 (9), 1139-1145
DOI 10.1007/s00228-014-1720-z
Changes in Cognitive Function during Psychogeriatric Treatment in Relation to Benzodiazepine Cessation
Pharmacopsychiatry, 47 (4-5), 145-150
DOI 10.1055/s-0034-1381982
Publications 2013
Divergent associations of drinking frequency and binge consumption of alcohol with mortality within the same cohort
J. Epidemiol. Community Health, 67 (4), 350-357
DOI 10.1136/jech-2012-201564
Less glucuronidation of morphine in the presence of ethanol in vivo
Eur. J. Clin. Pharmacol., 69 (9), 1683-1687
DOI 10.1007/s00228-013-1533-5
Benzodiazepines in Geriatric Psychiatry What Doctors Report and What Patients Actually Use
Drugs Aging, 30 (2), 113-118
DOI 10.1007/s40266-012-0045-9
Is ADH1C genotype relevant for the cardioprotective effect of alcohol?
Alcohol, 47 (2), 81-84
DOI 10.1016/j.alcohol.2012.12.005
Higher Levels of Hair Ethyl Glucuronide in Patients with Decreased Kidney Function
Alcoholism (NY), 37 1, E14-E16
DOI 10.1111/j.1530-0277.2012.01882.x
A Clinical Study of the Cognitive Effects of Benzodiazepines in Psychogeriatric Patients
Pharmacopsychiatry, 46 (6), 209-213
DOI 10.1055/s-0033-1349131
Publications 2012
CYP2C19 genetics in fatal carisoprodol intoxications
Eur. J. Clin. Pharmacol., 68 (11), 1561-1565
DOI 10.1007/s00228-012-1278-6
Prolonged Urinary Detection Times of EtG and EtS in Patients with Decreased Renal Function
Alcoholism (NY), 36 (7), 1148-1151
DOI 10.1111/j.1530-0277.2011.01713.x
Publications 2011
Controlling for High-Density Lipoprotein Cholesterol Does Not Affect the Magnitude of the Relationship Between Alcohol and Coronary Heart Disease
Circulation, 124 (21), 2296-2302
DOI 10.1161/CIRCULATIONAHA.111.036491
Publications 2010
Practical use of ethyl glucuronide and ethyl sulfate in postmortem cases as markers of antemortem alcohol ingestion
Int. J. Legal Med., 124 (2), 143-148
DOI 10.1007/s00414-009-0393-0
Levels of Ethyl Glucuronide and Ethyl Sulfate in Oral Fluid, Blood, and Urine After Use of Mouthwash and Ingestion of Nonalcoholic Wine
J. Anal. Toxicol., 34 (2), 84-88
DOI 10.1093/jat/34.2.84
Ethyl Glucuronide Concentrations in Oral Fluid, Blood, and Urine After Volunteers Drank 0.5 and 1.0 g/kg Doses of Ethanol
J. Anal. Toxicol., 34 (6), 319-324
DOI 10.1093/jat/34.6.319
Publications 2009
The Effect of Scheduling and Withdrawal of Carisoprodol on Prevalence of Intoxications with the Drug
Basic Clin. Pharmacol. Toxicol., 105 (5), 345-349
DOI 10.1111/j.1742-7843.2009.00459.x
Ethyl Glucuronide in Hair Compared With Traditional Alcohol Biomarkers-A Pilot Study of Heavy Drinkers Referred to an Alcohol Detoxification Unit
Alcoholism (NY), 33 (5), 812-816
DOI 10.1111/j.1530-0277.2009.00900.x
Blood kinetics of ethyl glucuronide and ethyl sulphate in heavy drinkers during alcohol detoxification
Forensic Sci.Int., 188 (1-3), 52-56
DOI 10.1016/j.forsciint.2009.03.017
Serum/Whole Blood Concentration Ratio for Ethylglucuronide and Ethyl Sulfate
J. Anal. Toxicol., 33 (4), 208-211
DOI 10.1093/jat/33.4.208
Use of ethyl glucuronide and ethyl sulphate in forensic toxicology
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 839, 1 b. (flere pag.)
BIBSYS 093812582, ISBN 978-82-8072-347-5
Publications 2008
Comparison between the urinary alcohol markers EtG, EtS, and GTOL/5-HIAA in a controlled drinking experiment
Alcohol Alcohol., 43 (2), 187-191
DOI 10.1093/alcalc/agm175
Disappearance of ethyl glucuronide during heavy putrefaction
Forensic Sci.Int., 176 (2-3), 147-151
DOI 10.1016/j.forsciint.2007.08.002
In vitro formation of ethanol in autopsy samples containing fluoride ions
Int. J. Legal Med., 122 (1), 63-66
DOI 10.1007/s00414-007-0166-6
Acute intoxications with carisoprodol
Clin. Toxicol., 46 (4), 307-309
DOI 10.1080/15563650701476953
Publications 2007
A pharmacokinetic study of ethyl glucuronide in blood and urine: Applications to forensic toxicology
Forensic Sci.Int., 172 (2-3), 119-124
DOI 10.1016/j.forsciint.2007.01.005
Carisoprodol intoxications: a retrospective study of forensic autopsy material from 1992-2003
Int. J. Legal Med., 121 (5), 403-409
DOI 10.1007/s00414-006-0139-1
A study of ethyl glucuronide in post-mortem blood as a marker of ante-mortem ingestion of alcohol
Forensic Sci.Int., 165 (1), 41-45
DOI 10.1016/j.forsciint.2006.02.045
Publications 2006
Heroin-using drivers: importance of morphine and morphine-6-glucuronide on late clinical impairment
Eur. J. Clin. Pharmacol., 62 (11), 905-912
DOI 10.1007/s00228-006-0195-y