Publications 2024

Gregersen I, Kong XY, Kooijman S, Foyn H, Grannes H, Olsen MB, Lone AM, Yang K, Quiles-Jiménez A, Tran M, Øgaard J, Segers FM, Rashidi A, Sagen EL, Lauritzen KH, Pronk ACM, de Boer JF, Holven KB, Melum E, Aukrust P, Taskén K, Holm S, Rensen PCN, Dahl TB, Halvorsen B (2024)
T cells with increased responsiveness cause obesity in mice without diet intervention
iScience, 27 (4), 109471
DOI 10.1016/j.isci.2024.109471, PubMed 38551005

Kong XY, Lauritzen KH, Dahl TB, Holm S, Olsen MB, Skjelland M, Nielsen C, Michelsen AE, Ueland T, Aukrust P, Halvorsen B, Sandanger Ø (2024)
CD38 deficient mice are not protected from atherosclerosis
Biochem Biophys Res Commun, 705, 149734
DOI 10.1016/j.bbrc.2024.149734, PubMed 38430607

Olsen MB, Kong XY, Louwe MC, Lauritzen KH, Schanke Y, Kaasbøll OJ, Attramadal H, Øgaard J, Holm S, Aukrust P, Ryan L, Espevik T, Yurchenko M, Halvorsen B (2024)
SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice
Front Immunol, 15, 1383505
DOI 10.3389/fimmu.2024.1383505, PubMed 38686379

Olsen MB, Louwe MC, Yang K, Øgaard J, Dahl TB, Gregersen I, Alfsnes K, Lauritzen KH, Murphy SL, Ahmed MS, Aukrust P, Vinge LE, Yndestad A, Holven KB, Halvorsen B, Fosshaug LE (2024)
Continuous infusion of resolvin D2 in combination with Angiotensin-II show contrary effects on blood pressure and intracardiac artery remodeling
Biochem Biophys Res Commun, 733, 150706
DOI 10.1016/j.bbrc.2024.150706, PubMed 39305571

Publications 2023

Roman G, Stavik B, Lauritzen KH, Sandset PM, Harrison SP, Sullivan GJ, Chollet ME (2023)
"iPSC-derived liver organoids and inherited bleeding disorders: Potential and future perspectives"
Front Physiol, 14, 1094249
DOI 10.3389/fphys.2023.1094249, PubMed 36711019

Publications 2021

Lauritzen KH, Olsen MB, Ahmed MS, Yang K, Rinholm JE, Bergersen LH, Esbensen QY, Sverkeli LJ, Ziegler M, Attramadal H, Halvorsen B, Aukrust P, Yndestad A (2021)
Instability in NAD⁺ metabolism leads to impaired cardiac mitochondrial function and communication
Elife, 10
DOI 10.7554/eLife.59828, PubMed 34343089

Quiles-Jiménez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygård S, Scheffler K, Prins J, Van der Veer E, Øgaard JD, Fløisand Y, Jørgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552

Publications 2020

Ormel L, Lauritzen KH, Schreiber R, Kunzelmann K, Gundersen V (2020)
GABA, but Not Bestrophin-1, Is Localized in Astroglial Processes in the Mouse Hippocampus and the Cerebellum
Front Mol Neurosci, 13, 135
DOI 10.3389/fnmol.2020.00135, PubMed 32848599

Publications 2019

Guardia-Laguarta C, Liu Y, Lauritzen KH, Erdjument-Bromage H, Martin B, Swayne TC, Jiang X, Przedborski S (2019)
PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation
J Neurosci, 39 (36), 7074-7085
DOI 10.1523/JNEUROSCI.1691-18.2019, PubMed 31300519

Yang K, Lauritzen KH, Olsen MB, Dahl TB, Ranheim T, Ahmed MS, Attramadal H, Aukrust P, Halvorsen B, Nyman TA, Sandanger Ø, Yndestad A (2019)
Low Cellular NAD⁺ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442

Publications 2018

Hasan-Olive MM, Lauritzen KH, Ali M, Rasmussen LJ, Storm-Mathisen J, Bergersen LH (2018)
A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis
Neurochem Res, 44 (1), 22-37
DOI 10.1007/s11064-018-2588-6, PubMed 30027365

Publications 2016

Lauritzen KH, Hasan-Olive MM, Regnell CE, Kleppa L, Scheibye-Knudsen M, Gjedde A, Klungland A, Bohr VA, Storm-Mathisen J, Bergersen LH (2016)
A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain
Neurobiol Aging, 48, 34-47
DOI 10.1016/j.neurobiolaging.2016.08.005, PubMed 27639119

Publications 2015

Lauritzen KH, Kleppa L, Aronsen JM, Eide L, Carlsen H, Haugen ØP, Sjaastad I, Klungland A, Rasmussen LJ, Attramadal H, Storm-Mathisen J, Bergersen LH (2015)
Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure
Am J Physiol Heart Circ Physiol, 309 (3), H434-49
DOI 10.1152/ajpheart.00253.2014, PubMed 26055793

Morland C, Lauritzen KH, Puchades M, Holm-Hansen S, Andersson K, Gjedde A, Attramadal H, Storm-Mathisen J, Bergersen LH (2015)
The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain
J Neurosci Res, 93 (7), 1045-55
DOI 10.1002/jnr.23593, PubMed 25881750

Publications 2013

Lauritzen KH, Morland C, Puchades M, Holm-Hansen S, Hagelin EM, Lauritzen F, Attramadal H, Storm-Mathisen J, Gjedde A, Bergersen LH (2013)
Lactate receptor sites link neurotransmission, neurovascular coupling, and brain energy metabolism
Cereb Cortex, 24 (10), 2784-95
DOI 10.1093/cercor/bht136, PubMed 23696276

Publications 2012

Cheng C, Edin NF, Lauritzen KH, Aspmodal I, Christoffersen S, Jian L, Rasmussen LJ, Pettersen EO, Xiaoqun G, Bergersen LH (2012)
Alterations of monocarboxylate transporter densities during hypoxia in brain and breast tumour cells
Cell Oncol (Dordr), 35 (3), 217-27
DOI 10.1007/s13402-012-0081-9, PubMed 22700320

Publications 2011

Lauritzen KH (2011)
Mitochondrial DNA damage in forebrain neurons of mice
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 1090, 1 b. (flere pag.)
BIBSYS 111577616, ISBN 978-82-8264-151-7

Lauritzen KH, Cheng C, Wiksen H, Bergersen LH, Klungland A (2011)
Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses
DNA Repair (Amst), 10 (6), 639-53
DOI 10.1016/j.dnarep.2011.04.011, PubMed 21550321

Lauritzen KH, Dalhus B, Storm JF, Bjørås M, Klungland A (2011)
Modeling the impact of mitochondrial DNA damage in forebrain neurons and beyond
Mech Ageing Dev, 132 (8-9), 424-8
DOI 10.1016/j.mad.2011.02.006, PubMed 21354441

Publications 2010

Lauritzen KH, Moldestad O, Eide L, Carlsen H, Nesse G, Storm JF, Mansuy IM, Bergersen LH, Klungland A (2010)
Mitochondrial DNA toxicity in forebrain neurons causes apoptosis, neurodegeneration, and impaired behavior
Mol Cell Biol, 30 (6), 1357-67
DOI 10.1128/MCB.01149-09, PubMed 20065039

Publications 2006

Ringvoll J, Nordstrand LM, Vågbø CB, Talstad V, Reite K, Aas PA, Lauritzen KH, Liabakk NB, Bjørk A, Doughty RW, Falnes PØ, Krokan HE, Klungland A (2006)
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA
EMBO J, 25 (10), 2189-98
DOI 10.1038/sj.emboj.7601109, PubMed 16642038

Publications 2003

Lauritzen KH (2003)
Transcriptional regulation of the mitochondrial form of human uracil-DNA glycosylase
K. H. Lauritzen, [Trondheim], 92 bl.
BIBSYS 031583784