Tor Paaske Utheim
- Group leader; professor MD PhD
Education
- 2011: Ophthalmologist, Norway.
- 2010: PhD, Institute of Clinical Medicine, University of Oslo (UIO), Norway.
- 2001-2003: Internship, Sørlandet Hospital, Kristiansand and Eidfjord municipality, Norway.
- 1995-2001: Medical student, University of Oslo (UIO), Norway.
Affiliation
- Department of Medical Biochemistry, Oslo University Hospital - Ullevål, Norway.
- Department of Plastic and Reconstructive Surgery, Oslo University Hospital, Norway.
-
Institute of Oral Biology, Faculty of Dentistry, University of Oslo, Norway.
- Department of Life Sciences and Health, Oslo Metropolitan University, Norway.
- Department of Ophthalmology, Sørlandet Hospital Arendal,Norway.
- Department of Ophthalmology, Vestre Viken Hospital Trust, Norway.
- Department of Ophthalmology, Stavanger University Hospital, Norway.
- Department of Clinical Medicine, Faculty of Medicine, University of Bergen, Norway.
- The Norwegian Dry Eye Clinic, Oslo, Norway.
Links
- ResearchGate
- Profile at the University of Oslo
- Profile at the Oslo Metropolitan University
- Profile at the Norwegian Dry Eye Clinic, Oslo
NB: Visit our Gallery for group social events!
Publications 2024
Heritability of tear fluid cytokines in healthy twins
Ocul Surf, 32, 145-153
DOI 10.1016/j.jtos.2024.02.005, PubMed 38387783
Bioengineering strategy to promote CNS nerve growth and regeneration via chronic glutamate signaling
Acta Biomater, 190, 165-177
DOI 10.1016/j.actbio.2024.10.023, PubMed 39427766
Optimal transcorneal electrical stimulation parameters for preserving photoreceptors in a mouse model of retinitis pigmentosa
Neural Regen Res, 19 (11), 2543-2552
DOI 10.4103/1673-5374.392888, PubMed 38526290
Topical glaucoma medications - Possible implications on the meibomian glands
Acta Ophthalmol, 102 (7), 735-748
DOI 10.1111/aos.16728, PubMed 38822682
Purinergic agonists increase [Ca2+]i in rat conjunctival goblet cells through ryanodine receptor type 3
Am J Physiol Cell Physiol, 327 (3), C830-C843
DOI 10.1152/ajpcell.00291.2024, PubMed 39099424
The association between head injury and facial fracture treatment: an observational study of hospitalized bicyclists from a level 1 trauma centre
Acta Neurochir (Wien), 166 (1), 132
DOI 10.1007/s00701-024-06019-9, PubMed 38472419
Preservation of vision by transpalpebral electrical stimulation in mice with inherited retinal degeneration
Front Cell Dev Biol, 12, 1412909
DOI 10.3389/fcell.2024.1412909, PubMed 39206091
Effect of chlorhexidine, povidone-iodine and betadine antiseptic eye drops on cultured human conjunctival goblet cell survival
Acta Ophthalmol, 102 (7), 773-778
DOI 10.1111/aos.16684, PubMed 38553957
A Preservative-Free Approach - Effects on Dry Eye Signs and Symptoms After Cataract Surgery
Clin Ophthalmol, 18, 591-604
DOI 10.2147/OPTH.S446804, PubMed 38435373
Ectropion
Tidsskr Nor Laegeforen, 144 (1)
DOI 10.4045/tidsskr.23.0309, PubMed 38258716
Tear fluid reflects the altered protein expressions of Alzheimer's disease patients in proteins involved in protein repair and clearance system or the regulation of cytoskeleton
J Alzheimers Dis, 13872877241295315 (in press)
DOI 10.1177/13872877241295315, PubMed 39558606
Tear cytokine levels are reduced in patients treated with intravitreal injections
Ocul Surf, 32, 222-226
DOI 10.1016/j.jtos.2024.03.004, PubMed 38490478
Integrating Structured Digital Tools with the Traditional Hands-on Puzzle Method for Teaching Tooth Morphology: A Comparative Study of Educational Outcomes
Dent J (Basel), 12 (8)
DOI 10.3390/dj12080270, PubMed 39195114
Review of Hydroxypropyl Methylcellulose in Artificial Tears for the Treatment of Dry Eye Disease
Acta Ophthalmol, 102 (8), 881-896
DOI 10.1111/aos.16753, PubMed 39219040
Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients
Ocul Surf, 32, 123-129
DOI 10.1016/j.jtos.2024.02.002, PubMed 38354907
Whole genome sequencing and characterization of Corynebacterium isolated from the healthy and dry eye ocular surface
BMC Microbiol, 24 (1), 368
DOI 10.1186/s12866-024-03517-9, PubMed 39342108
Sex Differences in the Prevalence of Meibomian Gland Dysfunction: A Mini Review
Curr Eye Res, 49 (5), 447-457
DOI 10.1080/02713683.2023.2301325, PubMed 38196124
Identification of Transcripts with Shared Roles in the Pathogenesis of Postmenopausal Osteoporosis and Cardiovascular Disease
Int J Mol Sci, 25 (10)
DOI 10.3390/ijms25105554, PubMed 38791593
Investigation of Roles of SLC38A1 in Proliferation and Differentiation of Mouse Tongue Epithelium and Expression in Human Oral Tongue Squamous Cell Carcinoma
Cancers (Basel), 16 (2)
DOI 10.3390/cancers16020405, PubMed 38254895
Chalazion Treatment: A Concise Review of Clinical Trials
Curr Eye Res, 49 (2), 109-118
DOI 10.1080/02713683.2023.2279014, PubMed 37937798
Response predictors of a topical corticosteroid-based regimen for dry eyes: A real-life study
Acta Ophthalmol (in press)
DOI 10.1111/aos.16758, PubMed 39344883
Corrigendum to "Future directions in managing aniridia-associated keratopathy" [Surv Ophthalmol 68 (2023) 940-956]
Surv Ophthalmol, 69 (2), 300-301
DOI 10.1016/j.survophthal.2024.01.001, PubMed 38326136
Oxidative Stress, Persistent Inflammation and Blood Coagulation Alterations in Serum Proteome of Patients with Neovascular Age-Related Macular Degeneration
Life (Basel), 14 (5)
DOI 10.3390/life14050624, PubMed 38792644
Publications 2023
Electrical stimulation alters DNA methylation and promotes neurite outgrowth
J Cell Biochem, 124 (10), 1530-1545
DOI 10.1002/jcb.30462, PubMed 37642194
Comparison of Novel Wide-Field In Vivo Corneal Confocal Microscopy With Skin Biopsy for Assessing Peripheral Neuropathy in Type 2 Diabetes
Diabetes, 72 (7), 908-917
DOI 10.2337/db22-0863, PubMed 37058418
Ocular Surface Homeostasis After Scleral Lens Usage
Eye Contact Lens, 49 (11), 459-463
DOI 10.1097/ICL.0000000000001027, PubMed 37651199
Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics?
Int J Mol Sci, 24 (17)
DOI 10.3390/ijms241713409, PubMed 37686214
RNA Profiles of Tear Fluid Extracellular Vesicles in Patients with Dry Eye-Related Symptoms
Int J Mol Sci, 24 (20)
DOI 10.3390/ijms242015390, PubMed 37895069
Cross-sectional Study Exploring Vision-related Quality of Life in Dry Eye Disease in a Norwegian Optometric Practice
Optom Vis Sci, 100 (10), 679-687
DOI 10.1097/OPX.0000000000002058, PubMed 37751404
Intense pulsed light treatment in meibomian gland dysfunction: Past, present, and future
Acta Ophthalmol, 102 (4), e414-e442
DOI 10.1111/aos.15759, PubMed 37702308
Tear and Saliva Metabolomics in Evaporative Dry Eye Disease in Females
Metabolites, 13 (11)
DOI 10.3390/metabo13111125, PubMed 37999221
Purinergic 2X 4 (P2X4), but not P2X7, receptors increase cytosolic [Ca2+] and stimulate mucin secretion in rat conjunctival goblet cells to maintain ocular surface health
Exp Eye Res, 235, 109614
DOI 10.1016/j.exer.2023.109614, PubMed 37580003
Early ocular surface and tear film status in congenital aniridia indicates a supportive treatment window
Br J Ophthalmol, 108 (1), 30-36
DOI 10.1136/bjo-2021-320774, PubMed 36517210
Prevalence of Dry Eye Disease Among Individuals Scheduled for Cataract Surgery in a Norwegian Cataract Clinic
Clin Ophthalmol, 17, 1233-1243
DOI 10.2147/OPTH.S407805, PubMed 37138823
Comparing the effect of benzalkonium chloride-preserved, polyquad-preserved, and preservative-free prostaglandin analogue eye drops on cultured human conjunctival goblet cells
J Optom, 17 (1), 100481
DOI 10.1016/j.optom.2023.100481, PubMed 37788596
Ex Vivo Pig Eye Model for Studying Diffusion of Acylcarnitines with Different Physicochemical Properties
J Ocul Pharmacol Ther, 39 (5), 324-331
DOI 10.1089/jop.2022.0159, PubMed 37219540
A comparison between hyaluronic acid and other single ingredient eye drops for dry eye, a review
Acta Ophthalmol, 102 (1), 25-37
DOI 10.1111/aos.15675, PubMed 37042308
Suture materials
Tidsskr Nor Laegeforen, 143 (10)
DOI 10.4045/tidsskr.22.0708, PubMed 37376937
[Not Available]
Tidsskr Nor Laegeforen, 143
DOI 10.4045/tidsskr.23.0446, PubMed 37376981
Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment
Ocul Surf, 29, 456-468
DOI 10.1016/j.jtos.2023.05.012, PubMed 37302545
Anti-Inflammatory and Pro-Resolving Actions of the N-Terminal Peptides Ac2-26, Ac2-12, and Ac9-25 of Annexin A1 on Conjunctival Goblet Cell Function
Am J Pathol, 193 (11), 1817-1832
DOI 10.1016/j.ajpath.2023.05.020, PubMed 37423551
Greater adherence to a mediterranean diet is associated with lower C-reactive protein (CRP) levels, but not to lower odds of having dry eye disease
Ocul Surf, 30, 196-203
DOI 10.1016/j.jtos.2023.09.013, PubMed 37783428
Risk associated with treatments for meibomian gland dysfunction
Cont Lens Anterior Eye, 46 (2), 101818
DOI 10.1016/j.clae.2023.101818, PubMed 36754735
Associations between Serial Intravitreal Injections and Dry Eye
Ophthalmology, 130 (5), 509-515
DOI 10.1016/j.ophtha.2023.01.009, PubMed 36693594
The work-related burden of dry eye
Ocul Surf, 28, 30-36
DOI 10.1016/j.jtos.2023.01.006, PubMed 36690155
Meibomian Gland Dysfunction Is Associated with Low Levels of Immunoglobulin Chains and Cystatin-SN
Int J Mol Sci, 24 (20)
DOI 10.3390/ijms242015115, PubMed 37894795
Anterior blepharitis is associated with elevated plectin levels consistent with a pronounced intracellular response
Ocul Surf, 29, 444-455
DOI 10.1016/j.jtos.2023.06.010, PubMed 37348651
Tear film proteome changes following Tobradex® therapy in anterior blepharitis
Acta Ophthalmol, 102 (4), e565-e576
DOI 10.1111/aos.15792, PubMed 37837306
Allogeneic mesenchymal stem cell therapy for dry eye disease in patients with Sjögren's syndrome: A randomized clinical trial
Ocul Surf, 31, 1-8
DOI 10.1016/j.jtos.2023.11.007, PubMed 38049032
Surgical Procedures in the Treatment of Dry Eye Disease
J Ocul Pharmacol Ther, 39 (10), 692-698
DOI 10.1089/jop.2023.0063, PubMed 37566528
The relationship between sedentary behavior and dry eye disease
Ocul Surf, 28, 11-17
DOI 10.1016/j.jtos.2023.01.002, PubMed 36621639
Rod and Cone Dark Adaptation in Congenital Aniridia and Its Association With Retinal Structure
Invest Ophthalmol Vis Sci, 64 (4), 18
DOI 10.1167/iovs.64.4.18, PubMed 37067366
Using machine learning model explanations to identify proteins related to severity of meibomian gland dysfunction
Sci Rep, 13 (1), 22946
DOI 10.1038/s41598-023-50342-7, PubMed 38135766
Future directions in managing aniridia-associated keratopathy
Surv Ophthalmol, 68 (5), 940-956
DOI 10.1016/j.survophthal.2023.04.003, PubMed 37146692
TFOS Lifestyle: Impact of the digital environment on the ocular surface
Ocul Surf, 28, 213-252
DOI 10.1016/j.jtos.2023.04.004, PubMed 37062428
Publications 2022
Substantial increase in the incidence of rhegmatogenous retinal detachment in Western Norway over 20 years
Acta Ophthalmol, 100 (7), 763-768
DOI 10.1111/aos.15119, PubMed 35261167
Epigenetic Regulation of Optic Nerve Development, Protection, and Repair
Int J Mol Sci, 23 (16)
DOI 10.3390/ijms23168927, PubMed 36012190
The use of in vivo confocal microscopy in fungal keratitis - Progress and challenges
Ocul Surf, 24, 103-118
DOI 10.1016/j.jtos.2022.03.002, PubMed 35278721
In-office thermal systems for the treatment of dry eye disease
Surv Ophthalmol, 67 (5), 1405-1418
DOI 10.1016/j.survophthal.2022.02.007, PubMed 35192836
The Therapeutic Benefits of Nanoencapsulation in Drug Delivery to the Anterior Segment of the Eye: A Systematic Review
Front Pharmacol, 13, 903519
DOI 10.3389/fphar.2022.903519, PubMed 35645827
Resolvin D2 uses multiple Ca2+ -dependent signaling pathways to stimulate mucin secretion in rat and human conjunctival goblet cells
J Cell Physiol, 237 (10), 3816-3833
DOI 10.1002/jcp.30854, PubMed 36066128
Morphology of Meibomian Glands in a 65-Year-Old Norwegian Population without Dry Eye Disease
J Clin Med, 11 (3)
DOI 10.3390/jcm11030527, PubMed 35159978
Anatomical distribution of mandibular fractures from severe bicycling accidents: A 12-year experience from a Norwegian level 1 trauma center
Dent Traumatol, 38 (5), 424-430
DOI 10.1111/edt.12756, PubMed 35481880
Seasonal variations in presenting symptoms and signs of dry eye disease in Norway
Sci Rep, 12 (1), 21046
DOI 10.1038/s41598-022-25557-9, PubMed 36473933
Effect of femtosecond laser cutting parameters on the results of small-incision lenticule extraction
J Cataract Refract Surg, 48 (11), 1253-1259
DOI 10.1097/j.jcrs.0000000000000965, PubMed 35537865
Heidelberg Anterion Swept-Source OCT Corneal Epithelial Thickness Mapping: Repeatability and Agreement With Optovue Avanti
J Refract Surg, 38 (6), 356-363
DOI 10.3928/1081597X-20220414-01, PubMed 35686707
Topical glaucoma medications - Clinical implications for the ocular surface
Ocul Surf, 26, 19-49
DOI 10.1016/j.jtos.2022.07.007, PubMed 35921942
Predicting an unstable tear film through artificial intelligence
Sci Rep, 12 (1), 21416
DOI 10.1038/s41598-022-25821-y, PubMed 36496510
Review on the possible pathophysiological mechanisms underlying visual display terminal-associated dry eye disease
Acta Ophthalmol, 100 (8), 861-877
DOI 10.1111/aos.15150, PubMed 35441459
Facial Fractures and Their Relation to Head and Cervical Spine Injuries in Hospitalized Bicyclists
J Craniofac Surg, 34 (1), 34-39
DOI 10.1097/SCS.0000000000009032, PubMed 36608095
Heavy-load exercise in older adults activates vasculogenesis and has a stronger impact on muscle gene expression than in young adults
Eur Rev Aging Phys Act, 19 (1), 23
DOI 10.1186/s11556-022-00304-1, PubMed 36182918
In silico discovery of blood cell macromolecular associations
BMC Genom Data, 23 (1), 57
DOI 10.1186/s12863-022-01077-3, PubMed 35879676
Transcriptomic and functional studies reveal miR-431-5p as a tumour suppressor in pancreatic ductal adenocarcinoma cells
Gene, 822, 146346
DOI 10.1016/j.gene.2022.146346, PubMed 35182679
Proteomic Profiling of Saliva and Tears in Radiated Head and Neck Cancer Patients as Compared to Primary Sjögren's Syndrome Patients
Int J Mol Sci, 23 (7)
DOI 10.3390/ijms23073714, PubMed 35409074
Saliva Metabolomics in Dry Mouth Patients with Head and Neck Cancer or Sjögren's Syndrome
Cells, 11 (3)
DOI 10.3390/cells11030323, PubMed 35159133
The relationship between ocular and oral dryness in a cohort from the 65-year-old population in Norway
Sci Rep, 12 (1), 9805
DOI 10.1038/s41598-022-13985-6, PubMed 35697848
Hyaluronic acid in the treatment of dry eye disease
Acta Ophthalmol, 100 (8), 844-860
DOI 10.1111/aos.15159, PubMed 35514082
Dry eye disease and proteomics
Ocul Surf, 24, 119-128
DOI 10.1016/j.jtos.2022.03.001, PubMed 35278720
Role of stem cells in regenerative treatment of dry eye disease caused by lacrimal gland dysfunction
Acta Ophthalmol, 101 (4), 360-375
DOI 10.1111/aos.15629, PubMed 36564971
Time and Temperature Stability of TGF-β1, EGF and IGF-1 in 20% and 100% Human Serum
Folia Biol (Praha), 68 (2), 45-49
PubMed 36384261
Video display terminal use and dry eye: preventive measures and future perspectives
Acta Ophthalmol, 100 (7), 723-739
DOI 10.1111/aos.15105, PubMed 35122403
Skin grafting
Tidsskr Nor Laegeforen, 142 (8)
DOI 10.4045/tidsskr.21.0671, PubMed 35635412
Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels
J Ophthalmol, 2022, 5103231
DOI 10.1155/2022/5103231, PubMed 35967518
Direct modulation of microglial function by electrical field
Front Cell Dev Biol, 10, 980775
DOI 10.3389/fcell.2022.980775, PubMed 36158207
Neuronal Intranuclear Inclusion Disease-Related Neurotrophic Keratitis: A Case Report
Brain Sci, 12 (6)
DOI 10.3390/brainsci12060782, PubMed 35741666
The Relationship Between Caffeine Intake and Dry Eye Disease
Cornea, 42 (2), 186-193
DOI 10.1097/ICO.0000000000002979, PubMed 35081066
The relationship between habitual water intake and dry eye disease
Acta Ophthalmol, 101 (1), 65-73
DOI 10.1111/aos.15227, PubMed 35941821
Signaling Pathways Used by the Specialized Pro-Resolving Mediator Maresin 2 Regulate Goblet Cell Function: Comparison with Maresin 1
Int J Mol Sci, 23 (11)
DOI 10.3390/ijms23116233, PubMed 35682912
Autofluorescence Imaging in the Long-Term Follow-Up of Scleral Buckling Surgery for Retinal Detachment
J Ophthalmol, 2022, 2119439
DOI 10.1155/2022/2119439, PubMed 35265365
Hot towels: The bedrock of Meibomian gland dysfunction treatment - A review
Cont Lens Anterior Eye, 46 (2), 101775
DOI 10.1016/j.clae.2022.101775, PubMed 36715292
Adverse Effects and Safety in Glaucoma Patients: Agreement on Clinical Trial Outcomes for Reports on Eye Drops (ASGARD)-A Delphi Consensus Statement
Am J Ophthalmol, 241, 190-197
DOI 10.1016/j.ajo.2022.05.007, PubMed 35594917
Antibiotic treatment for dry eye disease related to meibomian gland dysfunction and blepharitis - A review
Ocul Surf, 26, 211-221
DOI 10.1016/j.jtos.2022.08.010, PubMed 36210626
Sex-based differences in conjunctival goblet cell responses to pro-inflammatory and pro-resolving mediators
Sci Rep, 12 (1), 16305
DOI 10.1038/s41598-022-20177-9, PubMed 36175572
Transcorneal but not transpalpebral electrical stimulation disrupts mucin homeostasis of the ocular surface
BMC Ophthalmol, 22 (1), 490
DOI 10.1186/s12886-022-02717-z, PubMed 36522696
Retinal Pigment Epithelium Transplantation: Past, Present, and Future
J Ophthalmic Vis Res, 17 (4), 574-580
DOI 10.18502/jovr.v17i4.12325, PubMed 36620704
Publications 2021
Parkinson's disease with restless legs syndrome-an in vivo corneal confocal microscopy study
NPJ Parkinsons Dis, 7 (1), 4
DOI 10.1038/s41531-020-00148-5, PubMed 33402694
Wide-field mosaics of the corneal subbasal nerve plexus in Parkinson's disease using in vivo confocal microscopy
Sci Data, 8 (1), 306
DOI 10.1038/s41597-021-01087-3, PubMed 34836991
The pattern of the inferocentral whorl region of the corneal subbasal nerve plexus is altered with age
Ocul Surf, 22, 204-212
DOI 10.1016/j.jtos.2021.08.015, PubMed 34450219
Meibomian gland dysfunction is highly prevalent among first-time visitors at a Norwegian dry eye specialist clinic
Sci Rep, 11 (1), 23412
DOI 10.1038/s41598-021-02738-6, PubMed 34862425
Non-invasive electrical stimulation as a potential treatment for retinal degenerative diseases
Neural Regen Res, 16 (8), 1558-1559
DOI 10.4103/1673-5374.303015, PubMed 33433481
Alterations in meibomian glands in patients treated with intensity-modulated radiotherapy for head and neck cancer
Sci Rep, 11 (1), 22419
DOI 10.1038/s41598-021-01844-9, PubMed 34789830
Cost Analysis of Open Surgical Bedside Tracheostomy in Intensive Care Unit Patients
Ear Nose Throat J, 102 (8), 516-521
DOI 10.1177/01455613211018578, PubMed 34006128
Characterization of Lipids in Saliva, Tears and Minor Salivary Glands of Sjögren's Syndrome Patients Using an HPLC/MS-Based Approach
Int J Mol Sci, 22 (16)
DOI 10.3390/ijms22168997, PubMed 34445702
The association between visual display terminal use and dry eye: a review
Acta Ophthalmol, 100 (4), 357-375
DOI 10.1111/aos.15049, PubMed 34697901
Perturbation of astroglial Slc38 glutamine transporters by NH4+ contributes to neurophysiologic manifestations in acute liver failure
FASEB J, 35 (7), e21588
DOI 10.1096/fj.202001712RR, PubMed 34169573
NF-κB activation in retinal microglia is involved in the inflammatory and neovascularization signaling in laser-induced choroidal neovascularization in mice
Exp Cell Res, 403 (1), 112581
DOI 10.1016/j.yexcr.2021.112581, PubMed 33811906
Concise Review: Considering Optimal Temperature for Short-Term Storage of Epithelial Cells
Front Med (Lausanne), 8, 686774
DOI 10.3389/fmed.2021.686774, PubMed 34485330
Corrigendum: Concise Review: Considering Optimal Temperature for Short-Term Storage of Epithelial Cells
Front Med (Lausanne), 8, 775351
DOI 10.3389/fmed.2021.775351, PubMed 34676230
The Silk Protein Sericin Promotes Viability of ARPE-19 and Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells in vitro
Curr. Eye Res., 46 (4), 504-514
DOI 10.1080/02713683.2020.1809001
Congenital aniridia - A comprehensive review of clinical features and therapeutic approaches
Surv Ophthalmol, 66 (6), 1031-1050
DOI 10.1016/j.survophthal.2021.02.011, PubMed 33675823
Authors' response to letter to the editor: Congenital aniridia - a comprehensive review of clinical features and therapeutic approach
Surv Ophthalmol, 67 (2), 629-630
DOI 10.1016/j.survophthal.2021.11.001, PubMed 34748793
Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca2+ and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases
Front Immunol, 12, 618653
DOI 10.3389/fimmu.2021.618653, PubMed 33968020
Intraductal meibomian gland probing and its efficacy in the treatment of meibomian gland dysfunction
Surv Ophthalmol, 66 (4), 612-622
DOI 10.1016/j.survophthal.2020.11.005, PubMed 33352147
The relationship between alcohol consumption and dry eye
Ocul Surf, 21, 87-95
DOI 10.1016/j.jtos.2021.05.005, PubMed 34029755
Chambered warm moist air eyelid warming devices - a review
Acta Ophthalmol, 100 (5), 499-510
DOI 10.1111/aos.15052, PubMed 34750979
The relationship between dry eye and sleep quality
Ocul Surf, 20, 13-19
DOI 10.1016/j.jtos.2020.12.009, PubMed 33421635
The physical and mental burden of dry eye disease: A large population-based study investigating the relationship with health-related quality of life and its determinants
Ocul Surf, 21, 107-117
DOI 10.1016/j.jtos.2021.05.006, PubMed 34044135
The vision-related burden of dry eye
Ocul Surf, 23, 207-215
DOI 10.1016/j.jtos.2021.10.007, PubMed 34743866
Impact of benzalkonium chloride-preserved and preservative-free latanoprost eye drops on cultured human conjunctival goblet cells upon acute exposure and differences in physicochemical properties of the eye drops
BMJ Open Ophthalmol, 6 (1), e000892
DOI 10.1136/bmjophth-2021-000892, PubMed 34993350
TheraPearl Eye Mask and Blephasteam for the treatment of meibomian gland dysfunction: a randomized, comparative clinical trial
Sci Rep, 11 (1), 22386
DOI 10.1038/s41598-021-01899-8, PubMed 34789807
Ex vivo expansion and characterization of human corneal endothelium for transplantation: a review
Stem Cell Res Ther, 12 (1), 554
DOI 10.1186/s13287-021-02611-3, PubMed 34717745
Artificial intelligence in dry eye disease
Ocul Surf, 23, 74-86
DOI 10.1016/j.jtos.2021.11.004, PubMed 34843999
STRUCTURAL PATHOLOGY AFTER RETINAL DETACHMENT: Multicolor Confocal Scanning Laser Ophthalmoscopy Versus Color Fundus Photography
Retina, 41 (9), 1958-1965
DOI 10.1097/IAE.0000000000003113, PubMed 33464027
Therapeutic Strategies for Dry Mouth Management with Emphasis on Electrostimulation as a Treatment Option
Int J Dent, 2021, 6043488
DOI 10.1155/2021/6043488, PubMed 34691182
Genetic Aspects of Dental Erosive Wear and Dental Caries
Int J Dent, 2021, 5566733
DOI 10.1155/2021/5566733, PubMed 34335772
Oral and ocular late effects in head and neck cancer patients treated with radiotherapy
Sci Rep, 11 (1), 4026
DOI 10.1038/s41598-021-83635-w, PubMed 33597629
Medication use and dry eye symptoms: A large, hypothesis-free, population-based study in the Netherlands
Ocul Surf, 22, 1-12
DOI 10.1016/j.jtos.2021.06.009, PubMed 34171471
Resolvin D2 and Resolvin D1 Differentially Activate Protein Kinases to Counter-Regulate Histamine-Induced [Ca2+]i Increase and Mucin Secretion in Conjunctival Goblet Cells
Int J Mol Sci, 23 (1)
DOI 10.3390/ijms23010141, PubMed 35008563
Eye Make-up Products and Dry Eye Disease: A Mini Review
Curr Eye Res, 47 (1), 1-11
DOI 10.1080/02713683.2021.1966476, PubMed 34365876
Tear Film Break-Up Time and Dry Eye Disease Severity in a Large Norwegian Cohort
J Clin Med, 10 (4)
DOI 10.3390/jcm10040884, PubMed 33671667
Intraoperative Swept-Source OCT-Based Corneal Topography for Measurement and Analysis of Stromal Surface After Epithelial Removal
J Refract Surg, 37 (7), 484-492
DOI 10.3928/1081597X-20210405-01, PubMed 34236903
Publications 2020
Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways
Cells, 9 (9)
DOI 10.3390/cells9092050, PubMed 32911805
Region of interest and directional analysis of subbasal nerves in wide-area corneal nerve plexus mosaics in type 2 diabetes mellitus
Sci Rep, 10 (1), 10802
DOI 10.1038/s41598-020-67737-5, PubMed 32612112
Dry eye disease treatment: the role of tear substitutes, their future, and an updated classification
Eur Rev Med Pharmacol Sci, 24 (17), 8642-8652
DOI 10.26355/eurrev_202009_22801, PubMed 32964952
Ex vivo cultivated oral mucosal epithelial cell transplantation for limbal stem cell deficiency: a review
Stem Cell Res Ther, 11 (1), 301
DOI 10.1186/s13287-020-01783-8, PubMed 32693830
Dentoalveolar injuries, bicycling accidents and helmet use in patients referred to a Norwegian Trauma Centre: A 12-year prospective study
Dent Traumatol, 37 (2), 240-246
DOI 10.1111/edt.12627, PubMed 33220164
Electrical Stimulation Induces Retinal Müller Cell Proliferation and Their Progenitor Cell Potential
Cells, 9 (3)
DOI 10.3390/cells9030781, PubMed 32210151
TFOS European Ambassador meeting: Unmet needs and future scientific and clinical solutions for ocular surface diseases
Ocul Surf, 18 (4), 936-962
DOI 10.1016/j.jtos.2020.05.006, PubMed 32504856
The role of meibography in ocular surface diagnostics: A review
Ocul Surf, 19, 133-144
DOI 10.1016/j.jtos.2020.05.004, PubMed 32416235
Lacrimal Gland Myoepithelial Cells Are Altered in a Mouse Model of Dry Eye Disease
Am J Pathol, 190 (10), 2067-2079
DOI 10.1016/j.ajpath.2020.06.013, PubMed 32679229
Distinct Subsets of Noncoding RNAs Are Strongly Associated With BMD and Fracture, Studied in Weight-Bearing and Non-Weight-Bearing Human Bone
J Bone Miner Res, 35 (6), 1065-1076
DOI 10.1002/jbmr.3974, PubMed 32017184
The Effects of Prolonged Storage on ARPE-19 Cells Stored at Three Different Storage Temperatures
Molecules, 25 (24)
DOI 10.3390/molecules25245809, PubMed 33317020
Optisol-GS Storage of Cultured Human Limbal Epithelial Cells at Ambient Temperature Is Superior to Hypothermic Storage
Curr Eye Res, 45 (12), 1497-1503
DOI 10.1080/02713683.2020.1770295, PubMed 32578462
Aberrant HLA-DR expression in the conjunctival epithelium after autologous serum treatment in patients with graft-versus-host disease or Sjögren's syndrome
PLoS One, 15 (4), e0231473
DOI 10.1371/journal.pone.0231473, PubMed 32315325
Scanning Electron Microscopy Observations of Loa loa (Nematoda)
Case Rep Ophthalmol, 11 (2), 486-492
DOI 10.1159/000509338, PubMed 32999680
Sericin-Induced Melanogenesis in Cultured Retinal Pigment Epithelial Cells Is Associated with Elevated Levels of Hydrogen Peroxide and Inflammatory Proteins
Molecules, 25 (19)
DOI 10.3390/molecules25194395, PubMed 32987810
The Silk Protein Sericin Promotes Viability of ARPE-19 and Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells in vitro
Curr Eye Res, 46 (4), 504-514
DOI 10.1080/02713683.2020.1809001, PubMed 32777180
Twenty years of endophthalmitis: Incidence, aetiology and clinical outcome
Acta Ophthalmol, 99 (1), e62-e69
DOI 10.1111/aos.14511, PubMed 32567150
Maresin 1, a specialized proresolving mediator, stimulates intracellular [Ca2+ ] and secretion in conjunctival goblet cells
J Cell Physiol, 236 (1), 340-353
DOI 10.1002/jcp.29846, PubMed 32510663
Temporal redistribution of cap and residual stromal thickness after SMILE
J Cataract Refract Surg, 46 (10), 1331-1338
DOI 10.1097/j.jcrs.0000000000000242, PubMed 32398471
Postmenopausal osteoporosis is a musculoskeletal disease with a common genetic trait which responds to strength training: a translational intervention study
Ther Adv Musculoskelet Dis, 12, 1759720X20929443
DOI 10.1177/1759720X20929443, PubMed 32536985
PAX6 Genotypic and Retinal Phenotypic Characterization in Congenital Aniridia
Invest Ophthalmol Vis Sci, 61 (5), 14
DOI 10.1167/iovs.61.5.14, PubMed 32396632
Slc38a1 Conveys Astroglia-Derived Glutamine into GABAergic Interneurons for Neurotransmitter GABA Synthesis
Cells, 9 (7)
DOI 10.3390/cells9071686, PubMed 32668809
Stem cell function is conserved during short-term storage of cultured epidermal cell sheets at 12°C
PLoS One, 15 (5), e0232270
DOI 10.1371/journal.pone.0232270, PubMed 32433698
Povidone iodine treatment is deleterious to human ocular surface conjunctival cells in culture
BMJ Open Ophthalmol, 5 (1), e000545
DOI 10.1136/bmjophth-2020-000545, PubMed 32995498
Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study
Sci Rep, 10 (1), 2063
DOI 10.1038/s41598-020-59078-0, PubMed 32034249
Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease
Sci Rep, 10 (1), 5542
DOI 10.1038/s41598-020-62583-x, PubMed 32218518
Intense pulsed light treatment in meibomian gland dysfunction: A concise review
Ocul Surf, 18 (4), 583-594
DOI 10.1016/j.jtos.2020.06.002, PubMed 32629039
Sex and age differences in symptoms and signs of dry eye disease in a Norwegian cohort of patients
Ocul Surf, 19, 68-73
DOI 10.1016/j.jtos.2020.11.009, PubMed 33246035
Dental erosion in mice with impaired salivary gland function
Acta Odontol Scand, 78 (5), 390-400
DOI 10.1080/00016357.2020.1734234, PubMed 32141357
Microdot Accumulation in the Anterior Cornea with Aging - Quantitative Analysis with in Vivo Confocal Microscopy
Curr Eye Res, 45 (9), 1058-1064
DOI 10.1080/02713683.2020.1725062, PubMed 32026738
Advances, limitations and future perspectives in the diagnosis and management of dry eye in Sjögren's syndrome
Clin Exp Rheumatol, 38 Suppl 126 (4), 301-309
PubMed 33025899
Advances, limitations and future perspectives in the diagnosis and management of dry eye in Sjogren's syndrome
Clin. Exp. Rheumatol., 38 (4 126), S301-S309
RvE1 uses the LTB4 receptor BLT1 to increase [Ca2+]i and stimulate mucin secretion in cultured rat and human conjunctival goblet cells
Ocul Surf, 18 (3), 470-482
DOI 10.1016/j.jtos.2020.04.011, PubMed 32361084
Response of human oral mucosal epithelial cells to different storage temperatures: A structural and transcriptional study
PLoS One, 15 (12), e0243914
DOI 10.1371/journal.pone.0243914, PubMed 33326470
Noninvasive Electrical Stimulation Improves Photoreceptor Survival and Retinal Function in Mice with Inherited Photoreceptor Degeneration
Invest Ophthalmol Vis Sci, 61 (4), 5
DOI 10.1167/iovs.61.4.5, PubMed 32271885
Publications 2019
Proteomic and histopathological characterisation of sicca subjects and primary Sjögren's syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
Arthritis Res Ther, 21 (1), 181
DOI 10.1186/s13075-019-1961-4, PubMed 31366407
Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells
FASEB J, 33 (7), 8468-8478
DOI 10.1096/fj.201802467R, PubMed 31013438
Elevated cytokine levels in tears and saliva of patients with primary Sjögren's syndrome correlate with clinical ocular and oral manifestations
Sci Rep, 9 (1), 7319
DOI 10.1038/s41598-019-43714-5, PubMed 31086200
Simple limbal epithelial transplantation: Current status and future perspectives
Stem Cells Transl Med, 9 (3), 316-327
DOI 10.1002/sctm.19-0203, PubMed 31802651
PAX6 Mutational Status Determines Aniridia-Associated Keratopathy Phenotype
Ophthalmology, 127 (2), 273-275
DOI 10.1016/j.ophtha.2019.09.034, PubMed 31708273
Early phenotypic features of aniridia-associated keratopathy and association with PAX6 coding mutations
Ocul Surf, 18 (1), 130-140
DOI 10.1016/j.jtos.2019.11.002, PubMed 31734509
Characteristics and Utility of Fundus Autofluorescence in Congenital Aniridia Using Scanning Laser Ophthalmoscopy
Invest Ophthalmol Vis Sci, 60 (13), 4120-4128
DOI 10.1167/iovs.19-26994, PubMed 31574536
The Cone Photoreceptor Mosaic in Aniridia: Within-Family Phenotype-Genotype Discordance
Ophthalmol Retina, 3 (6), 523-534
DOI 10.1016/j.oret.2019.01.020, PubMed 31174676
The Glutamine Transporter Slc38a1 Regulates GABAergic Neurotransmission and Synaptic Plasticity
Cereb Cortex, 29 (12), 5166-5179
DOI 10.1093/cercor/bhz055, PubMed 31050701
Dry eyes - diagnostics and treatment
Tidsskr. Nor. Laegeforen., 139 (11), 1061-1064
[Dry eye disease – diagnosis and treatment]
Tidsskr Nor Laegeforen, 139 (11)
DOI 10.4045/tidsskr.18.0752, PubMed 31429248
Quality of life, patient satisfaction and cosmetic outcome after delayed breast reconstruction using DIEP flap: a 10 years' follow-up survey
J Plast Surg Hand Surg, 53 (2), 119-124
DOI 10.1080/2000656X.2018.1562459, PubMed 30654667
Interleukin-13 maintains the stemness of conjunctival epithelial cell cultures prepared from human limbal explants
PLoS One, 14 (2), e0211861
DOI 10.1371/journal.pone.0211861, PubMed 30742646
Conjunctival Goblet Cells, the Overlooked Cells in Glaucoma Treatment
J Glaucoma, 28 (4), 325-333
DOI 10.1097/IJG.0000000000001168, PubMed 30585937
Effects of explant size on epithelial outgrowth, thickness, stratification, ultrastructure and phenotype of cultured limbal epithelial cells
PLoS One, 14 (3), e0212524
DOI 10.1371/journal.pone.0212524, PubMed 30861002
Visual Contrast Sensitivity Correlates to the Retinal Degeneration in Rhodopsin Knockout Mice
Invest Ophthalmol Vis Sci, 60 (13), 4196-4204
DOI 10.1167/iovs.19-26966, PubMed 31618423
Functional and Morphological Evaluation of Meibomian Glands in the Assessment of Meibomian Gland Dysfunction Subtype and Severity
Am J Ophthalmol, 209, 160-167
DOI 10.1016/j.ajo.2019.09.005, PubMed 31526799
Diagnostic Test Efficacy of Meibomian Gland Morphology and Function
Sci Rep, 9 (1), 17345
DOI 10.1038/s41598-019-54013-4, PubMed 31758085
Evaluation of the Ocular Surface Disease Index Questionnaire as a Discriminative Test for Clinical Findings in Dry Eye Disease Patients
Curr Eye Res, 44 (9), 941-947
DOI 10.1080/02713683.2019.1604972, PubMed 30955380
Tear Metabolomics in Dry Eye Disease: A Review
Int J Mol Sci, 20 (15)
DOI 10.3390/ijms20153755, PubMed 31374809
Hyaluronan-Based Hydrogel Scaffolds for Limbal Stem Cell Transplantation: A Review
Cells, 8 (3)
DOI 10.3390/cells8030245, PubMed 30875861
A Hyaluronan Hydrogel Scaffold for Culture of Human Oral Mucosal Epithelial Cells in Limbal Stem-Cell Therapy
Bioengineering (Basel), 6 (4)
DOI 10.3390/bioengineering6040097, PubMed 31652804
Transepithelial Topography-Guided Ablation Assisted by Epithelial Thickness Mapping for Treatment of Regression After Myopic Refractive Surgery
J Refract Surg, 35 (8), 525-533
DOI 10.3928/1081597X-20190730-01, PubMed 31393991
Publications 2018
Meibomian Gland Morphology Is a Sensitive Early Indicator of Meibomian Gland Dysfunction
Am J Ophthalmol, 200, 16-25
DOI 10.1016/j.ajo.2018.12.006, PubMed 30578784
Severity of clinical dry eye manifestations influences protein expression in tear fluid of patients with primary Sjögren's syndrome
PLoS One, 13 (10), e0205762
DOI 10.1371/journal.pone.0205762, PubMed 30312344
Characterization and comparison of human limbal explant cultures grown under defined and xeno-free conditions
Exp Eye Res, 176, 20-28
DOI 10.1016/j.exer.2018.06.019, PubMed 29928900
IGFBPL1 Regulates Axon Growth through IGF-1-mediated Signaling Cascades
Sci Rep, 8 (1), 2054
DOI 10.1038/s41598-018-20463-5, PubMed 29391597
Activation of the EGF Receptor by Histamine Receptor Subtypes Stimulates Mucin Secretion in Conjunctival Goblet Cells
Invest Ophthalmol Vis Sci, 59 (8), 3543-3553
DOI 10.1167/iovs.18-2476, PubMed 30025103
Resolvin D1, but not resolvin E1, transactivates the epidermal growth factor receptor to increase intracellular calcium and glycoconjugate secretion in rat and human conjunctival goblet cells
Exp Eye Res, 180, 53-62
DOI 10.1016/j.exer.2018.11.018, PubMed 30513286
Cultured Human Retinal Pigment Epithelial (hRPE) Sheets: A Search for Suitable Storage Conditions
Microsc Microanal, 24 (2), 147-155
DOI 10.1017/S1431927618000144, PubMed 29637873
Wide-field corneal subbasal nerve plexus mosaics in age-controlled healthy and type 2 diabetes populations
Sci Data, 5, 180075
DOI 10.1038/sdata.2018.75, PubMed 29688226
Dendritic cell maturation in the corneal epithelium with onset of type 2 diabetes is associated with tumor necrosis factor receptor superfamily member 9
Sci Rep, 8 (1), 14248
DOI 10.1038/s41598-018-32410-5, PubMed 30250206
Meibomian gland dysfunction and keratopathy are associated with dry eye disease in aniridia
Br J Ophthalmol, 103 (1), 119-124
DOI 10.1136/bjophthalmol-2017-310927, PubMed 29519880
The Level of Inflammatory Tear Cytokines is Elevated in Congenital Aniridia and Associated with Meibomian Gland Dysfunction
Invest Ophthalmol Vis Sci, 59 (5), 2197-2204
DOI 10.1167/iovs.18-24027, PubMed 29801153
Signaling pathways activated by resolvin E1 to stimulate mucin secretion and increase intracellular Ca2+ in cultured rat conjunctival goblet cells
Exp Eye Res, 173, 64-72
DOI 10.1016/j.exer.2018.04.015, PubMed 29702100
Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
Nat Commun, 9 (1), 3665
DOI 10.1038/s41467-018-05578-7, PubMed 30202009
Transcriptomic analysis of MicroRNA expression in enamel-producing cells
Gene, 688, 193-203
DOI 10.1016/j.gene.2018.11.089, PubMed 30529249
Improvement of Storage Medium for Cultured Human Retinal Pigment Epithelial Cells Using Factorial Design
Sci Rep, 8 (1), 5688
DOI 10.1038/s41598-018-24121-8, PubMed 29632395
Color Vision in Aniridia
Invest Ophthalmol Vis Sci, 59 (5), 2142-2152
DOI 10.1167/iovs.17-23047, PubMed 29801149
High Throughput Screening of Additives Using Factorial Design to Promote Survival of Stored Cultured Epithelial Sheets
Stem Cells Int, 2018, 6545876
DOI 10.1155/2018/6545876, PubMed 30581473
ULTRA-WIDE-FIELD FUNDUS IMAGING IN THE DIAGNOSIS AND FOLLOW-UP OF SUSAC SYNDROME
Retin Cases Brief Rep, 12 (3), 234-239
DOI 10.1097/ICB.0000000000000470, PubMed 27828899
Exposure to antazoline-naphazoline eye drops during pregnancy and the risk of congenital malformations: a Danish nationwide cohort study
Acta Ophthalmol, 97 (5), 505-509
DOI 10.1111/aos.13980, PubMed 30479070
New animal model of extrinsic dental erosion-Erosive effect on the mouse molar teeth
Arch Oral Biol, 96, 137-145
DOI 10.1016/j.archoralbio.2018.08.013, PubMed 30241000
Effect of Transportation on Cultured Limbal Epithelial Sheets for Worldwide Treatment of Limbal Stem Cell Deficiency
Sci Rep, 8 (1), 10502
DOI 10.1038/s41598-018-28553-0, PubMed 30002380
Concise Review: Altered Versus Unaltered Amniotic Membrane as a Substrate for Limbal Epithelial Cells
Stem Cells Transl Med, 7 (5), 415-427
DOI 10.1002/sctm.17-0257, PubMed 29573222
Tear Production Levels and Dry Eye Disease Severity in a Large Norwegian Cohort
Curr Eye Res, 43 (12), 1465-1470
DOI 10.1080/02713683.2018.1514055, PubMed 30183390
Transcription and microRNA Profiling of Cultured Human Tympanic Membrane Epidermal Keratinocytes
J Assoc Res Otolaryngol, 19 (3), 243-260
DOI 10.1007/s10162-018-0660-1, PubMed 29623476
Publications 2017
Identification of potential saliva and tear biomarkers in primary Sjögren's syndrome, utilising the extraction of extracellular vesicles and proteomics analysis
Arthritis Res Ther, 19 (1), 14
DOI 10.1186/s13075-017-1228-x, PubMed 28122643
Medium- to Long-Term Results of Corneal Cross-Linking for Keratoconus Using Phototherapeutic Keratectomy for Epithelial Removal and Partial Stromal Ablation
J Refract Surg, 33 (7), 488-495
DOI 10.3928/1081597X-20170504-03, PubMed 28681909
Meibomian gland features in a Norwegian cohort of patients with primary Sjögren´s syndrome
PLoS One, 12 (9), e0184284
DOI 10.1371/journal.pone.0184284, PubMed 28886085
Identification of Objective Morphometric Markers of Xerostomia in the Oral Mucosa Epithelium with In Vivo Confocal Microscopy
Microsc Microanal, 23 (1), 88-96
DOI 10.1017/S1431927617000022, PubMed 28162126
Tissue Harvesting Site and Culture Medium Affect Attachment, Growth, and Phenotype of Ex Vivo Expanded Oral Mucosal Epithelial Cells
Sci Rep, 7 (1), 674
DOI 10.1038/s41598-017-00417-z, PubMed 28386069
Optimization of Storage Temperature for Retention of Undifferentiated Cell Character of Cultured Human Epidermal Cell Sheets
Sci Rep, 7 (1), 8206
DOI 10.1038/s41598-017-08586-7, PubMed 28811665
Cultured epidermal stem cells in regenerative medicine
Stem Cell Res Ther, 8 (1), 155
DOI 10.1186/s13287-017-0587-1, PubMed 28676094
Stage-related central corneal epithelial transformation in congenital aniridia-associated keratopathy
Ocul Surf, 16 (1), 163-172
DOI 10.1016/j.jtos.2017.11.003, PubMed 29133179
Reduced Corneal Nerve Fiber Density in Type 2 Diabetes by Wide-Area Mosaic Analysis
Invest Ophthalmol Vis Sci, 58 (14), 6318-6327
DOI 10.1167/iovs.17-22257, PubMed 29242906
The genetics of congenital aniridia-a guide for the ophthalmologist
Surv Ophthalmol, 63 (1), 105-113
DOI 10.1016/j.survophthal.2017.09.004, PubMed 28923585
Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways
Invest Ophthalmol Vis Sci, 58 (11), 4530-4544
DOI 10.1167/iovs.17-21914, PubMed 28892824
Circadian clock and oral cancer
Mol Clin Oncol, 8 (2), 219-226
DOI 10.3892/mco.2017.1518, PubMed 29435282
Interdisciplinary, Comprehensive Oral and Ocular Evaluation of Patients with Primary Sjögren's Syndrome
Sci Rep, 7 (1), 10761
DOI 10.1038/s41598-017-10809-w, PubMed 28883442
Publications 2016
Topography-Guided Transepithelial Surface Ablation in the Treatment of Moderate to High Astigmatism
J Refract Surg, 32 (6), 418-25
DOI 10.3928/1081597X-20160428-01, PubMed 27304606
Epithelial Thickness Profile Change After Combined Topography-Guided Transepithelial Photorefractive Keratectomy and Corneal Cross-linking in Treatment of Keratoconus
J Refract Surg, 32 (9), 626-34
DOI 10.3928/1081597X-20160531-02, PubMed 27598733
The Silk-protein Sericin Induces Rapid Melanization of Cultured Primary Human Retinal Pigment Epithelial Cells by Activating the NF-κB Pathway
Sci Rep, 6, 22671
DOI 10.1038/srep22671, PubMed 26940175
Dry Eye Disease Patients with Xerostomia Report Higher Symptom Load and Have Poorer Meibum Expressibility
PLoS One, 11 (5), e0155214
DOI 10.1371/journal.pone.0155214, PubMed 27148875
Artificial Polymeric Scaffolds as Extracellular Matrix Substitutes for Autologous Conjunctival Goblet Cell Expansion
Invest Ophthalmol Vis Sci, 57 (14), 6134-6146
DOI 10.1167/iovs.16-20081, PubMed 27832279
Evaluation of Equivalent Keratometry Readings Obtained by Pentacam HR (High Resolution)
PLoS One, 11 (3), e0150121
DOI 10.1371/journal.pone.0150121, PubMed 26950834
Nucleus Morphometry in Cultured Epithelial Cells Correlates with Phenotype
Microsc Microanal, 22 (3), 612-20
DOI 10.1017/S1431927616000830, PubMed 27329312
MicroRNAs: Modulators of Tooth Development
Microrna, 5 (2), 132-139
DOI 10.2174/2211536605666160706003256, PubMed 27397033
The Three Paralogous MicroRNA Clusters in Development and Disease, miR-17-92, miR-106a-363, and miR-106b-25
Scientifica (Cairo), 2016, 1379643
DOI 10.1155/2016/1379643, PubMed 27127675
Erratum to: Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease
Neurochem Res, 41 (6), 1237
DOI 10.1007/s11064-016-1916-y, PubMed 27113043
Circadian rhythms and gene expression during mouse molar tooth development
Acta Odontol Scand, 75 (2), 144-153
DOI 10.1080/00016357.2016.1271999, PubMed 28030993
Corneal Nerve Regeneration After Collagen Cross-Linking Treatment of Keratoconus: A 5-Year Longitudinal Study
JAMA Ophthalmol, 134 (1), 70-8
DOI 10.1001/jamaophthalmol.2015.4518, PubMed 26562763
Impact of Storage Temperature on the Expression of Cell Survival Genes in Cultured ARPE-19 Cells
Curr Eye Res, 42 (1), 134-144
DOI 10.3109/02713683.2016.1145236, PubMed 27259952
Electrical Stimulation as a Means for Improving Vision
Am J Pathol, 186 (11), 2783-2797
DOI 10.1016/j.ajpath.2016.07.017, PubMed 27643530
Regulatory roles of microRNAs in human dental tissues
Gene, 596, 9-18
DOI 10.1016/j.gene.2016.10.009, PubMed 27725267
Alteration in cellular turnover and progenitor cell population in lacrimal glands from thrombospondin 1-/- mice, a model of dry eye
Exp Eye Res, 153, 27-41
DOI 10.1016/j.exer.2016.09.011, PubMed 27697548
Storage Temperature Alters the Expression of Differentiation-Related Genes in Cultured Oral Keratinocytes
PLoS One, 11 (3), e0152526
DOI 10.1371/journal.pone.0152526, PubMed 27023475
Transcriptome Analysis of Cultured Limbal Epithelial Cells on an Intact Amniotic Membrane following Hypothermic Storage in Optisol-GS
J Funct Biomater, 7 (1)
DOI 10.3390/jfb7010004, PubMed 26901233
Culture of Oral Mucosal Epithelial Cells for the Purpose of Treating Limbal Stem Cell Deficiency
J Funct Biomater, 7 (1)
DOI 10.3390/jfb7010005, PubMed 26938569
Assessment of refractive astigmatism and simulated therapeutic refractive surgery strategies in coma-like-aberrations-dominant corneal optics
Eye Vis (Lond), 3, 13
DOI 10.1186/s40662-016-0044-8, PubMed 27175371
Publications 2015
Xenobiotic- and Serum-Free Culture of Oral Mucosal Epithelial Cells on Contact Lenses
Curr Eye Res, 41 (1), 20-7
DOI 10.3109/02713683.2015.1004720, PubMed 25658020
Corneal collagen cross-linking (CXL) in thin corneas
Eye Vis (Lond), 2, 15
DOI 10.1186/s40662-015-0025-3, PubMed 26605368
Postoperative Changes in Corneal Epithelial and Stromal Thickness Profiles After Photorefractive Keratectomy in Treatment of Myopia
J Refract Surg, 31 (7), 446-53
DOI 10.3928/1081597X-20150623-02, PubMed 26186563
Concise Review: Comparison of Culture Membranes Used for Tissue Engineered Conjunctival Epithelial Equivalents
J Funct Biomater, 6 (4), 1064-84
DOI 10.3390/jfb6041064, PubMed 26690486
Keratometric index obtained by Fourier-domain optical coherence tomography
PLoS One, 10 (4), e0122441
DOI 10.1371/journal.pone.0122441, PubMed 25886489
Effect of Storage Temperature on Structure and Function of Cultured Human Oral Keratinocytes
PLoS One, 10 (6), e0128306
DOI 10.1371/journal.pone.0128306, PubMed 26052937
Effect of Storage Temperature on the Phenotype of Cultured Epidermal Cells Stored in Xenobiotic-Free Medium
Curr Eye Res, 41 (6), 757-68
DOI 10.3109/02713683.2015.1062113, PubMed 26398483
Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease
Neurochem Res, 41 (6), 1229-36
DOI 10.1007/s11064-015-1792-x, PubMed 26677077
Focused Tortuosity Definitions Based on Expert Clinical Assessment of Corneal Subbasal Nerves
Invest Ophthalmol Vis Sci, 56 (9), 5102-9
DOI 10.1167/iovs.15-17284, PubMed 26241397
Substrates for Expansion of Corneal Endothelial Cells towards Bioengineering of Human Corneal Endothelium
J Funct Biomater, 6 (3), 917-45
DOI 10.3390/jfb6030917, PubMed 26378588
Effect of Storage Temperature on Key Functions of Cultured Retinal Pigment Epithelial Cells
J Ophthalmol, 2015, 263756
DOI 10.1155/2015/263756, PubMed 26448872
Autofluorescence imaging in the differential diagnosis of optic disc melanocytoma
Acta Ophthalmol, 93 (5), 476-480
DOI 10.1111/aos.12725, PubMed 25923254
Pre-Clinical Cell-Based Therapy for Limbal Stem Cell Deficiency
J Funct Biomater, 6 (3), 863-88
DOI 10.3390/jfb6030863, PubMed 26343740
Serum-free and xenobiotic-free preservation of cultured human limbal epithelial cells
PLoS One, 10 (3), e0118517
DOI 10.1371/journal.pone.0118517, PubMed 25734654
Concise review: transplantation of cultured oral mucosal epithelial cells for treating limbal stem cell deficiency-current status and future perspectives
Stem Cells, 33 (6), 1685-95
DOI 10.1002/stem.1999, PubMed 25786664
Publications 2014
Reliability of corneal dynamic scheimpflug analyser measurements in virgin and post-PRK eyes
PLoS One, 9 (10), e109577
DOI 10.1371/journal.pone.0109577, PubMed 25302580
Objective assessment of changes in nuclear morphology and cell distribution following induction of apoptosis
Diagn Pathol, 9, 92
DOI 10.1186/1746-1596-9-92, PubMed 24885713
The impact of storage temperature on the morphology, viability, cell number and metabolism of cultured human conjunctival epithelium
Curr Eye Res, 40 (1), 30-9
DOI 10.3109/02713683.2014.909497, PubMed 24750037
Effect of storage temperature on cultured epidermal cell sheets stored in xenobiotic-free medium
PLoS One, 9 (8), e105808
DOI 10.1371/journal.pone.0105808, PubMed 25170754
Antioxidants Improve the Viability of Stored Adult Retinal Pigment Epithelial-19 Cultures
Ophthalmol Ther, 3 (1-2), 49-61
DOI 10.1007/s40123-014-0024-9, PubMed 25134496
Corneal collagen cross-linking with and without epithelial removal: a contralateral study with 0.5% hypotonic riboflavin solution
Biomed Res Int, 2014, 619398
DOI 10.1155/2014/619398, PubMed 25050368
RTQUAKE, A Real-Time Earthquake Detection System Integrated with SEISAN
Seismol. Res. Lett., 85 (3), 735-742
DOI 10.1785/0220130175
Publications 2013
Cataract development in Norwegian patients with congenital aniridia
Acta Ophthalmol, 92 (2), e165-7
DOI 10.1111/aos.12225, PubMed 23826968
miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium
Exp Eye Res, 115, 189-98
DOI 10.1016/j.exer.2013.07.003, PubMed 23872359
In vivo morphology of the limbal palisades of vogt correlates with progressive stem cell deficiency in aniridia-related keratopathy
Invest Ophthalmol Vis Sci, 54 (8), 5333-42
DOI 10.1167/iovs.13-11780, PubMed 23860752
Correlation of cytokine levels and microglial cell infiltration during retinal degeneration in RCS rats
PLoS One, 8 (12), e82061
DOI 10.1371/journal.pone.0082061, PubMed 24349184
Standardized baseline human corneal subbasal nerve density for clinical investigations with laser-scanning in vivo confocal microscopy
Invest Ophthalmol Vis Sci, 54 (10), 7091-102
DOI 10.1167/iovs.13-12999, PubMed 24084094
Optimization of Storage Temperature for Cultured ARPE-19 Cells
J Ophthalmol, 2013, 216359
DOI 10.1155/2013/216359, PubMed 24251032
One-step transepithelial topography-guided ablation in the treatment of myopic astigmatism
PLoS One, 8 (6), e66618
DOI 10.1371/journal.pone.0066618, PubMed 23799124
Limbal epithelial cell therapy: past, present, and future
Methods Mol Biol, 1014, 3-43
DOI 10.1007/978-1-62703-432-6_1, PubMed 23690002
The culture of limbal epithelial cells
Methods Mol Biol, 1014, 103-29
DOI 10.1007/978-1-62703-432-6_7, PubMed 23690008
Publications 2012
Effect of limbal marking prior to laser ablation on the magnitude of cyclotorsional error
J Refract Surg, 28 (5), 358-62
DOI 10.3928/1081597X-20120221-02, PubMed 22421093
Effect of biopsy location and size on proliferative capacity of ex vivo expanded conjunctival tissue
Invest Ophthalmol Vis Sci, 53 (6), 2897-903
DOI 10.1167/iovs.11-8269, PubMed 22491407
Biopsy harvesting site and distance from the explant affect conjunctival epithelial phenotype ex vivo
Exp Eye Res, 104, 15-25
DOI 10.1016/j.exer.2012.09.007, PubMed 23022405
Safety and efficacy of epithelium-on corneal collagen cross-linking using a multifactorial approach to achieve proper stromal riboflavin saturation
J Ophthalmol, 2012, 498435
DOI 10.1155/2012/498435, PubMed 22900147
Late onset post-LASIK keratectasia with reversal and stabilization after use of latanoprost and corneal collagen cross-linking
Eye Rep., 2 (1), e2-9
DOI 10.4081/eye.2012.e2
Publications 2011
Transepithelial, Topography-guided Ablation in the Treatment of Visual Disturbances in LASIK Flap or Interface Complications
J Refract Surg, 28 (2), 120-6
DOI 10.3928/1081597X-20110926-01, PubMed 21974725
Effects of serum-free storage on morphology, phenotype, and viability of ex vivo cultured human conjunctival epithelium
Exp Eye Res, 94 (1), 109-16
DOI 10.1016/j.exer.2011.11.015, PubMed 22154551
Publications 2010
The impact of de-epithelialization of the amniotic membrane matrix on morphology of cultured human limbal epithelial cells subject to eye bank storage
Cornea, 29 (4), 439-45
DOI 10.1097/ICO.0b013e3181ba0c94, PubMed 20164752
Novel technology in regenerative medicine: eye bank storage of limbal explant cultures for transplantation
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 933, 1 b. (flere pag.)
BIBSYS 101143389, ISBN 978-82-8072-954-5
Publications 2009
Comparison of the histology, gene expression profile, and phenotype of cultured human limbal epithelial cells from different limbal regions
Invest Ophthalmol Vis Sci, 50 (11), 5165-72
DOI 10.1167/iovs.08-2884, PubMed 19578011
Sterility control and long-term eye-bank storage of cultured human limbal epithelial cells for transplantation
Br J Ophthalmol, 93 (7), 980-3
DOI 10.1136/bjo.2008.149591, PubMed 19211610
Publications 2008
Apolipoprotein E genotype and risk for development of cataract and age-related macular degeneration
Acta Ophthalmol, 86 (4), 401-3
DOI 10.1111/j.1600-0420.2007.01070.x, PubMed 18498549
Publications 2007
Effect of limbal explant orientation on the histology, phenotype, ultrastructure and barrier function of cultured limbal epithelial cells
Acta Ophthalmol Scand, 85 (4), 377-86
DOI 10.1111/j.1600-0420.2006.00873.x, PubMed 17263847
Effects of organ culture and Optisol-GS storage on structural integrity, phenotypes, and apoptosis in cultured corneal epithelium
Invest Ophthalmol Vis Sci, 48 (12), 5484-93
DOI 10.1167/iovs.07-0494, PubMed 18055796
Effects of APOE and CHRNA4 genotypes on retinal nerve fibre layer thickness at the optic disc and on risk for developing exfoliation syndrome
Acta Ophthalmol Scand, 85 (3), 257-61
DOI 10.1111/j.1600-0420.2006.00824.x, PubMed 17488453