Maja Radulovic

  • Project Leader, Senior scientist (Research Council of Norway)
  • +47 22 78 14 91

Maja is in charge of the Project Mechanisms and importance of lysosome repair

From the news:

Highlighted in the journal Science: Fixing leaky lysosomes

Maja Radulovic first author on EMBO J article: An ER for damaged lysosomes

Vietri, Radulovic and Stenmark with Nature Review about ESCRT proteins in membrane dynamics

EMBO J paper from Maja Radulovic: Repair of damaged lysosomes keeps cells alive.

 

Publications 2024

Radulovic M, Stenmark H (2024)
Lysophagy prevents neurotoxic aggregate transmission
Proc Natl Acad Sci U S A, 121 (3), e2321181121
DOI 10.1073/pnas.2321181121, PubMed 38190545

Publications 2023

Kaur N, de la Ballina LR, Haukaas HS, Torgersen ML, Radulovic M, Munson MJ, Sabirsh A, Stenmark H, Simonsen A, Carlsson SR, Lystad AH (2023)
TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
EMBO J, 42 (17), e113105
DOI 10.15252/embj.2022113105, PubMed 37409525

Publications 2022

Radulovic M, Wenzel EM, Gilani S, Holland LK, Lystad AH, Phuyal S, Olkkonen VM, Brech A, Jäättelä M, Maeda K, Raiborg C, Stenmark H (2022)
Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
EMBO J, 41 (24), e112677
DOI 10.15252/embj.2022112677, PubMed 36408828

Publications 2021

Weisheit S, Wegner CS, Ailte I, Radulovic M, Weyergang A, Selbo PK, Brech A (2021)
Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
Biochem Pharmacol, 194, 114837
DOI 10.1016/j.bcp.2021.114837, PubMed 34780750

Zhen Y, Radulovic M, Vietri M, Stenmark H (2021)
Sealing holes in cellular membranes
EMBO J, 40 (7), e106922
DOI 10.15252/embj.2020106922, PubMed 33644904

Publications 2020

Radulovic M, Stenmark H (2020)
LRRK2 to the rescue of damaged endomembranes
EMBO J, 39 (18), e106162
DOI 10.15252/embj.2020106162, PubMed 32803793

Publications 2019

Vietri M, Radulovic M, Stenmark H (2019)
The many functions of ESCRTs
Nat Rev Mol Cell Biol, 21 (1), 25-42
DOI 10.1038/s41580-019-0177-4, PubMed 31705132

Zhen Y, Spangenberg H, Munson MJ, Brech A, Schink KO, Tan KW, Sørensen V, Wenzel EM, Radulovic M, Engedal N, Simonsen A, Raiborg C, Stenmark H (2019)
ESCRT-mediated phagophore sealing during mitophagy
Autophagy, 16 (5), 826-841
DOI 10.1080/15548627.2019.1639301, PubMed 31366282

Publications 2018

Radulovic M, Schink KO, Wenzel EM, Nähse V, Bongiovanni A, Lafont F, Stenmark H (2018)
ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival
EMBO J, 37 (21)
DOI 10.15252/embj.201899753, PubMed 30314966

Radulovic M, Stenmark H (2018)
ESCRTs in membrane sealing
Biochem Soc Trans, 46 (4), 773-778
DOI 10.1042/BST20170435, PubMed 29903934

Visram M, Radulovic M, Steiner S, Malanovic N, Eichmann TO, Wolinski H, Rechberger GN, Tehlivets O (2018)
Homocysteine regulates fatty acid and lipid metabolism in yeast
J Biol Chem, 293 (15), 5544-5555
DOI 10.1074/jbc.M117.809236, PubMed 29414770

Publications 2016

Heier C, Taschler U, Radulovic M, Aschauer P, Eichmann TO, Grond S, Wolinski H, Oberer M, Zechner R, Kohlwein SD, Zimmermann R (2016)
Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism
J Biol Chem, 291 (22), 11865-75
DOI 10.1074/jbc.M115.705541, PubMed 27036938

Publications 2015

Wolinski H, Hofbauer HF, Hellauer K, Cristobal-Sarramian A, Kolb D, Radulovic M, Knittelfelder OL, Rechberger GN, Kohlwein SD (2015)
Seipin is involved in the regulation of phosphatidic acid metabolism at a subdomain of the nuclear envelope in yeast
Biochim Biophys Acta, 1851 (11), 1450-64
DOI 10.1016/j.bbalip.2015.08.003, PubMed 26275961

Publications 2013

Radulovic M, Knittelfelder O, Cristobal-Sarramian A, Kolb D, Wolinski H, Kohlwein SD (2013)
The emergence of lipid droplets in yeast: current status and experimental approaches
Curr Genet, 59 (4), 231-42
DOI 10.1007/s00294-013-0407-9, PubMed 24057105