Publications 2025

Jonsson A, López-Porras A, Nørstebø SF, Guslund NC, Sørum H, Qiao SW, Johansen FE (2025)
Protective IgM-mediated immunity against Vibrio anguillarum in Atlantic cod with evolutionary losses of mhc class II and cd4
16, 1579541
DOI 10.3389/fimmu.2025.1579541, PubMed 40672951

López-Porras A, Jonsson A, Qiao SW, Johansen FE (2025)
Sustained T cell-independent type 2 antibody response in a naturally MHC II-deficient teleost fish
164, 105330
DOI 10.1016/j.dci.2025.105330, PubMed 39892681

Publications 2024

Risnes LF, Reims HM, Doyle RM, Qiao SW, Sollid LM, Lundin KEA, Christophersen A (2024)
Gluten-Free Diet Induces Rapid Changes in Phenotype and Survival Properties of Gluten-Specific T Cells in Celiac Disease
167 (2), 250-263
DOI 10.1053/j.gastro.2024.03.027, PubMed 38552723

Publications 2023

Resseguier J, Nguyen-Chi M, Wohlmann J, Rigaudeau D, Salinas I, Oehlers SH, Wiegertjes GF, Johansen FE, Qiao SW, Koppang EO, Verrier B, Boudinot P, Griffiths G (2023)
Identification of a pharyngeal mucosal lymphoid organ in zebrafish and other teleosts: Tonsils in fish?
9 (44), eadj0101
DOI 10.1126/sciadv.adj0101, PubMed 37910624

Publications 2022

Dahal-Koirala S, Balaban G, Neumann RS, Scheffer L, Lundin KEA, Greiff V, Sollid LM, Qiao SW, Sandve GK (2022)
TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences
23 (2)
DOI 10.1093/bib/bbab566, PubMed 35062022

Guslund NC, Krabberød AK, Nørstebø SF, Solbakken MH, Jakobsen KS, Johansen FE, Qiao SW (2022)
Lymphocyte subsets in Atlantic cod (Gadus morhua) interrogated by single-cell sequencing
5 (1), 689
DOI 10.1038/s42003-022-03645-w, PubMed 35821077

Lindeman I, Polak J, Qiao SW, Holmøy T, Høglund RA, Vartdal F, Berg-Hansen P, Sollid LM, Lossius A (2022)
Stereotyped B-cell responses are linked to IgG constant region polymorphisms in multiple sclerosis
52 (4), 550-565
DOI 10.1002/eji.202149576, PubMed 35094395

Sudworth A, Segers FM, Yilmaz B, Guslund NC, Macpherson AJ, Dissen E, Qiao SW, Inngjerdingen M (2022)
Innate lymphoid cell characterization in the rat and their correlation to gut commensal microbes
52 (5), 717-729
DOI 10.1002/eji.202149639, PubMed 35099074

Publications 2021

Bakker OB, Ramírez-Sánchez AD, Borek ZA, de Klein N, Li Y, Modderman R, Kooy-Winkelaar Y, Johannesen MK, Matarese F, Martens JHA, Kumar V, van Bergen J, Qiao SW, Lundin KEA, Sollid LM, Koning F, Wijmenga C, Withoff S, Jonkers IH (2021)
Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells
11 (1), 9252
DOI 10.1038/s41598-021-86612-5, PubMed 33927210

Dahal-Koirala S, Risnes LF, Neumann RS, Christophersen A, Lundin KEA, Sandve GK, Qiao SW, Sollid LM (2021)
Comprehensive Analysis of CDR3 Sequences in Gluten-Specific T-Cell Receptors Reveals a Dominant R-Motif and Several New Minor Motifs
12, 639672
DOI 10.3389/fimmu.2021.639672, PubMed 33927715

Lindeman I, Zhou C, Eggesbø LM, Miao Z, Polak J, Lundin KEA, Jahnsen J, Qiao SW, Iversen R, Sollid LM (2021)
Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells
218 (2)
DOI 10.1084/jem.20200852, PubMed 33095260

Qiao SW, Dahal-Koirala S, Eggesbø LM, Lundin KEA, Sollid LM (2021)
Frequency of Gluten-Reactive T Cells in Active Celiac Lesions Estimated by Direct Cell Cloning
12, 646163
DOI 10.3389/fimmu.2021.646163, PubMed 33796112

Sikkeland LIB, Qiao SW, Ueland T, Myrdal O, Wyrozemski L, Aukrust P, Jahnsen FL, Sjaheim T, Kongerud J, Molberg O, Lund MB, Baekkevold ES (2021)
Lung CD4+T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-gamma
Eur. Resp. J., 57 (3), 2000983
DOI 10.1183/13993003.00983-2020

van der Graaf A, Zorro MM, Claringbould A, Võsa U, Aguirre-Gamboa R, Li C, Mooiweer J, Ricaño-Ponce I, Borek Z, Koning F, Kooy-Winkelaar Y, Sollid LM, Qiao SW, Kumar V, Li Y, Franke L, Withoff S, Wijmenga C, Sanna S, Jonkers I, BIOS Consortium (2021)
Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease
11, 562434
DOI 10.3389/fgene.2020.562434, PubMed 33569077

Wyrożemski Ł, Qiao SW (2021)
Immunobiology and conflicting roles of the human CD161 receptor in T cells
94 (3), e13090
DOI 10.1111/sji.13090, PubMed 35611672

Wyrożemski Ł, Sollid LM, Qiao SW (2021)
C-type lectin-like CD161 is not a co-signalling receptor in gluten-reactive CD4 + T cells
93 (6), e13016
DOI 10.1111/sji.13016, PubMed 33368526

Yao Y, Wyrozżemski Ł, Lundin KEA, Sandve GK, Qiao SW (2021)
Differential expression profile of gluten-specific T cells identified by single-cell RNA-seq
16 (10), e0258029
DOI 10.1371/journal.pone.0258029, PubMed 34618841

Publications 2020

du Pré MF, Blazevski J, Dewan AE, Stamnaes J, Kanduri C, Sandve GK, Johannesen MK, Lindstad CB, Hnida K, Fugger L, Melino G, Qiao SW, Sollid LM (2020)
B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2
217 (2)
DOI 10.1084/jem.20190860, PubMed 31727780

Guslund NC, Solbakken MH, Brieuc MSO, Jentoft S, Jakobsen KS, Qiao SW (2020)
Single-Cell Transcriptome Profiling of Immune Cell Repertoire of the Atlantic Cod Which Naturally Lacks the Major Histocompatibility Class II System
11, 559555
DOI 10.3389/fimmu.2020.559555, PubMed 33154745

Lindstad CB, Qiao SW, Johannesen MK, Fugger L, Sollid LM, du Pré MF (2020)
Characterization of T-cell receptor transgenic mice recognizing immunodominant HLA-DQ2.5-restricted gluten epitopes
51 (4), 1002-1005
DOI 10.1002/eji.202048859, PubMed 33368209

Ting YT, Dahal-Koirala S, Kim HSK, Qiao SW, Neumann RS, Lundin KEA, Petersen J, Reid HH, Sollid LM, Rossjohn J (2020)
A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease
117 (6), 3063-3073
DOI 10.1073/pnas.1914308117, PubMed 31974305

Yao Y, Zia A, Neumann RS, Pavlovic M, Balaban G, Lundin KEA, Sandve GK, Qiao SW (2020)
T cell receptor repertoire as a potential diagnostic marker for celiac disease
222, 108621
DOI 10.1016/j.clim.2020.108621, PubMed 33197618

Publications 2019

Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Richter L, Phung D, Greiff V, Risnes LF, Yao Y, Neumann RS, Yaqub S, Øyen O, Horneland R, Aandahl EM, Paulsen V, Sollid LM, Qiao SW, Baekkevold ES, Jahnsen FL (2019)
Resident memory CD8 T cells persist for years in human small intestine
216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737

Goel G, Tye-Din JA, Qiao SW, Russell AK, Mayassi T, Ciszewski C, Sarna VK, Wang S, Goldstein KE, Dzuris JL, Williams LJ, Xavier RJ, Lundin KEA, Jabri B, Sollid LM, Anderson RP (2019)
Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease
5 (8), eaaw7756
DOI 10.1126/sciadv.aaw7756, PubMed 31457091

Hung SC, Hou T, Jiang W, Wang N, Qiao SW, Chow IT, Liu X, van der Burg SH, Koelle DM, Kwok WW, Sollid LM, Mellins ED (2019)
Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense
202 (9), 2558-2569
DOI 10.4049/jimmunol.1801454, PubMed 30926644

Qiao SW, Sollid LM (2019)
Two novel HLA-DQ2.5-restricted gluten T cell epitopes in the DQ2.5-glia-γ4 epitope family
71 (10), 665-667
DOI 10.1007/s00251-019-01138-5, PubMed 31673720

Sollid LM, Tye-Din JA, Qiao SW, Anderson RP, Gianfrani C, Koning F (2019)
Update 2020: nomenclature and listing of celiac disease-relevant gluten epitopes recognized by CD4⁺ T cells
72 (1-2), 85-88
DOI 10.1007/s00251-019-01141-w, PubMed 31735991

Publications 2018

Dahal-Koirala S, Ciacchi L, Petersen J, Risnes LF, Neumann RS, Christophersen A, Lundin KEA, Reid HH, Qiao SW, Rossjohn J, Sollid LM (2018)
Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes
294 (3), 941-952
DOI 10.1074/jbc.RA118.005736, PubMed 30455354

Høydahl LS, Richter L, Frick R, Snir O, Gunnarsen KS, Landsverk OJB, Iversen R, Jeliazkov JR, Gray JJ, Bergseng E, Foss S, Qiao SW, Lundin KEA, Jahnsen J, Jahnsen FL, Sandlie I, Sollid LM, Løset GÅ (2018)
Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease
156 (5), 1428-1439.e10
DOI 10.1053/j.gastro.2018.12.013, PubMed 30593798

Lindeman I, Emerton G, Mamanova L, Snir O, Polanski K, Qiao SW, Sollid LM, Teichmann SA, Stubbington MJT (2018)
BraCeR: B-cell-receptor reconstruction and clonality inference from single-cell RNA-seq
15 (8), 563-565
DOI 10.1038/s41592-018-0082-3, PubMed 30065371

Risnes LF, Christophersen A, Dahal-Koirala S, Neumann RS, Sandve GK, Sarna VK, Lundin KE, Qiao SW, Sollid LM (2018)
Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease
128 (6), 2642-2650
DOI 10.1172/JCI98819, PubMed 29757191

Yao Y, Zia A, Wyrozemski L, Lindeman I, Sandve GK, Qiao SW (2018)
Exploiting antigen receptor information to quantify index switching in single-cell transcriptome sequencing experiments
PLoS One, 13 (12), e0208484
DOI 10.1371/journal.pone.0208484

Publications 2017

Gunnarsen KS, Høydahl LS, Risnes LF, Dahal-Koirala S, Neumann RS, Bergseng E, Frigstad T, Frick R, du Pré MF, Dalhus B, Lundin KE, Qiao SW, Sollid LM, Sandlie I, Løset GÅ (2017)
A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions
2 (17)
DOI 10.1172/jci.insight.95193, PubMed 28878121

Ráki M, Dahal-Koirala S, Yu H, Korponay-Szabó IR, Gyimesi J, Castillejo G, Jahnsen J, Qiao SW, Sollid LM (2017)
Similar Responses of Intestinal T Cells From Untreated Children and Adults With Celiac Disease to Deamidated Gluten Epitopes
153 (3), 787-798.e4
DOI 10.1053/j.gastro.2017.05.016, PubMed 28535873

Sarna VK, Lundin KEA, Mørkrid L, Qiao SW, Sollid LM, Christophersen A (2017)
HLA-DQ-Gluten Tetramer Blood Test Accurately Identifies Patients With and Without Celiac Disease in Absence of Gluten Consumption
154 (4), 886-896.e6
DOI 10.1053/j.gastro.2017.11.006, PubMed 29146521

Publications 2016

Christophersen A, Risnes LF, Bergseng E, Lundin KE, Sollid LM, Qiao SW (2016)
Healthy HLA-DQ2.5+ Subjects Lack Regulatory and Memory T Cells Specific for Immunodominant Gluten Epitopes of Celiac Disease
196 (6), 2819-26
DOI 10.4049/jimmunol.1501152, PubMed 26895834

Dahal-Koirala S, Risnes LF, Christophersen A, Sarna VK, Lundin KE, Sollid LM, Qiao SW (2016)
TCR sequencing of single cells reactive to DQ2.5-glia-α2 and DQ2.5-glia-ω2 reveals clonal expansion and epitope-specific V-gene usage
9 (3), 587-96
DOI 10.1038/mi.2015.147, PubMed 26838051

Publications 2015

Lundin KE, Qiao SW, Snir O, Sollid LM (2015)
Coeliac disease - from genetic and immunological studies to clinical applications
50 (6), 708-17
DOI 10.3109/00365521.2015.1030766, PubMed 25846940

Rath T, Baker K, Dumont JA, Peters RT, Jiang HY, Qiao SW, Lencer WI, Pierce GF, Blumberg RS (2015)
Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics
Crit. Rev. Biotechnol., 35 (2), 235-254
DOI 10.3109/07388551.2013.834293

Sollid LM, Iversen R, Steinsbø Ø, Qiao SW, Bergseng E, Dørum S, du Pré MF, Stamnaes J, Christophersen A, Cardoso I, Hnida K, Chen X, Snir O, Lundin KEA (2015)
Small bowel, celiac disease and adaptive immunity
33 (2), 115-121
DOI 10.1159/000369512, PubMed 25925911

Publications 2014

Christophersen A, Ráki M, Bergseng E, Lundin KE, Jahnsen J, Sollid LM, Qiao SW (2014)
Tetramer-visualized gluten-specific CD4+ T cells in blood as a potential diagnostic marker for coeliac disease without oral gluten challenge
2 (4), 268-78
DOI 10.1177/2050640614540154, PubMed 25083284

Dørum S, Bodd M, Fallang LE, Bergseng E, Christophersen A, Johannesen MK, Qiao SW, Stamnaes J, de Souza GA, Sollid LM (2014)
HLA-DQ molecules as affinity matrix for identification of gluten T cell epitopes
193 (9), 4497-506
DOI 10.4049/jimmunol.1301466, PubMed 25261484

Publications 2013

Qiao SW, Christophersen A, Lundin KE, Sollid LM (2013)
Biased usage and preferred pairing of α- and β-chains of TCRs specific for an immunodominant gluten epitope in coeliac disease
26 (1), 13-9
DOI 10.1093/intimm/dxt037, PubMed 24038601

Rath T, Kuo TT, Baker K, Qiao SW, Kobayashi K, Yoshida M, Roopenian D, Fiebiger E, Lencer WI, Blumberg RS (2013)
The Immunologic Functions of the Neonatal Fc Receptor for IgG
J. Clin. Immunol., 33 1, S9-S17
DOI 10.1007/s10875-012-9768-y

Publications 2012

Di Niro R, Mesin L, Zheng NY, Stamnaes J, Morrissey M, Lee JH, Huang M, Iversen R, du Pré MF, Qiao SW, Lundin KE, Wilson PC, Sollid LM (2012)
High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
18 (3), 441-5
DOI 10.1038/nm.2656, PubMed 22366952

Qiao SW, Iversen R, Ráki M, Sollid LM (2012)
The adaptive immune response in celiac disease
34 (4), 523-40
DOI 10.1007/s00281-012-0314-z, PubMed 22535446

Sollid LM, Qiao SW, Anderson RP, Gianfrani C, Koning F (2012)
Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules
64 (6), 455-60
DOI 10.1007/s00251-012-0599-z, PubMed 22322673

Publications 2011

Baker K, Qiao SW, Kuo TT, Aveson VG, Platzer B, Andersen JT, Sandlie I, Chen ZG, de Haar C, Lencer WI, Fiebiger E, Blumberg RS (2011)
Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8(-)CD11b(+) dendritic cells
Proc. Natl. Acad. Sci. U. S. A., 108 (24), 9927-9932
DOI 10.1073/pnas.1019037108

Qiao SW, Ráki M, Gunnarsen KS, Løset GÅ, Lundin KE, Sandlie I, Sollid LM (2011)
Posttranslational modification of gluten shapes TCR usage in celiac disease
187 (6), 3064-71
DOI 10.4049/jimmunol.1101526, PubMed 21849672

Rauhavirta T, Qiao SW, Jiang Z, Myrsky E, Loponen J, Korponay-Szabo IR, Salovaara H, Garcia-Horsman JA, Venalainen J, Mannisto PT, Collighan R, Mongeot A, Griffin M, Maki M, Kaukinen K, Lindfors K (2011)
Epithelial transport and deamidation of gliadin peptides: a role for coeliac disease patient immunoglobulin A
Clin. Exp. Immunol., 164 (1), 127-136
DOI 10.1111/j.1365-2249.2010.04317.x

Publications 2010

Dørum S, Arntzen MØ, Qiao SW, Holm A, Koehler CJ, Thiede B, Sollid LM, Fleckenstein B (2010)
The preferred substrates for transglutaminase 2 in a complex wheat gluten digest are Peptide fragments harboring celiac disease T-cell epitopes
5 (11), e14056
DOI 10.1371/journal.pone.0014056, PubMed 21124911

Kuo TT, Baker K, Yoshida M, Qiao SW, Aveson VG, Lencer WI, Blumberg RS (2010)
Neonatal Fc Receptor: From Immunity to Therapeutics
J. Clin. Immunol., 30 (6), 777-789
DOI 10.1007/s10875-010-9468-4

Publications 2009

Baker K, Qiao SW, Kuo T, Kobayashi K, Yoshida M, Lencer WI, Blumberg RS (2009)
Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn
Semin. Immunopathol., 31 (2), 223-236
DOI 10.1007/s00281-009-0160-9

Dørum S, Qiao SW, Sollid LM, Fleckenstein B (2009)
A quantitative analysis of transglutaminase 2-mediated deamidation of gluten peptides: implications for the T-cell response in celiac disease
8 (4), 1748-55
DOI 10.1021/pr800960n, PubMed 19239248

Kobayashi K, Qiao SW, Yoshida M, Baker K, Lencer WI, Blumberg RS (2009)
An FcRn-Dependent Role for Anti-flagellin Immunoglobulin G in Pathogenesis of Colitis in Mice
Gastroenterology, 137 (5), 1746-1756
DOI 10.1053/j.gastro.2009.07.059

Qiao SW, Sollid LM, Blumberg RS (2009)
Antigen presentation in celiac disease
21 (1), 111-7
DOI 10.1016/j.coi.2009.03.004, PubMed 19342211

Stenman SM, Venäläinen JI, Lindfors K, Auriola S, Mauriala T, Kaukovirta-Norja A, Jantunen A, Laurila K, Qiao SW, Sollid LM, Männisto PT, Kaukinen K, Mäki M (2009)
Enzymatic detoxification of gluten by germinating wheat proteases: implications for new treatment of celiac disease
41 (5), 390-400
DOI 10.1080/07853890902878138, PubMed 19353359

Publications 2008

Qiao SW, Kobayashi K, Johansen FE, Sollid LM, Andersen JT, Milford E, Roopenian DC, Lencer WI, Blumberg RS (2008)
Dependence of antibody-mediated presentation of antigen on FcRn
105 (27), 9337-42
DOI 10.1073/pnas.0801717105, PubMed 18599440

Publications 2005

Fleckenstein B, Qiao SW, Larsen MR, Roepstorff P, Sollid LM, Jung G (2005)
Molecular characterization of covalent transglutaminase (TG2)-gliadin peptide complexes involved in coeliac disease
Peptides 2004, Proceedings: BRIDGES BETWEEN DISCIPLINES, 73-74

Qiao SW (2005)
On the immune response to gluten in coeliac disease
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 306, 1 b. (flere pag.)
BIBSYS 051151219, ISBN 82-8072-640-3

Qiao SW, Bergseng E, Molberg O, Jung G, Fleckenstein B, Sollid LM (2005)
Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation
175 (1), 254-61
DOI 10.4049/jimmunol.175.1.254, PubMed 15972656

Qiao SW, Piper J, Haraldsen G, Oynebråten I, Fleckenstein B, Molberg O, Khosla C, Sollid LM (2005)
Tissue transglutaminase-mediated formation and cleavage of histamine-gliadin complexes: biological effects and implications for celiac disease
174 (3), 1657-63
DOI 10.4049/jimmunol.174.3.1657, PubMed 15661929

Shan L, Qiao SW, Arentz-Hansen H, Molberg Ø, Gray GM, Sollid LM, Khosla C (2005)
Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue
4 (5), 1732-41
DOI 10.1021/pr050173t, PubMed 16212427

Publications 2004

Fleckenstein B, Qiao SW, Larsen MR, Jung G, Roepstorff P, Sollid LM (2004)
Molecular characterization of covalent complexes between tissue transglutaminase and gliadin peptides
279 (17), 17607-16
DOI 10.1074/jbc.M310198200, PubMed 14747475

Qiao SW, Bergseng E, Molberg Ø, Xia J, Fleckenstein B, Khosla C, Sollid LM (2004)
Antigen presentation to celiac lesion-derived T cells of a 33-mer gliadin peptide naturally formed by gastrointestinal digestion
173 (3), 1757-62
DOI 10.4049/jimmunol.173.3.1757, PubMed 15265905

Publications 2002

Fleckenstein B, Molberg Ø, Qiao SW, Schmid DG, von der Mülbe F, Elgstøen K, Jung G, Sollid LM (2002)
Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process
277 (37), 34109-16
DOI 10.1074/jbc.M204521200, PubMed 12093810