Publications 2024

Szabo A, O'Connell KS, Akkouh IA, Ueland T, Sønderby IE, Hope S, Røe AB, Dønnum MS, Sjaastad I, Steen NE, Ueland T, Sæther LS, Osete JR, Andreassen OA, Nærland T, Djurovic S (2024)
Elevated levels of peripheral and central nervous system immune markers reflect innate immune dysregulation in autism spectrum disorder
Psychiatry Res, 342, 116245 (in press)
DOI 10.1016/j.psychres.2024.116245, PubMed 39481220

Publications 2023

Hope S, Nærland T, Olav Kolset S, Ueland T, Andreassen OA, Nordstrøm M (2023)
Systemic immune profile in Prader-Willi syndrome: elevated matrix metalloproteinase and myeloperoxidase and reduced macrophage inhibitory factor
Orphanet J Rare Dis, 18 (1), 185
DOI 10.1186/s13023-023-02730-5, PubMed 37430349

Hope S, Shadrin AA, Lin A, Bahrami S, Rødevand L, Frei O, Hübenette SJ, Cheng W, Hindley G, Nag H, Ulstein L, Efrim-Budisteanu M, O'Connell K, Dale AM, Djurovic S, Nærland T, Andreassen OA (2023)
Bidirectional genetic overlap between autism spectrum disorder and cognitive traits
Transl Psychiatry, 13 (1), 295
DOI 10.1038/s41398-023-02563-7, PubMed 37709755

Publications 2022

Engh JA, Ueland T, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Hope S, Høegh MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Wedervang-Resell K, Weibell MA, Westlye LT, Djurovic S et al. (2022)
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Schizophr Bull, 48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169

Johannessen J, Nærland T, Hope S, Torske T, Kaale A, Wirgenes KV, Malt E, Djurovic S, Rietschel M, Andreassen OA (2022)
Correction to: Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
Eur J Hum Genet, 30 (10), 1198
DOI 10.1038/s41431-021-01021-6, PubMed 34903869

Sheikh MA, O'Connell KS, Lekva T, Szabo A, Akkouh IA, Osete JR, Agartz I, Engh JA, Andreou D, Boye B, Bøen E, Elvsåshagen T, Hope S, Frogner Werner MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Melle I, Drange OK, Morken G, Nærland T, Sørensen K, Vaaler AE, Weibell MA et al. (2022)
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Biol Psychiatry, 93 (2), 187-196
DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530

Torske T, Nærland T, Quintana DS, Hypher RE, Kaale A, Høyland AL, Hope S, Johannessen J, Øie MG, Andreassen OA (2022)
Sex as a Moderator Between Parent Ratings of Executive Dysfunction and Social Difficulties in Children and Adolescents with Autism Spectrum Disorder
J Autism Dev Disord, 53 (10), 3847-3859
DOI 10.1007/s10803-022-05629-5, PubMed 35838825

Publications 2021

Johannessen J, Nærland T, Hope S, Torske T, Kaale A, Wirgenes KV, Malt E, Djurovic S, Rietschel M, Andreassen OA (2021)
Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
Eur J Hum Genet, 30 (10), 1138-1146
DOI 10.1038/s41431-021-00966-y, PubMed 34776508

Schjelderup J, Hope S, Vatshelle C, van Karnebeek CDM (2021)
Treatment experience in two adults with creatinfe transporter deficiency
Mol Genet Metab Rep, 27, 100731
DOI 10.1016/j.ymgmr.2021.100731, PubMed 33665121

Szabo A, O'Connell KS, Ueland T, Sheikh MA, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Engh JA, Hope S, Collier Høegh M, Joa I, Johnsen E, Kroken RA, Vik Lagerberg T, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Sørensen K et al. (2021)
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
Brain Behav Immun, 99, 299-306
DOI 10.1016/j.bbi.2021.10.017, PubMed 34758379

Publications 2020

Hope S, Naerland T, Høiland AL, Torske T, Malt E, Abrahamsen T, Nerhus M, Wedervang-Resell K, Lonning V, Johannessen J, Steen NE, Agartz I, Stenberg N, Hundhausen T, Mørkrid L, Andreassen OA (2020)
Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia: A comparison among participants between 2 and 53 years
FASEB J, 34 (6), 8114-8124
DOI 10.1096/fj.201900855RRR, PubMed 32323402

Nordstrøm M, Retterstøl K, Hope S, Kolset SO (2020)
Nutritional challenges in children and adolescents with Down syndrome
Lancet Child Adolesc Health, 4 (6), 455-464
DOI 10.1016/S2352-4642(19)30400-6, PubMed 32450124

Reponen EJ, Dieset I, Tesli M, Mørch RH, Aas M, Vedal TSJ, Haug E, Drange OK, Steen NE, Hope S, Szabo A, Gohar SM, Wedervang-Resell K, Djurovic S, Melle I, Aukrust P, Andreassen OA, Ueland T (2020)
Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
Front Psychiatry, 11, 672
DOI 10.3389/fpsyt.2020.00672, PubMed 32754070

Publications 2019

Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S et al. (2019)
Identification of common genetic risk variants for autism spectrum disorder
Nat Genet, 51 (3), 431-444
DOI 10.1038/s41588-019-0344-8, PubMed 30804558

Hassel B, Rogne AG, Hope S (2019)
Intellectual Disability Associated With Pyridoxine-Responsive Epilepsies: The Need to Protect Cognitive Development
Front Psychiatry, 10, 116
DOI 10.3389/fpsyt.2019.00116, PubMed 30930802

Holmøy AKT, Johannessen CH, Hope S, van Walsem MR, Aanonsen NO, Hassel B (2019)
Uncovering health and social care needs among myotonic dystrophy patients: Utility of the Needs and Provisions Complexity Scale
Acta Neurol Scand, 139 (6), 526-532
DOI 10.1111/ane.13086, PubMed 30848487

Mørch RH, Dieset I, Færden A, Reponen EJ, Hope S, Hoseth EZ, Gardsjord ES, Aas M, Iversen T, Joa I, Morken G, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA (2019)
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors
Psychol Med, 49 (10), 1749-1757
DOI 10.1017/S0033291718004142, PubMed 30688187

Mørch RH, Dieset I, Færden A, Reponen EJ, Hope S, Hoseth EZ, Gardsjord ES, Aas M, Iversen T, Joa I, Morken G, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA (2019)
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors - ERRATUM
Psychol Med, 49 (10), 1758
DOI 10.1017/S0033291719000291, PubMed 30803457

Steen NE, Dieset I, Hope S, Vedal TSJ, Smeland OB, Matson W, Kaddurah-Daouk R, Agartz I, Melle I, Djurovic S, Jönsson EG, Bogdanov M, Andreassen OA (2019)
Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders
Psychol Med, 50 (4), 595-606
DOI 10.1017/S0033291719000400, PubMed 30867076

Publications 2018

Hope S, Nordstrom M, Retterstol K, Iversen PO, Kolset SO (2018)
The right to a health promoting diet for people with intellectual disabilities
Tidsskr. Nor. Laegeforen., 138 (2), 122-123

Hope S, Nordstrøm M, Retterstøl K, Iversen PO, Kolset SO (2018)
The right to a health-promoting diet for people with intellectual disabilities
Tidsskr Nor Laegeforen, 138 (2)
DOI 10.4045/tidsskr.17.0985, PubMed 29357630

Hoseth EZ, Krull F, Dieset I, Mørch RH, Hope S, Gardsjord ES, Steen NE, Melle I, Brattbakk HR, Steen VM, Aukrust P, Djurovic S, Andreassen OA, Ueland T (2018)
Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder
Transl Psychiatry, 8 (1), 55
DOI 10.1038/s41398-018-0102-1, PubMed 29507296

Hoseth EZ, Krull F, Dieset I, Mørch RH, Hope S, Gardsjord ES, Steen NE, Melle I, Brattbakk HR, Steen VM, Aukrust P, Djurovic S, Andreassen OA, Ueland T (2018)
Attenuated Notch signaling in schizophrenia and bipolar disorder
Sci Rep, 8 (1), 5349
DOI 10.1038/s41598-018-23703-w, PubMed 29593239

Kolset SO, Nordstrøm M, Hope S, Retterstøl K, Iversen PO (2018)
Securing rights and nutritional health for persons with intellectual disabilities - a pressing challenge
Food Nutr Res, 62
DOI 10.29219/fnr.v62.1268, PubMed 29899685

Aas M, Dieset I, Mørch R, Steen NE, Hope S, Reponen EJ, Laskemoen JF, Ueland T, Aukrust P, Melle I, Agartz I, Andreassen OA (2018)
Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders
Schizophr Res, 205, 45-50
DOI 10.1016/j.schres.2018.08.007, PubMed 30126813

Publications 2017

Hoseth EZ, Ueland T, Dieset I, Birnbaum R, Shin JH, Kleinman JE, Hyde TM, Mørch RH, Hope S, Lekva T, Abraityte AJ, Michelsen AE, Melle I, Westlye LT, Ueland T, Djurovic S, Aukrust P, Weinberger DR, Andreassen OA (2017)
A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue
Schizophr Bull, 43 (4), 881-890
DOI 10.1093/schbul/sbw183, PubMed 28049760

Høyland AL, Øgrim G, Lydersen S, Hope S, Engstrøm M, Torske T, Nærland T, Andreassen OA (2017)
Event-Related Potentials in a Cued Go-NoGo Task Associated with Executive Functions in Adolescents with Autism Spectrum Disorder; A Case-Control Study
Front Neurosci, 11, 393
DOI 10.3389/fnins.2017.00393, PubMed 28744191

Iversen TSJ, Steen NE, Dieset I, Hope S, Mørch R, Gardsjord ES, Jørgensen KN, Melle I, Andreassen OA, Molden E, Jönsson EG (2017)
Side effect burden of antipsychotic drugs in real life - Impact of gender and polypharmacy
Prog Neuropsychopharmacol Biol Psychiatry, 82, 263-271
DOI 10.1016/j.pnpbp.2017.11.004, PubMed 29122637

Johannessen J, Nærland T, Hope S, Torske T, Høyland AL, Strohmaier J, Heiberg A, Rietschel M, Djurovic S, Andreassen OA (2017)
Parents' Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder-Data from a Norwegian Sample
Int J Mol Sci, 18 (5)
DOI 10.3390/ijms18051078, PubMed 28524073

Aas M, Dieset I, Hope S, Hoseth E, Mørch R, Reponen E, Steen NE, Laskemoen JF, Ueland T, Aukrust P, Agartz I, Andreassen OA, Melle I (2017)
Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses
Brain Behav Immun, 65, 342-349
DOI 10.1016/j.bbi.2017.06.005, PubMed 28619247

Publications 2016

Mørch RH, Dieset I, Færden A, Hope S, Aas M, Nerhus M, Gardsjord ES, Joa I, Morken G, Agartz I, Aukrust P, Djurovic S, Melle I, Ueland T, Andreassen OA (2016)
Inflammatory evidence for the psychosis continuum model
Psychoneuroendocrinology, 67, 189-97
DOI 10.1016/j.psyneuen.2016.02.011, PubMed 26923849

Nerhus M, Berg AO, Kvitland LR, Dieset I, Hope S, Dahl SR, Weibell MA, Romm KL, Faerden A, Andreassen OA, Melle I (2016)
Low vitamin D is associated with negative and depressive symptoms in psychotic disorders
Schizophr Res, 178 (1-3), 44-49
DOI 10.1016/j.schres.2016.08.024, PubMed 27595553

Publications 2015

Hope S, Hoseth E, Dieset I, Mørch RH, Aas M, Aukrust P, Djurovic S, Melle I, Ueland T, Agartz I, Ueland T, Westlye LT, Andreassen OA (2015)
Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls
Schizophr Res, 165 (2-3), 188-94
DOI 10.1016/j.schres.2015.04.004, PubMed 25956633

Publications 2014

Dieset I, Haukvik UK, Melle I, Røssberg JI, Ueland T, Hope S, Dale AM, Djurovic S, Aukrust P, Agartz I, Andreassen OA (2014)
Association between altered brain morphology and elevated peripheral endothelial markers--implications for psychotic disorders
Schizophr Res, 161 (2-3), 222-8
DOI 10.1016/j.schres.2014.11.006, PubMed 25433965

Publications 2013

Hope S, Ueland T, Steen NE, Dieset I, Lorentzen S, Berg AO, Agartz I, Aukrust P, Andreassen OA (2013)
Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia and bipolar disorder
Schizophr Res, 145 (1-3), 36-42
DOI 10.1016/j.schres.2012.12.023, PubMed 23403415

Publications 2012

Dieset I, Djurovic S, Tesli M, Hope S, Mattingsdal M, Michelsen A, Joa I, Larsen TK, Agartz I, Melle I, Røssberg JI, Aukrust P, Andreassen OA, Ueland T (2012)
Up-regulation of NOTCH4 gene expression in bipolar disorder
Am J Psychiatry, 169 (12), 1292-300
DOI 10.1176/appi.ajp.2012.11091431, PubMed 23212060

Dieset I, Hope S, Ueland T, Bjella T, Agartz I, Melle I, Aukrust P, Røssberg JI, Andreassen OA (2012)
Cardiovascular risk factors during second generation antipsychotic treatment are associated with increased C-reactive protein
Schizophr Res, 140 (1-3), 169-74
DOI 10.1016/j.schres.2012.06.040, PubMed 22817875

Publications 2011

Hope S, Dieset I, Agartz I, Steen NE, Ueland T, Melle I, Aukrust P, Andreassen OA (2011)
Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia
J Psychiatr Res, 45 (12), 1608-16
DOI 10.1016/j.jpsychires.2011.08.003, PubMed 21889167

Steen NE, Lorentzen S, Barrett EA, Lagerberg TV, Hope S, Larsson S, Berg AO, Agartz I, Melle I, Berg JP, Andreassen OA (2011)
Sex-specific cortisol levels in bipolar disorder and schizophrenia during mental challenge--relationship to clinical characteristics and medication
Prog Neuropsychopharmacol Biol Psychiatry, 35 (4), 1100-7
DOI 10.1016/j.pnpbp.2011.03.008, PubMed 21420462

Steen NE, Methlie P, Lorentzen S, Hope S, Barrett EA, Larsson S, Mork E, Almås B, Løvås K, Agartz I, Melle I, Berg JP, Andreassen OA (2011)
Increased systemic cortisol metabolism in patients with schizophrenia and bipolar disorder: a mechanism for increased stress vulnerability?
J Clin Psychiatry, 72 (11), 1515-21
DOI 10.4088/JCP.10m06068yel, PubMed 21367348

Publications 2010

Hope S, Melle I, Aukrust P, Agartz I, Lorentzen S, Steen NE, Djurovic S, Ueland T, Andreassen OA (2010)
Osteoprotegerin levels in patients with severe mental disorders
J Psychiatry Neurosci, 35 (5), 304-10
DOI 10.1503/jpn.090088, PubMed 20569643

Steen NE, Tesli M, Kähler AK, Methlie P, Hope S, Barrett EA, Larsson S, Mork E, Løvås K, Røssberg JI, Agartz I, Melle I, Djurovic S, Lorentzen S, Berg JP, Andreassen OA (2010)
SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders
Prog Neuropsychopharmacol Biol Psychiatry, 34 (8), 1500-6
DOI 10.1016/j.pnpbp.2010.08.013, PubMed 20800085

Publications 2009

Hope S, Melle I, Aukrust P, Steen NE, Birkenaes AB, Lorentzen S, Agartz I, Ueland T, Andreassen OA (2009)
Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor
Bipolar Disord, 11 (7), 726-34
DOI 10.1111/j.1399-5618.2009.00757.x, PubMed 19839997