Srdjan Djurovic
- Group leader/Professor; PhD
- +47 22 11 98 90
Publications 2024
Toxoplasma gondii infection associated with inflammasome activation and neuronal injury
Sci Rep, 14 (1), 5327
DOI 10.1038/s41598-024-55887-9, PubMed 38438515
The genetic landscape of basal ganglia and implications for common brain disorders
Nat Commun, 15 (1), 8476
DOI 10.1038/s41467-024-52583-0, PubMed 39353893
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
Nat Genet, 56 (11), 2333-2344
DOI 10.1038/s41588-024-01951-z, PubMed 39433889
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
medRxiv
DOI 10.1101/2024.08.13.24311922, PubMed 39371125
Corrigendum to "Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders" [Psychoneuroendocrinology 157 (2023) 106368]
Psychoneuroendocrinology, 162, 106980
DOI 10.1016/j.psyneuen.2024.106980, PubMed 38336601
Bipolar patients display stoichiometric imbalance of gene expression in post-mortem brain samples
Mol Psychiatry, 29 (4), 1128-1138
DOI 10.1038/s41380-023-02398-0, PubMed 38351171
Gene-based burden tests of rare germline variants identify six cancer susceptibility genes
Nat Genet, 56 (11), 2422-2433
DOI 10.1038/s41588-024-01966-6, PubMed 39472694
Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development
Neurobiol Dis, 203, 106750
DOI 10.1016/j.nbd.2024.106750, PubMed 39608471
Dissecting the Shared Genetic Architecture of Common Epilepsies With Cortical Brain Morphology
Neurol Genet, 10 (3), e200143
DOI 10.1212/NXG.0000000000200143, PubMed 38817246
Unraveling the shared genetics of common epilepsies and general cognitive ability
medRxiv
DOI 10.1101/2024.03.25.24304773, PubMed 38585944
Unraveling the shared genetics of common epilepsies and general cognitive ability
Seizure, 122, 105-112
DOI 10.1016/j.seizure.2024.09.016, PubMed 39388989
Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study
Neuropsychopharmacology, 49 (7), 1113-1119
DOI 10.1038/s41386-023-01792-0, PubMed 38184734
How Real-World Data Can Facilitate the Development of Precision Medicine Treatment in Psychiatry
Biol Psychiatry, 96 (7), 543-551
DOI 10.1016/j.biopsych.2024.01.001, PubMed 38185234
Genome-wide association analysis of treatment resistant schizophrenia for variant discovery and polygenic assessment
Hum Genomics, 18 (1), 108
DOI 10.1186/s40246-024-00673-x, PubMed 39334510
Telomere biology and its maintenance in schizophrenia spectrum disorders: Exploring links to cognition
Schizophr Res, 272, 89-95
DOI 10.1016/j.schres.2024.08.011, PubMed 39208769
Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modeling
Proc Natl Acad Sci U S A, 121 (34), e2312511121
DOI 10.1073/pnas.2312511121, PubMed 39141354
Dissecting the genetic overlap between three complex phenotypes with trivariate MiXeR
medRxiv
DOI 10.1101/2024.02.23.24303236, PubMed 38464132
Homozygosity for R47H in TREM2 and the Risk of Alzheimer's Disease
N Engl J Med, 390 (23), 2217-2219
DOI 10.1056/NEJMc2314334, PubMed 38899702
Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci
medRxiv
DOI 10.1101/2024.03.13.24304161, PubMed 38712091
NLRP3 inflammasome mediates astroglial dysregulation of innate and adaptive immune responses in schizophrenia
Brain Behav Immun, 124, 144-156 (in press)
DOI 10.1016/j.bbi.2024.11.030, PubMed 39617069
Elevated levels of peripheral and central nervous system immune markers reflect innate immune dysregulation in autism spectrum disorder
Psychiatry Res, 342, 116245
DOI 10.1016/j.psychres.2024.116245, PubMed 39481220
Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain
Brain Behav Immun, 118, 287-299
DOI 10.1016/j.bbi.2024.03.014, PubMed 38461955
Identification of Novel Genomic Loci for Anxiety and Extensive Genetic Overlap with Psychiatric Disorders
medRxiv
DOI 10.1101/2023.09.01.23294920, PubMed 37693403
Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders
Psychiatry Clin Neurosci, 78 (12), 783-791
DOI 10.1111/pcn.13742, PubMed 39301620
Comorbidity alters the genetic relationship between anxiety disorders and major depression
medRxiv
DOI 10.1101/2024.11.19.24317523, PubMed 39606413
Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study
Nat Commun, 15 (1), 2655
DOI 10.1038/s41467-024-46817-4, PubMed 38531894
Clustering Schizophrenia Genes by Their Temporal Expression Patterns Aids Functional Interpretation
Schizophr Bull, 50 (2), 327-338
DOI 10.1093/schbul/sbad140, PubMed 37824720
Divergent epigenetic responses to perinatal asphyxia in severe mental disorders
Transl Psychiatry, 14 (1), 16
DOI 10.1038/s41398-023-02709-7, PubMed 38191519
Publications 2023
Longitudinal Transcriptomic Analysis of Human Cortical Spheroids Identifies Axonal Dysregulation in the Prenatal Brain as a Mediator of Genetic Risk for Schizophrenia
Biol Psychiatry, 95 (7), 687-698
DOI 10.1016/j.biopsych.2023.08.017, PubMed 37661009
Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia nervosa
Transl Psychiatry, 13 (1), 291
DOI 10.1038/s41398-023-02585-1, PubMed 37658054
No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank
Transl Psychiatry, 13 (1), 61
DOI 10.1038/s41398-023-02358-w, PubMed 36807331
The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study
Lancet Psychiatry, 10 (6), 441-451
DOI 10.1016/S2215-0366(23)00143-8, PubMed 37208114
Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
Nat Commun, 14 (1), 716
DOI 10.1038/s41467-023-36192-x, PubMed 36759603
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors
Am J Psychiatry, 180 (10), 723-738
DOI 10.1176/appi.ajp.21121266, PubMed 37777856
Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system
Neurobiol Dis, 183, 106174
DOI 10.1016/j.nbd.2023.106174, PubMed 37286172
Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders
Psychoneuroendocrinology, 157, 106368
DOI 10.1016/j.psyneuen.2023.106368, PubMed 37659117
Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy
Nat Hum Behav, 7 (9), 1584-1600
DOI 10.1038/s41562-023-01630-9, PubMed 37365406
Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy
BMC Psychiatry, 23 (1), 659
DOI 10.1186/s12888-023-05154-4, PubMed 37674162
Genome-wide analyses reveal shared genetic architecture and novel risk loci between opioid use disorder and general cognitive ability
Drug Alcohol Depend, 256, 111058
DOI 10.1016/j.drugalcdep.2023.111058, PubMed 38244365
Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression
Addict Biol, 28 (6), e13282
DOI 10.1111/adb.13282, PubMed 37252880
Bidirectional genetic overlap between autism spectrum disorder and cognitive traits
Transl Psychiatry, 13 (1), 295
DOI 10.1038/s41398-023-02563-7, PubMed 37709755
Identification of Novel Loci and Cross-Disorder Pleiotropy Through Multi-Ancestry Genome-Wide Analysis of Alcohol Use Disorder in Over One Million Individuals
Res Sq
DOI 10.21203/rs.3.rs-3755915/v1, PubMed 38196616
Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci
Schizophr Bull, 49 (6), 1654-1664
DOI 10.1093/schbul/sbad063, PubMed 37163672
Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders
JAMA Psychiatry, 80 (7), 738-742
DOI 10.1001/jamapsychiatry.2023.1137, PubMed 37163253
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
Schizophr Bull, 49 (3), 635-645
DOI 10.1093/schbul/sbac191, PubMed 36462169
Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders
Brain, 146 (8), 3392-3403
DOI 10.1093/brain/awad038, PubMed 36757824
Telomere length and verbal learning in bipolar disorders
J Affect Disord, 339, 555-560
DOI 10.1016/j.jad.2023.07.087, PubMed 37459977
Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modelling
bioRxiv
DOI 10.1101/2023.06.14.544920, PubMed 37398070
Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia
Psychiatry Res, 325, 115217
DOI 10.1016/j.psychres.2023.115217, PubMed 37146461
Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Nat Commun, 14 (1), 3453
DOI 10.1038/s41467-023-38951-2, PubMed 37301908
Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Nat Commun, 14 (1), 3923
DOI 10.1038/s41467-023-39492-4, PubMed 37400429
Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids
Mol Psychiatry, 28 (7), 3033-3043
DOI 10.1038/s41380-023-01944-0, PubMed 36653674
Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts
Biol Psychiatry, 95 (1), 62-71
DOI 10.1016/j.biopsych.2023.06.008, PubMed 37348803
Psychiatric disorders and brain white matter exhibit genetic overlap implicating developmental and neural cell biology
Mol Psychiatry, 28 (11), 4924-4932
DOI 10.1038/s41380-023-02264-z, PubMed 37759039
Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors
Am J Psychiatry, 180 (11), 815-826
DOI 10.1176/appi.ajp.20220660, PubMed 37752828
The shared genetic risk architecture of neurological and psychiatric disorders: a genome-wide analysis
medRxiv
DOI 10.1101/2023.07.21.23292993, PubMed 37503175
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities
Schizophr Bull, 49 (5), 1345-1354
DOI 10.1093/schbul/sbad082, PubMed 37319439
Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis
Genome Med, 15 (1), 60
DOI 10.1186/s13073-023-01212-4, PubMed 37528461
Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes
Transl Psychiatry, 13 (1), 147
DOI 10.1038/s41398-023-02442-1, PubMed 37147304
Differences in white blood cell proportions between schizophrenia cases and controls are influenced by medication and variations in time of day
Transl Psychiatry, 13 (1), 211
DOI 10.1038/s41398-023-02507-1, PubMed 37330513
The impact of placental genomic risk for schizophrenia and birth asphyxia on brain development
Transl Psychiatry, 13 (1), 343
DOI 10.1038/s41398-023-02639-4, PubMed 37938559
Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders
Sci Rep, 13 (1), 13845
DOI 10.1038/s41598-023-40310-6, PubMed 37620394
Publications 2022
Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response
Schizophr Bull, 48 (1), 190-198
DOI 10.1093/schbul/sbab092, PubMed 34357384
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools
Brain, 145 (1), 142-153
DOI 10.1093/brain/awab267, PubMed 34273149
New insights into the genetic etiology of Alzheimer's disease and related dementias
Nat Genet, 54 (4), 412-436
DOI 10.1038/s41588-022-01024-z, PubMed 35379992
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J. Affect. Disord., 297, 1032-1039
DOI 10.1016/j.jad.2021.08.135
Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood
Mol Psychiatry, 27 (12), 5167-5176
DOI 10.1038/s41380-022-01751-z, PubMed 36100668
Composite immune marker scores associated with severe mental disorders and illness course
Brain Behav Immun Health, 24, 100483
DOI 10.1016/j.bbih.2022.100483, PubMed 35856063
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Schizophr Bull, 48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169
Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation
Am J Psychiatry, 179 (11), 833-843
DOI 10.1176/appi.ajp.21101051, PubMed 36069018
The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis
Am J Med Genet B Neuropsychiatr Genet, 189 (6), 207-218
DOI 10.1002/ajmg.b.32907, PubMed 35841185
Interleukin-18 signaling system links to agitation in severe mental disorders
Psychoneuroendocrinology, 140, 105721
DOI 10.1016/j.psyneuen.2022.105721, PubMed 35301151
Mapping the expression of an ANK3 isoform associated with bipolar disorder in the human brain
Transl Psychiatry, 12 (1), 45
DOI 10.1038/s41398-022-01784-6, PubMed 35091539
Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings
Neuropsychopharmacology, 47 (11), 1883-1891
DOI 10.1038/s41386-022-01401-6, PubMed 35953530
Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers
Acta Neuropathol, 144 (5), 821-842
DOI 10.1007/s00401-022-02454-z, PubMed 36066633
Correction to: Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
Eur J Hum Genet, 30 (10), 1198
DOI 10.1038/s41431-021-01021-6, PubMed 34903869
Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations
J Alzheimers Dis, 88 (4), 1533-1544
DOI 10.3233/JAD-220174, PubMed 35848024
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Biol Psychiatry, 93 (2), 187-196
DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530
Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
Mol Psychiatry, 28 (3), 1284-1292
DOI 10.1038/s41380-022-01924-w, PubMed 36577840
Shared genetic loci between depression and cardiometabolic traits
PLoS Genet, 18 (5), e1010161
DOI 10.1371/journal.pgen.1010161, PubMed 35560157
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Nature, 604 (7906), 502-508
DOI 10.1038/s41586-022-04434-5, PubMed 35396580
Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology
Biol Psychiatry, 92 (4), 291-298
DOI 10.1016/j.biopsych.2021.12.007, PubMed 35164939
Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
Cell Rep, 39 (5), 110790
DOI 10.1016/j.celrep.2022.110790, PubMed 35508131
Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis
Transl Psychiatry, 12 (1), 38
DOI 10.1038/s41398-022-01811-6, PubMed 35082268
Limited association between infections, autoimmune disease and genetic risk and immune activation in severe mental disorders
Prog Neuropsychopharmacol Biol Psychiatry, 116, 110511
DOI 10.1016/j.pnpbp.2022.110511, PubMed 35063598
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 54 (7), 1062
DOI 10.1038/s41588-022-01126-8, PubMed 35726068
Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex
Nat Commun, 13 (1), 7945
DOI 10.1038/s41467-022-35536-3, PubMed 36572698
Publications 2021
Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia
Brain Behav Immun, 94, 235-244
DOI 10.1016/j.bbi.2021.01.037, PubMed 33571628
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
Psychol Med, 53 (4), 1479-1488
DOI 10.1017/S0033291721003056, PubMed 35387700
Genetic loci shared between major depression and intelligence with mixed directions of effect
Nat Hum Behav, 5 (6), 795-801
DOI 10.1038/s41562-020-01031-2, PubMed 33462475
Cardiometabolic risk factors associated with brain age and accelerate brain ageing
Hum Brain Mapp, 43 (2), 700-720
DOI 10.1002/hbm.25680, PubMed 34626047
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J Affect Disord, 295, 1032-1039
DOI 10.1016/j.jad.2021.08.135, PubMed 34706411
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Biol Psychiatry, 91 (1), 102-117
DOI 10.1016/j.biopsych.2021.02.972, PubMed 34099189
Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness
JAMA Psychiatry, 78 (9), 1020-1030
DOI 10.1001/jamapsychiatry.2021.1435, PubMed 34160554
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
Nat Commun, 12 (1), 3417
DOI 10.1038/s41467-021-22491-8, PubMed 34099642
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease
Mol Psychiatry, 26 (10), 5797-5811
DOI 10.1038/s41380-021-01152-8, PubMed 34112972
Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study
Pharmacogenomics J, 21 (5), 574-585
DOI 10.1038/s41397-021-00234-8, PubMed 33824429
Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking
Transl Psychiatry, 11 (1), 466
DOI 10.1038/s41398-021-01576-4, PubMed 34497263
Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
Eur J Hum Genet, 30 (10), 1138-1146
DOI 10.1038/s41431-021-00966-y, PubMed 34776508
Characterisation of age and polarity at onset in bipolar disorder
Br J Psychiatry, 219 (6), 659-669
DOI 10.1192/bjp.2021.102, PubMed 35048876
Dose-dependent transcriptional effects of lithium and adverse effect burden in a psychiatric cohort
Prog Neuropsychopharmacol Biol Psychiatry, 112, 110408
DOI 10.1016/j.pnpbp.2021.110408, PubMed 34320404
Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics
Neuropsychopharmacology, 46 (10), 1788-1801
DOI 10.1038/s41386-021-01023-4, PubMed 34035472
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Nat Genet, 53 (6), 817-829
DOI 10.1038/s41588-021-00857-4, PubMed 34002096
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Biol Psychiatry, 91 (3), 313-327
DOI 10.1016/j.biopsych.2021.05.029, PubMed 34861974
Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes
Biol Psychiatry, 90 (9), 621-631
DOI 10.1016/j.biopsych.2021.07.007, PubMed 34482950
Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank
Psychol Med, 52 (15), 1-11 (in press)
DOI 10.1017/S0033291721000179, PubMed 33653435
Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders
Mol Psychiatry, 26 (11), 6789-6805
DOI 10.1038/s41380-021-01164-4, PubMed 34075196
Identification of pleiotropy at the gene level between psychiatric disorders and related traits
Transl Psychiatry, 11 (1), 410
DOI 10.1038/s41398-021-01530-4, PubMed 34326310
All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors
Front Cell Neurosci, 15, 671549
DOI 10.3389/fncel.2021.671549, PubMed 34122014
Using iPSC Models to Understand the Role of Estrogen in Neuron-Glia Interactions in Schizophrenia and Bipolar Disorder
Cells, 10 (2)
DOI 10.3390/cells10020209, PubMed 33494281
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
Transl Psychiatry, 11 (1), 407
DOI 10.1038/s41398-021-01527-z, PubMed 34301917
Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
Transl Psychiatry, 11 (1), 3
DOI 10.1038/s41398-020-01142-4, PubMed 33414458
A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia
Transl Psychiatry, 11 (1), 554
DOI 10.1038/s41398-021-01681-4, PubMed 34716291
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
Brain Behav Immun, 99, 299-306
DOI 10.1016/j.bbi.2021.10.017, PubMed 34758379
Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs
Hum Brain Mapp, 43 (1), 300-328
DOI 10.1002/hbm.25354, PubMed 33615640
1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans
Transl Psychiatry, 11 (1), 182
DOI 10.1038/s41398-021-01213-0, PubMed 33753722
Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors
Transl Psychiatry, 11 (1), 368
DOI 10.1038/s41398-021-01466-9, PubMed 34226488
Common Genetic Variation and Age of Onset of Anorexia Nervosa
Biol Psychiatry Glob Open Sci, 2 (4), 368-378
DOI 10.1016/j.bpsgos.2021.09.001, PubMed 36324647
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 53 (9), 1276-1282
DOI 10.1038/s41588-021-00921-z, PubMed 34493870
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 53 (12), 1722
DOI 10.1038/s41588-021-00977-x, PubMed 34773122
Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci
Addiction, 117 (3), 600-610
DOI 10.1111/add.15680, PubMed 34472679
Publications 2020
Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
Brain Behav Immun, 87, 634-644
DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548
Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study
JAMA Psychiatry, 77 (5), 503-512
DOI 10.1001/jamapsychiatry.2019.4188, PubMed 31913414
Genetic control of variability in subcortical and intracranial volumes
Mol Psychiatry, 26 (8), 3876-3883
DOI 10.1038/s41380-020-0664-1, PubMed 32047264
Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD
Mol Autism, 11 (1), 42
DOI 10.1186/s13229-020-00343-4, PubMed 32487215
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Nat Commun, 11 (1), 4016
DOI 10.1038/s41467-020-17376-1, PubMed 32782260
Polygenic scores for schizophrenia and general cognitive ability: associations with six cognitive domains, premorbid intelligence, and cognitive composite score in individuals with a psychotic disorder and in healthy controls
Transl Psychiatry, 10 (1), 416
DOI 10.1038/s41398-020-01094-9, PubMed 33257657
The genetic architecture of the human cerebral cortex
Science, 367 (6484)
DOI 10.1126/science.aay6690, PubMed 32193296
Computationally efficient familywise error rate control in genome-wide association studies using score tests for generalized linear models
Scand. J. Stat., 47 (4), 1090-1113
DOI 10.1111/sjos.12451
Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations
Sci Rep, 10 (1), 9101
DOI 10.1038/s41598-020-65675-w, PubMed 32499510
Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet, 52 (3), 354
DOI 10.1038/s41588-019-0573-x, PubMed 32029921
Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 23 (2), 295
DOI 10.1038/s41593-019-0553-6, PubMed 31848485
Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
Front Psychiatry, 11, 672
DOI 10.3389/fpsyt.2020.00672, PubMed 32754070
The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia
Schizophr Bull, 46 (2), 336-344
DOI 10.1093/schbul/sbz061, PubMed 31206164
Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR
Bioinformatics, 36 (18), 4749-4756
DOI 10.1093/bioinformatics/btaa568, PubMed 32539089
Correction: Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Mol Psychiatry, 25 (4), 914
DOI 10.1038/s41380-019-0456-7, PubMed 31308466
Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci
Biol Psychiatry, 89 (3), 227-235
DOI 10.1016/j.biopsych.2020.01.026, PubMed 32201043
Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
Transl Psychiatry, 10 (1), 198
DOI 10.1038/s41398-020-00888-1, PubMed 32555152
Correction: Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
Transl Psychiatry, 10 (1), 366
DOI 10.1038/s41398-020-01061-4, PubMed 33139722
Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
Front Psychiatry, 11, 642
DOI 10.3389/fpsyt.2020.00642, PubMed 32714224
Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
Mol Psychiatry, 25 (3), 692-695
DOI 10.1038/s41380-019-0358-8, PubMed 30705424
Indicated association between polygenic risk score and treatment-resistance in a naturalistic sample of patients with schizophrenia spectrum disorders
Schizophr Res, 218, 55-62
DOI 10.1016/j.schres.2020.03.006, PubMed 32171635
Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition
JAMA Psychiatry, 77 (4), 420-430
DOI 10.1001/jamapsychiatry.2019.3779, PubMed 31665216
Publications 2019
Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study
Neuropsychopharmacology, 45 (6), 947-955
DOI 10.1038/s41386-019-0556-8, PubMed 31652432
Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk
JAMA Psychiatry, 76 (7), 739-748
DOI 10.1001/jamapsychiatry.2019.0257, PubMed 30969333
Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease
Transl Psychiatry, 9 (1), 273
DOI 10.1038/s41398-019-0592-5, PubMed 31641104
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Nat Commun, 10 (1), 2068
DOI 10.1038/s41467-019-10160-w, PubMed 31043617
Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes
Front Neurosci, 13, 220
DOI 10.3389/fnins.2019.00220, PubMed 30930738
Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
Nat Commun, 10 (1), 2417
DOI 10.1038/s41467-019-10310-0, PubMed 31160569
Identification of common genetic risk variants for autism spectrum disorder
Nat Genet, 51 (3), 431-444
DOI 10.1038/s41588-019-0344-8, PubMed 30804558
Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder
Transl Psychiatry, 9 (1), 258
DOI 10.1038/s41398-019-0599-y, PubMed 31624239
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet, 51 (3), 404-413
DOI 10.1038/s41588-018-0311-9, PubMed 30617256
Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 22 (10), 1617-1623
DOI 10.1038/s41593-019-0471-7, PubMed 31551603
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways
Am J Hum Genet, 105 (2), 334-350
DOI 10.1016/j.ajhg.2019.06.012, PubMed 31374203
GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores
Am J Psychiatry, 176 (8), 651-660
DOI 10.1176/appi.ajp.2019.18080957, PubMed 31164008
Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders
Front Psychiatry, 10, 534
DOI 10.3389/fpsyt.2019.00534, PubMed 31440172
Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations
Cereb Cortex, 29 (2), 875-891
DOI 10.1093/cercor/bhy291, PubMed 30475994
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors
Psychol Med, 49 (10), 1749-1757
DOI 10.1017/S0033291718004142, PubMed 30688187
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors - ERRATUM
Psychol Med, 49 (10), 1758
DOI 10.1017/S0033291719000291, PubMed 30803457
Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder
Mol Psychiatry, 26 (8), 4055-4065
DOI 10.1038/s41380-019-0613-z, PubMed 31792363
Identification of Genetic Loci Shared Between Attention-Deficit/Hyperactivity Disorder, Intelligence, and Educational Attainment
Biol Psychiatry, 87 (12), 1052-1062
DOI 10.1016/j.biopsych.2019.11.015, PubMed 32061372
Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nat Genet, 51 (7), 1193
DOI 10.1038/s41588-019-0450-7, PubMed 31160808
GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
Sci Rep, 9 (1), 7013
DOI 10.1038/s41598-019-43458-2, PubMed 31065058
Author Correction: GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
Sci Rep, 9 (1), 15168
DOI 10.1038/s41598-019-51827-0, PubMed 31619746
GWASinlps: non-local prior based iterative SNP selection tool for genome-wide association studies
Bioinformatics, 35 (1), 1-11
DOI 10.1093/bioinformatics/bty472, PubMed 29931045
Genetic architecture of subcortical brain structures in 38,851 individuals
Nat Genet, 51 (11), 1624-1636
DOI 10.1038/s41588-019-0511-y, PubMed 31636452
Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Mol Psychiatry, 25 (4), 844-853
DOI 10.1038/s41380-018-0332-x, PubMed 30610197
Discovery of shared genomic loci using the conditional false discovery rate approach
Hum Genet, 139 (1), 85-94
DOI 10.1007/s00439-019-02060-2, PubMed 31520123
Genome-wide association study identifies 30 loci associated with bipolar disorder
Nat Genet, 51 (5), 793-803
DOI 10.1038/s41588-019-0397-8, PubMed 31043756
Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders
Psychol Med, 50 (4), 595-606
DOI 10.1017/S0033291719000400, PubMed 30867076
The relationship between physical activity, clinical and cognitive characteristics and BDNF mRNA levels in patients with severe mental disorders
World J Biol Psychiatry, 20 (7), 567-576
DOI 10.1080/15622975.2018.1557345, PubMed 30560709
Telomere length is associated with childhood trauma in patients with severe mental disorders
Transl Psychiatry, 9 (1), 97
DOI 10.1038/s41398-019-0432-7, PubMed 30898995
Publications 2018
Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance
Sci Rep, 8 (1), 12654
DOI 10.1038/s41598-018-30898-5, PubMed 30139959
Vitamin D levels, brain volume, and genetic architecture in patients with psychosis
PLoS One, 13 (8), e0200250
DOI 10.1371/journal.pone.0200250, PubMed 30142216
Cross-tissue eQTL enrichment of associations in schizophrenia
PLoS One, 13 (9), e0202812
DOI 10.1371/journal.pone.0202812, PubMed 30188921
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Nat Commun, 9 (1), 2098
DOI 10.1038/s41467-018-04362-x, PubMed 29844566
An association between YKL-40 and type 2 diabetes in psychotic disorders
Acta Psychiatr Scand, 139 (1), 37-45
DOI 10.1111/acps.12971, PubMed 30328100
Associations between persistent organic pollutants and metabolic syndrome in morbidly obese individuals
Nutr Metab Cardiovasc Dis, 28 (7), 735-742
DOI 10.1016/j.numecd.2018.03.004, PubMed 29699815
Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder
Transl Psychiatry, 8 (1), 55
DOI 10.1038/s41398-018-0102-1, PubMed 29507296
Attenuated Notch signaling in schizophrenia and bipolar disorder
Sci Rep, 8 (1), 5349
DOI 10.1038/s41598-018-23703-w, PubMed 29593239
Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
Transl Psychiatry, 8 (1), 210
DOI 10.1038/s41398-018-0175-x, PubMed 30297702
Stability of the Brain Functional Connectome Fingerprint in Individuals With Schizophrenia
JAMA Psychiatry, 75 (7), 749-751
DOI 10.1001/jamapsychiatry.2018.0844, PubMed 29799905
In Vivo Two-Photon Voltage Imaging with Sulfonated Rhodamine Dyes
ACS Cent Sci, 4 (10), 1371-1378
DOI 10.1021/acscentsci.8b00422, PubMed 30410975
Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)
Twin Res Hum Genet, 21 (5), 394-397
DOI 10.1017/thg.2018.46, PubMed 30001766
A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia
Am J Med Genet B Neuropsychiatr Genet, 177 (4), 454-467
DOI 10.1002/ajmg.b.32634, PubMed 29704319
Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder
Neuropsychopharmacology, 44 (3), 620-628
DOI 10.1038/s41386-018-0273-8, PubMed 30487653
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nat Genet, 50 (3), 381-389
DOI 10.1038/s41588-018-0059-2, PubMed 29483656
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Nat Genet, 50 (7), 912-919
DOI 10.1038/s41588-018-0152-6, PubMed 29942086
Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms
Schizophr Bull, 44 (4), 854-864
DOI 10.1093/schbul/sbx148, PubMed 29136250
Enrichment of genetic markers of recent human evolution in educational and cognitive traits
Sci Rep, 8 (1), 12585
DOI 10.1038/s41598-018-30387-9, PubMed 30135563
Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes
Sci Rep, 8 (1), 6915
DOI 10.1038/s41598-018-25280-4, PubMed 29720671
Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells
Sci Rep, 8 (1), 1765
DOI 10.1038/s41598-018-20173-y, PubMed 29379077
Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
Mol Psychiatry, 25 (3), 584-602
DOI 10.1038/s41380-018-0118-1, PubMed 30283035
Deep 2-photon imaging and artifact-free optogenetics through transparent graphene microelectrode arrays
Nat Commun, 9 (1), 2035
DOI 10.1038/s41467-018-04457-5, PubMed 29789548
Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes
Mol Psychiatry, 25 (11), 3053-3065
DOI 10.1038/s41380-018-0262-7, PubMed 30279459
Meta-analysis of Alzheimer's disease on 9,751 samples from Norway and IGAP study identifies four risk loci
Sci Rep, 8 (1), 18088
DOI 10.1038/s41598-018-36429-6, PubMed 30591712
Identification of shared genetic variants between schizophrenia and lung cancer
Sci Rep, 8 (1), 674
DOI 10.1038/s41598-017-16481-4, PubMed 29330379
Publications 2017
Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure
Sci Rep, 7 (1), 15736
DOI 10.1038/s41598-017-15705-x, PubMed 29147026
Genetic factors influencing prostate cancer risk in Norwegian men
Prostate, 78 (3), 186-192
DOI 10.1002/pros.23453, PubMed 29181843
Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia
Mol Psychiatry, 22 (6), 792-801
DOI 10.1038/mp.2017.33, PubMed 28348379
Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders
Neuroimage Clin, 15, 719-731
DOI 10.1016/j.nicl.2017.06.014, PubMed 28702349
Novel genetic loci associated with hippocampal volume
Nat Commun, 8, 13624
DOI 10.1038/ncomms13624, PubMed 28098162
A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue
Schizophr Bull, 43 (4), 881-890
DOI 10.1093/schbul/sbw183, PubMed 28049760
Parents' Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder-Data from a Norwegian Sample
Int J Mol Sci, 18 (5)
DOI 10.3390/ijms18051078, PubMed 28524073
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets
Cell Rep, 21 (9), 2597-2613
DOI 10.1016/j.celrep.2017.11.028, PubMed 29186694
Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment
Schizophr Bull, 43 (3), 654-664
DOI 10.1093/schbul/sbw085, PubMed 27338279
Genetic risk scores and family history as predictors of schizophrenia in Nordic registers
Psychol Med, 48 (7), 1201-1208
DOI 10.1017/S0033291717002665, PubMed 28942743
Combinations of genetic variants associated with bipolar disorder
PLoS One, 12 (12), e0189739
DOI 10.1371/journal.pone.0189739, PubMed 29267373
Persistent increase in TNF and IL-1 markers in severe mental disorders suggests trait-related inflammation: a one year follow-up study
Acta Psychiatr Scand, 136 (4), 400-408
DOI 10.1111/acps.12783, PubMed 28815548
Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations
NPJ Genom Med, 2, 24
DOI 10.1038/s41525-017-0027-2, PubMed 29263835
Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data
Transl Psychiatry, 7 (12), 1289
DOI 10.1038/s41398-017-0033-2, PubMed 29249828
Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment
J Am Acad Child Adolesc Psychiatry, 57 (2), 86-95
DOI 10.1016/j.jaac.2017.11.013, PubMed 29413154
Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function
JAMA Psychiatry, 74 (10), 1065-1075
DOI 10.1001/jamapsychiatry.2017.1986, PubMed 28746715
Identification of genetic loci shared between schizophrenia and the Big Five personality traits
Sci Rep, 7 (1), 2222
DOI 10.1038/s41598-017-02346-3, PubMed 28533504
Probing the Association between Early Evolutionary Markers and Schizophrenia
PLoS One, 12 (1), e0169227
DOI 10.1371/journal.pone.0169227, PubMed 28081145
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
Mol Psychiatry, 22 (3), 336-345
DOI 10.1038/mp.2016.244, PubMed 28093568
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
Mol Psychiatry, 22 (11), 1651-1652
DOI 10.1038/mp.2017.197, PubMed 29068436
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases
JAMA Neurol, 74 (7), 780-792
DOI 10.1001/jamaneurol.2017.0469, PubMed 28586827
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
Transl Psychiatry, 7 (6), e1155
DOI 10.1038/tp.2017.115, PubMed 28632202
Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not
Psychol Med, 48 (1), 43-49
DOI 10.1017/S0033291717001209, PubMed 28967348
Publications 2016
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Nat Neurosci, 19 (12), 1569-1582
DOI 10.1038/nn.4398, PubMed 27694991
A genetic association study of CSMD1 and CSMD2 with cognitive function
Brain Behav Immun, 61, 209-216
DOI 10.1016/j.bbi.2016.11.026, PubMed 27890662
Modeling psychiatric disorders: from genomic findings to cellular phenotypes
Mol Psychiatry, 21 (9), 1167-79
DOI 10.1038/mp.2016.89, PubMed 27240529
Modeling psychiatric disorders: from genomic findings to cellular phenotypes
Mol Psychiatry, 21 (9), 1321
DOI 10.1038/mp.2016.100, PubMed 27324182
A sequence variant associating with educational attainment also affects childhood cognition
Sci Rep, 6, 36189
DOI 10.1038/srep36189, PubMed 27811963
Contribution of oxytocin receptor polymorphisms to amygdala activation in schizophrenia spectrum disorders
BJPsych Open, 2 (6), 353-358
DOI 10.1192/bjpo.bp.116.003376, PubMed 27847593
Parents' attitudes toward genetic research in autism spectrum disorder
Psychiatr Genet, 26 (2), 74-80
DOI 10.1097/YPG.0000000000000121, PubMed 26867185
Task modulations and clinical manifestations in the brain functional connectome in 1615 fMRI datasets
Neuroimage, 147, 243-252
DOI 10.1016/j.neuroimage.2016.11.073, PubMed 27916665
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Nat Genet, 49 (1), 27-35
DOI 10.1038/ng.3725, PubMed 27869829
Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women
JAMA Psychiatry, 73 (5), 497-505
DOI 10.1001/jamapsychiatry.2016.0129, PubMed 27007234
Functional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study
Biol Psychiatry Cogn Neurosci Neuroimaging, 1 (1), 49-59
DOI 10.1016/j.bpsc.2015.09.002, PubMed 26949748
Inflammatory evidence for the psychosis continuum model
Psychoneuroendocrinology, 67, 189-97
DOI 10.1016/j.psyneuen.2016.02.011, PubMed 26923849
Conservation of Distinct Genetically-Mediated Human Cortical Pattern
PLoS Genet, 12 (7), e1006143
DOI 10.1371/journal.pgen.1006143, PubMed 27459196
The Endogenous Hallucinogen and Trace Amine N,N-Dimethyltryptamine (DMT) Displays Potent Protective Effects against Hypoxia via Sigma-1 Receptor Activation in Human Primary iPSC-Derived Cortical Neurons and Microglia-Like Immune Cells
Front Neurosci, 10, 423
DOI 10.3389/fnins.2016.00423, PubMed 27683542
VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls
Br J Psychiatry, 209 (2), 114-20
DOI 10.1192/bjp.bp.115.161950, PubMed 26941264
The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements
Philos Trans R Soc Lond B Biol Sci, 371 (1705)
DOI 10.1098/rstb.2015.0356, PubMed 27574309
Cell type specificity of neurovascular coupling in cerebral cortex
Elife, 5
DOI 10.7554/eLife.14315, PubMed 27244241
Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors
Mult Scler, 22 (14), 1783-1793
DOI 10.1177/1352458516635873, PubMed 26920376
Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS
PLoS Genet, 12 (1), e1005803
DOI 10.1371/journal.pgen.1005803, PubMed 26808560
Pleiotropic Analysis of Lung Cancer and Blood Triglycerides
J Natl Cancer Inst, 108 (12)
DOI 10.1093/jnci/djw167, PubMed 27565901
Publications 2015
Polygenic risk scores in bipolar disorder subgroups
J Affect Disord, 183, 310-4
DOI 10.1016/j.jad.2015.05.021, PubMed 26047958
Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
PLoS One, 10 (4), e0123057
DOI 10.1371/journal.pone.0123057, PubMed 25853426
Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms
PLoS One, 10 (5), e0128048
DOI 10.1371/journal.pone.0128048, PubMed 25978331
Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
PLoS Genet, 11 (11), e1005544
DOI 10.1371/journal.pgen.1005544, PubMed 26540268
Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs
J Psychopharmacol, 29 (8), 884-91
DOI 10.1177/0269881115584469, PubMed 25944848
Large-scale genomics unveil polygenic architecture of human cortical surface area
Nat Commun, 6, 7549
DOI 10.1038/ncomms8549, PubMed 26189703
Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease
Circulation, 131 (23), 2061-2069
DOI 10.1161/CIRCULATIONAHA.115.015489, PubMed 25862742
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus
Mol Psychiatry, 20 (12), 1588-95
DOI 10.1038/mp.2015.6, PubMed 25687773
MicroRNAs enrichment in GWAS of complex human phenotypes
BMC Genomics, 16 (1), 304
DOI 10.1186/s12864-015-1513-5, PubMed 25884492
Association between Genetic Variation in the Oxytocin Receptor Gene and Emotional Withdrawal, but not between Oxytocin Pathway Genes and Diagnosis in Psychotic Disorders
Front Hum Neurosci, 9, 9
DOI 10.3389/fnhum.2015.00009, PubMed 25667571
Common genetic variants influence human subcortical brain structures
Nature, 520 (7546), 224-9
DOI 10.1038/nature14101, PubMed 25607358
Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders
Nord J Psychiatry, 70 (4), 276-9
DOI 10.3109/08039488.2015.1095944, PubMed 26559242
Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls
Schizophr Res, 165 (2-3), 188-94
DOI 10.1016/j.schres.2015.04.004, PubMed 25956633
Genome-wide autozygosity is associated with lower general cognitive ability
Mol Psychiatry, 21 (6), 837-43
DOI 10.1038/mp.2015.120, PubMed 26390830
A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia
Biol Psychiatry, 80 (4), 323-330
DOI 10.1016/j.biopsych.2015.09.021, PubMed 26682468
Microarray Analysis of Copy Number Variants on the Human Y Chromosome Reveals Novel and Frequent Duplications Overrepresented in Specific Haplogroups
PLoS One, 10 (8), e0137223
DOI 10.1371/journal.pone.0137223, PubMed 26322892
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors
Circ Res, 118 (1), 83-94
DOI 10.1161/CIRCRESAHA.115.306629, PubMed 26487741
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis
Int J Epidemiol, 44 (5), 1706-21
DOI 10.1093/ije/dyv136, PubMed 26286434
Combinations of Genetic Data Present in Bipolar Patients, but Absent in Control Persons
PLoS One, 10 (11), e0143432
DOI 10.1371/journal.pone.0143432, PubMed 26587987
Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci
PLoS One, 10 (12), e0144531
DOI 10.1371/journal.pone.0144531, PubMed 26695485
Genetic Markers of Human Evolution Are Enriched in Schizophrenia
Biol Psychiatry, 80 (4), 284-292
DOI 10.1016/j.biopsych.2015.10.009, PubMed 26681495
Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease
Nat Genet, 47 (5), 445-7
DOI 10.1038/ng.3246, PubMed 25807283
Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder
PLoS One, 10 (7), e0134202
DOI 10.1371/journal.pone.0134202, PubMed 26222050
Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment
Am J Med Genet B Neuropsychiatr Genet, 168B (5), 363-73
DOI 10.1002/ajmg.b.32319, PubMed 25951819
Genome-wide analysis of attention deficit hyperactivity disorder in Norway
PLoS One, 10 (4), e0122501
DOI 10.1371/journal.pone.0122501, PubMed 25875332
Publications 2014
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci
Mol Psychiatry, 20 (2), 207-14
DOI 10.1038/mp.2013.195, PubMed 24468824
Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes
Hypertension, 63 (4), 819-26
DOI 10.1161/HYPERTENSIONAHA.113.02077, PubMed 24396023
Shared common variants in prostate cancer and blood lipids
Int J Epidemiol, 43 (4), 1205-14
DOI 10.1093/ije/dyu090, PubMed 24786909
GWAS-based pathway analysis differentiates between fluid and crystallized intelligence
Genes Brain Behav, 13 (7), 663-74
DOI 10.1111/gbb.12152, PubMed 24975275
Association between altered brain morphology and elevated peripheral endothelial markers--implications for psychotic disorders
Schizophr Res, 161 (2-3), 222-8
DOI 10.1016/j.schres.2014.11.006, PubMed 25433965
An attempt to identify single nucleotide polymorphisms contributing to possible relationships between personality traits and oxytocin-related genes
Neuropsychobiology, 69 (1), 25-30
DOI 10.1159/000356965, PubMed 24458227
Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls
Schizophr Bull, 41 (3), 736-43
DOI 10.1093/schbul/sbu152, PubMed 25392519
Polygenic risk score and the psychosis continuum model
Acta Psychiatr Scand, 130 (4), 311-7
DOI 10.1111/acps.12307, PubMed 24961959
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Brain Imaging Behav, 8 (2), 153-82
DOI 10.1007/s11682-013-9269-5, PubMed 24399358
ANK3 gene expression in bipolar disorder and schizophrenia
Br J Psychiatry, 205 (3), 244-5
DOI 10.1192/bjp.bp.114.145433, PubMed 24809399
Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders
World J Biol Psychiatry, 16 (3), 171-9
DOI 10.3109/15622975.2014.953011, PubMed 25264289
Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders
J Psychiatr Res, 59, 14-21
DOI 10.1016/j.jpsychires.2014.08.011, PubMed 25246365
Publications 2013
A comprehensive family-based replication study of schizophrenia genes
JAMA Psychiatry, 70 (6), 573-81
DOI 10.1001/jamapsychiatry.2013.288, PubMed 23894747
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors
Am J Hum Genet, 92 (2), 197-209
DOI 10.1016/j.ajhg.2013.01.001, PubMed 23375658
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate
PLoS Genet, 9 (4), e1003455
DOI 10.1371/journal.pgen.1003455, PubMed 23637625
ZNF804A and cortical thickness in schizophrenia and bipolar disorder
Psychiatry Res, 212 (2), 154-7
DOI 10.1016/j.pscychresns.2013.01.007, PubMed 23562677
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Nat Genet, 45 (9), 984-94
DOI 10.1038/ng.2711, PubMed 23933821
A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder
PLoS One, 8 (12), e81052
DOI 10.1371/journal.pone.0081052, PubMed 24349030
Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia
J Affect Disord, 163, 110-4
DOI 10.1016/j.jad.2013.12.018, PubMed 24461634
Genetic clustering on the hippocampal surface for genome-wide association studies
Med Image Comput Comput Assist Interv, 16 (Pt 2), 690-7
DOI 10.1007/978-3-642-40763-5_85, PubMed 24579201
Genetic Clustering on the Hippocampal Surface for Genome-Wide Association Studies
LECT NOTES COMPUT SC, 8150, 690-697
Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)
Mol Psychiatry, 19 (2), 168-74
DOI 10.1038/mp.2013.166, PubMed 24342994
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia
Mol Psychiatry, 19 (9), 1017-1024
DOI 10.1038/mp.2013.138, PubMed 24280982
No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes
J Affect Disord, 151 (1), 291-7
DOI 10.1016/j.jad.2013.06.008, PubMed 23820096
CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls
PLoS One, 8 (2), e56970
DOI 10.1371/journal.pone.0056970, PubMed 23437284
BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses
Prog Neuropsychopharmacol Biol Psychiatry, 46, 181-8
DOI 10.1016/j.pnpbp.2013.07.008, PubMed 23876786
Publications 2012
Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study
Psychiatry Res, 197 (3), 327-36
DOI 10.1016/j.psychres.2011.12.036, PubMed 22417934
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans
Proc Natl Acad Sci U S A, 109 (10), 3985-90
DOI 10.1073/pnas.1105829109, PubMed 22343285
Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach
Transl Psychiatry, 2 (7), e143
DOI 10.1038/tp.2012.67, PubMed 22828495
Linkage-disequilibrium-based binning affects the interpretation of GWASs
Am J Hum Genet, 90 (4), 727-33
DOI 10.1016/j.ajhg.2012.02.025, PubMed 22444669
Up-regulation of NOTCH4 gene expression in bipolar disorder
Am J Psychiatry, 169 (12), 1292-300
DOI 10.1176/appi.ajp.2012.11091431, PubMed 23212060
Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders
PLoS One, 7 (2), e31687
DOI 10.1371/journal.pone.0031687, PubMed 22384057
DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder
PLoS One, 7 (4), e35424
DOI 10.1371/journal.pone.0035424, PubMed 22539971
Variant of TREM2 associated with the risk of Alzheimer's disease
N Engl J Med, 368 (2), 107-16
DOI 10.1056/NEJMoa1211103, PubMed 23150908
Lack of association between the regulator of G-protein signaling 4 (RGS4) rs951436 polymorphism and schizophrenia
Psychiatr Genet, 22 (5), 263-4
DOI 10.1097/YPG.0b013e32834f3558, PubMed 22157635
Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis
Am J Med Genet B Neuropsychiatr Genet, 159B (6), 722-30
DOI 10.1002/ajmg.b.32076, PubMed 22815203
Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
Behav Brain Funct, 8, 24
DOI 10.1186/1744-9081-8-24, PubMed 22594806
Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways
Neuroimage, 70, 143-9
DOI 10.1016/j.neuroimage.2012.12.035, PubMed 23274185
Connection between genetic and clinical data in bipolar disorder
PLoS One, 7 (9), e44623
DOI 10.1371/journal.pone.0044623, PubMed 23028568
Associations between variants near a monoaminergic pathways gene (PHOX2B) and amygdala reactivity: a genome-wide functional imaging study
Twin Res Hum Genet, 15 (3), 273-85
DOI 10.1017/thg.2012.5, PubMed 22856363
Identification of common variants associated with human hippocampal and intracranial volumes
Nat Genet, 44 (5), 552-61
DOI 10.1038/ng.2250, PubMed 22504417
Common variant at 16p11.2 conferring risk of psychosis
Mol Psychiatry, 19 (1), 108-14
DOI 10.1038/mp.2012.157, PubMed 23164818
Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder
Biol Psychiatry, 72 (8), 645-50
DOI 10.1016/j.biopsych.2012.02.040, PubMed 22560537
TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders
Transl Psychiatry, 2 (5), e112
DOI 10.1038/tp.2012.39, PubMed 22832956
Publications 2011
Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia
Biol Psychiatry, 70 (7), 696-8
DOI 10.1016/j.biopsych.2011.02.034, PubMed 21514568
Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia
Arch Gen Psychiatry, 68 (8), 781-90
DOI 10.1001/archgenpsychiatry.2011.81, PubMed 21810643
Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia
Psychiatr Genet, 21 (4), 214-5
DOI 10.1097/YPG.0b013e328341e020, PubMed 21712758
Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder (vol 88, pg 372, 2011)
Am. J. Hum. Genet., 88 (3), 396
DOI 10.1016/j.ajhg.2011.03.001
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder
Am J Hum Genet, 88 (3), 372-81
DOI 10.1016/j.ajhg.2011.01.017, PubMed 21353194
Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway
PLoS One, 6 (12), e28302
DOI 10.1371/journal.pone.0028302, PubMed 22164265
At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia
Biol Psychiatry, 70 (1), 59-63
DOI 10.1016/j.biopsych.2011.01.031, PubMed 21414605
The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia
Biol Psychiatry, 70 (1), 35-42
DOI 10.1016/j.biopsych.2011.01.030, PubMed 21439553
Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness
Am J Psychiatry, 168 (4), 408-17
DOI 10.1176/appi.ajp.2010.09111660, PubMed 21324950
Combinations of SNPs related to signal transduction in bipolar disorder
PLoS One, 6 (8), e23812
DOI 10.1371/journal.pone.0023812, PubMed 21897858
Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function
J Psychiatr Res, 46 (2), 271-8
DOI 10.1016/j.jpsychires.2011.11.001, PubMed 22126837
Copy number variations in affective disorders and meta-analysis
Psychiatr Genet, 21 (6), 319-22
DOI 10.1097/YPG.0b013e3283463deb, PubMed 21451435
Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes
Genet Epidemiol, 35 (5), 318-32
DOI 10.1002/gepi.20580, PubMed 21484861
Common variants at VRK2 and TCF4 conferring risk of schizophrenia
Hum Mol Genet, 20 (20), 4076-81
DOI 10.1093/hmg/ddr325, PubMed 21791550
Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples
Am J Med Genet B Neuropsychiatr Genet, 156B (8), 969-74
DOI 10.1002/ajmg.b.31244, PubMed 21972176
Dual association of a TRKA polymorphism with schizophrenia
Psychiatr Genet, 21 (3), 125-31
DOI 10.1097/YPG.0b013e3283437194, PubMed 21317683
Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders
Schizophr Bull, 38 (1), 15-22
DOI 10.1093/schbul/sbr113, PubMed 21908796
Publications 2010
Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
J Psychiatr Res, 44 (12), 748-53
DOI 10.1016/j.jpsychires.2010.02.002, PubMed 20185149
Intron 12 in NTRK3 is associated with bipolar disorder
Psychiatry Res, 185 (3), 358-62
DOI 10.1016/j.psychres.2010.05.011, PubMed 20554328
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia
Mol Psychiatry, 16 (11), 1117-29
DOI 10.1038/mp.2010.96, PubMed 20838396
A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
J Affect Disord, 126 (1-2), 312-6
DOI 10.1016/j.jad.2010.04.007, PubMed 20451256
Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: an association study
Schizophr Res, 127 (1-3), 270-2
DOI 10.1016/j.schres.2010.10.002, PubMed 21030213
Osteoprotegerin levels in patients with severe mental disorders
J Psychiatry Neurosci, 35 (5), 304-10
DOI 10.1503/jpn.090088, PubMed 20569643
A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia
Hum Mol Genet, 19 (7), 1379-86
DOI 10.1093/hmg/ddq009, PubMed 20071346
Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area
Biol Psychiatry, 69 (1), 90-6
DOI 10.1016/j.biopsych.2010.07.035, PubMed 20950796
Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples
Am J Med Genet B Neuropsychiatr Genet, 153B (1), 86-96
DOI 10.1002/ajmg.b.30958, PubMed 19350560
The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
Am J Med Genet B Neuropsychiatr Genet, 153B (2), 387-396
DOI 10.1002/ajmg.b.30991, PubMed 19526457
SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders
Prog Neuropsychopharmacol Biol Psychiatry, 34 (8), 1500-6
DOI 10.1016/j.pnpbp.2010.08.013, PubMed 20800085
Expanding the range of ZNF804A variants conferring risk of psychosis
Mol Psychiatry, 16 (1), 59-66
DOI 10.1038/mp.2009.149, PubMed 20048749
Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample
Am J Med Genet B Neuropsychiatr Genet, 153B (7), 1276-82
DOI 10.1002/ajmg.b.31098, PubMed 20872766
Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
Am J Med Genet B Neuropsychiatr Genet, 153B (2), 610-618
DOI 10.1002/ajmg.b.31030, PubMed 19746410
Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls
Schizophr Res, 122 (1-3), 31-7
DOI 10.1016/j.schres.2010.05.007, PubMed 20605701
Publications 2009
Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia
Psychiatr Genet, 19 (5), 273-4
DOI 10.1097/YPG.0b013e32832a4fcd, PubMed 19491717
Measurements of Hbeta Stark central asymmetry and its analysis through standard theory and computer simulations
Phys Rev E Stat Nonlin Soft Matter Phys, 79 (4 Pt 2), 046402
DOI 10.1103/PhysRevE.79.046402, PubMed 19518354
Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
Psychiatry Res, 168 (3), 256-8
DOI 10.1016/j.psychres.2008.08.007, PubMed 19223264
Copy number variations of chromosome 16p13.1 region associated with schizophrenia
Mol Psychiatry, 16 (1), 17-25
DOI 10.1038/mp.2009.101, PubMed 19786961
A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations
Proc Natl Acad Sci U S A, 106 (36), 15483-8
DOI 10.1073/pnas.0901866106, PubMed 19717458
DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
Neuropsychobiology, 59 (3), 142-50
DOI 10.1159/000218076, PubMed 19439994
Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia
Neurobiol Dis, 34 (3), 518-24
DOI 10.1016/j.nbd.2009.03.011, PubMed 19344762
Sex-dependent association of common variants of microcephaly genes with brain structure
Proc Natl Acad Sci U S A, 107 (1), 384-8
DOI 10.1073/pnas.0908454107, PubMed 20080800
Common variants conferring risk of schizophrenia
Nature, 460 (7256), 744-7
DOI 10.1038/nature08186, PubMed 19571808
No association between DGKH and bipolar disorder in a Scandinavian case-control sample
Psychiatr Genet, 19 (5), 269-72
DOI 10.1097/YPG.0b013e32832d302f, PubMed 19478689
Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia
J Psychiatr Res, 43 (15), 1195-9
DOI 10.1016/j.jpsychires.2009.04.006, PubMed 19435634
Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
Neuropsychobiology, 60 (1), 31-6
DOI 10.1159/000235799, PubMed 19729970
Publications 2008
A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE)
Schizophr Res, 107 (2-3), 242-8
DOI 10.1016/j.schres.2008.10.010, PubMed 19022628
Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
Am J Med Genet B Neuropsychiatr Genet, 147B (6), 976-82
DOI 10.1002/ajmg.b.30671, PubMed 18165967
Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
Am J Med Genet B Neuropsychiatr Genet, 147B (7), 1089-100
DOI 10.1002/ajmg.b.30726, PubMed 18384059
Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples
Mol Psychiatry, 15 (5), 463-72
DOI 10.1038/mp.2008.110, PubMed 18936756
The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
BMC Med Genet, 9, 39
DOI 10.1186/1471-2350-9-39, PubMed 18460190
Disruption of the neurexin 1 gene is associated with schizophrenia
Hum Mol Genet, 18 (5), 988-96
DOI 10.1093/hmg/ddn351, PubMed 18945720
Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample
Schizophr Res, 106 (2-3), 237-41
DOI 10.1016/j.schres.2008.08.024, PubMed 18818052
Large recurrent microdeletions associated with schizophrenia
Nature, 455 (7210), 232-6
DOI 10.1038/nature07229, PubMed 18668039
Publications 2007
The effect of red wine on plasma leptin levels and vasoactive factors from adipose tissue: a randomized crossover trial
Alcohol Alcohol, 42 (6), 525-8
DOI 10.1093/alcalc/agm056, PubMed 17670801
Brain expressed microRNAs implicated in schizophrenia etiology
PLoS One, 2 (9), e873
DOI 10.1371/journal.pone.0000873, PubMed 17849003
A novel myogenic cell line with phenotypic properties of muscle progenitors
J Mol Med (Berl), 86 (1), 105-15
DOI 10.1007/s00109-007-0268-0, PubMed 17957349
Publications 2006
Influence of different lipoprotein lipase gene polymorphisms on developing pancreatitis of different etiology in Croatian patients
Period. Biol., 108 (5), 581-586
Publications 2005
Asymmetry of Hbeta Stark profiles in T-tube hydrogen plasma
Phys Rev E Stat Nonlin Soft Matter Phys, 71 (3 Pt 2B), 036407
DOI 10.1103/PhysRevE.71.036407, PubMed 15903588
Activity of peroxisomal enzymes, and levels of polyamines in LPA-transgenic mice on two different diets
Lipids Health Dis, 4, 23
DOI 10.1186/1476-511X-4-23, PubMed 16202171
Electroporation by nucleofector is the best nonviral transfection technique in human endothelial and smooth muscle cells
Genet Vaccines Ther, 3 (1), 2
DOI 10.1186/1479-0556-3-2, PubMed 15836781
Lack of association between low HDL-cholesterol and elevated circulating cellular adhesion molecules in normolipidemic CAD patients and healthy subjects
Int Heart J, 46 (4), 593-600
DOI 10.1536/ihj.46.593, PubMed 16157950
Daily administration of interleukin-18 causes myocardial dysfunction in healthy mice
Am J Physiol Heart Circ Physiol, 289 (2), H708-14
DOI 10.1152/ajpheart.01179.2004, PubMed 15821032
Publications 2004
Comparison of nonviral transfection and adeno-associated viral transduction on cardiomyocytes
Mol Biotechnol, 28 (1), 21-32
DOI 10.1385/MB:28:1:21, PubMed 15456960
Variations in transfection efficiency of VEGF165 and VEGF121-cDNA: its effects on proliferation and migration of human endothelial cells
Mol Biotechnol, 26 (1), 7-16
DOI 10.1385/MB:26:1:7, PubMed 14734819
Missense mutation W86R in exon 3 of the lipoprotein lipase gene in a boy with chylomicronemia
Clin Chim Acta, 343 (1-2), 179-84
DOI 10.1016/j.cccn.2004.01.029, PubMed 15115692
Human apoB contributes to increased serum total apo(a) level in LPA transgenic mice
Lipids Health Dis, 3, 8
DOI 10.1186/1476-511X-3-8, PubMed 15134578
Publications 2003
Circulating transforming growth factor-beta1, lipoprotein(a) and cellular adhesion molecules in angiographically assessed coronary artery disease
Clin Chem Lab Med, 41 (7), 893-8
DOI 10.1515/CCLM.2003.135, PubMed 12940514
Comment on "Atomic spectral line-free parameter deconvolution procedure"
Phys Rev E Stat Nonlin Soft Matter Phys, 67 (5 Pt 2), 058401; author reply 058402
DOI 10.1103/PhysRevE.67.058401, PubMed 12786332
Smoking and relation to other risk factors in postmenopausal women with coronary artery disease, with particular reference to whole blood viscosity and beta-cell function
J Intern Med, 253 (2), 232-9
DOI 10.1046/j.1365-2796.2003.01110.x, PubMed 12542565
Smoking and relation to other risk factors in postmenopausal women with coronary artery disease, with particular reference to whole blood viscosity and beta-cell function
In Journal of internal medicine, Blackwell Scientific Publ., Oxford, 253(2003)2, s.232-9
BIBSYS 041722221
Publications 2002
Spontaneous atherosclerosis in the proximal aorta of LPA transgenic mice on a normal diet
Atherosclerosis, 163 (1), 99-104
DOI 10.1016/s0021-9150(01)00772-9, PubMed 12048126
Altered plasma concentrations of leptin, transforming growth factor-beta(1) and plasminogen activator inhibitor type 2 at 18 weeks of gestation in women destined to develop pre-eclampsia. Circulating markers of disturbed placentation?
Placenta, 23 (5), 380-5
DOI 10.1053/plac.2002.0828, PubMed 12061853
Absence of enhanced systemic inflammatory response at 18 weeks of gestation in women with subsequent pre-eclampsia
BJOG, 109 (7), 759-64
DOI 10.1111/j.1471-0528.2002.01330.x, PubMed 12135211
Transforming growth factor (TGF)-beta1 inversely related to vascular cell adhesion molecule-1 in postmenopausal women with coronary artery disease. A possible mechanism for the putative cardioprotective role of TGF-beta1?
J Intern Med, 251 (3), 223-7
DOI 10.1046/j.1365-2796.2002.00950.x, PubMed 11886481
Hormone replacement therapy does not affect plasma homocysteine in postmenopausal women with coronary artery disease. Free tissue factor pathway inhibitor antigen, a circulating anticoagulant, is related to plasma homocysteine
Cardiology, 98 (1-2), 6-12
DOI 10.1159/000064667, PubMed 12373040
Publications 2001
Dyslipidemia in early second trimester is mainly a feature of women with early onset pre-eclampsia
BJOG, 108 (10), 1081-7
DOI 10.1111/j.1471-0528.2001.00247.x, PubMed 11702841
Plasma N-terminal pro-atrial natriuretic peptide predicts death after premature myocardial infarction, but not as well as radionuclide ejection fraction. A ten-year follow-up study
Scand Cardiovasc J, 35 (6), 373-8
DOI 10.1080/14017430152754853, PubMed 11837516
Publications 2000
Gene encoding the apo(a) protein in LPA
Atherosclerosis, 148 (1), 203
DOI 10.1016/s0021-9150(99)00348-2, PubMed 10644289
Altered circulating levels of adhesion molecules at 18 weeks' gestation among women with eventual preeclampsia: indicators of disturbed placentation in absence of evidence of endothelial dysfunction?
Am J Obstet Gynecol, 182 (2), 321-5
DOI 10.1016/s0002-9378(00)70218-3, PubMed 10694331
Increased plasma concentrations of TGF-beta1 after hormone replacement therapy
J Intern Med, 247 (2), 279-85
DOI 10.1046/j.1365-2796.2000.00648.x, PubMed 10692092
Histopathology of arterial lesions in LPA transgenic mice on cholesterol-enriched chow
Atherosclerosis, 153 (2), 349-54
DOI 10.1016/s0021-9150(00)00430-5, PubMed 11164423
Publications 1999
Whole blood folate, homocysteine in serum, and risk of first acute myocardial infarction
Atherosclerosis, 147 (2), 317-26
DOI 10.1016/s0021-9150(99)00202-6, PubMed 10559518
Altered serum concentrations of TGF-beta 1 and Lp(a) lipoprotein and their correlation in patients with first acute myocardial infarction
Nutr Metab Cardiovasc Dis, 9 (5), 250-4
PubMed 10656172
Publications 1997
Studies on effects of Lp(a) lipoprotein on gene expression in endothelial cells in vitro
Clin Genet, 52 (5), 314-25
DOI 10.1111/j.1399-0004.1997.tb04349.x, PubMed 9520122
Epidemiology of Lp(a) lipoprotein: its role in atherosclerotic/thrombotic disease
Clin Genet, 52 (5), 281-92
DOI 10.1111/j.1399-0004.1997.tb04345.x, PubMed 9520118
Increased levels of intercellular adhesion molecules and vascular cell adhesion molecules in pre-eclampsia
Br J Obstet Gynaecol, 104 (4), 466-70
DOI 10.1111/j.1471-0528.1997.tb11499.x, PubMed 9141584
Plasma concentrations of Lp(a) lipoprotein and TGF-beta1 are altered in preeclampsia
Clin Genet, 52 (5), 371-6
DOI 10.1111/j.1399-0004.1997.tb04356.x, PubMed 9520129
Publications 1996
Oscillator strengths for N
Phys Rev A, 53 (5), 3122-3128
DOI 10.1103/physreva.53.3122, PubMed 9913252
Publications 1995
Search for ion dynamics effects on the shift and width of plasma-broadened C I and O I spectral lines
Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics, 51 (1), 613-618
DOI 10.1103/physreve.51.613, PubMed 9962682
Publications 1993
Absolute Spatially- and Temporally-Resolved Optical Emission Measurements of rf Glow Discharges in Argon
J Res Natl Inst Stand Technol, 98 (2), 159-180
DOI 10.6028/jres.098.012, PubMed 28053464
Publications 1991
Shifts of the H beta line in dense hydrogen plasmas
Phys Rev A, 43 (11), 6095-6097
DOI 10.1103/physreva.43.6095, PubMed 9904942