Publications 2024
The effect of polygenic risk score and childhood adversity on transdiagnostic symptom dimensions at first-episode psychosis: evidence for an affective pathway to psychosis
Transl Psychiatry, 14 (1), 454
DOI 10.1038/s41398-024-03149-7, PubMed 39461938
Telomere biology and its maintenance in schizophrenia spectrum disorders: Exploring links to cognition
Schizophr Res, 272, 89-95
DOI 10.1016/j.schres.2024.08.011, PubMed 39208769
Publications 2023
Exploring the mediation of DNA methylation across the epigenome between childhood adversity and First Episode of Psychosis-findings from the EU-GEI study
Mol Psychiatry, 28 (5), 2095-2106
DOI 10.1038/s41380-023-02044-9, PubMed 37062770
Association Between Childhood Adversity and Functional Outcomes in People With Psychosis: A Meta-analysis
Schizophr Bull, 49 (2), 285-296
DOI 10.1093/schbul/sbac105, PubMed 36107860
Tobacco smoking related to childhood trauma mediated by cognitive control and impulsiveness in severe mental disorders
Schizophr Res, 261, 236-244
DOI 10.1016/j.schres.2023.09.041, PubMed 37806047
Telomere length and verbal learning in bipolar disorders
J Affect Disord, 339, 555-560
DOI 10.1016/j.jad.2023.07.087, PubMed 37459977
Polygenic risk for schizophrenia and bipolar disorder in relation to cardiovascular biomarkers
Eur Arch Psychiatry Clin Neurosci, 274 (5), 1223-1230
DOI 10.1007/s00406-023-01591-0, PubMed 37145175
The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case-control study
Soc Psychiatry Psychiatr Epidemiol, 58 (10), 1573-1580
DOI 10.1007/s00127-023-02513-0, PubMed 37335320
Cannabis use as a potential mediator between childhood adversity and first-episode psychosis: results from the EU-GEI case-control study
Psychol Med, 53 (15), 7375-7384
DOI 10.1017/S0033291723000995, PubMed 38078747
Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders
Sci Rep, 13 (1), 13845
DOI 10.1038/s41598-023-40310-6, PubMed 37620394
The role of interpersonal trauma and substance use in mental health: A large population-based study
Psychiatry Res, 333, 115712
DOI 10.1016/j.psychres.2023.115712, PubMed 38219350
Publications 2022
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J. Affect. Disord., 297, 1032-1039
DOI 10.1016/j.jad.2021.08.135
An epigenetic association analysis of childhood trauma in psychosis reveals possible overlap with methylation changes associated with PTSD
Transl Psychiatry, 12 (1), 177
DOI 10.1038/s41398-022-01936-8, PubMed 35501310
Childhood Maltreatment, Educational Attainment, and IQ: Findings From a Multicentric Case-control Study of First-episode Psychosis (EU-GEI)
Schizophr Bull, 48 (3), 575-589
DOI 10.1093/schbul/sbac004, PubMed 35137235
Retrospectively assessed childhood trauma experiences are associated with illness severity in mental disorders adjusted for symptom state
Psychiatry Res, 320, 115045
DOI 10.1016/j.psychres.2022.115045, PubMed 36621206
Publications 2021
Association Between Specific Childhood Adversities and Symptom Dimensions in People With Psychosis: Systematic Review and Meta-Analysis
Schizophr Bull, 47 (4), 975-985
DOI 10.1093/schbul/sbaa199, PubMed 33836526
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J Affect Disord, 295, 1032-1039
DOI 10.1016/j.jad.2021.08.135, PubMed 34706411
Childhood Maltreatment in Bipolar Disorders
Curr Top Behav Neurosci, 48, 277-301
DOI 10.1007/7854_2020_149, PubMed 32653999
Childhood trauma and cardiometabolic risk in severe mental disorders: The mediating role of cognitive control
Eur Psychiatry, 64 (1), e24
DOI 10.1192/j.eurpsy.2021.14, PubMed 33775258
Exploring the Interplay Between Adversity, Neurocognition, Social Cognition, and Functional Outcome in People With Psychosis: A Narrative Review
Front Psychiatry, 12, 596949
DOI 10.3389/fpsyt.2021.596949, PubMed 33762975
Synergistic effects of childhood adversity and polygenic risk in first-episode psychosis: the EU-GEI study
Psychol Med, 53 (5), 1970-1978
DOI 10.1017/S0033291721003664, PubMed 37310339
Physical activity and childhood trauma experiences in patients with schizophrenia or bipolar disorders
World J Biol Psychiatry, 22 (8), 637-645
DOI 10.1080/15622975.2021.1907707, PubMed 33779484
Publications 2020
A systematic review on mediators between adversity and psychosis: potential targets for treatment
Psychol Med, 50 (12), 1966-1976
DOI 10.1017/S0033291720002421, PubMed 32744193
Childhood trauma is associated with poorer social functioning in severe mental disorders both during an active illness phase and in remission
Schizophr Res, 243, 241-246
DOI 10.1016/j.schres.2020.03.015, PubMed 32222348
Sleep disturbance mediates the link between childhood trauma and clinical outcome in severe mental disorders
Psychol Med, 51 (14), 2337-2346
DOI 10.1017/S0033291720000914, PubMed 32321600
Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
Front Psychiatry, 11, 672
DOI 10.3389/fpsyt.2020.00672, PubMed 32754070
Sexual abuse and physical neglect in childhood are associated with affective theory of mind in adults with schizophrenia
Schizophr Res Cogn, 23, 100189
DOI 10.1016/j.scog.2020.100189, PubMed 33134093
Childhood Trauma Is Nominally Associated With Elevated Cortisol Metabolism in Severe Mental Disorder
Front Psychiatry, 11, 391
DOI 10.3389/fpsyt.2020.00391, PubMed 32528319
Publications 2019
The Ring of Fire: Childhood Trauma, Emotional Reactivity, and Mixed States in Mood Disorders
Psychiatr Clin North Am, 43 (1), 69-82
DOI 10.1016/j.psc.2019.10.007, PubMed 32008689
Do sleep disturbances contribute to cognitive impairments in schizophrenia spectrum and bipolar disorders?
Eur Arch Psychiatry Clin Neurosci, 270 (6), 749-759
DOI 10.1007/s00406-019-01075-0, PubMed 31587109
Sleep disturbances in schizophrenia spectrum and bipolar disorders - a transdiagnostic perspective
Compr Psychiatry, 91, 6-12
DOI 10.1016/j.comppsych.2019.02.006, PubMed 30856497
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors
Psychol Med, 49 (10), 1749-1757
DOI 10.1017/S0033291718004142, PubMed 30688187
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors - ERRATUM
Psychol Med, 49 (10), 1758
DOI 10.1017/S0033291719000291, PubMed 30803457
Childhood maltreatment and polygenic risk in bipolar disorders
Bipolar Disord, 22 (2), 174-181
DOI 10.1111/bdi.12851, PubMed 31628696
The relationship between physical activity, clinical and cognitive characteristics and BDNF mRNA levels in patients with severe mental disorders
World J Biol Psychiatry, 20 (7), 567-576
DOI 10.1080/15622975.2018.1557345, PubMed 30560709
Telomere length is associated with childhood trauma in patients with severe mental disorders
Transl Psychiatry, 9 (1), 97
DOI 10.1038/s41398-019-0432-7, PubMed 30898995
Elevated hair cortisol is associated with childhood maltreatment and cognitive impairment in schizophrenia and in bipolar disorders
Schizophr Res, 213, 65-71
DOI 10.1016/j.schres.2019.01.011, PubMed 30660575
Biological stress response in women at risk of postpartum psychosis: The role of life events and inflammation
Psychoneuroendocrinology, 113, 104558
DOI 10.1016/j.psyneuen.2019.104558, PubMed 31923613
Publications 2018
Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders
Schizophr Res, 205, 45-50
DOI 10.1016/j.schres.2018.08.007, PubMed 30126813
Publications 2017
Childhood Trauma and Minimization/Denial in People with and without a Severe Mental Disorder
Front Psychol, 8, 1276
DOI 10.3389/fpsyg.2017.01276, PubMed 28883800
Response to Xuerong Luo et al., Letter to the Editor
Brain Behav Immun, 65, 363
DOI 10.1016/j.bbi.2017.07.006, PubMed 28698114
Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses
Brain Behav Immun, 65, 342-349
DOI 10.1016/j.bbi.2017.06.005, PubMed 28619247
Publications 2016
Alcohol use disorders are associated with increased affective lability in bipolar disorder
J Affect Disord, 208, 316-324
DOI 10.1016/j.jad.2016.09.062, PubMed 27810713
Inflammatory evidence for the psychosis continuum model
Psychoneuroendocrinology, 67, 189-97
DOI 10.1016/j.psyneuen.2016.02.011, PubMed 26923849
The neural diathesis-stress model of schizophrenia revisited: An update on recent findings considering illness stage and neurobiological and methodological complexities
Neurosci Biobehav Rev, 73, 191-218
DOI 10.1016/j.neubiorev.2016.12.013, PubMed 27993603
Serum levels of second-generation antipsychotics are associated with cognitive function in psychotic disorders
World J Biol Psychiatry, 18 (6), 471-482
DOI 10.1080/15622975.2016.1245441, PubMed 27712130
Serum concentrations of mood stabilizers are associated with memory, but not other cognitive domains in psychosis spectrum disorders; explorative analyses in a naturalistic setting
Int J Bipolar Disord, 4 (1), 24
DOI 10.1186/s40345-016-0067-z, PubMed 27858347
A history of childhood trauma is associated with slower improvement rates: Findings from a one-year follow-up study of patients with a first-episode psychosis
BMC Psychiatry, 16, 126
DOI 10.1186/s12888-016-0827-4, PubMed 27146044
Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014
Psychiatr Genet, 26 (1), 1-47
DOI 10.1097/YPG.0000000000000112, PubMed 26565519
The role of childhood trauma in bipolar disorders
Int J Bipolar Disord, 4 (1), 2
DOI 10.1186/s40345-015-0042-0, PubMed 26763504
Publications 2015
Polygenic risk scores in bipolar disorder subgroups
J Affect Disord, 183, 310-4
DOI 10.1016/j.jad.2015.05.021, PubMed 26047958
Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls
Schizophr Res, 165 (2-3), 188-94
DOI 10.1016/j.schres.2015.04.004, PubMed 25956633
Serum level of venlafaxine is associated with better memory in psychotic disorders
Schizophr Res, 169 (1-3), 386-392
DOI 10.1016/j.schres.2015.10.021, PubMed 26516101
Publications 2014
Childhood trauma mediates the association between ethnic minority status and more severe hallucinations in psychotic disorder
Psychol Med, 45 (1), 133-42
DOI 10.1017/S0033291714001135, PubMed 25065296
Anomalous self-experience and childhood trauma in first-episode schizophrenia
Compr Psychiatry, 56, 35-41
DOI 10.1016/j.comppsych.2014.10.005, PubMed 25458477
Altered systemic cortisol metabolism in bipolar disorder and schizophrenia spectrum disorders
J Psychiatr Res, 52, 57-62
DOI 10.1016/j.jpsychires.2014.01.017, PubMed 24534618
Affective lability in patients with bipolar disorders is associated with high levels of childhood trauma
Psychiatry Res, 218 (1-2), 252-5
DOI 10.1016/j.psychres.2014.03.046, PubMed 24803185
A systematic review of cognitive function in first-episode psychosis, including a discussion on childhood trauma, stress, and inflammation
Front Psychiatry, 4, 182
DOI 10.3389/fpsyt.2013.00182, PubMed 24409157
Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders
J Psychiatr Res, 59, 14-21
DOI 10.1016/j.jpsychires.2014.08.011, PubMed 25246365
Psychometric properties of the Affective Lability Scale (54 and 18-item version) in patients with bipolar disorder, first-degree relatives, and healthy controls
J Affect Disord, 172, 375-80
DOI 10.1016/j.jad.2014.10.028, PubMed 25451440
Publications 2013
Childhood trauma is associated with severe clinical characteristics of bipolar disorders
J Clin Psychiatry, 74 (10), 991-8
DOI 10.4088/JCP.13m08353, PubMed 24229750
Indications of a dose-response relationship between cannabis use and age at onset in bipolar disorder
Psychiatry Res, 215 (1), 101-4
DOI 10.1016/j.psychres.2013.10.029, PubMed 24262665
Patterns of childhood adverse events are associated with clinical characteristics of bipolar disorder
BMC Psychiatry, 13, 97
DOI 10.1186/1471-244X-13-97, PubMed 23522391
Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders
Psychol Med, 44 (8), 1653-62
DOI 10.1017/S0033291713002316, PubMed 24028906
BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses
Prog Neuropsychopharmacol Biol Psychiatry, 46, 181-8
DOI 10.1016/j.pnpbp.2013.07.008, PubMed 23876786
Publications 2012
High prevalence of childhood trauma in patients with schizophrenia spectrum and affective disorder
Compr Psychiatry, 54 (2), 123-7
DOI 10.1016/j.comppsych.2012.06.009, PubMed 22901835
Is deterioration of IQ a feature of first episode psychosis and how can we measure it?
Schizophr Res, 137 (1-3), 104-9
DOI 10.1016/j.schres.2012.01.041, PubMed 22341899
Is there a link between childhood trauma, cognition, and amygdala and hippocampus volume in first-episode psychosis?
Schizophr Res, 137 (1-3), 73-9
DOI 10.1016/j.schres.2012.01.035, PubMed 22353995
Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?
Psychiatry Res, 198 (3), 495-500
DOI 10.1016/j.psychres.2011.12.045, PubMed 22472845
Publications 2011
Childhood trauma and cognitive function in first-episode affective and non-affective psychosis
Schizophr Res, 129 (1), 12-9
DOI 10.1016/j.schres.2011.03.017, PubMed 21601792
Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders
Schizophr Bull, 38 (1), 15-22
DOI 10.1093/schbul/sbr113, PubMed 21908796
Publications 2010
Higher cortisol levels are associated with smaller left hippocampal volume in first-episode psychosis
Schizophr Res, 119 (1-3), 75-8
DOI 10.1016/j.schres.2009.12.021, PubMed 20071148
Publications 2009
Abnormal cortisol levels during the day and cortisol awakening response in first-episode psychosis: the role of stress and of antipsychotic treatment
Schizophr Res, 116 (2-3), 234-42
DOI 10.1016/j.schres.2009.08.013, PubMed 19751968