Visting address: Kirkeveien 166 Bygg 49 0450 Oslo
Postal adress: Oslo Universitetssykehus Postboks 4956 Nydalen 0424 Oslo
Publications 2024
COSGAP: COntainerized Statistical Genetics Analysis Pipelines
Bioinform Adv, 4 (1), vbae067
DOI 10.1093/bioadv/vbae067, PubMed 38808072
Finemap-MiXeR: A variational Bayesian approach for genetic finemapping
PLoS Genet, 20 (8), e1011372
DOI 10.1371/journal.pgen.1011372, PubMed 39146375
Poor muscle health and cardiometabolic risks associated with antidepressant treatment
Obesity (Silver Spring), 32 (10), 1857-1869
DOI 10.1002/oby.24085, PubMed 39315407
Caudate nucleus volume in medicated and unmedicated patients with early- and adult-onset schizophrenia
Sci Rep, 14 (1), 22755
DOI 10.1038/s41598-024-73322-x, PubMed 39353988
Increased Herpes simplex virus 1, Toxoplasma gondii and Cytomegalovirus antibody concentrations in severe mental illness
Transl Psychiatry, 14 (1), 498
DOI 10.1038/s41398-024-03198-y, PubMed 39695093
Toxoplasma gondii infection associated with inflammasome activation and neuronal injury
Sci Rep, 14 (1), 5327
DOI 10.1038/s41598-024-55887-9, PubMed 38438515
Genetic associations with psychosis and affective disturbance in Alzheimer's disease
Alzheimers Dement (N Y), 10 (2), e12472
DOI 10.1002/trc2.12472, PubMed 38784964
Assessing causal links between age at menarche and adolescent mental health: a Mendelian randomisation study
BMC Med, 22 (1), 155
DOI 10.1186/s12916-024-03361-8, PubMed 38609914
The effects of oxytocin administration on social and routinized behaviors in autism: A preregistered systematic review and meta-analysis
Psychoneuroendocrinology, 167, 107067
DOI 10.1016/j.psyneuen.2024.107067, PubMed 38815399
The genetic landscape of basal ganglia and implications for common brain disorders
Nat Commun, 15 (1), 8476
DOI 10.1038/s41467-024-52583-0, PubMed 39353893
Childhood trajectories of emotional and behavioral difficulties are related to polygenic liability for mood and anxiety disorders
J Child Psychol Psychiatry (in press)
DOI 10.1111/jcpp.14063, PubMed 39462222
Mental illness and COVID-19 vaccination: a multinational investigation of observational & register-based data
Nat Commun, 15 (1), 8124
DOI 10.1038/s41467-024-52342-1, PubMed 39327436
Altered Sex Differences in Hippocampal Subfield Volumes in Schizophrenia
Schizophr Bull, 50 (1), 107-119
DOI 10.1093/schbul/sbad091, PubMed 37354490
Dissecting unique and common variance across body and brain health indicators using age prediction
Hum Brain Mapp, 45 (6), e26685
DOI 10.1002/hbm.26685, PubMed 38647042
Hypothalamic subunit volumes and relations to violence and psychopathy in male offenders with or without a psychotic disorder
Eur Arch Psychiatry Clin Neurosci (in press)
DOI 10.1007/s00406-023-01725-4, PubMed 38353675
Distinct genomic signatures and modifiable risk factors underly the comorbidity between major depressive disorder and cardiovascular disease
medRxiv
DOI 10.1101/2023.09.01.23294931, PubMed 37693619
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease
Nat Cardiovasc Res, 3 (6), 754-769
DOI 10.1038/s44161-024-00488-y, PubMed 38898929
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease
Nat Cardiovasc Res, 3 (6), 754-769
DOI 10.1038/s44161-024-00488-y, PubMed 39215135
A 10-Year Longitudinal Study of Brain Cortical Thickness in People with First-Episode Psychosis Using Normative Models
Schizophr Bull, 51 (1), 95-107
DOI 10.1093/schbul/sbae107, PubMed 38970378
Youth Psychotic Experiences: Diagnostic Associations and Evaluation of the CAPE-16
medRxiv
DOI 10.1101/2024.04.18.24306017, PubMed 38699352
Association of psychological problems for which help was sought with physical illness
Am J Prev Med (in press)
DOI 10.1016/j.amepre.2024.12.004, PubMed 39667710
Depression, anxiety and brain volume after hearing loss and tinnitus: cohort study in the UK Biobank
BJPsych Open, 10 (2), e37
DOI 10.1192/bjo.2023.634, PubMed 38297917
Peripheral vertigo and subsequent risk of depression and anxiety disorders: a prospective cohort study using the UK Biobank
BMC Med, 22 (1), 63
DOI 10.1186/s12916-023-03179-w, PubMed 38336700
Linking menopause-related factors, history of depression, APOE ε4, and proxies of biological aging in the UK biobank cohort
Horm Behav, 164, 105596
DOI 10.1016/j.yhbeh.2024.105596, PubMed 38944998
Mendelian randomization analysis of maternal coffee consumption during pregnancy on offspring neurodevelopmental difficulties in the Norwegian Mother, Father and Child Cohort Study (MoBa)
Psychol Med, 54 (12), 1-14 (in press)
DOI 10.1017/S0033291724002216, PubMed 39382486
Changes in pain during a depressive episode and relationship to cytokine levels in major depressive disorder
Nord J Psychiatry, 78 (3), 181-188
DOI 10.1080/08039488.2023.2290654, PubMed 38251060
Medical comorbidities in bipolar disorder (BIPCOM): clinical validation of risk factors and biomarkers to improve prevention and treatment. Study protocol
Int J Bipolar Disord, 12 (1), 15
DOI 10.1186/s40345-024-00337-8, PubMed 38703295
White matter microstructure in obesity and bipolar disorders: an ENIGMA bipolar disorder working group study in 2186 individuals
Mol Psychiatry (in press)
DOI 10.1038/s41380-024-02784-2, PubMed 39501059
Multimodal workflows optimally predict response to repetitive transcranial magnetic stimulation in patients with schizophrenia: a multisite machine learning analysis
Transl Psychiatry, 14 (1), 196
DOI 10.1038/s41398-024-02903-1, PubMed 38664377
Genetic overlap between Alzheimer's disease and immune-mediated diseases: an atlas of shared genetic determinants and biological convergence
Mol Psychiatry, 29 (8), 2447-2458
DOI 10.1038/s41380-024-02510-y, PubMed 38499654
Normative Modeling of Brain Morphometry in Clinical High Risk for Psychosis
JAMA Psychiatry, 81 (1), 77-88
DOI 10.1001/jamapsychiatry.2023.3850, PubMed 37819650
Examining intergenerational risk factors for conduct problems using polygenic scores in the Norwegian Mother, Father and Child Cohort Study
Mol Psychiatry, 29 (4), 951-961
DOI 10.1038/s41380-023-02383-7, PubMed 38225381
Improved functional mapping of complex trait heritability with GSA-MiXeR implicates biologically specific gene sets
Nat Genet, 56 (6), 1310-1318
DOI 10.1038/s41588-024-01771-1, PubMed 38831010
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
Nat Genet, 56 (11), 2333-2344
DOI 10.1038/s41588-024-01951-z, PubMed 39433889
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
medRxiv
DOI 10.1101/2024.08.13.24311922, PubMed 39371125
Linking sarcopenia, brain structure and cognitive performance: a large-scale UK Biobank study
Brain Commun, 6 (2), fcae083
DOI 10.1093/braincomms/fcae083, PubMed 38510210
Large-scale brainstem neuroimaging and genetic analyses provide new insights into the neuronal mechanisms of hypertension
HGG Adv, 100392 (in press)
DOI 10.1016/j.xhgg.2024.100392, PubMed 39663699
Genetic and phenotypic heterogeneity in early neurodevelopmental traits in the Norwegian Mother, Father and Child Cohort Study
Mol Autism, 15 (1), 25
DOI 10.1186/s13229-024-00599-0, PubMed 38849897
Author Correction: Characterization of the genetic architecture of infant and early childhood body mass index
Nat Metab, 6 (2), 378
DOI 10.1038/s42255-024-01004-z, PubMed 38337098
Impaired glucose tolerance and cardiovascular risk factors in relation to infertility: a Mendelian randomization analysis in the Norwegian Mother, Father, and Child Cohort Study
Hum Reprod, 39 (2), 436-441
DOI 10.1093/humrep/dead234, PubMed 37949105
Parental genetically predicted liability for coronary heart disease and risk of adverse pregnancy outcomes: a cohort study
BMC Med, 22 (1), 35
DOI 10.1186/s12916-023-03223-9, PubMed 38273336
Placental efflux transporters and antiseizure or antidepressant medication use impact birth weight in MoBa cohort
iScience, 27 (3), 109285
DOI 10.1016/j.isci.2024.109285, PubMed 38455980
Incidence and Genetic Risk of Juvenile Idiopathic Arthritis in Norway by Latitude
Arthritis Rheumatol (in press)
DOI 10.1002/art.43040, PubMed 39431377
Corrigendum to "Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders" [Psychoneuroendocrinology 157 (2023) 106368]
Psychoneuroendocrinology, 162, 106980
DOI 10.1016/j.psyneuen.2024.106980, PubMed 38336601
Parental education and children's depression, anxiety, and ADHD traits, a within-family study in MoBa
NPJ Sci Learn, 9 (1), 46
DOI 10.1038/s41539-024-00260-8, PubMed 39025869
Gene-based burden tests of rare germline variants identify six cancer susceptibility genes
Nat Genet, 56 (11), 2422-2433
DOI 10.1038/s41588-024-01966-6, PubMed 39472694
Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development
Neurobiol Dis, 203, 106750
DOI 10.1016/j.nbd.2024.106750, PubMed 39608471
Neurostructural subgroup in 4291 individuals with schizophrenia identified using the subtype and stage inference algorithm
Nat Commun, 15 (1), 5996
DOI 10.1038/s41467-024-50267-3, PubMed 39013848
Sex differences in autonomic adverse effects related to antipsychotic treatment and associated hormone profiles
Schizophrenia (Heidelb), 10 (1), 6
DOI 10.1038/s41537-023-00430-4, PubMed 38182592
Cortical thickness and sub-cortical volumes in post-H1N1 narcolepsy type 1: A brain-wide MRI case-control study
Sleep Med, 116, 81-89
DOI 10.1016/j.sleep.2024.02.031, PubMed 38432031
Assessing regional intracortical myelination in schizophrenia spectrum and bipolar disorders using the optimized T1w/T2w-ratio
Psychol Med, 54 (10), 2369-2379
DOI 10.1017/S0033291724000503, PubMed 38563302
Dissecting the Shared Genetic Architecture of Common Epilepsies With Cortical Brain Morphology
Neurol Genet, 10 (3), e200143
DOI 10.1212/NXG.0000000000200143, PubMed 38817246
Unraveling the shared genetics of common epilepsies and general cognitive ability
medRxiv
DOI 10.1101/2024.03.25.24304773, PubMed 38585944
Unraveling the shared genetics of common epilepsies and general cognitive ability
Seizure, 122, 105-112
DOI 10.1016/j.seizure.2024.09.016, PubMed 39388989
Associations between parental psychopathology and youth functional emotion regulation brain networks
Dev Cogn Neurosci, 70, 101476
DOI 10.1016/j.dcn.2024.101476, PubMed 39541797
The role of functional emotion circuits in distinct dimensions of psychopathology in youth
Transl Psychiatry, 14 (1), 317
DOI 10.1038/s41398-024-03036-1, PubMed 39095355
Genome-wide association analyses using machine learning-based phenotyping reveal genetic architecture of occupational creativity and overlap with psychiatric disorders
Psychiatry Res, 333, 115753
DOI 10.1016/j.psychres.2024.115753, PubMed 38335777
Genome-wide meta-analyses of non-response to antidepressants identify novel loci and potential drugs
medRxiv
DOI 10.1101/2024.07.13.24310361, PubMed 39072048
Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study
Neuropsychopharmacology, 49 (7), 1113-1119
DOI 10.1038/s41386-023-01792-0, PubMed 38184734
How Real-World Data Can Facilitate the Development of Precision Medicine Treatment in Psychiatry
Biol Psychiatry, 96 (7), 543-551
DOI 10.1016/j.biopsych.2024.01.001, PubMed 38185234
High-effect gene-coding variants impact cognition, mental well-being, and neighborhood safety substrates in brain morphology
medRxiv
DOI 10.1101/2024.05.21.24307729, PubMed 38826357
Using rare genetic mutations to revisit structural brain asymmetry
Nat Commun, 15 (1), 2639
DOI 10.1038/s41467-024-46784-w, PubMed 38531844
Author Correction: Using rare genetic mutations to revisit structural brain asymmetry
Nat Commun, 15 (1), 3098
DOI 10.1038/s41467-024-47545-5, PubMed 38600109
Distinct Longitudinal Brain White Matter Microstructure Changes and Associated Polygenic Risk of Common Psychiatric Disorders and Alzheimer's Disease in the UK Biobank
Biol Psychiatry Glob Open Sci, 4 (4), 100323
DOI 10.1016/j.bpsgos.2024.100323, PubMed 39132576
Brain asymmetries from mid- to late life and hemispheric brain age
Nat Commun, 15 (1), 956
DOI 10.1038/s41467-024-45282-3, PubMed 38302499
Fine-mapping genomic loci refines bipolar disorder risk genes
medRxiv
DOI 10.1101/2024.02.12.24302716, PubMed 38405768
X-chromosome-wide association study for Alzheimer's disease
Mol Psychiatry (in press)
DOI 10.1038/s41380-024-02838-5, PubMed 39633006
Genome-wide association analysis of treatment resistant schizophrenia for variant discovery and polygenic assessment
Hum Genomics, 18 (1), 108
DOI 10.1186/s40246-024-00673-x, PubMed 39334510
Rapid Metabolism Underlying Subtherapeutic Serum Levels of Atypical Antipsychotics Preceding Clozapine Treatment: A Retrospective Analysis of Real-World Data
CNS Drugs, 38 (6), 473-480
DOI 10.1007/s40263-024-01079-y, PubMed 38635089
Constructing personalized characterizations of structural brain aberrations in patients with dementia using explainable artificial intelligence
NPJ Digit Med, 7 (1), 110
DOI 10.1038/s41746-024-01123-7, PubMed 38698139
Perinatal depression and risk of maternal cardiovascular disease: a Swedish nationwide study
Eur Heart J, 45 (31), 2865-2875
DOI 10.1093/eurheartj/ehae170, PubMed 38889798
Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia
Am J Hum Genet, 111 (7), 1316-1329
DOI 10.1016/j.ajhg.2024.05.017, PubMed 38889728
Principal component analysis as an efficient method for capturing multivariate brain signatures of complex disorders-ENIGMA study in people with bipolar disorders and obesity
Hum Brain Mapp, 45 (8), e26682
DOI 10.1002/hbm.26682, PubMed 38825977
Quantifying the relative importance of genetics and environment on the comorbidity between mental and cardiometabolic disorders using 17 million Scandinavians
Nat Commun, 15 (1), 5064
DOI 10.1038/s41467-024-49507-3, PubMed 38871766
Quantifying the Relative Importance of Genetics and Environment on the Comorbidity between Mental- and Cardiometabolic Disorders: A Comprehensive Analysis of National Register Data from 17 million Scandinavians
medRxiv
DOI 10.1101/2024.02.29.24303530, PubMed 38464139
Corrigendum to "Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study" [Schizophr. Res. volume 225 (May 2023) 173-181]
Schizophr Res, 270, 495-496
DOI 10.1016/j.schres.2024.06.029, PubMed 39079354
Telomere biology and its maintenance in schizophrenia spectrum disorders: Exploring links to cognition
Schizophr Res, 272, 89-95
DOI 10.1016/j.schres.2024.08.011, PubMed 39208769
Neurocognitive function and delusion severity in schizophrenia spectrum disorders
Schizophr Res, 270, 172-177
DOI 10.1016/j.schres.2024.06.028, PubMed 38917554
A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans
Commun Biol, 7 (1), 432
DOI 10.1038/s42003-024-06101-z, PubMed 38594418
Defining Suicidal Thought and Behavior Phenotypes for Genetic Studies
medRxiv
DOI 10.1101/2024.07.27.24311110, PubMed 39132474
Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modeling
Proc Natl Acad Sci U S A, 121 (34), e2312511121
DOI 10.1073/pnas.2312511121, PubMed 39141354
Current Auditory Hallucinations Are Not Associated With Specific White Matter Diffusion Alterations in Schizophrenia
Schizophr Bull Open, 5 (1), sgae008
DOI 10.1093/schizbullopen/sgae008, PubMed 39144116
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder
Nat Genet, 56 (5), 792-808
DOI 10.1038/s41588-024-01707-9, PubMed 38637617
More than nature and nurture, indirect genetic effects on children's academic achievement are consequences of dynastic social processes
Nat Hum Behav, 8 (4), 771-778
DOI 10.1038/s41562-023-01796-2, PubMed 38225408
Parental education and income are linked to offspring cortical brain structure and psychopathology at 9-11 years
JCPP Adv, 4 (1), e12220
DOI 10.1002/jcv2.12220, PubMed 38486948
Pleiotropy with sex-specific traits reveals genetic aspects of sex differences in Parkinson's disease
Brain, 147 (3), 858-870
DOI 10.1093/brain/awad297, PubMed 37671566
Homozygosity for a stop-gain variant in CCDC201 causes primary ovarian insufficiency
Nat Genet, 56 (9), 1804-1810
DOI 10.1038/s41588-024-01885-6, PubMed 39192094
FEMA: Fast and efficient mixed-effects algorithm for large sample whole-brain imaging data
Hum Brain Mapp, 45 (2), e26579
DOI 10.1002/hbm.26579, PubMed 38339910
Leveraging the Genetics of Psychiatric Disorders to Prioritize Potential Drug Targets and Compounds
medRxiv
DOI 10.1101/2024.09.24.24314069, PubMed 39399035
Mismatch negativity and polygenic risk scores for schizophrenia and bipolar disorder
Schizophr Res, 264, 314-326
DOI 10.1016/j.schres.2024.01.013, PubMed 38215567
Eating Problems Among Adolescent Boys and Girls Before and During the Covid-19 Pandemic
Int J Eat Disord (in press)
DOI 10.1002/eat.24314, PubMed 39473346
Identification of Transcripts with Shared Roles in the Pathogenesis of Postmenopausal Osteoporosis and Cardiovascular Disease
Int J Mol Sci, 25 (10)
DOI 10.3390/ijms25105554, PubMed 38791593
Hypothalamic Subunit Volumes in Schizophrenia and Bipolar Spectrum Disorders
Schizophr Bull, 50 (3), 533-544
DOI 10.1093/schbul/sbad176, PubMed 38206841
An evolutionary timeline of the oxytocin signaling pathway
Commun Biol, 7 (1), 471
DOI 10.1038/s42003-024-06094-9, PubMed 38632466
Multiscale heterogeneity of white matter morphometry in psychiatric disorders
bioRxiv
DOI 10.1101/2024.08.04.606523, PubMed 39149253
Dissecting the genetic overlap between three complex phenotypes with trivariate MiXeR
medRxiv
DOI 10.1101/2024.02.23.24303236, PubMed 38464132
Prescriptions of psychotropic and somatic medications among patients with severe mental disorders and healthy controls in a naturalistic study
Nord J Psychiatry, 78 (3), 212-219
DOI 10.1080/08039488.2024.2305806, PubMed 38306243
GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis
Commun Biol, 7 (1), 504
DOI 10.1038/s42003-024-06207-4, PubMed 38671141
Partitioning variance in cortical morphometry into genetic, environmental, and subject-specific components
Cereb Cortex, 34 (6)
DOI 10.1093/cercor/bhae234, PubMed 38850213
Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism
Nat Commun, 15 (1), 7550
DOI 10.1038/s41467-024-51947-w, PubMed 39214992
Homozygosity for R47H in TREM2 and the Risk of Alzheimer's Disease
N Engl J Med, 390 (23), 2217-2219
DOI 10.1056/NEJMc2314334, PubMed 38899702
Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci
medRxiv
DOI 10.1101/2024.03.13.24304161, PubMed 38712091
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling
medRxiv
DOI 10.1101/2024.07.03.24309466, PubMed 39006447
Characterizing the polygenic overlap and shared loci between rheumatoid arthritis and cardiovascular diseases
BMC Med, 22 (1), 152
DOI 10.1186/s12916-024-03376-1, PubMed 38589871
NLRP3 inflammasome mediates astroglial dysregulation of innate and adaptive immune responses in schizophrenia
Brain Behav Immun, 124, 144-156 (in press)
DOI 10.1016/j.bbi.2024.11.030, PubMed 39617069
Elevated levels of peripheral and central nervous system immune markers reflect innate immune dysregulation in autism spectrum disorder
Psychiatry Res, 342, 116245
DOI 10.1016/j.psychres.2024.116245, PubMed 39481220
Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain
Brain Behav Immun, 118, 287-299
DOI 10.1016/j.bbi.2024.03.014, PubMed 38461955
Longitudinal course of inflammatory-cognitive subgroups across first treatment severe mental illness and healthy controls
Psychol Med, 54 (12), 1-11 (in press)
DOI 10.1017/S003329172400206X, PubMed 39354711
Genome-wide determinants of mortality and motor progression in Parkinson's disease
NPJ Parkinsons Dis, 10 (1), 113
DOI 10.1038/s41531-024-00729-8, PubMed 38849413
Identification of Novel Genomic Loci for Anxiety and Extensive Genetic Overlap with Psychiatric Disorders
medRxiv
DOI 10.1101/2023.09.01.23294920, PubMed 37693403
Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders
Psychiatry Clin Neurosci, 78 (12), 783-791
DOI 10.1111/pcn.13742, PubMed 39301620
Comorbidity alters the genetic relationship between anxiety disorders and major depression
medRxiv
DOI 10.1101/2024.11.19.24317523, PubMed 39606413
Sex effects on DNA methylation affect discovery in epigenome-wide association study of schizophrenia
Mol Psychiatry, 29 (8), 2467-2477
DOI 10.1038/s41380-024-02513-9, PubMed 38503926
Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study
Nat Commun, 15 (1), 2655
DOI 10.1038/s41467-024-46817-4, PubMed 38531894
Delirium is frequently underdiagnosed among older hospitalised patients despite available information in hospital medical records
Age Ageing, 53 (2)
DOI 10.1093/ageing/afae006, PubMed 38342753
Clustering Schizophrenia Genes by Their Temporal Expression Patterns Aids Functional Interpretation
Schizophr Bull, 50 (2), 327-338
DOI 10.1093/schbul/sbad140, PubMed 37824720
Cellular adhesion molecules in drug-naïve and previously medicated patients with schizophrenia-spectrum disorders
Schizophr Res, 267, 223-229
DOI 10.1016/j.schres.2024.03.029, PubMed 38574562
History of childhood maltreatment associated with hospitalization or death due to COVID-19: a cohort study
BMC Med, 22 (1), 319
DOI 10.1186/s12916-024-03399-8, PubMed 39113083
Genome-wide association meta-analysis identifies five loci associated with postpartum hemorrhage
Nat Genet, 56 (8), 1597-1603
DOI 10.1038/s41588-024-01839-y, PubMed 39039282
Genomic insights into the shared and distinct genetic architecture of cognitive function and schizophrenia
Sci Rep, 14 (1), 15356
DOI 10.1038/s41598-024-66085-y, PubMed 38961113
Divergent epigenetic responses to perinatal asphyxia in severe mental disorders
Transl Psychiatry, 14 (1), 16
DOI 10.1038/s41398-023-02709-7, PubMed 38191519
Gut microbial diversity moderates polygenic risk of schizophrenia
Front Psychiatry, 15, 1275719
DOI 10.3389/fpsyt.2024.1275719, PubMed 38362027
Using brain structural neuroimaging measures to predict psychosis onset for individuals at clinical high-risk
Mol Psychiatry, 29 (5), 1465-1477
DOI 10.1038/s41380-024-02426-7, PubMed 38332374
Publications 2023
A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population
Cancers (Basel), 15 (16)
DOI 10.3390/cancers15164124, PubMed 37627152
Longitudinal Transcriptomic Analysis of Human Cortical Spheroids Identifies Axonal Dysregulation in the Prenatal Brain as a Mediator of Genetic Risk for Schizophrenia
Biol Psychiatry, 95 (7), 687-698
DOI 10.1016/j.biopsych.2023.08.017, PubMed 37661009
New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications
World Psychiatry, 22 (1), 4-24
DOI 10.1002/wps.21034, PubMed 36640404
Association between cannabis use and symptom dimensions in schizophrenia spectrum disorders: an individual participant data meta-analysis on 3053 individuals
EClinicalMedicine, 64, 102199
DOI 10.1016/j.eclinm.2023.102199, PubMed 37731936
Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood
Transl Psychiatry, 13 (1), 222
DOI 10.1038/s41398-023-02522-2, PubMed 37353490
Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia nervosa
Transl Psychiatry, 13 (1), 291
DOI 10.1038/s41398-023-02585-1, PubMed 37658054
Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder
Int J Bipolar Disord, 11 (1), 22
DOI 10.1186/s40345-023-00303-w, PubMed 37347392
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
Nat Genet, 55 (11), 1807-1819
DOI 10.1038/s41588-023-01520-w, PubMed 37798380
Puberty differentially predicts brain maturation in male and female youth: A longitudinal ABCD Study
Dev Cogn Neurosci, 61, 101261
DOI 10.1016/j.dcn.2023.101261, PubMed 37295068
Psychometric Properties and Diagnostic Associations of the Short-Form Community Assessment of Psychic Experiences in a Population-Based Sample of 29 021 Adult Men
Schizophr Bull, 49 (5), 1229-1238
DOI 10.1093/schbul/sbad074, PubMed 37262330
Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura
Nat Genet, 55 (11), 1843-1853
DOI 10.1038/s41588-023-01538-0, PubMed 37884687
No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank
Transl Psychiatry, 13 (1), 61
DOI 10.1038/s41398-023-02358-w, PubMed 36807331
Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers
Biol Psychiatry, 95 (2), 147-160
DOI 10.1016/j.biopsych.2023.08.018, PubMed 37661008
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
Nat Commun, 14 (1), 6172
DOI 10.1038/s41467-023-41180-2, PubMed 37794016
Predictors of Functional Impairment in Bipolar Disorder: Results From 13 Cohorts From Seven Countries by the Global Bipolar Cohort Collaborative
Focus (Am Psychiatr Publ), 21 (4), 444-452
DOI 10.1176/appi.focus.23021021, PubMed 38694997
Distributed genetic effects of the corpus callosum subregions suggest links to neuropsychiatric disorders and related traits
Acta Neuropsychiatr, 1-8 (in press)
DOI 10.1017/neu.2023.32, PubMed 37612147
The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study
Lancet Psychiatry, 10 (6), 441-451
DOI 10.1016/S2215-0366(23)00143-8, PubMed 37208114
Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
Nat Commun, 14 (1), 716
DOI 10.1038/s41467-023-36192-x, PubMed 36759603
Bounding the average causal effect in Mendelian randomisation studies with multiple proposed instruments: An application to prenatal alcohol exposure and attention deficit hyperactivity disorder
Paediatr Perinat Epidemiol, 37 (4), 326-337
DOI 10.1111/ppe.12951, PubMed 36722651
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors
Am J Psychiatry, 180 (10), 723-738
DOI 10.1176/appi.ajp.21121266, PubMed 37777856
Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease
JAMA Netw Open, 6 (5), e2313734
DOI 10.1001/jamanetworkopen.2023.13734, PubMed 37195665
Associations Between Clinical Insight and History of Severe Violence in Patients With Psychosis
Schizophr Bull Open, 4 (1), sgad011
DOI 10.1093/schizbullopen/sgad011, PubMed 39145347
Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system
Neurobiol Dis, 183, 106174
DOI 10.1016/j.nbd.2023.106174, PubMed 37286172
Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression
Am J Psychiatry, 180 (12), 884-895
DOI 10.1176/appi.ajp.20230053, PubMed 37849304
Intergenerational effects of parental educational attainment on parenting and childhood educational outcomes: Evidence from MoBa using within-family Mendelian randomization
medRxiv
DOI 10.1101/2023.02.22.23285699, PubMed 36865116
Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders
Psychoneuroendocrinology, 157, 106368
DOI 10.1016/j.psyneuen.2023.106368, PubMed 37659117
Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy
Nat Hum Behav, 7 (9), 1584-1600
DOI 10.1038/s41562-023-01630-9, PubMed 37365406
Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy
BMC Psychiatry, 23 (1), 659
DOI 10.1186/s12888-023-05154-4, PubMed 37674162
Genome-wide analyses reveal shared genetic architecture and novel risk loci between opioid use disorder and general cognitive ability
Drug Alcohol Depend, 256, 111058
DOI 10.1016/j.drugalcdep.2023.111058, PubMed 38244365
Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression
Addict Biol, 28 (6), e13282
DOI 10.1111/adb.13282, PubMed 37252880
Systemic immune profile in Prader-Willi syndrome: elevated matrix metalloproteinase and myeloperoxidase and reduced macrophage inhibitory factor
Orphanet J Rare Dis, 18 (1), 185
DOI 10.1186/s13023-023-02730-5, PubMed 37430349
Bidirectional genetic overlap between autism spectrum disorder and cognitive traits
Transl Psychiatry, 13 (1), 295
DOI 10.1038/s41398-023-02563-7, PubMed 37709755
Normative modeling of brain morphometry in Clinical High-Risk for Psychosis
bioRxiv
DOI 10.1101/2023.01.17.523348, PubMed 36711551
Intra- and inter-individual cognitive variability in schizophrenia and bipolar spectrum disorder: an investigation across multiple cognitive domains
Schizophrenia (Heidelb), 9 (1), 89
DOI 10.1038/s41537-023-00414-4, PubMed 38110366
Etiologic Studies of Premenstrual Disorders Require Prospective Confirmation of Affective Cyclicity-Reply
JAMA Psychiatry, 80 (11), 1175-1176
DOI 10.1001/jamapsychiatry.2023.3290, PubMed 37703043
Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci
Schizophr Bull, 49 (6), 1654-1664
DOI 10.1093/schbul/sbad063, PubMed 37163672
Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders
JAMA Psychiatry, 80 (7), 738-742
DOI 10.1001/jamapsychiatry.2023.1137, PubMed 37163253
Do environmental effects indexed by parental genetic variation influence common psychiatric symptoms in childhood?
Transl Psychiatry, 13 (1), 94
DOI 10.1038/s41398-023-02348-y, PubMed 36934099
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
Schizophr Bull, 49 (3), 635-645
DOI 10.1093/schbul/sbac191, PubMed 36462169
Two neurostructural subtypes: results of machine learning on brain images from 4,291 individuals with schizophrenia
medRxiv
DOI 10.1101/2023.10.11.23296862, PubMed 37873296
Precision medicine in complex diseases-Molecular subgrouping for improved prediction and treatment stratification
J Intern Med, 294 (4), 378-396
DOI 10.1111/joim.13640, PubMed 37093654
Leveraging genetic overlap between irritability and psychiatric disorders to identify genetic variants of major psychiatric disorders
Exp Mol Med, 55 (6), 1193-1202
DOI 10.1038/s12276-023-01005-0, PubMed 37258574
Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders
Brain, 146 (8), 3392-3403
DOI 10.1093/brain/awad038, PubMed 36757824
Rare CNVs and phenome-wide profiling highlight brain structural divergence and phenotypical convergence
Nat Hum Behav, 7 (6), 1001-1017
DOI 10.1038/s41562-023-01541-9, PubMed 36864136
Using rare genetic mutations to revisit structural brain asymmetry
bioRxiv
DOI 10.1101/2023.04.17.537199, PubMed 37131672
Brain-wide associations between white matter and age highlight the role of fornix microstructure in brain ageing
Hum Brain Mapp, 44 (10), 4101-4119
DOI 10.1002/hbm.26333, PubMed 37195079
Bio-psycho-social factors' associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants
Front Psychol, 14, 1117732
DOI 10.3389/fpsyg.2023.1117732, PubMed 37359862
Considerations on brain age predictions from repeatedly sampled data across time
Brain Behav, 13 (10), e3219
DOI 10.1002/brb3.3219, PubMed 37587620
Subcortical Brain Alterations in Carriers of Genomic Copy Number Variants
Am J Psychiatry, 180 (9), 685-698
DOI 10.1176/appi.ajp.20220304, PubMed 37434504
Subcortical brain alterations in carriers of genomic copy number variants
medRxiv
DOI 10.1101/2023.02.14.23285913, PubMed 36865328
Combining antidepressants and attention bias modification in primary health care (DEPTREAT): Protocol for a pragmatic randomized controlled trial
Contemp Clin Trials, 133, 107326
DOI 10.1016/j.cct.2023.107326, PubMed 37652355
Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes
Proc Natl Acad Sci U S A, 120 (36), e2302720120
DOI 10.1073/pnas.2302720120, PubMed 37643212
Genetic architecture of brain age and its causal relations with brain and mental disorders
Mol Psychiatry, 28 (7), 3111-3120
DOI 10.1038/s41380-023-02087-y, PubMed 37165155
Elevated symptoms of depression and anxiety among family members and friends of critically ill COVID-19 patients - an observational study of five cohorts across four countries
Lancet Reg Health Eur, 33, 100733
DOI 10.1016/j.lanepe.2023.100733, PubMed 37953992
Mental Distress Among Norwegian Adults During the COVID-19 Pandemic: Predictors in Initial Response and Subsequent Trajectories
Int J Public Health, 68, 1606164
DOI 10.3389/ijph.2023.1606164, PubMed 38024210
Tobacco smoking related to childhood trauma mediated by cognitive control and impulsiveness in severe mental disorders
Schizophr Res, 261, 236-244
DOI 10.1016/j.schres.2023.09.041, PubMed 37806047
Visual processing deficits in patients with schizophrenia spectrum and bipolar disorders and associations with psychotic symptoms, and intellectual abilities
Heliyon, 9 (2), e13354
DOI 10.1016/j.heliyon.2023.e13354, PubMed 36825178
Mega-analysis of association between obesity and cortical morphology in bipolar disorders: ENIGMA study in 2832 participants
Psychol Med, 53 (14), 6743-6753
DOI 10.1017/S0033291723000223, PubMed 36846964
Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study
Schizophr Res, 255, 173-181
DOI 10.1016/j.schres.2023.03.020, PubMed 37001392
Telomere length and verbal learning in bipolar disorders
J Affect Disord, 339, 555-560
DOI 10.1016/j.jad.2023.07.087, PubMed 37459977
The Genetic Architecture of Amygdala Nuclei
Biol Psychiatry, 95 (1), 72-84
DOI 10.1016/j.biopsych.2023.06.022, PubMed 37391117
Brain-based gene expression of putative risk genes for anorexia nervosa
Mol Psychiatry, 28 (6), 2612-2619
DOI 10.1038/s41380-023-02110-2, PubMed 37221367
Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modelling
bioRxiv
DOI 10.1101/2023.06.14.544920, PubMed 37398070
Thalamic nuclei volumes in schizophrenia and bipolar spectrum disorders - Associations with diagnosis and clinical characteristics
Schizophr Res, 256, 26-35
DOI 10.1016/j.schres.2023.04.008, PubMed 37126979
Multi-Site Statistical Mapping of Along-Tract Microstructural Abnormalities in Bipolar Disorder with Diffusion MRI Tractometry
bioRxiv
DOI 10.1101/2023.08.17.553762, PubMed 37662230
Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders
medRxiv
DOI 10.1101/2023.08.31.23294915, PubMed 37693460
Erratum to "Parental socioeconomic status is linked to cortical microstructure and language abilities in children and adolescents" [Dev. Cogn. Neurosci. 56C (2022) 101132]
Dev Cogn Neurosci, 61, 101225
DOI 10.1016/j.dcn.2023.101225, PubMed 36870926
Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia
Psychiatry Res, 325, 115217
DOI 10.1016/j.psychres.2023.115217, PubMed 37146461
Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Nat Commun, 14 (1), 3453
DOI 10.1038/s41467-023-38951-2, PubMed 37301908
Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Nat Commun, 14 (1), 3923
DOI 10.1038/s41467-023-39492-4, PubMed 37400429
Estimating multimodal brain variability in schizophrenia spectrum disorders: A worldwide ENIGMA study
bioRxiv
DOI 10.1101/2023.09.22.559032, PubMed 37961617
Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids
Mol Psychiatry, 28 (7), 3033-3043
DOI 10.1038/s41380-023-01944-0, PubMed 36653674
Genetic liability to schizophrenia and cardiac structure and function
Lancet Psychiatry, 10 (2), 72-73
DOI 10.1016/S2215-0366(23)00009-3, PubMed 36632819
Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts
Biol Psychiatry, 95 (1), 62-71
DOI 10.1016/j.biopsych.2023.06.008, PubMed 37348803
Psychiatric disorders and brain white matter exhibit genetic overlap implicating developmental and neural cell biology
Mol Psychiatry, 28 (11), 4924-4932
DOI 10.1038/s41380-023-02264-z, PubMed 37759039
Epidemiological overview of major depressive disorder in Scandinavia using nationwide registers
Lancet Reg Health Eur, 29, 100621
DOI 10.1016/j.lanepe.2023.100621, PubMed 37265784
Mismatch negativity in schizophrenia spectrum and bipolar disorders: Group and sex differences and associations with symptom severity
Schizophr Res, 261, 80-93
DOI 10.1016/j.schres.2023.09.012, PubMed 37716205
Improved multimodal prediction of progression from MCI to Alzheimer's disease combining genetics with quantitative brain MRI and cognitive measures
Alzheimers Dement, 19 (11), 5151-5158
DOI 10.1002/alz.13112, PubMed 37132098
Polygenic risk for schizophrenia and bipolar disorder in relation to cardiovascular biomarkers
Eur Arch Psychiatry Clin Neurosci, 274 (5), 1223-1230
DOI 10.1007/s00406-023-01591-0, PubMed 37145175
Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank
BMC Psychiatry, 23 (1), 461
DOI 10.1186/s12888-023-04905-7, PubMed 37353766
Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors
Am J Psychiatry, 180 (11), 815-826
DOI 10.1176/appi.ajp.20220660, PubMed 37752828
Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium
Proc Natl Acad Sci U S A, 120 (14), e2213880120
DOI 10.1073/pnas.2213880120, PubMed 36976765
Cardiometabolic health across menopausal years is linked to white matter hyperintensities up to a decade later
Front Glob Womens Health, 4, 1320640
DOI 10.3389/fgwh.2023.1320640, PubMed 38213741
Addressing Global Environmental Challenges to Mental Health Using Population Neuroscience: A Review
JAMA Psychiatry, 80 (10), 1066-1074
DOI 10.1001/jamapsychiatry.2023.2996, PubMed 37610741
Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders
Nat Neurosci, 26 (9), 1613-1629
DOI 10.1038/s41593-023-01404-6, PubMed 37580620
The overlapping genetic architecture of psychiatric disorders and cortical brain structure
bioRxiv
DOI 10.1101/2023.10.05.561040, PubMed 37873315
COVID-19 illness severity and 2-year prevalence of physical symptoms: an observational study in Iceland, Sweden, Norway and Denmark
Lancet Reg Health Eur, 35, 100756
DOI 10.1016/j.lanepe.2023.100756, PubMed 38115966
Psychiatric disorders and subsequent risk of cardiovascular disease: a longitudinal matched cohort study across three countries
EClinicalMedicine, 61, 102063
DOI 10.1016/j.eclinm.2023.102063, PubMed 37425374
Patterns of pharmacotherapy for bipolar disorder: A GBC survey
Bipolar Disord, 26 (1), 22-32
DOI 10.1111/bdi.13366, PubMed 37463846
Relationship between function and structure in the visual cortex in healthy individuals and in patients with severe mental disorders
Psychiatry Res Neuroimaging, 332, 111633
DOI 10.1016/j.pscychresns.2023.111633, PubMed 37028226
Auditory Cortex Thickness Is Associated With N100 Amplitude in Schizophrenia Spectrum Disorders
Schizophr Bull Open, 4 (1), sgad015
DOI 10.1093/schizbullopen/sgad015, PubMed 38812720
The shared genetic risk architecture of neurological and psychiatric disorders: a genome-wide analysis
medRxiv
DOI 10.1101/2023.07.21.23292993, PubMed 37503175
Heritability Estimation of Cognitive Phenotypes in the ABCD Study® Using Mixed Models
Behav Genet, 53 (3), 169-188
DOI 10.1007/s10519-023-10141-2, PubMed 37024669
Maternal Fiber Intake During Pregnancy and Development of Attention-Deficit/Hyperactivity Disorder Symptoms Across Childhood: The Norwegian Mother, Father, and Child Cohort Study
Biol Psychiatry, 95 (9), 839-848
DOI 10.1016/j.biopsych.2023.12.017, PubMed 38142720
Genetic effects on the timing of parturition and links to fetal birth weight
Nat Genet, 55 (4), 559-567
DOI 10.1038/s41588-023-01343-9, PubMed 37012456
Author Correction: Genetic effects on the timing of parturition and links to fetal birth weight
Nat Genet, 55 (7), 1250
DOI 10.1038/s41588-023-01412-z, PubMed 37165137
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities
Schizophr Bull, 49 (5), 1345-1354
DOI 10.1093/schbul/sbad082, PubMed 37319439
The effect of maternal BMI, smoking and alcohol on congenital heart diseases: a Mendelian randomisation study
BMC Med, 21 (1), 35
DOI 10.1186/s12916-023-02731-y, PubMed 36721200
Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis
Genome Med, 15 (1), 60
DOI 10.1186/s13073-023-01212-4, PubMed 37528461
Conduct disorder - a comprehensive exploration of comorbidity patterns, genetic and environmental risk factors
Psychiatry Res, 331, 115628
DOI 10.1016/j.psychres.2023.115628, PubMed 38029627
Risk of recurrent cardiovascular events in coronary artery disease patients with Type D personality
Front Psychol, 14, 1119146
DOI 10.3389/fpsyg.2023.1119146, PubMed 37057178
Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes
Transl Psychiatry, 13 (1), 147
DOI 10.1038/s41398-023-02442-1, PubMed 37147304
Differences in white blood cell proportions between schizophrenia cases and controls are influenced by medication and variations in time of day
Transl Psychiatry, 13 (1), 211
DOI 10.1038/s41398-023-02507-1, PubMed 37330513
Delineating disorder-general and disorder-specific dimensions of psychopathology from functional brain networks in a developmental clinical sample
Dev Cogn Neurosci, 62, 101271
DOI 10.1016/j.dcn.2023.101271, PubMed 37348146
Shared pattern of impaired social communication and cognitive ability in the youth brain across diagnostic boundaries
Dev Cogn Neurosci, 60, 101219
DOI 10.1016/j.dcn.2023.101219, PubMed 36812678
TMEM161B modulates radial glial scaffolding in neocortical development
Proc Natl Acad Sci U S A, 120 (4), e2209983120
DOI 10.1073/pnas.2209983120, PubMed 36669109
Pregnancy-Associated Bleeding and Genetics: Five Sequence Variants in the Myometrium and Progesterone Signaling Pathway are associated with postpartum hemorrhage
medRxiv
DOI 10.1101/2023.08.10.23293932, PubMed 37645979
Reaction Time Variability in Children Is Specifically Associated With Attention Problems and Regional White Matter Microstructure
Biol Psychiatry Cogn Neurosci Neuroimaging, 8 (8), 832-840
DOI 10.1016/j.bpsc.2023.03.010, PubMed 37003411
Assessing the Longitudinal Associations Between Decision-Making Processes and Attention Problems in Early Adolescence
Res Child Adolesc Psychopathol, 52 (5), 803-817
DOI 10.1007/s10802-023-01148-8, PubMed 38103132
Genomic Insights into the Shared and Distinct Genetic Architecture of Cognitive Function and Schizophrenia
medRxiv
DOI 10.1101/2023.11.13.23298348, PubMed 38014326
Genome-wide association study in 404,302 individuals identifies 7 significant loci for reaction time variability
medRxiv
DOI 10.1101/2023.04.03.23288056, PubMed 37066411
Genome-wide association study in 404,302 individuals identifies 7 significant loci for reaction time variability
Mol Psychiatry, 28 (9), 4011-4019
DOI 10.1038/s41380-023-02292-9, PubMed 37864076
Associations between health behaviours, fertility and reproductive outcomes: triangulation of evidence in the Norwegian Mother, Father and Child Cohort Study (MoBa)
BMC Med, 21 (1), 125
DOI 10.1186/s12916-023-02831-9, PubMed 37013617
The impact of placental genomic risk for schizophrenia and birth asphyxia on brain development
Transl Psychiatry, 13 (1), 343
DOI 10.1038/s41398-023-02639-4, PubMed 37938559
Baseline long-term potentiation-like cortical plasticity is associated with longitudinal cortical thinning in healthy adults and in adults with bipolar disorder type II
Eur J Neurosci, 58 (3), 2824-2837
DOI 10.1111/ejn.16038, PubMed 37163975
Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders
Sci Rep, 13 (1), 13845
DOI 10.1038/s41598-023-40310-6, PubMed 37620394
Publications 2022
Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response
Schizophr Bull, 48 (1), 190-198
DOI 10.1093/schbul/sbab092, PubMed 34357384
Lifetime and point prevalence of psychotic symptoms in adults with bipolar disorders: a systematic review and meta-analysis
Psychol Med, 52 (13), 2413-2425
DOI 10.1017/S003329172200201X, PubMed 36016504
Herpes simplex virus 1 infection on grey matter and general intelligence in severe mental illness
Transl Psychiatry, 12 (1), 276
DOI 10.1038/s41398-022-02044-3, PubMed 35821107
Cytomegalovirus Infection Associated with Smaller Total Cortical Surface Area in Schizophrenia Spectrum Disorders
Schizophr Bull, 48 (5), 1164-1173
DOI 10.1093/schbul/sbac036, PubMed 35388401
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools
Brain, 145 (1), 142-153
DOI 10.1093/brain/awab267, PubMed 34273149
Distributed genetic architecture across the hippocampal formation implies common neuropathology across brain disorders
Nat Commun, 13 (1), 3436
DOI 10.1038/s41467-022-31086-w, PubMed 35705537
Childhood temperamental, emotional, and behavioral characteristics associated with mood and anxiety disorders in adolescence: A prospective study
Acta Psychiatr Scand, 147 (2), 217-228
DOI 10.1111/acps.13522, PubMed 36398468
Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis
Transl Psychiatry, 12 (1), 297
DOI 10.1038/s41398-022-02057-y, PubMed 35882855
In vivo white matter microstructure in adolescents with early-onset psychosis: a multi-site mega-analysis
Mol Psychiatry, 28 (3), 1159-1169
DOI 10.1038/s41380-022-01901-3, PubMed 36510004
Association between polarity of first episode and solar insolation in bipolar I disorder
J Psychosom Res, 160, 110982
DOI 10.1016/j.jpsychores.2022.110982, PubMed 35932492
Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults
Neuroimage Clin, 33, 102949
DOI 10.1016/j.nicl.2022.102949, PubMed 35114636
Psychopathy subdomains in violent offenders with and without a psychotic disorder
Nord J Psychiatry, 77 (4), 393-402
DOI 10.1080/08039488.2022.2128869, PubMed 36260740
New insights into the genetic etiology of Alzheimer's disease and related dementias
Nat Genet, 54 (4), 412-436
DOI 10.1038/s41588-022-01024-z, PubMed 35379992
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J. Affect. Disord., 297, 1032-1039
DOI 10.1016/j.jad.2021.08.135
Developing "MinDag" - an app to capture symptom variation and illness mechanisms in bipolar disorder
Front Med Technol, 4, 910533
DOI 10.3389/fmedt.2022.910533, PubMed 35935144
Alcohol use and alcohol use disorder differ in their genetic relationships with PTSD: A genomic structural equation modelling approach
Drug Alcohol Depend, 234, 109430
DOI 10.1016/j.drugalcdep.2022.109430, PubMed 35367939
Genetic variants associated with longitudinal changes in brain structure across the lifespan
Nat Neurosci, 25 (4), 421-432
DOI 10.1038/s41593-022-01042-4, PubMed 35383335
Predictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative
Bipolar Disord, 24 (7), 709-719
DOI 10.1111/bdi.13208, PubMed 35322518
Cytomegalovirus infection associated with lower IQ in adolescent patients with schizophrenia spectrum disorders: A preliminary report
J Psychiatr Res, 151, 571-574
DOI 10.1016/j.jpsychires.2022.05.036, PubMed 35636034
A population-wide gene-environment interaction study on how genes, schools, and residential areas shape achievement
NPJ Sci Learn, 7 (1), 29
DOI 10.1038/s41539-022-00145-8, PubMed 36302785
How interactions between ADHD and schools affect educational achievement: a family-based genetically sensitive study
J Child Psychol Psychiatry, 63 (10), 1174-1185
DOI 10.1111/jcpp.13656, PubMed 35789088
Genome-Transcriptome-Functional Connectivity-Cognition Link Differentiates Schizophrenia From Bipolar Disorder
Schizophr Bull, 48 (6), 1306-1317
DOI 10.1093/schbul/sbac088, PubMed 35988022
Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood
Mol Psychiatry, 27 (12), 5167-5176
DOI 10.1038/s41380-022-01751-z, PubMed 36100668
Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11.2 deletion syndrome: A review of ENIGMA findings
Psychiatry Clin Neurosci, 76 (5), 140-161
DOI 10.1111/pcn.13337, PubMed 35119167
Associations Between Depression and Cardiometabolic Health: A 27-Year Longitudinal Study - Corrigendum
Psychol Med, 52 (14), 3018
DOI 10.1017/S0033291722003105, PubMed 36177891
On the importance of parenting in externalizing disorders: an evaluation of indirect genetic effects in families
J Child Psychol Psychiatry, 63 (10), 1186-1195
DOI 10.1111/jcpp.13654, PubMed 35778910
Composite immune marker scores associated with severe mental disorders and illness course
Brain Behav Immun Health, 24, 100483
DOI 10.1016/j.bbih.2022.100483, PubMed 35856063
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Schizophr Bull, 48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169
Multivariate genome-wide association study on tissue-sensitive diffusion metrics highlights pathways that shape the human brain
Nat Commun, 13 (1), 2423
DOI 10.1038/s41467-022-30110-3, PubMed 35505052
Associations between brain imaging and polygenic scores of mental health and educational attainment in children aged 9-11
Neuroimage, 263, 119611
DOI 10.1016/j.neuroimage.2022.119611, PubMed 36070838
Ethical considerations for precision psychiatry: A roadmap for research and clinical practice
Eur Neuropsychopharmacol, 63, 17-34
DOI 10.1016/j.euroneuro.2022.08.001, PubMed 36041245
Lifetime Cannabis Use Is Not Associated With Negative Beliefs About Medication in Patients With First Treatment Psychosis
Front Psychiatry, 13, 824051
DOI 10.3389/fpsyt.2022.824051, PubMed 35422717
Local molecular and global connectomic contributions to cross-disorder cortical abnormalities
Nat Commun, 13 (1), 4682
DOI 10.1038/s41467-022-32420-y, PubMed 35948562
Associations Between Pregnancy-Related Predisposing Factors for Offspring Neurodevelopmental Conditions and Parental Genetic Liability to Attention-Deficit/Hyperactivity Disorder, Autism, and Schizophrenia: The Norwegian Mother, Father and Child Cohort Study (MoBa)
JAMA Psychiatry, 79 (8), 799-810
DOI 10.1001/jamapsychiatry.2022.1728, PubMed 35793100
Characterization of the genetic architecture of infant and early childhood body mass index
Nat Metab, 4 (3), 344-358
DOI 10.1038/s42255-022-00549-1, PubMed 35315439
Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
Fertil Steril, 118 (1), 180-190
DOI 10.1016/j.fertnstert.2022.04.001, PubMed 35562204
Coordinated cortical thickness alterations across six neurodevelopmental and psychiatric disorders
Nat Commun, 13 (1), 6851
DOI 10.1038/s41467-022-34367-6, PubMed 36369423
Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation
Am J Psychiatry, 179 (11), 833-843
DOI 10.1176/appi.ajp.21101051, PubMed 36069018
The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis
Am J Med Genet B Neuropsychiatr Genet, 189 (6), 207-218
DOI 10.1002/ajmg.b.32907, PubMed 35841185
Interleukin-18 signaling system links to agitation in severe mental disorders
Psychoneuroendocrinology, 140, 105721
DOI 10.1016/j.psyneuen.2022.105721, PubMed 35301151
Polygenic resilience scores capture protective genetic effects for Alzheimer's disease
Transl Psychiatry, 12 (1), 296
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Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects
Nat Genet, 54 (5), 581-592
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Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study
Elife, 11
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Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score
Prostate Cancer Prostatic Dis, 25 (4), 755-761
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Preventive Medication Patterns in Bipolar Disorder and Their Relationship With Comorbid Substance Use Disorders in a Cross-National Observational Study
Front Psychiatry, 13, 813256
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Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings
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Limited evidence for a moderating effect of HIV status on brain age in heavy episodic drinkers
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Birth order differences in education originate in postnatal environments
PNAS Nexus, 1 (2), pgac051
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Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms
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Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers
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Correction to: Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
Eur J Hum Genet, 30 (10), 1198
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Sex differences in antipsychotic-related triglyceride levels are associated with metabolic hormone differences in patients with severe mental disorders
Schizophr Res, 243, 55-63
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Sex-specific associations between metabolic hormones, severe mental disorders and antipsychotic treatment
Psychoneuroendocrinology, 146, 105927
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Genomic Stratification of Clozapine Prescription Patterns Using Schizophrenia Polygenic Scores
Biol Psychiatry, 93 (2), 149-156
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Closing the life-cycle of normative modeling using federated hierarchical Bayesian regression
PLoS One, 17 (12), e0278776
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Mapping Normative Trajectories of Cognitive Function and Its Relation to Psychopathology Symptoms and Genetic Risk in Youth
Biol Psychiatry Glob Open Sci, 3 (2), 255-263
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Study protocol for "MDMA-assisted therapy as a treatment for major depressive disorder: A proof of principle study"
Front Psychiatry, 13, 954388
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Metabolite Profiling of Clozapine in Patients Switching Versus Maintaining Treatment: A Retrospective Pilot Study
J Clin Psychopharmacol, 42 (5), 470-474
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Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease
JAMA Neurol, 79 (7), 652-663
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Impact of NFIB and CYP1A variants on clozapine serum concentration-A retrospective naturalistic cohort study on 526 patients with known smoking habits
Clin Transl Sci, 16 (1), 62-72
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Deep neural networks learn general and clinically relevant representations of the ageing brain
Neuroimage, 256, 119210
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Generalization of cortical MOSTest genome-wide associations within and across samples
Neuroimage, 263, 119632
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Functional connectivity directionality between large-scale resting-state networks across typical and non-typical trajectories in children and adolescence
PLoS One, 17 (12), e0276221
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An epigenetic association analysis of childhood trauma in psychosis reveals possible overlap with methylation changes associated with PTSD
Transl Psychiatry, 12 (1), 177
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Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study
Lancet Public Health, 7 (5), e406-e416
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Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases
Science, 375 (6580), 522-528
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Strategies and foundations for scientific discovery in longitudinal studies of bipolar disorder
Bipolar Disord, 24 (5), 499-508
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Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations
J Alzheimers Dis, 88 (4), 1533-1544
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Negative Symptom Domains Are Associated With Verbal Learning in Adolescents With Early Onset Psychosis
Front Psychiatry, 12, 825681
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A comparison of intracranial volume estimation methods and their cross-sectional and longitudinal associations with age
Hum Brain Mapp, 43 (15), 4620-4639
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Parental socioeconomic status is linked to cortical microstructure and language abilities in children and adolescents
Dev Cogn Neurosci, 56, 101132
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Phenotype-informed polygenic risk scores are associated with worse outcome in individuals at risk of Alzheimer's disease
Alzheimers Dement (Amst), 14 (1), e12350
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Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia
JAMA Psychiatry, 79 (3), 260-269
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Multiscale neural gradients reflect transdiagnostic effects of major psychiatric conditions on cortical morphology
Commun Biol, 5 (1), 1024
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Virtual Ontogeny of Cortical Growth Preceding Mental Illness
Biol Psychiatry, 92 (4), 299-313
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Computational Modeling of the n-Back Task in the ABCD Study: Associations of Drift Diffusion Model Parameters to Polygenic Scores of Mental Disorders and Cardiometabolic Diseases
Biol Psychiatry Cogn Neurosci Neuroimaging, 8 (3), 290-299
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Genetic nurture versus genetic transmission of risk for ADHD traits in the Norwegian Mother, Father and Child Cohort Study
Mol Psychiatry, 28 (4), 1731-1738
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The co-occurrence of motor and language impairments in children evaluated for autism spectrum disorder. An explorative study from Norway
Res Dev Disabil, 127, 104256
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Quality of clinical management of cardiometabolic risk factors in patients with severe mental illness in a specialist mental health care setting
Nord J Psychiatry, 76 (8), 602-609
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Oxytocin receptor expression patterns in the human brain across development
Neuropsychopharmacology, 47 (8), 1550-1560
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Clinical and cortical similarities identified between bipolar disorder I and schizophrenia: A multivariate approach
Front Hum Neurosci, 16, 1001692
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Cardiovascular disease risk in people with severe mental disorders: an update and call for action
Curr Opin Psychiatry, 35 (4), 277-284
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Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Ann Rheum Dis, 81 (8), 1085-1095
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Theory of mind in schizophrenia: a comparison of subgroups with low and high IQ
Nord J Psychiatry, 77 (4), 329-335
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Associations between abdominal adipose tissue, reproductive span, and brain characteristics in post-menopausal women
Neuroimage Clin, 36, 103239
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Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Biol Psychiatry, 93 (2), 187-196
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Clinical predictors of antipsychotic treatment resistance: Development and internal validation of a prognostic prediction model by the STRATA-G consortium
Schizophr Res, 250, 1-9
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Schizophrenia: genetic insights with clinical potential
Nat Rev Neurol, 18 (3), 129-130
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Borderline personality disorder and the big five: molecular genetic analyses indicate shared genetic architecture with neuroticism and openness
Transl Psychiatry, 12 (1), 153
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Sex- and age-specific associations between cardiometabolic risk and white matter brain age in the UK Biobank cohort
Hum Brain Mapp, 43 (12), 3759-3774
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Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
Mol Psychiatry, 28 (3), 1284-1292
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The Relationship of Maternal Gestational Mass Spectrometry-Derived Metabolites with Offspring Congenital Heart Disease: Results from Multivariable and Mendelian Randomization Analyses
J Cardiovasc Dev Dis, 9 (8)
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The age of violence: Mapping brain age in psychosis and psychopathy
Neuroimage Clin, 36, 103181
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Shared genetic loci between depression and cardiometabolic traits
PLoS Genet, 18 (5), e1010161
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Sex as a Moderator Between Parent Ratings of Executive Dysfunction and Social Difficulties in Children and Adolescents with Autism Spectrum Disorder
J Autism Dev Disord, 53 (10), 3847-3859
DOI 10.1007/s10803-022-05629-5, PubMed 35838825
Modeling assortative mating and genetic similarities between partners, siblings, and in-laws
Nat Commun, 13 (1), 1108
DOI 10.1038/s41467-022-28774-y, PubMed 35233010
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Nature, 604 (7906), 502-508
DOI 10.1038/s41586-022-04434-5, PubMed 35396580
Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations
Int J Epidemiol, 51 (3), e108-e122
DOI 10.1093/ije/dyab234, PubMed 35020900
Editorial: Cross-disorder Genetics in Neuropsychiatry
Front Neurosci, 16, 826300
DOI 10.3389/fnins.2022.826300, PubMed 35221906
The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
Commun Biol, 5 (1), 1271
DOI 10.1038/s42003-022-04237-4, PubMed 36402844
Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology
Biol Psychiatry, 92 (4), 291-298
DOI 10.1016/j.biopsych.2021.12.007, PubMed 35164939
Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis
Transl Psychiatry, 12 (1), 38
DOI 10.1038/s41398-022-01811-6, PubMed 35082268
Limited association between infections, autoimmune disease and genetic risk and immune activation in severe mental disorders
Prog Neuropsychopharmacol Biol Psychiatry, 116, 110511
DOI 10.1016/j.pnpbp.2022.110511, PubMed 35063598
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 54 (7), 1062
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Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex
Nat Commun, 13 (1), 7945
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The oxytocin signalling gene pathway contributes to the association between loneliness and cardiometabolic health
Psychoneuroendocrinology, 144, 105875
DOI 10.1016/j.psyneuen.2022.105875, PubMed 35939863
Retrospectively assessed childhood trauma experiences are associated with illness severity in mental disorders adjusted for symptom state
Psychiatry Res, 320, 115045
DOI 10.1016/j.psychres.2022.115045, PubMed 36621206
Publications 2021
Longitudinal Structural Brain Changes in Bipolar Disorder: A Multicenter Neuroimaging Study of 1232 Individuals by the ENIGMA Bipolar Disorder Working Group
Biol Psychiatry, 91 (6), 582-592
DOI 10.1016/j.biopsych.2021.09.008, PubMed 34809987
Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia
Brain Behav Immun, 94, 235-244
DOI 10.1016/j.bbi.2021.01.037, PubMed 33571628
Cytomegalovirus infection associated with smaller dentate gyrus in men with severe mental illness
Brain Behav Immun, 96, 54-62
DOI 10.1016/j.bbi.2021.05.009, PubMed 34010712
Lower plasma total tau in adolescent psychosis: Involvement of the orbitofrontal cortex
J Psychiatr Res, 144, 255-261
DOI 10.1016/j.jpsychires.2021.10.031, PubMed 34700214
Cytomegalovirus infection and IQ in patients with severe mental illness and healthy individuals
Psychiatry Res, 300, 113929
DOI 10.1016/j.psychres.2021.113929, PubMed 33866186
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
Psychol Med, 53 (4), 1479-1488
DOI 10.1017/S0033291721003056, PubMed 35387700
Risk and protective factors for mental disorders beyond genetics: an evidence-based atlas
World Psychiatry, 20 (3), 417-436
DOI 10.1002/wps.20894, PubMed 34505386
Early manifestations of genetic risk for neurodevelopmental disorders
J Child Psychol Psychiatry, 63 (7), 810-819
DOI 10.1111/jcpp.13528, PubMed 34605010
Genetic loci shared between major depression and intelligence with mixed directions of effect
Nat Hum Behav, 5 (6), 795-801
DOI 10.1038/s41562-020-01031-2, PubMed 33462475
In Vivo Amygdala Nuclei Volumes in Schizophrenia and Bipolar Disorders
Schizophr Bull, 47 (5), 1431-1441
DOI 10.1093/schbul/sbaa192, PubMed 33479754
Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder
Int J Bipolar Disord, 9 (1), 26
DOI 10.1186/s40345-021-00231-7, PubMed 34467430
Cardiometabolic risk factors associated with brain age and accelerate brain ageing
Hum Brain Mapp, 43 (2), 700-720
DOI 10.1002/hbm.25680, PubMed 34626047
Associations between amygdala nuclei volumes, psychosis, psychopathy, and violent offending
Psychiatry Res Neuroimaging, 319, 111416
DOI 10.1016/j.pscychresns.2021.111416, PubMed 34847406
Exploring low grade inflammation by soluble urokinase plasminogen activator receptor levels in schizophrenia: a sex-dependent association with depressive symptoms
BMC Psychiatry, 21 (1), 527
DOI 10.1186/s12888-021-03522-6, PubMed 34702245
Elevated levels of soluble urokinase plasminogen activator receptor as a low-grade inflammation marker in schizophrenia: A case-control study
Schizophr Res, 228, 190-192
DOI 10.1016/j.schres.2020.11.051, PubMed 33450603
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J Affect Disord, 295, 1032-1039
DOI 10.1016/j.jad.2021.08.135, PubMed 34706411
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Biol Psychiatry, 91 (1), 102-117
DOI 10.1016/j.biopsych.2021.02.972, PubMed 34099189
Sparse deep neural networks on imaging genetics for schizophrenia case-control classification
Hum Brain Mapp, 42 (8), 2556-2568
DOI 10.1002/hbm.25387, PubMed 33724588
Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness
JAMA Psychiatry, 78 (9), 1020-1030
DOI 10.1001/jamapsychiatry.2021.1435, PubMed 34160554
Prominent health problems, socioeconomic deprivation, and higher brain age in lonely and isolated individuals: A population-based study
Behav Brain Res, 414, 113510
DOI 10.1016/j.bbr.2021.113510, PubMed 34358570
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
Nat Commun, 12 (1), 3417
DOI 10.1038/s41467-021-22491-8, PubMed 34099642
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease
Mol Psychiatry, 26 (10), 5797-5811
DOI 10.1038/s41380-021-01152-8, PubMed 34112972
Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years
Hum Brain Mapp, 43 (1), 452-469
DOI 10.1002/hbm.25320, PubMed 33570244
Associations between depression and cardiometabolic health: A 27-year longitudinal study
Psychol Med, 52 (14), 3007-3017
DOI 10.1017/S003329172000505X, PubMed 33431106
The genetic architecture of the human thalamus and its overlap with ten common brain disorders
Nat Commun, 12 (1), 2909
DOI 10.1038/s41467-021-23175-z, PubMed 34006833
Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis
JAMA Psychiatry, 78 (7), 753-766
DOI 10.1001/jamapsychiatry.2021.0638, PubMed 33950164
Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study
Pharmacogenomics J, 21 (5), 574-585
DOI 10.1038/s41397-021-00234-8, PubMed 33824429
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years
Hum Brain Mapp, 43 (1), 431-451
DOI 10.1002/hbm.25364, PubMed 33595143
Sex-Specific Effect of Serum Lipids and Body Mass Index on Psychotic Symptoms, a Cross-Sectional Study of First-Episode Psychosis Patients
Front Psychiatry, 12, 723158
DOI 10.3389/fpsyt.2021.723158, PubMed 34744818
Population-based body-brain mapping links brain morphology with anthropometrics and body composition
Transl Psychiatry, 11 (1), 295
DOI 10.1038/s41398-021-01414-7, PubMed 34006848
A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium
Hum Brain Mapp, 43 (1), 352-372
DOI 10.1002/hbm.25625, PubMed 34498337
Genetic Liability for Schizophrenia and Childhood Psychopathology in the General Population
Schizophr Bull, 47 (4), 1179-1189
DOI 10.1093/schbul/sbaa193, PubMed 33561255
Developmental milestones in early childhood and genetic liability to neurodevelopmental disorders
Psychol Med, 53 (5), 1750-1758
DOI 10.1017/S0033291721003330, PubMed 37310338
Interplay between the Genetics of Personality Traits, severe Psychiatric Disorders, and COVID-19 Host Genetics in the Susceptibility to SARS-CoV-2 Infection - ADDENDUM
BJPsych Open, 7 (6), e206
DOI 10.1192/bjo.2021.1037, PubMed 34789355
Interplay between the genetics of personality traits, severe psychiatric disorders and COVID-19 host genetics in the susceptibility to SARS-CoV-2 infection
BJPsych Open, 7 (6), e188
DOI 10.1192/bjo.2021.1030, PubMed 34659794
Aberrant default mode connectivity in adolescents with early-onset psychosis: A resting state fMRI study
Neuroimage Clin, 33, 102881
DOI 10.1016/j.nicl.2021.102881, PubMed 34883402
Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking
Transl Psychiatry, 11 (1), 466
DOI 10.1038/s41398-021-01576-4, PubMed 34497263
The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity
Genetics, 217 (3)
DOI 10.1093/genetics/iyaa046, PubMed 33789345
Erratum to: The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity
Genetics, 218 (2)
DOI 10.1093/genetics/iyab064, PubMed 34167151
Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
Nat Commun, 12 (1), 1236
DOI 10.1038/s41467-021-21287-0, PubMed 33623038
Common genetic and clinical risk factors: association with fatal prostate cancer in the Cohort of Swedish Men
Prostate Cancer Prostatic Dis, 24 (3), 845-851
DOI 10.1038/s41391-021-00341-4, PubMed 33723363
Maternal and offspring genetic risk score analyses of fetal alcohol exposure and attention-deficit hyperactivity disorder risk in offspring
Alcohol Clin Exp Res, 45 (10), 2090-2102
DOI 10.1111/acer.14692, PubMed 34486127
Multivariate alterations in insula - Medial prefrontal cortex linked to genetics in 12q24 in schizophrenia
Psychiatry Res, 306, 114237
DOI 10.1016/j.psychres.2021.114237, PubMed 34655926
Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
Eur J Hum Genet, 30 (10), 1138-1146
DOI 10.1038/s41431-021-00966-y, PubMed 34776508
Characterisation of age and polarity at onset in bipolar disorder
Br J Psychiatry, 219 (6), 659-669
DOI 10.1192/bjp.2021.102, PubMed 35048876
Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer
Prostate Cancer Prostatic Dis, 24 (2), 532-541
DOI 10.1038/s41391-020-00311-2, PubMed 33420416
Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24
Prostate Cancer Prostatic Dis, 25 (2), 229-237
DOI 10.1038/s41391-021-00403-7, PubMed 34127801
DSM-5 and ICD-11 criteria for bipolar disorder: Implications for the prevalence of bipolar disorder and validity of the diagnosis - A narrative review from the ECNP bipolar disorders network
Eur Neuropsychopharmacol, 47, 54-61
DOI 10.1016/j.euroneuro.2021.01.097, PubMed 33541809
Dose-dependent transcriptional effects of lithium and adverse effect burden in a psychiatric cohort
Prog Neuropsychopharmacol Biol Psychiatry, 112, 110408
DOI 10.1016/j.pnpbp.2021.110408, PubMed 34320404
Ketamine for depression - evidence and proposals for practice
Tidsskr Nor Laegeforen, 141
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[Not Available]
Tidsskr Nor Laegeforen, 141
DOI 10.4045/tidsskr.21.0760, PubMed 34758606
Absolute and Dose-Adjusted Serum Concentrations of Clozapine in Patients Switching vs. Maintaining Treatment: An Observational Study of 1979 Patients
CNS Drugs, 35 (9), 999-1008
DOI 10.1007/s40263-021-00847-4, PubMed 34417726
Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics
Neuropsychopharmacology, 46 (10), 1788-1801
DOI 10.1038/s41386-021-01023-4, PubMed 34035472
The association between bullying and eating disorders: A case-control study
Int J Eat Disord, 54 (8), 1405-1414
DOI 10.1002/eat.23522, PubMed 33942329
Stressful life events among individuals with a history of eating disorders: a case-control comparison
BMC Psychiatry, 21 (1), 501
DOI 10.1186/s12888-021-03499-2, PubMed 34645394
Clinical predictors of non-response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study
Bipolar Disord, 23 (8), 821-831
DOI 10.1111/bdi.13078, PubMed 33797828
Brain age prediction using fMRI network coupling in youths and associations with psychiatric symptoms
Neuroimage Clin, 33, 102921
DOI 10.1016/j.nicl.2021.102921, PubMed 34959052
Childhood trauma and cardiometabolic risk in severe mental disorders: The mediating role of cognitive control
Eur Psychiatry, 64 (1), e24
DOI 10.1192/j.eurpsy.2021.14, PubMed 33775258
Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information
Biol Psychiatry, 91 (7), 626-636
DOI 10.1016/j.biopsych.2021.09.020, PubMed 34865855
Corrigendum to "Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action [European Neuropsychopharmacology (2020) 36, 121-136]"
Eur Neuropsychopharmacol, 44, 121-122
DOI 10.1016/j.euroneuro.2021.01.001, PubMed 33495109
The genetic structure of Norway
Eur J Hum Genet, 29 (11), 1710-1718
DOI 10.1038/s41431-021-00899-6, PubMed 34002043
Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness-ENIGMA study in 2436 individuals
Bipolar Disord, 24 (5), 509-520
DOI 10.1111/bdi.13172, PubMed 34894200
Diphtheria And Tetanus Vaccination History Is Associated With Lower Odds of COVID-19 Hospitalization
Front Immunol, 12, 749264
DOI 10.3389/fimmu.2021.749264, PubMed 34691063
Genetic Overlap Between Alzheimer's Disease and Depression Mapped Onto the Brain
Front Neurosci, 15, 653130
DOI 10.3389/fnins.2021.653130, PubMed 34290577
A review of systems biology research of anxiety disorders
Braz J Psychiatry, 43 (4), 414-423
DOI 10.1590/1516-4446-2020-1090, PubMed 33053074
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Nat Genet, 53 (6), 817-829
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Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Biol Psychiatry, 91 (3), 313-327
DOI 10.1016/j.biopsych.2021.05.029, PubMed 34861974
Multisite reproducibility and test-retest reliability of the T1w/T2w-ratio: A comparison of processing methods
Neuroimage, 245, 118709
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New insights into the dynamic development of the cerebral cortex in childhood and adolescence: Integrating macro- and microstructural MRI findings
Prog Neurobiol, 204, 102109
DOI 10.1016/j.pneurobio.2021.102109, PubMed 34147583
Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes
Biol Psychiatry, 90 (9), 621-631
DOI 10.1016/j.biopsych.2021.07.007, PubMed 34482950
Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank
Psychol Med, 52 (15), 1-11 (in press)
DOI 10.1017/S0033291721000179, PubMed 33653435
Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders
Mol Psychiatry, 26 (11), 6789-6805
DOI 10.1038/s41380-021-01164-4, PubMed 34075196
Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium
J Psychiatr Res, 137, 215-224
DOI 10.1016/j.jpsychires.2021.02.027, PubMed 33691233
Genetic Stratification of Age-Dependent Parkinson's Disease Risk by Polygenic Hazard Score
Mov Disord, 37 (1), 62-69
DOI 10.1002/mds.28808, PubMed 34612543
Identification of pleiotropy at the gene level between psychiatric disorders and related traits
Transl Psychiatry, 11 (1), 410
DOI 10.1038/s41398-021-01530-4, PubMed 34326310
All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors
Front Cell Neurosci, 15, 671549
DOI 10.3389/fncel.2021.671549, PubMed 34122014
Structural and Pragmatic Language Impairments in Children Evaluated for Autism Spectrum Disorder (ASD)
J Autism Dev Disord, 53 (2), 701-719
DOI 10.1007/s10803-020-04853-1, PubMed 33515169
Outcomes associated with different vaccines in individuals with bipolar disorder and impact on the current COVID-19 pandemic- a systematic review
Eur Neuropsychopharmacol, 54, 90-99
DOI 10.1016/j.euroneuro.2021.09.001, PubMed 34607722
Adiponectin Is Related to Cardiovascular Risk in Severe Mental Illness Independent of Antipsychotic Treatment
Front Psychiatry, 12, 623192
DOI 10.3389/fpsyt.2021.623192, PubMed 34122163
Phenotypically independent profiles relevant to mental health are genetically correlated
Transl Psychiatry, 11 (1), 202
DOI 10.1038/s41398-021-01313-x, PubMed 33795632
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
Transl Psychiatry, 11 (1), 407
DOI 10.1038/s41398-021-01527-z, PubMed 34301917
Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
Transl Psychiatry, 11 (1), 3
DOI 10.1038/s41398-020-01142-4, PubMed 33414458
Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology
Neuroimage, 244, 118603
DOI 10.1016/j.neuroimage.2021.118603, PubMed 34560273
Neuropsychiatric symptoms and brain morphology in patients with mild cognitive impairment and Alzheimer's disease with dementia
Int Psychogeriatr, 33 (11), 1217-1228
DOI 10.1017/S1041610221000934, PubMed 34399870
Polygenic risk scores in psychiatry - Large potential but still limited clinical utility
Eur Neuropsychopharmacol, 51, 68-70
DOI 10.1016/j.euroneuro.2021.05.007, PubMed 34091254
Cognitive impairment profile in adolescent early-onset psychosis using the MATRICS Battery: Age and sex effects
Neuropsychology, 35 (3), 300-309
DOI 10.1037/neu0000723, PubMed 33970663
Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity
Brain Behav, 11 (8), e02188
DOI 10.1002/brb3.2188, PubMed 34291596
Examining Individual and Synergistic Contributions of PTSD and Genetics to Blood Pressure: A Trans-Ethnic Meta-Analysis
Front Neurosci, 15, 678503
DOI 10.3389/fnins.2021.678503, PubMed 34248484
A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia
Transl Psychiatry, 11 (1), 554
DOI 10.1038/s41398-021-01681-4, PubMed 34716291
Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs
Hum Brain Mapp, 43 (1), 300-328
DOI 10.1002/hbm.25354, PubMed 33615640
1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans
Transl Psychiatry, 11 (1), 182
DOI 10.1038/s41398-021-01213-0, PubMed 33753722
ENIGMA-Sleep: Challenges, opportunities, and the road map
J Sleep Res, 30 (6), e13347
DOI 10.1111/jsr.13347, PubMed 33913199
Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors
Transl Psychiatry, 11 (1), 368
DOI 10.1038/s41398-021-01466-9, PubMed 34226488
Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder
Schizophr Bull, 47 (6), 1751-1760
DOI 10.1093/schbul/sbab049, PubMed 33963856
The genetic architecture of human cortical folding
Sci Adv, 7 (51), eabj9446
DOI 10.1126/sciadv.abj9446, PubMed 34910505
The factor structure of social cognition in schizophrenia: Weak evidence for separable domains
Schizophr Res Cogn, 26, 100208
DOI 10.1016/j.scog.2021.100208, PubMed 34430229
Similar Genetic Architecture of Alzheimer's Disease and Differential APOE Effect Between Sexes
Front Aging Neurosci, 13, 674318
DOI 10.3389/fnagi.2021.674318, PubMed 34122051
Causal association of cognitive reserve on Alzheimer's disease with putative sex difference
Alzheimers Dement (Amst), 13 (1), e12270
DOI 10.1002/dad2.12270, PubMed 35005200
Common Genetic Variation and Age of Onset of Anorexia Nervosa
Biol Psychiatry Glob Open Sci, 2 (4), 368-378
DOI 10.1016/j.bpsgos.2021.09.001, PubMed 36324647
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 53 (9), 1276-1282
DOI 10.1038/s41588-021-00921-z, PubMed 34493870
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 53 (12), 1722
DOI 10.1038/s41588-021-00977-x, PubMed 34773122
12-year prediction of mild cognitive impairment aided by Alzheimer's brain signatures at mean age 56
Brain Commun, 3 (3), fcab167
DOI 10.1093/braincomms/fcab167, PubMed 34396116
Oxytocin-pathway polygenic scores for severe mental disorders and metabolic phenotypes in the UK Biobank
Transl Psychiatry, 11 (1), 599
DOI 10.1038/s41398-021-01725-9, PubMed 34824196
Psychometric properties of the Norwegian version of the Patient Health Questionnaire-9 (PHQ-9) in a large female sample of adults with and without eating disorders
BMC Psychiatry, 21 (1), 6
DOI 10.1186/s12888-020-03013-0, PubMed 33402149
Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci
Addiction, 117 (3), 600-610
DOI 10.1111/add.15680, PubMed 34472679
Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder
Hum Brain Mapp, 42 (8), 2546-2555
DOI 10.1002/hbm.25386, PubMed 33638594
Association of Birth Asphyxia With Regional White Matter Abnormalities Among Patients With Schizophrenia and Bipolar Disorders
JAMA Netw Open, 4 (12), e2139759
DOI 10.1001/jamanetworkopen.2021.39759, PubMed 34928356
Significant association between intracranial volume and verbal intellectual abilities in patients with schizophrenia and a history of birth asphyxia
Psychol Med, 52 (15), 1-10 (in press)
DOI 10.1017/S0033291721000489, PubMed 33750510
Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders
JAMA Psychiatry, 78 (1), 47-63
DOI 10.1001/jamapsychiatry.2020.2694, PubMed 32857118
Gut microbial biomarkers for the treatment response in first-episode, drug-naïve schizophrenia: a 24-week follow-up study
Transl Psychiatry, 11 (1), 422
DOI 10.1038/s41398-021-01531-3, PubMed 34376634
Physical activity and childhood trauma experiences in patients with schizophrenia or bipolar disorders
World J Biol Psychiatry, 22 (8), 637-645
DOI 10.1080/15622975.2021.1907707, PubMed 33779484
Publications 2020
Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
Brain Behav Immun, 87, 634-644
DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548
The effects of cognitive abilities and task demands on tonic and phasic pupil sizes
Biol Psychol, 156, 107945
DOI 10.1016/j.biopsycho.2020.107945, PubMed 32889001
Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study
JAMA Psychiatry, 77 (5), 503-512
DOI 10.1001/jamapsychiatry.2019.4188, PubMed 31913414
Exploring white matter microstructure and the impact of antipsychotics in adolescent-onset psychosis
PLoS One, 15 (5), e0233684
DOI 10.1371/journal.pone.0233684, PubMed 32470000
White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age prediction
Neuroimage, 224, 117441
DOI 10.1016/j.neuroimage.2020.117441, PubMed 33039618
Heart rate variability is associated with disease severity in psychosis spectrum disorders
Prog Neuropsychopharmacol Biol Psychiatry, 111, 110108
DOI 10.1016/j.pnpbp.2020.110108, PubMed 32946948
How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa)
BMC Med, 18 (1), 284
DOI 10.1186/s12916-020-01760-1, PubMed 33106172
What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 56-82
DOI 10.1002/hbm.25098, PubMed 32725849
Genetic control of variability in subcortical and intracranial volumes
Mol Psychiatry, 26 (8), 3876-3883
DOI 10.1038/s41380-020-0664-1, PubMed 32047264
Genome-wide association study identifies 48 common genetic variants associated with handedness
Nat Hum Behav, 5 (1), 59-70
DOI 10.1038/s41562-020-00956-y, PubMed 32989287
Intelligence, educational attainment, and brain structure in those at familial high-risk for schizophrenia or bipolar disorder
Hum Brain Mapp, 43 (1), 414-430
DOI 10.1002/hbm.25206, PubMed 33027543
Exploring the Effects of an Acute Dose of Antipsychotic Medication on Motivation-mediated BOLD Activity Using fMRI and a Perceptual Decision-making Task
Neuroscience, 440, 146-159
DOI 10.1016/j.neuroscience.2020.05.035, PubMed 32473275
Differences in course of illness between patients with bipolar II disorder with and without epileptiform discharges or other sharp activity on electroencephalograms: a cross-sectional study
BMC Psychiatry, 20 (1), 582
DOI 10.1186/s12888-020-02968-4, PubMed 33287748
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Nat Commun, 11 (1), 4016
DOI 10.1038/s41467-020-17376-1, PubMed 32782260
Polygenic scores for schizophrenia and general cognitive ability: associations with six cognitive domains, premorbid intelligence, and cognitive composite score in individuals with a psychotic disorder and in healthy controls
Transl Psychiatry, 10 (1), 416
DOI 10.1038/s41398-020-01094-9, PubMed 33257657
Sex-dependent autosomal effects on clinical progression of Alzheimer's disease
Brain, 143 (7), 2272-2280
DOI 10.1093/brain/awaa164, PubMed 32591829
Social Perception Predicts Awareness of Illness in Persons With Schizophrenia
J Nerv Ment Dis, 208 (9), 701-705
DOI 10.1097/NMD.0000000000001185, PubMed 32433201
The genetic architecture of the human cerebral cortex
Science, 367 (6484)
DOI 10.1126/science.aay6690, PubMed 32193296
Intracranial and subcortical volumes in adolescents with early-onset psychosis: A multisite mega-analysis from the ENIGMA consortium
Hum Brain Mapp, 43 (1), 373-384
DOI 10.1002/hbm.25212, PubMed 33017498
Computationally efficient familywise error rate control in genome-wide association studies using score tests for generalized linear models
Scand. J. Stat., 47 (4), 1090-1113
DOI 10.1111/sjos.12451
Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group
Mol Psychiatry, 26 (9), 5124-5139
DOI 10.1038/s41380-020-0754-0, PubMed 32424236
In vivo hippocampal subfield volumes in bipolar disorder-A mega-analysis from The Enhancing Neuro Imaging Genetics through Meta-Analysis Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 385-398
DOI 10.1002/hbm.25249, PubMed 33073925
Disentangling the relationship between cholesterol, aggression, and impulsivity in severe mental disorders
Brain Behav, 10 (9), e01751
DOI 10.1002/brb3.1751, PubMed 32681586
Childhood trauma is associated with poorer social functioning in severe mental disorders both during an active illness phase and in remission
Schizophr Res, 243, 241-246
DOI 10.1016/j.schres.2020.03.015, PubMed 32222348
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults
Nat Commun, 11 (1), 4796
DOI 10.1038/s41467-020-18367-y, PubMed 32963231
Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model
PLoS Genet, 16 (5), e1008612
DOI 10.1371/journal.pgen.1008612, PubMed 32427991
The Relationship Between White Matter Microstructure and General Cognitive Ability in Patients With Schizophrenia and Healthy Participants in the ENIGMA Consortium
Am J Psychiatry, 177 (6), 537-547
DOI 10.1176/appi.ajp.2019.19030225, PubMed 32212855
Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia: A comparison among participants between 2 and 53 years
FASEB J, 34 (6), 8114-8124
DOI 10.1096/fj.201900855RRR, PubMed 32323402
A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data
Cancer Epidemiol Biomarkers Prev, 29 (9), 1731-1738
DOI 10.1158/1055-9965.EPI-19-1527, PubMed 32581112
Age dependence of modern clinical risk groups for localized prostate cancer-A population-based study
Cancer, 126 (8), 1691-1699
DOI 10.1002/cncr.32702, PubMed 31899813
Differences in the Presentation and Progression of Parkinson's Disease by Sex
Mov Disord, 36 (1), 106-117
DOI 10.1002/mds.28312, PubMed 33002231
Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet, 52 (3), 354
DOI 10.1038/s41588-019-0573-x, PubMed 32029921
The effect of sample size on polygenic hazard models for prostate cancer
Eur J Hum Genet, 28 (10), 1467-1475
DOI 10.1038/s41431-020-0664-2, PubMed 32514134
African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer
Int J Cancer, 148 (1), 99-105
DOI 10.1002/ijc.33282, PubMed 32930425
Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 23 (2), 295
DOI 10.1038/s41593-019-0553-6, PubMed 31848485
ENIGMA-DTI: Translating reproducible white matter deficits into personalized vulnerability metrics in cross-diagnostic psychiatric research
Hum Brain Mapp, 43 (1), 194-206
DOI 10.1002/hbm.24998, PubMed 32301246
Cortical thickness and resting-state cardiac function across the lifespan: A cross-sectional pooled mega-analysis
Psychophysiology, 58 (7), e13688
DOI 10.1111/psyp.13688, PubMed 33037836
Undetectable or subtherapeutic serum levels of antipsychotic drugs preceding switch to clozapine
NPJ Schizophr, 6 (1), 17
DOI 10.1038/s41537-020-0107-7, PubMed 32681055
Brain structural correlates of insomnia severity in 1053 individuals with major depressive disorder: results from the ENIGMA MDD Working Group
Transl Psychiatry, 10 (1), 425
DOI 10.1038/s41398-020-01109-5, PubMed 33293520
Pleiotropy of polygenic factors associated with focal and generalized epilepsy in the general population
PLoS One, 15 (4), e0232292
DOI 10.1371/journal.pone.0232292, PubMed 32343744
Differences in directed functional brain connectivity related to age, sex and mental health
Hum Brain Mapp, 41 (15), 4173-4186
DOI 10.1002/hbm.25116, PubMed 32613721
Associations between schizophrenia polygenic risk and apathy in schizophrenia spectrum disorders and healthy controls
Acta Psychiatr Scand, 141 (5), 452-464
DOI 10.1111/acps.13167, PubMed 32091622
Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action
Eur Neuropsychopharmacol, 36, 121-136
DOI 10.1016/j.euroneuro.2020.05.006, PubMed 32536571
Interleukin 18 (IL-18) and its binding protein (IL-18BP) are increased in patients with epilepsy suggesting low-grade systemic inflammation
Seizure, 80, 221-225
DOI 10.1016/j.seizure.2020.05.018, PubMed 32659652
Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies
Addict Biol, 26 (1), e12880
DOI 10.1111/adb.12880, PubMed 32064741
The role of norepinephrine in the pathophysiology of schizophrenia
Neurosci Biobehav Rev, 118, 298-314
DOI 10.1016/j.neubiorev.2020.07.038, PubMed 32768486
Maturation of cortical microstructure and cognitive development in childhood and adolescence: A T1w/T2w ratio MRI study
Hum Brain Mapp, 41 (16), 4676-4690
DOI 10.1002/hbm.25149, PubMed 32744409
Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents
Transl Psychiatry, 10 (1), 251
DOI 10.1038/s41398-020-00931-1, PubMed 32710012
Age of First Walking and Associations with Symptom Severity in Children with Suspected or Diagnosed Autism Spectrum Disorder
J Autism Dev Disord, 50 (9), 3216-3232
DOI 10.1007/s10803-019-04112-y, PubMed 31278523
Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
Front Psychiatry, 11, 672
DOI 10.3389/fpsyt.2020.00672, PubMed 32754070
The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia
Schizophr Bull, 46 (2), 336-344
DOI 10.1093/schbul/sbz061, PubMed 31206164
Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disorders
Hum Brain Mapp, 42 (6), 1714-1726
DOI 10.1002/hbm.25323, PubMed 33340180
Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap
Mol Psychiatry, 26 (3), 722-724
DOI 10.1038/s41380-020-00915-z, PubMed 33060817
Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR
Bioinformatics, 36 (18), 4749-4756
DOI 10.1093/bioinformatics/btaa568, PubMed 32539089
Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease
Mov Disord, 36 (2), 449-459
DOI 10.1002/mds.28338, PubMed 33107653
Nonsocial cognitive underpinnings of theory of mind in schizophrenia
Psychiatry Res, 289, 113055
DOI 10.1016/j.psychres.2020.113055, PubMed 32446008
Correction: Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Mol Psychiatry, 25 (4), 914
DOI 10.1038/s41380-019-0456-7, PubMed 31308466
The polygenic architecture of schizophrenia - rethinking pathogenesis and nosology
Nat Rev Neurol, 16 (7), 366-379
DOI 10.1038/s41582-020-0364-0, PubMed 32528109
Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci
Biol Psychiatry, 89 (3), 227-235
DOI 10.1016/j.biopsych.2020.01.026, PubMed 32201043
Negative and disorganized symptoms mediate the relationship between verbal learning and global functioning in adolescents with early-onset psychosis
Eur Child Adolesc Psychiatry, 29 (12), 1693-1703
DOI 10.1007/s00787-020-01479-7, PubMed 32036438
Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
Transl Psychiatry, 10 (1), 198
DOI 10.1038/s41398-020-00888-1, PubMed 32555152
Correction: Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
Transl Psychiatry, 10 (1), 366
DOI 10.1038/s41398-020-01061-4, PubMed 33139722
Impact of antipsychotic polypharmacy on nonadherence of oral antipsychotic drugs - A study based on blood sample analyses from 24,239 patients
Eur Neuropsychopharmacol, 37, 64-69
DOI 10.1016/j.euroneuro.2020.06.007, PubMed 32595082
Rates of complete nonadherence among atypical antipsychotic drugs: A study using blood samples from 13,217 outpatients with psychotic disorders
Schizophr Res, 228, 590-596
DOI 10.1016/j.schres.2020.11.025, PubMed 33221147
Childhood Trauma in Persons With Schizophrenia and a History of Interpersonal Violence
Front Psychiatry, 11, 383
DOI 10.3389/fpsyt.2020.00383, PubMed 32431632
Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
Front Psychiatry, 11, 642
DOI 10.3389/fpsyt.2020.00642, PubMed 32714224
Exploring neurophysiological markers of visual perspective taking: Methodological considerations
Int J Psychophysiol, 161, 1-12
DOI 10.1016/j.ijpsycho.2020.12.006, PubMed 33388368
Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
Mol Psychiatry, 25 (3), 692-695
DOI 10.1038/s41380-019-0358-8, PubMed 30705424
Insulin Resistance and Oxidative Stress: In Relation to Cognitive Function and Psychopathology in Drug-Naïve, First-Episode Drug-Free Schizophrenia
Front Psychiatry, 11, 537280
DOI 10.3389/fpsyt.2020.537280, PubMed 33329081
Hippocampal subfield and amygdala nuclei volumes in schizophrenia patients with a history of violence
Eur Arch Psychiatry Clin Neurosci, 270 (6), 771-782
DOI 10.1007/s00406-020-01098-y, PubMed 31980898
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
Transl Psychiatry, 10 (1), 100
DOI 10.1038/s41398-020-0705-1, PubMed 32198361
Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder: A Multisample Diffusion Tensor Imaging Study
Biol Psychiatry Cogn Neurosci Neuroimaging, 5 (12), 1095-1103
DOI 10.1016/j.bpsc.2020.06.014, PubMed 32859549
Experience-dependent modulation of the visual evoked potential: Testing effect sizes, retention over time, and associations with age in 415 healthy individuals
Neuroimage, 223, 117302
DOI 10.1016/j.neuroimage.2020.117302, PubMed 32828930
Quantifying the Polygenic Architecture of the Human Cerebral Cortex: Extensive Genetic Overlap between Cortical Thickness and Surface Area
Cereb Cortex, 30 (10), 5597-5603
DOI 10.1093/cercor/bhaa146, PubMed 32483632
Understanding the genetic determinants of the brain with MOSTest
Nat Commun, 11 (1), 3512
DOI 10.1038/s41467-020-17368-1, PubMed 32665545
Author Correction: Understanding the genetic determinants of the brain with MOSTest
Nat Commun, 11 (1), 4700
DOI 10.1038/s41467-020-18628-w, PubMed 32929091
Cognitive Heterogeneity across Schizophrenia and Bipolar Disorder: A Cluster Analysis of Intellectual Trajectories
J Int Neuropsychol Soc, 26 (9), 860-872
DOI 10.1017/S1355617720000442, PubMed 32423506
Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth
PLoS Genet, 16 (11), e1009163
DOI 10.1371/journal.pgen.1009163, PubMed 33227023
Author Correction: A global overview of pleiotropy and genetic architecture in complex traits
Nat Genet, 52 (3), 353
DOI 10.1038/s41588-019-0571-z, PubMed 32029922
Reduced levels of circulating adhesion molecules in adolescents with early-onset psychosis
NPJ Schizophr, 6 (1), 20
DOI 10.1038/s41537-020-00112-5, PubMed 32811840
Indicated association between polygenic risk score and treatment-resistance in a naturalistic sample of patients with schizophrenia spectrum disorders
Schizophr Res, 218, 55-62
DOI 10.1016/j.schres.2020.03.006, PubMed 32171635
Greater male than female variability in regional brain structure across the lifespan
Hum Brain Mapp, 43 (1), 470-499
DOI 10.1002/hbm.25204, PubMed 33044802
Associations of loneliness and social isolation with cardiovascular and metabolic health: a systematic review and meta-analysis protocol
Syst Rev, 9 (1), 102
DOI 10.1186/s13643-020-01369-8, PubMed 32366295
Improving the precision of intranasal oxytocin research
Nat Hum Behav, 5 (1), 9-18
DOI 10.1038/s41562-020-00996-4, PubMed 33257880
Asphyxia at birth affects brain structure in patients on the schizophrenia-bipolar disorder spectrum and healthy participants
Psychol Med, 52 (6), 1050-1059
DOI 10.1017/S0033291720002779, PubMed 32772969
Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition
JAMA Psychiatry, 77 (4), 420-430
DOI 10.1001/jamapsychiatry.2019.3779, PubMed 31665216
Childhood Trauma Is Nominally Associated With Elevated Cortisol Metabolism in Severe Mental Disorder
Front Psychiatry, 11, 391
DOI 10.3389/fpsyt.2020.00391, PubMed 32528319
Publications 2019
Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study
Neuropsychopharmacology, 45 (6), 947-955
DOI 10.1038/s41386-019-0556-8, PubMed 31652432
Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk
JAMA Psychiatry, 76 (7), 739-748
DOI 10.1001/jamapsychiatry.2019.0257, PubMed 30969333
Association between solar insolation and a history of suicide attempts in bipolar I disorder
J Psychiatr Res, 113, 1-9
DOI 10.1016/j.jpsychires.2019.03.001, PubMed 30878786
Shared Genetic Risk of Schizophrenia and Gray Matter Reduction in 6p22.1
Schizophr Bull, 45 (1), 222-232
DOI 10.1093/schbul/sby010, PubMed 29474680
Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease
Transl Psychiatry, 9 (1), 273
DOI 10.1038/s41398-019-0592-5, PubMed 31641104
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Nat Commun, 10 (1), 2068
DOI 10.1038/s41467-019-10160-w, PubMed 31043617
Population-based neuroimaging reveals traces of childbirth in the maternal brain
Proc Natl Acad Sci U S A, 116 (44), 22341-22346
DOI 10.1073/pnas.1910666116, PubMed 31615888
The Association Between Familial Risk and Brain Abnormalities Is Disease Specific: An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder
Biol Psychiatry, 86 (7), 545-556
DOI 10.1016/j.biopsych.2019.03.985, PubMed 31443932
Antipsychotic treatment and basal ganglia volumes: Exploring the role of receptor occupancy, dosage and remission status
Schizophr Res, 208, 114-123
DOI 10.1016/j.schres.2019.04.002, PubMed 31006616
Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes
Front Neurosci, 13, 220
DOI 10.3389/fnins.2019.00220, PubMed 30930738
Genetic risk for coronary heart disease alters the influence of Alzheimer's genetic risk on mild cognitive impairment
Neurobiol Aging, 84, 237.e5-237.e12
DOI 10.1016/j.neurobiolaging.2019.06.001, PubMed 31272697
Objectively Assessed Daily Steps-Not Light Intensity Physical Activity, Moderate-to-Vigorous Physical Activity and Sedentary Time-Is Associated With Cardiorespiratory Fitness in Patients With Schizophrenia
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Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individuals
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Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
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Theory of mind in schizophrenia and bipolar disorder: psychometric properties of the Norwegian version of the Hinting Task
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Association between leptin levels and severity of suicidal behaviour in schizophrenia spectrum disorders
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Identification of common genetic risk variants for autism spectrum disorder
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Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder
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The Association Between Cardiorespiratory Fitness and Cognition Appears Neither Related to Current Physical Activity Nor Mediated by Brain-Derived Neurotrophic Factor in a Sample of Outpatients With Schizophrenia
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Atypical event-related potentials revealed during the passive parts of a Go-NoGo task in autism spectrum disorder: a case-control study
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Tobacco smoking and other substance use disorders associated with recurrent suicide attempts in bipolar disorder
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The association between hippocampal subfield volumes in mild cognitive impairment and conversion to Alzheimer's disease
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Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
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Distinct structural brain circuits indicate mood and apathy profiles in bipolar disorder
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Common brain disorders are associated with heritable patterns of apparent aging of the brain
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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways
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Sleep disturbances in schizophrenia spectrum and bipolar disorders - a transdiagnostic perspective
Compr Psychiatry, 91, 6-12
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Brain Connectome Mapping of Complex Human Traits and Their Polygenic Architecture Using Machine Learning
Biol Psychiatry, 87 (8), 717-726
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Cerebellar Gray Matter Volume Is Associated With Cognitive Function and Psychopathology in Adolescence
Biol Psychiatry, 86 (1), 65-75
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GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores
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Computational Modeling of Genetic Contributions to Excitability and Neural Coding in Layer V Pyramidal Cells: Applications to Schizophrenia Pathology
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Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders
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Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors
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Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
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International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
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Roadmap for a precision-medicine initiative in the Nordic region
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Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder
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Identification of Genetic Loci Shared Between Attention-Deficit/Hyperactivity Disorder, Intelligence, and Educational Attainment
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Nat Genet, 51 (7), 1193
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Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder A Mendelian Randomization Study
JAMA Netw. Open, 2 (5), e193447
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Oxytocin pathway gene networks in the human brain
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GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
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Cardiovascular risk remains high in schizophrenia with modest improvements in bipolar disorder during past decade
Acta Psychiatr Scand, 139 (4), 348-360
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GWASinlps: non-local prior based iterative SNP selection tool for genome-wide association studies
Bioinformatics, 35 (1), 1-11
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Genetic architecture of subcortical brain structures in 38,851 individuals
Nat Genet, 51 (11), 1624-1636
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Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder
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Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative
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Perceived and experienced stigma in first-episode psychosis: A 1-year follow-up study
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Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Mol Psychiatry, 25 (4), 844-853
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The emerging pattern of shared polygenic architecture of psychiatric disorders, conceptual and methodological challenges
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Discovery of shared genomic loci using the conditional false discovery rate approach
Hum Genet, 139 (1), 85-94
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Healthy Adolescent Performance With Standardized Scoring Tables for the MATRICS Consensus Cognitive Battery: A Multisite Study
Schizophr Bull, 45 (4), 773-783
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Reduction in N-Desmethylclozapine Level Is Determined by Daily Dose But Not Serum Concentration of Valproic Acid-Indications of a Presystemic Interaction Mechanism
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Correction to: Psychiatric genetics and the structure of psychopathology
Mol Psychiatry, 24 (3), 471
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A five-year follow-up study of antioxidants, oxidative stress and polyunsaturated fatty acids in schizophrenia
Acta Neuropsychiatr, 31 (4), 202-212
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Genome-wide association study identifies 30 loci associated with bipolar disorder
Nat Genet, 51 (5), 793-803
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Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders
Psychol Med, 50 (4), 595-606
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A preliminary study of cortical morphology in schizophrenia patients with a history of violence
Psychiatry Res Neuroimaging, 288, 29-36
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Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration
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White matter microstructure in schizophrenia patients with a history of violence
Eur Arch Psychiatry Clin Neurosci, 271 (4), 623-634
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Autism spectrum disorder polygenic scores are associated with every day executive function in children admitted for clinical assessment
Autism Res, 13 (2), 207-220
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A randomized controlled trial of training of affect recognition (TAR) in schizophrenia shows lasting effects for theory of mind
Eur Arch Psychiatry Clin Neurosci, 269 (5), 611-620
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Adipokine levels are associated with insulin resistance in antipsychotics users independently of BMI
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Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations
J Affect Disord, 252, 350-357
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A global overview of pleiotropy and genetic architecture in complex traits
Nat Genet, 51 (9), 1339-1348
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Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Nat Genet, 51 (8), 1207-1214
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Lipid alterations in adolescents with early-onset psychosis may be independent of antipsychotic medication
Schizophr Res, 216, 295-301
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Increased interleukin 18 activity in adolescents with early-onset psychosis is associated with cortisol and depressive symptoms
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Population-Based Mapping of Polygenic Risk for Schizophrenia on the Human Brain: New Opportunities to Capture the Dimensional Aspects of Severe Mental Disorders
Biol Psychiatry, 86 (7), 499-501
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Obstetric complications and intelligence in patients on the schizophrenia-bipolar spectrum and healthy participants
Psychol Med, 50 (11), 1914-1922
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Mood episodes are associated with increased cortical thinning: A longitudinal study of bipolar disorder type II
Bipolar Disord, 21 (6), 525-538
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Childhood maltreatment and polygenic risk in bipolar disorders
Bipolar Disord, 22 (2), 174-181
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The relationship between physical activity, clinical and cognitive characteristics and BDNF mRNA levels in patients with severe mental disorders
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Telomere length is associated with childhood trauma in patients with severe mental disorders
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Elevated hair cortisol is associated with childhood maltreatment and cognitive impairment in schizophrenia and in bipolar disorders
Schizophr Res, 213, 65-71
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Publications 2018
Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance
Sci Rep, 8 (1), 12654
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Association of Heritable Cognitive Ability and Psychopathology With White Matter Properties in Children and Adolescents
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Recently evolved human-specific methylated regions are enriched in schizophrenia signals
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Analysis of differentially methylated regions in great apes and extinct hominids provides support for the evolutionary hypothesis of schizophrenia
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Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives
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Vitamin D levels, brain volume, and genetic architecture in patients with psychosis
PLoS One, 13 (8), e0200250
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Cross-tissue eQTL enrichment of associations in schizophrenia
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CXCR4 involvement in neurodegenerative diseases
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Analysis of shared heritability in common disorders of the brain
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Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
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Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
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Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease
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Effects of autozygosity and schizophrenia polygenic risk on cognitive and brain developmental trajectories
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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
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Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
Nat Genet, 51 (1), 63-75
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An association between YKL-40 and type 2 diabetes in psychotic disorders
Acta Psychiatr Scand, 139 (1), 37-45
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Clinical characteristics of patients with bipolar disorder and premorbid traumatic brain injury: a cross-sectional study
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Reliability and validity of the self-report version of the apathy evaluation scale in first-episode Psychosis: Concordance with the clinical version at baseline and 12 months follow-up
Psychiatry Res, 267, 140-147
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Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: a proof of concept for multivariate endophenotypes
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Beyond heritability: improving discoverability in imaging genetics
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Association between olanzapine treatment and brain cortical thickness and gray/white matter contrast is moderated by cholesterol in psychotic disorders
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Gjestad et al. reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker
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Association between serum lipid levels, osteoprotegerin and depressive symptomatology in psychotic disorders
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Hippocampus volume reduction in psychosis spectrum could be ameliorated by vitamin D
Schizophr Res, 199, 433-435
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Vitamin D, Folate and the Intracranial Volume in Schizophrenia and Bipolar Disorder and Healthy Controls
Sci Rep, 8 (1), 10817
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Cardio-respiratory fitness is associated with a verbal factor across cognitive domains in schizophrenia
Schizophr Res, 206, 157-162
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Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder
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Attenuated Notch signaling in schizophrenia and bipolar disorder
Sci Rep, 8 (1), 5349
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Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
Transl Psychiatry, 8 (1), 210
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Widespread white matter changes in post-H1N1 patients with narcolepsy type 1 and first-degree relatives
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Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum
JAMA Neurol, 75 (7), 860-875
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Stability of the Brain Functional Connectome Fingerprint in Individuals With Schizophrenia
JAMA Psychiatry, 75 (7), 749-751
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Combining Polygenic Hazard Score With Volumetric MRI and Cognitive Measures Improves Prediction of Progression From Mild Cognitive Impairment to Alzheimer's Disease
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Revisiting Antipsychotic Drug Actions Through Gene Networks Associated With Schizophrenia
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Key Brain Network Nodes Show Differential Cognitive Relevance and Developmental Trajectories during Childhood and Adolescence
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In Vivo Two-Photon Voltage Imaging with Sulfonated Rhodamine Dyes
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Psychedelic drugs in the treatment of anxiety, depression and addiction
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Psychedelic drugs in the treatment of anxiety, depression and addiction
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Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)
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A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework
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A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia
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Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex
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Use of an Alzheimer's disease polygenic risk score to identify mild cognitive impairment in adults in their 50s
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Cortical thickness abnormalities in bipolar disorder patients with a lifetime history of auditory hallucinations
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Probing Brain Developmental Patterns of Myelination and Associations With Psychopathology in Youths Using Gray/White Matter Contrast
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Using structural MRI to identify bipolar disorders - 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group
Mol Psychiatry, 25 (9), 2130-2143
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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
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Evidence for intranasal oxytocin delivery to the brain: recent advances and future perspectives
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The Promise of Intranasal Esketamine as a Novel and Effective Antidepressant
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Low-dose intranasal oxytocin delivered with Breath Powered device modulates pupil diameter and amygdala activity: a randomized controlled pupillometry and fMRI study
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Saliva oxytocin measures do not reflect peripheral plasma concentrations after intranasal oxytocin administration in men
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Assessing distinct patterns of cognitive aging using tissue-specific brain age prediction based on diffusion tensor imaging and brain morphometry
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Cardiometabolic risk factors, physical activity and psychiatric status in patients in long-term psychiatric inpatient departments
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Using motivational techniques to reduce cardiometabolic risk factors in long term psychiatric inpatients: a naturalistic interventional study
BMC Psychiatry, 18 (1), 255
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Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Nat Genet, 50 (7), 912-919
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Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts
BMJ, 360, j5757
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Thalamo-cortical functional connectivity in schizophrenia and bipolar disorder
Brain Imaging Behav, 12 (3), 640-652
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How can genetics help understand the relationship between cognitive dysfunction and schizophrenia?
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Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms
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Psychiatric genetics and the structure of psychopathology
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Restriction spectrum imaging of white matter and its relation to neurological disability in multiple sclerosis
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Enrichment of genetic markers of recent human evolution in educational and cognitive traits
Sci Rep, 8 (1), 12585
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Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes
Sci Rep, 8 (1), 6915
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Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
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Deep 2-photon imaging and artifact-free optogenetics through transparent graphene microelectrode arrays
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Metacognitive Aspects of Executive Function Are Highly Associated with Social Functioning on Parent-Rated Measures in Children with Autism Spectrum Disorder
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White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging
Sci Rep, 8 (1), 14129
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Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes
Mol Psychiatry, 25 (11), 3053-3065
DOI 10.1038/s41380-018-0262-7, PubMed 30279459
Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium
Biol Psychiatry, 84 (9), 644-654
DOI 10.1016/j.biopsych.2018.04.023, PubMed 29960671
Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?
Biol Psychiatry, 85 (7), e35-e39
DOI 10.1016/j.biopsych.2018.10.003, PubMed 30470561
Emotion perception, non-social cognition and symptoms as predictors of theory of mind in schizophrenia
Compr Psychiatry, 85, 1-7
DOI 10.1016/j.comppsych.2018.05.002, PubMed 29906670
Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication
J Psychiatr Res, 106, 74-81
DOI 10.1016/j.jpsychires.2018.09.014, PubMed 30292780
Response: Are thyroid abnormalities only related to antipsychotic treatment in patients with severe mental disorders?
J Psychiatr Res, 117, 150
DOI 10.1016/j.jpsychires.2018.11.012, PubMed 30454945
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume
Nat Commun, 9 (1), 3945
DOI 10.1038/s41467-018-06234-w, PubMed 30258056
Meta-analysis of Alzheimer's disease on 9,751 samples from Norway and IGAP study identifies four risk loci
Sci Rep, 8 (1), 18088
DOI 10.1038/s41598-018-36429-6, PubMed 30591712
Mapping the Heterogeneous Phenotype of Schizophrenia and Bipolar Disorder Using Normative Models
JAMA Psychiatry, 75 (11), 1146-1155
DOI 10.1001/jamapsychiatry.2018.2467, PubMed 30304337
Longitudinal and cross-sectional investigations of long-term potentiation-like cortical plasticity in bipolar disorder type II and healthy individuals
Transl Psychiatry, 8 (1), 103
DOI 10.1038/s41398-018-0151-5, PubMed 29795193
Identification of shared genetic variants between schizophrenia and lung cancer
Sci Rep, 8 (1), 674
DOI 10.1038/s41598-017-16481-4, PubMed 29330379
Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders
Schizophr Res, 205, 45-50
DOI 10.1016/j.schres.2018.08.007, PubMed 30126813
Publications 2017
Diabetes and Schizophrenia-New Findings for an Old Puzzle
Am J Psychiatry, 174 (7), 616-617
DOI 10.1176/appi.ajp.2017.17040409, PubMed 28669214
eHealth provides a novel opportunity to exploit the advantages of the Nordic countries in psychiatric genetic research, building on the public health care system, biobanks, and registries
Am J Med Genet B Neuropsychiatr Genet, 177 (7), 625-629
DOI 10.1002/ajmg.b.32561, PubMed 28686333
Solar insolation in springtime influences age of onset of bipolar I disorder
Acta Psychiatr Scand, 136 (6), 571-582
DOI 10.1111/acps.12772, PubMed 28722128
Right unilateral electroconvulsive therapy does not cause more cognitive impairment than pharmacologic treatment in treatment-resistant bipolar depression: A 6-month randomized controlled trial follow-up study
Bipolar Disord, 20 (6), 531-538
DOI 10.1111/bdi.12594, PubMed 29267990
Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure
Sci Rep, 7 (1), 15736
DOI 10.1038/s41598-017-15705-x, PubMed 29147026
Genetic factors influencing prostate cancer risk in Norwegian men
Prostate, 78 (3), 186-192
DOI 10.1002/pros.23453, PubMed 29181843
Childhood Trauma and Minimization/Denial in People with and without a Severe Mental Disorder
Front Psychol, 8, 1276
DOI 10.3389/fpsyg.2017.01276, PubMed 28883800
Disrupted global metastability and static and dynamic brain connectivity across individuals in the Alzheimer's disease continuum
Sci Rep, 7, 40268
DOI 10.1038/srep40268, PubMed 28074926
Neurocognitive functioning, clinical course and functional outcome in first-treatment bipolar I disorder patients with and without clinical relapse: A 1-year follow-up study
Bipolar Disord, 20 (3), 228-237
DOI 10.1111/bdi.12569, PubMed 29121444
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score
PLoS Med, 14 (3), e1002258
DOI 10.1371/journal.pmed.1002258, PubMed 28323831
Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia
Mol Psychiatry, 22 (6), 792-801
DOI 10.1038/mp.2017.33, PubMed 28348379
Dissociable diffusion MRI patterns of white matter microstructure and connectivity in Alzheimer's disease spectrum
Sci Rep, 7, 45131
DOI 10.1038/srep45131, PubMed 28338052
Distinguishing early and late brain aging from the Alzheimer's disease spectrum: consistent morphological patterns across independent samples
Neuroimage, 158, 282-295
DOI 10.1016/j.neuroimage.2017.06.070, PubMed 28666881
Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders
Neuroimage Clin, 15, 719-731
DOI 10.1016/j.nicl.2017.06.014, PubMed 28702349
Increased sensitivity to age-related differences in brain functional connectivity during continuous multiple object tracking compared to resting-state
Neuroimage, 148, 364-372
DOI 10.1016/j.neuroimage.2017.01.048, PubMed 28111190
Body language reading of emotion in schizophrenia: Associations with symptoms and functional outcome
Scand J Psychol, 58 (5), 359-366
DOI 10.1111/sjop.12381, PubMed 28833180
Metabolic risk factors in schizophrenia and bipolar disorder: The effect of comedication with selective serotonin reuptake inhibitors and antipsychotics
Eur Psychiatry, 48, 71-78
DOI 10.1016/j.eurpsy.2017.04.001, PubMed 29331603
Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis
Schizophr Res, 197, 253-260
DOI 10.1016/j.schres.2017.10.042, PubMed 29129510
4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients
Br J Clin Pharmacol, 83 (11), 2398-2405
DOI 10.1111/bcp.13341, PubMed 28585378
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
Brain Imaging Behav, 11 (5), 1497-1514
DOI 10.1007/s11682-016-9629-z, PubMed 27738994
Biclustered Independent Component Analysis for Complex Biomarker and Subtype Identification from Structural Magnetic Resonance Images in Schizophrenia
Front Psychiatry, 8, 179
DOI 10.3389/fpsyt.2017.00179, PubMed 29018368
Ion diffusion may introduce spurious current sources in current-source density (CSD) analysis
J Neurophysiol, 118 (1), 114-120
DOI 10.1152/jn.00976.2016, PubMed 28298307
Cortical thickness, cortical surface area and subcortical volumes in schizophrenia and bipolar disorder patients with cannabis use
Eur Neuropsychopharmacol, 28 (1), 37-47
DOI 10.1016/j.euroneuro.2017.11.019, PubMed 29254657
Predicting Outcome 12 Months after Mild Traumatic Brain Injury in Patients Admitted to a Neurosurgery Service
Front Neurol, 8, 125
DOI 10.3389/fneur.2017.00125, PubMed 28443058
White matter microstructure is associated with functional, cognitive and emotional symptoms 12 months after mild traumatic brain injury
Sci Rep, 7 (1), 13795
DOI 10.1038/s41598-017-13628-1, PubMed 29061970
Longitudinal changes in brain morphology from 4 weeks to 12 months after mild traumatic brain injury: Associations with cognitive functions and clinical variables
Brain Inj, 31 (5), 674-685
DOI 10.1080/02699052.2017.1283537, PubMed 28414250
Novel genetic loci associated with hippocampal volume
Nat Commun, 8, 13624
DOI 10.1038/ncomms13624, PubMed 28098162
Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group
Mol Psychiatry, 23 (4), 932-942
DOI 10.1038/mp.2017.73, PubMed 28461699
A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue
Schizophr Bull, 43 (4), 881-890
DOI 10.1093/schbul/sbw183, PubMed 28049760
The relation between face-emotion recognition and social function in adolescents with autism spectrum disorders: A case control study
PLoS One, 12 (10), e0186124
DOI 10.1371/journal.pone.0186124, PubMed 29020059
Event-Related Potentials in a Cued Go-NoGo Task Associated with Executive Functions in Adolescents with Autism Spectrum Disorder; A Case-Control Study
Front Neurosci, 11, 393
DOI 10.3389/fnins.2017.00393, PubMed 28744191
Side effect burden of antipsychotic drugs in real life - Impact of gender and polypharmacy
Prog Neuropsychopharmacol Biol Psychiatry, 82, 263-271
DOI 10.1016/j.pnpbp.2017.11.004, PubMed 29122637
Parents' Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder-Data from a Norwegian Sample
Int J Mol Sci, 18 (5)
DOI 10.3390/ijms18051078, PubMed 28524073
Delayed stabilization and individualization in connectome development are related to psychiatric disorders
Nat Neurosci, 20 (4), 513-515
DOI 10.1038/nn.4511, PubMed 28218917
Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group
Mol Psychiatry, 23 (5), 1261-1269
DOI 10.1038/mp.2017.170, PubMed 29038599
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets
Cell Rep, 21 (9), 2597-2613
DOI 10.1016/j.celrep.2017.11.028, PubMed 29186694
Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment
Schizophr Bull, 43 (3), 654-664
DOI 10.1093/schbul/sbw085, PubMed 27338279
Modeling prior information of common genetic variants improves gene discovery for neuroticism
Hum Mol Genet, 26 (22), 4530-4539
DOI 10.1093/hmg/ddx340, PubMed 28973307
Genetic risk scores and family history as predictors of schizophrenia in Nordic registers
Psychol Med, 48 (7), 1201-1208
DOI 10.1017/S0033291717002665, PubMed 28942743
Combinations of genetic variants associated with bipolar disorder
PLoS One, 12 (12), e0189739
DOI 10.1371/journal.pone.0189739, PubMed 29267373
Cerebellar volume and cerebellocerebral structural covariance in schizophrenia: a multisite mega-analysis of 983 patients and 1349 healthy controls
Mol Psychiatry, 23 (6), 1512-1520
DOI 10.1038/mp.2017.106, PubMed 28507318
A stepwise neuron model fitting procedure designed for recordings with high spatial resolution: Application to layer 5 pyramidal cells
J Neurosci Methods, 293, 264-283
DOI 10.1016/j.jneumeth.2017.10.007, PubMed 28993204
Pleiotropic effects of schizophrenia-associated genetic variants in neuron firing and cardiac pacemaking revealed by computational modeling
Transl Psychiatry, 7 (11), 5
DOI 10.1038/s41398-017-0007-4, PubMed 30446648
Persistent increase in TNF and IL-1 markers in severe mental disorders suggests trait-related inflammation: a one year follow-up study
Acta Psychiatr Scand, 136 (4), 400-408
DOI 10.1111/acps.12783, PubMed 28815548
Vitamin D Deficiency Associated With Cognitive Functioning in Psychotic Disorders
J Clin Psychiatry, 78 (7), e750-e757
DOI 10.4088/JCP.16m10880, PubMed 28493652
The quality of severe mental disorder diagnoses in a national health registry as compared to research diagnoses based on structured interview
BMC Psychiatry, 17 (1), 93
DOI 10.1186/s12888-017-1256-8, PubMed 28292279
Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations
NPJ Genom Med, 2, 24
DOI 10.1038/s41525-017-0027-2, PubMed 29263835
Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data
Transl Psychiatry, 7 (12), 1289
DOI 10.1038/s41398-017-0033-2, PubMed 29249828
Oxytocin system dysfunction as a common mechanism underlying metabolic syndrome and psychiatric symptoms in schizophrenia and bipolar disorders
Front Neuroendocrinol, 45, 1-10
DOI 10.1016/j.yfrne.2016.12.004, PubMed 28049009
Diurnal Variation and Twenty-Four Hour Sleep Deprivation Do Not Alter Supine Heart Rate Variability in Healthy Male Young Adults
PLoS One, 12 (2), e0170921
DOI 10.1371/journal.pone.0170921, PubMed 28151944
Dose-dependent social-cognitive effects of intranasal oxytocin delivered with novel Breath Powered device in adults with autism spectrum disorder: a randomized placebo-controlled double-blind crossover trial
Transl Psychiatry, 7 (5), e1136
DOI 10.1038/tp.2017.103, PubMed 28534875
[Medication-free hospital records - a measure not based on knowledge]
Tidsskr Nor Laegeforen, 137 (6), 426-427
DOI 10.4045/tidsskr.17.0091, PubMed 28332789
[Not Available]
Tidsskr Nor Laegeforen, 137 (9), 594-595
DOI 10.4045/tidsskr.17.0288, PubMed 28468447
Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment
J Am Acad Child Adolesc Psychiatry, 57 (2), 86-95
DOI 10.1016/j.jaac.2017.11.013, PubMed 29413154
Consistent Functional Connectivity Alterations in Schizophrenia Spectrum Disorder: A Multisite Study
Schizophr Bull, 43 (4), 914-924
DOI 10.1093/schbul/sbw145, PubMed 27872268
Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function
JAMA Psychiatry, 74 (10), 1065-1075
DOI 10.1001/jamapsychiatry.2017.1986, PubMed 28746715
Identification of genetic loci shared between schizophrenia and the Big Five personality traits
Sci Rep, 7 (1), 2222
DOI 10.1038/s41598-017-02346-3, PubMed 28533504
Correlation Between Serum Concentrations of N-Desmethylclozapine and Granulocyte Levels in Patients with Schizophrenia: A Retrospective Observational Study
CNS Drugs, 31 (11), 991-997
DOI 10.1007/s40263-017-0469-1, PubMed 28948574
Probing the Association between Early Evolutionary Markers and Schizophrenia
PLoS One, 12 (1), e0169227
DOI 10.1371/journal.pone.0169227, PubMed 28081145
Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis
Nat Genet, 49 (5), 801-805
DOI 10.1038/ng.3816, PubMed 28319091
Corrigendum: Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis
Nat Genet, 49 (8), 1286
DOI 10.1038/ng0817-1286b, PubMed 28747754
Psychiatric Genomics: An Update and an Agenda
Am J Psychiatry, 175 (1), 15-27
DOI 10.1176/appi.ajp.2017.17030283, PubMed 28969442
Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition
Acta Neuropathol, 135 (1), 85-93
DOI 10.1007/s00401-017-1789-4, PubMed 29177679
Polygenic hazard scores in preclinical Alzheimer disease
Ann Neurol, 82 (3), 484-488
DOI 10.1002/ana.25029, PubMed 28940650
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
Mol Psychiatry, 22 (3), 336-345
DOI 10.1038/mp.2016.244, PubMed 28093568
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
Mol Psychiatry, 22 (11), 1651-1652
DOI 10.1038/mp.2017.197, PubMed 29068436
The correlation between central and peripheral oxytocin concentrations: A systematic review and meta-analysis
Neurosci Biobehav Rev, 78, 117-124
DOI 10.1016/j.neubiorev.2017.04.017, PubMed 28442403
Impairment in emotion perception from body movements in individuals with bipolar I and bipolar II disorder is associated with functional capacity
Int J Bipolar Disord, 5 (1), 13
DOI 10.1186/s40345-017-0083-7, PubMed 28332121
Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium
Acta Psychiatr Scand, 135 (5), 439-447
DOI 10.1111/acps.12718, PubMed 28369804
Prefrontal cortical thinning links to negative symptoms in schizophrenia via the ENIGMA consortium
Psychol Med, 48 (1), 82-94
DOI 10.1017/S0033291717001283, PubMed 28545597
Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants
PLoS One, 12 (9), e0185663
DOI 10.1371/journal.pone.0185663, PubMed 28957430
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases
JAMA Neurol, 74 (7), 780-792
DOI 10.1001/jamaneurol.2017.0469, PubMed 28586827
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
Transl Psychiatry, 7 (6), e1155
DOI 10.1038/tp.2017.115, PubMed 28632202
Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia
Acta Neuropathol, 133 (5), 825-837
DOI 10.1007/s00401-017-1693-y, PubMed 28271184
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer
BMC Genomics, 18 (1), 270
DOI 10.1186/s12864-017-3620-y, PubMed 28359301
Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses
Brain Behav Immun, 65, 342-349
DOI 10.1016/j.bbi.2017.06.005, PubMed 28619247
Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not
Psychol Med, 48 (1), 43-49
DOI 10.1017/S0033291717001209, PubMed 28967348
Publications 2016
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Nat Neurosci, 19 (12), 1569-1582
DOI 10.1038/nn.4398, PubMed 27694991
A genetic association study of CSMD1 and CSMD2 with cognitive function
Brain Behav Immun, 61, 209-216
DOI 10.1016/j.bbi.2016.11.026, PubMed 27890662
Modelling difficulties in abstract thinking in psychosis: the importance of socio-developmental background
Cogn Neuropsychiatry, 22 (1), 39-52
DOI 10.1080/13546805.2016.1259998, PubMed 28005457
Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease
Ann Clin Transl Neurol, 3 (9), 668-77
DOI 10.1002/acn3.333, PubMed 27648456
Recovery from major depressive disorder episode after non-pharmacological treatment is associated with normalized cytokine levels
Acta Psychiatr Scand, 134 (1), 40-7
DOI 10.1111/acps.12576, PubMed 27028967
History of psychosis and previous episodes as potential explanatory factors for neurocognitive impairment in first-treatment bipolar I disorder
Bipolar Disord, 18 (2), 136-47
DOI 10.1111/bdi.12377, PubMed 26990158
Course of neurocognitive function in first treatment bipolar I disorder: One-year follow-up study
Psychiatry Res, 249, 286-292
DOI 10.1016/j.psychres.2016.12.048, PubMed 28142102
Somatic Comorbidity in Schizophrenia: Some Possible Biological Mechanisms Across the Life Span
Schizophr Bull, 42 (6), 1316-1319
DOI 10.1093/schbul/sbw028, PubMed 27033328
Age-related differences in brain network activation and co-activation during multiple object tracking
Brain Behav, 6 (11), e00533
DOI 10.1002/brb3.533, PubMed 27843692
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
Nat Genet, 48 (5), 510-8
DOI 10.1038/ng.3528, PubMed 26974007
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases
J Neurol Neurosurg Psychiatry, 88 (2), 152-164
DOI 10.1136/jnnp-2016-314411, PubMed 27899424
Metabolic Abnormalities Related to Treatment With Selective Serotonin Reuptake Inhibitors in Patients With Schizophrenia or Bipolar Disorder
J Clin Psychopharmacol, 36 (6), 615-620
DOI 10.1097/JCP.0000000000000582, PubMed 27749681
Relationship of suicide rates with climate and economic variables in Europe during 2000-2012
Ann Gen Psychiatry, 15, 19
DOI 10.1186/s12991-016-0106-2, PubMed 27508001
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept
Nat Neurosci, 19 (3), 420-431
DOI 10.1038/nn.4228, PubMed 26854805
Random Projection for Fast and Efficient Multivariate Correlation Analysis of High-Dimensional Data: A New Approach
Front Genet, 7, 102
DOI 10.3389/fgene.2016.00102, PubMed 27375677
A sequence variant associating with educational attainment also affects childhood cognition
Sci Rep, 6, 36189
DOI 10.1038/srep36189, PubMed 27811963
Effect of Ionic Diffusion on Extracellular Potentials in Neural Tissue
PLoS Comput Biol, 12 (11), e1005193
DOI 10.1371/journal.pcbi.1005193, PubMed 27820827
Contribution of oxytocin receptor polymorphisms to amygdala activation in schizophrenia spectrum disorders
BJPsych Open, 2 (6), 353-358
DOI 10.1192/bjpo.bp.116.003376, PubMed 27847593
The Association between Anomalous Self-experiences, Self-esteem and Depressive Symptoms in First Episode Schizophrenia
Front Hum Neurosci, 10, 557
DOI 10.3389/fnhum.2016.00557, PubMed 27872587
Volumetric and morphometric MRI findings in patients with mild traumatic brain injury
Brain Inj, 30 (13-14), 1683-1691
DOI 10.1080/02699052.2016.1199905, PubMed 27996331
Subcortical volumetric abnormalities in bipolar disorder
Mol Psychiatry, 21 (12), 1710-1716
DOI 10.1038/mp.2015.227, PubMed 26857596
Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics
Front Genet, 7, 15
DOI 10.3389/fgene.2016.00015, PubMed 26909100
Reduced load-dependent default mode network deactivation across executive tasks in schizophrenia spectrum disorders
Neuroimage Clin, 12, 389-96
DOI 10.1016/j.nicl.2016.08.012, PubMed 27622135
Parents' attitudes toward genetic research in autism spectrum disorder
Psychiatr Genet, 26 (2), 74-80
DOI 10.1097/YPG.0000000000000121, PubMed 26867185
Increased MRI-based cortical grey/white-matter contrast in sensory and motor regions in schizophrenia and bipolar disorder
Psychol Med, 46 (9), 1971-85
DOI 10.1017/S0033291716000593, PubMed 27049014
Brain volume change in first-episode psychosis: an effect of antipsychotic medication independent of BMI change
Acta Psychiatr Scand, 135 (2), 117-126
DOI 10.1111/acps.12677, PubMed 27925164
Task modulations and clinical manifestations in the brain functional connectome in 1615 fMRI datasets
Neuroimage, 147, 243-252
DOI 10.1016/j.neuroimage.2016.11.073, PubMed 27916665
Duration of untreated illness in first-treatment bipolar I disorder in relation to clinical outcome and cannabis use
Psychiatry Res, 246, 762-768
DOI 10.1016/j.psychres.2016.07.064, PubMed 27814886
Alcohol use disorders are associated with increased affective lability in bipolar disorder
J Affect Disord, 208, 316-324
DOI 10.1016/j.jad.2016.09.062, PubMed 27810713
Alcohol use is associated with thinner cerebral cortex and larger ventricles in schizophrenia, bipolar disorder and healthy controls
Psychol Med, 47 (4), 655-668
DOI 10.1017/S0033291716002920, PubMed 27830632
Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders
Nat Genet, 49 (1), 152-156
DOI 10.1038/ng.3736, PubMed 27918536
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Nat Genet, 49 (1), 27-35
DOI 10.1038/ng.3725, PubMed 27869829
Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women
JAMA Psychiatry, 73 (5), 497-505
DOI 10.1001/jamapsychiatry.2016.0129, PubMed 27007234
Functional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study
Biol Psychiatry Cogn Neurosci Neuroimaging, 1 (1), 49-59
DOI 10.1016/j.bpsc.2015.09.002, PubMed 26949748
Auditory Cortex Characteristics in Schizophrenia: Associations With Auditory Hallucinations
Schizophr Bull, 43 (1), 75-83
DOI 10.1093/schbul/sbw130, PubMed 27605526
Inflammatory evidence for the psychosis continuum model
Psychoneuroendocrinology, 67, 189-97
DOI 10.1016/j.psyneuen.2016.02.011, PubMed 26923849
Low vitamin D is associated with negative and depressive symptoms in psychotic disorders
Schizophr Res, 178 (1-3), 44-49
DOI 10.1016/j.schres.2016.08.024, PubMed 27595553
The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample
BMC Psychiatry, 16, 129
DOI 10.1186/s12888-016-0732-x, PubMed 27150464
Increased plasma levels of competing amino acids, rather than lowered plasma tryptophan levels, are associated with a non-response to treatment in major depression
Eur Neuropsychopharmacol, 26 (8), 1286-96
DOI 10.1016/j.euroneuro.2016.05.005, PubMed 27237997
Conservation of Distinct Genetically-Mediated Human Cortical Pattern
PLoS Genet, 12 (7), e1006143
DOI 10.1371/journal.pgen.1006143, PubMed 27459196
Resting-state high-frequency heart rate variability is related to respiratory frequency in individuals with severe mental illness but not healthy controls
Sci Rep, 6, 37212
DOI 10.1038/srep37212, PubMed 27853244
The impact of oxytocin administration on brain activity: a systematic review and meta-analysis protocol
Syst Rev, 5 (1), 205
DOI 10.1186/s13643-016-0386-2, PubMed 27899138
Low dose intranasal oxytocin delivered with Breath Powered device dampens amygdala response to emotional stimuli: A peripheral effect-controlled within-subjects randomized dose-response fMRI trial
Psychoneuroendocrinology, 69, 180-8
DOI 10.1016/j.psyneuen.2016.04.010, PubMed 27107209
Reliability of basal plasma vasopressin concentrations in healthy male adults
Acta Neuropsychiatr, 29 (5), 315-321
DOI 10.1017/neu.2016.67, PubMed 27923411
Premorbid cannabis use is associated with more symptoms and poorer functioning in schizophrenia spectrum disorder
Psychol Med, 46 (15), 3127-3136
DOI 10.1017/S0033291716001999, PubMed 27534999
25th Annual Computational Neuroscience Meeting: CNS-2016
BMC Neurosci, 17 Suppl 1 (Suppl 1), 54
DOI 10.1186/s12868-016-0283-6, PubMed 27534393
Global brain connectivity alterations in patients with schizophrenia and bipolar spectrum disorders
J Psychiatry Neurosci, 41 (5), 331-41
DOI 10.1503/jpn.150159, PubMed 26854755
Lipid profiles in schizophrenia associated with clinical traits: a five year follow-up study
BMC Psychiatry, 16 (1), 299
DOI 10.1186/s12888-016-1006-3, PubMed 27562545
Serum levels of second-generation antipsychotics are associated with cognitive function in psychotic disorders
World J Biol Psychiatry, 18 (6), 471-482
DOI 10.1080/15622975.2016.1245441, PubMed 27712130
Serum concentrations of mood stabilizers are associated with memory, but not other cognitive domains in psychosis spectrum disorders; explorative analyses in a naturalistic setting
Int J Bipolar Disord, 4 (1), 24
DOI 10.1186/s40345-016-0067-z, PubMed 27858347
Genetic evidence for a role of the SREBP transcription system and lipid biosynthesis in schizophrenia and antipsychotic treatment
Eur Neuropsychopharmacol, 27 (6), 589-598
DOI 10.1016/j.euroneuro.2016.07.011, PubMed 27492885
VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls
Br J Psychiatry, 209 (2), 114-20
DOI 10.1192/bjp.bp.115.161950, PubMed 26941264
The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements
Philos Trans R Soc Lond B Biol Sci, 371 (1705)
DOI 10.1098/rstb.2015.0356, PubMed 27574309
Cell type specificity of neurovascular coupling in cerebral cortex
Elife, 5
DOI 10.7554/eLife.14315, PubMed 27244241
The relationship between central and peripheral oxytocin concentrations: a systematic review and meta-analysis protocol
Syst Rev, 5, 49
DOI 10.1186/s13643-016-0225-5, PubMed 27037015
Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis
Biol Psychiatry, 82 (9), 634-641
DOI 10.1016/j.biopsych.2016.08.040, PubMed 27890468
Association of Butyrylcholinesterase-K Allele and Apolipoprotein E ɛ4 Allele with Cognitive Decline in Dementia with Lewy Bodies and Alzheimer's Disease
J Alzheimers Dis, 50 (2), 567-76
DOI 10.3233/JAD-150750, PubMed 26757188
Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors
Mult Scler, 22 (14), 1783-1793
DOI 10.1177/1352458516635873, PubMed 26920376
Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS
PLoS Genet, 12 (1), e1005803
DOI 10.1371/journal.pgen.1005803, PubMed 26808560
Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease
JAMA Neurol, 73 (6), 691-7
DOI 10.1001/jamaneurol.2016.0150, PubMed 27088644
Pleiotropic Analysis of Lung Cancer and Blood Triglycerides
J Natl Cancer Inst, 108 (12)
DOI 10.1093/jnci/djw167, PubMed 27565901
A history of childhood trauma is associated with slower improvement rates: Findings from a one-year follow-up study of patients with a first-episode psychosis
BMC Psychiatry, 16, 126
DOI 10.1186/s12888-016-0827-4, PubMed 27146044
The role of childhood trauma in bipolar disorders
Int J Bipolar Disord, 4 (1), 2
DOI 10.1186/s40345-015-0042-0, PubMed 26763504
Affective lability mediates the association between childhood trauma and suicide attempts, mixed episodes and co-morbid anxiety disorders in bipolar disorders
Psychol Med, 47 (5), 902-912
DOI 10.1017/S0033291716003081, PubMed 27894372
Childhood trauma is associated with increased brain responses to emotionally negative as compared with positive faces in patients with psychotic disorders
Psychol Med, 47 (4), 669-679
DOI 10.1017/S0033291716002762, PubMed 27834153
Publications 2015
Attentional load modulates large-scale functional brain connectivity beyond the core attention networks
Neuroimage, 109, 260-72
DOI 10.1016/j.neuroimage.2015.01.026, PubMed 25595500
Functional connectivity indicates differential roles for the intraparietal sulcus and the superior parietal lobule in multiple object tracking
Neuroimage, 123, 129-37
DOI 10.1016/j.neuroimage.2015.08.029, PubMed 26299796
Polygenic risk scores in bipolar disorder subgroups
J Affect Disord, 183, 310-4
DOI 10.1016/j.jad.2015.05.021, PubMed 26047958
Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
PLoS One, 10 (4), e0123057
DOI 10.1371/journal.pone.0123057, PubMed 25853426
Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms
PLoS One, 10 (5), e0128048
DOI 10.1371/journal.pone.0128048, PubMed 25978331
Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
PLoS Genet, 11 (11), e1005544
DOI 10.1371/journal.pgen.1005544, PubMed 26540268
Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs
J Psychopharmacol, 29 (8), 884-91
DOI 10.1177/0269881115584469, PubMed 25944848
The development of insight and its relationship with suicidality over one year follow-up in patients with first episode psychosis
Schizophr Res, 162 (1-3), 97-102
DOI 10.1016/j.schres.2015.01.004, PubMed 25620119
Influence of light exposure during early life on the age of onset of bipolar disorder
J Psychiatr Res, 64, 1-8
DOI 10.1016/j.jpsychires.2015.03.013, PubMed 25862378
Psychosis: clinical insight and beliefs in immigrants in their first episode
Early Interv Psychiatry, 12 (2), 185-192
DOI 10.1111/eip.12297, PubMed 26663787
Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness
Am J Med Genet B Neuropsychiatr Genet, 171B (2), 276-89
DOI 10.1002/ajmg.b.32402, PubMed 26663532
Effects of haloperidol and aripiprazole on the human mesolimbic motivational system: A pharmacological fMRI study
Eur Neuropsychopharmacol, 25 (12), 2252-61
DOI 10.1016/j.euroneuro.2015.09.016, PubMed 26476705
No difference in frontal cortical activity during an executive functioning task after acute doses of aripiprazole and haloperidol
Front Hum Neurosci, 9, 296
DOI 10.3389/fnhum.2015.00296, PubMed 26074803
Assessing brain structural associations with working-memory related brain patterns in schizophrenia and healthy controls using linked independent component analysis
Neuroimage Clin, 9, 253-63
DOI 10.1016/j.nicl.2015.08.010, PubMed 26509112
Cognitive Effort and Schizophrenia Modulate Large-Scale Functional Brain Connectivity
Schizophr Bull, 41 (6), 1360-9
DOI 10.1093/schbul/sbv013, PubMed 25731885
Large-scale genomics unveil polygenic architecture of human cortical surface area
Nat Commun, 6, 7549
DOI 10.1038/ncomms8549, PubMed 26189703
Ongoing episode of major depressive disorder is not associated with elevated plasma levels of kynurenine pathway markers
Psychoneuroendocrinology, 56, 12-22
DOI 10.1016/j.psyneuen.2015.02.011, PubMed 25770856
Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease
Circulation, 131 (23), 2061-2069
DOI 10.1161/CIRCULATIONAHA.115.015489, PubMed 25862742
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus
Mol Psychiatry, 20 (12), 1588-95
DOI 10.1038/mp.2015.6, PubMed 25687773
Theory of mind in schizophrenia: error types and associations with symptoms
Schizophr Res, 162 (1-3), 42-6
DOI 10.1016/j.schres.2015.01.024, PubMed 25623602
MicroRNAs enrichment in GWAS of complex human phenotypes
BMC Genomics, 16 (1), 304
DOI 10.1186/s12864-015-1513-5, PubMed 25884492
Association between Genetic Variation in the Oxytocin Receptor Gene and Emotional Withdrawal, but not between Oxytocin Pathway Genes and Diagnosis in Psychotic Disorders
Front Hum Neurosci, 9, 9
DOI 10.3389/fnhum.2015.00009, PubMed 25667571
Lithium treatment and hippocampal subfields and amygdala volumes in bipolar disorder
Bipolar Disord, 17 (5), 496-506
DOI 10.1111/bdi.12295, PubMed 25809287
High levels of anomalous self-experience are associated with longer duration of untreated psychosis
Early Interv Psychiatry, 11 (2), 133-138
DOI 10.1111/eip.12220, PubMed 25589153
No progressive brain changes during a 1-year follow-up of patients with first-episode psychosis
Psychol Med, 46 (3), 589-98
DOI 10.1017/S003329171500210X, PubMed 26526001
Cannabis use is associated with 3years earlier onset of schizophrenia spectrum disorder in a naturalistic, multi-site sample (N=1119)
Schizophr Res, 170 (1), 217-21
DOI 10.1016/j.schres.2015.11.027, PubMed 26682958
Common genetic variants influence human subcortical brain structures
Nature, 520 (7546), 224-9
DOI 10.1038/nature14101, PubMed 25607358
Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders
Nord J Psychiatry, 70 (4), 276-9
DOI 10.3109/08039488.2015.1095944, PubMed 26559242
Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls
Schizophr Res, 165 (2-3), 188-94
DOI 10.1016/j.schres.2015.04.004, PubMed 25956633
Association between cytokine levels, verbal memory and hippocampus volume in psychotic disorders and healthy controls
Acta Psychiatr Scand, 133 (1), 53-62
DOI 10.1111/acps.12467, PubMed 26189721
Genome-wide autozygosity is associated with lower general cognitive ability
Mol Psychiatry, 21 (6), 837-43
DOI 10.1038/mp.2015.120, PubMed 26390830
A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia
Biol Psychiatry, 80 (4), 323-330
DOI 10.1016/j.biopsych.2015.09.021, PubMed 26682468
Stability of executive functions in first episode psychosis: One year follow up study
Psychiatry Res, 228 (3), 475-81
DOI 10.1016/j.psychres.2015.05.060, PubMed 26165960
Microarray Analysis of Copy Number Variants on the Human Y Chromosome Reveals Novel and Frequent Duplications Overrepresented in Specific Haplogroups
PLoS One, 10 (8), e0137223
DOI 10.1371/journal.pone.0137223, PubMed 26322892
Cigarette smoking is associated with thinner cingulate and insular cortices in patients with severe mental illness
J Psychiatry Neurosci, 40 (4), 241-9
DOI 10.1503/jpn.140163, PubMed 25672482
The brain functional connectome is robustly altered by lack of sleep
Neuroimage, 127, 324-332
DOI 10.1016/j.neuroimage.2015.12.028, PubMed 26712339
Disintegration of Sensorimotor Brain Networks in Schizophrenia
Schizophr Bull, 41 (6), 1326-35
DOI 10.1093/schbul/sbv060, PubMed 25943122
Continued cannabis use at one year follow up is associated with elevated mood and lower global functioning in bipolar I disorder
BMC Psychiatry, 15, 11
DOI 10.1186/s12888-015-0389-x, PubMed 25651990
Cannabis use disorder is associated with greater illness severity in tobacco smoking patients with bipolar disorder
J Affect Disord, 190, 286-293
DOI 10.1016/j.jad.2015.10.023, PubMed 26544611
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors
Circ Res, 118 (1), 83-94
DOI 10.1161/CIRCRESAHA.115.306629, PubMed 26487741
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis
Int J Epidemiol, 44 (5), 1706-21
DOI 10.1093/ije/dyv136, PubMed 26286434
Combinations of Genetic Data Present in Bipolar Patients, but Absent in Control Persons
PLoS One, 10 (11), e0143432
DOI 10.1371/journal.pone.0143432, PubMed 26587987
Brain structure abnormalities in first-episode psychosis patients with persistent apathy
Schizophr Res, 164 (1-3), 59-64
DOI 10.1016/j.schres.2015.03.001, PubMed 25818626
Vitamin D status in psychotic disorder patients and healthy controls--The influence of ethnic background
Psychiatry Res, 230 (2), 616-21
DOI 10.1016/j.psychres.2015.10.015, PubMed 26500071
Effects of ECT in treatment of depression: study protocol for a prospective neuroradiological study of acute and longitudinal effects on brain structure and function
BMC Psychiatry, 15, 94
DOI 10.1186/s12888-015-0477-y, PubMed 25927716
The promise and pitfalls of intranasally administering psychopharmacological agents for the treatment of psychiatric disorders
Mol Psychiatry, 21 (1), 29-38
DOI 10.1038/mp.2015.166, PubMed 26552590
Reduced heart rate variability in schizophrenia and bipolar disorder compared to healthy controls
Acta Psychiatr Scand, 133 (1), 44-52
DOI 10.1111/acps.12498, PubMed 26371411
Low-dose oxytocin delivered intranasally with Breath Powered device affects social-cognitive behavior: a randomized four-way crossover trial with nasal cavity dimension assessment
Transl Psychiatry, 5 (7), e602
DOI 10.1038/tp.2015.93, PubMed 26171983
Negative symptoms in schizophrenia show association with amygdala volumes and neural activation during affective processing
Acta Neuropsychiatr, 27 (4), 213-20
DOI 10.1017/neu.2015.11, PubMed 25777814
Negative symptoms in schizophrenia are associated with aberrant striato-cortical connectivity in a rewarded perceptual decision-making task
Neuroimage Clin, 8, 290-7
DOI 10.1016/j.nicl.2015.04.025, PubMed 26106553
Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci
PLoS One, 10 (12), e0144531
DOI 10.1371/journal.pone.0144531, PubMed 26695485
Population genetic differentiation of height and body mass index across Europe
Nat Genet, 47 (11), 1357-62
DOI 10.1038/ng.3401, PubMed 26366552
Response to Kotzalidis et al
Am J Psychiatry, 172 (3), 294-5
DOI 10.1176/appi.ajp.2014.14101366r, PubMed 25727541
Response to Kellner and Fink
Am J Psychiatry, 172 (3), 295-6
DOI 10.1176/appi.ajp.2014.14101284r, PubMed 25727543
New statistical approaches exploit the polygenic architecture of schizophrenia--implications for the underlying neurobiology
Curr Opin Neurobiol, 36, 89-98
DOI 10.1016/j.conb.2015.10.008, PubMed 26555806
Association between serum lipids and membrane fatty acids and clinical characteristics in patients with schizophrenia
Acta Psychiatr Scand, 132 (4), 293-300
DOI 10.1111/acps.12388, PubMed 25597473
Genetic Markers of Human Evolution Are Enriched in Schizophrenia
Biol Psychiatry, 80 (4), 284-292
DOI 10.1016/j.biopsych.2015.10.009, PubMed 26681495
Serum level of venlafaxine is associated with better memory in psychotic disorders
Schizophr Res, 169 (1-3), 386-392
DOI 10.1016/j.schres.2015.10.021, PubMed 26516101
Delayed sleep phase: An important circadian subtype of sleep disturbance in bipolar disorders
J Affect Disord, 191, 156-63
DOI 10.1016/j.jad.2015.11.025, PubMed 26655861
Sleep problems in bipolar disorders: more than just insomnia
Acta Psychiatr Scand, 133 (5), 368-77
DOI 10.1111/acps.12523, PubMed 26590799
Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease
Nat Genet, 47 (5), 445-7
DOI 10.1038/ng.3246, PubMed 25807283
Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder
PLoS One, 10 (7), e0134202
DOI 10.1371/journal.pone.0134202, PubMed 26222050
ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide
Neuroimage, 145 (Pt B), 389-408
DOI 10.1016/j.neuroimage.2015.11.057, PubMed 26658930
An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies
PLoS Genet, 11 (12), e1005717
DOI 10.1371/journal.pgen.1005717, PubMed 26714184
Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment
Am J Med Genet B Neuropsychiatr Genet, 168B (5), 363-73
DOI 10.1002/ajmg.b.32319, PubMed 25951819
Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium
Mol Psychiatry, 21 (4), 547-53
DOI 10.1038/mp.2015.63, PubMed 26033243
Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium
Mol Psychiatry, 21 (4), 585
DOI 10.1038/mp.2015.118, PubMed 26283641
Brain structure characteristics in intellectually superior schizophrenia
Psychiatry Res, 232 (1), 123-9
DOI 10.1016/j.pscychresns.2015.02.005, PubMed 25754688
To the editors: Reply to Anna R. Docherty
Psychiatry Res, 233 (3), 497
DOI 10.1016/j.pscychresns.2015.07.022, PubMed 26319295
A social path to functioning in schizophrenia: From social self-efficacy through negative symptoms to social functional capacity
Psychiatry Res, 228 (3), 803-7
DOI 10.1016/j.psychres.2015.05.019, PubMed 26089018
Genome-wide analysis of attention deficit hyperactivity disorder in Norway
PLoS One, 10 (4), e0122501
DOI 10.1371/journal.pone.0122501, PubMed 25875332
Unhelpful metacognitive beliefs in early psychosis are associated with affective symptoms and childhood social adjustment
Schizophr Res, 169 (1-3), 280-285
DOI 10.1016/j.schres.2015.10.026, PubMed 26519990
Publications 2014
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci
Mol Psychiatry, 20 (2), 207-14
DOI 10.1038/mp.2013.195, PubMed 24468824
Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes
Hypertension, 63 (4), 819-26
DOI 10.1161/HYPERTENSIONAHA.113.02077, PubMed 24396023
Shared common variants in prostate cancer and blood lipids
Int J Epidemiol, 43 (4), 1205-14
DOI 10.1093/ije/dyu090, PubMed 24786909
Relationship between sunlight and the age of onset of bipolar disorder: an international multisite study
J Affect Disord, 167, 104-11
DOI 10.1016/j.jad.2014.05.032, PubMed 24953482
Influence of birth cohort on age of onset cluster analysis in bipolar I disorder
Eur Psychiatry, 30 (1), 99-105
DOI 10.1016/j.eurpsy.2014.10.005, PubMed 25498240
The impact of immigration and visible minority status on psychosis symptom profile
Soc Psychiatry Psychiatr Epidemiol, 49 (11), 1747-57
DOI 10.1007/s00127-014-0897-x, PubMed 24927946
Childhood trauma mediates the association between ethnic minority status and more severe hallucinations in psychotic disorder
Psychol Med, 45 (1), 133-42
DOI 10.1017/S0033291714001135, PubMed 25065296
A genome-wide association study of anorexia nervosa
Mol Psychiatry, 19 (10), 1085-94
DOI 10.1038/mp.2013.187, PubMed 24514567
Working memory networks and activation patterns in schizophrenia and bipolar disorder: comparison with healthy controls
Br J Psychiatry, 204, 290-8
DOI 10.1192/bjp.bp.113.129254, PubMed 24434074
Environmental factors during adolescence associated with later development of psychotic disorders - a nested case-control study
Psychiatry Res, 215 (3), 579-85
DOI 10.1016/j.psychres.2013.12.048, PubMed 24495574
The plasma levels of various cytokines are increased during ongoing depression and are reduced to normal levels after recovery
Psychoneuroendocrinology, 45, 77-86
DOI 10.1016/j.psyneuen.2014.03.019, PubMed 24845179
The role of clusterin in amyloid-β-associated neurodegeneration
JAMA Neurol, 71 (2), 180-7
DOI 10.1001/jamaneurol.2013.4560, PubMed 24378367
Association between altered brain morphology and elevated peripheral endothelial markers--implications for psychotic disorders
Schizophr Res, 161 (2-3), 222-8
DOI 10.1016/j.schres.2014.11.006, PubMed 25433965
Risk factors of cycle acceleration in acutely admitted patients with bipolar disorder
Acta Psychiatr Scand, 130 (5), 388-96
DOI 10.1111/acps.12308, PubMed 24962060
Exploring the agreement between questionnaire information and DSM-IV diagnoses of comorbid psychopathology in children with autism spectrum disorders
Autism, 19 (4), 433-42
DOI 10.1177/1362361314526003, PubMed 24637430
Comparison of variants of canonical correlation analysis and partial least squares for combined analysis of MRI and genetic data
Neuroimage, 107, 289-310
DOI 10.1016/j.neuroimage.2014.12.025, PubMed 25527238
An attempt to identify single nucleotide polymorphisms contributing to possible relationships between personality traits and oxytocin-related genes
Neuropsychobiology, 69 (1), 25-30
DOI 10.1159/000356965, PubMed 24458227
Anomalous self-experience and childhood trauma in first-episode schizophrenia
Compr Psychiatry, 56, 35-41
DOI 10.1016/j.comppsych.2014.10.005, PubMed 25458477
In vivo hippocampal subfield volumes in schizophrenia and bipolar disorder
Biol Psychiatry, 77 (6), 581-8
DOI 10.1016/j.biopsych.2014.06.020, PubMed 25127742
Glutamate as a mediating transmitter for auditory hallucinations in schizophrenia: a (1)H MRS study
Schizophr Res, 161 (2-3), 252-60
DOI 10.1016/j.schres.2014.11.015, PubMed 25542859
Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls
Schizophr Bull, 41 (3), 736-43
DOI 10.1093/schbul/sbu152, PubMed 25392519
The effect of electroconvulsive therapy on neurocognitive function in treatment-resistant bipolar disorder depression
J Clin Psychiatry, 75 (11), e1306-13
DOI 10.4088/JCP.13m08960, PubMed 25470096
Cannabis use in first-treatment bipolar I disorder: relations to clinical characteristics
Early Interv Psychiatry, 10 (1), 36-44
DOI 10.1111/eip.12138, PubMed 24739233
Increased amygdala and visual cortex activity and functional connectivity towards stimulus novelty is associated with state anxiety
PLoS One, 9 (4), e96146
DOI 10.1371/journal.pone.0096146, PubMed 24755617
The human amygdala encodes value and space during decision making
Neuroimage, 101, 712-9
DOI 10.1016/j.neuroimage.2014.07.055, PubMed 25094017
The left inferior frontal gyrus is involved in adjusting response bias during a perceptual decision-making task
Brain Behav, 4 (3), 398-407
DOI 10.1002/brb3.223, PubMed 24944869
Increased mortality in schizophrenia due to cardiovascular disease - a non-systematic review of epidemiology, possible causes, and interventions
Front Psychiatry, 5, 137
DOI 10.3389/fpsyt.2014.00137, PubMed 25309466
Treatment-resistant bipolar depression: a randomized controlled trial of electroconvulsive therapy versus algorithm-based pharmacological treatment
Am J Psychiatry, 172 (1), 41-51
DOI 10.1176/appi.ajp.2014.13111517, PubMed 25219389
Cognitive Behavior Therapy in First-Episode Psychosis With a Focus on Depression, Anxiety, and Self-Esteem
Cogn. Behav. Pract., 21 (1), 43-54
Altered systemic cortisol metabolism in bipolar disorder and schizophrenia spectrum disorders
J Psychiatr Res, 52, 57-62
DOI 10.1016/j.jpsychires.2014.01.017, PubMed 24534618
Polygenic risk score and the psychosis continuum model
Acta Psychiatr Scand, 130 (4), 311-7
DOI 10.1111/acps.12307, PubMed 24961959
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Brain Imaging Behav, 8 (2), 153-82
DOI 10.1007/s11682-013-9269-5, PubMed 24399358
Neurocognitive Decrements are Present in Intellectually Superior Schizophrenia
Front Psychiatry, 5, 45
DOI 10.3389/fpsyt.2014.00045, PubMed 24847284
ANK3 gene expression in bipolar disorder and schizophrenia
Br J Psychiatry, 205 (3), 244-5
DOI 10.1192/bjp.bp.114.145433, PubMed 24809399
Covariate-modulated local false discovery rate for genome-wide association studies
Bioinformatics, 30 (15), 2098-104
DOI 10.1093/bioinformatics/btu145, PubMed 24711653
Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders
World J Biol Psychiatry, 16 (3), 171-9
DOI 10.3109/15622975.2014.953011, PubMed 25264289
Affective lability in patients with bipolar disorders is associated with high levels of childhood trauma
Psychiatry Res, 218 (1-2), 252-5
DOI 10.1016/j.psychres.2014.03.046, PubMed 24803185
Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders
J Psychiatr Res, 59, 14-21
DOI 10.1016/j.jpsychires.2014.08.011, PubMed 25246365
Psychometric properties of the Affective Lability Scale (54 and 18-item version) in patients with bipolar disorder, first-degree relatives, and healthy controls
J Affect Disord, 172, 375-80
DOI 10.1016/j.jad.2014.10.028, PubMed 25451440
Publications 2013
A comprehensive family-based replication study of schizophrenia genes
JAMA Psychiatry, 70 (6), 573-81
DOI 10.1001/jamapsychiatry.2013.288, PubMed 23894747
Neurocognitive features in subgroups of bipolar disorder
Bipolar Disord, 15 (3), 272-83
DOI 10.1111/bdi.12061, PubMed 23521608
Would Kraepelin reconsider the distinction between schizophrenia and bipolar disorder if he had access to recent molecular genetics evidence?
Acta Neuropsychiatr., 25 (6), 309-310
DOI 10.1017/neu.2013.62
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors
Am J Hum Genet, 92 (2), 197-209
DOI 10.1016/j.ajhg.2013.01.001, PubMed 23375658
Boosting the power of schizophrenia genetics by leveraging new statistical tools
Schizophr Bull, 40 (1), 13-7
DOI 10.1093/schbul/sbt168, PubMed 24319118
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate
PLoS Genet, 9 (4), e1003455
DOI 10.1371/journal.pgen.1003455, PubMed 23637625
ZNF804A and cortical thickness in schizophrenia and bipolar disorder
Psychiatry Res, 212 (2), 154-7
DOI 10.1016/j.pscychresns.2013.01.007, PubMed 23562677
Aversive event anticipation affects connectivity between the ventral striatum and the orbitofrontal cortex in an fMRI avoidance task
PLoS One, 8 (6), e68494
DOI 10.1371/journal.pone.0068494, PubMed 23826392
Neuropsychological testing of cognitive impairment in euthymic bipolar disorder: an individual patient data meta-analysis
Acta Psychiatr Scand, 128 (3), 149-62
DOI 10.1111/acps.12133, PubMed 23617548
Self-reported symptoms and health service use in adolescence in persons who later develop psychotic disorders: a prospective case-control study
Early Interv Psychiatry, 9 (3), 221-7
DOI 10.1111/eip.12102, PubMed 24224904
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Nat Genet, 45 (9), 984-94
DOI 10.1038/ng.2711, PubMed 23933821
Heart fatty acid binding protein and Aβ-associated Alzheimer's neurodegeneration
Mol Neurodegener, 8, 39
DOI 10.1186/1750-1326-8-39, PubMed 24088526
Evidence for reduced dentate gyrus and fimbria volume in bipolar II disorder
Bipolar Disord, 15 (2), 167-76
DOI 10.1111/bdi.12046, PubMed 23317454
Bipolar II disorder is associated with thinning of prefrontal and temporal cortices involved in affect regulation
Bipolar Disord, 15 (8), 855-64
DOI 10.1111/bdi.12117, PubMed 23980618
Childhood trauma is associated with severe clinical characteristics of bipolar disorders
J Clin Psychiatry, 74 (10), 991-8
DOI 10.4088/JCP.13m08353, PubMed 24229750
Apathy, poor verbal memory and male gender predict lower psychosocial functioning one year after the first treatment of psychosis
Psychiatry Res, 210 (1), 55-61
DOI 10.1016/j.psychres.2013.02.007, PubMed 23489592
A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder
PLoS One, 8 (12), e81052
DOI 10.1371/journal.pone.0081052, PubMed 24349030
Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia
J Affect Disord, 163, 110-4
DOI 10.1016/j.jad.2013.12.018, PubMed 24461634
Object relations, reality testing, and social withdrawal in schizophrenia and bipolar disorder
J Nerv Ment Dis, 201 (3), 222-5
DOI 10.1097/NMD.0b013e3182848ae0, PubMed 23407207
Anomalous self-experiences contribute independently to social dysfunction in the early phases of schizophrenia and psychotic bipolar disorder
Compr Psychiatry, 55 (3), 475-82
DOI 10.1016/j.comppsych.2013.11.010, PubMed 24378241
Pre- and perinatal hypoxia associated with hippocampus/amygdala volume in bipolar disorder
Psychol Med, 44 (5), 975-85
DOI 10.1017/S0033291713001529, PubMed 23803260
Normal birth weight variation is related to cortical morphology across the psychosis spectrum
Schizophr Bull, 40 (2), 410-9
DOI 10.1093/schbul/sbt005, PubMed 23419977
Social functioning in first contact mania: clinical and neurocognitive correlates
Compr Psychiatry, 54 (5), 432-8
DOI 10.1016/j.comppsych.2012.12.016, PubMed 23351832
European Network of Bipolar Research Expert Centre (ENBREC): a network to foster research and promote innovative care
Int J Bipolar Disord, 1, 2
DOI 10.1186/2194-7511-1-2, PubMed 25505669
Genetic clustering on the hippocampal surface for genome-wide association studies
Med Image Comput Comput Assist Interv, 16 (Pt 2), 690-7
DOI 10.1007/978-3-642-40763-5_85, PubMed 24579201
Genetic Clustering on the Hippocampal Surface for Genome-Wide Association Studies
LECT NOTES COMPUT SC, 8150, 690-697
Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia and bipolar disorder
Schizophr Res, 145 (1-3), 36-42
DOI 10.1016/j.schres.2012.12.023, PubMed 23403415
Neurocognitive profiles in treatment-resistant bipolar I and bipolar II disorder depression
BMC Psychiatry, 13, 105
DOI 10.1186/1471-244X-13-105, PubMed 23557429
Indications of a dose-response relationship between cannabis use and age at onset in bipolar disorder
Psychiatry Res, 215 (1), 101-4
DOI 10.1016/j.psychres.2013.10.029, PubMed 24262665
One year follow-up of alcohol and illicit substance use in first-episode psychosis: does gender matter?
Compr Psychiatry, 55 (2), 274-82
DOI 10.1016/j.comppsych.2013.08.018, PubMed 24262129
Patterns of childhood adverse events are associated with clinical characteristics of bipolar disorder
BMC Psychiatry, 13, 97
DOI 10.1186/1471-244X-13-97, PubMed 23522391
Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)
Mol Psychiatry, 19 (2), 168-74
DOI 10.1038/mp.2013.166, PubMed 24342994
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
Nat Genet, 45 (6), 670-5
DOI 10.1038/ng.2616, PubMed 23603763
Clinical characteristics in schizophrenia patients with or without suicide attempts and non-suicidal self-harm--a cross-sectional study
BMC Psychiatry, 13, 255
DOI 10.1186/1471-244X-13-255, PubMed 24106884
Migrant background and ethnic minority status as predictors for duration of untreated psychosis
Early Interv Psychiatry, 9 (1), 61-5
DOI 10.1111/eip.12106, PubMed 24225002
Reduced brain cortical folding in schizophrenia revealed in two independent samples
Schizophr Res, 152 (2-3), 333-8
DOI 10.1016/j.schres.2013.11.032, PubMed 24365403
Motivation alters response bias and neural activation patterns in a perceptual decision-making task
Neuroscience, 238, 135-47
DOI 10.1016/j.neuroscience.2013.02.015, PubMed 23428623
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia
Mol Psychiatry, 19 (9), 1017-1024
DOI 10.1038/mp.2013.138, PubMed 24280982
Occupational outcome in bipolar disorder is not predicted by premorbid functioning and intelligence
Bipolar Disord, 15 (3), 294-305
DOI 10.1111/bdi.12056, PubMed 23527993
All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs
PLoS Genet, 9 (4), e1003449
DOI 10.1371/journal.pgen.1003449, PubMed 23637621
No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes
J Affect Disord, 151 (1), 291-7
DOI 10.1016/j.jad.2013.06.008, PubMed 23820096
CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls
PLoS One, 8 (2), e56970
DOI 10.1371/journal.pone.0056970, PubMed 23437284
Frontotemporal hypoactivity during a reality monitoring paradigm is associated with delusions in patients with schizophrenia spectrum disorders
Cogn Neuropsychiatry, 19 (2), 97-115
DOI 10.1080/13546805.2013.776495, PubMed 23756081
Social cognition and clinical insight in schizophrenia and bipolar disorder
J Nerv Ment Dis, 201 (6), 445-51
DOI 10.1097/NMD.0b013e31829480c8, PubMed 23686158
The neural correlates of cognitive control in bipolar I disorder: an fMRI study of medial frontal cortex activation during a Go/No-go task
Neurosci Lett, 549, 51-6
DOI 10.1016/j.neulet.2013.06.010, PubMed 23778236
Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders
Psychol Med, 44 (8), 1653-62
DOI 10.1017/S0033291713002316, PubMed 24028906
BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses
Prog Neuropsychopharmacol Biol Psychiatry, 46, 181-8
DOI 10.1016/j.pnpbp.2013.07.008, PubMed 23876786
Publications 2012
An association between affective lability and executive functioning in bipolar disorder
Psychiatry Res, 198 (1), 58-61
DOI 10.1016/j.psychres.2011.12.044, PubMed 22405635
D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians
Eur Arch Psychiatry Clin Neurosci, 262 (7), 549-56
DOI 10.1007/s00406-012-0313-z, PubMed 22454242
Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study
Psychiatry Res, 197 (3), 327-36
DOI 10.1016/j.psychres.2011.12.036, PubMed 22417934
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans
Proc Natl Acad Sci U S A, 109 (10), 3985-90
DOI 10.1073/pnas.1105829109, PubMed 22343285
Impact of sunlight on the age of onset of bipolar disorder
Bipolar Disord, 14 (6), 654-63
DOI 10.1111/j.1399-5618.2012.01025.x, PubMed 22612720
Social dysfunction in first-episode psychosis and relations to neurocognition, duration of untreated psychosis and clinical symptoms
Psychiatry Res, 207 (1-2), 33-9
DOI 10.1016/j.psychres.2012.10.010, PubMed 23153893
Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach
Transl Psychiatry, 2 (7), e143
DOI 10.1038/tp.2012.67, PubMed 22828495
Linkage-disequilibrium-based binning affects the interpretation of GWASs
Am J Hum Genet, 90 (4), 727-33
DOI 10.1016/j.ajhg.2012.02.025, PubMed 22444669
Apolipoprotein E epsilon4 does not modulate amyloid-β-associated neurodegeneration in preclinical Alzheimer disease
AJNR Am J Neuroradiol, 34 (3), 505-10
DOI 10.3174/ajnr.A3267, PubMed 22976236
Up-regulation of NOTCH4 gene expression in bipolar disorder
Am J Psychiatry, 169 (12), 1292-300
DOI 10.1176/appi.ajp.2012.11091431, PubMed 23212060
Cardiovascular risk factors during second generation antipsychotic treatment are associated with increased C-reactive protein
Schizophr Res, 140 (1-3), 169-74
DOI 10.1016/j.schres.2012.06.040, PubMed 22817875
Diagnosis of dementia--automatic quantification of brain structures
Tidsskr Nor Laegeforen, 132 (15), 1747-51
DOI 10.4045/tidsskr.12.0148, PubMed 22929941
Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders
PLoS One, 7 (2), e31687
DOI 10.1371/journal.pone.0031687, PubMed 22384057
Risk factors related to lifetime suicide attempts in acutely admitted bipolar disorder inpatients
Bipolar Disord, 14 (7), 727-34
DOI 10.1111/bdi.12004, PubMed 22998124
Object relations and reality testing in schizophrenia, bipolar disorders, and healthy controls: differences in profiles and clinical correlates
Compr Psychiatry, 53 (8), 1200-7
DOI 10.1016/j.comppsych.2012.04.003, PubMed 22578986
Selective aggregation of self-disorders in first-treatment DSM-IV schizophrenia spectrum disorders
J Nerv Ment Dis, 200 (7), 632-6
DOI 10.1097/NMD.0b013e31825bfd6f, PubMed 22759943
Neurocognitive functioning in patients recently diagnosed with bipolar disorder
Bipolar Disord, 14 (3), 227-38
DOI 10.1111/j.1399-5618.2012.01004.x, PubMed 22548896
Executive function in early- and adult onset schizophrenia
Schizophr Res, 142 (1-3), 177-82
DOI 10.1016/j.schres.2012.10.006, PubMed 23102692
Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls
J Psychiatry Neurosci, 37 (1), 53-7
DOI 10.1503/jpn.100175, PubMed 21693093
DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder
PLoS One, 7 (4), e35424
DOI 10.1371/journal.pone.0035424, PubMed 22539971
Predictors of medication adherence in patients with schizophrenia and bipolar disorder
Acta Psychiatr Scand, 127 (1), 23-33
DOI 10.1111/j.1600-0447.2012.01911.x, PubMed 22900964
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
Nature, 488 (7409), 96-9
DOI 10.1038/nature11283, PubMed 22801501
Variant of TREM2 associated with the risk of Alzheimer's disease
N Engl J Med, 368 (2), 107-16
DOI 10.1056/NEJMoa1211103, PubMed 23150908
Lack of association between the regulator of G-protein signaling 4 (RGS4) rs951436 polymorphism and schizophrenia
Psychiatr Genet, 22 (5), 263-4
DOI 10.1097/YPG.0b013e32834f3558, PubMed 22157635
Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis
Am J Med Genet B Neuropsychiatr Genet, 159B (6), 722-30
DOI 10.1002/ajmg.b.32076, PubMed 22815203
Is there an optimal factor structure of the Positive and Negative Syndrome Scale in patients with first-episode psychosis?
Scand J Psychol, 54 (2), 160-5
DOI 10.1111/sjop.12017, PubMed 23252448
High prevalence of childhood trauma in patients with schizophrenia spectrum and affective disorder
Compr Psychiatry, 54 (2), 123-7
DOI 10.1016/j.comppsych.2012.06.009, PubMed 22901835
Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
Behav Brain Funct, 8, 24
DOI 10.1186/1744-9081-8-24, PubMed 22594806
Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways
Neuroimage, 70, 143-9
DOI 10.1016/j.neuroimage.2012.12.035, PubMed 23274185
Self-harm in patients with schizophrenia spectrum disorders
Arch Suicide Res, 16 (2), 111-23
DOI 10.1080/13811118.2012.667328, PubMed 22551042
Associations between variants near a monoaminergic pathways gene (PHOX2B) and amygdala reactivity: a genome-wide functional imaging study
Twin Res Hum Genet, 15 (3), 273-85
DOI 10.1017/thg.2012.5, PubMed 22856363
Effect of relevance on amygdala activation and association with the ventral striatum
Neuroimage, 62 (1), 95-101
DOI 10.1016/j.neuroimage.2012.04.035, PubMed 22546319
Schizophrenia patients with and without post-traumatic stress disorder (PTSD) have different mood symptom levels but same cognitive functioning
Acta Psychiatr Scand, 127 (6), 455-63
DOI 10.1111/acps.12041, PubMed 23176609
Cortical volume, surface area, and thickness in schizophrenia and bipolar disorder
Biol Psychiatry, 71 (6), 552-60
DOI 10.1016/j.biopsych.2011.11.026, PubMed 22281121
Cannabis use and premorbid functioning as predictors of poorer neurocognition in schizophrenia spectrum disorder
Schizophr Res, 143 (1), 84-9
DOI 10.1016/j.schres.2012.10.021, PubMed 23178107
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: no consistent evidence for an association in the Nordic population
Am J Med Genet B Neuropsychiatr Genet, 159B (8), 981-6
DOI 10.1002/ajmg.b.32104, PubMed 23076983
Identification of common variants associated with human hippocampal and intracranial volumes
Nat Genet, 44 (5), 552-61
DOI 10.1038/ng.2250, PubMed 22504417
Common variant at 16p11.2 conferring risk of psychosis
Mol Psychiatry, 19 (1), 108-14
DOI 10.1038/mp.2012.157, PubMed 23164818
Occupational functioning, symptoms and neurocognition in patients with psychotic disorders: investigating subgroups based on social security status
Soc Psychiatry Psychiatr Epidemiol, 48 (6), 863-74
DOI 10.1007/s00127-012-0598-2, PubMed 23064396
Factors associated with occupational and academic status in patients with first-episode psychosis with a particular focus on neurocognition
Soc Psychiatry Psychiatr Epidemiol, 47 (11), 1763-73
DOI 10.1007/s00127-012-0477-x, PubMed 22310699
Arousal Modulates Activity in the Medial Temporal Lobe during a Short-Term Relational Memory Task
Front Hum Neurosci, 5, 177
DOI 10.3389/fnhum.2011.00177, PubMed 22291626
Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder
Biol Psychiatry, 72 (8), 645-50
DOI 10.1016/j.biopsych.2012.02.040, PubMed 22560537
TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders
Transl Psychiatry, 2 (5), e112
DOI 10.1038/tp.2012.39, PubMed 22832956
Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?
Psychiatry Res, 198 (3), 495-500
DOI 10.1016/j.psychres.2011.12.045, PubMed 22472845
Publications 2011
Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia
Biol Psychiatry, 70 (7), 696-8
DOI 10.1016/j.biopsych.2011.02.034, PubMed 21514568
Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
Eur Neuropsychopharmacol, 21 (9), 700-4
DOI 10.1016/j.euroneuro.2010.12.008, PubMed 21295953
Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia
Arch Gen Psychiatry, 68 (8), 781-90
DOI 10.1001/archgenpsychiatry.2011.81, PubMed 21810643
Perceived discrimination is associated with severity of positive and depression/anxiety symptoms in immigrants with psychosis: a cross-sectional study
BMC Psychiatry, 11, 77
DOI 10.1186/1471-244X-11-77, PubMed 21548949
Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia
BMC Psychiatry, 11, 126
DOI 10.1186/1471-244X-11-126, PubMed 21812996
Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia
Psychiatr Genet, 21 (4), 214-5
DOI 10.1097/YPG.0b013e328341e020, PubMed 21712758
Evidence for impaired neocortical synaptic plasticity in bipolar II disorder
Biol Psychiatry, 71 (1), 68-74
DOI 10.1016/j.biopsych.2011.09.026, PubMed 22036034
The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder
J Affect Disord, 135 (1-3), 43-50
DOI 10.1016/j.jad.2011.08.006, PubMed 21880373
Verbal learning contributes to cognitive insight in schizophrenia independently of affective and psychotic symptoms
Prog Neuropsychopharmacol Biol Psychiatry, 35 (4), 1059-63
DOI 10.1016/j.pnpbp.2011.02.021, PubMed 21392553
At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia
Biol Psychiatry, 70 (1), 59-63
DOI 10.1016/j.biopsych.2011.01.031, PubMed 21414605
Brain cortical thickness and surface area correlates of neurocognitive performance in patients with schizophrenia, bipolar disorder, and healthy adults
J Int Neuropsychol Soc, 17 (6), 1080-93
DOI 10.1017/S1355617711001081, PubMed 22013998
Subcortical brain volumes relate to neurocognition in schizophrenia and bipolar disorder and healthy controls
Prog Neuropsychopharmacol Biol Psychiatry, 35 (4), 1122-30
DOI 10.1016/j.pnpbp.2011.03.014, PubMed 21457744
The association between anomalous self-experience and suicidality in first-episode schizophrenia seems mediated by depression
Compr Psychiatry, 53 (5), 456-60
DOI 10.1016/j.comppsych.2011.07.005, PubMed 21871617
The association between self-disorders and neurocognitive dysfunction in schizophrenia
Schizophr Res, 135 (1-3), 79-83
DOI 10.1016/j.schres.2011.11.015, PubMed 22137461
Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia
J Psychiatr Res, 45 (12), 1608-16
DOI 10.1016/j.jpsychires.2011.08.003, PubMed 21889167
The genetic structure of the Swedish population
PLoS One, 6 (8), e22547
DOI 10.1371/journal.pone.0022547, PubMed 21829632
The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia
Biol Psychiatry, 70 (1), 35-42
DOI 10.1016/j.biopsych.2011.01.030, PubMed 21439553
Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness
Am J Psychiatry, 168 (4), 408-17
DOI 10.1176/appi.ajp.2010.09111660, PubMed 21324950
Cognitive and clinical factors are associated with service engagement in early-phase schizophrenia spectrum disorders
J Nerv Ment Dis, 199 (3), 176-82
DOI 10.1097/NMD.0b013e31820bc2f9, PubMed 21346488
Combinations of SNPs related to signal transduction in bipolar disorder
PLoS One, 6 (8), e23812
DOI 10.1371/journal.pone.0023812, PubMed 21897858
Excessive cannabis use is associated with earlier age at onset in bipolar disorder
Eur Arch Psychiatry Clin Neurosci, 261 (6), 397-405
DOI 10.1007/s00406-011-0188-4, PubMed 21267743
Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function
J Psychiatr Res, 46 (2), 271-8
DOI 10.1016/j.jpsychires.2011.11.001, PubMed 22126837
Copy number variations in affective disorders and meta-analysis
Psychiatr Genet, 21 (6), 319-22
DOI 10.1097/YPG.0b013e3283463deb, PubMed 21451435
Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes
Genet Epidemiol, 35 (5), 318-32
DOI 10.1002/gepi.20580, PubMed 21484861
Severe social anxiety in early psychosis is associated with poor premorbid functioning, depression, and reduced quality of life
Compr Psychiatry, 53 (5), 434-40
DOI 10.1016/j.comppsych.2011.06.002, PubMed 21821242
Self-esteem is associated with premorbid adjustment and positive psychotic symptoms in early psychosis
BMC Psychiatry, 11, 136
DOI 10.1186/1471-244X-11-136, PubMed 21854599
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: a combined analysis of independent samples
Am J Med Genet B Neuropsychiatr Genet, 156 (2), 215-24
DOI 10.1002/ajmg.b.31160, PubMed 21302350
Despite clinical differences, bipolar disorder patients from acute wards and outpatient clinics have similar educational and disability levels compared to the general population
J Affect Disord, 132 (1-2), 209-15
DOI 10.1016/j.jad.2011.02.025, PubMed 21440307
Sex-specific cortisol levels in bipolar disorder and schizophrenia during mental challenge--relationship to clinical characteristics and medication
Prog Neuropsychopharmacol Biol Psychiatry, 35 (4), 1100-7
DOI 10.1016/j.pnpbp.2011.03.008, PubMed 21420462
Increased systemic cortisol metabolism in patients with schizophrenia and bipolar disorder: a mechanism for increased stress vulnerability?
J Clin Psychiatry, 72 (11), 1515-21
DOI 10.4088/JCP.10m06068yel, PubMed 21367348
Common variants at VRK2 and TCF4 conferring risk of schizophrenia
Hum Mol Genet, 20 (20), 4076-81
DOI 10.1093/hmg/ddr325, PubMed 21791550
Identification of low-frequency variants associated with gout and serum uric acid levels
Nat Genet, 43 (11), 1127-30
DOI 10.1038/ng.972, PubMed 21983786
Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples
Am J Med Genet B Neuropsychiatr Genet, 156B (8), 969-74
DOI 10.1002/ajmg.b.31244, PubMed 21972176
Prefrontal hyperactivation during a working memory task in early-onset schizophrenia spectrum disorders: an fMRI study
Psychiatry Res, 194 (3), 257-262
DOI 10.1016/j.pscychresns.2011.05.011, PubMed 22079661
Dual association of a TRKA polymorphism with schizophrenia
Psychiatr Genet, 21 (3), 125-31
DOI 10.1097/YPG.0b013e3283437194, PubMed 21317683
Sex differences in neuropsychological performance and social functioning in schizophrenia and bipolar disorder
Neuropsychology, 25 (4), 499-510
DOI 10.1037/a0022677, PubMed 21463042
Acta Neuropsychiatrica and Scandinavian College of Neuropsychopharmacology (SCNP)
Acta Neuropsychiatr, 23 (5), 199-200
DOI 10.1111/j.1601-5215.2011.00602.x, PubMed 28183387
Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders
Schizophr Bull, 38 (1), 15-22
DOI 10.1093/schbul/sbr113, PubMed 21908796
Publications 2010
Decreased self-reported arousal in schizophrenia during aversive picture viewing compared to bipolar disorder and healthy controls
Psychiatry Res, 185 (3), 309-14
DOI 10.1016/j.psychres.2010.07.026, PubMed 20724003
Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers
Psychiatry Res, 180 (2-3), 63-7
DOI 10.1016/j.psychres.2009.11.018, PubMed 20580984
Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
J Psychiatr Res, 44 (12), 748-53
DOI 10.1016/j.jpsychires.2010.02.002, PubMed 20185149
Intron 12 in NTRK3 is associated with bipolar disorder
Psychiatry Res, 185 (3), 358-62
DOI 10.1016/j.psychres.2010.05.011, PubMed 20554328
Suicidality in first episode psychosis is associated with insight and negative beliefs about psychosis
Schizophr Res, 123 (2-3), 257-62
DOI 10.1016/j.schres.2010.07.018, PubMed 20685083
Suicidality before and in the early phases of first episode psychosis
Schizophr Res, 119 (1-3), 11-7
DOI 10.1016/j.schres.2010.03.022, PubMed 20399077
Neurocognitive functioning and suicidality in schizophrenia spectrum disorders
Compr Psychiatry, 52 (2), 156-63
DOI 10.1016/j.comppsych.2010.06.001, PubMed 21295222
A cross-sectional study of vitamin D deficiency among immigrants and Norwegians with psychosis compared to the general population
J Clin Psychiatry, 71 (12), 1598-604
DOI 10.4088/JCP.09m05299yel, PubMed 20441728
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia
Mol Psychiatry, 16 (11), 1117-29
DOI 10.1038/mp.2010.96, PubMed 20838396
A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
J Affect Disord, 126 (1-2), 312-6
DOI 10.1016/j.jad.2010.04.007, PubMed 20451256
Apathy in first episode psychosis patients: one year follow up
Schizophr Res, 116 (1), 20-6
DOI 10.1016/j.schres.2009.10.014, PubMed 19948392
Investigating relationships between cortical thickness and cognitive performance in patients with schizophrenia and healthy adults
Psychiatry Res, 182 (2), 123-33
DOI 10.1016/j.pscychresns.2010.01.001, PubMed 20456929
An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes
Prog Neuropsychopharmacol Biol Psychiatry, 34 (7), 1259-65
DOI 10.1016/j.pnpbp.2010.07.001, PubMed 20638435
Validation of the Norwegian version of the Social Functioning Scale (SFS) for schizophrenia and bipolar disorder
Scand J Psychol, 51 (6), 525-33
DOI 10.1111/j.1467-9450.2010.00839.x, PubMed 20642739
Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: an association study
Schizophr Res, 127 (1-3), 270-2
DOI 10.1016/j.schres.2010.10.002, PubMed 21030213
Osteoprotegerin levels in patients with severe mental disorders
J Psychiatry Neurosci, 35 (5), 304-10
DOI 10.1503/jpn.090088, PubMed 20569643
The validity of d prime as a working memory index: results from the "Bergen n-back task"
J Clin Exp Neuropsychol, 32 (8), 871-80
DOI 10.1080/13803391003596421, PubMed 20383801
A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia
Hum Mol Genet, 19 (7), 1379-86
DOI 10.1093/hmg/ddq009, PubMed 20071346
Medication adherence in outpatients with severe mental disorders: relation between self-reports and serum level
J Clin Psychopharmacol, 30 (2), 169-75
DOI 10.1097/JCP.0b013e3181d2191e, PubMed 20520290
The study protocol of the Norwegian randomized controlled trial of electroconvulsive therapy in treatment resistant depression in bipolar disorder
BMC Psychiatry, 10, 16
DOI 10.1186/1471-244X-10-16, PubMed 20178636
Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area
Biol Psychiatry, 69 (1), 90-6
DOI 10.1016/j.biopsych.2010.07.035, PubMed 20950796
Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples
Am J Med Genet B Neuropsychiatr Genet, 153B (1), 86-96
DOI 10.1002/ajmg.b.30958, PubMed 19350560
Excessive substance use in bipolar disorder is associated with impaired functioning rather than clinical characteristics, a descriptive study
BMC Psychiatry, 10, 9
DOI 10.1186/1471-244X-10-9, PubMed 20105311
Treatment delay and excessive substance use in bipolar disorder
J Nerv Ment Dis, 198 (9), 628-33
DOI 10.1097/NMD.0b013e3181ef3ef4, PubMed 20823723
Impact of cognitive performance on the reproducibility of fMRI activation in schizophrenia
J Psychiatry Neurosci, 35 (6), 378-89
DOI 10.1503/jpn.090103, PubMed 20731962
The use of screening instruments for detecting alcohol and other drug use disorders in first-episode psychosis
Psychiatry Res, 177 (1-2), 228-34
DOI 10.1016/j.psychres.2010.01.007, PubMed 20178887
Cortical thickness and subcortical volumes in schizophrenia and bipolar disorder
Biol Psychiatry, 68 (1), 41-50
DOI 10.1016/j.biopsych.2010.03.036, PubMed 20609836
Depression and depressive symptoms in first episode psychosis
J Nerv Ment Dis, 198 (1), 67-71
DOI 10.1097/NMD.0b013e3181c81fc0, PubMed 20061872
Assessment of social anxiety in first episode psychosis using the Liebowitz Social Anxiety scale as a self-report measure
Eur Psychiatry, 26 (2), 115-21
DOI 10.1016/j.eurpsy.2010.08.014, PubMed 21036553
The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
Am J Med Genet B Neuropsychiatr Genet, 153B (2), 387-396
DOI 10.1002/ajmg.b.30991, PubMed 19526457
Bipolar disorder patients have similar levels of education but lower socio-economic status than the general population
J Affect Disord, 129 (1-3), 68-74
DOI 10.1016/j.jad.2010.08.012, PubMed 20832866
Psychosocial function in schizophrenia and bipolar disorder: Relationship to neurocognition and clinical symptoms
J Int Neuropsychol Soc, 16 (5), 771-83
DOI 10.1017/S1355617710000573, PubMed 20509984
SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders
Prog Neuropsychopharmacol Biol Psychiatry, 34 (8), 1500-6
DOI 10.1016/j.pnpbp.2010.08.013, PubMed 20800085
Expanding the range of ZNF804A variants conferring risk of psychosis
Mol Psychiatry, 16 (1), 59-66
DOI 10.1038/mp.2009.149, PubMed 20048749
Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample
Am J Med Genet B Neuropsychiatr Genet, 153B (7), 1276-82
DOI 10.1002/ajmg.b.31098, PubMed 20872766
Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
Am J Med Genet B Neuropsychiatr Genet, 153B (2), 610-618
DOI 10.1002/ajmg.b.31030, PubMed 19746410
Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls
Schizophr Res, 122 (1-3), 31-7
DOI 10.1016/j.schres.2010.05.007, PubMed 20605701
Publications 2009
Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia
Psychiatr Genet, 19 (5), 273-4
DOI 10.1097/YPG.0b013e32832a4fcd, PubMed 19491717
Hormonal markers of metabolic dysregulation in patients with severe mental disorders after olanzapine treatment under real-life conditions
J Clin Psychopharmacol, 29 (2), 109-16
DOI 10.1097/JCP.0b013e31819b95fc, PubMed 19512971
Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
Psychiatry Res, 168 (3), 256-8
DOI 10.1016/j.psychres.2008.08.007, PubMed 19223264
Delusions are associated with poor cognitive insight in schizophrenia
Schizophr Bull, 36 (4), 830-5
DOI 10.1093/schbul/sbn193, PubMed 19176474
Apathy is associated with executive functioning in first episode psychosis
BMC Psychiatry, 9, 1
DOI 10.1186/1471-244X-9-1, PubMed 19133132
Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor
Bipolar Disord, 11 (7), 726-34
DOI 10.1111/j.1399-5618.2009.00757.x, PubMed 19839997
Copy number variations of chromosome 16p13.1 region associated with schizophrenia
Mol Psychiatry, 16 (1), 17-25
DOI 10.1038/mp.2009.101, PubMed 19786961
A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations
Proc Natl Acad Sci U S A, 106 (36), 15483-8
DOI 10.1073/pnas.0901866106, PubMed 19717458
DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
Neuropsychobiology, 59 (3), 142-50
DOI 10.1159/000218076, PubMed 19439994
Age at onset of bipolar disorder in a Norwegian catchment area sample
J Affect Disord, 124 (1-2), 174-7
DOI 10.1016/j.jad.2009.10.031, PubMed 19931918
Age at onset of first episode and time to treatment in in-patients with bipolar disorder
Br J Psychiatry, 194 (6), 559-60
DOI 10.1192/bjp.bp.108.054452, PubMed 19478300
Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia
Neurobiol Dis, 34 (3), 518-24
DOI 10.1016/j.nbd.2009.03.011, PubMed 19344762
The impact of divergence time on the nature of population structure: an example from Iceland
PLoS Genet, 5 (6), e1000505
DOI 10.1371/journal.pgen.1000505, PubMed 19503599
Sex-dependent association of common variants of microcephaly genes with brain structure
Proc Natl Acad Sci U S A, 107 (1), 384-8
DOI 10.1073/pnas.0908454107, PubMed 20080800
Opposite relationships between cannabis use and neurocognitive functioning in bipolar disorder and schizophrenia
Psychol Med, 40 (8), 1337-47
DOI 10.1017/S0033291709991620, PubMed 19891810
Neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends on history of psychosis rather than diagnostic group
Schizophr Bull, 37 (1), 73-83
DOI 10.1093/schbul/sbp034, PubMed 19443616
Common variants conferring risk of schizophrenia
Nature, 460 (7256), 744-7
DOI 10.1038/nature08186, PubMed 19571808
No association between DGKH and bipolar disorder in a Scandinavian case-control sample
Psychiatr Genet, 19 (5), 269-72
DOI 10.1097/YPG.0b013e32832d302f, PubMed 19478689
Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia
J Psychiatr Res, 43 (15), 1195-9
DOI 10.1016/j.jpsychires.2009.04.006, PubMed 19435634
Using the Wisconsin Card Sorting Test to assess learning potential in normal IQ schizophrenia: does it have potential?
Nord J Psychiatry, 63 (5), 405-11
DOI 10.1080/08039480902879941, PubMed 19365785
Social problem-solving in high-functioning schizophrenia: specific deficits in sending skills
Psychiatry Res, 165 (3), 215-23
DOI 10.1016/j.psychres.2007.11.009, PubMed 19136154
No altered dorsal anterior cingulate activation in bipolar II disorder patients during a Go/No-go task: an fMRI study
Bipolar Disord, 11 (3), 270-9
DOI 10.1111/j.1399-5618.2009.00680.x, PubMed 19419384
Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
Neuropsychobiology, 60 (1), 31-6
DOI 10.1159/000235799, PubMed 19729970
Publications 2008
Dyslipidemia independent of body mass in antipsychotic-treated patients under real-life conditions
J Clin Psychopharmacol, 28 (2), 132-7
DOI 10.1097/JCP.0b013e318166c4f7, PubMed 18344722
A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE)
Schizophr Res, 107 (2-3), 242-8
DOI 10.1016/j.schres.2008.10.010, PubMed 19022628
Measurement of insight in patients with bipolar disorder: are self-rated scales developed for patients with schizophrenia applicable?
J Nerv Ment Dis, 196 (4), 333-5
DOI 10.1097/NMD.0b013e31816a62b2, PubMed 18414129
Beliefs about medications: measurement and relationship to adherence in patients with severe mental disorders
Acta Psychiatr Scand, 119 (1), 78-84
DOI 10.1111/j.1600-0447.2008.01279.x, PubMed 18983630
Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
Am J Med Genet B Neuropsychiatr Genet, 147B (6), 976-82
DOI 10.1002/ajmg.b.30671, PubMed 18165967
Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
Am J Med Genet B Neuropsychiatr Genet, 147B (7), 1089-100
DOI 10.1002/ajmg.b.30726, PubMed 18384059
Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples
Mol Psychiatry, 15 (5), 463-72
DOI 10.1038/mp.2008.110, PubMed 18936756
The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
BMC Med Genet, 9, 39
DOI 10.1186/1471-2350-9-39, PubMed 18460190
The human amygdala is involved in general behavioral relevance detection: evidence from an event-related functional magnetic resonance imaging Go-NoGo task
Neuroscience, 156 (3), 450-5
DOI 10.1016/j.neuroscience.2008.07.066, PubMed 18775476
The level of illicit drug use is related to symptoms and premorbid functioning in severe mental illness
Acta Psychiatr Scand, 118 (4), 297-304
DOI 10.1111/j.1600-0447.2008.01244.x, PubMed 18759810
Disruption of the neurexin 1 gene is associated with schizophrenia
Hum Mol Genet, 18 (5), 988-96
DOI 10.1093/hmg/ddn351, PubMed 18945720
Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample
Schizophr Res, 106 (2-3), 237-41
DOI 10.1016/j.schres.2008.08.024, PubMed 18818052
Neurocognitive profiles in bipolar I and bipolar II disorder: differences in pattern and magnitude of dysfunction
Bipolar Disord, 10 (2), 245-55
DOI 10.1111/j.1399-5618.2007.00492.x, PubMed 18271903
Large recurrent microdeletions associated with schizophrenia
Nature, 455 (7210), 232-6
DOI 10.1038/nature07229, PubMed 18668039
Emotion perception and learning potential: mediators between neurocognition and social problem-solving in schizophrenia?
J Int Neuropsychol Soc, 14 (2), 279-88
DOI 10.1017/S1355617708080314, PubMed 18282325
Can learning potential in schizophrenia be assessed with the standard CVLT-II? An exploratory study
Scand J Psychol, 49 (2), 179-86
DOI 10.1111/j.1467-9450.2008.00627.x, PubMed 18352988
Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients
Int J Neuropsychopharmacol, 11 (5), 679-84
DOI 10.1017/S1461145708008468, PubMed 18241359
Publications 2007
The level of cardiovascular risk factors in bipolar disorder equals that of schizophrenia: a comparative study
J Clin Psychiatry, 68 (6), 917-23
DOI 10.4088/jcp.v68n0614, PubMed 17592917
Measuring cognitive insight in schizophrenia and bipolar disorder: a comparative study
BMC Psychiatry, 7, 71
DOI 10.1186/1471-244X-7-71, PubMed 18072961
Psykiatriske forskningsmetoder
In Epidemiologiske og kliniske forskningsmetoder, Gyldendal akademisk, Oslo, [373]-[400]
BIBSYS 071650067
Brain expressed microRNAs implicated in schizophrenia etiology
PLoS One, 2 (9), e873
DOI 10.1371/journal.pone.0000873, PubMed 17849003
Differences in prevalence and patterns of substance use in schizophrenia and bipolar disorder
Psychol Med, 38 (9), 1241-9
DOI 10.1017/S003329170700236X, PubMed 18070373
Illicit drug use in patients with psychotic disorders compared with that in the general population: a cross-sectional study
Acta Psychiatr Scand, 117 (2), 133-8
DOI 10.1111/j.1600-0447.2007.01135.x, PubMed 18081921
The effect of gender on emotion perception in schizophrenia and bipolar disorder
Acta Psychiatr Scand, 116 (4), 263-70
DOI 10.1111/j.1600-0447.2007.00991.x, PubMed 17803756
Publications 2006
[Pharmacogenetics and tailored drug treatment in schizophrenia]
Tidsskr Nor Laegeforen, 126 (18), 2400-2
PubMed 16998555
Sociodemographic characteristics and cardiovascular risk factors in patients with severe mental disorders compared with the general population
J Clin Psychiatry, 67 (3), 425-33
DOI 10.4088/jcp.v67n0314, PubMed 16649830
Publications 2005
Should catatonia be part of the differential diagnosis of coma?
Nord J Psychiatry, 59 (6), 528-30
DOI 10.1080/08039480500360765, PubMed 16316908
Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease
J Neurochem, 95 (2), 553-62
DOI 10.1111/j.1471-4159.2005.03411.x, PubMed 16135087
Publications 2004
[Metabolic and cardiovascular adverse effects of modern antipsychotic agents]
Tidsskr Nor Laegeforen, 124 (2), 181-2
PubMed 14743232
Publications 2003
Oral dyskinesias and histopathological alterations in substantia nigra after long-term haloperidol treatment of old rats
Neuroscience, 122 (3), 717-25
DOI 10.1016/j.neuroscience.2003.08.058, PubMed 14622915
Memantine attenuates the increase in striatal preproenkephalin mRNA expression and development of haloperidol-induced persistent oral dyskinesias in rats
Brain Res, 994 (2), 188-92
DOI 10.1016/j.brainres.2003.09.035, PubMed 14642644
Publications 2002
Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression
Neurobiol Dis, 11 (3), 410-24
DOI 10.1006/nbdi.2002.0562, PubMed 12586550
[Schizophrenia and molecular genetics]
Tidsskr Nor Laegeforen, 122 (21), 2118-22
PubMed 12555650
Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid
Exp Neurol, 176 (1), 262-5
DOI 10.1006/exnr.2002.7933, PubMed 12093104
Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease
J Neurosci, 22 (5), 1592-9
DOI 10.1523/JNEUROSCI.22-05-01592.2002, PubMed 11880489
Reduced creatine kinase activity in transgenic amyotrophic lateral sclerosis mice
Free Radic Biol Med, 32 (9), 920-6
DOI 10.1016/s0891-5849(02)00784-0, PubMed 11978494
Publications 2001
Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease
Neurobiol Dis, 8 (3), 479-91
DOI 10.1006/nbdi.2001.0406, PubMed 11447996
Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice
Exp Neurol, 168 (2), 419-24
DOI 10.1006/exnr.2001.7633, PubMed 11259130
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP
Exp Neurol, 167 (1), 189-95
DOI 10.1006/exnr.2000.7525, PubMed 11161607
Lipoic acid improves survival in transgenic mouse models of Huntington's disease
Neuroreport, 12 (15), 3371-3
DOI 10.1097/00001756-200110290-00044, PubMed 11711888
Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease
Ann Neurol, 50 (1), 112-7
DOI 10.1002/ana.1085, PubMed 11456300
Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid
Exp Neurol, 168 (2), 356-63
DOI 10.1006/exnr.2001.7627, PubMed 11259123
Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation
J Neurochem, 77 (2), 383-90
DOI 10.1046/j.1471-4159.2001.00188.x, PubMed 11299300
Oral dyskinesias and morphological changes in rat striatum during long-term haloperidol administration
Psychopharmacology (Berl), 157 (1), 11-9
DOI 10.1007/s002130100767, PubMed 11512038
Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease
J Neurochem, 79 (6), 1246-9
DOI 10.1046/j.1471-4159.2001.00689.x, PubMed 11752065
Publications 2000
N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis
Neuroreport, 11 (11), 2491-3
DOI 10.1097/00001756-200008030-00029, PubMed 10943709
Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant
J Neurochem, 75 (2), 847-52
DOI 10.1046/j.1471-4159.2000.0750847.x, PubMed 10899963
Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis
Ann Neurol, 47 (4), 447-55
PubMed 10762155
Reduced number of striatal neurons expressing preprosomatostatin mRNA in rats with oral dyskinesias after long-term haloperidol administration
Neurosci Lett, 279 (1), 21-4
DOI 10.1016/s0304-3940(99)00939-8, PubMed 10670778
Neurotoxicity associated with neuroleptic-induced oral dyskinesias in rats. Implications for tardive dyskinesia?
Prog Neurobiol, 61 (5), 525-41
DOI 10.1016/s0301-0082(99)00064-7, PubMed 10748322
Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease
J Neurosci, 20 (12), 4389-97
DOI 10.1523/JNEUROSCI.20-12-04389.2000, PubMed 10844007
Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice
J Neurochem, 74 (5), 2108-19
DOI 10.1046/j.1471-4159.2000.0742108.x, PubMed 10800956
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
J Neurosci, 20 (1), 1-7
DOI 10.1523/JNEUROSCI.20-01-00001.2000, PubMed 10627575
Inhibition of neuronal nitric oxide synthase protects against MPTP toxicity
Neuroreport, 11 (6), 1265-8
DOI 10.1097/00001756-200004270-00024, PubMed 10817604
No changes in dopamine D(1) receptor mRNA expressing neurons in the dorsal striatum of rats with oral movements induced by long-term haloperidol administration
Brain Res, 859 (2), 394-7
DOI 10.1016/s0006-8993(00)02017-5, PubMed 10719094
Publications 1999
The relationship between oral dyskinesias produced by long-term haloperidol treatment, the density of striatal preproenkephalin messenger RNA and enkephalin peptide, and the number of striatal neurons expressing preproenkephalin messenger RNA in rats
Neuroscience, 88 (1), 27-35
DOI 10.1016/s0306-4522(98)00175-4, PubMed 10051187
Coenzyme Q10 does not prevent oral dyskinesias induced by long-term haloperidol treatment of rats
Pharmacol Biochem Behav, 64 (3), 637-42
DOI 10.1016/s0091-3057(99)00118-5, PubMed 10548281
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
Nat Med, 5 (3), 347-50
DOI 10.1038/6568, PubMed 10086395
Publications 1998
Oral Dyskinesias and striatal lesions in rats after long-term co-treatment with haloperidol and 3-nitropropionic acid
Neuroscience, 87 (3), 639-48
DOI 10.1016/s0306-4522(98)00160-2, PubMed 9758230
Mice deficient in group IV cytosolic phospholipase A2 are resistant to MPTP neurotoxicity
J Neurochem, 71 (6), 2634-7
DOI 10.1046/j.1471-4159.1998.71062634.x, PubMed 9832165
Publications 1997
Non-functional CYP2D6 alleles and risk for neuroleptic-induced movement disorders in schizophrenic patients
Psychopharmacology (Berl), 131 (2), 174-9
DOI 10.1007/s002130050281, PubMed 9201806
Publications 1996
Inhibition by memantine of the development of persistent oral dyskinesias induced by long-term haloperidol treatment of rats
Br J Pharmacol, 119 (4), 751-7
DOI 10.1111/j.1476-5381.1996.tb15736.x, PubMed 8904651
Characterization and PCR-based detection of two different hybrid CYP2D7P/CYP2D6 alleles associated with the poor metabolizer phenotype
Pharmacogenetics, 6 (4), 319-28
DOI 10.1097/00008571-199608000-00005, PubMed 8873218
Correlation of vacuous chewing movements with morphological changes in rats following 1-year treatment with haloperidol
Psychopharmacology (Berl), 125 (3), 238-47
DOI 10.1007/BF02247334, PubMed 8815959
Estimation of the number of somatostatin neurons in the striatum: an in situ hybridization study using the optical fractionator method
J Comp Neurol, 370 (1), 11-22
DOI 10.1002/(SICI)1096-9861(19960617)370:1<11::AID-CNE2>3.0.CO;2-O, PubMed 8797153
Publications 1995
The rat model of tardive dyskinesia: relationship between vacuous chewing movements and gross motor activity during acute and long-term haloperidol treatment
Life Sci, 57 (24), 2263-72
DOI 10.1016/0024-3205(95)02219-9, PubMed 7475980
The mitochondrial toxin 3-nitropropionic acid induces vacuous chewing movements in rats. Implications for tardive dyskinesia?
Psychopharmacology (Berl), 119 (4), 474-6
DOI 10.1007/BF02245864, PubMed 7480528
Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology
Pharmacogenetics, 5 (4), 215-23
DOI 10.1097/00008571-199508000-00005, PubMed 8528268
Publications 1994
GM1 ganglioside attenuates the development of vacuous chewing movements induced by long-term haloperidol treatment of rats
Psychopharmacology (Berl), 116 (4), 517-22
DOI 10.1007/BF02247487, PubMed 7701057
Tardive dyskinesia: behavioral effects of repeated intracerebroventricular haloperidol injections in rats do not confirm the kindling hypothesis
Pharmacol Biochem Behav, 49 (2), 309-12
DOI 10.1016/0091-3057(94)90426-x, PubMed 7824543
The relationship between motor effects in rats following acute and chronic haloperidol treatment
Psychopharmacology (Berl), 116 (1), 89-92
DOI 10.1007/BF02244876, PubMed 7862936