Qian Peng

  • Senior scientist Dr. med.
 

Publications 2019

Theodossiou TA, Ali M, Grigalavicius M, Grallert B, Dillard P, Schink KO, Olsen CE, Wälchli S, Inderberg EM, Kubin A, Peng Q, Berg K (2019)
Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
NPJ Breast Cancer, 5, 13
DOI 10.1038/s41523-019-0108-8, PubMed 30993194

Publications 2018

Holien T, Gederaas OA, Darvekar SR, Christensen E, Peng Q (2018)
Comparison between 8-methoxypsoralen and 5-aminolevulinic acid in killing T cells of photopheresis patients ex vivo
Lasers Surg Med, 50 (5), 469-475
DOI 10.1002/lsm.22806, PubMed 29460964

Madsen SJ, Christie C, Huynh K, Peng Q, Uzal FA, Krasieva TB, Hirschberg H (2018)
Limiting glioma development by photodynamic therapy-generated macrophage vaccine and allo-stimulation: an in vivo histological study in rats
J Biomed Opt, 23 (2), 1-7
DOI 10.1117/1.JBO.23.2.028001, PubMed 29417766

Marzioch J, Kieninger J, Weltin A, Flamm H, Aravindalochanan K, Sandvik JA, Pettersen EO, Peng Q, Urban GA (2018)
On-chip photodynamic therapy - monitoring cell metabolism using electrochemical microsensors
Lab Chip, 18 (22), 3353-3360
DOI 10.1039/c8lc00799c, PubMed 30310892

Nair RK, Christie C, Ju D, Shin D, Pomeroy A, Berg K, Peng Q, Hirschberg H (2018)
Enhancing the effects of chemotherapy by combined macrophage-mediated photothermal therapy (PTT) and photochemical internalization (PCI)
Lasers Med Sci, 33 (8), 1747-1755
DOI 10.1007/s10103-018-2534-5, PubMed 29802587

Nitulescu GM, Van De Venter M, Nitulescu G, Ungurianu A, Juzenas P, Peng Q, Olaru OT, Grădinaru D, Tsatsakis A, Tsoukalas D, Spandidos DA, Margina D (2018)
The Akt pathway in oncology therapy and beyond (Review)
Int J Oncol, 53 (6), 2319-2331
DOI 10.3892/ijo.2018.4597, PubMed 30334567

Sioud M, Westby P, Vasovic V, Fløisand Y, Peng Q (2018)
Development of a new high-affinity human antibody with antitumor activity against solid and blood malignancies
FASEB J, 32 (9), 5063-5077
DOI 10.1096/fj.201701544R, PubMed 29913558

Weyergang A, Fremstedal AS, Skarpen E, Peng Q, Mohamedali KA, Eng MS, Cheung LH, Rosenblum MG, Waltenberger J, Berg K (2018)
Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy
J Control Release, 288, 161-172
DOI 10.1016/j.jconrel.2018.09.005, PubMed 30217739

Publications 2017

Christie C, Madsen SJ, Peng Q, Hirschberg H (2017)
Photothermal Therapy Employing Gold Nanoparticle- Loaded Macrophages as Delivery Vehicles: Comparing the Efficiency of Nanoshells Versus Nanorods
J Environ Pathol Toxicol Oncol, 36 (3), 229-235
DOI 10.1615/JEnvironPatholToxicolOncol.2017021545, PubMed 29283336

Ning S, Kang Q, Fan D, Liu J, Xue C, Zhang X, Ding C, Zhang J, Peng Q, Ji Z (2017)
Protein 4.1R is Involved in the Transport of 5-Aminolevulinic Acid by Interaction with GATs in MEF Cells
Photochem Photobiol, 94 (1), 173-178
DOI 10.1111/php.12842, PubMed 28881432

Sellevold S, Peng Q, Fremstedal ASV, Berg K (2017)
Photochemical internalization (PCI) of bleomycin is equally effective in two dissimilar leiomyosarcoma xenografts in athymic mice
Photodiagnosis Photodyn Ther, 20, 95-106
DOI 10.1016/j.pdpdt.2017.08.015, PubMed 28865875

Publications 2016

Christie CE, Peng Q, Madsen SJ, Uzal FA, Hirschberg H (2016)
Increasing the efficacy of antitumor glioma vaccines by photodynamic therapy and local injection of allogeneic glioma cells
PROC SPIE, 9690, UNSP 96900D

Li X, Zhong Y, Lu J, Axcrona K, Eide L, Syljuåsen RG, Peng Q, Wang J, Zhang H, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2016)
MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
Oncotarget, 7 (26), 40297-40313
DOI 10.18632/oncotarget.9610, PubMed 27248169

Madsen SJ, Shih EC, Peng Q, Christie C, Krasieva T, Hirschberg H (2016)
Photothermal enhancement of chemotherapy mediated by gold-silica nanoshell-loaded macrophages: in vitro squamous cell carcinoma study
J Biomed Opt, 21 (1), 18004
DOI 10.1117/1.JBO.21.1.018004, PubMed 26811077

Marzioch J, Kieninger J, Sandvik JA, Pettersen EO, Peng Q, Urban G (2016)
Electrochemical microsensor system for cancer research on photodynamic therapy in vitro
J PHYS CONF SER, 757, UNSP 012002

Mobergslien A, Peng Q, Vasovic V, Sioud M (2016)
Cancer cell-binding peptide fused Fc domain activates immune effector cells and blocks tumor growth
Oncotarget, 7 (46), 75940-75953
DOI 10.18632/oncotarget.12445, PubMed 27713158

Publications 2015

Baglo Y, Peng Q, Hagen L, Berg K, Høgset A, Drabløs F, Gederaas OA (2015)
Studies of the photosensitizer disulfonated meso-tetraphenyl chlorin in an orthotopic rat bladder tumor model
Photodiagnosis Photodyn Ther, 12 (1), 58-66
DOI 10.1016/j.pdpdt.2014.12.005, PubMed 25575731

Berstad MB, Cheung LH, Berg K, Peng Q, Fremstedal AS, Patzke S, Rosenblum MG, Weyergang A (2015)
Design of an EGFR-targeting toxin for photochemical delivery: in vitro and in vivo selectivity and efficacy
Oncogene, 34 (44), 5582-92
DOI 10.1038/onc.2015.15, PubMed 25684137

Bostad M, Olsen CE, Peng Q, Berg K, Høgset A, Selbo PK (2015)
Light-controlled endosomal escape of the novel CD133-targeting immunotoxin AC133-saporin by photochemical internalization - A minimally invasive cancer stem cell-targeting strategy
J Control Release, 206, 37-48
DOI 10.1016/j.jconrel.2015.03.008, PubMed 25758331

Bull-Hansen B, Berstad MB, Berg K, Cao Y, Skarpen E, Fremstedal AS, Rosenblum MG, Peng Q, Weyergang A (2015)
Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer
Oncotarget, 6 (14), 12436-51
DOI 10.18632/oncotarget.3814, PubMed 26002552

Christie C, Madsen SJ, Peng Q, Hirschberg H (2015)
Macrophages as nanoparticle delivery vectors for photothermal therapy of brain tumors
Ther Deliv, 6 (3), 371-84
DOI 10.4155/tde.14.121, PubMed 25853311

Helgesen AL, Warloe T, Pripp AH, Kirschner R, Peng Q, Tanbo T, Gjersvik P (2015)
Vulvovaginal photodynamic therapy vs. topical corticosteroids in genital erosive lichen planus: a randomized controlled trial
Br J Dermatol, 173 (5), 1156-62
DOI 10.1111/bjd.14033, PubMed 26189484

Hirschberg H, Trinidad A, Christie CE, Kwon YJ, Peng Q, Madsen SJ (2015)
Combined concurrent nanoshell loaded macrophage-mediated photothermal and photodynamic therapies
PROC SPIE, 9303, 930322

Madsen SJ, Christie C, Hong SJ, Trinidad A, Peng Q, Uzal FA, Hirschberg H (2015)
Nanoparticle-loaded macrophage-mediated photothermal therapy: potential for glioma treatment
Lasers Med Sci, 30 (4), 1357-65
DOI 10.1007/s10103-015-1742-5, PubMed 25794592

Marzioch J, Kieninger J, Sandvik JA, Pettersen EO, Peng Q, Urban G (2015)
Photodynamic Therapy - In Vitro Investigation Using an Electrochemical Microsensor System
PROCEDIA ENGINEER, 120, 468-471

Mobergslien A, Vasovic V, Mathiesen G, Fredriksen L, Westby P, Eijsink VG, Peng Q, Sioud M (2015)
Recombinant Lactobacillus plantarum induces immune responses to cancer testis antigen NY-ESO-1 and maturation of dendritic cells
Hum Vaccin Immunother, 11 (11), 2664-73
DOI 10.1080/21645515.2015.1056952, PubMed 26185907

Nitulescu GM, Margina D, Juzenas P, Peng Q, Olaru OT, Saloustros E, Fenga C, Spandidos DΑ, Libra M, Tsatsakis AM (2015)
Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)
Int J Oncol, 48 (3), 869-85
DOI 10.3892/ijo.2015.3306, PubMed 26698230

Publications 2014

Cunderlíková B, Vasovič V, Randeberg LL, Christensen E, Warloe T, Nesland JM, Peng Q (2014)
Modification of extracorporeal photopheresis technology with porphyrin precursors. Comparison between 8-methoxypsoralen and hexaminolevulinate in killing human T-cell lymphoma cell lines in vitro
Biochim Biophys Acta, 1840 (9), 2702-8
DOI 10.1016/j.bbagen.2014.05.020, PubMed 24915603

Helgesen AL, Gjersvik P, Peng Q, Vasovic V, Pripp AH, Jebsen P, Tanbo T, Warloe T (2014)
Biodistribution of protoporphyrin IX in female genital erosive lichen planus after topical application of hexaminolevulinate
Photodiagnosis Photodyn Ther, 11 (2), 113-7
DOI 10.1016/j.pdpdt.2014.01.005, PubMed 24530993

Trinidad AJ, Hong SJ, Peng Q, Madsen SJ, Hirschberg H (2014)
Combined concurrent photodynamic and gold nanoshell loaded macrophage-mediated photothermal therapies: an in vitro study on squamous cell head and neck carcinoma
Lasers Surg Med, 46 (4), 310-8
DOI 10.1002/lsm.22235, PubMed 24648368

Weyergang A, Cheung LH, Rosenblum MG, Mohamedali KA, Peng Q, Waltenberger J, Berg K (2014)
Photochemical internalization augments tumor vascular cytotoxicity and specificity of VEGF(121)/rGel fusion toxin
J Control Release, 180, 1-9
DOI 10.1016/j.jconrel.2014.02.003, PubMed 24531010

Publications 2013

Cunderlíková B, Peng Q, Mateasík A (2013)
Factors implicated in the assessment of aminolevulinic acid-induced protoporphyrin IX fluorescence
Biochim Biophys Acta, 1830 (3), 2750-62
DOI 10.1016/j.bbagen.2012.10.023, PubMed 23142760

Madsen SJ, Gach HM, Hong SJ, Uzal FA, Peng Q, Hirschberg H (2013)
Increased nanoparticle-loaded exogenous macrophage migration into the brain following PDT-induced blood-brain barrier disruption
Lasers Surg Med, 45 (8), 524-32
DOI 10.1002/lsm.22172, PubMed 24037939

Shahzidi S, Brech A, Sioud M, Li X, Suo Z, Nesland JM, Peng Q (2013)
Lamin A/C cleavage by caspase-6 activation is crucial for apoptotic induction by photodynamic therapy with hexaminolevulinate in human B-cell lymphoma cells
Cancer Lett, 339 (1), 25-32
DOI 10.1016/j.canlet.2013.07.026, PubMed 23916608

Wu X, Chen JY, Brech A, Fang C, Wang J, Helm PJ, Peng Q (2013)
The use of femto-second lasers to trigger powerful explosions of gold nanorods to destroy cancer cells
Biomaterials, 34 (26), 6157-62
DOI 10.1016/j.biomaterials.2013.04.048, PubMed 23706782

Publications 2011

Shahzidi S, Cunderlíková B, Więdłocha A, Zhen Y, Vasovič V, Nesland JM, Peng Q (2011)
Simultaneously targeting mitochondria and endoplasmic reticulum by photodynamic therapy induces apoptosis in human lymphoma cells
Photochem Photobiol Sci, 10 (11), 1773-82
DOI 10.1039/c1pp05169e, PubMed 21881674

Zhao JF, Chen JY, Mi L, Wang PN, Peng Q (2011)
Enhancement of intracellular delivery of anti-cancer drugs by the Tat peptide
Ultrastruct Pathol, 35 (3), 119-23
DOI 10.3109/01913123.2011.557522, PubMed 21405950

Zheng S, Chen JY, Wang JY, Zhou LW, Peng Q (2011)
Effects of cell cycle on the uptake of water soluble quantum dots by cells
J. Appl. Phys., 110 (12), 124701

Publications 2010

Čunderlíková B, Vasovič V, Sieber F, Furre T, Borgen E, Nesland JM, Peng Q (2010)
Hexaminolevulinate-mediated photodynamic purging of marrow grafts with murine breast carcinoma
Bone Marrow Transplant, 46 (8), 1118-27
DOI 10.1038/bmt.2010.277, PubMed 21057550

Čunderlíková B, Vasovič V, Sieber F, Furre T, Nesland JM, Peng Q (2010)
Hexaminolevulinate-mediated photodynamic purging of leukemia cells from BM
Bone Marrow Transplant, 45 (10), 1553-61
DOI 10.1038/bmt.2009.382, PubMed 20118993

Li L, Chen JY, Wu X, Wang PN, Peng Q (2010)
Plasmonic gold nanorods can carry sulfonated aluminum phthalocyanine to improve photodynamic detection and therapy of cancers
J Phys Chem B, 114 (51), 17194-200
DOI 10.1021/jp109363n, PubMed 21138283

Publications 2009

Furre IE, Nesland JM, Peng Q (2009)
Apoptotic induction by photodynamic therapy using Hexaminolevulinate with a literature review
PROC SPIE, 7380, 73800X

Hirschberg H, Peng Q, Uzal FA, Chighvinadze D, Zhang MJ, Madsen SJ (2009)
Targeted opening of the blood brain barrier by ALA mediated photodynamic therapy
PROC SPIE, 7380, 73801C

Hirschberg H, Zhang MJ, Gach HM, Uzal FA, Peng Q, Sun CH, Chighvinadze D, Madsen SJ (2009)
Targeted delivery of bleomycin to the brain using photo-chemical internalization of Clostridium perfringens epsilon prototoxin
J Neurooncol, 95 (3), 317-329
DOI 10.1007/s11060-009-9930-4, PubMed 19506813

Weyergang A, Berg K, Kaalhus O, Peng Q, Selbo PK (2009)
Photodynamic therapy targets the mTOR signaling network in vitro and in vivo
Mol Pharm, 6 (1), 255-64
DOI 10.1021/mp800156e, PubMed 19125612

Woodhams J, Lou PJ, Selbo PK, Mosse A, Oukrif D, MacRobert A, Novelli M, Peng Q, Berg K, Bown SG (2009)
Intracellular re-localisation by photochemical internalisation enhances the cytotoxic effect of gelonin--quantitative studies in normal rat liver
J Control Release, 142 (3), 347-53
DOI 10.1016/j.jconrel.2009.11.017, PubMed 19932724

Zhang Y, Mi L, Xiong R, Wang PN, Chen JY, Yang W, Wang C, Peng Q (2009)
Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells
Nanoscale Res Lett, 4 (7), 606-12
DOI 10.1007/s11671-009-9307-9, PubMed 20596411

Publications 2008

Collaud S, Peng Q, Gurny R, Lange N (2008)
Thermosetting gel for the delivery of 5-aminolevulinic acid esters to the cervix
J Pharm Sci, 97 (7), 2680-90
DOI 10.1002/jps.21181, PubMed 17828758

Hirschberg H, Uzal FA, Chighvinadze D, Zhang MJ, Peng Q, Madsen SJ (2008)
Disruption of the blood-brain barrier following ALA-mediated photodynamic therapy
Lasers Surg Med, 40 (8), 535-42
DOI 10.1002/lsm.20670, PubMed 18798293

Lu S, Chen JY, Zhang Y, Ma J, Wang PN, Peng Q (2008)
Fluorescence detection of protoporphyrin IX in living cells: a comparative study on single- and two-photon excitation
J Biomed Opt, 13 (2), 024014
DOI 10.1117/1.2907316, PubMed 18465977

Norum OJ, Gaustad JV, Angell-Petersen E, Rofstad EK, Peng Q, Giercksky KE, Berg K (2008)
Photochemical internalization of bleomycin is superior to photodynamic therapy due to the therapeutic effect in the tumor periphery
Photochem Photobiol, 85 (3), 740-9
DOI 10.1111/j.1751-1097.2008.00477.x, PubMed 19076314

Peng Q, Juzeniene A, Chen J, Svaasand LO, Warloe T, Giercksky KE, Moan J (2008)
Lasers in medicine
Rep. Prog. Phys., 71 (5), 056701

Wang T, Chen JY, Zhen S, Wang PN, Wang CC, Yang WL, Peng Q (2008)
Thiol-capped CdTe quantum dots with two-photon excitation for imaging high autofluorescence background living cells
J Fluoresc, 19 (4), 615-21
DOI 10.1007/s10895-008-0452-9, PubMed 19104920

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