Morten Pedersen Oksvold
- Scientist; PhD
- (+47) 22781424
Mini CV:
Education:
2004 PhD (Dr. Philos), University of Oslo. Thesis: Trafficking of and signaling from the epidermal growth factor receptor after ligand and stress exposure.
1996 Ms, University of Oslo. Title: A morphological and kinetic study of large vesicular structures in MDCK cells transfected with invariant chain
Research interests:
Trafficking of and signaling from BMP/TGF-beta receptors in B-cell lymphoma
Intracellular localization of signaling molecules down stream of BMP/TGF-beta
receptors
Confocal immunofluorescence microscopy combined with flow cytometry
Previous employment:
2004-2007 Post doc, Institute of Pathology, Rikshospitalet University Hospital, University of Oslo.
Publications 2021
Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
Sci Rep, 11 (1), 6317
DOI 10.1038/s41598-021-85613-8, PubMed 33737576
Publications 2020
Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis
Cancers (Basel), 12 (2)
DOI 10.3390/cancers12020377, PubMed 32041351
Publications 2018
Artesunate shows potent anti-tumor activity in B-cell lymphoma
J Hematol Oncol, 11 (1), 23
DOI 10.1186/s13045-018-0561-0, PubMed 29458389
Publications 2017
BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5
PLoS One, 12 (5), e0177188
DOI 10.1371/journal.pone.0177188, PubMed 28489883
Human c-SRC kinase (CSK) overexpression makes T cells dummy
Cancer Immunol Immunother, 67 (4), 525-536
DOI 10.1007/s00262-017-2105-9, PubMed 29248956
Publications 2015
Incidence of Data Duplications in a Randomly Selected Pool of Life Science Publications
Sci Eng Ethics, 22 (2), 487-96
DOI 10.1007/s11948-015-9668-7, PubMed 26065681
The targeting of human and mouse B lymphocytes by dasatinib
Exp Hematol, 43 (5), 352-363.e4
DOI 10.1016/j.exphem.2015.01.008, PubMed 25641047
Magnetic bead-based isolation of exosomes
Methods Mol Biol, 1218, 465-81
DOI 10.1007/978-1-4939-1538-5_27, PubMed 25319668
Publications 2014
Expression of B-cell surface antigens in subpopulations of exosomes released from B-cell lymphoma cells
Clin Ther, 36 (6), 847-862.e1
DOI 10.1016/j.clinthera.2014.05.010, PubMed 24952935
Publications 2012
SARA is dispensable for functional TGF-β signaling
FEBS Lett, 586 (19), 3367-72
DOI 10.1016/j.febslet.2012.07.027, PubMed 22819827
Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma
PLoS One, 7 (10), e46117
DOI 10.1371/journal.pone.0046117, PubMed 23049692
Effect of cycloheximide on epidermal growth factor receptor trafficking and signaling
FEBS Lett, 586 (20), 3575-81
DOI 10.1016/j.febslet.2012.08.022, PubMed 22971756
Publications 2011
Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7
Eur J Immunol, 41 (11), 3135-45
DOI 10.1002/eji.201141558, PubMed 21898381
Publications 2010
TGF-β-induced growth inhibition in B-cell lymphoma correlates with Smad1/5 signalling and constitutively active p38 MAPK
BMC Immunol, 11, 57
DOI 10.1186/1471-2172-11-57, PubMed 21092277
Flere gullkorn fra pasientjournalen: morsomme sitater fra pasientjournalen, doktorskolen og pasienter
Gyldendal, [Oslo], 136 s.
BIBSYS 100829643, ISBN 978-82-05-39776-7
Publications 2008
Gullkorn fra pasientjournalen
Gyldendal litteratur, [Oslo], 136 s.
BIBSYS 082330158, ISBN 978-82-05-38463-7
Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit
BMC Cell Biol, 9, 16
DOI 10.1186/1471-2121-9-16, PubMed 18380891
Distinct functions of H-Ras and K-Ras in proliferation and survival of primary hepatocytes due to selective activation of ERK and PI3K
J Cell Physiol, 215 (3), 818-26
DOI 10.1002/jcp.21367, PubMed 18163378
Publications 2007
The Cbl-b RING finger domain has a limited role in regulating inflammatory cytokine production by IgE-activated mast cells
Mol Immunol, 45 (4), 925-36
DOI 10.1016/j.molimm.2007.08.002, PubMed 17868870
MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments
FASEB J, 22 (2), 466-76
DOI 10.1096/fj.07-8650com, PubMed 17928366
CDK2 regulation through PI3K and CDK4 is necessary for cell cycle progression of primary rat hepatocytes
Cell Prolif, 40 (4), 475-87
DOI 10.1111/j.1365-2184.2007.00451.x, PubMed 17635516
Activation of the p53-p21(Cip1) pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes
Oncogene, 27 (19), 2763-71
DOI 10.1038/sj.onc.1210937, PubMed 18026139
Publications 2005
Subtype-specific sorting of the ETA endothelin receptor by a novel endocytic recycling signal for G protein-coupled receptors
Mol Pharmacol, 67 (5), 1581-90
DOI 10.1124/mol.104.007013, PubMed 15713850
Cytoplasmic retention of peroxide-activated ERK provides survival in primary cultures of rat hepatocytes
Hepatology, 42 (1), 200-7
DOI 10.1002/hep.20762, PubMed 15962331
Altered regulation of EGF receptor signaling following a partial hepatectomy
J Cell Physiol, 202 (3), 707-16
DOI 10.1002/jcp.20171, PubMed 15389569
Publications 2004
Trafficking of and signaling from the epidermal growth factor receptor after ligand and stress exposure
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 155, 1 b. (flere pag.)
BIBSYS 04023956x, ISBN 82-8072-097-9
Identification of 14-3-3zeta as an EGF receptor interacting protein
FEBS Lett, 569 (1-3), 207-10
DOI 10.1016/j.febslet.2004.05.068, PubMed 15225635
UV-radiation-induced internalization of the epidermal growth factor receptor requires distinct serine and tyrosine residues in the cytoplasmic carboxy-terminal domain
Radiat Res, 161 (6), 685-91
DOI 10.1667/rr3185, PubMed 15161351
Publications 2003
Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor
Oncogene, 22 (52), 8509-18
DOI 10.1038/sj.onc.1207117, PubMed 14627991
Publications 2002
Localizing the EGF receptor
Nat Cell Biol, 4 (2), E22; author reply E22-3
DOI 10.1038/ncb0202-e22a, PubMed 11835048
UV induces tyrosine kinase-independent internalisation and endosome arrest of the EGF receptor
J Cell Sci, 115 (Pt 4), 793-803
DOI 10.1242/jcs.115.4.793, PubMed 11865035
Fluorescent histochemical techniques for analysis of intracellular signaling
J Histochem Cytochem, 50 (3), 289-303
DOI 10.1177/002215540205000301, PubMed 11850432
Publications 2001
Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF
Eur J Cell Biol, 80 (4), 285-94
DOI 10.1078/0171-9335-00160, PubMed 11370743
Publications 2000
The carcinogen 2-acetylaminofluorene inhibits activation and nuclear accumulation of cyclin-dependent kinase 2 in growth-induced rat liver
Mol Carcinog, 27 (3), 190-9
DOI 10.1002/(SICI)1098-2744(200003)27:3<190::AID-MC6>3.3.CO;2-E, PubMed 10708481
Immunocytochemical localization of Shc and activated EGF receptor in early endosomes after EGF stimulation of HeLa cells
J Histochem Cytochem, 48 (1), 21-33
DOI 10.1177/002215540004800103, PubMed 10653583
Impaired nuclear accumulation and shortened phosphorylation of ERK after growth factor stimulation in cultured hepatocytes from rats exposed to 2-acetylaminofluorene
Mol Carcinog, 28 (2), 84-96
DOI 10.1002/1098-2744(200006)28:2<84::aid-mc4>3.0.co;2-x, PubMed 10900465
Publications 1999
[Why is dioxin harmful?]
Tidsskr Nor Laegeforen, 119 (29), 4323-8
PubMed 10667131
Publications 1998
Ribosomal protein insufficiency and the minute syndrome in Drosophila: a dose-response relationship
Genetics, 148 (3), 1215-24
DOI 10.1093/genetics/148.3.1215, PubMed 9539436
Publications 1996
Et morfologisk og kinetisk studie av store vesikulære strukturer i MDCK II-celler stabilt transfektert med Invariant chain
M.P. Oksvold, Oslo, 73 s.
BIBSYS 961645113