Translational Neurodegeneration Research & Neuropathology
Jens Pahnke Group leader
This combined research and diagnostic lab is located at Rikshospitalet. We provide daily diagnostic service for brain biopsy diagnostics, muscle disease diagnostics, routine autopsy diagnostics for adults, kids and fetuses, and forensic neuropathology consultations. Our research focuses on basic and molecular neurodegeneration research, translational projects, patient-related treatment and diagnostic research. We have several unique mouse lines located at the Radium Hospital mouse facility.
Santos-García I, Bascuñana P, Brackhan M, Villa M, Eiriz I, Brüning T, Pahnke J(2025) The ABC transporter A7 modulates neuroinflammation via NLRP3 inflammasome in Alzheimer's disease mice Alzheimers Res Ther, 17(1), 30 DOI 10.1186/s13195-025-01673-2, PubMed 39871385
Jotanovic J, Boldt HB, Burton M, Andersen MS, Bengtsson D, Bontell TO, Ekman B, Engström BE, Feldt-Rasmussen U, Heck A, Jakovcevic A, Jørgensen JOL, Kraljevic I, Kunicki J, Lindsay JR, Losa M, Loughrey PB, Maiter D, Maksymowicz M, Manojlovic-Gacic E, Pahnke J, Petersenn S, Petersson M, Popovic V, Ragnarsson Oet al.(2025) Correction: Genome‑wide methylation profiling differentiates benign from aggressive and metastatic pituitary neuroendocrine tumors Acta Neuropathol, 149(1), 4 DOI 10.1007/s00401-024-02838-3, PubMed 39747763
Wu J, Santos-Garcia I, Eiriz I, Brüning T, Kvasnička A, Friedecký D, Nyman TA, Pahnke J(2024) Sex-dependent efficacy of sphingosine-1-phosphate receptor agonist FTY720 in mitigating Huntington's disease Pharmacol Res, 211, 107557 DOI 10.1016/j.phrs.2024.107557, PubMed 39725338