Translational Neurodegeneration Research & Neuropathology
This combined research and diagnostic lab is located at Rikshospitalet. We provide daily diagnostic service for brain biopsy diagnostics, muscle disease diagnostics, routine autopsy diagnostics for adults, kids and fetuses, and forensic neuropathology consultations. Our research focuses on basic and molecular neurodegeneration research, translational projects, patient-related treatment and diagnostic research. We have several unique mouse lines located at the Radium Hospital mouse facility.
Stefan SM, Pahnke J, Namasivayam V(2023) HD_BPMDS: a curated binary pattern multitarget dataset of Huntington's disease-targeting agents J Cheminform, 15(1), 109 DOI 10.1186/s13321-023-00775-z, PubMed 37978560
Mairinger S, Leterrier S, Filip T, Löbsch M, Pahnke J, Hernández-Lozano I, Stanek J, Tournier N, Zeitlinger M, Hacker M, Langer O, Wanek T(2023) [11C]metoclopramide is a sensitive radiotracer to measure moderate decreases in P-glycoprotein function at the blood-brain barrier J Cereb Blood Flow Metab, 271678X231202336(in press) DOI 10.1177/0271678X231202336, PubMed 37728771
Möhle L, Stefan K, Bascuñana P, Brackhan M, Brüning T, Eiriz I, El Menuawy A, van Genderen S, Santos-García I, Górska AM, Villa M, Wu J, Stefan SM, Pahnke J(2023) ABC Transporter C1 Prevents Dimethyl Fumarate from Targeting Alzheimer's Disease Biology (Basel), 12(7) DOI 10.3390/biology12070932, PubMed 37508364