EurocanPlatform workshop May 18-19th Circulating Biomarkers in Cancer

The EurocanPlatform workshop on circulating biomarkers in cancer will take place at the Institute for Cancer Research, OUS, The Norwegian Radium Hospital from Monday May 18th to Tuesday May 19th. Deadline for abstract submissions: April 17th.

Professor Anne-Lise Borresen-Dale, head Dept of Genetics and the K.G. Jebsen Center for Breast Cancer Research, is co-ordinating the participation of OUS in the Eurocan Platform. She is also a member of the Project Steering Committee (PSC). Group leader Åslaug Helland is deputy in the Oslo part of the project, and leads the lung cancer focused projects.

EurocanPlatform is an EC funded project bringing together 28 European cancer Institutions and organisations to work together in a unique collaboration. The centres are sharing infrastructures and collaborating on projects to help advance cancer research and treatment. The platform of interlinked cancer centres with shared infrastructures and collaborative projects aim at facilitating rapid advances in knowledge, and their translation into better cancer care. There is a strong focus on discovery-driven translational cancer research.

Oslo University Hospital HF (OUS) is a partner in the project, and has been involved in several work packages. Anne-Lise Børresen-Dale, together with Maria Grazia Daidone (previously Marci Pierotti), leads WP3: Early detection and biomarker discovery. This work package has 16 involved partners, and very successful collaborations have been established, and with novel findings to be published. In addition, OUS is involved in work packages on therapeutic strategy, the technology, biobanking and epidemiology.

EurocanPlatform Workshop on Circulating Biomarkers in Cancer

Monday May 18, 2015:

10.00 Opening remarks: Anne-Lise Børresen-Dale

Key note lectures ( 35 minutes plus 10 min discussion)

The clinical need, James Brenton, UK Cambridge University
Circulating microRNAs , George Calin, MDAnderson, Texas
Single cell analyses, Bernhard Polzer, Fraunhofer ITEM-R, Regensburg, Germany

Lunch 13-14

CTCs, ctDNA, serum glycans: (presentations of 20' + 10' for discussion)

CTCs (enrichment/identification/enumeration/molecular characterizations, clinical value) Ged Brady, Manchester University
CTC's (Isolating CTCs for genomic profiling), Vera Cappelletti, Istituto Nazionale Tumori, Milan
ctDNA in blood, Hege Russnes, Oslo University Hospital

Coffee 15.30-16

ctDNA in CSF, characterization in brain tumors, Joan Seoane , Vall d'Hebron, Barcelona
serum glycans, Vilde Haakensen, Oslo University Hospital

17.00 Short presentations, selected from abstracts

18.00 poster presentations

19-22 Joint dinner (tapas)

Tuesday May 19: start 9.00

exosomes, miRNA, methylation, Glycans (presentations of 20' + 10' for discussion)

miRNA in blood for breast cancer diagnosis, Barbra Burwinkel, German Cancer Research Center (DKFZ)
Circulating miRNA for lung cancer diagnosis, Åslaug Helland, Oslo University Hospital
Exosomes and microvesicles, Veronica Huber, Istituto Nazionale Tumori, Milan
Methylation in blood, Zdenko Herceg, IARC

coffee 11-11.30

Clinical applications (presentations of 20' + 10' for discussion)

Monitoring disease progression, Bjørn Naume, Oslo University Hospital
Predicting treatment response, Francoise-Clément Bidard, Institute Curie, Paris

Lunch 12.30-13.30

Moving towards the future,

Moderator, Gordon McVie, European Institute of Oncology, Milan

Panel discussion, all speakers