
Gunnar B. Kristensen
- Senior consultant; MD, PhD
- +47 22 93 56 90
- Born in Denmark 1946.
- Medical Degree in 1972 from University of Århus, Denmark.
- Passed the American ECFMG examination in 1972.
- Received basic clinical training in Denmark followed by specialization in gynecology and obstetrics. Received board certification in gynecology and obstetrics in 1982.
- I Worked at the University Hospital of Odense in Denmark from 1982 to 1989 with special interest in surgical gynecologic oncology.
- In 1989 I decided to work full time with gynecologic oncology and took a job at the Norwegian Radium Hospital where I have worked since as consultant.
Early in my carrier I was interested in genital infections and carried out several studies on this topic. Also I was interested in the development of precancer and cancer of the squamous epithelium of the female genital tract. This interest led to a more general interest for gynecological cancer.
I have had a steady scientific production of articles related to squamous cell neoplasia. I have published about diagnostic and treatment related aspects of cervical preinvasive and invasive neoplasia and a great number of articles related to HPV and cervical neoplasia.
In recent years I have been working on studies on how to improve the efficacy of treatment for cervical cancer and at the same time reduce the morbidity from the treatment. These efforts have to a great extent been successful as evidenced by the increasing survival figures from our institution. As an example, I have introduced fertility saving surgery for early cervical cancer in Norway. Presently, we are running several studies to improve the detection of tumor spread outside the cervix at time of diagnosis, to predict prognosis and to predict the risk of late radiation damage after radiation for cervical cancer. In theses studies we are using themost modern techniques, such as PET scanning, dynamic MRI scanning and up-to-datelaboratory techniques with microarray technique, CGH and relevant protein analysis techniques.
I have been supervisor for several PhD students doing thesis work on both cervical cancer and ovarian cancer. The work on ovarian cancer has partly been clinical research and partly laboratory based biologic studies.
Since 1998 I have been president of the Nordic Society for Gynecologic Oncology, which is acooperative group engaged in clinical research. The society partly runs protocols of its own and partly international protocols developed by other groups. In this period, the organization has developed into a professional, internationally recognized Clinical Trials Organization.
I am author of 145 scientific articles in peer-reviewed journals and of 19 chapters in books.
I am principal investigator in GOG ( the American Gynecologic Oncology Group) for the Nordic countries.
I am reviewer for the following scientific journals:
Lancet, Gynecologic Oncology, Acta Obstet Gynecol Scand, Cancer Letters, International Journal Gynecological Cancer, Critical Review in Oncology, Exper Review Anticancer, Molecular Diagnostics
I am member of the following scientific organizations:
Nordic Society of Gynecologic Oncology, International Gynecological Cancer Society, American Society for Clinical Oncology (ASCO), European Society of Medical Oncology (ESMO), European Organization for Research and Treatment of Cancer-Gynecological Cancer Cooperative Group, Scandinavisk Selskap for Gynekologi og Obstetrik, Norsk Forum for Gynekologisk Onkologi,
Publications 2022
miR-200a/b/-429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer
Mol Oncol, 16 (6), 1402-1419
DOI 10.1002/1878-0261.13184, PubMed 35064630
Publications 2021
Randomized Trial of Cytoreductive Surgery for Relapsed Ovarian Cancer
N Engl J Med, 385 (23), 2123-2131
DOI 10.1056/NEJMoa2103294, PubMed 34874631
Risk Stratification of Endometrial Cancer Patients: FIGO Stage, Biomarkers and Molecular Classification
Cancers (Basel), 13 (22)
DOI 10.3390/cancers13225848, PubMed 34831000
Salvage Radiation for Pelvic Relapse after Surgically Treated Endometrial Cancer
Cancers (Basel), 13 (6)
DOI 10.3390/cancers13061367, PubMed 33803531
Long-term oncological outcomes and recurrence patterns in early-stage cervical cancer treated with minimally invasive versus abdominal radical hysterectomy: The Norwegian Radium Hospital experience
Gynecol Oncol, 162 (2), 284-291
DOI 10.1016/j.ygyno.2021.05.028, PubMed 34083029
Publications 2020
Combining imaging- and gene-based hypoxia biomarkers in cervical cancer improves prediction of chemoradiotherapy failure independent of intratumour heterogeneity
EBioMedicine, 57, 102841
DOI 10.1016/j.ebiom.2020.102841, PubMed 32580139
MRI Distinguishes Tumor Hypoxia Levels of Different Prognostic and Biological Significance in Cervical Cancer
Cancer Res, 80 (18), 3993-4003
DOI 10.1158/0008-5472.CAN-20-0950, PubMed 32606004
Prognostic Value of the Diversity of Nuclear Chromatin Compartments in Gynaecological Carcinomas
Cancers (Basel), 12 (12)
DOI 10.3390/cancers12123838, PubMed 33352679
DCE-MRI of locally-advanced carcinoma of the uterine cervix: Tofts analysis versus non-model-based analyses
Radiat Oncol, 15 (1), 79
DOI 10.1186/s13014-020-01526-2, PubMed 32293487
MILO/ENGOT-ov11: Binimetinib Versus Physician's Choice Chemotherapy in Recurrent or Persistent Low-Grade Serous Carcinomas of the Ovary, Fallopian Tube, or Primary Peritoneum
J Clin Oncol, 38 (32), 3753-3762
DOI 10.1200/JCO.20.01164, PubMed 32822286
Exploring international differences in ovarian cancer treatment: a comparison of clinical practice guidelines and patterns of care
Int J Gynecol Cancer, 30 (11), 1748-1756
DOI 10.1136/ijgc-2020-001403, PubMed 32784203
Assessment of Progression-Free Survival as a Surrogate End Point of Overall Survival in First-Line Treatment of Ovarian Cancer: A Systematic Review and Meta-analysis
JAMA Netw Open, 3 (1), e1918939
DOI 10.1001/jamanetworkopen.2019.18939, PubMed 31922558
Publications 2019
Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes
Clin Cancer Res, 25 (7), 2155-2165
DOI 10.1158/1078-0432.CCR-18-2792, PubMed 30617134
Mitochondrial Function of CKS2 Oncoprotein Links Oxidative Phosphorylation with Cell Division in Chemoradioresistant Cervical Cancer
Neoplasia, 21 (4), 353-362
DOI 10.1016/j.neo.2019.01.002, PubMed 30856376
Pharmacokinetic analysis of DCE-MRI data of locally advanced cervical carcinoma with the Brix model
Acta Oncol, 58 (6), 828-837
DOI 10.1080/0284186X.2019.1580386, PubMed 30810443
Reference MicroRNAs for RT-qPCR Assays in Cervical Cancer Patients and Their Application to Studies of HPV16 and Hypoxia Biomarkers
Transl Oncol, 12 (3), 576-584
DOI 10.1016/j.tranon.2018.12.010, PubMed 30660934
Neoadjuvant Chemotherapy Versus Debulking Surgery in Advanced Tubo-Ovarian Cancers: Pooled Analysis of Individual Patient Data From the EORTC 55971 and CHORUS Trials
Obstet. Gynecol. Surv., 74 (3), 156-158
DOI 10.1097/01.ogx.0000554460.78765.59
Publications 2018
Exploratory outcome analyses according to stage and/or residual disease in the ICON7 trial of carboplatin and paclitaxel with or without bevacizumab for newly diagnosed ovarian cancer
Gynecol Oncol, 152 (1), 53-60
DOI 10.1016/j.ygyno.2018.08.036, PubMed 30449719
Chromatin organisation and cancer prognosis: a pan-cancer study
Lancet Oncol, 19 (3), 356-369
DOI 10.1016/S1470-2045(17)30899-9, PubMed 29402700
Association Between Proportion of Nuclei With High Chromatin Entropy and Prognosis in Gynecological Cancers
J Natl Cancer Inst, 110 (12), 1400-1408
DOI 10.1093/jnci/djy063, PubMed 29684152
DCE-MRI-Derived Measures of Tumor Hypoxia and Interstitial Fluid Pressure Predict Outcomes in Cervical Carcinoma
Int J Radiat Oncol Biol Phys, 102 (4), 1193-1201
DOI 10.1016/j.ijrobp.2018.04.035, PubMed 29859790
Clinical Outcome of Patients With High-Risk Endometrial Carcinoma After Treatment With Chemotherapy Only
Int J Gynecol Cancer, 28 (9), 1789-1795
DOI 10.1097/IGC.0000000000001356, PubMed 30365455
Neoadjuvant chemotherapy versus debulking surgery in advanced tubo-ovarian cancers: pooled analysis of individual patient data from the EORTC 55971 and CHORUS trials
Lancet Oncol, 19 (12), 1680-1687
DOI 10.1016/S1470-2045(18)30566-7, PubMed 30413383
Publications 2017
Evaluation of Prognostic and Predictive Significance of Circulating MicroRNAs in Ovarian Cancer Patients
Dis Markers, 2017, 3098542
DOI 10.1155/2017/3098542, PubMed 28293063
[Properties of cancer cell DNA affects the prognosis]
Tidsskr Nor Laegeforen, 137 (19)
DOI 10.4045/tidsskr.16.0966, PubMed 29043733
Characteristics of tumor cell DNA affect prognosis
Tidsskr. Nor. Laegeforen., 137 (19), 1519-1523
Chemotherapy vs tamoxifen in platinum-resistant ovarian cancer: a phase III, randomised, multicentre trial (Ovaresist)
Br J Cancer, 116 (4), 455-463
DOI 10.1038/bjc.2016.435, PubMed 28118323
Pretreatment late-phase DCE-MRI predicts outcome in locally advanced cervix cancer
Acta Oncol, 56 (5), 675-681
DOI 10.1080/0284186X.2017.1294762, PubMed 28447564
Vulvar carcinoma in Norway: A 50-year perspective on trends in incidence, treatment and survival
Gynecol Oncol, 145 (3), 543-548
DOI 10.1016/j.ygyno.2017.03.008, PubMed 28356187
Rare ovarian tumours: Epidemiology, treatment challenges in and outside a network setting
Eur J Surg Oncol, 45 (1), 67-74
DOI 10.1016/j.ejso.2017.09.025, PubMed 29108961
A national, prospective observational study of first recurrence after primary treatment for gynecological cancer in Norway
Acta Obstet Gynecol Scand, 96 (10), 1162-1169
DOI 10.1111/aogs.13199, PubMed 28795770
Publications 2016
Progesterone Receptor Expression Is an Independent Prognosticator in FIGO Stage I Uterine Leiomyosarcoma
Am J Clin Pathol, 145 (4), 449-58
DOI 10.1093/ajcp/aqw030, PubMed 27149024
Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer
Clin Cancer Res, 22 (16), 4067-76
DOI 10.1158/1078-0432.CCR-15-2322, PubMed 27012812
Identification and Validation of Reference Genes for RT-qPCR Studies of Hypoxia in Squamous Cervical Cancer Patients
PLoS One, 11 (5), e0156259
DOI 10.1371/journal.pone.0156259, PubMed 27244197
Operability and chemotherapy responsiveness in advanced low-grade serous ovarian cancer. An analysis of the AGO Study Group metadatabase
Gynecol Oncol, 140 (3), 457-62
DOI 10.1016/j.ygyno.2016.01.022, PubMed 26807488
Poor concordance between CA-125 and RECIST at the time of disease progression in patients with platinum-resistant ovarian cancer: analysis of the AURELIA trial
Ann Oncol, 27 (8), 1505-10
DOI 10.1093/annonc/mdw238, PubMed 27407100
Efficacy and safety of fosaprepitant for the prevention of nausea and emesis during 5 weeks of chemoradiotherapy for cervical cancer (the GAND-emesis study): a multinational, randomised, placebo-controlled, double-blind, phase 3 trial
Lancet Oncol, 17 (4), 509-518
DOI 10.1016/S1470-2045(15)00615-4, PubMed 26952945
L1CAM as a prognostic marker in stage I endometrial cancer: a validation study
BMC Cancer, 16, 596
DOI 10.1186/s12885-016-2631-4, PubMed 27488577
Safety and efficacy of single-agent bevacizumab-containing therapy in elderly patients with platinum-resistant recurrent ovarian cancer: Subgroup analysis of the randomised phase III AURELIA trial
Gynecol Oncol, 144 (1), 65-71
DOI 10.1016/j.ygyno.2016.11.006, PubMed 27871723
Prognostic and predictive effects of primary versus secondary platinum resistance for bevacizumab treatment for platinum-resistant ovarian cancer in the AURELIA trial
Ann Oncol, 27 (9), 1733-9
DOI 10.1093/annonc/mdw236, PubMed 27287207
Systematic analysis of circulating soluble angiogenesis-associated proteins in ICON7 identifies Tie2 as a biomarker of vascular progression on bevacizumab
Br J Cancer, 115 (2), 228-35
DOI 10.1038/bjc.2016.194, PubMed 27351218
Publications 2015
Standard first-line chemotherapy with or without nintedanib for advanced ovarian cancer (AGO-OVAR 12): a randomised, double-blind, placebo-controlled phase 3 trial
Lancet Oncol, 17 (1), 78-89
DOI 10.1016/S1470-2045(15)00366-6, PubMed 26590673
Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer
Epigenetics, 10 (10), 970-80
DOI 10.1080/15592294.2015.1085140, PubMed 26291246
Short-term pretreatment DCE-MRI in prediction of outcome in locally advanced cervical cancer
Radiother Oncol, 115 (3), 379-85
DOI 10.1016/j.radonc.2015.05.001, PubMed 25998804
Standard chemotherapy with or without bevacizumab for women with newly diagnosed ovarian cancer (ICON7): overall survival results of a phase 3 randomised trial
Lancet Oncol, 16 (8), 928-36
DOI 10.1016/S1470-2045(15)00086-8, PubMed 26115797
Multinational study exploring patients' perceptions of side-effects induced by chemo-radiotherapy
Radiother Oncol, 117 (2), 333-7
DOI 10.1016/j.radonc.2015.09.014, PubMed 26372344
Alopecia as surrogate marker for chemotherapy response in patients with primary epithelial ovarian cancer: a metaanalysis of four prospective randomised phase III trials with 5114 patients
Eur J Cancer, 51 (7), 825-32
DOI 10.1016/j.ejca.2015.01.008, PubMed 25771433
Publications 2014
Gynecologic Cancer InterGroup (GCIG) consensus review for endometrial stromal sarcoma
Int J Gynecol Cancer, 24 (9 Suppl 3), S67-72
DOI 10.1097/IGC.0000000000000205, PubMed 25033257
Gynecologic Cancer InterGroup (GCIG) consensus review for mullerian adenosarcoma of the female genital tract
Int J Gynecol Cancer, 24 (9 Suppl 3), S78-82
DOI 10.1097/IGC.0000000000000239, PubMed 25341585
Peritumoral interstitial fluid flow velocity predicts survival in cervical carcinoma
Radiother Oncol, 113 (1), 132-8
DOI 10.1016/j.radonc.2014.09.011, PubMed 25443501
Examestane in advanced or recurrent endometrial carcinoma: a prospective phase II study by the Nordic Society of Gynecologic Oncology (NSGO)
BMC Cancer, 14, 68
DOI 10.1186/1471-2407-14-68, PubMed 24498853
Entropy-based adaptive nuclear texture features are independent prognostic markers in a total population of uterine sarcomas
Cytometry A, 87 (4), 315-25
DOI 10.1002/cyto.a.22601, PubMed 25483227
Bevacizumab combined with chemotherapy for platinum-resistant recurrent ovarian cancer: The AURELIA open-label randomized phase III trial
J Clin Oncol, 32 (13), 1302-8
DOI 10.1200/JCO.2013.51.4489, PubMed 24637997
Gynecologic Cancer InterGroup (GCIG) consensus review for uterine serous carcinoma
Int J Gynecol Cancer, 24 (9 Suppl 3), S83-9
DOI 10.1097/IGC.0000000000000264, PubMed 25341586
A multicenter, non-randomized, phase II study of docetaxel and carboplatin administered every 3 weeks as second line chemotherapy in patients with first relapse of platinum sensitive epithelial ovarian, peritoneal or fallopian tube cancer
BMC Cancer, 14, 937
DOI 10.1186/1471-2407-14-937, PubMed 25494701
Publications 2013
Pharmacokinetic parameters derived from dynamic contrast enhanced MRI of cervical cancers predict chemoradiotherapy outcome
Radiother Oncol, 107 (1), 117-22
DOI 10.1016/j.radonc.2012.11.007, PubMed 23333024
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
DOI 10.1371/journal.pone.0054356, PubMed 23372714
Gene expression signatures of primary and metastatic uterine leiomyosarcoma
Hum Pathol, 45 (4), 691-700
DOI 10.1016/j.humpath.2013.11.003, PubMed 24485798
Quality of life of advanced ovarian cancer patients in the randomized phase III study comparing primary debulking surgery versus neo-adjuvant chemotherapy
Gynecol Oncol, 131 (2), 437-44
DOI 10.1016/j.ygyno.2013.08.014, PubMed 23994107
Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling
J Pathol, 230 (1), 59-69
DOI 10.1002/path.4168, PubMed 23335387
Long-term outcomes after pelvic radiation for early-stage endometrial cancer
J Clin Oncol, 31 (31), 3951-6
DOI 10.1200/JCO.2013.48.8023, PubMed 24019546
Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovarian Neoplasms (ICON7) phase 3 randomised trial
Lancet Oncol, 14 (3), 236-43
DOI 10.1016/S1470-2045(12)70567-3, PubMed 23333117
Publications 2012
Hypoxia-induced gene expression in chemoradioresistant cervical cancer revealed by dynamic contrast-enhanced MRI
Cancer Res, 72 (20), 5285-95
DOI 10.1158/0008-5472.CAN-12-1085, PubMed 22890239
Phase I study of saracatinib (AZD0530) in combination with paclitaxel and/or carboplatin in patients with solid tumours
Br J Cancer, 106 (11), 1728-34
DOI 10.1038/bjc.2012.158, PubMed 22531637
A prognostic nomogram to predict overall survival in patients with platinum-sensitive recurrent ovarian cancer
Ann Oncol, 24 (4), 937-43
DOI 10.1093/annonc/mds538, PubMed 23104722
First-line treatment of advanced ovarian cancer with paclitaxel/carboplatin with or without epirubicin (TEC versus TC)--a gynecologic cancer intergroup study of the NSGO, EORTC GCG and NCIC CTG
Ann Oncol, 23 (10), 2613-2619
DOI 10.1093/annonc/mds060, PubMed 22539562
The prognostic value of adaptive nuclear texture features from patient gray level entropy matrices in early stage ovarian cancer
Anal Cell Pathol (Amst), 35 (4), 305-14
DOI 10.3233/ACP-2012-0065, PubMed 22596183
DNA ploidy may be a prognostic marker in stage I and II serous adenocarcinoma of the endometrium
Virchows Arch, 461 (3), 291-8
DOI 10.1007/s00428-012-1275-2, PubMed 22824999
Diagnosis and treatment of sarcoma of the uterus. A review
Acta Oncol, 51 (6), 694-705
DOI 10.3109/0284186X.2012.689111, PubMed 22793037
Publications 2011
Dynamic contrast-enhanced MRI of cervical cancers: temporal percentile screening of contrast enhancement identifies parameters for prediction of chemoradioresistance
Int J Radiat Oncol Biol Phys, 82 (3), e485-92
DOI 10.1016/j.ijrobp.2011.05.050, PubMed 22014954
Pharmacokinetic analysis and k-means clustering of DCEMR images for radiotherapy outcome prediction of advanced cervical cancers
Acta Oncol, 50 (6), 859-65
DOI 10.3109/0284186X.2011.578586, PubMed 21767185
Phosphorylation of EGFR measured with in situ proximity ligation assay: relationship to EGFR protein level and gene dosage in cervical cancer
Radiother Oncol, 101 (1), 152-7
DOI 10.1016/j.radonc.2011.05.052, PubMed 21680035
Membranous expression of ectodomain isoforms of the epidermal growth factor receptor predicts outcome after chemoradiotherapy of lymph node-negative cervical cancer
Clin Cancer Res, 17 (16), 5501-12
DOI 10.1158/1078-0432.CCR-11-0297, PubMed 21737508
Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers
PLoS One, 6 (4), e18064
DOI 10.1371/journal.pone.0018064, PubMed 21533284
Genomic imbalances in endometrial adenocarcinomas - comparison of DNA ploidy, karyotyping and comparative genomic hybridization
Mol Oncol, 6 (1), 98-107
DOI 10.1016/j.molonc.2011.10.002, PubMed 22062770
A phase 3 trial of bevacizumab in ovarian cancer
N Engl J Med, 365 (26), 2484-96
DOI 10.1056/NEJMoa1103799, PubMed 22204725
Prognostic importance of DNA ploidy and DNA index in stage I and II endometrioid adenocarcinoma of the endometrium
Ann Oncol, 23 (5), 1178-1184
DOI 10.1093/annonc/mdr368, PubMed 21965471
Definitions for response and progression in ovarian cancer clinical trials incorporating RECIST 1.1 and CA 125 agreed by the Gynecological Cancer Intergroup (GCIG)
Int J Gynecol Cancer, 21 (2), 419-23
DOI 10.1097/IGC.0b013e3182070f17, PubMed 21270624
First-line therapy in ovarian cancer trials
Int J Gynecol Cancer, 21 (4), 756-62
DOI 10.1097/IGC.0b013e31821ce75d, PubMed 21543937
Primary surgery or neoadjuvant chemotherapy followed by interval debulking surgery in advanced ovarian cancer
Eur J Cancer, 47 Suppl 3, S88-92
DOI 10.1016/S0959-8049(11)70152-6, PubMed 21944035
A study of chronic pelvic pain after radiotherapy in survivors of locally advanced cervical cancer
J Cancer Surviv, 5 (2), 208-16
DOI 10.1007/s11764-011-0172-z, PubMed 21259075
Publications 2010
Phase III trial of carboplatin plus paclitaxel with or without gemcitabine in first-line treatment of epithelial ovarian cancer
J Clin Oncol, 28 (27), 4162-9
DOI 10.1200/JCO.2009.27.4696, PubMed 20733132
Sequential adjuvant chemotherapy and radiotherapy in endometrial cancer--results from two randomised studies
Eur J Cancer, 46 (13), 2422-31
DOI 10.1016/j.ejca.2010.06.002, PubMed 20619634
Pegylated liposomal Doxorubicin and Carboplatin compared with Paclitaxel and Carboplatin for patients with platinum-sensitive ovarian cancer in late relapse
J Clin Oncol, 28 (20), 3323-9
DOI 10.1200/JCO.2009.25.7519, PubMed 20498395
Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial
Lancet, 376 (9747), 1155-63
DOI 10.1016/S0140-6736(10)61268-8, PubMed 20888993
Surgery in treatment of recurrent cervical cancer
CME Journal of Gynecologic Oncology, 15 (1), 33-39
PublikaID 104
The treatment of recurrent cervical cancer
CME Journal of Gynecologic Oncology, 15 (1), 72-90
PublikaID 106
European Network of Gynaecological Oncological Trial Groups' requirements for trials between academic groups and pharmaceutical companies
Int J Gynecol Cancer, 20 (3), 476-8
DOI 10.1111/IGC.0b013e3181d3caa8, PubMed 20375816
Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer
N Engl J Med, 363 (10), 943-53
DOI 10.1056/NEJMoa0908806, PubMed 20818904
Quality of pathology reports for advanced ovarian cancer: are we missing essential information? An audit of 479 pathology reports from the EORTC-GCG 55971/NCIC-CTG OV13 neoadjuvant trial
Eur J Cancer, 47 (1), 57-64
DOI 10.1016/j.ejca.2010.08.008, PubMed 20850296
Publications 2009
Uterine sarcomas in Norway. A histopathological and prognostic survey of a total population from 1970 to 2000 including 419 patients
Histopathology, 54 (3), 355-64
DOI 10.1111/j.1365-2559.2009.03231.x, PubMed 19236512
Late effects after radiotherapy for locally advanced cervical cancer: comparison of two brachytherapy schedules and effect of dose delivered weekly
Int J Radiat Oncol Biol Phys, 76 (3), 713-8
DOI 10.1016/j.ijrobp.2009.02.024, PubMed 19427739
Expression of 14-3-3sigma in cervical squamous cell carcinomas: relationship with clinical outcome
Oncol Rep, 22 (1), 11-5
DOI 10.3892/or_00000399, PubMed 19513498
The prognostic value of DNA ploidy in a total population of uterine sarcomas
Ann Oncol, 20 (6), 1037-41
DOI 10.1093/annonc/mdn765, PubMed 19201782
Beta-catenin expression in uterine sarcomas and its relation to clinicopathological parameters
Eur J Cancer, 45 (13), 2412-7
DOI 10.1016/j.ejca.2009.06.017, PubMed 19622417
Gene dosage, expression, and ontology analysis identifies driver genes in the carcinogenesis and chemoradioresistance of cervical cancer
PLoS Genet, 5 (11), e1000719
DOI 10.1371/journal.pgen.1000719, PubMed 19911042
Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis
PLoS One, 4 (5), e5583
DOI 10.1371/journal.pone.0005583, PubMed 19440550
Hyperbaric oxygen therapy for late radiation tissue injury in gynaecological patients
Support Care Cancer, 17 (12), 1517-21
DOI 10.1007/s00520-009-0619-1, PubMed 19319575
Publications 2008
Expressions of EphA2 and EphrinA-1 in early squamous cell cervical carcinomas and their relation to prognosis
Int J Med Sci, 5 (3), 121-6
DOI 10.7150/ijms.5.121, PubMed 18566674
Human papillomavirus DNA and e6/e7 mRNA status in relation to survival of patients treated for cervical squamous cell carcinoma
Open Virol J, 2, 74-81
DOI 10.2174/1874357900802010074, PubMed 19440467
Human papillomavirus E6/E7 mRNA testing as a predictive marker for cervical carcinoma
Expert Rev Mol Diagn, 8 (4), 405-15
DOI 10.1586/14737159.8.4.405, PubMed 18598223
GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data
Genome Biol, 9 (5), R86
DOI 10.1186/gb-2008-9-5-r86, PubMed 18500990
Postradiotherapy morbidity in long-term survivors after locally advanced cervical cancer: how well do physicians' assessments agree with those of their patients?
Int J Radiat Oncol Biol Phys, 71 (5), 1335-42
DOI 10.1016/j.ijrobp.2007.12.030, PubMed 18355976
Intestinal malabsorption in long-term survivors of cervical cancer treated with radiotherapy
Int J Radiat Oncol Biol Phys, 73 (4), 1141-7
DOI 10.1016/j.ijrobp.2008.05.064, PubMed 18760883
Publications 2007
Metabolic mapping by use of high-resolution magic angle spinning 1H MR spectroscopy for assessment of apoptosis in cervical carcinomas
BMC Cancer, 7, 11
DOI 10.1186/1471-2407-7-11, PubMed 17233882
Clinical trials in gynecological cancer
Int J Gynecol Cancer, 17 (3), 547-56
DOI 10.1111/j.1525-1438.2007.00667.x, PubMed 17504371
Chronic fatigue and its correlates in long-term survivors of cervical cancer treated with radiotherapy
BJOG, 114 (9), 1150-8
DOI 10.1111/j.1471-0528.2007.01445.x, PubMed 17655733
The sexual activity questionnaire: pychometric properties and normative data in a norwegian population sample
J Womens Health (Larchmt), 16 (1), 139-48
DOI 10.1089/jwh.2006.0052, PubMed 17324105
TP53 mutations and codon 72 genotype--impact on survival among ovarian cancer patients
Ann Oncol, 18 (5), 964-6
DOI 10.1093/annonc/mdm134, PubMed 17488735
Publications 2006
High sensitivity assays for docetaxel and paclitaxel in plasma using solid-phase extraction and high-performance liquid chromatography with UV detection
BMC Clin Pharmacol, 6, 2
DOI 10.1186/1472-6904-6-2, PubMed 16412237
Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers
PLoS Med, 3 (3), e47
DOI 10.1371/journal.pmed.0030047, PubMed 16417408
Proteomic analysis of malignant ovarian cancer effusions as a tool for biologic and prognostic profiling
Clin Cancer Res, 12 (3 Pt 1), 791-9
DOI 10.1158/1078-0432.CCR-05-2516, PubMed 16467090
Presence of E6 and E7 mRNA from human papillomavirus types 16, 18, 31, 33, and 45 in the majority of cervical carcinomas
J Clin Microbiol, 44 (4), 1310-7
DOI 10.1128/JCM.44.4.1310-1317.2006, PubMed 16597856
Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer
BMC Genomics, 7, 268
DOI 10.1186/1471-2164-7-268, PubMed 17054779
The prognostic impact of EphB2/B4 expression on patients with advanced ovarian carcinoma
Gynecol Oncol, 102 (1), 15-21
DOI 10.1016/j.ygyno.2005.11.034, PubMed 16499955
Publications 2005
High-resolution gene copy number and expression profiling of human chromosome 22 in ovarian carcinomas
Genes Chromosomes Cancer, 42 (3), 228-37
DOI 10.1002/gcc.20128, PubMed 15578687
Apolipoprotein E is required for cell proliferation and survival in ovarian cancer
Cancer Res, 65 (1), 331-7
PubMed 15665311
2004 consensus statements on the management of ovarian cancer: final document of the 3rd International Gynecologic Cancer Intergroup Ovarian Cancer Consensus Conference (GCIG OCCC 2004)
Ann Oncol, 16 Suppl 8, viii7-viii12
DOI 10.1093/annonc/mdi961, PubMed 16239238
The clinical significance of EphA2 and Ephrin A-1 in epithelial ovarian carcinomas
Gynecol Oncol, 99 (2), 278-86
DOI 10.1016/j.ygyno.2005.06.036, PubMed 16061279
beta-catenin expression, DNA ploidy and clinicopathological features in ovarian cancer: a study in 253 patients
Eur J Cancer, 41 (8), 1127-34
DOI 10.1016/j.ejca.2005.01.022, PubMed 15911235
TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survival
BMC Cancer, 5, 134
DOI 10.1186/1471-2407-5-134, PubMed 16229746
Variation in gene expression patterns in effusions and primary tumors from serous ovarian cancer patients
Mol Cancer, 4, 26
DOI 10.1186/1476-4598-4-26, PubMed 16042759
Expression of xeroderma pigmentosum A protein predicts improved outcome in metastatic ovarian carcinoma
Cancer, 103 (11), 2313-9
DOI 10.1002/cncr.21031, PubMed 15844177
3rd International Ovarian Cancer Consensus Conference: outstanding issues for future consideration
Ann Oncol, 16 Suppl 8, viii36-viii38
DOI 10.1093/annonc/mdi965, PubMed 16239235
Clinical trials in ovarian carcinoma: requirements for standard approaches and regimens
Ann Oncol, 16 Suppl 8, viii13-viii19
DOI 10.1093/annonc/mdi962, PubMed 16239232
Markers of apoptosis in stage IB squamous cervical carcinoma
J Clin Pathol, 58 (6), 590-4
DOI 10.1136/jcp.2004.021220, PubMed 15917408
Risk grouping in stage IB squamous cell cervical carcinoma
Gynecol Oncol, 99 (1), 106-12
DOI 10.1016/j.ygyno.2005.05.026, PubMed 16137752
PIK3CA mutations in advanced ovarian carcinomas
Hum Mutat, 25 (3), 322
DOI 10.1002/humu.9316, PubMed 15712344
Protein expression and prognostic value of genes in the erb-b signaling pathway in advanced ovarian carcinomas
Am J Clin Pathol, 124 (3), 392-401
DOI 10.1309/BL7E-MW66-LQX6-GFRP, PubMed 16191507
Publications 2004
Granulin-epithelin precursor is a novel prognostic marker in epithelial ovarian carcinoma
Cancer, 100 (10), 2139-47
DOI 10.1002/cncr.20219, PubMed 15139056
The clinical role of the PEA3 transcription factor in ovarian and breast carcinoma in effusions
Clin Exp Metastasis, 21 (3), 191-9
DOI 10.1023/b:clin.0000037703.37275.35, PubMed 15387369
Endometrial cancer: the management of high-risk disease
Curr Oncol Rep, 6 (6), 471-5
DOI 10.1007/s11912-004-0078-2, PubMed 15485617
Intratumor chromosomal heterogeneity in advanced carcinomas of the uterine cervix
Int J Cancer, 111 (3), 358-66
DOI 10.1002/ijc.20258, PubMed 15221962
Genomic aberrations in carcinomas of the uterine corpus
Genes Chromosomes Cancer, 40 (3), 229-46
DOI 10.1002/gcc.20038, PubMed 15139002
E-cadherin and catenins in early squamous cervical carcinoma
Gynecol Oncol, 94 (2), 521-7
DOI 10.1016/j.ygyno.2004.05.046, PubMed 15297198
Cyclins and proliferation markers in early squamous cervical carcinoma
Gynecol Oncol, 92 (1), 40-6
DOI 10.1016/j.ygyno.2003.10.022, PubMed 14751136
TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival
Br J Cancer, 90 (3), 678-85
DOI 10.1038/sj.bjc.6601537, PubMed 14760384
Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma
Hum Mutat, 24 (1), 21-34
DOI 10.1002/humu.20055, PubMed 15221786
Prognostic significance of dysadherin expression in cervical squamous cell carcinoma
Pathol Oncol Res, 10 (4), 212-8
DOI 10.1007/BF03033763, PubMed 15619642
Prognostic value of EphA2 and EphrinA-1 in squamous cell cervical carcinoma
Gynecol Oncol, 94 (2), 312-9
DOI 10.1016/j.ygyno.2004.05.019, PubMed 15297167
Publications 2003
The prognostic impact of cyclin dependent kinase inhibitors p21WAF1, p27Kip1, and p16INK4/MTS1 in adenocarcinomas of the uterine cervix: an immunohistochemical evaluation of expression patterns in population-based material from 142 patients with international federation of gynecology and obstetrics stage I and II adenocarcinoma
Cancer, 98 (9), 1880-9
DOI 10.1002/cncr.11727, PubMed 14584070
ICON4/AGO-OVAR-2.2: questions about trial design, cost-effectiveness, and clinical benefit - Reply
Lancet, 362 (9392), 1334
DOI 10.1016/S0140-6736(03)14604-1
EMMPRIN (extracellular matrix metalloproteinase inducer) is a novel marker of poor outcome in serous ovarian carcinoma
Clin Exp Metastasis, 20 (2), 161-9
DOI 10.1023/a:1022696012668, PubMed 12705637
Expression of the 67 kDa laminin receptor and the alpha6 integrin subunit in serous ovarian carcinoma
Clin Exp Metastasis, 20 (7), 599-609
DOI 10.1023/a:1027340208536, PubMed 14669791
Genome profiles of bilateral dysgerminomas, a unilateral gonadoblastoma, and a metastasis from a 46, XY phenotypic female
Hum Pathol, 34 (9), 946-9
DOI 10.1016/s0046-8177(03)00345-9, PubMed 14562293
Large-scale genomic instability predicts long-term outcome for women with invasive stage I ovarian cancer
Ann Oncol, 14 (10), 1494-500
DOI 10.1093/annonc/mdg403, PubMed 14504048
First-line treatment of ovarian cancer FIGO stages IIb-IV with paclitaxel/epirubicin/carboplatin versus paclitaxel/carboplatin
Int J Gynecol Cancer, 13 Suppl 2, 172-7
DOI 10.1111/j.1525-1438.2003.13363.x, PubMed 14656276
X chromosome inactivation in cervical cancer patients
Cancer Genet Cytogenet, 146 (1), 73-6
DOI 10.1016/s0165-4608(03)00152-3, PubMed 14499700
Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial
Lancet, 361 (9375), 2099-106
DOI 10.1016/s0140-6736(03)13718-x, PubMed 12826431
Gene expression patterns in ovarian carcinomas
Mol Biol Cell, 14 (11), 4376-86
DOI 10.1091/mbc.e03-05-0279, PubMed 12960427
Expression of p27, p21, and p16 protein in early squamous cervical cancer and its relation to prognosis
Gynecol Oncol, 89 (1), 140-7
DOI 10.1016/s0090-8258(03)00010-6, PubMed 12694668
Publications 2002
Caveolin-1 expression in ovarian carcinoma is MDR1 independent
Am J Clin Pathol, 117 (2), 225-34
DOI 10.1309/u40r-1bn4-6kj3-bdg3, PubMed 11863219
Interleukin-8 and vascular endothelial growth factor mRNA and protein levels are down-regulated in ovarian carcinoma cells in serous effusions
Clin Exp Metastasis, 19 (2), 135-44
DOI 10.1023/a:1014582911680, PubMed 11964077
Publications 2001
Histologic subtype has minor importance for overall survival in patients with adenocarcinoma of the uterine cervix: a population-based study of prognostic factors in 505 patients with nonsquamous cell carcinomas of the cervix
Cancer, 92 (9), 2471-83
DOI 10.1002/1097-0142(20011101)92:9<2471::aid-cncr1597>3.0.co;2-k, PubMed 11745305
Phase I/II trial of the multidrug-resistance modulator valspodar combined with cisplatin and doxorubicin in refractory ovarian cancer
J Clin Oncol, 19 (12), 2983-93
DOI 10.1200/JCO.2001.19.12.2983, PubMed 11408493
Oral topotecan as single-agent second-line chemotherapy in patients with advanced ovarian cancer
J Clin Oncol, 19 (19), 3967-75
DOI 10.1200/JCO.2001.19.19.3967, PubMed 11579118
Fibroblast growth factor receptor 3 (FGFR3) - analyses of the S249C mutation and protein expression in primary cervical carcinomas
Anal Cell Pathol, 23 (2), 45-9
DOI 10.1155/2001/521873, PubMed 11904459
Expression of membrane-type 1, 2, and 3 matrix metalloproteinases messenger RNA in ovarian carcinoma cells in serous effusions
Am J Clin Pathol, 115 (4), 517-24
DOI 10.1309/B1YX-L8DB-TGY1-7905, PubMed 11293899
Expression levels of the nerve growth factor receptors TrkA and p75 in effusions and solid tumors of serous ovarian carcinoma patients
Clin Cancer Res, 7 (11), 3457-64
PubMed 11705863
Ovarian carcinoma cells in serous effusions show altered MMP-2 and TIMP-2 mRNA levels
Eur J Cancer, 37 (16), 2040-9
DOI 10.1016/s0959-8049(01)00235-0, PubMed 11597382
Expression of cell cycle proteins in ovarian carcinoma cells in serous effusions-biological and prognostic implications
Gynecol Oncol, 83 (2), 249-56
DOI 10.1006/gyno.2001.6388, PubMed 11606079
Ets-1 mRNA expression in effusions of serous ovarian carcinoma patients is a marker of poor outcome
Am J Surg Pathol, 25 (12), 1493-500
DOI 10.1097/00000478-200112000-00004, PubMed 11717538
Frequency of nightly wetting and the efficiency of alarm treatment of nocturnal enuresis
Scand J Urol Nephrol, 35 (5), 357-63
DOI 10.1080/003655901753224404, PubMed 11771861
Mineralization of aged atrazine and mecoprop in soil and aquifer chalk
Chemosphere, 45 (6-7), 927-34
DOI 10.1016/s0045-6535(01)00020-0, PubMed 11695615
Mineralization of 2,4-D, mecoprop, isoproturon and terbuthylazine in a chalk aquifer
Pest Manag Sci, 57 (6), 531-6
DOI 10.1002/ps.315, PubMed 11407030
Long-term results from a phase II study of paclitaxel combined with doxorubicin in recurrent platinum refractory ovarian cancer
Eur J Gynaecol Oncol, 22 (3), 223-7
PubMed 11501778
Clear-cell and papillary serous cancer: treatment options
Best Pract Res Clin Obstet Gynaecol, 15 (3), 433-46
DOI 10.1053/beog.2000.0187, PubMed 11476564
Publications 2000
Histopathologic subtyping of cervical adenocarcinoma reveals increasing incidence rates of endometrioid tumors in all age groups: a population based study with review of all nonsquamous cervical carcinomas in Norway from 1966 to 1970, 1976 to 1980, and 1986 to 1990
Cancer, 89 (6), 1291-9
DOI 10.1002/1097-0142(20000915)89:6<1291::AID-CNCR14>3.3.CO;2-F, PubMed 11002225
Expression of apoptosis-related proteins is an independent determinant of patient prognosis in advanced ovarian cancer
J Clin Oncol, 18 (22), 3775-81
DOI 10.1200/JCO.2000.18.22.3775, PubMed 11078490
Carcinoma of the fallopian tube
Cancer, 89 (10), 2076-84
PubMed 11066048
P-glycoprotein expression is a marker for chemotherapy resistance and prognosis in advanced ovarian cancer
Anticancer Res, 20 (2B), 1061-7
PubMed 10810398
Expression of CD44 in effusions of patients diagnosed with serous ovarian carcinoma--diagnostic and prognostic implications
Clin Exp Metastasis, 18 (2), 197-202
DOI 10.1023/a:1006711320107, PubMed 11235996
E-cadherin and alpha-, beta-, and gamma-catenin protein expression is up-regulated in ovarian carcinoma cells in serous effusions
J Pathol, 192 (4), 460-9
DOI 10.1002/1096-9896(2000)9999:9999<::AID-PATH726>3.0.CO;2-M, PubMed 11113863
Carbohydrate antigen expression in primary tumors, metastatic lesions, and serous effusions from patients diagnosed with epithelial ovarian carcinoma: evidence of up-regulated Tn and Sialyl Tn antigen expression in effusions
Hum Pathol, 31 (9), 1081-7
DOI 10.1053/hupa.2000.9776, PubMed 11014575
Primary cervical carcinomas show 2 common regions of deletion at 3P, 1 within the FHIT gene: evaluation of allelic imbalance at FHIT, RB1 and TP53 in relation to survival
Int J Cancer, 88 (2), 217-22
DOI 10.1002/1097-0215(20001015)88:2<217::aid-ijc11>3.0.co;2-i, PubMed 11004671
Effects of paclitaxel on CA-125 serum levels in ovarian cancer patients
Gynecol Oncol, 76 (3), 326-30
DOI 10.1006/gyno.1999.5699, PubMed 10684705
Randomized study on adjuvant chemotherapy in stage I high-risk ovarian cancer with evaluation of DNA-ploidy as prognostic instrument
Ann Oncol, 11 (3), 281-8
DOI 10.1023/a:1008399414923, PubMed 10811493
Surgery for borderline tumor of the ovary
Semin Surg Oncol, 19 (1), 69-75
DOI 10.1002/1098-2388(200007/08)19:1<69::aid-ssu11>3.0.co;2-e, PubMed 10883027
Re: new guidelines to evaluate the response to treatment in solid tumors [ovarian cancer]. Gynecologic Cancer Intergroup
J Natl Cancer Inst, 92 (18), 1534-5
DOI 10.1093/jnci/92.18.1534, PubMed 10995813
[Hyperbaric oxygen treatment for radiation reactions]
Tidsskr Nor Laegeforen, 120 (9), 1020-2
PubMed 10833959
Publications 1999
The arrow versus horizontal suture in arthroscopic meniscus repair. A prospective randomized study with arthroscopic evaluation
Knee Surg Sports Traumatol Arthrosc, 7 (5), 268-73
DOI 10.1007/s001670050162, PubMed 10525694
Lack of independent prognostic significance of p21 and p27 expression in advanced ovarian cancer: an immunohistochemical study
Clin Cancer Res, 5 (10), 2848-53
PubMed 10537352
The significance of metastasis-related factors cathepsin-D and nm23 in advanced ovarian cancer
Ann Oncol, 10 (11), 1335-41
DOI 10.1023/a:1008352502465, PubMed 10631462
Clinical significance of apoptosis-related factors p53, Mdm2, and Bcl-2 in advanced ovarian cancer
J Clin Oncol, 17 (7), 2061
DOI 10.1200/JCO.1999.17.7.2061, PubMed 10561259
Epidermal growth factor receptor expression has no independent prognostic significance in advanced ovarian cancer
Anticancer Res, 19 (5C), 4469-74
PubMed 10650794
Detection of cancer cells in effusions from patients diagnosed with gynaecological malignancies. Evaluation of five epithelial markers
Virchows Arch, 435 (1), 43-9
DOI 10.1007/s004280050393, PubMed 10431845
Prospectively detected cancer in familial breast/ovarian cancer screening
Acta Obstet Gynecol Scand, 78 (10), 906-11
DOI 10.1034/j.1600-0412.1999.781013.x, PubMed 10577622
Alarm treatment: analyses of response and relapse
Scand J Urol Nephrol Suppl, 202, 73-5
PubMed 10573801
Studies on prognostic factors in cervical cancer with special attention to early disease
Norwegian Radium Hospital, Oslo, 1 b. (flere pag.)
BIBSYS 991709624, ISBN 82-7722-111-8
Tumor size, depth of invasion, and grading of the invasive tumor front are the main prognostic factors in early squamous cell cervical carcinoma
Gynecol Oncol, 74 (2), 245-51
DOI 10.1006/gyno.1999.5420, PubMed 10419739
Allelic imbalance at chromosome region 11q23 in cervical carcinomas
Eur J Cancer, 35 (4), 659-63
DOI 10.1016/s0959-8049(98)00413-4, PubMed 10492643
Aberrant expression of the cell cycle associated proteins TP53, MDM2, p21, p27, cdk4, cyclin D1, RB, and EGFR in cervical carcinomas
Gynecol Oncol, 73 (2), 223-8
DOI 10.1006/gyno.1999.5346, PubMed 10329038
TP53 alterations in relation to the cell cycle-associated proteins p21, cyclin D1, CDK4, RB, MDM2, and EGFR in cancers of the uterine corpus
J Pathol, 187 (5), 556-62
DOI 10.1002/(SICI)1096-9896(199904)187:5<556::AID-PATH294>3.0.CO;2-Y, PubMed 10398121
Karyotypic findings in tumors of the vulva and vagina
Cancer Genet Cytogenet, 111 (1), 87-91
DOI 10.1016/s0165-4608(98)00226-x, PubMed 10326597
Publications 1998
The invasive front of carcinomas. The most important area for tumour prognosis?
Anticancer Res, 18 (6B), 4757-64
PubMed 9891553
Mutations in the TP53 gene and protein expression of p53, MDM 2 and p21/WAF-1 in primary cervical carcinomas with no or low human papillomavirus load
Br J Cancer, 78 (1), 69-72
DOI 10.1038/bjc.1998.444, PubMed 9662253
Randomized trial of recombinant human interleukin-3 versus placebo in prevention of bone marrow depression during first-line chemotherapy for ovarian carcinoma
J Clin Oncol, 16 (10), 3335-44
DOI 10.1200/JCO.1998.16.10.3335, PubMed 9779710
Disruption of the E1 and E2 reading frames of HPV 16 in cervical carcinoma is associated with poor prognosis
Int J Gynecol Pathol, 17 (2), 146-53
DOI 10.1097/00004347-199804000-00009, PubMed 9553812
Endoscopic resection of the septic prepatellar bursa
Arthroscopy, 14 (7), 757-8
DOI 10.1016/s0749-8063(98)70105-7, PubMed 9788374
Ten-year results of a randomised trial comparing cisplatin with cisplatin and cyclophosphamide in advanced, suboptimally debulked ovarian cancer
Eur J Cancer, 34 (8), 1175-80
DOI 10.1016/s0959-8049(97)10171-x, PubMed 9849475
Immunohistochemical analysis of p53 protein in uterine sarcomas
Gynecol Oncol, 70 (1), 45-8
DOI 10.1006/gyno.1998.5034, PubMed 9698472
A review of caveats in statistical nuclear image analysis
Anal Cell Pathol, 16 (2), 63-82
DOI 10.1155/1998/436382, PubMed 9692681
Controlled multicentre study of the influence of subcutaneous recombinant human erythropoietin on anaemia and transfusion dependency in patients with ovarian carcinoma treated with platinum-based chemotherapy
Med Oncol, 15 (3), 174-82
DOI 10.1007/BF02821936, PubMed 9819794
Publications 1997
Failure strength of a new meniscus arrow repair technique: biomechanical comparison with horizontal suture
Arthroscopy, 13 (2), 183-7
DOI 10.1016/s0749-8063(97)90153-5, PubMed 9127076
Microsatellite instability in cervical and endometrial carcinomas
Int J Cancer, 70 (5), 499-501
DOI 10.1002/(sici)1097-0215(19970304)70:5<499::aid-ijc1>3.0.co;2-t, PubMed 9052745
Epithelial ovarian carcinoma
Lancet, 349 (9045), 113-7
DOI 10.1016/S0140-6736(96)06071-0, PubMed 8996432
An evaluation of prognostic factors in uterine carcinosarcoma
Gynecol Oncol, 67 (3), 316-21
DOI 10.1006/gyno.1997.4875, PubMed 9441781
TP53 protein accumulation and gene mutation in relation to overexpression of MDM2 protein in ovarian borderline tumours and stage I carcinomas
J Pathol, 181 (2), 158-65
DOI 10.1002/(SICI)1096-9896(199702)181:2<158::AID-PATH742>3.0.CO;2-8, PubMed 9120719
Paclitaxel in untreated FIGO stage III suboptimally resected ovarian cancer
Ann Oncol, 8 (8), 803-6
DOI 10.1023/a:1008230909599, PubMed 9332691
Current status of chemotherapy in gynecologic cancer
Semin Oncol, 24 (5 Suppl 15), S15-1-S15-22
PubMed 9346216
Current status of chemotherapy in gynecologic cancer
Semin. Oncol., 24 (5 15), 1-22
Publications 1996
Early detection of familial ovarian cancer
Eur J Cancer, 32A (10), 1645-51
DOI 10.1016/0959-8049(96)00137-2, PubMed 8983269
Cisplatin/5-fluorouracil treatment of recurrent cervical carcinoma: a phase II study with long-term follow-up
Gynecol Oncol, 60 (3), 387-92
DOI 10.1006/gyno.1996.0059, PubMed 8774643
Use of multiple PCR primer sets for optimal detection of human papillomavirus
J Clin Microbiol, 34 (9), 2095-100
DOI 10.1128/jcm.34.9.2095-2100.1996, PubMed 8862564
Plasmodium falciparum: characterization of toxin-associated proteins and identification of a hemoglobin containing parasite cytokine stimulator
Exp Parasitol, 82 (2), 147-54
DOI 10.1006/expr.1996.0019, PubMed 8617341
Evaluation of the prognostic significance of nm23/NDP kinase protein expression in cervical carcinoma: an immunohistochemical study
Gynecol Oncol, 61 (3), 378-83
DOI 10.1006/gyno.1996.0160, PubMed 8641619
Evaluation of the prognostic significance of cathepsin D, epidermal growth factor receptor, and c-erbB-2 in early cervical squamous cell carcinoma. An immunohistochemical study
Cancer, 78 (3), 433-40
DOI 10.1002/(SICI)1097-0142(19960801)78:3<433::AID-CNCR9>3.0.CO;2-K, PubMed 8697388
Human papilloma virus has no prognostic significance in cervical carcinoma
Eur J Cancer, 32A (8), 1349-53
DOI 10.1016/0959-8049(96)00089-5, PubMed 8869098
The prognostic significance of surgery, tumor size, malignancy grade, menopausal status, and DNA ploidy in endometrial stromal sarcoma
Gynecol Oncol, 62 (2), 254-9
DOI 10.1006/gyno.1996.0224, PubMed 8751558
Malignant melanoma of the vulva FIGO stage I: Evaluation of prognostic factors in 43 patients with emphasis on DNA ploidy and surgical treatment
Gynecol Oncol, 61 (2), 253-8
DOI 10.1006/gyno.1996.0135, PubMed 8626143
Surgical treatment for cervical cancer and presentation of the genito urinary function
XXX WORLD CONGRESS OF THE INTERNATIONAL COLLEGE OF SURGEONS, VOLS 1-2, 1415-1424
Standard and new approaches in surgery
EUROPEAN SOCIETY FOR MEDICAL ONCOLOGY - 21ST ESMO CONGRESS, EDUCATIONAL BOOK, 51-56
Publications 1995
Implications of human papillomavirus type for survival in cervical squamous cell carcinoma
Int J Gynecol Cancer, 5 (5), 341-345
DOI 10.1046/j.1525-1438.1995.05050341.x, PubMed 11578501
High incidence of human papillomavirus in 146 cervical carcinomas. A study using three different pairs of consensus primers, and detecting viral genomes with putative deletions
Eur J Cancer, 31A (9), 1511-6
DOI 10.1016/0959-8049(95)00206-x, PubMed 7577081
A phase II study of carboplatin and hexamethylmelamine as induction chemotherapy in advanced epithelial ovarian carcinoma
Eur J Cancer, 31A (11), 1778-80
DOI 10.1016/0959-8049(95)00274-m, PubMed 8541099
No prognostic impact of flow-cytometric measured DNA ploidy and S-phase fraction in cancer of the uterine cervix: a prospective study of 465 patients
Gynecol Oncol, 57 (1), 79-85
DOI 10.1006/gyno.1995.1102, PubMed 7705705
The prognostic significance of residual disease, FIGO substage, tumor histology, and grade in patients with FIGO stage III ovarian cancer
Gynecol Oncol, 56 (2), 175-80
DOI 10.1006/gyno.1995.1027, PubMed 7896181
The prognostic significance of stage, tumor size, cellular atypia and DNA ploidy in uterine leiomyosarcoma
Acta Oncol, 34 (6), 797-802
DOI 10.3109/02841869509127189, PubMed 7576748
Malignant melanoma of the vulva. Evaluation of prognostic factors with emphasis on DNA ploidy in 75 patients
Cancer, 75 (1), 72-80
DOI 10.1002/1097-0142(19950101)75:1<72::aid-cncr2820750113>3.0.co;2-g, PubMed 7804980
TP53 gene mutations and protein accumulation in primary vaginal carcinomas
Br J Cancer, 72 (1), 129-33
DOI 10.1038/bjc.1995.288, PubMed 7599041
Expression of retinoblastoma tumor suppressor gene protein, epidermal growth factor receptor, and c-erbB-2 oncoprotein in primary vaginal carcinomas
Gynecol Oncol, 59 (3), 379-83
DOI 10.1006/gyno.1995.9958, PubMed 8522259
[Preoperative identification of malignancy among women with a pelvic mass]
Tidsskr Nor Laegeforen, 115 (7), 812-3
PubMed 7701484
Publications 1994
A randomised study of cisplatin versus thiotepa as induction chemotherapy in advanced ovarian carcinoma
Eur J Cancer, 30A (10), 1470-4
DOI 10.1016/0959-8049(94)00240-6, PubMed 7833104
DQA1 and DQB1 genes in patients with squamous cell carcinoma of the cervix: relationship to human papillomavirus infection and prognosis
Cancer Epidemiol Biomarkers Prev, 3 (6), 479-86
PubMed 8000298
Flow cytometric DNA ploidy and S-phase heterogeneity in advanced ovarian carcinoma
Cancer, 73 (7), 1870-7
DOI 10.1002/1097-0142(19940401)73:7<1870::aid-cncr2820730716>3.0.co;2-3, PubMed 8137213
Evaluation of deoxyribonucleic acid ploidy and S-phase fraction as prognostic parameters in advanced epithelial ovarian carcinoma: a prospective study
Am J Obstet Gynecol, 170 (2), 479-87
DOI 10.1016/s0002-9378(94)70215-2, PubMed 8116701
Human papillomavirus infection in Norwegian women with cervical cancer
APMIS, 102 (2), 122-8
DOI 10.1111/j.1699-0463.1994.tb04856.x, PubMed 8167008
The expression of c-erbB-2 (HER-2/neu) oncogene in invasive ovarian malignancies
Int J Gynecol Cancer, 4 (3), 194-199
DOI 10.1046/j.1525-1438.1994.04030194.x, PubMed 11578406
Publications 1993
Meniscus bucket-handle fixation with an absorbable Biofix tack: development of a new technique
Knee Surg Sports Traumatol Arthrosc, 1 (2), 104-6
DOI 10.1007/BF01565462, PubMed 8536003
Evaluation of endometrial thickness measured by endovaginal ultrasound in women with postmenopausal bleeding
Acta Obstet Gynecol Scand, 72 (2), 116-9
DOI 10.3109/00016349309023423, PubMed 8383406
Genetic alterations of the TP53 gene, p53 protein expression and HPV infection in primary cervical carcinomas
J Pathol, 171 (2), 105-14
DOI 10.1002/path.1711710207, PubMed 8283348
Immunohistochemical analysis of p53 protein overexpression in normal, premalignant, and malignant tissues of the cervix uteri
J Pathol, 169 (1), 21-6
DOI 10.1002/path.1711690105, PubMed 8433212
DNA ploidy; the most important prognostic factor in patients with borderline tumors of the ovary
Int J Gynecol Cancer, 3 (6), 349-358
DOI 10.1046/j.1525-1438.1993.03060349.x, PubMed 11578368
EVALUATION OF ENDOMETRIUM WITH TRANSVAGINAL ULTRASOUND - REPLY
Acta Obstet. Gynecol. Scand., 72 (8), 687
DOI 10.3109/00016349309021170
Evaluation of serum CA 125 level as a tumor marker in borderline tumors of the ovary
Int J Gynecol Cancer, 3 (5), 299-303
DOI 10.1046/j.1525-1438.1993.03050299.x, PubMed 11578361
Is serum CA 125 at the time of relapse a prognostic indicator for further survival prognosis in patients with ovarian cancer?
Gynecol Oncol, 49 (1), 3-7
DOI 10.1006/gyno.1993.1076, PubMed 8482556
Serum CA 125 level allows early identification of nonresponders during induction chemotherapy
Gynecol Oncol, 49 (1), 73-9
DOI 10.1006/gyno.1993.1089, PubMed 8482563
Serum CA 125 as a tumor marker and the expression of c-erbB-2 oncogene in tubal malignancies
Int J Gynecol Cancer, 3 (2), 116-121
DOI 10.1046/j.1525-1438.1993.03020116.x, PubMed 11578331
Antimicrobial resistance in human oral and intestinal anaerobic microfloras
Antimicrob Agents Chemother, 37 (8), 1665-9
DOI 10.1128/AAC.37.8.1665, PubMed 8215280
Are borderline tumors of the ovary overtreated both surgically and systemically? A review of four prospective randomized trials including 253 patients with borderline tumors
Gynecol Oncol, 51 (2), 236-43
DOI 10.1006/gyno.1993.1279, PubMed 8276300
Publications 1992
Subtrochanteric fractures following osteosynthesis of femoral neck fractures with the VLC-femoral system
Orthopedics, 15 (11), 1373-4
DOI 10.3928/0147-7447-19921101-19, PubMed 1461821
[Plant thorn synovitis]
Ugeskr Laeger, 154 (20), 1438
PubMed 1631975
CA 125 measured before second-look laparotomy is an independent prognostic factor for survival in patients with epithelial ovarian cancer
Gynecol Oncol, 45 (3), 323-8
DOI 10.1016/0090-8258(92)90313-8, PubMed 1612511
Prognostic value of pre- and postoperative serum CA 125 levels in ovarian cancer: new aspects and multivariate analysis
Obstet Gynecol, 79 (6), 1002-10
PubMed 1579296
Publications 1991
Analysis of cervical smears obtained within three years of the diagnosis of invasive cervical cancer
Acta Cytol, 35 (1), 47-50
PubMed 1994634
Publications 1990
[TV action 1989: NSF's relief project in Nepal started]
J Sykepleien, 78 (11), 18-20
PubMed 2123649
Fracture stage 4 of the lateral talar dome treated arthroscopically using Biofix for fixation
Arthroscopy, 6 (3), 242-4
DOI 10.1016/0749-8063(90)90082-o, PubMed 2169752
Single-dose cefuroxime prophylaxis in non-elective cesarean section
Acta Obstet Gynecol Scand, 69 (6), 497-500
DOI 10.3109/00016349009013325, PubMed 2126657
A randomized trial comparing two methods of cold knife conization with laser conization
Obstet Gynecol, 76 (6), 1009-13
PubMed 2234708
Publications 1989
Snapping knee from biceps femoris tendon. A case report
Acta Orthop Scand, 60 (5), 621
DOI 10.3109/17453678909150135, PubMed 2603666
Efficacy of the cytobrush versus the cotton swab in the collection of endocervical cells
Acta Cytol, 33 (6), 849-51
PubMed 2588918
The efficiency of the cytobrush and cotton swab in obtaining endocervical cells in smears taken after conization of the cervix
Arch Gynecol Obstet, 246 (4), 207-10
DOI 10.1007/BF00934520, PubMed 2619334
Publications 1988
Rupture of the knee capsule from articular hyperpressure. Experiments in cadaver knees
Acta Orthop Scand, 59 (6), 692-4
DOI 10.3109/17453678809149427, PubMed 3213458
Prognostic influence of ploidy level and histopathologic differentiation in cervical carcinoma stage Ib
Eur J Cancer Clin Oncol, 24 (6), 969-72
DOI 10.1016/0277-5379(88)90144-7, PubMed 3409946
Publications 1987
[Scavenging of excess gas from a pediatric nozzle insufflation system]
Ugeskr Laeger, 149 (14), 904-5
PubMed 3107184
[Hypothermia and the heart-lung machine]
Ugeskr Laeger, 149 (41), 2799
PubMed 3451528
Significance of antibodies to Mycoplasma genitalium in salpingitis
Eur J Clin Microbiol, 6 (2), 205-7
DOI 10.1007/BF02018216, PubMed 3297685
Publications 1986
[Offshore with the Norwegian Nurses' Association. Occupational health nurses on a visit to the continental shelf]
Sykepleien, 73 (4), 18-21, 35
PubMed 3633650
Simple system for central rewarming of hypothermic patients
Lancet, 2 (8521-22), 1467-8
DOI 10.1016/s0140-6736(86)92787-x, PubMed 2878324
Prevention of peroperative hypothermia in abdominal surgery
Acta Anaesthesiol Scand, 30 (4), 314-6
DOI 10.1111/j.1399-6576.1986.tb02421.x, PubMed 3739593
Publications 1985
An oesophageal thermal tube for rewarming in hypothermia
Acta Anaesthesiol Scand, 29 (8), 846-8
DOI 10.1111/j.1399-6576.1985.tb02308.x, PubMed 4082881
The outcome of pregnancy and preterm delivery after conization of the cervix
Arch Gynecol, 236 (3), 127-30
DOI 10.1007/BF02133954, PubMed 4015189
Infections with Neisseria gonorrhoeae and Chlamydia trachomatis in women with acute salpingitis
Genitourin Med, 61 (3), 179-84
DOI 10.1136/sti.61.3.179, PubMed 3924816
Importance of Mycoplasma hominis in acute salpingitis assessed by culture and serological tests
Genitourin Med, 61 (3), 185-9
DOI 10.1136/sti.61.3.185, PubMed 4007861
Publications 1984
[Evaluation of disposable and re-usable scalp electrodes]
Ugeskr Laeger, 146 (41), 3124-6
PubMed 6515949
Internal rewarming in hypothermia using a specially constructed gastro-oesophageal tube. A non-invasive method
Acta Anaesthesiol Belg, 35 Suppl, 175-7
PubMed 6516729
[Bran ileus. Mechanical ileus of the small intestine following ingestion of a bran diet, Amo-wheat bran]
Ugeskr Laeger, 146 (1), 29
PubMed 6320513
[Occupational accidents and drugs dangerous in traffic]
Ugeskr Laeger, 146 (32), 2432-3
PubMed 6515849
[Safety belts and fetal fractures of the cranium]
Ugeskr Laeger, 146 (46), 3553-4
PubMed 6515989
Androblastoma associated with pregnancy in two sisters. Case report
Br J Obstet Gynaecol, 91 (6), 592-5
DOI 10.1111/j.1471-0528.1984.tb04809.x, PubMed 6329260
Persistent bladder dysfunction after surgical and combination therapy of cancer of the cervix uteri stages Ib and IIa
Gynecol Oncol, 18 (1), 38-42
DOI 10.1016/0090-8258(84)90004-0, PubMed 6714805
[Prenatal evaluation of fetal lung maturity by measuring the optical density of amniotic fluid]
Ugeskr Laeger, 146 (47), 3635-7
PubMed 6515993
Publications 1983
[Transcutaneous bilirubinometry. A non-invasive method of measuring physiological jaundice]
Ugeskr Laeger, 145 (38), 2935-7
PubMed 6649103
[Traumatic rupture of the spleen treated by compression at exploratory laparotomy]
Ugeskr Laeger, 145 (19), 1453-4
PubMed 6879770
[Arrhenoblastomata in both ovaries with a 2-year interval]
Ugeskr Laeger, 145 (5), 331-2
PubMed 6302965
[Sexual dysfunction following operation for cancer of the uterine cervix stages Ib and IIa]
Ugeskr Laeger, 145 (3), 162-4
PubMed 6682582
Publications 1982
Demodex folliculorum hominis (Simon): incidence in a normomaterial and in patients under systemic treatment with erythromycin or glucocorticoid
Acta Derm Venereol, 62 (5), 454-6
PubMed 6183907
Publications 1981
[Cryocoagulation therapy of intra-epithelial cervical neoplasm]
Ugeskr Laeger, 143 (41), 2639-41
PubMed 7303286
[Insufflation of carbon dioxide. An alternative treatment in arterial insufficiency of the lower limbs]
Ugeskr Laeger, 143 (45), 2958-60
PubMed 6800086
Publications 1980
[Alcohol and occupational accidents. Records of an accident department in a provincial Danish town]
Ugeskr Laeger, 142 (47), 3147-8
PubMed 7445226
[2 cases of injuries caused by safety belts in pregnant women]
Ugeskr Laeger, 142 (17), 1092-3
PubMed 7385419
Publications 1978
Correlation between polyion effect on cell susceptibility to in vitro infection with murine C-type viruses and polyion effect on some membrane-related functions
Intervirology, 9 (3), 173-83
DOI 10.1159/000148934, PubMed 201587
Publications 1977
Correlation of in vivo cancer, net outer charge, in vitro migration, interferon activity, in vitro growth rates, and chalone-like activity to transformation-reversion in cloned Moloney and Kristen sarcoma virus-transformed mouse 3T3 cells
Cancer Res, 37 (12), 4285-90
PubMed 200345
Publications 1962
Effects of various dietary fats on serum cholesterol, liver lipids and tissue pathology in rabbits
Br J Nutr, 16, 497-506
DOI 10.1079/bjn19620048, PubMed 13960279
The influence of ethyl linoleate and ethyl linolenate on polyenoic fatty acids and cholesterol in tissues of chicks
Z Ernahrungswiss, 2, 223-8
DOI 10.1007/BF02020814, PubMed 13908506
Polyenoic fatty acids and cholesterol in chicks given 9-cis-12-cis linoleate, 9-trans-12-trans linoleate or 9-trans-11-trans linoleate
Br J Nutr, 16, 379-86
DOI 10.1079/bjn19620039, PubMed 14036317
Publications 1961
Serum lipids in relation to the intake of alcohol and sodium chloride
Nature, 191, 1095-7
DOI 10.1038/1911095a0, PubMed 13764263
Publications 1960
Polyenoic fatty acids and cholesterol in blood, heart and liver of chicks fed on hydrogenated and unhydrogenated arachis oil
Br J Nutr, 14, 247-54
DOI 10.1079/bjn19600030, PubMed 14402773
Publications 1959
Influence of dietary cholesterol, cod liver oil and linseed oil on cholesterol and polyenoic fatty acids in tissues from fasted and non-fasted chicks
Acta Physiol Scand, 45 (1), 31-42
DOI 10.1111/j.1748-1716.1959.tb01676.x, PubMed 13626602
Publications 1958
Influence of dietary hydrogenated peanut oil and cholesterol on cholesterol and polyenoic fatty acids in tissues of chicks
Acta Physiol Scand, 43 (2), 97-104
DOI 10.1111/j.1748-1716.1958.tb01580.x, PubMed 13570996
Effect of pyridoxine deficiency on cholesterol and polyenoic fatty acids in chicks
Acta Physiol Scand, 44 (1), 67-79
DOI 10.1111/j.1748-1716.1958.tb01609.x, PubMed 13605808
Publications 1956
Alimentary production of gallstones in hamsters. 6. Disappearance of cholesterol stones by treatment with a non-lithogenic diet
Acta Physiol Scand, 36 (4), 329-36
DOI 10.1111/j.1748-1716.1956.tb01329.x, PubMed 13313230
Influence of varied levels of peanut oil and cholesterol on cholesterol and polyenoic acids in tissues of the chicks
Acta Physiol Scand, 36 (4), 319-28
DOI 10.1111/j.1748-1716.1956.tb01328.x, PubMed 13313229