Maria Ekman Stensland
- Proteomics Service Manager; PhD
- +47 23073037
Maria started as the Head engineer at PCF in 2010. Before that, she performed her PhD thesis at the Department of Immunology, University of Oslo with topic ‘Peptidylarginine deiminase 4 and citrullination in Rheumatoid arthritis’. She has more than ten years of experience in high-resolution nanoLC-MS/MS, and is experienced with most LC-MS/MS based proteomics workflows.
Publications 2024
Benchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling
NPJ Syst Biol Appl, 10 (1), 73
DOI 10.1038/s41540-024-00402-z, PubMed 38997321
Publications 2023
Lipopolysaccharide Primes Human Macrophages for Noncanonical Inflammasome-Induced Extracellular Vesicle Secretion
J Immunol, 210 (3), 322-334
DOI 10.4049/jimmunol.2200444, PubMed 36525001
Bacterial Brain Abscesses Expand Despite Effective Antibiotic Treatment: A Process Powered by Osmosis Due to Neutrophil Cell Death
Neurosurgery, 94 (5), 1079-87 (in press)
DOI 10.1227/neu.0000000000002792, PubMed 38084989
Comparison between articular chondrocytes and mesenchymal stromal cells for the production of articular cartilage implants
Front Bioeng Biotechnol, 11, 1116513
DOI 10.3389/fbioe.2023.1116513, PubMed 36896010
A homozygous POLR1A variant causes leukodystrophy and affects protein homeostasis
Brain, 146 (8), 3513-3527
DOI 10.1093/brain/awad086, PubMed 36917474
Identifying a core protein signature of small extracellular vesicles derived from B-cell precursor acute lymphoblastic leukaemia
Scand J Immunol, 99 (3), e13341
DOI 10.1111/sji.13341, PubMed 38441169
Publications 2022
Identification of a Phage Display-Derived Peptide Interacting with the N-Terminal Region of Factor VII Activating Protease (FSAP) Enables Characterization of Zymogen Activation
ACS Chem Biol, 17 (9), 2631-2642
DOI 10.1021/acschembio.2c00538, PubMed 36070465
Glioblastoma microenvironment contains multiple hormonal and non-hormonal growth-stimulating factors
Fluids Barriers CNS, 19 (1), 45
DOI 10.1186/s12987-022-00333-z, PubMed 35659255
Isolation of a cytolytic subpopulation of extracellular vesicles derived from NK cells containing NKG7 and cytolytic proteins
Front Immunol, 13, 977353
DOI 10.3389/fimmu.2022.977353, PubMed 36189227
Publications 2021
Immune complexes, innate immunity, and NETosis in ChAdOx1 vaccine-induced thrombocytopenia
Eur Heart J, 42 (39), 4064-4072
DOI 10.1093/eurheartj/ehab506, PubMed 34405870
Proteomic study of apheresis platelets made HLA class I deficient for transfusion of refractory patients
Proteomics Clin Appl, 15 (6), e2100022
DOI 10.1002/prca.202100022, PubMed 34510746
Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
Carcinogenesis, 42 (5), 685-693
DOI 10.1093/carcin/bgab015, PubMed 33609362
In Well-Treated Celiac Patients Low-Level Mucosal Inflammation Predicts Response to 14-day Gluten Challenge
Adv Sci (Weinh), 8 (4), 2003526
DOI 10.1002/advs.202003526, PubMed 33643806
Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk
Sci Rep, 11 (1), 21936
DOI 10.1038/s41598-021-01334-y, PubMed 34754007
Design of a Proteolytically Stable Sodium-Calcium Exchanger 1 Activator Peptide for In Vivo Studies
Front Pharmacol, 12, 638646
DOI 10.3389/fphar.2021.638646, PubMed 34163352
Publications 2020
The Cardiac Syndecan-2 Interactome
Front Cell Dev Biol, 8, 792
DOI 10.3389/fcell.2020.00792, PubMed 32984315
An intact C-terminal end of albumin is required for its long half-life in humans
Commun Biol, 3 (1), 181
DOI 10.1038/s42003-020-0903-7, PubMed 32313072
Publications 2019
Persistence of intrathecal oligoclonal B cells and IgG in multiple sclerosis
J Neuroimmunol, 333, 576966
DOI 10.1016/j.jneuroim.2019.576966, PubMed 31153015
Publications 2018
A high-throughput pipeline for validation of antibodies
Nat Methods, 15 (11), 909-912
DOI 10.1038/s41592-018-0179-8, PubMed 30377371
Publications 2017
The proteome of pus from human brain abscesses: host-derived neurotoxic proteins and the cell-type diversity of CNS pus
J Neurosurg, 129 (3), 829-837
DOI 10.3171/2017.4.JNS17284, PubMed 29053067
Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins
Cell Rep, 20 (10), 2357-2367
DOI 10.1016/j.celrep.2017.08.036, PubMed 28877470
Publications 2016
Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein
Kidney Int Rep, 2 (3), 461-469
DOI 10.1016/j.ekir.2016.11.005, PubMed 29142973
Comparative protein profiling of B16 mouse melanoma cells susceptible and non-susceptible to alphavirus infection: Effect of the tumor microenvironment
Cancer Biol Ther, 17 (10), 1035-1050
DOI 10.1080/15384047.2016.1219813, PubMed 27636533
Publications 2015
Mechanisms underlying AQP4 accumulation in astrocyte endfeet
Glia, 63 (11), 2073-2091
DOI 10.1002/glia.22878, PubMed 26119521
Publications 2012
APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration
Mol Biol Cell, 23 (11), 2109-21
DOI 10.1091/mbc.E10-12-1000, PubMed 22496417
Publications 2011
TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer
Nat Commun, 2, 330
DOI 10.1038/ncomms1332, PubMed 21629263
Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate
Rheumatol Int, 32 (5), 1271-6
DOI 10.1007/s00296-010-1765-y, PubMed 21267570
Publications 2009
Targeted analysis of protein citrullination using chemical modification and tandem mass spectrometry
Rapid Commun Mass Spectrom, 23 (17), 2754-62
DOI 10.1002/rcm.4185, PubMed 19639564
Primary sequence, together with other factors, influence peptide deimination by peptidylarginine deiminase-4
Biol Chem, 390 (2), 99-107
DOI 10.1515/BC.2009.019, PubMed 19040354
Publications 2007
Proteome changes in bovine longissimus thoracis muscle during the early postmortem storage period
J Proteome Res, 6 (7), 2720-31
DOI 10.1021/pr070173o, PubMed 17567165
Publications 2006
TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner
Cell Cycle, 5 (23), 2787-95
DOI 10.4161/cc.5.23.3523, PubMed 17172861
Publications 2004
The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity
Biochem J, 382 (Pt 1), 261-8
DOI 10.1042/BJ20040285, PubMed 15186217
Publications 2002
18S rDNA phylogeny of the Tubificidae (Clitellata) and its constituent taxa: dismissal of the Naididae
Mol Phylogenet Evol, 22 (3), 414-22
DOI 10.1006/mpev.2001.1063, PubMed 11884166