Elisabeth Gulowsen Celius
- Group leader, senior consultant, professor; MD, PhD
- +47 221 19202
Background:
Medical degree from University of Bonn, Germany 1985, certified in neurology 1993. PhD in 1986. Has worked as a consultant with a special focus on MS at the Oslo University Hospital since 1987. Group leader of the MS Research group from September 2018. Head of the Neurological department 2002-2010. Head of the out-patient clinic at OUS 2010-2018. Member of the steering group of the National MS-Registry, member of reference group preparing guidelines for treatment of MS and priorities Norwegian Directorate of Health, previous member of ECTRIMS Council. Member of steering committees in international trials and national investigator in several trials.
Project/Research interest:
Leader of the MS clinic and the MS team. Special interest in MS epidemiology and clinical studies, but also participating in genetic studies and gene-environment studies. Takes actively part in the development of local, national and international data collections and research projects.
Publications 2024
Grey Matter Atrophy and its Relationship with White Matter Lesions in Patients with Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease, Aquaporin-4 Antibody-Positive Neuromyelitis Optica Spectrum Disorder, and Multiple Sclerosis
Ann Neurol, 96 (2), 276-288
DOI 10.1002/ana.26951, PubMed 38780377
COVID-19 and multiple sclerosis: challenges and lessons for patient care
Lancet Reg Health Eur, 44, 100979
DOI 10.1016/j.lanepe.2024.100979, PubMed 39429966
Publications 2023
The instrumented single leg stance test detects early balance impairment in people with multiple sclerosis
Front Neurol, 14, 1227374
DOI 10.3389/fneur.2023.1227374, PubMed 37538255
"No association between disease modifying treatment and fatigue in multiple sclerosis"
Mult Scler Relat Disord, 79, 104993
DOI 10.1016/j.msard.2023.104993, PubMed 37708819
Clinical and MRI measures to identify non-acute MOG-antibody disease in adults
Brain, 146 (6), 2489-2501
DOI 10.1093/brain/awac480, PubMed 36515653
T cell responses to SARS-CoV-2 vaccination differ by disease-modifying therapy for multiple sclerosis
JCI Insight, 8 (12)
DOI 10.1172/jci.insight.165111, PubMed 37159281
Publications 2022
Sensor-based gait analyses of the six-minute walk test identify qualitative improvement in gait parameters of people with multiple sclerosis after rehabilitation
J Neurol, 269 (7), 3723-3734
DOI 10.1007/s00415-022-10998-z, PubMed 35166925
Fatigue in multiple sclerosis is associated with socioeconomic factors
Mult Scler Relat Disord, 64, 103955
DOI 10.1016/j.msard.2022.103955, PubMed 35753177
Exploring Retinal Blood Vessel Diameters as Biomarkers in Multiple Sclerosis
J Clin Med, 11 (11)
DOI 10.3390/jcm11113109, PubMed 35683496
Abuse and revictimization in adulthood in multiple sclerosis: a cross-sectional study during pregnancy
J Neurol, 269 (11), 5901-5909
DOI 10.1007/s00415-022-11249-x, PubMed 35780399
Association of adverse childhood experiences with the development of multiple sclerosis
J Neurol Neurosurg Psychiatry, 93 (6), 645-650
DOI 10.1136/jnnp-2021-328700, PubMed 35379699
The influence of socioeconomic factors on access to disease modifying treatment in a Norwegian multiple sclerosis cohort
Mult Scler Relat Disord, 61, 103759
DOI 10.1016/j.msard.2022.103759, PubMed 35358792
Cancer related mortality in multiple sclerosis. A population based cohort study
Mult Scler Relat Disord, 69, 104417
DOI 10.1016/j.msard.2022.104417, PubMed 36423459
Deep neural networks learn general and clinically relevant representations of the ageing brain
Neuroimage, 256, 119210
DOI 10.1016/j.neuroimage.2022.119210, PubMed 35462035
Risk of fingolimod rebound after switching to cladribine or rituximab in multiple sclerosis
Mult Scler Relat Disord, 62, 103812
DOI 10.1016/j.msard.2022.103812, PubMed 35462167
Expert opinion on the long-term use of cladribine tablets for multiple sclerosis: Systematic literature review of real-world evidence
Mult Scler Relat Disord, 69, 104459
DOI 10.1016/j.msard.2022.104459, PubMed 36565573
Rebaseline no evidence of disease activity (NEDA-3) as a predictor of long-term disease course in a Norwegian multiple sclerosis population
Front Neurol, 13, 1034056
DOI 10.3389/fneur.2022.1034056, PubMed 36452173
Publications 2021
High prevalence of fatigue in contemporary patients with multiple sclerosis
Mult Scler J Exp Transl Clin, 7 (1), 2055217321999826
DOI 10.1177/2055217321999826, PubMed 33796331
Disease Progression in Multiple Sclerosis: A Literature Review Exploring Patient Perspectives
Patient Prefer Adherence, 15, 15-27
DOI 10.2147/PPA.S268829, PubMed 33447018
Maternal education has significant influence on progression in multiple sclerosis
Mult Scler Relat Disord, 53, 103052
DOI 10.1016/j.msard.2021.103052, PubMed 34111658
Incidence of cancer in multiple sclerosis before and after the treatment era- a registry- based cohort study
Mult Scler Relat Disord, 55, 103209
DOI 10.1016/j.msard.2021.103209, PubMed 34419754
Management of Severe Graves' Hyperthyroidism in Pregnancy Following Immune Reconstitution Therapy in Multiple Sclerosis
J Endocr Soc, 5 (6), bvab044
DOI 10.1210/jendso/bvab044, PubMed 34017934
Humoral immunity to SARS-CoV-2 mRNA vaccination in multiple sclerosis: the relevance of time since last rituximab infusion and first experience from sporadic revaccinations
J Neurol Neurosurg Psychiatry, 94 (1), 19-22
DOI 10.1136/jnnp-2021-327612, PubMed 34670844
Factors associated with treatment escalation among MS specialists and general neurologists: Results from an International cojoint study
Mult Scler Relat Disord, 58, 103404
DOI 10.1016/j.msard.2021.103404, PubMed 35216786
Effect of desire for pregnancy on decisions to escalate treatment in multiple sclerosis care: Differences between MS specialists and non-MS specialists
Mult Scler Relat Disord, 57, 103389
DOI 10.1016/j.msard.2021.103389, PubMed 35158479
Early High Efficacy Treatment in Multiple Sclerosis Is the Best Predictor of Future Disease Activity Over 1 and 2 Years in a Norwegian Population-Based Registry
Front Neurol, 12, 693017
DOI 10.3389/fneur.2021.693017, PubMed 34220694
No significant differences in absenteeism or academic achievements in a Norwegian multiple sclerosis case control study
Mult Scler Relat Disord, 54, 103141
DOI 10.1016/j.msard.2021.103141, PubMed 34273610
Publications 2020
Quality of Life Improves with Alemtuzumab Over 6 Years in Relapsing-Remitting Multiple Sclerosis Patients with or without Autoimmune Thyroid Adverse Events: Post Hoc Analysis of the CARE-MS Studies
Neurol Ther, 9 (2), 443-457
DOI 10.1007/s40120-020-00191-7, PubMed 32410147
CD8+ T cell gene expression analysis identifies differentially expressed genes between multiple sclerosis patients and healthy controls
Mult Scler J Exp Transl Clin, 6 (4), 2055217320978511
DOI 10.1177/2055217320978511, PubMed 33343920
Breastfeeding and treatment of multiple sclerosis
Mult Scler, 27 (5), 801-802
DOI 10.1177/1352458520931786, PubMed 32507035
Normal antibody response after COVID-19 during treatment with cladribine
Mult Scler Relat Disord, 46, 102476
DOI 10.1016/j.msard.2020.102476, PubMed 32882501
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Nat Commun, 11 (1), 4016
DOI 10.1038/s41467-020-17376-1, PubMed 32782260
Prevalence of multiple sclerosis in rural and urban districts in Telemark county, Norway
Mult Scler Relat Disord, 45, 102352
DOI 10.1016/j.msard.2020.102352, PubMed 32707528
Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 23 (2), 295
DOI 10.1038/s41593-019-0553-6, PubMed 31848485
Pregnancy outcomes and postpartum relapse rates in women with RRMS treated with alemtuzumab in the phase 2 and 3 clinical development program over 16 years
Mult Scler Relat Disord, 43, 102146
DOI 10.1016/j.msard.2020.102146, PubMed 32498033
Chronic fatigue and depression due to multiple sclerosis: Immune-inflammatory pathways, tryptophan catabolites and the gut-brain axis as possible shared pathways
Mult Scler Relat Disord, 46, 102533
DOI 10.1016/j.msard.2020.102533, PubMed 33010585
State of the Art and Future Challenges in Multiple Sclerosis Research and Medical Management: An Insight into the 5th International Porto Congress of Multiple Sclerosis
Neurol Ther, 9 (2), 281-300
DOI 10.1007/s40120-020-00202-7, PubMed 32666470
The course of multiple sclerosis rewritten: a Norwegian population-based study on disease demographics and progression
J Neurol, 268 (4), 1330-1341
DOI 10.1007/s00415-020-10279-7, PubMed 33090270
The diagnostic value of IgG index versus oligoclonal bands in cerebrospinal fluid of patients with multiple sclerosis
Mult Scler J Exp Transl Clin, 6 (1), 2055217319901291
DOI 10.1177/2055217319901291, PubMed 32030196
Publications 2019
Best Practices for Long-Term Monitoring and Follow-Up of Alemtuzumab-Treated MS Patients in Real-World Clinical Settings
Front Neurol, 10, 253
DOI 10.3389/fneur.2019.00253, PubMed 30967831
No differential gene expression for CD4+ T cells of MS patients and healthy controls
Mult Scler J Exp Transl Clin, 5 (2), 2055217319856903
DOI 10.1177/2055217319856903, PubMed 31223483
Neurodegenerative Interplay of Cardiovascular Autonomic Dysregulation and the Retina in Early Multiple Sclerosis
Front Neurol, 10, 507
DOI 10.3389/fneur.2019.00507, PubMed 31156539
Risk of cancer among multiple sclerosis patients, siblings, and population controls: A prospective cohort study
Mult Scler, 26 (12), 1569-1580
DOI 10.1177/1352458519877244, PubMed 31573834
Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 22 (10), 1617-1623
DOI 10.1038/s41593-019-0471-7, PubMed 31551603
Two cases of diabetes mellitus type 1 after alemtuzumab treatment for multiple sclerosis: another probable secondary autoimmune disease
J Neurol, 266 (5), 1270-1271
DOI 10.1007/s00415-019-09257-5, PubMed 30805797
Publications 2018
[Teaching has low academic status]
Tidsskr Nor Laegeforen, 138 (12)
DOI 10.4045/tidsskr.18.0341, PubMed 30132612
Teaching has a low status within academia
Tidsskr. Nor. Laegeforen., 138 (12), 1155
The influence of THC:CBD oromucosal spray on driving ability in patients with multiple sclerosis-related spasticity
Brain Behav, 8 (5), e00962
DOI 10.1002/brb3.962, PubMed 29761015
International consensus on quality standards for brain health-focused care in multiple sclerosis
Mult Scler, 25 (13), 1809-1818
DOI 10.1177/1352458518809326, PubMed 30381987
DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis
Nat Commun, 9 (1), 2397
DOI 10.1038/s41467-018-04732-5, PubMed 29921915
Increased DNA methylation of SLFN12 in CD4+ and CD8+ T cells from multiple sclerosis patients
PLoS One, 13 (10), e0206511
DOI 10.1371/journal.pone.0206511, PubMed 30379917
Restriction spectrum imaging of white matter and its relation to neurological disability in multiple sclerosis
Mult Scler, 25 (5), 687-698
DOI 10.1177/1352458518765671, PubMed 29542336
Publications 2017
Infections in patients with multiple sclerosis: Implications for disease-modifying therapy
Acta Neurol Scand, 136 Suppl 201, 34-36
DOI 10.1111/ane.12835, PubMed 29068490
Preface
Acta Neurol Scand, 136 Suppl 201, 3
DOI 10.1111/ane.12842, PubMed 29068489
Fatigue and cognition: Pupillary responses to problem-solving in early multiple sclerosis patients
Brain Behav, 7 (7), e00717
DOI 10.1002/brb3.717, PubMed 28729927
Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations
NPJ Genom Med, 2, 24
DOI 10.1038/s41525-017-0027-2, PubMed 29263835
Magnetic resonance imaging perfusion is associated with disease severity and activity in multiple sclerosis
Neuroradiology, 59 (7), 655-664
DOI 10.1007/s00234-017-1849-4, PubMed 28585082
Is the hygiene hypothesis relevant for the risk of multiple sclerosis?
Acta Neurol Scand, 136 Suppl 201, 26-30
DOI 10.1111/ane.12844, PubMed 29068485
Publications 2016
The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells
Genes Immun, 17 (2), 118-27
DOI 10.1038/gene.2015.61, PubMed 26765264
Level of education and multiple sclerosis risk over a 50-year period: Registry-based sibling study
Mult Scler, 23 (2), 213-219
DOI 10.1177/1352458516646863, PubMed 27207453
From genetic associations to functional studies in multiple sclerosis
Eur J Neurol, 23 (5), 847-53
DOI 10.1111/ene.12981, PubMed 26948534
Preface
Acta Neurol Scand, 134 Suppl 200, 3
DOI 10.1111/ane.12653, PubMed 27580898
Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies
Neurol Genet, 2 (4), e87
DOI 10.1212/NXG.0000000000000087, PubMed 27540591
Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies
Neurol.-Genet., 2 (4), eB7
DOI 10.1212/NXG.00000000000000B7
Migraine and frequent tension-type headache are not associated with multiple sclerosis in a Norwegian case-control study
Mult Scler J Exp Transl Clin, 2, 2055217316682976
DOI 10.1177/2055217316682976, PubMed 28607748
[Not Available]
Tidsskr Nor Laegeforen, 136 (19), 1608
DOI 10.4045/tidsskr.16.0826, PubMed 27790879
[Not Available]
Tidsskr Nor Laegeforen, 136 (20), 1702
DOI 10.4045/tidsskr.16.0865, PubMed 27830899
[MRI in multiple sclerosis]
Tidsskr Nor Laegeforen, 136 (16), 1373-6
DOI 10.4045/tidsskr.15.1361, PubMed 27637059
MRI- investigations in multiple sclerosis
Tidsskr. Nor. Laegeforen., 136 (16), 1373-1376
Bone mineral density in patients with multiple sclerosis, hereditary ataxia or hereditary spastic paraplegia after at least 10 years of disease - a case control study
BMC Neurol, 16 (1), 252
DOI 10.1186/s12883-016-0771-4, PubMed 27919248
High prevalence and increasing incidence of multiple sclerosis in the Norwegian county of Buskerud
Acta Neurol Scand, 135 (4), 412-418
DOI 10.1111/ane.12615, PubMed 27241360
Publications 2015
Socio-economic factors and immigrant population studies of multiple sclerosis
Acta Neurol Scand, 132 (199), 37-41
DOI 10.1111/ane.12429, PubMed 26046557
Comments on the review article 'Time trends in the incidence and prevalence of multiple sclerosis in Norway during eight decades'
Acta Neurol Scand, 132 (5), 364-7
DOI 10.1111/ane.12489, PubMed 26423981
Genetic variants are major determinants of CSF antibody levels in multiple sclerosis
Brain, 138 (Pt 3), 632-43
DOI 10.1093/brain/awu405, PubMed 25616667
Multiple Sclerosis Risk Allele in CLEC16A Acts as an Expression Quantitative Trait Locus for CLEC16A and SOCS1 in CD4+ T Cells
PLoS One, 10 (7), e0132957
DOI 10.1371/journal.pone.0132957, PubMed 26203907
Class II HLA interactions modulate genetic risk for multiple sclerosis
Nat Genet, 47 (10), 1107-1113
DOI 10.1038/ng.3395, PubMed 26343388
A Longitudinal Study of Disability, Cognition and Gray Matter Atrophy in Early Multiple Sclerosis Patients According to Evidence of Disease Activity
PLoS One, 10 (8), e0135974
DOI 10.1371/journal.pone.0135974, PubMed 26280173
Eye and hand motor interactions with the Symbol Digit Modalities Test in early multiple sclerosis
Mult Scler Relat Disord, 4 (6), 585-9
DOI 10.1016/j.msard.2015.08.003, PubMed 26590666
Improvement in Fatigue during Natalizumab Treatment is Linked to Improvement in Depression and Day-Time Sleepiness
Front Neurol, 6, 18
DOI 10.3389/fneur.2015.00018, PubMed 25755648
Reduced perfusion in white matter lesions in multiple sclerosis
Eur J Radiol, 84 (12), 2605-12
DOI 10.1016/j.ejrad.2015.09.007, PubMed 26391230
Publications 2014
High prevalence and no latitude gradient of multiple sclerosis in Norway
Mult Scler, 20 (13), 1780-2
DOI 10.1177/1352458514525871, PubMed 24603884
Prevalence of multiple sclerosis among immigrants in Norway
Mult Scler, 21 (6), 695-702
DOI 10.1177/1352458514554055, PubMed 25344371
No association between multiple sclerosis and periodontitis after adjusting for smoking habits
Eur J Neurol, 22 (3), 588-90
DOI 10.1111/ene.12520, PubMed 25041906
Environmental exposures and the risk of multiple sclerosis investigated in a Norwegian case-control study
BMC Neurol, 14, 196
DOI 10.1186/s12883-014-0196-x, PubMed 25274070
Oligoclonal band phenotypes in MS differ in their HLA class II association, while specific KIR ligands at HLA class I show association to MS in general
J Neuroimmunol, 274 (1-2), 174-9
DOI 10.1016/j.jneuroim.2014.06.024, PubMed 25037176
Multiple sclerosis and seizures: incidence and prevalence over 40 years
Acta Neurol Scand, 130 (6), 368-73
DOI 10.1111/ane.12276, PubMed 25209977
Cortical thickness and surface area relate to specific symptoms in early relapsing-remitting multiple sclerosis
Mult Scler, 21 (4), 402-14
DOI 10.1177/1352458514543811, PubMed 25139946
Month of birth and risk of multiple sclerosis: confounding and adjustments
Ann Clin Transl Neurol, 1 (2), 141-4
DOI 10.1002/acn3.37, PubMed 25356394
Reply to comment: Month of birth and risk of multiple sclerosis: confounding and adjustments
Ann Clin Transl Neurol, 1 (5), 376-7
DOI 10.1002/acn3.56, PubMed 25356407
Clinical case reviews and poster sessions in multiple sclerosis spasticity: main outcomes and highlights
Eur Neurol, 72 Suppl 1, 15-9
DOI 10.1159/000367619, PubMed 25278119
Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort
Eur J Hum Genet, 23 (5), 688-92
DOI 10.1038/ejhg.2014.155, PubMed 25159868
Publications 2013
No evidence of association between mutant alleles of the CYP27B1 gene and multiple sclerosis
Ann Neurol, 73 (3), 430-2
DOI 10.1002/ana.23833, PubMed 23444327
Increased disease severity in non-Western immigrants with multiple sclerosis in Oslo, Norway
Eur J Neurol, 20 (12), 1546-52
DOI 10.1111/ene.12227, PubMed 23834430
Oligoclonal bands and age at onset correlate with genetic risk score in multiple sclerosis
Mult Scler, 20 (6), 660-8
DOI 10.1177/1352458513506503, PubMed 24099750
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
Nat Genet, 45 (11), 1353-60
DOI 10.1038/ng.2770, PubMed 24076602
Sex ratio of multiple sclerosis in persons born from 1930 to 1979 and its relation to latitude in Norway
J Neurol, 260 (6), 1481-8
DOI 10.1007/s00415-012-6814-x, PubMed 23292231
Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients
PLoS One, 8 (6), e64408
DOI 10.1371/journal.pone.0064408, PubMed 23785401
Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles
PLoS One, 8 (3), e58352
DOI 10.1371/journal.pone.0058352, PubMed 23472185
Natalizumab treatment reduces fatigue in multiple sclerosis. Results from the TYNERGY trial; a study in the real life setting
PLoS One, 8 (3), e58643
DOI 10.1371/journal.pone.0058643, PubMed 23555589
Publications 2012
Association between DPP6 polymorphism and the risk of progressive multiple sclerosis in Northern and Southern Europeans
Neurosci Lett, 530 (2), 155-60
DOI 10.1016/j.neulet.2012.10.008, PubMed 23069673
Month of birth as a latitude-dependent risk factor for multiple sclerosis in Norway
Mult Scler, 19 (8), 1028-34
DOI 10.1177/1352458512471094, PubMed 23257620
Importance of human leukocyte antigen (HLA) class I and II alleles on the risk of multiple sclerosis
PLoS One, 7 (5), e36779
DOI 10.1371/journal.pone.0036779, PubMed 22586495
Polymorphisms of the BDNF gene show neither association with multiple sclerosis susceptibility nor clinical course
J Neuroimmunol, 244 (1-2), 107-10
DOI 10.1016/j.jneuroim.2012.01.011, PubMed 22341604
Bone turnover and metabolism in patients with early multiple sclerosis and prevalent bone mass deficit: a population-based case-control study
PLoS One, 7 (9), e45703
DOI 10.1371/journal.pone.0045703, PubMed 23029191
Publications 2011
Genetic association of multiple sclerosis with the marker rs391745 near the endogenous retroviral locus HERV-Fc1: analysis of disease subtypes
PLoS One, 6 (10), e26438
DOI 10.1371/journal.pone.0026438, PubMed 22039488
[New gene map for multiple sclerosis]
Tidsskr Nor Laegeforen, 131 (21), 2126-30
DOI 10.4045/tidsskr.10.0823, PubMed 22048209
[Development of new therapies for multiple sclerosis]
Tidsskr Nor Laegeforen, 131 (8), 832-6
DOI 10.4045/tidsskr.10.0077, PubMed 21556088
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Nature, 476 (7359), 214-9
DOI 10.1038/nature10251, PubMed 21833088
No influence on disease progression of non-HLA susceptibility genes in MS
J Neuroimmunol, 237 (1-2), 98-100
DOI 10.1016/j.jneuroim.2011.05.003, PubMed 21742385
Fractures and falls in patients with newly diagnosed clinically isolated syndrome and multiple sclerosis
Acta Neurol Scand Suppl (191), 79-82
DOI 10.1111/j.1600-0404.2011.01548.x, PubMed 21711261
Low bone mass in newly diagnosed multiple sclerosis and clinically isolated syndrome
Neurology, 77 (2), 151-7
DOI 10.1212/WNL.0b013e3182242d34, PubMed 21747073
[Treatment of stroke--an interdisciplinary challenge]
Tidsskr Nor Laegeforen, 131 (9-10), 934-6
DOI 10.4045/tidsskr.11.0424, PubMed 21606987
Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655
Eur J Hum Genet, 19 (10), 1100-3
DOI 10.1038/ejhg.2011.88, PubMed 21610746
Publications 2010
IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation
J Immunol, 185 (11), 6883-90
DOI 10.4049/jimmunol.1001392, PubMed 21041731
[Treatment of multiple sclerosis]
Tidsskr Nor Laegeforen, 130 (9), 923; author reply 923
DOI 10.4045/tidsskr.10.0346, PubMed 20453948
Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis
Nat Genet, 42 (6), 469-70; author reply 470-1
DOI 10.1038/ng0610-469, PubMed 20502484
Two HLA class I genes independently associated with multiple sclerosis
J Neuroimmunol, 226 (1-2), 172-6
DOI 10.1016/j.jneuroim.2010.07.006, PubMed 20678810
Association to the Glypican-5 gene in multiple sclerosis
J Neuroimmunol, 226 (1-2), 194-7
DOI 10.1016/j.jneuroim.2010.07.003, PubMed 20692050
Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus
Genes Immun, 12 (3), 191-8
DOI 10.1038/gene.2010.59, PubMed 21179112
Methylprednisolone in combination with interferon beta-1a for relapsing-remitting multiple sclerosis (MECOMBIN study): a multicentre, double-blind, randomised, placebo-controlled, parallel-group trial
Lancet Neurol, 9 (7), 672-80
DOI 10.1016/S1474-4422(10)70132-0, PubMed 20542736
Publications 2009
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor
Eur J Hum Genet, 17 (10), 1309-13
DOI 10.1038/ejhg.2009.41, PubMed 19293837
Change in sex ratio, disease course and age at diagnosis in Oslo MS patients through seven decades
Acta Neurol Scand Suppl (189), 27-9
DOI 10.1111/j.1600-0404.2009.01208.x, PubMed 19566494
MYO9B polymorphisms in multiple sclerosis
Eur J Hum Genet, 17 (6), 840-3
DOI 10.1038/ejhg.2008.251, PubMed 19142207
Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis
Ann Neurol, 65 (6), 658-66
DOI 10.1002/ana.21695, PubMed 19630074
A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis
Eur J Hum Genet, 18 (4), 502-4
DOI 10.1038/ejhg.2009.195, PubMed 19888296
Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis
Genes Immun, 11 (2), 142-54
DOI 10.1038/gene.2009.82, PubMed 19865101
Excess mortality and cause of death in a cohort of Norwegian multiple sclerosis patients
Mult Scler, 15 (11), 1263-70
DOI 10.1177/1352458509107010, PubMed 19812114
Cognitive impairment after three decades of multiple sclerosis
Eur J Neurol, 17 (3), 499-505
DOI 10.1111/j.1468-1331.2009.02889.x, PubMed 20050887
Publications 2008
Cost-effectiveness of natalizumab in multiple sclerosis
Expert Rev Pharmacoecon Outcomes Res, 8 (1), 11-21
DOI 10.1586/14737167.8.1.11, PubMed 20528351
Perceptions of illness and its development in patients with multiple sclerosis: a prospective cohort study
J Adv Nurs, 65 (1), 184-92
DOI 10.1111/j.1365-2648.2008.04862.x, PubMed 19032506
The SH2D2A gene and susceptibility to multiple sclerosis
J Neuroimmunol, 197 (2), 152-8
DOI 10.1016/j.jneuroim.2008.04.037, PubMed 18554728
Publications 2007
Multippel sklerose: er det sykdommen som skal styre livet?
In Pasienten og sykdommen: psykiske faktorer ved somatisk sykdom, Gyldendal akademisk, Oslo, S. 135-141
BIBSYS 071388192
A follow-up study of Nordic multiple sclerosis candidate gene regions
Mult Scler, 13 (5), 584-9
DOI 10.1177/1352458506071790, PubMed 17548436
Low frequency of the disease-associated DRB1*15-DQB1*06 haplotype may contribute to the low prevalence of multiple sclerosis in Sami
Tissue Antigens, 69 (4), 299-304
DOI 10.1111/j.1399-0039.2007.00803.x, PubMed 17389012
Familial effects on the clinical course of multiple sclerosis
Neurology, 68 (5), 376-83
DOI 10.1212/01.wnl.0000252822.53506.46, PubMed 17261686
[Incorrect information about treatment of multiple sclerosis from the Knowledge Center]
Tidsskr Nor Laegeforen, 127 (12), 1672-3; author reply 1673
PubMed 17571115
[A rush job and knowledge handling]
Tidsskr Nor Laegeforen, 127 (15), 1961-2
PubMed 17700745
X chromosome inactivation in females with multiple sclerosis
Eur J Neurol, 14 (12), 1392-6
DOI 10.1111/j.1468-1331.2007.01987.x, PubMed 17970735
A prospective study of patterns of fatigue in multiple sclerosis
Eur J Neurol, 14 (12), 1338-43
DOI 10.1111/j.1468-1331.2007.01974.x, PubMed 17903208
Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis
Nat Genet, 39 (9), 1108-13
DOI 10.1038/ng2106, PubMed 17660816
The impact of HLA-A and -DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients
Eur J Neurol, 14 (8), 835-40
DOI 10.1111/j.1468-1331.2007.01825.x, PubMed 17662002
Marked differences in prevalence of multiple sclerosis between ethnic groups in Oslo, Norway
J Neurol, 255 (1), 49-55
DOI 10.1007/s00415-007-0659-8, PubMed 18080855
Publications 2006
Coding region polymorphisms in T cell signal transduction genes. Prevalence and association to development of multiple sclerosis
J Neuroimmunol, 177 (1-2), 40-5
DOI 10.1016/j.jneuroim.2006.04.021, PubMed 16764945
Association analysis of the LAG3 and CD4 genes in multiple sclerosis in two independent populations
J Neuroimmunol, 180 (1-2), 193-8
DOI 10.1016/j.jneuroim.2006.08.009, PubMed 17020785
Publications 2005
Lack of association with the CD28/CTLA4/ICOS gene region among Norwegian multiple sclerosis patients
J Neuroimmunol, 166 (1-2), 197-201
DOI 10.1016/j.jneuroim.2005.06.002, PubMed 16005527
[Optic neuritis--diagnosis, treatment and follow up]
Tidsskr Nor Laegeforen, 125 (4), 425-8 (Retracted)
PubMed 15742012
[Retraction of article]
Tidsskr Nor Laegeforen, 125 (15), 2056
PubMed 16208878
Multiple Sclerosis Severity Score: using disability and disease duration to rate disease severity
Neurology, 64 (7), 1144-51
DOI 10.1212/01.WNL.0000156155.19270.F8, PubMed 15824338
Publications 2004
Å leve med MS
Biogen IDEC Norge, Oslo, 31 s.
BIBSYS 041575970
Hva er MS?
Biogen Idec, Oslo (Oppdatert juni 2004), 38 s.
BIBSYS 061633496
Psykologi og MS
Biogen Idec, Oslo (Oppdatert juni 2004), 38 s.
BIBSYS 06163350x
Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis
Tissue Antigens, 63 (3), 237-47
DOI 10.1111/j.0001-2815.2004.00173.x, PubMed 14989713
Depressive symptoms account for deficient information processing speed but not for impaired working memory in early phase multiple sclerosis (MS)
J Neurol Sci, 217 (2), 211-6
DOI 10.1016/j.jns.2003.10.012, PubMed 14706226
Concordance for disease course and age of onset in Scandinavian multiple sclerosis coaffected sib pairs
Mult Scler, 10 (1), 5-8
DOI 10.1191/1352458504ms975oa, PubMed 14760946
Publications 2003
Radon: a possible risk factor in multiple sclerosis
Neuroepidemiology, 22 (1), 87-94
DOI 10.1159/000067102, PubMed 12566959
Two genome-wide linkage disequilibrium screens in Scandinavian multiple sclerosis patients
J Neuroimmunol, 143 (1-2), 101-6
DOI 10.1016/j.jneuroim.2003.08.021, PubMed 14575924
Fatigue and its association with sociodemographic variables among multiple sclerosis patients
Mult Scler, 9 (5), 509-14
DOI 10.1191/1352458503ms943oa, PubMed 14582778
[New diagnostic criteria in multiple sclerosis]
Tidsskr Nor Laegeforen, 123 (10), 1345-8
PubMed 12806674
Publications 2001
Multiple sclerosis in Oslo, Norway: prevalence on 1 January 1995 and incidence over a 25-year period
Eur J Neurol, 8 (5), 463-9
DOI 10.1046/j.1468-1331.2001.00269.x, PubMed 11554910
The T cell regulator gene SH2D2A contributes to the genetic susceptibility of multiple sclerosis
Genes Immun, 2 (5), 263-8
DOI 10.1038/sj.gene.6363774, PubMed 11528519
Publications 2000
Sex and age at diagnosis are correlated with the HLA-DR2, DQ6 haplotype in multiple sclerosis
J Neurol Sci, 178 (2), 132-5
DOI 10.1016/s0022-510x(00)00389-0, PubMed 11018705
Memory functioning and emotional changes in early phase multiple sclerosis
Arch Clin Neuropsychol, 15 (1), 37-46
DOI 10.1016/S0887-6177(98)00151-6, PubMed 14590566
Publications 1999
Hva er MS?
Ariez Pharma Consultancy, Amsterdam, 38 s.
BIBSYS 011580623
Psykologi og MS
Ariez Pharma Consultancy, Amsterdam, 38 s.
BIBSYS 020852878
Å leve med MS
Biogen, Amsterdam], 28 s.
BIBSYS 020853440
CTLA4 promoter and exon 1 dimorphisms in multiple sclerosis
Tissue Antigens, 53 (1), 106-10
DOI 10.1034/j.1399-0039.1999.530112.x, PubMed 10082437
Interferon-alpha2a reduces MRI disease activity in relapsing-remitting multiple sclerosis. Norwegian Study Group on Interferon-alpha in Multiple Sclerosis
Neurology, 52 (5), 1049-56
DOI 10.1212/wnl.52.5.1049, PubMed 10102427
Publications 1998
[Differences in morbidity between the Eastern central city district and the suburban Western district of Oslo]
Tidsskr Nor Laegeforen, 118 (1), 14-7
PubMed 9481903
Publications 1997
[Neurologic complications in heroin abuse. Illustrated by two unusual cases]
Tidsskr Nor Laegeforen, 117 (3), 356-7
PubMed 9064856
The HLA-DQ(alpha 1*0102, beta 1*0602) heterodimer may confer susceptibility to multiple sclerosis in the absence of the HLA-DR(alpha 1*01, beta 1*1501) heterodimer
Tissue Antigens, 50 (1), 15-22
DOI 10.1111/j.1399-0039.1997.tb02828.x, PubMed 9243750
Publications 1996
Leucoencephalopathy after inhalation of heroin: a case report
J Neurol Neurosurg Psychiatry, 60 (6), 694-5
DOI 10.1136/jnnp.60.6.694, PubMed 8648344