Håvard Fretheim

  • Researcher; MD, PhD
 

Publications 2022

Didriksen H, Molberg Ø, Mehta A, Jordan S, Palchevskiy V, Fretheim H, Gude E, Ueland T, Brunborg C, Garen T, Midtvedt Ø, Andreassen AK, Lund-Johansen F, Distler O, Belperio J, Hoffmann-Vold AM (2022)
Target organ expression and biomarker characterization of chemokine CCL21 in systemic sclerosis associated pulmonary arterial hypertension
Front Immunol, 13, 991743
DOI 10.3389/fimmu.2022.991743, PubMed 36211384

Hilberg O, Hoffmann-Vold AM, Smith V, Bouros D, Kilpeläinen M, Guiot J, Morais A, Clemente S, Daniil Z, Papakosta D, Fretheim H, Neves S, Alfaro TM, Antoniou KM, Valveny N, Asijee G, Soulard S, Wuyts W (2022)
Epidemiology of interstitial lung diseases and their progressive-fibrosing behaviour in six European countries
ERJ Open Res, 8 (1)
DOI 10.1183/23120541.00597-2021, PubMed 35083316

Schniering J, Maciukiewicz M, Gabrys HS, Brunner M, Blüthgen C, Meier C, Braga-Lagache S, Uldry AC, Heller M, Guckenberger M, Fretheim H, Nakas CT, Hoffmann-Vold AM, Distler O, Frauenfelder T, Tanadini-Lang S, Maurer B (2022)
Computed tomography-based radiomics decodes prognostic and molecular differences in interstitial lung disease related to systemic sclerosis
Eur Respir J, 59 (5)
DOI 10.1183/13993003.04503-2020, PubMed 34649979

Tennøe AH, Murbræch K, Didriksen H, Ueland T, Palchevskiy V, Weigt SS, Fretheim H, Midtvedt Ø, Garen T, Brunborg C, Aukrust P, Molberg Ø, Belperio JA, Hoffmann-Vold AM (2022)
Serum markers of cardiac complications in a systemic sclerosis cohort
Sci Rep, 12 (1), 4661
DOI 10.1038/s41598-022-08815-8, PubMed 35304587

van Leeuwen NM, Boonstra M, Fretheim H, Brunborg C, Midtvedt Ø, Garen T, Molberg Ø, Huizinga TWJ, de Vries-Bouwstra JK, Hoffman-Vold AM (2022)
Gastrointestinal symptom severity and progression in systemic sclerosis
Rheumatology (Oxford), 61 (10), 4024-4034
DOI 10.1093/rheumatology/keac118, PubMed 35238377

Publications 2021

Didriksen H, Molberg Ø, Fretheim H, Gude E, Jordan S, Brunborg C, Palchevskiy V, Garen T, Midtvedt Ø, Andreassen AK, Distler O, Belperio J, Hoffmann-Vold AM (2021)
Association of Lymphangiogenic Factors With Pulmonary Arterial Hypertension in Systemic Sclerosis
Arthritis Rheumatol, 73 (7), 1277-1287
DOI 10.1002/art.41665, PubMed 33497027

Publications 2020

Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393

Fretheim H, Halse AK, Seip M, Bitter H, Wallenius M, Garen T, Salberg A, Brunborg C, Midtvedt Ø, Molberg Ø, Hoffmann-Vold AM (2020)
Multidimensional tracking of phenotypes and organ involvement in a complete nationwide systemic sclerosis cohort
Rheumatology (Oxford), 59 (10), 2920-2929
DOI 10.1093/rheumatology/keaa026, PubMed 32097470

Hoffmann-Vold AM, Fretheim H, Didriksen H, Molberg Ø (2020)
The potential of fecal microbiota transplantation in systemic sclerosis
Expert Rev Clin Immunol, 16 (2), 117-118
DOI 10.1080/1744666X.2019.1707665, PubMed 31858856

Hoffmann-Vold AM, Fretheim H, Meier C, Maurer B (2020)
Circulating biomarkers of systemic sclerosis - interstitial lung disease
J Scleroderma Relat Disord, 5 (2 Suppl), 41-47
DOI 10.1177/2397198319894851, PubMed 35382223

Lemmers JM, Fretheim H, Knaapen HK, van den Hoogen FH, van Haren-Willems JH, Duijnhouwer AL, van Dijk AP, van den Ende CH, Hoffmann-Vold AM, Vonk MC (2020)
Selexipag treatment in patients with systemic sclerosis-associated pulmonary arterial hypertension in clinical practice, a case series
J Scleroderma Relat Disord, 5 (3), NP7-NP11
DOI 10.1177/2397198320916082, PubMed 35382522

Publications 2019

Elhai M, Hoffmann-Vold AM, Avouac J, Pezet S, Cauvet A, Leblond A, Fretheim H, Garen T, Kuwana M, Molberg Ø, Allanore Y (2019)
Performance of Candidate Serum Biomarkers for Systemic Sclerosis-Associated Interstitial Lung Disease
Arthritis Rheumatol, 71 (6), 972-982
DOI 10.1002/art.40815, PubMed 30624031

Hoffmann-Vold AM, Fretheim H, Halse AK, Seip M, Bitter H, Wallenius M, Garen T, Salberg A, Brunborg C, Midtvedt Ø, Lund MB, Aaløkken TM, Molberg Ø (2019)
Tracking Impact of Interstitial Lung Disease in Systemic Sclerosis in a Complete Nationwide Cohort
Am J Respir Crit Care Med, 200 (10), 1258-1266
DOI 10.1164/rccm.201903-0486OC, PubMed 31310156

Tennøe AH, Murbræch K, Andreassen JC, Fretheim H, Midtvedt Ø, Garen T, Dalen H, Gude E, Andreassen A, Aakhus S, Molberg Ø, Hoffmann-Vold AM (2019)
Systolic Dysfunction in Systemic Sclerosis: Prevalence and Prognostic Implications
ACR Open Rheumatol, 1 (4), 258-266
DOI 10.1002/acr2.1037, PubMed 31777802

Publications 2018

Hoffmann-Vold AM, Fretheim H, Midtvedt Ø, Kilian K, Angelshaug M, Chaudhary A, Gunnarsson R, Brunborg C, Garen T, Andreassen AK, Gude E, Molberg Ø (2018)
Frequencies of borderline pulmonary hypertension before and after the DETECT algorithm: results from a prospective systemic sclerosis cohort
Rheumatology (Oxford), 57 (3), 480-487
DOI 10.1093/rheumatology/kex435, PubMed 29237073

Hoffmann-Vold AM, Hesselstrand R, Fretheim H, Ueland T, Andreassen AK, Brunborg C, Palchevskiy V, Midtvedt Ø, Garen T, Aukrust P, Belperio JA, Molberg Ø (2018)
CCL21 as a Potential Serum Biomarker for Pulmonary Arterial Hypertension in Systemic Sclerosis
Arthritis Rheumatol, 70 (10), 1644-1653
DOI 10.1002/art.40534, PubMed 29687634

Tennøe AH, Murbræch K, Andreassen JC, Fretheim H, Garen T, Gude E, Andreassen A, Aakhus S, Molberg Ø, Hoffmann-Vold AM (2018)
Left Ventricular Diastolic Dysfunction Predicts Mortality in Patients With Systemic Sclerosis
J Am Coll Cardiol, 72 (15), 1804-1813
DOI 10.1016/j.jacc.2018.07.068, PubMed 30286924

Wu W, Jordan S, Becker MO, Dobrota R, Maurer B, Fretheim H, Ye S, Siegert E, Allanore Y, Hoffmann-Vold AM, Distler O (2018)
Prediction of progression of interstitial lung disease in patients with systemic sclerosis: the SPAR model
Ann Rheum Dis, 77 (9), 1326-1332
DOI 10.1136/annrheumdis-2018-213201, PubMed 29875097

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