Vidar Gundersen

  • Professor, Consulant Neurologist; MD, PhD

Publications 2023

Holm H, Gundersen V, Dietrichs E (2023)
Vascular parkinsonism
Tidsskr Nor Laegeforen, 143 (7)
DOI 10.4045/tidsskr.22.0539, PubMed 37158514

Publications 2021

Gundersen V (2021)
Parkinson's Disease: Can Targeting Inflammation Be an Effective Neuroprotective Strategy?
Front Neurosci, 14, 580311
DOI 10.3389/fnins.2020.580311, PubMed 33716638

Gundersen V, Skar M, Flemsaeter F, Kohler B (2021)
A river runs through the landscape: Everyday use in an ever changing environment
J. Rural Stud., 87, 67-76
DOI 10.1016/j.jrurstud.2021.08.022

Publications 2020

Gundersen V (2020)
Tidsskr. Nor. Laegeforen., 140 (13), 1388

Nordengen K, Morland C, Slusher BS, Gundersen V (2020)
Dendritic Localization and Exocytosis of NAAG in the Rat Hippocampus
Cereb Cortex, 30 (3), 1422-1435
DOI 10.1093/cercor/bhz176, PubMed 31504271

Nysveen I, Jusufovic M, Luth SM, Gundersen V, Skogseid IM (2020)
A man in his fifties with increasing motor fluctuations, sleep impairment and altered mental status
Tidsskr Nor Laegeforen, 140 (14)
DOI 10.4045/tidsskr.19.0765, PubMed 33070587

Nysveen I, Jusufovic M, Luth SM, Gundersen V, Skogseid IM (2020)
A man in his 50s with increasing motor fluctuations, difficulty sleeping and mental change
Tidsskr. Nor. Laegeforen., 140 (14), 1468-1472

Ormel L, Lauritzen KH, Schreiber R, Kunzelmann K, Gundersen V (2020)
GABA, but Not Bestrophin-1, Is Localized in Astroglial Processes in the Mouse Hippocampus and the Cerebellum
Front Mol Neurosci, 13, 135
DOI 10.3389/fnmol.2020.00135, PubMed 32848599

Qureshi T, Bjørkmo M, Nordengen K, Gundersen V, Utheim TP, Watne LO, Storm-Mathisen J, Hassel B, Chaudhry FA (2020)
Slc38a1 Conveys Astroglia-Derived Glutamine into GABAergic Interneurons for Neurotransmitter GABA Synthesis
Cells, 9 (7)
DOI 10.3390/cells9071686, PubMed 32668809

Publications 2018

Morland C, Frøland AS, Pettersen MN, Storm-Mathisen J, Gundersen V, Rise F, Hassel B (2018)
Propionate enters GABAergic neurons, inhibits GABA transaminase, causes GABA accumulation and lethargy in a model of propionic acidemia
Biochem J, 475 (4), 749-758
DOI 10.1042/BCJ20170814, PubMed 29339464

Petrelli F, Dallérac G, Pucci L, Calì C, Zehnder T, Sultan S, Lecca S, Chicca A, Ivanov A, Asensio CS, Gundersen V, Toni N, Knott GW, Magara F, Gertsch J, Kirchhoff F, Déglon N, Giros B, Edwards RH, Mothet JP, Bezzi P (2018)
Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments
Mol Psychiatry, 25 (4), 732-749
DOI 10.1038/s41380-018-0226-y, PubMed 30127471

Publications 2017

Gundersen V, Stange EE, Kaltenborn BP, Vistad OI (2017)
Public visual preferences for dead wood in natural boreal forests: The effects of added information
Landsc. Urban Plan., 158, 12-24
DOI 10.1016/j.landurbplan.2016.09.020

Jusufovic M, Gundersen V (2017)
[Stooped neck]
Tidsskr Nor Laegeforen, 137 (9), 636
DOI 10.4045/tidsskr.16.0993, PubMed 28468480

Prydz A, Stahl K, Puchades M, Davarpaneh N, Nadeem M, Ottersen OP, Gundersen V, Amiry-Moghaddam M (2017)
Subcellular expression of aquaporin-4 in substantia nigra of normal and MPTP-treated mice
Neuroscience, 359, 258-266
DOI 10.1016/j.neuroscience.2017.07.029, PubMed 28735099

Publications 2016

Gundersen V, Skar M, O'Brien L, Wold LC, Follo G (2016)
Children and nearby nature: A nationwide parental survey from Norway
Urban For. Urban Green., 17, 116-125
DOI 10.1016/j.ufug.2016.04.002

Publications 2015

Gundersen V, Storm-Mathisen J, Bergersen LH (2015)
Neuroglial Transmission
Physiol Rev, 95 (3), 695-726
DOI 10.1152/physrev.00024.2014, PubMed 26084688

Stensrud MJ, Sogn CJ, Gundersen V (2015)
Immunogold characteristics of VGLUT3-positive GABAergic nerve terminals suggest corelease of glutamate
J Comp Neurol, 523 (18), 2698-713
DOI 10.1002/cne.23811, PubMed 26010578

Publications 2013

Ersland KM, Håvik B, Rinholm JE, Gundersen V, Stansberg C, Steen VM (2013)
LOC689986, a unique gene showing specific expression in restricted areas of the rodent neocortex
BMC Neurosci, 14, 68
DOI 10.1186/1471-2202-14-68, PubMed 23844656

Nagelhus EA, Amiry-Moghaddam M, Bergersen LH, Bjaalie JG, Eriksson J, Gundersen V, Leergaard TB, Morth JP, Storm-Mathisen J, Torp R, Walhovd KB, Tønjum T (2013)
The glia doctrine: addressing the role of glial cells in healthy brain ageing
Mech Ageing Dev, 134 (10), 449-59
DOI 10.1016/j.mad.2013.10.001, PubMed 24141107

Nordengen K, Heuser C, Rinholm JE, Matalon R, Gundersen V (2013)
Localisation of N-acetylaspartate in oligodendrocytes/myelin
Brain Struct Funct, 220 (2), 899-917
DOI 10.1007/s00429-013-0691-7, PubMed 24379086

Puchades M, Sogn CJ, Maehlen J, Bergersen LH, Gundersen V (2013)
Unaltered lactate and glucose transporter levels in the MPTP mouse model of Parkinson's disease
J Parkinsons Dis, 3 (3), 371-85
DOI 10.3233/JPD-130190, PubMed 23963315

Sogn CJ, Puchades M, Gundersen V (2013)
Rare contacts between synapses and microglial processes containing high levels of Iba1 and actin--a postembedding immunogold study in the healthy rat brain
Eur J Neurosci, 38 (1), 2030-40
DOI 10.1111/ejn.12213, PubMed 23590220

Stensrud MJ, Chaudhry FA, Leergaard TB, Bjaalie JG, Gundersen V (2013)
Vesicular glutamate transporter-3 in the rodent brain: vesicular colocalization with vesicular γ-aminobutyric acid transporter
J Comp Neurol, 521 (13), 3042-56
DOI 10.1002/cne.23331, PubMed 23633129

Stensrud MJ, Puchades M, Gundersen V (2013)
GABA is localized in dopaminergic synaptic vesicles in the rodent striatum
Brain Struct Funct, 219 (6), 1901-12
DOI 10.1007/s00429-013-0609-4, PubMed 23851655

Publications 2012

Berg LK, Larsson M, Morland C, Gundersen V (2012)
Pre- and postsynaptic localization of NMDA receptor subunits at hippocampal mossy fibre synapses
Neuroscience, 230, 139-50
DOI 10.1016/j.neuroscience.2012.10.061, PubMed 23159309

Morland C, Nordengen K, Gundersen V (2012)
Valproate causes reduction of the excitatory amino acid aspartate in nerve terminals
Neurosci Lett, 527 (2), 100-4
DOI 10.1016/j.neulet.2012.08.042, PubMed 22963924

Morland C, Nordengen K, Larsson M, Prolo LM, Farzampour Z, Reimer RJ, Gundersen V (2012)
Vesicular uptake and exocytosis of L-aspartate is independent of sialin
FASEB J, 27 (3), 1264-74
DOI 10.1096/fj.12-206300, PubMed 23221336

Ormel L, Stensrud MJ, Chaudhry FA, Gundersen V (2012)
A distinct set of synaptic-like microvesicles in atroglial cells contain VGLUT3
Glia, 60 (9), 1289-300
DOI 10.1002/glia.22348, PubMed 22573606

Publications 2011

Bergersen LH, Morland C, Ormel L, Rinholm JE, Larsson M, Wold JF, Røe AT, Stranna A, Santello M, Bouvier D, Ottersen OP, Volterra A, Gundersen V (2011)
Immunogold detection of L-glutamate and D-serine in small synaptic-like microvesicles in adult hippocampal astrocytes
Cereb Cortex, 22 (7), 1690-7
DOI 10.1093/cercor/bhr254, PubMed 21914633

Gammelsaeter R, Coppola T, Marcaggi P, Storm-Mathisen J, Chaudhry FA, Attwell D, Regazzi R, Gundersen V (2011)
A role for glutamate transporters in the regulation of insulin secretion
PLoS One, 6 (8), e22960
DOI 10.1371/journal.pone.0022960, PubMed 21853059

Larsson M, Morland C, Poblete-Naredo I, Biber J, Danbolt NC, Gundersen V (2011)
The sodium-dependent inorganic phosphate transporter SLC34A1 (NaPi-IIa) is not localized in the mouse brain: a case of tissue-specific antigenic cross-reactivity
J Histochem Cytochem, 59 (9), 807-12
DOI 10.1369/0022155411411713, PubMed 21606201

Larsson M, Sawada K, Morland C, Hiasa M, Ormel L, Moriyama Y, Gundersen V (2011)
Functional and anatomical identification of a vesicular transporter mediating neuronal ATP release
Cereb Cortex, 22 (5), 1203-14
DOI 10.1093/cercor/bhr203, PubMed 21810784

Ormel L, Stensrud MJ, Bergersen LH, Gundersen V (2011)
VGLUT1 is localized in astrocytic processes in several brain regions
Glia, 60 (2), 229-38
DOI 10.1002/glia.21258, PubMed 22009457

Toft M, Lilleeng B, Ramm-Pettersen J, Skogseid IM, Gundersen V, Gerdts R, Pedersen L, Skjelland M, Røste GK, Dietrichs E (2011)
Long-term efficacy and mortality in Parkinson's disease patients treated with subthalamic stimulation
Mov Disord, 26 (10), 1931-4
DOI 10.1002/mds.23817, PubMed 21656853

Publications 2010

Gundersen V (2010)
Protein aggregation in Parkinson's disease
Acta Neurol Scand Suppl (190), 82-7
DOI 10.1111/j.1600-0404.2010.01382.x, PubMed 20586742

Publications 2009

Gammelsaeter R, Jenstad M, Bredahl MK, Gundersen V, Chaudhry FA (2009)
Complementary expression of SN1 and SAT2 in the islets of Langerhans suggests concerted action of glutamine transport in the regulation of insulin secretion
Biochem Biophys Res Commun, 381 (3), 378-82
DOI 10.1016/j.bbrc.2009.02.062, PubMed 19233140

Publications 2008

Bergersen LH, Gundersen V (2008)
Morphological evidence for vesicular glutamate release from astrocytes
Neuroscience, 158 (1), 260-5
DOI 10.1016/j.neuroscience.2008.03.074, PubMed 18479831

Bergersen LH, Storm-Mathisen J, Gundersen V (2008)
Immunogold quantification of amino acids and proteins in complex subcellular compartments
Nat Protoc, 3 (1), 144-52
DOI 10.1038/nprot.2007.525, PubMed 18193031

Furness DN, Dehnes Y, Akhtar AQ, Rossi DJ, Hamann M, Grutle NJ, Gundersen V, Holmseth S, Lehre KP, Ullensvang K, Wojewodzic M, Zhou Y, Attwell D, Danbolt NC (2008)
A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: new insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2)
Neuroscience, 157 (1), 80-94
DOI 10.1016/j.neuroscience.2008.08.043, PubMed 18805467

Gundersen V (2008)
Co-localization of excitatory and inhibitory transmitters in the brain
Acta Neurol Scand Suppl, 188, 29-33
DOI 10.1111/j.1600-0404.2008.01028.x, PubMed 18439218

Holten AT, Danbolt NC, Shimamoto K, Gundersen V (2008)
Low-affinity excitatory amino acid uptake in hippocampal astrocytes: a possible role of Na+/dicarboxylate cotransporters
Glia, 56 (9), 990-7
DOI 10.1002/glia.20672, PubMed 18442087

Publications 2007

Holten AT, Gundersen V (2007)
Glutamine as a precursor for transmitter glutamate, aspartate and GABA in the cerebellum: a role for phosphate-activated glutaminase
J Neurochem, 104 (4), 1032-42
DOI 10.1111/j.1471-4159.2007.05065.x, PubMed 17986214

Jourdain P, Bergersen LH, Bhaukaurally K, Bezzi P, Santello M, Domercq M, Matute C, Tonello F, Gundersen V, Volterra A (2007)
Glutamate exocytosis from astrocytes controls synaptic strength
Nat Neurosci, 10 (3), 331-9
DOI 10.1038/nn1849, PubMed 17310248

Nguyen NH, Morland C, Gonzalez SV, Rise F, Storm-Mathisen J, Gundersen V, Hassel B (2007)
Propionate increases neuronal histone acetylation, but is metabolized oxidatively by glia. Relevance for propionic acidemia
J Neurochem, 101 (3), 806-14
DOI 10.1111/j.1471-4159.2006.04397.x, PubMed 17286595

Nicolaysen A, Gammelsaeter R, Storm-Mathisen J, Gundersen V, Iversen PO (2007)
The components required for amino acid neurotransmitter signaling are present in adipose tissues
J Lipid Res, 48 (10), 2123-32
DOI 10.1194/jlr.M700021-JLR200, PubMed 17600303

Publications 2006

Dietrichs E, Gundersen V (2006)
[Glutamate--the most important transmitter in the brain]
Tidsskr Nor Laegeforen, 126 (20), 2643
PubMed 17057761

Vikne H, Refsnes PE, Ekmark M, Medbø JI, Gundersen V, Gundersen K (2006)
Muscular performance after concentric and eccentric exercise in trained men
Med Sci Sports Exerc, 38 (10), 1770-81
DOI 10.1249/01.mss.0000229568.17284.ab, PubMed 17019299

Publications 2004

Bezzi P, Gundersen V, Galbete JL, Seifert G, Steinhäuser C, Pilati E, Volterra A (2004)
Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate
Nat Neurosci, 7 (6), 613-20
DOI 10.1038/nn1246, PubMed 15156145

Boulland JL, Qureshi T, Seal RP, Rafiki A, Gundersen V, Bergersen LH, Fremeau RT, Edwards RH, Storm-Mathisen J, Chaudhry FA (2004)
Expression of the vesicular glutamate transporters during development indicates the widespread corelease of multiple neurotransmitters
J Comp Neurol, 480 (3), 264-80
DOI 10.1002/cne.20354, PubMed 15515175

Gammelsaeter R, Frøyland M, Aragón C, Danbolt NC, Fortin D, Storm-Mathisen J, Davanger S, Gundersen V (2004)
Glycine, GABA and their transporters in pancreatic islets of Langerhans: evidence for a paracrine transmitter interplay
J Cell Sci, 117 (Pt 17), 3749-58
DOI 10.1242/jcs.01209, PubMed 15252115

Gundersen V, Holten AT, Storm-Mathisen J (2004)
GABAergic synapses in hippocampus exocytose aspartate on to NMDA receptors: quantitative immunogold evidence for co-transmission
Mol Cell Neurosci, 26 (1), 156-65
DOI 10.1016/j.mcn.2004.01.017, PubMed 15121187

Publications 2003

Bergersen L, Ruiz A, Bjaalie JG, Kullmann DM, Gundersen V (2003)
GABA and GABAA receptors at hippocampal mossy fibre synapses
Eur J Neurosci, 18 (4), 931-41
DOI 10.1046/j.1460-9568.2003.02828.x, PubMed 12925019

Publications 2002

Gundersen V (2002)
Anrikning av Artemia og rotatoria med marine fosfolipider
Institutt for marin bioteknologi, Norges fiskerihøgskole,Universitetet i Tromsø, Tromsø, 57 s.
BIBSYS 023023198

Publications 2001

Gundersen V, Fonnum F, Ottersen OP, Storm-Mathisen J (2001)
Redistribution of neuroactive amino acids in hippocampus and striatum during hypoglycemia: a quantitative immunogold study
J Cereb Blood Flow Metab, 21 (1), 41-51
DOI 10.1097/00004647-200101000-00006, PubMed 11149667

Publications 2000

Gundersen V, Dietrichs E (2000)
Neuroprotection and parkinsonism
Can J Neurol Sci, 27 (3), 261
PubMed 10975542

Publications 1998

Gundersen V (1998)
Multivariate signal analysis - empirical modelling of drilling riser feasibility study
Høgskolen i Telemark, Avdeling for teknologiske fag, Porsgrunn, 131 bl.
BIBSYS 981985610

Gundersen V, Chaudhry FA, Bjaalie JG, Fonnum F, Ottersen OP, Storm-Mathisen J (1998)
Synaptic vesicular localization and exocytosis of L-aspartate in excitatory nerve terminals: a quantitative immunogold analysis in rat hippocampus
J Neurosci, 18 (16), 6059-70
DOI 10.1523/JNEUROSCI.18-16-06059.1998, PubMed 9698301

Weaver CD, Gundersen V, Verdoorn TA (1998)
A high affinity glutamate/aspartate transport system in pancreatic islets of Langerhans modulates glucose-stimulated insulin secretion
J Biol Chem, 273 (3), 1647-53
DOI 10.1074/jbc.273.3.1647, PubMed 9430708

Publications 1996

Gundersen V, Ottersen OP, Storm-Mathisen J (1996)
Selective excitatory amino acid uptake in glutamatergic nerve terminals and in glia in the rat striatum: quantitative electron microscopic immunocytochemistry of exogenous (D)-aspartate and endogenous glutamate and GABA
Eur J Neurosci, 8 (4), 758-65
DOI 10.1111/j.1460-9568.1996.tb01261.x, PubMed 9081627

Publications 1995

Gundersen V (1995)
The synaptic handling of aspartate at excitatory synapsesin the brain: quantitative light and electron microscopic immunocytochemistry
Department of Anatomy, Institute of Basic Medical Sciences, University of Oslo, [Oslo], 1 b. (flere pag.)
BIBSYS 960233334, ISBN 82-91061-68-8

Gundersen V, Shupliakov O, Brodin L, Ottersen OP, Storm-Mathisen J (1995)
Quantification of excitatory amino acid uptake at intact glutamatergic synapses by immunocytochemistry of exogenous D-aspartate
J Neurosci, 15 (6), 4417-28
DOI 10.1523/JNEUROSCI.15-06-04417.1995, PubMed 7790917

Publications 1993

Gundersen V, Danbolt NC, Ottersen OP, Storm-Mathisen J (1993)
Demonstration of glutamate/aspartate uptake activity in nerve endings by use of antibodies recognizing exogenous D-aspartate
Neuroscience, 57 (1), 97-111
DOI 10.1016/0306-4522(93)90114-u, PubMed 7904057

Snyder GL, Fisone G, Morino P, Gundersen V, Ottersen OP, Hökfelt T, Greengard P (1993)
Regulation by the neuropeptide cholecystokinin (CCK-8S) of protein phosphorylation in the neostriatum
Proc Natl Acad Sci U S A, 90 (23), 11277-81
DOI 10.1073/pnas.90.23.11277, PubMed 8248241

Publications 1991

Gundersen V, Ottersen OP, Storm-Mathisen J (1991)
Aspartate- and Glutamate-like Immunoreactivities in Rat Hippocampal Slices: Depolarization-induced Redistribution and Effects of Precursors
Eur J Neurosci, 3 (12), 1281-1299
DOI 10.1111/j.1460-9568.1991.tb00061.x, PubMed 12106226

Publications 1990

Ottersen OP, Storm-Mathisen J, Bramham C, Torp R, Laake J, Gundersen V (1990)
A quantitative electron microscopic immunocytochemical study of the distribution and synaptic handling of glutamate in rat hippocampus
Prog Brain Res, 83, 99-114
DOI 10.1016/s0079-6123(08)61244-3, PubMed 1975455

Publications 1986

Storm-Mathisen J, Ottersen OP, Fu-Long T, Gundersen V, Laake JH, Nordbø G (1986)
Metabolism and transport of amino acids studied by immunocytochemistry
Med Biol, 64 (2-3), 127-32
PubMed 2875229

Page visits: 7869