Leif Erik Vinge
- Consultant Cardiologist, MD, PhD
Publications 2020
YKL-40 (Chitinase-3-Like Protein 1) Serum Levels in Aortic Stenosis
Circ.-Heart Fail., 13 (10), e006643
DOI 10.1161/CIRCHEARTFAILURE.119.006643
Sarcoma of the heart
Tidsskr. Nor. Laegeforen., 140 (6), 582-583
Publications 2019
Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction
EBioMedicine, 46, 264-273
DOI 10.1016/j.ebiom.2019.07.024
Mammalian Target of Rapamycin (mTOR) and the Proteasome Attenuates IL-1 beta Expression in Primary Mouse Cardiac Fibroblasts
Front. Immunol., 10, 1285
DOI 10.3389/fimmu.2019.01285
Publications 2017
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
J. Mol. Med., 95 (7), 767-777
DOI 10.1007/s00109-017-1529-1
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
Mediat. Inflamm., 2017, 9450439
DOI 10.1155/2017/9450439
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Reports, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009
Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts
Biochim. Biophys. Acta Mol. Cell Biol. Lipids, 1862 (2), 234-245
DOI 10.1016/j.bbalip.2016.11.003
Publications 2016
Low Circulating Levels of Mitochondrial and High Levels of Nuclear DNA Predict Mortality in Chronic Heart Failure
J. Card. Fail., 22 (10), 823-828
DOI 10.1016/j.cardfail.2016.06.013
NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective
Biochem. Biophys. Res. Commun., 469 (4), 1012-1020
DOI 10.1016/j.bbrc.2015.12.051
Publications 2015
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice
PLoS One, 10 (10), e0139715
DOI 10.1371/journal.pone.0139715
Altered Levels of Fatty Acids and Inflammatory and Metabolic Mediators in Epicardial Adipose Tissue in Patients With Systolic Heart Failure
J. Card. Fail., 21 (11), 916-923
DOI 10.1016/j.cardfail.2015.07.014
Publications 2014
The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure
J. Intern. Med., 275 (6), 621-630
DOI 10.1111/joim.12175
p38 alpha regulates SERCA2a function
J. Mol. Cell. Cardiol., 67, 86-93
DOI 10.1016/j.yjmcc.2013.12.005
Toll-Like Receptor 9 Mediated Responses in Cardiac Fibroblasts
PLoS One, 9 (8), e104398
DOI 10.1371/journal.pone.0104398
Toll-Like Receptor 9-Activation during Onset of Myocardial Ischemia Does Not Influence Infarct Extension
PLoS One, 9 (8), e104407
DOI 10.1371/journal.pone.0104407
Publications 2013
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemiareperfusion injury
Cardiovasc. Res., 99 (1), 164-174
DOI 10.1093/cvr/cvt091
A role for NLRP3 inflammasome in acute myocardial ischaemia-reperfusion injury? Reply
Cardiovasc. Res., 99 (1), 226-227
DOI 10.1093/cvr/cvt130
Publications 2012
Increased circulating mitochondrial DNA after myocardial infarction
Int. J. Cardiol., 158 (1), 132-134
DOI 10.1016/j.ijcard.2012.04.047
Inflammatory Cytokines in Heart Failure: Mediators and Markers
Cardiology, 122 (1), 23-35
DOI 10.1159/000338166
Cardiomyocyte-restricted inhibition of G protein-coupled receptor kinase-3 attenuates cardiac dysfunction after chronic pressure overload
Am. J. Physiol.-Heart Circul. Physiol., 303 (1), H66-H74
DOI 10.1152/ajpheart.00724.2011
Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
J. Appl. Physiol., 112 (8), 1372-1382
DOI 10.1152/japplphysiol.01350.2011
The Homeostatic Chemokine CCL21 Predicts Mortality and May Play a Pathogenic Role in Heart Failure
PLoS One, 7 (3), e33038
DOI 10.1371/journal.pone.0033038
Publications 2011
Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemia-reperfusion injury
Am. J. Physiol.-Heart Circul. Physiol., 300 (4), H1291-H1302
DOI 10.1152/ajpheart.00604.2010
Tumor necrosis factor superfamily molecules in acute coronary syndromes
Ann. Med., 43 (2), 90-103
DOI 10.3109/07853890.2010.523711
Krill oil attenuates left ventricular dilatation after myocardial infarction in rats
Lipids Health Dis., 10, 245
DOI 10.1186/1476-511X-10-245
Lack of Chemokine Signaling through CXCR5 Causes Increased Mortality, Ventricular Dilatation and Deranged Matrix during Cardiac Pressure Overload
PLoS One, 6 (4), e18668
DOI 10.1371/journal.pone.0018668
Publications 2010
Adrenomedullin is increased in alveolar macrophages and released from the lungs into the circulation in severe heart failure
Basic Res. Cardiol., 105 (1), 89-98
DOI 10.1007/s00395-009-0070-y
Publications 2009
Increased Production of CXCL16 in Experimental and Clinical Heart Failure A Possible Role in Extracellular Matrix Remodeling
Circ.-Heart Fail., 2 (6), 624-632
DOI 10.1161/CIRCHEARTFAILURE.108.821074
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure
Eur. Heart J., 30 (10), 1229-1236
DOI 10.1093/eurheartj/ehp088
Up-regulation of myocardial DNA base excision repair activities in experimental heart failure
Mutat. Res.-Fundam. Mol. Mech. Mutagen., 666 (1-2), 32-38
DOI 10.1016/j.mrfmmm.2009.03.008
Publications 2008
Increased expression of LIGHT/TNFSF 14 and its receptors in experimental and clinical heart failure
Eur. J. Heart Fail., 10 (4), 352-359
DOI 10.1016/j.ejheart.2008.02.010
Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress
Circulation, 117 (11), 1378-1387
DOI 10.1161/CIRCULATIONAHA.107.752618
Endothelial S100A1 modulates vascular function via nitric oxide
Circ.Res., 102 (7), 786-794
DOI 10.1161/CIRCRESAHA.108.172031
Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 uncovers distinct functions of GRK3 in regulation of cardiac contractility and growth - GRK3 controls cardiac alpha(1)-adrenergic receptor responsiveness
J. Biol. Chem., 283 (16), 10601-10610
DOI 10.1074/jbc.M708912200
Publications 2007
Induction of pulmonary connective tissue growth factor in heart failure is associated with pulmonary parenchymal and vascular remodeling
Cardiovasc. Res., 74 (2), 323-333
DOI 10.1016/j.cardiores.2006.12.010
Substrate specificities of G protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function
Mol. Pharmacol., 72 (3), 582-591
DOI 10.1124/mol.107.035766
Publications 2006
Increased expression and function of the myocardial Na-K-2Cl cotransporter in failing rat hearts
Basic Res. Cardiol., 101 (6), 471-478
DOI 10.1007/s00395-006-0604-5
Myocardial G protein-coupled receptor kinases: distinct isoform specificities at receptors as basis for diverse roles in regulation of cardiac function
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 362, 1 b. (flere pag.)
BIBSYS 05229658x, ISBN 82-8072-661-6
Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats
Eur. J. Heart Fail., 8 (8), 790-796
DOI 10.1016/j.ejheart.2006.02.007